CN108288427A - A kind of production method of 3 D-printing transtracheal mirror lymph node puncture training pattern - Google Patents

A kind of production method of 3 D-printing transtracheal mirror lymph node puncture training pattern Download PDF

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Publication number
CN108288427A
CN108288427A CN201810012746.2A CN201810012746A CN108288427A CN 108288427 A CN108288427 A CN 108288427A CN 201810012746 A CN201810012746 A CN 201810012746A CN 108288427 A CN108288427 A CN 108288427A
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air flue
model
lymph node
simulation
training pattern
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王洵
鞠沛楠
赵弘卿
沈露萍
刘炀
强鑫垚
钱雯雯
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Wuxi No 2 Peoples Hospital
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    • GPHYSICS
    • G09EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09BEDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G09B23/28Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
    • G09B23/285Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine for injections, endoscopy, bronchoscopy, sigmoidscopy, insertion of contraceptive devices or enemas
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00Processes of additive manufacturing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B33ADDITIVE MANUFACTURING TECHNOLOGY
    • B33YADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y50/00Data acquisition or data processing for additive manufacturing

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Abstract

The present invention provides a kind of production method of 3 D-printing transtracheal mirror lymph node puncture training pattern, step is:First pass through the throat of CT tomoscans and three-dimensional reconstruction acquisition different people, the structural information of trachea-bronchial epithelial cell, multiple air flue models for meeting clinical real anatomy are produced using three-dimensional printing technology, then the simulation lymph node for being sticked to bronchus lateral wall corresponding position is made, emulate gnathode and the shell for blocking and fixing bronchus model, finally each component is assembled by anatomical position, outermost layer is covered with shell;The method of the making transtracheal mirror lymph node puncture training pattern of the present invention makes the air passage structure of training pattern approximate with the structure height of true case, the structure and complexity of multiple air flue models are different in training pattern, so that training process is more nearly clinical true operation environment, training process from the easier to the more advanced, improves training effect.

Description

A kind of production method of 3 D-printing transtracheal mirror lymph node puncture training pattern
Technical field
The present invention relates to a kind of training patterns of bronchoscope, and in particular to a kind of 3 D-printing transtracheal mirror lymph node is worn The production method for piercing training pattern.
Background technology
It is to apply a kind of special puncture needle with flexible conduit through Aspiration-needle biopsy art, passes through fiber branch The biopsy duct of airway wall is sent into air flue, is then penetrated airway walls to lesion outside trachea-bronchial epithelial cell chamber, such as tubercle, lump, is swollen The lesion of big lymph node and lung is drawn into hand-manipulating of needle piercing and sucking, is obtained cell or tissue sample and is carried out cytology and pathological examination A kind of new technology.It is widely used in being close to the etiologic diagnosis of lesion around trachea-bronchial epithelial cell through Aspiration-needle biopsy art, And bronchoscope technology is made to participate in the clinical stages of malignant tumour, but before the grasp that is skilled in technique to this, do not allow Patient body directly operates.And training at present mostly virtual bronchoscopic analogue technique and fabric bronchoscope training box, these Though the prior art can carry out operation training, each tissue of respiratory system, organ model specific form and true also have Gap, relative tertiary location and adjacent structure are not definite enough, and the selection of material is also unreasonable, and training pattern bronchus structure thousand A piece without exception, does not have difficulty difference, so cannot reach clinical practice requirement well, trainer cannot skillfully grasp through bronchus Flow, skill and the gimmick of mirror needle biopsy art operation.
3-D scanning is mainly used for being scanned object space shape and structure and color, to obtain the sky of body surface Between coordinate, the data collected can be used for three-dimensional reconstruction calculating, create the digital model file of actual object, have height Efficiency, high-precision feature.Three-dimensional printing technology can be glued based on digital model file with powdery metal or plastic etc. Condensation material constructs object by layer-by-layer printing.
Invention content
In order to solve the problems in the existing technology, the present invention provides a kind of 3 D-printing transtracheal mirror lymph nodes to wear The production method for piercing training pattern so that the bronchus structure of training pattern was trained closer to the anatomical structure of true case There are multiple models of difficulty or ease varying degree available in journey, improves training effect.
Technical proposal that the invention solves the above-mentioned problems is:A kind of 3 D-printing transtracheal mirror lymph node puncture training pattern Production method, specifically include following steps:
Step 1:Low difficulty, middle difficulty, each five of highly difficult patient are chosen, is acquired by CT tomoscans and three-dimensional reconstruction Their throat, the structural information of trachea-bronchial epithelial cell, obtain three-dimensional modeling data;
Step 2:Using the three-dimensional modeling data obtained in computer software read step 1, is restored and repaired, accordingly generated The threedimensional model of air flue model;
Step 3:Using three-dimensional printer, the three dimensional model printing of each air flue model is molded, is accorded with to obtain multiple both height Real anatomy and the air flue model of individuation are closed, the tracheae loop section of air flue model uses resin material, tracheal wall soft It includes from top to bottom including simulation throat, simulation tracheae portion and simulation bronchus portion that part, which uses silica gel material, air flue model,;
Step 4:Simulation lymph node, the hollow ball that simulation lymph junction configuration is diameter 5mm ~ 10mm are made using silica gel material Shape, inside filling soft tissue, the soft tissue is plasticine or glycerine or paraffin oil, can be replaced after being used for multiple times;
Step 5:Gnathode is made using silica gel, metal material, which is when being inserted into bronchoscope as insert port Position, shape be true jaw simulation model, be directed to human body implement when the case where to improve training effect, in gnathode Equipped with larynx portion, the end in the larynx portion is connected with the simulation throat of air flue model, as needed can integrally replace air flue model It changes;
Step 6:Select transparent plastics material make shell, and hull outside face selectively covering it is opaque block, shell use In receiving air flue model, face side can be opened, and air flue model installation part is equipped in shell, and air flue model passes through air flue model Installation part is mounted in shell, and the larynx portion of gnathode and the simulation throat of air flue model are assembled, and gnathode setting exists Outside shell, simulation lymph node is sticked at true lymph node position, shell front can be opened after puncturing training and observed Whether lymph node is punctured to;
Further, in step 1 patient's difficulty according to the position, big of airway patency degree, air flue variation situation, diseased region Small, shape judges that the low difficulty of airway patency degree is high, and air flue makes a variation, and big difficulty is high, and diseased region is located at air flue deep, compares Small, shape is difficult to capture difficulty height, while according to positive in the total time and biopsy for carrying out airway wall standard operation to patient Rate, the low air flue sample difficulty of time-consuming length, positive rates of biopsy are high;
Further, in step 2 using the three-dimensional modeling data obtained in computer software read step 1, the specific steps are, The first step:Image is read, is imported CT images in Mimics softwares using image import feature, automatic definition all around four Direction, the both direction up and down of manual definition image, software will automatically generate sagittal plane and coronal-plane figure according to cross-sectional image Picture;Second step:Profile is extracted, into three-view diagram editable operation interface, profile is extracted using threshold value setting means, is ensureing weight It builds in the case that tissue is selected, so that the structure other than reconstruction tissue profile shade is occurred as possible, define threshold value suitable Range is formed masked;Third walks:Hot-zone is selected, hot-zone selection is carried out using the region tool for increasing in software, if necessary to weight Build that structure is close with surrounding tissue gray value, when extraction then needs the method for taking manual identified, and side will be carried out to every tomographic image Fate cuts, removes redundant data, selective editing and filling-up hole processing, the 4th step:Threedimensional model is generated, 3D interpolations, profit are based on Two dimensional image can be directly translated into threedimensional model with the Calculate 3D in the three-dimensional computations of software tool-segmentation menu, The mode shape of reconstruction is true to nature, it is translatable, scaling, arbitrary plane cutting, Arbitrary Rotation, directly clearly reproduce throat, The threedimensional model rebuild is exported with SLT formats and is preserved, you can rebuild by the three-dimensional solid form of trachea-bronchial epithelial cell Three-dimensional visualization model.
The present invention has advantageous effect:
That the present invention can be carried out is can not implementing in existing puncture training pattern, on the inside of tracheae or bronchus to close to tracheae Or the training of puncture technique that bronchial lymph node is punctured;The present invention makes air flue model using three-dimensional printing technology, Its structure is with real anatomy more closely, to make training process closer to clinic;The present invention is by scanning different patients Bronchus structure the training of different difficulty can be produced according to the complexity of the operation of bronchoscope lymph node puncture Model helps to improve the puncture technique of performer so that training is incremental.
Description of the drawings
Fig. 1 is the structural schematic diagram of puncturing pattern;
In figure:1- simulates throat, and 2- simulates tracheae portion, and 3- simulates bronchus portion, 4- gnathodes, 5- larynxes portion, 6- shells, 7- gas Road model installation part.
Specific implementation mode
Below in conjunction with the accompanying drawings and specific implementation mode the present invention is further illustrated.
As shown, a kind of production method of 3 D-printing transtracheal mirror lymph node puncture training pattern, specifically includes Following steps:
Step 1:Low difficulty, middle difficulty, each five of highly difficult patient are chosen, is acquired by CT tomoscans and three-dimensional reconstruction Their throat, the structural information of trachea-bronchial epithelial cell, obtain three-dimensional modeling data;
Step 2:Using the three-dimensional modeling data obtained in computer software read step 1, is restored and repaired, accordingly generated The threedimensional model of air flue model;
Step 3:Using three-dimensional printer, the three dimensional model printing of each air flue model is molded, is accorded with to obtain multiple both height Real anatomy and the air flue model of individuation are closed, the tracheae loop section of air flue model uses resin material, tracheal wall soft It includes from top to bottom including simulation throat, simulation tracheae portion and simulation bronchus portion that part, which uses silica gel material, air flue model,;
Step 4:Simulation lymph node, the hollow ball that simulation lymph junction configuration is diameter 5mm ~ 10mm are made using silica gel material Shape, inside filling soft tissue, the soft tissue is plasticine or glycerine or paraffin oil, can be replaced after being used for multiple times;
Step 5:Gnathode is made using silica gel, metal material, which is when being inserted into bronchoscope as insert port Position, shape be true jaw simulation model, be directed to human body implement when the case where to improve training effect, in gnathode Equipped with larynx portion, the end in the larynx portion is connected with the simulation throat of air flue model, as needed can integrally replace air flue model It changes;
Step 6:Select transparent plastics material make shell, and hull outside face selectively covering it is opaque block, shell use In receiving air flue model, face side can be opened, and air flue model installation part is equipped in shell, and air flue model passes through air flue model Installation part is mounted in shell, and the larynx portion of gnathode and the simulation throat of air flue model are assembled, and gnathode setting exists Outside shell, simulation lymph node is sticked at true lymph node position, shell front can be opened after puncturing training and observed It whether is punctured to lymph node, therefore helps to improve the evaluation effect of this training pattern;
Further, in step 1 patient's difficulty according to the position, big of airway patency degree, air flue variation situation, diseased region Small, shape judges that the low difficulty of airway patency degree is high, and air flue makes a variation, and big difficulty is high, and diseased region is located at air flue deep, compares Small, shape is difficult to capture difficulty height, while according to positive in the total time and biopsy for carrying out airway wall standard operation to patient Rate, the low air flue sample difficulty of time-consuming length, positive rates of biopsy are high;
Further, in step 2 using the three-dimensional modeling data obtained in computer software read step 1, the specific steps are, The first step:Image is read, is imported CT images in Mimics softwares using image import feature, automatic definition all around four Direction, the both direction up and down of manual definition image, software will automatically generate sagittal plane and coronal-plane figure according to cross-sectional image Picture;Second step:Profile is extracted, into three-view diagram editable operation interface, profile is extracted using threshold value setting means, is ensureing weight It builds in the case that tissue is selected, so that the structure other than reconstruction tissue profile shade is occurred as possible, define threshold value suitable Range is formed masked;Third walks:Hot-zone is selected, hot-zone selection is carried out using the region tool for increasing in software, if necessary to weight Build that structure is close with surrounding tissue gray value, when extraction then needs the method for taking manual identified, and side will be carried out to every tomographic image Fate cuts, removes redundant data, selective editing and filling-up hole processing, the 4th step:Threedimensional model is generated, 3D interpolations, profit are based on Two dimensional image can be directly translated into threedimensional model with the Calculate 3D in the three-dimensional computations of software tool-segmentation menu, The mode shape of reconstruction is true to nature, it is translatable, scaling, arbitrary plane cutting, Arbitrary Rotation, directly clearly reproduce throat, The three-dimensional solid form of trachea-bronchial epithelial cell.The threedimensional model rebuild is exported with SLT formats and is preserved, you can is rebuild Three-dimensional visualization model.
When carrying out puncturing trained, trainer uses low difficulty, middle difficulty, highly difficult group of bronchus model training successively, In use, bronchoscope is inserted by trainer from gnathode, the larynx portion through gnathode reaches the simulation tracheae portion of air flue model Or simulation bronchus portion, and pass through using puncture needle the tracheal wall soft tissue of tracheae or bronchial cartilage czermak space, to tracheae or Parabronchus simulation lymph node carries out puncture attraction, and when the soft tissue being attracted in simulation lymph node, expression punctures successfully, The face side that shell can also be opened after piercing directly sees whether to puncture successfully.Trainer trains by relatively low difficulty, Only after the examination of relatively low difficulty passes through, the training of next difficulty can be just carried out, therefore embodiment of the present invention can be carried significantly Training effect of the height through bronchoscope lymph node puncture.
The above described is only a preferred embodiment of the present invention, being not that the invention has other forms of limitations, appoint What those skilled in the art changed or be modified as possibly also with the technology contents of the disclosure above equivalent variations etc. It imitates embodiment and is applied to other fields, but it is every without departing from technical solution of the present invention content, according to the technical essence of the invention To any simple modification, equivalent variations and remodeling made by above example, the protection domain of technical solution of the present invention is still fallen within.

Claims (3)

1. a kind of production method of 3 D-printing transtracheal mirror lymph node puncture training pattern, which is characterized in that it is specifically included Following steps:
Step 1:Low difficulty, middle difficulty, each five of highly difficult patient are chosen, is acquired by CT tomoscans and three-dimensional reconstruction Their throat, the structural information of trachea-bronchial epithelial cell, obtain three-dimensional modeling data;
Step 2:Using the three-dimensional modeling data obtained in computer software read step 1, is restored and repaired, accordingly generated The threedimensional model of air flue model;
Step 3:Using three-dimensional printer, the three dimensional model printing of each air flue model is molded, is accorded with to obtain multiple both height Real anatomy and the air flue model of individuation are closed, the tracheae loop section of air flue model uses resin material, tracheal wall soft It includes from top to bottom including simulation throat, simulation tracheae portion and simulation bronchus portion that part, which uses silica gel material, air flue model,;
Step 4:Simulation lymph node, inside filling soft tissue are made using silica gel material;
Step 5:Gnathode is made using silica gel, metal material, which is when being inserted into bronchoscope as insert port Position, shape are the simulation model of true jaw, and larynx portion, the mould of the end and air flue model in the larynx portion are equipped in gnathode Quasi- throat is connected, and as needed can integrally replace air flue model;
Step 6:Select transparent plastics material make shell, and hull outside face selectively covering it is opaque block, shell use In receiving air flue model, face side can be opened, and air flue model installation part is equipped in shell, and air flue model passes through air flue model Installation part is mounted in shell, and the larynx portion of gnathode and the simulation throat of air flue model are assembled, and gnathode setting exists Outside shell, simulation lymph node is sticked at true lymph node position.
2. a kind of production method of 3 D-printing transtracheal mirror lymph node puncture training pattern as described in claim 1, special Sign is that soft tissue described in step 4 is plasticine or glycerine or paraffin oil.
3. a kind of production method of 3 D-printing transtracheal mirror lymph node puncture training pattern as described in claim 1, special Sign is, the hollow sphere that lymph junction configuration is diameter 5mm ~ 10mm is simulated described in step 4.
CN201810012746.2A 2018-01-06 2018-01-06 A kind of production method of 3 D-printing transtracheal mirror lymph node puncture training pattern Pending CN108288427A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111326228A (en) * 2020-02-19 2020-06-23 清华大学 Method and system for determining lower respiratory tract administration dosage of medicine particles
CN113413212A (en) * 2021-06-28 2021-09-21 哈尔滨理工大学 Method for automatically intervening bronchoscope in tracheal disease diagnosis and treatment operation
CN113920835A (en) * 2021-10-12 2022-01-11 青岛三易三维技术有限公司 Human body model making method and system for interventional operation training based on 3D printing

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CN103153589A (en) * 2011-03-31 2013-06-12 国立大学法人神户大学 Method for manufacturing three-dimensional molded model and support tool for medical treatment, medical training, research, and education
CN103578337A (en) * 2013-11-05 2014-02-12 中国人民解放军第二军医大学 Training model of transbronchial lymphonodus biopsy operation
US20150213731A1 (en) * 2011-11-10 2015-07-30 Koken Co., Ltd. Training model for ultrasonic bronchoscopy
CN105105847A (en) * 2015-07-14 2015-12-02 汤润 3D kidney model printing method for kidney stone surgical simulation teaching
CN204926647U (en) * 2015-07-24 2015-12-30 殷琴 Human training model of emulation of air flue simulation, internal organs and neural retardant puncture

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103153589A (en) * 2011-03-31 2013-06-12 国立大学法人神户大学 Method for manufacturing three-dimensional molded model and support tool for medical treatment, medical training, research, and education
US20150213731A1 (en) * 2011-11-10 2015-07-30 Koken Co., Ltd. Training model for ultrasonic bronchoscopy
CN103578337A (en) * 2013-11-05 2014-02-12 中国人民解放军第二军医大学 Training model of transbronchial lymphonodus biopsy operation
CN105105847A (en) * 2015-07-14 2015-12-02 汤润 3D kidney model printing method for kidney stone surgical simulation teaching
CN204926647U (en) * 2015-07-24 2015-12-30 殷琴 Human training model of emulation of air flue simulation, internal organs and neural retardant puncture

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111326228A (en) * 2020-02-19 2020-06-23 清华大学 Method and system for determining lower respiratory tract administration dosage of medicine particles
CN111326228B (en) * 2020-02-19 2020-10-30 清华大学 Method and system for determining lower respiratory tract administration dosage of medicine particles
CN113413212A (en) * 2021-06-28 2021-09-21 哈尔滨理工大学 Method for automatically intervening bronchoscope in tracheal disease diagnosis and treatment operation
CN113413212B (en) * 2021-06-28 2021-12-31 哈尔滨理工大学 Method for automatically intervening bronchoscope in tracheal disease diagnosis and treatment operation
CN113920835A (en) * 2021-10-12 2022-01-11 青岛三易三维技术有限公司 Human body model making method and system for interventional operation training based on 3D printing

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