CN108208417A - Pet anti-oxidant nutritional agents and preparation method thereof - Google Patents

Pet anti-oxidant nutritional agents and preparation method thereof Download PDF

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Publication number
CN108208417A
CN108208417A CN201711499220.3A CN201711499220A CN108208417A CN 108208417 A CN108208417 A CN 108208417A CN 201711499220 A CN201711499220 A CN 201711499220A CN 108208417 A CN108208417 A CN 108208417A
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pet
parts
nutritional agents
oxidant
oxidant nutritional
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谢志恒
李成应
张庆
元晓琪
徐奇清
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Foshan Nanhai Eastern Along Pharmaceutical Co Ltd
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Foshan Nanhai Eastern Along Pharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K50/00Feeding-stuffs specially adapted for particular animals
    • A23K50/40Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/105Aliphatic or alicyclic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • A23K20/147Polymeric derivatives, e.g. peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/174Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/24Compounds of alkaline earth metals, e.g. magnesium
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/20Inorganic substances, e.g. oligoelements
    • A23K20/30Oligoelements

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
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  • Food Science & Technology (AREA)
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  • Health & Medical Sciences (AREA)
  • Inorganic Chemistry (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Birds (AREA)
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  • Mycology (AREA)
  • Fodder In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention provides a kind of pet anti-oxidant nutritional agents and preparation method thereof, it is related to pet nutrition technical field, the pet is with anti-oxidant nutritional agents using moringa powder, Quercetin, astaxanthin, glutathione, tea polyphenols, multi-vitamins and composite trace element as major function raw material, the free radical in pet body can be removed, mitigate damage of the free radical to body, improve the oxidation resistance of body.Above-mentioned pet, by being combined with internal free radical, can directly make pet interior free yl be reduced into acidic materials with anti-oxidant nutritional agents, so as to accelerate the excretion of free radical, and to the damage of Green Tea Extract;Meanwhile the active oxygen removed body by improving the activity of body antioxidase and generated, and then improve the oxidation resistance of pet.In addition, this product is pulvis, it is good to be directly sprinkling upon on diet feeding, palatability, is easy to pets.

Description

Pet anti-oxidant nutritional agents and preparation method thereof
Technical field
The present invention relates to pet nutrition technical field, more particularly, to a kind of pet anti-oxidant nutritional agents and its preparation side Method.
Background technology
In the world of the mankind, pet dog is our friend, these pet dogs do not entertain any attempt, are loyal to theirs Friend;You have the friend of oneself, and still, in pet in the eyes, its world only has you.Pet accompanies our time to have on earth How longAlthough sorry, the time together is also with regard to 10 years or so.Therefore how to ensure the health of pet also becomes increasingly Obtain the attention of pet owner.
The free radical theory that Harman just proposed aging in 1956, it is believed that excessive free radical and its induced in vivo Oxidation reaction cell is made to be damaged for a long time, lead to human senility and death.With advancing age, body cannot maintain Free radical generates the dynamic equilibrium between removing so that has excessive free radical accumulation in body.Excessive free radical Cell membrane lipids oxidation can be caused, the product malonaldehyde of lipid peroxidation also results in intracellular nucleic Acid denaturation and dysfunction, when Body just develops to aging when these detriments accumulate.Harman in 1972 proposes mitochondria aging concept again.Either aging Electrosome theory or the free radical theory of aging can all be attributed to the mitochondrial DNA damage related with free radical and missing And the continuous accumulation of mitochondria self-energy consumption, and the accumulation of mitochondria free radical is caused to increase, lead to mitochondrial function Thus missing leads to the continuous aging course of body.
Free radical is the mesostate of a variety of biochemical reactions in body vital movement, internal free radical either Endogenic or exogenous, extraneous many chemical factors (such as ionising radiation, atmosphere pollution, smoking) can all make Exogenous free radical is generated in organism;On the other hand, still there are many non-enzyme reaction and enzymatic reaction are (as thin in swallowed in organism Born of the same parents' system, mitochondria and microsome electronics conducting system, lipid peroxidation process etc.) it can all generate endogenous free radical.Body In metabolic process (catalysis of such as enzyme, the autoxidation of electron transmission, cell component) or by high-energy radiation and photodegradation etc. Effect can all stimulate and generate some free radicals, in addition, the oxidative pollutant (such as O3, NO2) in air also can be in vivo Start radical reaction.
Damage of the free radical to cell membrane can lead to the change of cell metabolism, function and structure, so as to cause many diseases Become.Free radical may act on protein, and the structure of protein is made to change, leads to cell functional disorders.The chemical nature of enzyme The overwhelming majority is protein, therefore often can also influence the activity of enzyme.Free radical can react with base or pentose, generation Base free radical forms free radical in the deoxyribose moieties of DNA, and DNA chain fracture or base is finally made to destroy, lack, makes core The integrality and configuration of acid molecule are destroyed, and hereditary information is caused to change, and organism is made to mutate or generate lesion;Seriously The DNA of damage can not be repaired, so that causing cell death.Free radical can make the ribose of composition nucleic acid, deoxyribose form dehydrogenation Free radical, so as to which DNA backbone fracture or base be caused to destroy;Free radical can make the glycan molecule hydroxylating in cell membrane, destroy thin Polysaccharide structures on after birth influence the performance of cell function;Free radical can also destroy polysaccharide by oxidative degradation, influence tissue Function, as the polysaccharide in brain tissue will influence the normal function of brain by destroying.
Therefore, with reference to the present situation of China's pet dog food, according to the physiological property of pet dog, researching and developing one kind can be clear Except body free radical, and a kind of food nutrition agent of pet dog oxidation resistance can be improved, become very necessary and urgent.
In view of this, it is special to propose the present invention.
Invention content
The first object of the present invention is to provide a kind of pet anti-oxidant nutritional agents, the anti-oxidant nutritional agents of the pet Using moringa powder, Quercetin, astaxanthin, glutathione, tea polyphenols, multi-vitamins and composite trace element as major function original Material, can not only provide protein, minerals, trace element and vitamins and other nutritious components, while can also carry for pet The immunocompetence and oxidation resistance of high pet, and then improve the oxidation resistance of pet.
The second object of the present invention is to provide a kind of preparation method of pet with anti-oxidant nutritional agents, and this method has system Standby simple process, operating procedure flow are simple, and are easy to the advantages that prepared by large-scale production.
A kind of anti-oxidant nutritional agents of pet provided by the invention, the anti-oxidant nutritional agents is mainly by moringa powder, quercitrin Element, astaxanthin, glutathione, tea polyphenols, multi-vitamins and composite trace element composition.
Further, in parts by weight, the anti-oxidant nutritional agents is mainly made of following raw material:Moringa powder 2~8 Part, 1~8 part of Quercetin, 1~5 part of astaxanthin, 2~10 parts of glutathione, 3~12 parts of tea polyphenols, multi-vitamins 0.01~ 10 parts, 0.01~10 part of composite trace element.
Further, in parts by weight, the anti-oxidant nutritional agents is mainly made of following raw material:Moringa powder 3 ~6 parts, 2~5 parts of Quercetin, 1~4 part of astaxanthin, 2~8 parts of glutathione, 4~10 parts of tea polyphenols, multi-vitamins 0.01~ 10 parts, 0.01~10 part of composite trace element.
Further, the content of catechin is 75~85% in the tea polyphenols;
Preferably, the catechin is Epigallo-catechin gallate (EGCG).
Further, the composite trace element includes manganese methionine, zinc methionine, ferrous glycine, magnesium aminosuccinate, ferment The mixture of one or more of female selenium and calcium propionate.
Further, the pet still further comprises active yeast with the raw material of anti-oxidant nutritional agents and biology is living Property peptide.
Further, in parts by weight, the active yeast is 0.01~5 part, biologically active peptide 0.01 ~5 parts.
Further, the biologically active peptide includes carnosine, muscles, bovine casein, wheat gluten, the molten egg of wheat alcohol In vain, the mixture of one or more of zeins or soybean protein.
Further, the pet still further comprises flavoring agent and carrier with the raw material of anti-oxidant nutritional agents.
A kind of preparation method of the anti-oxidant nutritional agents of pet provided by the invention, the preparation method include following step Suddenly:Above-mentioned raw materials are mixed to get to the anti-oxidant nutritional agents of the pet.
Compared with prior art, beneficial effects of the present invention are:
Pet provided by the invention with anti-oxidant nutritional agents with moringa powder, Quercetin, astaxanthin, glutathione, tea polyphenols, Multi-vitamins and composite trace element are major function raw material, can remove the free radical in pet body, mitigate free radical pair The damage of body improves the oxidation resistance of body.Above-mentioned pet with anti-oxidant nutritional agents by being combined with internal free radical, Pet interior free yl can directly be made to be reduced into acidic materials, so as to accelerate the excretion of free radical, and to the damage of Green Tea Extract; Meanwhile the active oxygen removed body by improving the activity of body antioxidase and generated, and then improve the oxidation resistance of pet. In addition, this product is pulvis, it is good to be directly sprinkling upon on diet feeding, palatability, is easy to pets.
Specific embodiment
Technical scheme of the present invention is clearly and completely described below in conjunction with embodiment, it is clear that described reality It is part of the embodiment of the present invention to apply example, instead of all the embodiments.Based on the embodiments of the present invention, the common skill in this field Art personnel all other embodiments obtained without making creative work belong to the model that the present invention protects It encloses.
According to an aspect of the present invention, the anti-oxidant nutritional agents of a kind of pet, the anti-oxidant nutritional agents is mainly by peppery Wood powder, Quercetin, astaxanthin, glutathione, tea polyphenols, multi-vitamins and composite trace element composition.
It is the effect of raw materials used composition in the present invention:
Moringa powder include about 20 kinds of amino acid, 46 kinds of antioxidants, anti-inflammatory compound, rich in abundant trace elements K, Manganese, chromium and arginine, lysine, leucine, phenylalanine etc. provide vitamin A, vitamin B, B1, B2, B3, B6, dimension Raw element C (ascorbic acid), vitamin E and macroscopical minerals, trace element provide good protein and dietary fiber.The present invention By moringa powder be applied to pet with can be played in anti-oxidant nutritional agents good anti-inflammatory, prevention infection, it is anti-oxidant and remove The effect of interior free yl.
In the present invention, the moringa powder includes Moringa crushed material and/or Moringa extract, wherein, the Moringa crushed material Comminuted material including Moringa whole plants and/or leaf of Moringa and/or moringa seeds;The Moringa extract is planted including Moringa complete stool Object and/or moringa oleifera leaf extractive and/or Moringa seed extract.
Preferably, grain size≤180 μm of the moringa powder;
It is furthermore preferred that the grain size of the moringa powder is 75 μm -106 μm.
Quercetin also known as quercetin, Quercetin are a kind of flavonoids, have and remove various active oxygen radical Ability, internal oxygen radical can be inhibited to generate, and certain inhibiting effect is respectively provided with to different prooxidant drugs.Together When, Quercetin, which also has, to reduce blood pressure, enhances capillary resistance, reduce capillary fragility, reducing blood lipid, expand coronal move The effects that arteries and veins, increase coronary blood flow.
Astaxanthin also known as astaxanthin, Astaxanthin are the superlative degrees of a Carotenoids and carotenogenesis Other product, in rediance, chemical constitution is similar to beta carotene.Therefore in nature, astaxanthin has most strong anti-oxidant Performance.It is widely present in the feather of living nature, particularly shrimp, crab, fish, frond, yeast and birds that content is higher, is ocean life One of main carotenoid in object.The present invention uses anti-using natural astaxanthin as antioxidant applied to pet of the present invention Chemotrophy agent, free radical that can be effectively in scavenger-cell enhance the ability of cytothesis, organism balance and reduction are maintained to decline Cell and DNA health are protected in the accumulation of old cell from inside to outside, so as to protect skin health, promote hair growth, anti-aging, Alleviate sports fatigue, invigorate, strengthen immunity.
Glutathione is a kind of tripeptides containing γ-amido bond and sulfydryl, is made of glutamic acid, cysteine and glycine. Glutathione has two kinds of forms of reduced form (G-SH) and oxidized form (G-S-S-G), in physiological conditions with reduced glutathione Account for the overwhelming majority.Change between glutathione reductase catalysis amphitypy.GSH-PX activity of the present invention is used applied to pet of the present invention In anti-oxidant nutritional agents, the free radical in human body can be disposed, as a kind of internal important antioxidant, protects many eggs Sulfydryl in white matter and enzyme equimolecular can also protect hemoglobin not aoxidized by hydrogen peroxide oxidation, free radical etc. so as to make It continues normally to play the ability of transport oxygen.Glutathione can be with entering the toxic compounds of human body, heavy metal ion or carcinogenic Substance etc. is combined, and it is promoted to excrete, and plays neutralization detoxication.
Tea polyphenols also known as antioxygen spirit, Victoria Polyphenols, the anti-polyhydroxyl class compound breathed out spirit, be contained by tealeaves, referred to as TP, main chemical compositions are catechin (flavanol compound), flavones and flavonols, anthocyan, phenolic acid and depside, gather Close the complex of the compounds such as phenols.Wherein catechin compounds are the bulk composition of tea polyphenols, account for tea polyphenols total amount 65%-80%.Catechin compounds mainly include catechin (EC), nutgall catechin (EGC), catechin and gallate (ECG) and 4 kinds of substances of nutgall catechin gallic acid ester (EGCG).Pet of the present invention tea polyphenols in anti-oxidant nutritional agents Harmful free radicals can be removed, block lipid peroxidation process, improve the activity of enzyme in body;Heavy metal in adsorbent mitigates The toxic action that heavy metal generates body, meanwhile, tea polyphenols also have the effect for improving liver function.
Multi-vitamins include lipoic acid, vitamin C, vitamin E.Lipoic acid is a kind of coenzyme for being present in mitochondria, Belong to a kind of compound in B family vitamin, containing double sulphur five-membered ring structures, electron density is very high, has significant electrophilic Property and the ability with radical reaction.Vitamin C, also known as L-AA are enol form saccharinic acids for acid hexose derivative Lactone, in vivo, vitamin C are a kind of antioxidants, and protection body is from the threat of free radical.Vitamin E is a kind of Liposoluble vitamin, hydrolysate are tocopherol, are one of most important antioxidants.The anti-oxidant nutrition of pet of the present invention Multi-vitamins, which can be eliminated, in agent leads to accelerated ageing and pathogenic free radical.
Composite trace element includes Cu, Zn, Se, Mn.Cu, Zn, Mn are superoxide dismutase (SOD) biosynthesis institutes Required trace element.Superoxide dismutase (SOD) is free radical scavenger, can remove the free radical of internal excess, carry High body immunity slows down aging, antifatigue.Cu, Se, Mn are glutathione peroxidase (GSH-Px) biosynthesis institutes Required trace element.The peroxide and hydroxyl that glutathione peroxidase removing generates in cellular respiration metabolic process are certainly By base, so as to mitigate the peroxidation of cell membrane polyunsaturated fatty acid.Pet of the present invention is with compound in anti-oxidant nutritional agents Trace element provides superoxide dismutase and glutathione peroxidase synthesizes required raw material, ensures that two kinds of enzymatic synthesis are filled Foot.
Pet of the present invention can remove the free radical in pet body with anti-oxidant nutritional agents, mitigate damage of the free radical to body Evil improves the oxidation resistance of body.Above-mentioned pet, by being combined with internal free radical, can directly be made with anti-oxidant nutritional agents Pet interior free yl is reduced into acidic materials, so as to accelerate the excretion of free radical, and to the damage of Green Tea Extract;It is meanwhile logical It crosses and improves the active oxygen that the activity removing body of body antioxidase generates, and then improve the oxidation resistance of pet.In addition, this Product is pulvis, and it is good to be directly sprinkling upon on diet feeding, palatability, is easy to pets.
In the preferred embodiment of the present invention, in parts by weight, the anti-oxidant nutritional agents mainly by with Lower raw material is made:2~8 parts of moringa powder, 1~8 part of Quercetin, 1~5 part of astaxanthin, 2~10 parts of glutathione, tea polyphenols 3~12 Part, 0.01~10 part of multi-vitamins, 0.01~10 part of composite trace element.
In the present invention, the above-mentioned typical but non-limiting content of moringa powder is:2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts or 8 Part.In the present invention, the above-mentioned typical but non-limiting content of Quercetin is:1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts or 8 Part.In the present invention, the above-mentioned typical but non-limiting content of astaxanthin is:1 part, 2 parts, 3 parts, 4 parts or 5 parts.In the present invention, on Stating the typical but non-limiting content of glutathione is:2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts.This hair In bright, the above-mentioned typical but non-limiting content of tea polyphenols is:3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, 11 parts Or 12 parts.In the present invention, the above-mentioned typical but non-limiting content of multi-vitamins is:0.01 part, 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts.In the present invention, the above-mentioned typical but non-limiting content of composite trace element is: 0.01 part, 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts or 10 parts.
In above-mentioned preferred embodiment, in parts by weight, the anti-oxidant nutritional agents is mainly by following raw material system Into:It is 3~6 parts of moringa powder, 2~5 parts of Quercetin, 1~4 part of astaxanthin, 2~8 parts of glutathione, 4~10 parts of tea polyphenols, compound 0.01~10 part of vitamin, 0.01~10 part of composite trace element.
Preferably, in parts by weight, the anti-oxidant nutritional agents is mainly made of following raw material:Moringa powder 4~5 Part, is answered at 2~4 parts of Quercetin, 2~3 parts of astaxanthin, 3~6 parts of glutathione, 5~8 parts of tea polyphenols, 2~5 parts of multi-vitamins Close 2~5 parts of trace element.
In the present invention, by the further adjustment and optimization to each component raw material dosage ratio, so as to advanced optimize The using effect of the anti-oxidant nutritional agents of pet of the present invention.
In the preferred embodiment of the present invention, the content of catechin is 75~85% in the tea polyphenols;
Preferably, the catechin is Epigallo-catechin gallate (EGCG).Epigallo-catechin gallate (EGCG) (EGCG) it is a kind of composition for being extracted from Chinese green tea, it is the main activity of green tea and water-soluble components, is in catechin The highest component of content accounts for the 9%-13% of green tea gross weight, because with special stereochemical structure, EGCG has very strong Antioxidant activity, antioxidant activity is at least ascorbic more than 100 times, is 25 times of vitamin E, can protect cell and DNA is undermined, it is believed that related with cancer, heart disease and other major diseases, these effects of EGCG are attributed to for this damage Their removing (anti-oxidant) abilities to oxygen radical.Above-mentioned Epigallo-catechin gallate (EGCG) is applied to pet of the present invention With the antioxygenic property that nutritional agents of the present invention can be significantly improved in anti-oxidant nutritional agents.
In the preferred embodiment of the present invention, the composite trace element includes manganese methionine, zinc methionine, sweet The mixture of one or more of propylhomoserin iron, magnesium aminosuccinate, yeast selenium and calcium propionate.
As a preferred embodiment, for compared to inorganic microelement, pet is for composite trace element Absorption rate higher, this not only contributes to control cost, while also is able to reduce due to dirty caused by metallic element discharge Dye;Further, trace element by raw material of composite trace element for pet can not only be provided, be also capable of providing as ligand The organic nutrient substances such as amino acid.
In the preferred embodiment of the present invention, the pet is still further comprised with the raw material of anti-oxidant nutritional agents Active yeast and biologically active peptide.
In above-mentioned preferred embodiment, in parts by weight, the active yeast is 0.01~5 part, and biology is living Property peptide be 0.01~5 part.
Preferably, in nutrition enhancer as described above, each raw material components dosage is as follows:2~8 parts of moringa powder, Quercetin 1 ~8 parts, it is 1~5 part of astaxanthin, 2~10 parts of glutathione, 3~12 parts of tea polyphenols, 0.01~10 part of multi-vitamins, compound micro- 0.01~5 part of 0.01~10 part of secondary element, 0.01~5 part of active yeast and biologically active peptide.
In the preferred embodiment of the present invention, the biologically active peptide include carnosine, muscles, bovine casein, The mixture of one or more of wheat gluten, wheat gliadin, zeins or soybean protein.
In the preferred embodiment of the present invention, the pet is still further comprised with the raw material of anti-oxidant nutritional agents Flavouring agent and dilution carrier.
As a preferred embodiment, above-mentioned flavouring agent is chicken liver meal, dilution carrier is glucose.Due to flavouring agent Seasoning effect is primarily served, waits functional associations little with anti-oxidant, thus can be adjusted as needed, likewise, carrying The dosage of body is limited without specific.
According to an aspect of the present invention, the preparation method of the anti-oxidant nutritional agents of a kind of pet, the preparation method packet Include following steps:Above-mentioned raw materials are mixed to get to the anti-oxidant nutritional agents of the pet.
The preparation method of the anti-oxidant nutritional agents of pet of the present invention, this method have preparation process simplicity, operating procedure stream Journey is simple, and is easy to the advantages that prepared by large-scale production.
Preferably, above-mentioned preparation method further includes the pet that will be obtained and crosses No. 1-No. 5 sieves with anti-oxidant nutritional agents, then The step of packing is packaged.
Technical scheme of the present invention is described further below in conjunction with embodiment and comparative example.
Embodiment 1
A kind of anti-oxidant nutritional agents of pet, in parts by weight, the anti-oxidant nutritional agents is mainly by following raw material It is made:
2 parts of moringa powder, 1 part of Quercetin, 1 part of astaxanthin, 2 parts of glutathione, 3 parts of tea polyphenols, 1 part of beta carotene, dimension life Plain 1.5 parts of E, 0.5 part of vitamin B1,1 part of manganese methionine, 0.5 part of zinc methionine, 1 part of ferrous glycine, active yeast are 0.1 part, biologically active peptide is 0.5 part of bovine casein, 0.5 part of chicken liver meal, 1 part of glucose;
Above-mentioned pet is with the preparation method of anti-oxidant nutritional agents, and after above-mentioned raw materials are sufficiently mixed, obtained pet is used anti- Chemotrophy agent.
Embodiment 2
A kind of anti-oxidant nutritional agents of pet, in parts by weight, the anti-oxidant nutritional agents is mainly by following raw material It is made:
8 parts of moringa powder, 8 parts of Quercetin, 5 parts of astaxanthin, 10 parts of glutathione, 12 parts of tea polyphenols, 1 part of beta carotene, 1 part of vitamin A, 0.5 part of vitamine D3,0.5 part of ferrous glycine, 1 part of magnesium aminosuccinate, active yeast are 2 parts, wheat alcohol Molten 1 part of albumen, 1 part of zeins, 0.5 part of chicken liver meal, 1 part of glucose;
Above-mentioned pet is with the preparation method of anti-oxidant nutritional agents, and after above-mentioned raw materials are sufficiently mixed, obtained pet is used anti- Chemotrophy agent.
Embodiment 3
A kind of anti-oxidant nutritional agents of pet, in parts by weight, the anti-oxidant nutritional agents is mainly by following raw material It is made:
3 parts of moringa powder, 2 parts of Quercetin, 1 part of astaxanthin, 3 parts of glutathione, 4 parts of tea polyphenols, 1 part of beta carotene, dimension life Plain 1 part of A, 1.5 parts of vitamin B1,0.3 part of vitamin B12,1.5 parts of yeast selenium, 1 part of calcium propionate, are lived at 1 part of magnesium aminosuccinate Property saccharomycete for 0.01~5 part, 0.5 part of zeins, 0.5 part of chicken liver meal, 1 part of glucose;
Above-mentioned pet is with the preparation method of anti-oxidant nutritional agents, and after above-mentioned raw materials are sufficiently mixed, obtained pet is used anti- Chemotrophy agent.
Embodiment 4
A kind of anti-oxidant nutritional agents of pet, in parts by weight, the anti-oxidant nutritional agents is mainly by following raw material It is made:
6 parts of moringa powder, 5 parts of Quercetin, 4 parts of astaxanthin, 8 parts of glutathione, 10 parts of tea polyphenols, 1 part of vitamin E, dimension life Plain 0.5 part of B1,1 part of vitamin B12,1 part of manganese methionine, 1 part of zinc methionine, active yeast are 3 parts, 0.5 part of carnosine, ox 1 part of milk casein, 1 part of wheat gluten, 0.5 part of chicken liver meal, 1 part of glucose;
Above-mentioned pet is with the preparation method of anti-oxidant nutritional agents, and after above-mentioned raw materials are sufficiently mixed, obtained pet is used anti- Chemotrophy agent.
Embodiment 5
A kind of anti-oxidant nutritional agents of pet, in parts by weight, the anti-oxidant nutritional agents is mainly by following raw material It is made:
4 parts of moringa powder, 3 parts of Quercetin, 3 parts of astaxanthin, 5 parts of glutathione, 6 parts of tea polyphenols, 1 part of beta carotene, dimension life Plain 1 part of A, 1 part of vitamine D3,1 part of vitamin E, 1 part of vitamin B1,1 part of vitamin B12,1 part of manganese methionine, egg ammonia Sour 0.5 part of zinc, 1 part of ferrous glycine, 0.6 part of magnesium aminosuccinate, 1 part of yeast selenium, active yeast are 0.01~5 part, wheat paddy 1 part of albumen, 1 part of wheat gliadin, 0.5 part of chicken liver meal, 1 part of glucose;
Above-mentioned pet is with the preparation method of anti-oxidant nutritional agents, and after above-mentioned raw materials are sufficiently mixed, obtained pet is used anti- Chemotrophy agent.
Embodiment 6
The present embodiment is in addition to tea polyphenols are Epigallo-catechin gallate (EGCG) in raw material, remaining is the same as embodiment 5.
Comparative example 1
A kind of anti-oxidant nutritional agents of pet, this comparative example in raw material in addition to moringa powder is not included, remaining is the same as embodiment 5.
Comparative example 2
A kind of anti-oxidant nutritional agents of pet, this comparative example in raw material in addition to Quercetin is not included, remaining is the same as embodiment 5.
Comparative example 3
A kind of anti-oxidant nutritional agents of pet, this comparative example in addition to astaxanthin and glutathione is not included in raw material, remaining With embodiment 5.
Experimental example 1
To show that pet of the present invention can not only provide protein, minerals, micro member with anti-oxidant nutritional agents for pet Element and vitamins and other nutritious components, while the immunocompetence and oxidation resistance of pet can be also improved, and then improve pet Oxidation resistance, it is existing special to carry out following administering transgenic, and respectively to superoxide dismutase (SOD), malonaldehyde (MDA), one The liver function of nitrogen oxide (NO) and feeding pet is detected, wherein:
Superoxide dismutase is the scavenger of internal oxygen radical, can be disproportionated ultra-oxygen anion free radical and generate Hydrogen oxide and water provide protective barrier for body resistance oxidative damage.The height of SOD can reflect that body removes oxygen certainly indirectly By the ability of base.
Malonaldehyde is the polyunsaturated fatty acid in oxygen radical attack biomembrane, cause lipid peroxidation and the fat that is formed Matter Peroxidation Product, is one of most simple, the reliable index for reflecting oxidative damage, content number can reflect tissue Lipid peroxidation or intensity.
Nitric oxide is one of member of free radical activity nitrogen cluster generated in oxidative stress, and the raising of NO contents reflects Tissue oxidizing stress intensity increase.Under normal physiological status, the free radical in healthy animal body remains dynamic equilibrium, Although animal body in itself to balance have certain regulating power, encounter stress when, this balance will be broken, so as to draw Play the health status of animal.
Most basic in liver power checking, most important index is exactly transaminase, generally include serum glutamic pyruvic transminase (ALT) and Glutamic-oxalacetic transaminease (AST) two.Glutamic-pyruvic transaminase is primarily present in the soluble fraction of liver cell magma, and liver cell is inflamed disease During change, cellular swelling, necrosis or liver plasma membrane permeability is caused to increase, can glutamic-pyruvic transaminase be made to be released to blood circulation In, increase glutamic-pyruvic transaminase in blood.Glutamic-oxalacetic transaminease is primarily present in liver cell mitochondria, when liver generation is serious bad During dead or destruction, it can just cause the notable raising of glutamic-oxalacetic transaminease.Liver is removing toxic substances organ maximum in body, daily will be into Row food digestion and removing toxic substances.Many harmful substances will be converted to pair including heavy metal, drug, chemical substance etc. in liver The harmless substance of body, and a large amount of free radical can be generated in this process, therefore the inside and outside source free love Ji Shui of liver It puts down also compared with other organs height.Free radical can be removed by body under normal circumstances, but when antioxidant ability of organism is low, liver The ability for removing free radical is just decreased obviously.Number of free radical raising can lead to lipid peroxidation on liver plasma membrane in liver, break Bad cell structure leads to necrosis of liver cells, and serum transaminase can increase, and induces liver diseases.Therefore free radical and antioxidant Dysequilibrium is to cause the one of the major reasons of liver diseases.
Specific experimental method is as follows:
(1) test material
" match level number R-King " system that basic dog grain is provided by Lei meter Gao animal nutritious healths Science and Technology Ltd. of Foshan City Arrange into dog grain;
The anti-oxidant nutritional agents of the pet that the embodiment of the present invention 5, embodiment 6 and comparative example 1~3 are prepared.
(2) experimental animal
The old beasle dog provided by Lei meter Gao animal nutritious healths Science and Technology Ltd. of Foshan City pet breed true field 60, the situations such as health, weight are basically identical, the age between 8~10 years old, wherein bitch 30, public dog 30.In property respectively On the basis of other, using random fashion, it is divided into test group and control group, wherein every group of public affairs dog 5,5 female.
(3) trial
All experiment dogs concentrate raising by enclosed breeding management is used uniformly, and a dog one is given up, and quantitative feeding (presses weight 2% calculate scale of feeding), each feeding is primary sooner or later daily, wherein the basic dog grain of control group dog feeding, the basic dog of test group feeding Grain+test meal nutritional agents 5g;Ensure drinking-water, doghouse is swept in timing.Test period is 14 days, is tested in June, doghouse is put down Equal temperature is 31.6 DEG C (± 2 DEG C).
(4) collection of specimens and detection method
Blood is acquired in the early morning one day after of experiment the 1st day, the 7th day and the 14th day, and 5ml is adopted on an empty stomach using hind leg vein, The heart is left with centrifuge 3,500 15 minutes, detaches serum, and it is to be measured to be placed in preservation in -70 DEG C of low temperature refrigerators.
Wherein:Superoxide dismutase (SOD), malonaldehyde (MDA), nitric oxide (NO) be respectively adopted SOD kits, MDA kits, the detection of NO kits.Glutamic-pyruvic transaminase (ALT), glutamic-oxalacetic transaminease (AST) are given birth to using Full automatic animal in serum Change instrument detection, testing inspection result is for example following shown:
Table 1:Influence (U/ml) to SOD enzyme activities in serum
The SOD contents that can be seen that each test group from above-mentioned result of the test are on a declining curve, 5 He of the embodiment of the present invention The SOD contents of embodiment 6 are apparently higher than comparative example 1~3 and the content of control group, and the difference compared with the control group at 14 days Significantly, wherein the superoxide dismutase activity of embodiment 6 is most strong after 14 days.Pet of the present invention is shown with anti-oxidant nutrition The ability that beasle dog removes body free radical can be remarkably reinforced in agent.
Influence (nmol/ml) of the table 2 to MDA contents in serum
Influence (μm ol/ml) of the table 3 to serum NO Free Radical Level
By above-mentioned table 2 and table 3 it is found that after experiment carries out 14 days, the MDA's and NO of the embodiment of the present invention 5 and embodiment 6 Content is substantially reduced than comparative example 1~3 and control group, shows to dote on using what the embodiment of the present invention 5 and embodiment 6 were prepared The beasle dog that object is fed with anti-oxidant nutritional agents, body lipid peroxidation intensity and oxidative stress intensity all compare comparative example 1~3 and the beasle dog of control group decrease, i.e., pet of the present invention improves the antioxygen of beasle dog body with anti-oxidant nutritional agents Change ability.
Influence (U/l) of the table 4 to gpt level in serum
Influence (U/l) of the table 5 to glutamic-oxalacetic transaminease level in serum
Each test group beasle dog glutamic-pyruvic transaminase (ALT) during the experiment and paddy are can be seen that from above-mentioned result of the test Careless transaminase (AST) is all in normal physiologic range, but the Gu Bingzhuan of beasle dog that the embodiment of the present invention 5 and embodiment 6 are fed Ammonia enzyme and glutamic-oxalacetic transaminease are lower all than control group in the level of 7 days and 14 days, and are presented during testing and continuously decrease trend, The ability that liver removes free radical can be improved by demonstrating the agent of experiment food nutrition.
In conclusion pet of the present invention can remove the free radical in pet body with anti-oxidant nutritional agents, mitigate free radical Damage to body improves the oxidation resistance of body.Above-mentioned pet with anti-oxidant nutritional agents by with internal free base junction It closes, pet interior free yl can directly be made to be reduced into acidic materials, so as to accelerate the excretion of free radical, and to the damage of Green Tea Extract Evil;Meanwhile the active oxygen removed body by improving the activity of body antioxidase and generated, and then improve the anti-oxidant energy of pet Power.In addition, this product is pulvis, it is good to be directly sprinkling upon on diet feeding, palatability, is easy to pets.
Finally it should be noted that:The above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations;To the greatest extent Pipe is described in detail the present invention with reference to foregoing embodiments, it will be understood by those of ordinary skill in the art that:Its according to Can so modify to the technical solution recorded in foregoing embodiments either to which part or all technical features into Row equivalent replacement;And these modifications or replacement, various embodiments of the present invention technology that it does not separate the essence of the corresponding technical solution The range of scheme.

Claims (10)

1. a kind of anti-oxidant nutritional agents of pet, which is characterized in that the anti-oxidant nutritional agents mainly by moringa powder, Quercetin, Astaxanthin, glutathione, tea polyphenols, multi-vitamins and composite trace element composition.
2. the anti-oxidant nutritional agents of pet according to claim 1, which is characterized in that in parts by weight, described anti- Chemotrophy agent is mainly made of following raw material:2~8 parts of moringa powder, 1~8 part of Quercetin, 1~5 part of astaxanthin, glutathione 2 0.01~10 part of~10 parts, 3~12 parts of tea polyphenols, 0.01~10 part of multi-vitamins and composite trace element.
3. the anti-oxidant nutritional agents of pet according to claim 1, which is characterized in that in parts by weight, described anti- Chemotrophy agent is mainly made of following raw material:3~6 parts of moringa powder, 2~5 parts of Quercetin, 1~4 part of astaxanthin, glutathione 2 0.01~10 part of~8 parts, 4~10 parts of tea polyphenols, 0.01~10 part of multi-vitamins and composite trace element.
4. according to the anti-oxidant nutritional agents of claims 1 to 3 any one of them pet, which is characterized in that in the tea polyphenols The content of catechin is 75~85%;
Preferably, the catechin is Epigallo-catechin gallate (EGCG).
5. according to the anti-oxidant nutritional agents of claims 1 to 3 any one of them pet, which is characterized in that described compound micro Element includes one or more of manganese methionine, zinc methionine, ferrous glycine, magnesium aminosuccinate, yeast selenium and calcium propionate Mixture.
6. according to the anti-oxidant nutritional agents of claims 1 to 3 any one of them pet, which is characterized in that the pet is used anti- The raw material of chemotrophy agent still further comprises active yeast and biologically active peptide.
7. the anti-oxidant nutritional agents of pet according to claim 6, which is characterized in that in parts by weight, the work Property saccharomycete be 0.01~5 part, biologically active peptide be 0.01~5 part.
8. the anti-oxidant nutritional agents of pet described according to claim 6 or 7, which is characterized in that the biologically active peptide includes One in carnosine, muscles, bovine casein, wheat gluten, wheat gliadin, zeins or soybean protein Kind or several mixtures.
9. according to the anti-oxidant nutritional agents of claims 1 to 3 any one of them pet, which is characterized in that the pet is used anti- The raw material of chemotrophy agent still further comprises flavouring agent and dilution carrier.
10. a kind of preparation method according to the anti-oxidant nutritional agents of any one of claim 1~9 pet, feature exists In the preparation method includes the following steps:Any one of claim 1~9 raw material is mixed to get to the pet With anti-oxidant nutritional agents.
CN201711499220.3A 2017-12-29 2017-12-29 Pet anti-oxidant nutritional agents and preparation method thereof Pending CN108208417A (en)

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CN111903863A (en) * 2020-07-21 2020-11-10 北京和联四海生物科技有限公司 Compound feed additive for improving bone and joint health of pets and application thereof
CN112369525A (en) * 2020-11-12 2021-02-19 上海比瑞吉宠物用品股份有限公司 Dog food suitable for old dogs and preparation method thereof
CN113615767A (en) * 2020-05-06 2021-11-09 晨光生物科技集团股份有限公司 Feed containing quercetagetin and application thereof
CN116391671A (en) * 2023-03-28 2023-07-07 北京喜伴国际贸易有限公司 Method for reducing cholesterol content of eggs by using tea polyphenol

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108967812A (en) * 2018-07-25 2018-12-11 江苏奥迈生物科技有限公司 A kind of tea polyphenol composite antioxidant for feedstuff and preparation method thereof
CN113615767A (en) * 2020-05-06 2021-11-09 晨光生物科技集团股份有限公司 Feed containing quercetagetin and application thereof
CN111903863A (en) * 2020-07-21 2020-11-10 北京和联四海生物科技有限公司 Compound feed additive for improving bone and joint health of pets and application thereof
CN112369525A (en) * 2020-11-12 2021-02-19 上海比瑞吉宠物用品股份有限公司 Dog food suitable for old dogs and preparation method thereof
CN116391671A (en) * 2023-03-28 2023-07-07 北京喜伴国际贸易有限公司 Method for reducing cholesterol content of eggs by using tea polyphenol
CN116391671B (en) * 2023-03-28 2023-10-03 北京喜伴国际贸易有限公司 Method for reducing cholesterol content of eggs by using tea polyphenol

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