CN108215025A - A kind of device for being used to prepare lacrimal bolt - Google Patents

A kind of device for being used to prepare lacrimal bolt Download PDF

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Publication number
CN108215025A
CN108215025A CN201810192899.XA CN201810192899A CN108215025A CN 108215025 A CN108215025 A CN 108215025A CN 201810192899 A CN201810192899 A CN 201810192899A CN 108215025 A CN108215025 A CN 108215025A
Authority
CN
China
Prior art keywords
formed pipe
tube socket
prepare
molding tube
lacrimal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810192899.XA
Other languages
Chinese (zh)
Inventor
李锐聪
杨习锋
曾晨光
郭少成
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangzhou Ruicheng Medical Technology Co ltd
Original Assignee
Guangzhou Sun Shing Biotech Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangzhou Sun Shing Biotech Co ltd filed Critical Guangzhou Sun Shing Biotech Co ltd
Priority to CN201810192899.XA priority Critical patent/CN108215025A/en
Publication of CN108215025A publication Critical patent/CN108215025A/en
Pending legal-status Critical Current

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/02Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/22Component parts, details or accessories; Auxiliary operations
    • B29C39/26Moulds or cores
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001Designing or manufacturing processes
    • A61F2240/002Designing or making customized prostheses

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

The invention discloses a kind of devices for being used to prepare lacrimal bolt, which is characterized in that including:Pedestal, the pedestal include bottom plate and side plate, and the side plate is connect with the bottom plate;Tube socket is molded, the molding tube socket is set to the upper surface of the bottom plate;The molding tube socket is equipped with accommodating chamber;The top of the formed pipe is provided with guide surface;Formed pipe, the formed pipe are correspondingly arranged with the molding tube socket, and the formed pipe is detachably arranged in the accommodating chamber;The formed pipe is the transparent hollow tube of both ends open.Provided by the present invention for preparing the device of lacrimal bolt, it is suitable for preparing lacrimal bolt by raw material of pHEMA, convenient for pHEMA gel formings, and it can prepare multiple lacrimal bolts simultaneously, greatly improve work efficiency;Simultaneously as it uses transparent formed pipe to be molded, convenient for introducing ultraviolet light cross-linking in preparation process.

Description

A kind of device for being used to prepare lacrimal bolt
Technical field
The present invention relates to a kind of devices for being used to prepare lacrimal bolt.
Background technology
Dry eyes, also known as cornea and conjunctiva xerosis refer to since the exception or tear fluid dynamics of tear quality and quantity are abnormal Caused tear film is unstable and ocular surface injury, so as to cause a kind of disease of ophthalmic uncomfortable symptom.Tear is carried out using various emboluses Tubule embolism is a kind of newer lacrimal passage sealing technique, by mechanical obstruction lacrimal passage, reduces the discharge of tear, re-establishes The balance of ocular tear improves ocular environment, so as to the sings and symptoms of substantially reduced patient's dry eyes.
At present, the most commonly used embolism materials are silicon rubber or polyurethane, however the two mechanical strength and tissue phase Difference is larger, while lacks bioactivity, and patient's implant site foreign body sensation is easily caused after implantation;And material is planted in hydrophobicity It is fashionable to be assisted with lubricating oil, and be implanted into the period be usually no more than one month, therefore it is overdue need replacing, carry out second operation take Phenomena such as going out, often generate secondary damage, leading to the reactions such as bleeding, inflammation, and then granulation hyperplasia occurs, is not suitable as implantation material It implants.
Applicant has found in the course of the research, pHEMA hydrogel material good biocompatibilities, with tissue mechanical strength Quite, compliance is good after implanting, and greatly reduces the foreign body sensation of implant site;And the hydrogel can absorb water from swollen It is swollen, there is good self-retaining effect, be suitble to be chronically implanted.However silicon rubber or polyurethane are mainly processed by extrusion way Type is not suitable for the molding of pHEMA gels.And there is partial gel to need uv-light polymerization aftershaping in gel embolism, tradition Extrusion way can not more realize.
Therefore, how to propose it is a kind of be suitable for use pHEMA hydrogel materials to prepare the device of lacrimal bolt, make it just In pHEMA gel formings, polymerization forming is carried out convenient for introducing ultraviolet light in the fabrication process, it appears particularly important.
Invention content
In view of the shortcomings of the prior art, the object of the present invention is to provide a kind of devices for being used to prepare lacrimal bolt, fit For preparing lacrimal bolt by raw material of pHEMA, convenient for pHEMA gel formings, and it can prepare multiple lacrimals simultaneously Bolt greatly improves work efficiency;Simultaneously as it uses transparent formed pipe to be molded, it is purple convenient for being introduced in preparation process Outer photo-crosslinking.
To achieve the above object, the present invention provides a kind of device for being used to prepare lacrimal bolt, including:
Pedestal, the pedestal include bottom plate and side plate, and the side plate is connect with the bottom plate.
Tube socket is molded, the molding tube socket is set to the upper surface of the bottom plate;The molding tube socket is equipped with accommodating chamber; The top of the formed pipe is provided with guide surface.
Formed pipe, the formed pipe are correspondingly arranged with the molding tube socket, and the formed pipe is detachably arranged in described In accommodating chamber;The formed pipe is the transparent hollow tube of both ends open.
In the present invention, molding tube socket is for fixed-type pipe, so as to which in the feeding into formed pipe, formed pipe will not shake It is dynamic, convenient for pHEMA gel formings.
In the present invention, guide surface is set on the top of molding tube socket, convenient for formed pipe is insert molded in tube socket.
In the present invention, formed pipe is used for pHEMA gel formings.Its both ends open, for inject pHEMA raw materials and Lacrimal bolt product is taken out after pHEMA gel formings.It can be polyethylene, polyformaldehyde, polyurethane or glass with transparent hollow pipe Transparent pipe made of glass, convenient for introducing ultraviolet connection.
Compared with prior art, the device disclosed by the invention for being used to prepare lacrimal bolt, by being arranged on pedestal Type tube socket carrys out fixed-type pipe;The lumen convenient for pHEMA gel formings is provided by formed pipe;It is disclosed by the invention to be used to prepare The device of lacrimal bolt it is suitable for preparing lacrimal bolt by raw material of pHEMA, is convenient for pHEMA gel formings;Meanwhile Since it uses transparent formed pipe to be molded, convenient for introducing ultraviolet light cross-linking in preparation process.
According to another specific embodiment of the present invention, the guide surface is the conical surface.
According to another specific embodiment of the present invention, several molding tube sockets are provided on the bottom plate, it is several described Molding tube socket is arranged in array.
In the present invention, since formed pipe and molding tube socket are correspondingly arranged, then the number of formed pipe is also multiple, and each Being molded setting in tube socket, there are one formed pipes
In the present invention, by setting the molding tube socket being arranged in array;Multiple gel tubes can be prepared simultaneously, greatly improved Working efficiency.
According to another specific embodiment of the present invention, the molding tube socket is hollow tubular.
According to another specific embodiment of the present invention, reinforcing rib is further provided on the bottom plate, the reinforcing rib is located at The lower surface of the bottom plate.
According to another specific embodiment of the present invention, the number of the reinforcing rib is 2, and 2 reinforcing ribs are parallel to be set It puts.
According to another specific embodiment of the present invention, the length and the length ratio of the formed pipe of the molding tube socket are 1:4.
According to another specific embodiment of the present invention, the internal diameter of the molding tube socket for 0.5 ± 0.05mm-2 ± 0.05mm;The outer diameter of the molding tube socket is 1 ± 0.05mm-3 ± 0.05mm.
According to another specific embodiment of the present invention, the length of the molding tube socket is 3 ± 0.5mm-8 ± 0.5mm.
According to another specific embodiment of the present invention, the outer diameter of the formed pipe is 0.5 ± 0.05mm-2 ± 0.05mm; The internal diameter of the formed pipe is 0.5 ± 0.05mm-1.5 ± 0.05mm.
The application method of device provided by the present invention for preparing lacrimal bolt is:
1st, from the pHEMA starting material solutions of the top of formed pipe injection premix, until liquid level is concordant with formed pipe top.
2nd, the device certain time is stood, reaction solution molding to be premixed obtains lacrimal bolt.
3rd, formed pipe is taken out, and then takes out the lacrimal bolt in formed pipe.
Below in conjunction with the attached drawing in the embodiment of the present invention, the technical solution in the embodiment of the present invention is carried out clear, complete Site preparation describes, it is clear that described embodiment is only part of the embodiment of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, those of ordinary skill in the art are obtained every other without creative efforts Embodiment shall fall within the protection scope of the present invention.
Description of the drawings
Fig. 1 is the structure diagram for the device for being used to prepare lacrimal bolt that embodiment 1 provides.
Specific embodiment
Embodiment 1
It is the structure diagram of the device provided in this embodiment for being used to prepare lacrimal bolt referring to Fig. 1.The device packet It includes:Pedestal 1, molding tube socket 2 and formed pipe 3.
Wherein:Pedestal 1 includes bottom plate 11 and side plate 12, and the side plate 12 is connect with the bottom plate 11;, the following table of bottom plate 11 Face is equipped with reinforcing rib (not shown), and the number of reinforcing rib is 2, and 2 reinforcing ribs are arranged in parallel.
Molding tube socket 2 is set to the upper surface of the bottom plate 11;The molding tube socket is equipped with accommodating chamber;The formed pipe 2 top is provided with guide surface 21.
In the present embodiment, molding tube socket 2 is hollow tubular.
In the present embodiment, molding tube socket 2 has two rows, per 5 molding tube sockets 2 of behavior.
In the present embodiment, guide surface 21 is the conical surface.
Formed pipe 3 is correspondingly arranged with the molding tube socket 2, and the formed pipe 3 is detachably arranged in the accommodating chamber; The formed pipe 3 is the transparent hollow tube of both ends open.
In the present embodiment, it is 1 to be molded the length of tube socket 3 with the length ratio of formed pipe 3:4.
In the present embodiment, accordingly, formed pipe 3 is two rows, per five formed pipes 3 of behavior.
Provided by the present invention for preparing the device of lacrimal bolt, it is suitable for preparing lacrimal by raw material of pHEMA Bolt, convenient for pHEMA gel formings, and it can prepare multiple lacrimal bolts simultaneously, greatly improve work efficiency;Meanwhile by Transparent formed pipe is used to be molded in it, convenient for introducing ultraviolet light cross-linking in preparation process.
Although the present invention is disclosed above with preferred embodiment, it is not limited to the range that the present invention is implemented.Any The those of ordinary skill in field in the invention scope for not departing from the present invention, improves when can make a little, i.e., every according to this hair Bright done equal improvement, should be the scope of the present invention and is covered.

Claims (10)

1. a kind of device for being used to prepare lacrimal bolt, which is characterized in that including:
Pedestal, the pedestal include bottom plate and side plate, and the side plate is connect with the bottom plate;
Tube socket is molded, the molding tube socket is set to the upper surface of the bottom plate;The molding tube socket is equipped with accommodating chamber;It is described The top of formed pipe is provided with guide surface;
Formed pipe, the formed pipe are correspondingly arranged with the molding tube socket, and the formed pipe is detachably arranged in the receiving Intracavitary;The formed pipe is the transparent hollow tube of both ends open.
2. the device as described in claim 1 for being used to prepare lacrimal bolt, which is characterized in that the guide surface is the conical surface.
3. the device as described in claim 1 for being used to prepare lacrimal bolt, which is characterized in that be provided on the bottom plate several The molding tube socket, several molding tube sockets are arranged in array.
4. the device as described in claim 1 for being used to prepare lacrimal bolt, which is characterized in that the molding tube socket is hollow tube Shape.
5. the device as described in claim 1 for being used to prepare lacrimal bolt, which is characterized in that be further provided on the bottom plate Reinforcing rib, the reinforcing rib are located at the lower surface of the bottom plate.
6. the device as claimed in claim 5 for being used to prepare lacrimal bolt, which is characterized in that the number of the reinforcing rib is 2 A, 2 reinforcing ribs are arranged in parallel.
7. the as claimed in claim 4 device for being used to prepare lacrimal bolt, which is characterized in that the length of the molding tube socket with The length ratio of the formed pipe is 1:4.
8. the as claimed in claim 4 device for being used to prepare lacrimal bolt, which is characterized in that the internal diameter of the molding tube socket is 0.5 ± 0.05mm-2 ± 0.05mm;The outer diameter of the molding tube socket is 1 ± 0.05mm-3 ± 0.05mm.
9. the as claimed in claim 4 device for being used to prepare lacrimal bolt, which is characterized in that the length of the molding tube socket is 3 ± 0.5mm-8 ± 0.5mm.
10. the as described in claim 1 device for being used to prepare lacrimal bolt, which is characterized in that the outer diameter of the formed pipe is 0.5 ± 0.05mm-2 ± 0.05mm;The internal diameter of the formed pipe is 0.5 ± 0.05mm-1.5 ± 0.05mm.
CN201810192899.XA 2018-03-08 2018-03-08 A kind of device for being used to prepare lacrimal bolt Pending CN108215025A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810192899.XA CN108215025A (en) 2018-03-08 2018-03-08 A kind of device for being used to prepare lacrimal bolt

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810192899.XA CN108215025A (en) 2018-03-08 2018-03-08 A kind of device for being used to prepare lacrimal bolt

Publications (1)

Publication Number Publication Date
CN108215025A true CN108215025A (en) 2018-06-29

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ID=62658208

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810192899.XA Pending CN108215025A (en) 2018-03-08 2018-03-08 A kind of device for being used to prepare lacrimal bolt

Country Status (1)

Country Link
CN (1) CN108215025A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110269742A (en) * 2019-05-28 2019-09-24 广州新诚生物科技有限公司 A kind of preparation method of hollow hydrogel Punctal plug

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106496601A (en) * 2016-10-26 2017-03-15 华南理工大学 A kind of can be from the high intensity hydrogel and preparation method thereof into tubulose or cup-shaped
CN107756700A (en) * 2017-10-30 2018-03-06 广州新诚生物科技有限公司 A kind of device for being used to prepare gel tube
CN208006096U (en) * 2018-03-08 2018-10-26 广州新诚生物科技有限公司 A kind of device being used to prepare lacrimal bolt

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106496601A (en) * 2016-10-26 2017-03-15 华南理工大学 A kind of can be from the high intensity hydrogel and preparation method thereof into tubulose or cup-shaped
CN107756700A (en) * 2017-10-30 2018-03-06 广州新诚生物科技有限公司 A kind of device for being used to prepare gel tube
CN208006096U (en) * 2018-03-08 2018-10-26 广州新诚生物科技有限公司 A kind of device being used to prepare lacrimal bolt

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110269742A (en) * 2019-05-28 2019-09-24 广州新诚生物科技有限公司 A kind of preparation method of hollow hydrogel Punctal plug

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Effective date of registration: 20200605

Address after: 510000 Guangdong international Guangzhou Biological Island three spiral Road 6, seventh, 701 units (self declaration)

Applicant after: GUANGZHOU RUICHENG MEDICAL TECHNOLOGY Co.,Ltd.

Address before: 510200, 6, seventh, 701, spiral three, International Biological Island, Guangdong, Guangzhou

Applicant before: GUANGZHOU SUN-SHING BIOTECH Co.,Ltd.

TA01 Transfer of patent application right
TA01 Transfer of patent application right

Effective date of registration: 20200619

Address after: 510000 Guangdong international Guangzhou Biological Island three spiral Road 6, seventh, 701 units (self declaration)

Applicant after: GUANGZHOU RUICHENG MEDICAL TECHNOLOGY Co.,Ltd.

Address before: 510200, 6, seventh, 701, spiral three, International Biological Island, Guangdong, Guangzhou

Applicant before: GUANGZHOU SUN-SHING BIOTECH Co.,Ltd.

TA01 Transfer of patent application right