CN108236198A - Prepare the brush of rat oral submucosa fibrosis experimental model - Google Patents
Prepare the brush of rat oral submucosa fibrosis experimental model Download PDFInfo
- Publication number
- CN108236198A CN108236198A CN201810062043.0A CN201810062043A CN108236198A CN 108236198 A CN108236198 A CN 108236198A CN 201810062043 A CN201810062043 A CN 201810062043A CN 108236198 A CN108236198 A CN 108236198A
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- China
- Prior art keywords
- brush
- experimental model
- rat oral
- oral submucosa
- submucosa fibrosis
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Classifications
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- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B11/00—Brushes with reservoir or other means for applying substances, e.g. paints, pastes, water
- A46B11/001—Brushes with reservoir or other means for applying substances, e.g. paints, pastes, water with integral reservoirs
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B2200/00—Brushes characterized by their functions, uses or applications
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- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
Abstract
The invention discloses a kind of brushes for preparing rat oral submucosa fibrosis experimental model.The brush for preparing rat oral submucosa fibrosis experimental model includes：Brush holder is formed with liquid storage cavity in the brush holder, and the liquid storage cavity memory contains aqueous areca nut extract；Guide rail；Brush head；More first bristles；Woven hose, one end of the woven hose are connected with the liquid storage cavity, and the other end of the woven hose is connected with first bristle.Partition board；Elastic component, brush head described in the elastic component elastic connection and the partition board；Drive rod, one end of the drive rod are abutted with the brush head, and the other end of the drive rod stretches into the liquid storage cavity；Accelerator rod, the accelerator rod extend, and stretch into the woven hose from the other end bending of the drive rod.The brush simple operation provided by the invention for preparing rat oral submucosa fibrosis experimental model, simulation work well, and have greatly saved the manpower and time cost of experimenter.
Description
Technical field
The present invention relates to biomedicine technical fields, and in particular to a kind of to prepare rat oral submucosa fibrosis experiment mould
The brush of type.
Background technology
Research shows that the extracellular matrixs such as oral submucous fibrosis proliferation, collagen caused by a large amount of betel quid chewings
A large amount of depositions be one of Important cause of disease for leading to oral submucosa fibrosis (Oral Submucous Fibrosis, OSF).
OSF is defined as precancerous condition by the World Health Organization.I-type collagen (collagen type I) is collagen
(collagen) one kind, it is a kind of structural proteins, is the main component of extracellular matrix, and main function is to tissue
Cell is supported and the effect of connection.Research finds that the high expression of I-type collagen and many fibrotic diseases are close
Cut it is relevant, at present it has also been found that I-type collagen in kinds of tumors such as tongue cancer, head and neck scale carcinoma, cancer of pancreas also in high expression.
There is data to show, I-type collagen is expressed conspicuousness in OSF late periods and oral squamous cell carcinomas and increased and more active.Therefore, I
Collagen type may play the part of a very important role during OSF and canceration occurrence and development.
In the relevant technologies, to study oral submucosa fibrosis, need to carry out oral submucosa fibrosis experiment, simulate mouth
The effect of chamber chewing betel nut, and prepare rat oral submucosa fibrosis experimental model, make model generally using syringe with
The mode that brushing tool is combined after rat anesthesia, opens rat oral cavity with haemostatic clamp and tweezers, fully exposes buccal mucosa, pay attention to from
Bicker, which is stretched at cheek, has body wrinkle to connect with buccal mucosa, and from joint, inserting needle enters under mucous membrane, after promoting 0.5cm inwardly, injection
0.2ml aqueous areca nut extracts (ANE) make mucous membrane protrusion in skin mound sample, then fine under the preparation rat mucous membrane of mouth of ANE with being moistened with again
The brush of dimensionization experimental model up and down, front and rear each brush 20 times.However, the mode that this kind of syringe is combined with brushing tool, needs anti-
Multiple injection and brush dip in so that experimental implementation is excessively complicated, waste of manpower, expends experimenter's plenty of time.
Therefore, it is necessary to it is above-mentioned to provide a kind of brush solution of new preparation rat oral submucosa fibrosis experimental model
Technical problem.
Invention content
The main object of the present invention is to provide a kind of brush for preparing rat oral submucosa fibrosis experimental model, it is intended to
The preparation rat oral submucosa fibrosis experimental model solved in the relevant technologies is inconvenient, and excessively labor intensive and time
The technical issues of cost.
To achieve the above object, the brush packet proposed by the present invention for preparing rat oral submucosa fibrosis experimental model
It includes：Brush holder is formed with liquid storage cavity in the brush holder, and the liquid storage cavity memory contains aqueous areca nut extract；Guide rail, the guide rail
Set on one end of the brush holder；Brush head, the brush head are slidably connected with the guide rail；More first bristles, first bristle
Set on the brush head；Woven hose, one end of the woven hose are connected with the liquid storage cavity, the other end of the woven hose and institute
State the connection of the first bristle；Partition board, the partition board are fixedly arranged in the brush holder；Elastic component, brush described in the elastic component elastic connection
Head and the partition board；Drive rod, one end of the drive rod are abutted with the brush head, and the other end of the drive rod stretches into described
Liquid storage cavity；Accelerator rod, the accelerator rod extend, and stretch into the woven hose from the other end bending of the drive rod.
Preferably, the brush for preparing rat oral submucosa fibrosis experimental model further includes tube assembly, the pipe
The other end of the brush holder is run through in one end of component, and is connected with the liquid storage cavity.
Preferably, the brush for preparing rat oral submucosa fibrosis experimental model further includes the first idler wheel, first
Gear, the first connecting shaft, the first rack and draining plate, first idler wheel are set on the brush holder, and the first gear is set on institute
State in liquid storage cavity, first connecting shaft run through the brush holder, and the first gear pass through with first idler wheel it is described
First connecting shaft is rotatablely connected, and first rack is meshed with the first gear, and first rack is towards the pipe group
One end of part is equipped with the draining plate.
Preferably, the brush for preparing rat oral submucosa fibrosis experimental model further includes the second idler wheel, second
Gear, the second connecting shaft and the second rack, second idler wheel are set on the brush holder, and the second gear is set on the woven hose
Interior, second connecting shaft runs through the brush holder, and second idler wheel passes through second connecting shaft with the second gear
Rotation connection, one end and the accelerator rod of second rack abut against, the other end and the brush holder of second rack
Between there are preset spacing.
Preferably, the accelerator rod, which further includes, cuts somebody's hair, and one end and described cut somebody's hair of second rack abut against.
Preferably, the brush for preparing rat oral submucosa fibrosis experimental model further includes more second bristles,
Second bristle is set on the brush head, and second bristle is in tip-like away from one end of the brush head.
Preferably, the one end of the woven hose far from the liquid storage cavity is formed with liquid drain hole, the preparation rat oral cavity
The brush of fibrosis experimental model further includes transparent liquid pad under mucous membrane, and the transparent liquid pad is set in the brush holder, and connects institute
State the first bristle and the liquid drain hole.
Preferably, the brush for preparing rat oral submucosa fibrosis experimental model further includes closed plate, the envelope
Closing plate is inserted into the brush holder, and the closed plate covers the transparent liquid pad.
Preferably, the drive rod passes through the elastic component, and through the partition board.
Preferably, the brush for preparing rat oral submucosa fibrosis experimental model further includes sleeve, the sleeve
It is set around the drive rod.
In the brush proposed by the present invention for preparing rat oral submucosa fibrosis experimental model, the liquid storage cavity memory
Aqueous areca nut extract is contained, one end of the woven hose is connected with the liquid storage cavity, the other end of the woven hose and described the
One bristle connects.When rat oral submucosa fibrosis experimental model starts from, first by rat anesthesia, then with haemostatic clamp and tweezer
Son opens rat oral cavity, is directly rubbed by the first bristle of the brush for preparing rat oral submucosa fibrosis experimental model big
The mucous membrane of mouth of mouse, the aqueous areca nut extract in liquid storage cavity flow into first bristle from the liquid-transport pipe-line, finally reach big
The mucous membrane of mouth of mouse, during the first bristle is contacted with the mucous membrane of mouth of rat, brush head moves along the rail therewith, drive rod
And the accelerator rod coordinated movement of various economic factors, accelerator rod can speed up the flowing for pushing aqueous areca nut extract, elastic component is effective right in the process
Brush head limit and reset, so as to fulfill rat oral submucosa fibrosis experimental model is easily prepared, with traditional injection and
Brush, which dips in, to be compared, and the brush simple operation of the preparation rat oral submucosa fibrosis experimental model, simulation works well, and is saved
The a large amount of human cost of experimenter and time cost.
Description of the drawings
In order to illustrate more clearly about the embodiment of the present invention or technical scheme of the prior art, to embodiment or will show below
There is attached drawing needed in technology description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this
Some embodiments of invention, for those of ordinary skill in the art, without creative efforts, can be with
Structure according to these attached drawings obtains other attached drawings.
Fig. 1 is the first embodiment of the brush provided by the invention for preparing rat oral submucosa fibrosis experimental model
Structure diagram；
Fig. 2 is the sectional view of the brush shown in FIG. 1 for preparing rat oral submucosa fibrosis experimental model；
Fig. 3 is the second embodiment of the brush provided by the invention for preparing rat oral submucosa fibrosis experimental model
Structure diagram；
Fig. 4 is the sectional view of the brush shown in Fig. 3 for preparing rat oral submucosa fibrosis experimental model；
Fig. 5 is the 3rd embodiment of the brush provided by the invention for preparing rat oral submucosa fibrosis experimental model
Structure diagram；
Fig. 6 is the sectional view of the brush shown in fig. 5 for preparing rat oral submucosa fibrosis experimental model；
Fig. 7 is A portions shown in fig. 6 enlarged drawing；
Fig. 8 is the fourth embodiment of the brush provided by the invention for preparing rat oral submucosa fibrosis experimental model
Structure diagram；
Fig. 9 is the sectional view of the brush shown in Fig. 8 for preparing rat oral submucosa fibrosis experimental model；
Figure 10 is B portions shown in Fig. 9 enlarged drawing.
The embodiments will be further described with reference to the accompanying drawings for the realization, the function and the advantages of the object of the present invention.
Specific embodiment
Below in conjunction with the attached drawing in the embodiment of the present invention, the technical solution in the embodiment of the present invention is carried out clear, complete
Site preparation describes, it is clear that described embodiment is only the part of the embodiment of the present invention, instead of all the embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art obtained without creative efforts it is all its
His embodiment, shall fall within the protection scope of the present invention.
It is to be appreciated that the directional instruction (such as up, down, left, right, before and after ...) of institute is only used in the embodiment of the present invention
In explaining relative position relation, motion conditions under a certain particular pose (as shown in drawings) between each component etc., if should
When particular pose changes, then directionality instruction also correspondingly changes correspondingly.
In addition, in the present invention such as relating to the description of " first ", " second " etc. be only used for description purpose, and it is not intended that
Indicate or imply its relative importance or the implicit quantity for indicating indicated technical characteristic.Define as a result, " first ",
At least one this feature can be expressed or be implicitly included to the feature of " second ".In the description of the present invention, " multiple " contain
Justice is at least two, such as two, three etc., unless otherwise specifically defined.
In the present invention unless specifically defined or limited otherwise, term " connection ", " fixation " etc. should be interpreted broadly,
For example, " fixation " can be fixedly connected or be detachably connected or integral；Can be mechanical connection or
Electrical connection；It can be directly connected, can also be indirectly connected by intermediary, can be the connection inside two elements or two
The interaction relationship of a element, unless otherwise restricted clearly.It for the ordinary skill in the art, can basis
Concrete condition understands the concrete meaning of above-mentioned term in the present invention.
In addition, the technical solution between each embodiment of the present invention can be combined with each other, but must be general with this field
Logical technical staff can be implemented as basis, will be understood that when the combination appearance of technical solution is conflicting or can not realize this
The combination of technical solution is not present, also not the present invention claims protection domain within.
The present invention proposes a kind of brush for preparing rat oral submucosa fibrosis experimental model.
First embodiment
Fig. 1-2 is please referred to, in the first embodiment of the present invention, prepares rat oral submucosa fibrosis experiment mould
The brush 100 of type includes：
Brush holder 1 is formed with liquid storage cavity 2 in brush holder 1, and 2 memory of liquid storage cavity contains aqueous areca nut extract；
Guide rail 3, guide rail 3 are set on one end of brush holder 1；
Brush head 4, brush head 4 are slidably connected with guide rail 3；
More first bristles 5, the first bristle 5 are set on brush head 4；
Woven hose 6, one end of woven hose 6 are connected with liquid storage cavity 2, and the other end of woven hose 6 is connected with the first bristle 5.
Partition board 7, partition board 7 are fixedly arranged in brush holder 1；
Elastic component 8,8 elastic connection brush head 4 of elastic component and partition board 7；
Drive rod 9, one end of drive rod 9 are abutted with brush head 4, and the other end of drive rod 9 stretches into liquid storage cavity 2；
Accelerator rod 9a, accelerator rod 9a extend, and stretch into woven hose 6 from the other end bending of drive rod 9.
In the brush 100 proposed by the present invention for preparing rat oral submucosa fibrosis experimental model, 2 memory of liquid storage cavity
Aqueous areca nut extract is contained, one end of woven hose 6 is connected with liquid storage cavity 2, and the other end of woven hose 6 is connected with the first bristle 5.Greatly
When mouse oral submucosa fibrosis experimental model starts from, first by rat anesthesia, then with haemostatic clamp and tweezers rat mouthful is opened
Chamber is directly sticked by the oral cavity of the first bristle 5 friction rat for the brush for preparing rat oral submucosa fibrosis experimental model
Film, the aqueous areca nut extract in liquid storage cavity 2 flow into the first bristle 5 from woven hose 6, finally reach the mucous membrane of mouth of rat,
During first bristle 5 is contacted with the mucous membrane of mouth of rat, brush head 4 moves therewith along guide rail 3, drive rod 9 and accelerator rod 9a
The coordinated movement of various economic factors, accelerator rod 9a can speed up the flowing for pushing aqueous areca nut extract, and elastic component 8 is in the process effectively to brush head 4
Limiting and reset, so as to fulfill rat oral submucosa fibrosis experimental model is easily prepared, are dipped in traditional injection and brush
It compares, 100 simple operation of brush of the preparation rat oral submucosa fibrosis experimental model, simulation works well, and saves
The a large amount of human cost of experimenter and time cost.
The brush 100 for preparing rat oral submucosa fibrosis experimental model further includes tube assembly 9b, and the one of tube assembly 9b
The other end of brush holder 1 is run through at end, and is connected with liquid storage cavity 2, consequently facilitating the Bin in liquid storage cavity 2 is replenished in time in experimenter
Bulky extracting solution.In the present embodiment, tube assembly 9b includes one end of liquid-in pipe 91b and pipe lid 93b, liquid-in pipe 91b through brush holder 1
The other end, and connected with liquid storage cavity 2, pipe lid 93b and the other end of liquid-in pipe 91b are detachably connected.
Referring to Fig. 1, the extending direction of guide rail 3 is parallel with the extending direction of the central axes of brush holder 1, the length of guide rail 3
Degree is less than the length of brush holder 1, and the length of brush head 4 is less than the length of guide rail 3.First one end of bristle 5 far from brush head 4 is in circular arc
Shape.
Referring to Fig. 2, in the present embodiment, the both ends of partition board 7 are connected with brush holder 1.Drive rod 9 passes through elastic component
8, and through partition board 7.
In the present embodiment, the quantity of elastic component 8 is one, it is possible to understand that in other embodiments, the quantity of elastic component 8 can
Think multiple, it is only necessary to meet elastic connection brush head 4 and partition board 7.As a kind of preferred mode of the present embodiment, elastic component
8 be spring.
One end of the separate liquid storage cavity 2 of woven hose 6 is formed with liquid drain hole 61, and it is real to prepare rat oral submucosa fibrosis
The brush for testing model further includes transparent liquid pad 9n, and transparent liquid pad 9n is set in brush holder 1, and connects the first bristle 5 and liquid drain hole 61.
So as to which effectively buffering aqueous areca nut extract enters the first bristle 5.In the present embodiment, woven hose 6 runs through partition board 7, transparent liquid pad 9n
It can be sponge.
The brush 100 for preparing rat oral submucosa fibrosis experimental model further includes closed plate 9p, and closed plate 9p is inserted into
Brush holder 1, and closed plate 9p covering transparent liquid pad 9n, consequently facilitating experimenter blocks transparent liquid pad 9n, control aqueous areca nut extract
Random output.In the present embodiment, closed plate 9p is detachably connected with brush holder 1, it is possible to understand that in other embodiments, closed plate
9p can be hinged with brush holder 1.
Further, the area equation of transparent liquid pad 9n and closed plate 9p.Prepare the experiment of rat oral submucosa fibrosis
The brush 100 of model further includes sleeve 9q, and sleeve 9q is set around drive rod 9, consequently facilitating the movement of specification drive rod 9, is protected
Demonstrate,prove the movement of its stabilization.
Second embodiment
Fig. 3-4 are please referred to, it is real based on the preparation rat oral submucosa fibrosis in the first embodiment of the present invention
Test the brush 100 of model, in second embodiment, the brush 200 for preparing rat oral submucosa fibrosis experimental model further includes
First idler wheel 9c, first gear 9d, the first connecting shaft 9e, the first rack 9f and draining plate 9g, the first idler wheel 9c are set on brush holder 1,
First gear 9d is set in liquid storage cavity 2, and the first connecting shaft 9e runs through brush holder 1, and first gear 9d and the first idler wheel 9c passes through
First connecting shaft 9e is rotatablely connected, and the first rack 9f is meshed with first gear 9d, and the first rack 9f is towards the one of tube assembly 9b
End is equipped with draining plate 9g.
The use principle of the brush 200 of the preparation rat oral submucosa fibrosis experimental model of the present embodiment is as follows：
By the rotation of the first idler wheel 9c, the rotation of first gear 9d is driven, the rotation of first gear 9d can drive the
The movement of one rack 9f, referring to Fig. 4, when the first idler wheel 9c is rotated clockwise, first gear 9d is rotated clockwise therewith, the
One rack 9f drives draining plate 9g close to tube assembly 9b, so as to which barrier aqueous areca nut extract rapidly enters liquid storage cylinder from tube assembly 9b
Body avoids betel nut from shifting to an earlier date liquid and quickly flows out the brush for preparing rat oral submucosa fibrosis experimental model.As the first idler wheel 9c
When rotating counterclockwise, first gear 9d is rotated counterclockwise therewith, and the first rack 9f is close to accelerator rod 9a, until being supported with accelerator rod 9a
It connects, so as to limit displacements of the accelerator rod 9a in liquid storage cylinder body and in woven hose 6, by controlling the displacement of accelerator rod 9a,
Control the output speed of aqueous areca nut extract.
3rd embodiment
Fig. 5-7 are please referred to, mould is tested based on rat oral submucosa fibrosis is prepared in second embodiment of the invention
The brush 200 of type, in 3rd embodiment, the brush 300 for preparing rat oral submucosa fibrosis experimental model further includes the
Second wheel 9h, second gear 9i, the second connecting shaft 9j and the second rack 9k, the second idler wheel 9h are set on brush holder 1, and second gear 9i is set
In in woven hose 6, the second connecting shaft 9j runs through brush holder 1, and the second idler wheel 9h and second gear 9i is turned by the second connecting shaft 9j
Dynamic connection, one end and the accelerator rod 9a of the second rack 9k are abutted against, and are existed between the other end of the second rack 9k and brush holder 1 default
Spacing.
As a kind of preferred mode of the present embodiment, accelerator rod 9a further includes the 91a that cuts somebody's hair, one end of the second rack 9k with
The 91a that cuts somebody's hair is abutted against.
The use principle of the brush 300 of the preparation rat oral submucosa fibrosis experimental model of the present embodiment is as follows：
By the rotation of the second idler wheel 9h, the rotation of second gear 9i is driven, the rotation of first gear 9d can drive the
The movement of two rack 9k, please gather refering to Fig. 6 and Fig. 7, when the second idler wheel 9h is rotated clockwise, second gear 9i up times therewith
Needle rotates, and the second rack 9k is close to accelerator rod 9a, until being abutted with accelerator rod 9a, so as to limit accelerator rod 9a in woven hose 6
Displacement, by controlling the displacement of accelerator rod 9a, control the output speed of aqueous areca nut extract.
When the first idler wheel 9c is rotated counterclockwise, second gear 9i is rotated counterclockwise therewith, and the second rack 9k is far from acceleration
Bar 9a, so as to provide space in woven hose 6 for accelerator rod 9a.
Further, when the second idler wheel 9h is rotated clockwise, the first idler wheel 9c is rotated counterclockwise, and can realize the second rack
9k and the first rack 9f clamping accelerator rod 9a, and thoroughly lock the movement of accelerator rod 9a so that brush head 4 can not be transported along sliding rail
It is dynamic, it is fixed value by the control of aqueous areca nut extract output speed.
Fourth embodiment
Fig. 8-10 are please referred to, the preparation rat oral submucosa fibrosis experimental model proposed based on 3rd embodiment
Brush 300, in fourth embodiment, the brush 400 for preparing rat oral submucosa fibrosis experimental model further includes more the
Two bristle 9m, the second bristle 9m is set on brush head 4, and the second bristle 9m is in tip-like away from one end of brush head 4, is prepared so as to be promoted
The brush 400 of rat oral submucosa fibrosis experimental model advanced optimizes to the mechanical wear in rat oral cavity and prepares rat
The brush 400 of oral submucosa fibrosis experimental model chews oral cavity the simulation effect of betel nut.One kind as the present embodiment is excellent
The mode of choosing, every second bristle 9m are set between two the first adjacent bristles 5.
Referring to Fig. 9, in the present embodiment, prepare the brush 400 of rat oral submucosa fibrosis experimental model with
3rd embodiment propose preparation rat oral submucosa fibrosis experimental model brush 300 the difference lies in：
Tube assembly 9b further includes auxiliary tube 92b, and auxiliary tube 92b bends extension from liquid-in pipe 91b along the direction far from brush head 4
It forms, pipe lid 93b is detachably connected with auxiliary tube 92b, consequently facilitating betel nut is replenished in time in experimenter during experiment
Extracting solution is avoided because the deficiency of aqueous areca nut extract causes the unnecessary suspension of experiment.It these are only the preferred implementation of the present invention
Example, is not intended to limit the scope of the invention, every under the design of the present invention, using in description of the invention and attached drawing
Hold made equivalent structure transformation or direct/indirect patent for being used in other related technical areas and being included in the present invention
In protection domain.
Claims (10)
1. a kind of brush for preparing rat oral submucosa fibrosis experimental model, which is characterized in that including：
Brush holder is formed with liquid storage cavity in the brush holder, and the liquid storage cavity memory contains aqueous areca nut extract；
Guide rail, the guide rail are set on one end of the brush holder；
Brush head, the brush head are slidably connected with the guide rail；
More first bristles, first bristle are set on the brush head；
Woven hose, one end of the woven hose are connected with the liquid storage cavity, the other end of the woven hose and the described first brush
Hair connection.
Partition board, the partition board are fixedly arranged in the brush holder；
Elastic component, brush head described in the elastic component elastic connection and the partition board；
Drive rod, one end of the drive rod are abutted with the brush head, and the other end of the drive rod stretches into the liquid storage cavity；
Accelerator rod, the accelerator rod extend, and stretch into the woven hose from the other end bending of the drive rod.
2. the brush of rat oral submucosa fibrosis experimental model is prepared as described in claim 1, which is characterized in that described
The brush for preparing rat oral submucosa fibrosis experimental model further includes tube assembly, and the brush is run through in one end of the tube assembly
The other end of handle, and connected with the liquid storage cavity.
3. the brush of rat oral submucosa fibrosis experimental model is prepared as claimed in claim 2, which is characterized in that described
The brush for preparing rat oral submucosa fibrosis experimental model further includes the first idler wheel, first gear, the first connecting shaft, first
Rack and draining plate, first idler wheel are set on the brush holder, and the first gear is set in the liquid storage cavity, and described first
Connecting shaft runs through the brush holder, and the first gear is rotatablely connected with first idler wheel by first connecting shaft, institute
It states the first rack to be meshed with the first gear, first rack is equipped with the drain towards one end of the tube assembly
Plate.
4. the brush of rat oral submucosa fibrosis experimental model is prepared as claimed in claim 3, which is characterized in that described
The brush for preparing rat oral submucosa fibrosis experimental model further includes the second idler wheel, second gear, the second connecting shaft and the
Two racks, second idler wheel are set on the brush holder, and the second gear is set in the woven hose, and second connecting shaft is passed through
The brush holder is worn, and second idler wheel is rotatablely connected with the second gear by second connecting shaft, second tooth
One end of item is abutted against with the accelerator rod, and there are preset spacing between the other end and the brush holder of second rack.
5. the brush of rat oral submucosa fibrosis experimental model is prepared as claimed in claim 4, which is characterized in that described
Accelerator rod, which further includes, cuts somebody's hair, and one end and described cut somebody's hair of second rack abut against.
6. the brush of rat oral submucosa fibrosis experimental model is prepared as claimed in claim 4, which is characterized in that described
The brush for preparing rat oral submucosa fibrosis experimental model further includes more second bristles, and second bristle is set on described
Brush head, and second bristle is in tip-like away from one end of the brush head.
7. the brush of rat oral submucosa fibrosis experimental model is prepared as described in claim 1, which is characterized in that described
One end far from the liquid storage cavity of woven hose is formed with liquid drain hole, the preparation rat oral submucosa fibrosis experiment mould
The brush of type further includes transparent liquid pad, and the transparent liquid pad is set in the brush holder, and connect first bristle with it is described
Fluid apertures.
8. the brush of rat oral submucosa fibrosis experimental model is prepared as claimed in claim 7, which is characterized in that described
The brush for preparing rat oral submucosa fibrosis experimental model further includes closed plate, and the closed plate is inserted into the brush holder, and
The closed plate covers the transparent liquid pad.
9. the brush of the preparation rat oral submucosa fibrosis experimental model as described in any one of claim 1-8, special
Sign is that the drive rod passes through the elastic component, and through the partition board.
10. the brush of the preparation rat oral submucosa fibrosis experimental model as described in any one of claim 1-8, special
Sign is that the brush for preparing rat oral submucosa fibrosis experimental model further includes sleeve, and the sleeve is around described
Drive rod is set.
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| CN201810062043.0A CN108236198B (en) | 2018-01-23 | 2018-01-23 | Brush for preparing rat oral submucosal fibrosis experimental model |
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| CN201810062043.0A CN108236198B (en) | 2018-01-23 | 2018-01-23 | Brush for preparing rat oral submucosal fibrosis experimental model |
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| CN108236198A true CN108236198A (en) | 2018-07-03 |
| CN108236198B CN108236198B (en) | 2021-04-02 |
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Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2426302Y (en) * | 2000-04-19 | 2001-04-11 | 许修海 | Brush with liquid in it |
| CN2623163Y (en) * | 2003-04-18 | 2004-07-07 | 耿显福 | Shoe brush with automatic shoe-polish distribution device |
| CN202233746U (en) * | 2011-09-15 | 2012-05-30 | 淄博职业学院 | Toothbrush with changeable toothbrush head |
| CN102614494A (en) * | 2012-04-26 | 2012-08-01 | 中南大学 | Oral submucous fibrosis rat model construction method |
| CN202950194U (en) * | 2012-12-05 | 2013-05-29 | 陈海龙 | Novel oral cleaner |
| CN204161988U (en) * | 2014-09-30 | 2015-02-18 | 太西煤集团阿克塞汇丰矿物开发有限责任公司 | A kind of helix transporting device for Separation of Solid and Liquid |
| CN106535698A (en) * | 2014-07-15 | 2017-03-22 | 欧莱雅公司 | Cosmetic formulation dispensing head for personal care appliance |
| CN106511345A (en) * | 2016-09-21 | 2017-03-22 | 海南省人民医院 | Construction method of oral submucous fibrosis mouse model |
| CN106859796A (en) * | 2017-02-24 | 2017-06-20 | 榆林学院 | A kind of electric toothbrush with brush of doing more physical exercises |
-
2018
- 2018-01-23 CN CN201810062043.0A patent/CN108236198B/en active Active
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2426302Y (en) * | 2000-04-19 | 2001-04-11 | 许修海 | Brush with liquid in it |
| CN2623163Y (en) * | 2003-04-18 | 2004-07-07 | 耿显福 | Shoe brush with automatic shoe-polish distribution device |
| CN202233746U (en) * | 2011-09-15 | 2012-05-30 | 淄博职业学院 | Toothbrush with changeable toothbrush head |
| CN102614494A (en) * | 2012-04-26 | 2012-08-01 | 中南大学 | Oral submucous fibrosis rat model construction method |
| CN202950194U (en) * | 2012-12-05 | 2013-05-29 | 陈海龙 | Novel oral cleaner |
| CN106535698A (en) * | 2014-07-15 | 2017-03-22 | 欧莱雅公司 | Cosmetic formulation dispensing head for personal care appliance |
| CN204161988U (en) * | 2014-09-30 | 2015-02-18 | 太西煤集团阿克塞汇丰矿物开发有限责任公司 | A kind of helix transporting device for Separation of Solid and Liquid |
| CN106511345A (en) * | 2016-09-21 | 2017-03-22 | 海南省人民医院 | Construction method of oral submucous fibrosis mouse model |
| CN106859796A (en) * | 2017-02-24 | 2017-06-20 | 榆林学院 | A kind of electric toothbrush with brush of doing more physical exercises |
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|---|---|
| CN108236198B (en) | 2021-04-02 |
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