Background technology
Dry eyes, also known as cornea and conjunctiva xerosis refer to since the exception or tear fluid dynamics of tear quality and quantity are abnormal
Caused tear film is unstable and ocular surface injury, so as to cause a kind of disease of ophthalmic uncomfortable symptom.Tear is carried out using various emboluses
Tubule embolism is a kind of newer lacrimal passage sealing technique, by mechanical obstruction lacrimal passage, reduces the discharge of tear, re-establishes
The balance of ocular tear improves ocular environment, so as to the sings and symptoms of substantially reduced patient's dry eyes.
At present, the most commonly used embolism materials are silicon rubber or polyurethane, however the two mechanical strength and tissue phase
Difference is larger, while lacks bioactivity, and patient's implant site foreign body sensation is easily caused after implantation;And material is planted in hydrophobicity
It is fashionable to be assisted with lubricating oil, and be implanted into the period be usually no more than one month, therefore it is overdue need replacing, carry out second operation take
Phenomena such as going out, often generate secondary damage, leading to the reactions such as bleeding, inflammation, and then granulation hyperplasia occurs, is not suitable as implantation material
It implants.
Applicant has found in the course of the research, pHEMA hydrogel material good biocompatibilities, with tissue mechanical strength
Quite, compliance is good after implanting, and greatly reduces the foreign body sensation of implant site;And the hydrogel can absorb water from swollen
It is swollen, there is good self-retaining effect, be suitble to be chronically implanted.However silicon rubber or polyurethane are mainly processed by extrusion way
Type is not suitable for the molding of pHEMA gels.And there is partial gel to need uv-light polymerization aftershaping in gel embolism, tradition
Extrusion way can not more realize.
Therefore, how to propose it is a kind of be suitable for use pHEMA hydrogel materials to prepare the device of lacrimal bolt, make it just
In pHEMA gel formings, polymerization forming is carried out convenient for introducing ultraviolet light in the fabrication process, it appears particularly important.
Invention content
In view of the shortcomings of the prior art, the object of the present invention is to provide a kind of devices for being used to prepare lacrimal bolt, fit
For preparing lacrimal bolt by raw material of pHEMA, convenient for pHEMA gel formings, and it can prepare multiple lacrimals simultaneously
Bolt greatly improves work efficiency;Simultaneously as it uses transparent formed pipe to be molded, it is purple convenient for being introduced in preparation process
Outer photo-crosslinking.
To achieve the above object, the present invention provides a kind of device for being used to prepare lacrimal bolt, including:
Pedestal, the pedestal include bottom plate and side plate, and the side plate is connect with the bottom plate.
Tube socket is molded, the molding tube socket is set to the upper surface of the bottom plate;The molding tube socket is equipped with accommodating chamber;
The top of the formed pipe is provided with guide surface.
Formed pipe, the formed pipe are correspondingly arranged with the molding tube socket, and the formed pipe is detachably arranged in described
In accommodating chamber;The formed pipe is the transparent hollow tube of both ends open.
In the present invention, molding tube socket is for fixed-type pipe, so as to which in the feeding into formed pipe, formed pipe will not shake
It is dynamic, convenient for pHEMA gel formings.
In the present invention, guide surface is set on the top of molding tube socket, convenient for formed pipe is insert molded in tube socket.
In the present invention, formed pipe is used for pHEMA gel formings.Its both ends open, for inject pHEMA raw materials and
Lacrimal bolt product is taken out after pHEMA gel formings.It can be polyethylene, polyformaldehyde, polyurethane or glass with transparent hollow pipe
Transparent pipe made of glass, convenient for introducing ultraviolet connection.
Compared with prior art, the device disclosed by the invention for being used to prepare lacrimal bolt, by being arranged on pedestal
Type tube socket carrys out fixed-type pipe;The lumen convenient for pHEMA gel formings is provided by formed pipe;It is disclosed by the invention to be used to prepare
The device of lacrimal bolt it is suitable for preparing lacrimal bolt by raw material of pHEMA, is convenient for pHEMA gel formings;Meanwhile
Since it uses transparent formed pipe to be molded, convenient for introducing ultraviolet light cross-linking in preparation process.
According to another specific embodiment of the present invention, the guide surface is the conical surface.
According to another specific embodiment of the present invention, several molding tube sockets are provided on the bottom plate, it is several described
Molding tube socket is arranged in array.
In the present invention, since formed pipe and molding tube socket are correspondingly arranged, then the number of formed pipe is also multiple, and each
Being molded setting in tube socket, there are one formed pipes
In the present invention, by setting the molding tube socket being arranged in array;Multiple gel tubes can be prepared simultaneously, greatly improved
Working efficiency.
According to another specific embodiment of the present invention, the molding tube socket is hollow tubular.
According to another specific embodiment of the present invention, reinforcing rib is further provided on the bottom plate, the reinforcing rib is located at
The lower surface of the bottom plate.
According to another specific embodiment of the present invention, the number of the reinforcing rib is 2, and 2 reinforcing ribs are parallel to be set
It puts.
According to another specific embodiment of the present invention, the length and the length ratio of the formed pipe of the molding tube socket are
1:4.
According to another specific embodiment of the present invention, the internal diameter of the molding tube socket for 0.5 ± 0.05mm-2 ±
0.05mm;The outer diameter of the molding tube socket is 1 ± 0.05mm-3 ± 0.05mm.
According to another specific embodiment of the present invention, the length of the molding tube socket is 3 ± 0.5mm-8 ± 0.5mm.
According to another specific embodiment of the present invention, the outer diameter of the formed pipe is 0.5 ± 0.05mm-2 ± 0.05mm;
The internal diameter of the formed pipe is 0.5 ± 0.05mm-1.5 ± 0.05mm.
The application method of device provided by the present invention for preparing lacrimal bolt is:
1st, from the pHEMA starting material solutions of the top of formed pipe injection premix, until liquid level is concordant with formed pipe top.
2nd, the device certain time is stood, reaction solution molding to be premixed obtains lacrimal bolt.
3rd, formed pipe is taken out, and then takes out the lacrimal bolt in formed pipe.
Below in conjunction with the attached drawing in the embodiment of the present invention, the technical solution in the embodiment of the present invention is carried out clear, complete
Site preparation describes, it is clear that described embodiment is only part of the embodiment of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, those of ordinary skill in the art are obtained every other without creative efforts
Embodiment shall fall within the protection scope of the present invention.
Embodiment 1
It is the structure diagram of the device provided in this embodiment for being used to prepare lacrimal bolt referring to Fig. 1.The device packet
It includes:Pedestal 1, molding tube socket 2 and formed pipe 3.
Wherein:Pedestal 1 includes bottom plate 11 and side plate 12, and the side plate 12 is connect with the bottom plate 11;, the following table of bottom plate 11
Face is equipped with reinforcing rib (not shown), and the number of reinforcing rib is 2, and 2 reinforcing ribs are arranged in parallel.
Molding tube socket 2 is set to the upper surface of the bottom plate 11;The molding tube socket is equipped with accommodating chamber;The formed pipe
2 top is provided with guide surface 21.
In the present embodiment, molding tube socket 2 is hollow tubular.
In the present embodiment, molding tube socket 2 has two rows, per 5 molding tube sockets 2 of behavior.
In the present embodiment, guide surface 21 is the conical surface.
Formed pipe 3 is correspondingly arranged with the molding tube socket 2, and the formed pipe 3 is detachably arranged in the accommodating chamber;
The formed pipe 3 is the transparent hollow tube of both ends open.
In the present embodiment, it is 1 to be molded the length of tube socket 3 with the length ratio of formed pipe 3:4.
In the present embodiment, accordingly, formed pipe 3 is two rows, per five formed pipes 3 of behavior.
Provided by the present invention for preparing the device of lacrimal bolt, it is suitable for preparing lacrimal by raw material of pHEMA
Bolt, convenient for pHEMA gel formings, and it can prepare multiple lacrimal bolts simultaneously, greatly improve work efficiency;Meanwhile by
Transparent formed pipe is used to be molded in it, convenient for introducing ultraviolet light cross-linking in preparation process.
Although the present invention is disclosed above with preferred embodiment, it is not limited to the range that the present invention is implemented.Any
The those of ordinary skill in field in the invention scope for not departing from the present invention, improves when can make a little, i.e., every according to this hair
Bright done equal improvement, should be the scope of the present invention and is covered.