CN108158630A - A kind of Intravascular Thrombus catching device - Google Patents
A kind of Intravascular Thrombus catching device Download PDFInfo
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- CN108158630A CN108158630A CN201810159203.3A CN201810159203A CN108158630A CN 108158630 A CN108158630 A CN 108158630A CN 201810159203 A CN201810159203 A CN 201810159203A CN 108158630 A CN108158630 A CN 108158630A
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- bolt
- thrombus
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- catching device
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- 208000007536 Thrombosis Diseases 0.000 title claims abstract description 98
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- 238000002583 angiography Methods 0.000 description 9
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- 230000001154 acute effect Effects 0.000 description 6
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- 238000010586 diagram Methods 0.000 description 4
- 206010008132 Cerebral thrombosis Diseases 0.000 description 3
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- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0061—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof swellable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
- A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Public Health (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Surgical Instruments (AREA)
Abstract
A kind of Intravascular Thrombus catching device, system and transport system are tied including taking, and guiding sheath, take tie system include one can self-expanding take bolt stent, transport system includes a push-and-pull seal wire, it push-and-pull seal wire and takes and ties system and be connected, it is interior that guiding sheath can will take bolt system compresses to be folded and stowed in, it is characterised in that：Described takes the proximal part of bolt stent to interconnect the structure of the tubulose formed or caged by multiple unit grids, and described takes the distal portions of bolt stent to interconnect the structure of the net bag-shaped formed or sack shape by multiple unit grids.There is the present invention thrombus to arrest rate height, and thrombus is not easy to fall off during withdrawing, and the submissive type of transport system is good, take the advantages that small to blood vessel injury during bolt.
Description
Technical field
The present invention relates to a kind of a kind of medical instrument of interventional treatment of medical instruments field, more particularly to a kind of Intravascular Thrombus
Catching device.
Background technology
Acute cerebral thrombosis is mainly the most common lethal and crippling disease of central nervous system caused by cerebrovascular thrombosis
Disease.Cerebral thrombus has the characteristics that incidence is high, disability rate is high, the death rate is high and high recurrence rate.According to the statistics of Beijing one
Data shows, the incidence of Beijing's acute cerebral hemorrhage event in recent years is in the trend that is decreased obviously, and acute cerebral thrombosis event
Incidence but significantly rises, that is, acute cerebral hemorrhage occurs accounts for the ratio of cerebral apoplexy to be down to 16% by 42%, and acute cerebral thrombosis occurs
Ratio rise to 81.6% by 55.8%, it can be seen that cerebral thrombus has become the first big disease of brain.
Leading to again for blood vessel is the key that treatment acute ischemic cerebral apoplexy.The therapy for the treatment of Intracranial thrombus is main at present
There are two major class, only pass through drug thrombolysis mode and the mechanical mode that bolt and drug thrombolysis is taken to be combined.Drug thrombolysis can lead to
Cross intravenous injection rt-PA（Tissue-type plasminogen activator）Or urokinase can also be contacted with thrombus by intra-arterial
Thrombolysis, platelet aggregation-against and anticoagulant treatment etc..Although thromboembolism treatment has been shown to preferably improve nerveous system
The prognosis of system, but drug thrombolysis still faces the problem of some are anxious to be resolved, is that thrombolysis time window is short first, US National god
Through disease and palsy research institute（The National Institute Neurological Disorders and Stroke
Rt-PA Stroke Study Group, NINDS）Research think, intravenous thrombolysis should morbidity 3 hours within carry out, move
Arteries and veins thrombolysis time window should be within 6 hours, and so short thrombolysis time window causes the only patient of 4.5%-6.3% can
Receive thromboembolism treatment;Secondly, the revascularization time of drug thrombolysis is long, and the revascularization time may be the weight for influencing clinical prognosis
One of factor is wanted, regardless of being intravenous thrombolysis or Arterial thrombolysis, the revascularization time at least needs 1-2 hours;Again, it is molten
Bolt treats the thrombus for being suitable only for small volume, unsatisfactory to large volume thrombus treatment effect；And some patients are not suitable for
Thromboembolism treatment.
In order to solve the problems, such as said medicine thrombolysis, thrombus is eliminated into the heat of recent researches by the way of machinery
Point.Machinery takes bolt to include following methods：Aspirate thrombi, catching device take the broken bolt of bolt, laser.Aspirate thrombi is taking fritter embolus timeliness
Fruit is preferable, but when embolus is larger, and the embolus of distal end is easy to escape, and cumbersome and easily hurts blood vessel；It grabs at present
Catching device takes the method for bolt easy to operate, also smaller to the injury of blood vessel, but cannot often arrest thrombus, it is often necessary to repeatedly
It takes bolt or needs to be aspirated using guiding catheter simultaneously when arresting, the fine grained chippings otherwise to come off on thrombus can escape and hinder
Fill in distal vessels；The broken bolt of laser, this method operation difficulty is big, and laser energy is too low then invalid, excessively high and can damage blood vessel, and
And easily cause various complication.
Chinese invention patent CN103417258.B discloses a kind of intracranial vascular thrombus removal equipment, the device include take bolt device,
Guiding wire, push-and-pull seal wire and outer sheath, take bolt device to be connected with push-and-pull seal wire, mounted push-and-pull seal wire with bolt device is taken to be pressed hold
In outer sheath, in expanded position, bolt device is taken to be pushed out outer sheath, bolt device is taken to be provided with a certain number of convexes on its inner wall
The portion of rising.
Chinese invention patent application CN104000635.A discloses one kind and takes bolt device and take pin device, and it is netted to take bolt device
Structure simultaneously limits tube chamber, and can switch between retrieving position and expanded position, takes the reticular structure of bolt device equipped with multiple
The indent for stretching into the three-D profile of official jargon is done, and reticular structure is fixed at the both ends of interior female rod.
The thrombus catcher of above-mentioned netted tubular structure is although easy to operate, but it is hung in itself by stent grid
Firmly thrombus, and thrombus is between stent periphery and blood vessel, even if it increases internal projection or is connected with interior female rod, still
The thrombus that can be shredded during stent is unfolded can not be avoided, the fragment of formation has probability to take off during pulling plug instrument is withdrawn
It falls, takes bolt effect and unreliable, doctor in order to overcome this problem, generally requires to lead with the use of a sacculus at present
Pipe, using sacculus come blocking blood flow, to prevent the thrombus to come off fragment from can rush at distal vessels by blood flow；Netted tube chamber takes bolt
Device is because of its adherence quality with blood vessel, can be very big to the damage of the inner wall of blood vessel if the adjustment of stent radial load is improper and excessive.
In the invention " taking bolt device " of the patent No. ZL200620164685.4 of China's bulletin, have the function of by elastic memory
The umbrella of two one short three-jaws of length, net one circular configuration of formation having with periphery take pin device, are made by outer drawing push-pull rod
Three-jaw closes up and is recovered into thrombus pocket in outer tube in umbrella portion, and thrombus is taken out.
U.S. patent Nos US2009/0240238.A1 discloses one kind and takes pin device, and there are one be fixed on one to tool
Elongated shaft end can self-expanding snare and a folding bag made of flexible non-porous material attached to it
Device is placed in embolism position by son by elongated shaft along internal channel, opens sack by thrombus packet in the inner.
Although it is above-mentioned it is basket take the escape of anti-tampon fragment that bolt device can be centainly, obvious shortcoming is, body
Product is often excessive, can not be used in the cerebral arterys such as M1, M2 sections thinner of arteria cerebri media of blood vessel diameter.
Chinese invention patent application CN201110222609.X and Chinese invention patent CN201120281795.X are disclosed
A kind of thrombus suction catheter, including suction tube, the suction tube includes tube socket, the tube socket connecting conduit, the suction
Mobilizable on the outer wall of pipe to be arranged with casing, described sleeve pipe includes Y types connector, double lumen tube and sacculus, the Y types connector
Double lumen tube is connected, sacculus is set on the distal end outer wall of double lumen tube, can be included in the suction tube into interference wire, the interference
Outside the distal end of the extended suction tube in distal end of wire.This, which takes to tie to unite, can quickly remove the blood for being dispersed in blood vessel extensive region
Bolt and the embolism for handling coronary artery tip capilary, and when encounter volume it is big and it is high eat thick thrombus when, using interference metal
Silk is aspirated again after breaing up thrombus.
U.S. Patent application US2010/0049147A1 discloses another thrombus suction catheter.U.S. Patent application
US2007/0161963A1 also discloses that a kind of thrombectomy aspiration catheter system.
Above-mentioned suction takes that tie system effect when taking fritter embolus preferable, but is blocked in order to prevent when taking massive
Suction tube needs to aspirate again after smashing thrombus to pieces repeatedly, cumbersome and is easy to hurt blood vessel.
From above discussion it is found that in above patent document take pin device and it is existing take bolt technology, all have
One or more defect.Therefore, it is necessary to which the prior art is further improved, a kind of better taking thrombus of desired design
Device.
Invention content
In order to solve the technical issues of above-mentioned, the object of the present invention is to provide a kind of Intravascular Thrombus catching device, with following
Feature：First, keeping the thrombus catcher of its netted tubular structure easy to operate and to the injury of blood vessel also smaller spy
Point optimizes its structure, improves the thrombus capture rate of thrombus catcher.Thrombus catcher need to have the higher steady the thrombus arrested
It is qualitative, and the thrombus that while withdrawing goes to sticks and staves is not easily to fall off；Second, thrombus catcher radial support power size needs are moderate, make instrument
The damage to vascular wall is reduced as far as possible；Third, netted tubular structure thrombus catcher can be contacted with thrombus take bolt branch
Effective active length of frame should be grown as far as possible, and invalid transition portion should be as short as possible, smaller to ensure to take bolt stent to have
Total length is reduced with this and takes risk of the bolt stent to injury of blood vessel；Fourth, transport system compliance is good, encephalic can be transported to
Thinner distal vessels；Fifth, thrombus catcher has certain developability in itself, ensure that doctor is using DSA（Digital Subtraction blood
Pipe radiography）Under technology, it can clearly identify that judgement takes the state for tying system.
The present invention is achieved by the following technical solutions：
Intravascular Thrombus catching device, including take tie system and transport system and guiding sheath, take tie system include one can oneself
Expansion takes bolt stent, and transport system includes a push-and-pull seal wire, push-and-pull seal wire and takes and ties system and be connected, and guides sheath can be with
Bolt system compresses will be taken to be folded and stowed in interior, it is characterised in that：The proximal part for taking bolt stent is by multiple units
Grid interconnects the tubulose of composition or the structure of caged, and the distal portions for taking bolt stent are mutual by multiple unit grids
Be connected the net bag-shaped of composition or the structure of sack shape.
It will take in the blood vessels during tying system release, and take the tubulose of bolt mount proximal end or the structure division of caged that can release
It is placed on target thrombus position, takes the net bag-shaped of bolt rack far end or the structure division of sack shape that can discharge in the remote of target thrombus
End acts on by the structure division self-expanding for the tubulose or caged for taking bolt mount proximal end, makes to take on bolt stent unit grid in itself
Target thrombus entirety is tangled in incision thrombus, while the net bag-shaped of bolt rack far end or the structure division of sack shape is taken also oneself
Expansion is opened, and forms the catch net of a distal end, next by with thrombus take tie system withdraw it is external during,
Bolt mount proximal end part is taken when there is thrombus to be shredded and fled from by unit grid, broken bolt can be taken the string bag of bolt rack far end at this time
The structure division of shape or sack shape blocks and is accommodated in inside.This structure effectively solves the blood of conventional mesh tubular structure
Bolt catching device only relies on stent grid and tangles thrombus in itself, and going to sticks and staves the thrombus to come off can be along the disadvantage distally fled from circumferential outside stent
End.
" distal end " and " proximal end " should be understood as from the direction of the doctor in charge in the terms of the invention.
Therefore distal end is the side far from the doctor in charge, and proximal end is represented towards the side of the doctor in charge.If phrase " axial direction " is used in
In this document, it, which is understood as that, represents the direction that is pushed into of apparatus of the present invention, be device the longitudinal axis also with device along it forward
The longitudinal axis of mobile blood vessel overlaps.Bolt stent effective length is taken to refer to：Take bolt stent arrested during bolt is taken thrombus and
Prevent the part of effect that broken bolt is fled from.Inefficient length refers to：The transition for playing the role of connection in bolt stent is taken, and to grabbing
It catches thrombus and does not play direct part.
Above-mentioned technical proposal is further described：The knot of the net bag-shaped or sack shape that take bolt rack far end
Structure, the big opening region that proximal end is made of the interconnection of larger unit grid, is mutually connected by small cell grid
It connects and intersects to form in its distalmost end and be closed mouth regions.The big opening region of proximal end, which can be, allows thrombus to be easier to drop into net
It in the structure of pocketed or sack shape, and the use small cell grid of distal end and intersects closing in distalmost end, net can be formed
Pocketed blocks the thrombus fallen into inside stent.
Above-mentioned technical proposal is further described：The structure of the net bag-shaped or sack shape that take bolt rack far end
Closure mouth regions, the shape of hemisphere can be fixed to.Hemispherical distal end can provide preferably support to distal structure
Power, and the structure of dome-type is not easy by tortuous Blood vessel pattern, this structure is adherent with better vascular compliance and blood vessel
Property.
Above-mentioned technical proposal is further described：The structure of the proximal tubular or caged that take bolt stent,
Proximal end unit grid, which is interconnected and intersected in most proximal end, forms transition mouth reducing region.Stent most proximal end intersects to form and close up
Region, this region is takes bolt stent and push-and-pull seal wire tie point position to taking invalid transition part between bolt stent tubulose effective length
Point, this structure can allow the inefficient length to play a transition role short as far as possible.
Above-mentioned technical proposal is further described：The bolt stent that takes is that have super-elasticity by laser engraving
The marmem pipe material of effect, and metallic support made of sizing treatment after warp.It is golden made of marmem
Belonging to stent has enough radial supporting forces, can guarantee it with good adherence quality, marmem has hyperelastic
After can making the restraining force that bolt stent is taken to receive exterior circumferential very big deformation can occur for characteristic, and be taken after removing restraining force
Bolt stent remains to be completely recovered to its shape.This performance can compress the outer diameter for taking bolt stent, can match defeated into having
In the microtubular for sending instrument effect.
Above-mentioned technical proposal is further described：Described taking ties system impermeable X ray developing ring including there are one,
It is taking bolt stent with pushing and pulling at seal wire link position.Clinician can pass through blood vessel image equipment, such as DSA（Digital Subtraction
Angiography）It monitors impermeable X ray developing ring, and then understands the most proximal position for taking bolt stent in the blood vessels.
Above-mentioned technical proposal is further described：Described taking ties system including there are one roentgenopaque springs
The protection head end of cast formula, at the distal-most position for taking bolt stent.Clinician can be by blood vessel image equipment, such as
DSA（Digital subtraction angiography）It monitors impermeable X ray protection head end, and then understands the distalmost end position for taking bolt stent in the blood vessels
It puts, while protects head end using soft spring ring form, when can avoid the instrument from going out microtubular, bolt branch is taken caused by maloperation
Frame distalmost end is directly withstood on vascular wall and the damage caused by blood vessel.
Above-mentioned technical proposal is further described：Described take ties system and includes roentgenopaque filament, twines
It is wound on the bar for the unit grid for taking bolt stent.Clinician can pass through blood vessel image equipment, such as DSA（Digital Subtraction
Angiography）When monitoring roentgenopaque filament, but the position of filament is seen by production, understand the complete opening for taking bolt stent
With by the compressive state of thrombus, and then judge that thrombus taken bolt stent arrests situation.
Above-mentioned technical proposal is further described：Lubricant coating is coated on the push-and-pull seal wire, lubricant coating is
PTFE coatings or hydrophilic coating.Lubricant coating reduces resistance of the instrument during push-and-pull, increases the handling of instrument.
Above-mentioned technical proposal is further described：The guiding sheath is polymer material polytetrafluoroethylene (PTFE).Draw
Lead sheath pipe, which can shrink to take, to be tied in system to guiding sheath, and microtubular internal diameter can be equal to by guiding the internal diameter of sheath, and facilitating will be entire
Device is sent into microtubular；The material of polytetrafluoroethylene (PTFE) has smaller friction coefficient, reduces instrument and is pushing into microtubular
In resistance.
Above-mentioned technical proposal is further described：The push-and-pull seal wire uses the design of gradual change diameter, and distal end is straight
Diameter is small, and proximal diameter is big.The minor diameter of wire distal is pushed and pulled, ensure that push-and-pull wire distal is sufficiently flexible, possess smaller song
Rate radius makes it preferably adapt to the tortuous blood vessel of brain distal end, and the thicker diameter of proximal end, and push-and-pull seal wire is made to have distal end
There is certain hardness, to provide reliably support strength when push takes and ties system in microtubular.
Above-mentioned technical proposal is further described：The transport system includes support spring circle, support spring circle
It is wrapped on the partial-length of the push-and-pull seal wire of the thin diameter in distal end.Support spring encloses the push-and-pull seal wire for strengthening the thin diameter in distal end
Support strength, to improve proximal end push power by push-and-pull seal wire to distally taking the efficiency for tying system and transmitting, while support spring circle
The alloy of platiniferous may be used, roentgenopaque characteristic can allow push-and-pull seal wire also to have development capability.
The present invention has the following advantages compared with prior art：
First, keeping the thrombus catcher of its netted tubular structure easy to operate and to the injury of blood vessel also smaller feature
Outside, the thrombus gone to sticks and staves when thrombus catcher being made to have arrested more high stability to thrombus, and being withdrawn is not easily to fall off.
Second, thrombus catcher radial support power is of moderate size, instrument is made to reduce the damage to vascular wall as far as possible.
Third, taking, effective active length of bolt stent is long, and the inefficient length of transitional function is short, guarantee take bolt stent have compared with
Small total length is reduced with this and takes risk of the bolt stent to injury of blood vessel.
Fourth, the compliance of the push seal wire of the present invention is good, the thinner distal vessels of such as encephalic can be transported to.
Fifth, thrombus catcher has certain developability in itself, ensure that doctor is using DSA（Digital subtraction angiography）
Under technology, it can clearly identify that judgement takes the state for tying system.
Description of the drawings
The example of the present invention will be explained by the following drawings：
Fig. 1 is a kind of structure diagram of the example of Intravascular Thrombus catching device of the present invention.
Fig. 2 is that the three-dimensional structure space schematic diagram for tying system is taken in example shown in FIG. 1.
Fig. 3 is that the example of Intravascular Thrombus catching device of the invention another takes the structure diagram for tying system, is being taken
Roentgenopaque filament is wound on the bar of the unit grid of bolt stent.
Fig. 4 is that taking for example shown in Fig. 3 ties system, and DSA is used in doctor（Digital subtraction angiography）Under technology, institute
The schematic diagram of instrument development seen.
Fig. 5 is the process schematic that example shown in Fig. 1 takes out intravascular target thrombus（One）.
Fig. 6 is the process schematic that example shown in Fig. 1 takes out intravascular target thrombus（Two）.
Fig. 7 is the process schematic that example shown in Fig. 1 takes out intravascular target thrombus（Three）.
Fig. 8 is the process schematic that example shown in Fig. 1 takes out intravascular target thrombus（Four）.
Fig. 9 is the process schematic that example shown in Fig. 1 takes out intravascular target thrombus（Five）.
Specific embodiment
Principle according to the present invention, with reference to the figures above, the example of several thrombus catchers is announced herein.But it announces herein
Example be only the present invention in some examples.The details announced in detail only as the basis of application claim and has taught phase
How the personnel for closing technical background are suitably using the present invention.
A kind of example of Intravascular Thrombus catching device of Fig. 1 displaying present invention, including take tie system and transport system and
Guide sheath (300), take tie system include one can self-expanding take bolt stent (100), transport system leads including a push-and-pull
Silk (200), push-and-pull seal wire (200) tie system and are connected with taking, and the proximal part for taking bolt stent (100) is by multiple lists
First grid interconnects the tubulose of composition or the structure of caged, and the distal portions for taking bolt stent (100) are by multiple lists
First grid interconnects the net bag-shaped of composition or the structure of sack shape.The bolt stent (100) that takes is that have by laser engraving
There is the marmem pipe material of super-elasticity effect, and metallic support, alloy material can made of sizing treatment after passing through
Using the Nitinol with super elastic properties.Described taking ties system impermeable X ray developing ring (110) including there are one,
Taking bolt stent (100), platinumiridio can be used in the material of developing ring (110), described with pushing and pulling at seal wire (200) link position
Take tie system include there are one roentgenopaque spring ring form protection head end (120), taking bolt stent (100)
At distal-most position, platinum-tungsten alloys can be used in the material of protection head end (120).Push and pull seal wire (200) setting using gradual change diameter
Meter, distal diameter is small, and proximal diameter is big, and hyperelastic dilval can be used in length 180cm, material, ensures that it is good
Compliance, be coated with lubricant coating in push-and-pull seal wire (200), lubricant coating is PTFE coatings.Lubricant coating reduces instrument and exists
Resistance during push-and-pull increases the handling of instrument.Guiding sheath (300) can will take bolt system compresses to fold and receive
In being contained in, guiding sheath (300) is polymer material polytetrafluoroethylene (PTFE), and the internal diameter of guiding sheath (300) is equal to microtubular (400)
Internal diameter, length are preferably 65mm.As shown in Fig. 2, take the net bag-shaped of bolt stent (100) distal end or the structure of sack shape, proximal end
By the big opening region (101) that forms of larger unit grid interconnection, be distally interconnected by small cell grid and
It intersects to form in its distalmost end and is closed mouth regions (102), take the net bag-shaped of bolt stent (100) distal end or the structure of sack shape
Closure mouth regions (102), the shape of hemisphere can be fixed to, ensured from taking the thrombus that bolt stent (100) proximal end comes off can be with
Big opening region (101) is fallen into, and by being closed mouth regions (102) storage and stopping.Take bolt stent (100) proximal tubular or
The structure of caged, proximal end unit grid, which is interconnected and intersected in most proximal end, forms transition mouth reducing region (103).
The example of another Intravascular Thrombus catching device of Fig. 3 displaying present invention, exists compared to the difference of example shown in Fig. 1
In：The taking of this example ties system and includes roentgenopaque filament (130), is wrapped in the unit for taking bolt stent (100)
On the bar of grid.According to track as shown in Figure 3, spiral is wrapped on the bar of unit grid.When clinician uses blood vessel shadow
As learning equipment, such as DSA（Digital subtraction angiography）, doctor its will observe that completely open take ties on device screen
The developed image of system, image is as shown in figure 4, clinician sees the position of roentgenopaque filament (130), understanding by production
It takes the opening of bolt stent (100) and by the compressive state of thrombus, and then judges that target thrombus (500) is taken bolt stent (100)
Arrest situation.
The explanation of example shown in Fig. 1 is used for clinician below：Clinician uses DSA（Digital subtraction angiography）
Angiography is carried out to patient, determines the position of the interior target thrombus (500) of blood vessel (600).It is intervened using conventional vascular puncture
Microtubular (400) is distally transported to more than target thrombus (500) certain distance, i.e., position as shown in Figure 5 by technology, backward
The appropriate contrast agent of push-in in microtubular (400), carries out the angiography of thrombus distal end, judges target thrombus (500) approximate size,
Select the thrombus catcher of appropriate size.Then using the guiding role for guiding sheath (300), example shown in Fig. 1 is sent into micro-
Push in conduit (400) and gradually entire instrument.Microtubular is reached when taking the roentgenopaque protection head end (120) for tying system
(400) during distalmost end, i.e., position as shown in Figure 6 when, keep example shown in Fig. 1 whole motionless relative to human body and proximally withdraw
Microtubular (400) with withdrawing for microtubular (400), takes bolt stent (100) that will be unfolded in target thrombus (500) position, takes bolt
The unit grid of the tubulose of stent (100) proximal end or the structure division of caged is cut in itself tangles blood in target thrombus (500)
Bolt is whole, at the same take bolt stent (100) distal end net bag-shaped or sack shape structure division also can self-expanding open, form one
The catch net of distal end, microtubular (400) distalmost end withdraw the position for taking the developing ring for tying system (110) always, as shown in Figure 7
Position.It waits for and being more than 3 minutes later, make bolt stent (100) is taken to be fully expanded, when doctor judges to grab target thrombus (500)
After catching well, the entirety of example shown in Fig. 1 and microtubular (400) are rapidly withdrawn, the thrombus fallen at this time if any chopping will be taken
The net bag-shaped of bolt stent (100) distal end or the structure division of sack shape are arrested, as shown in Figure 8.When having arrested target thrombus
(500) when taking the bolt stent (100) to withdraw guiding catheter (700) inlet, the internal diameter of the guiding catheter (700) is than micro-
Conduit (400) internal diameter bigger, but its internal diameter is smaller than blood vessel (600) internal diameter, will certainly cause to take the part of bolt stent (100) outside
Thrombus can be retained in guiding catheter (700) outside, doctor can select to guiding catheter (700) extract negative pressure, make to rest on pipe
The thrombus of mouth enters in guiding catheter (700), this example can also be utilized to take the net bag-shaped or sack shape of bolt stent (100) distal end
Structure division the thrombus at nozzle is taken back because from take bolt stent (100) proximal end be detached from thrombus, bolt stent can be taken
(100) string bag of distal end is caught.Final take ties system and can withdraw from the example instrument for being wrapped in target thrombus (500) in vitro, complete
Into entirely taking bolt process.
Claims (10)
1. a kind of Intravascular Thrombus catching device, system and transport system and guiding sheath are tied including taking, is taken and is tied system and include one
It is a can self-expanding take bolt stent, transport system includes push-and-pull seal wire, and push-and-pull seal wire ties system and be connected with taking, guide sheath
It is interior that pipe can will take bolt system compresses to be folded and stowed in, it is characterised in that：The proximal part for taking bolt stent is by more
A unit grid interconnects the tubulose of composition or the structure of caged, and the distal portions for taking bolt stent are by multiple units
Grid interconnects the net bag-shaped of composition or the structure of sack shape.
2. a kind of Intravascular Thrombus catching device according to claim 1, it is characterised in that：The described bolt rack far end that takes
The structure of net bag-shaped or sack shape, proximal end by the big opening region that forms of larger unit grid interconnection, be distally by
Small cell grid, which interconnects and intersects to form in its distalmost end, is closed mouth regions.
3. a kind of Intravascular Thrombus catching device according to claim 2, it is characterised in that：The described bolt rack far end that takes
The closure mouth regions of the structure of net bag-shaped or sack shape can be fixed to the shape of hemisphere.
4. a kind of Intravascular Thrombus catching device according to claim 1, it is characterised in that：The proximal end for taking bolt stent
The structure of tubulose or caged, proximal end unit grid, which is interconnected and intersected in most proximal end, forms transition mouth reducing region.
5. a kind of Intravascular Thrombus catching device according to claim 1, it is characterised in that：The bolt stent that takes is to pass through
Laser engraving has the marmem pipe material of super-elasticity effect, and metallic support made of sizing treatment after warp.
6. a kind of Intravascular Thrombus catching device according to claim 1, it is characterised in that：Described take ties system and includes
One impermeable X ray developing ring is taking bolt stent with pushing and pulling at seal wire link position.
7. a kind of Intravascular Thrombus catching device according to claim 1, it is characterised in that：Described take ties system and includes
The protection head end of one roentgenopaque spring ring form, at the distal-most position for taking bolt stent.
8. a kind of Intravascular Thrombus catching device according to claim 1, it is characterised in that：Described take ties system and includes
Roentgenopaque filament is wrapped on the bar for the unit grid for taking bolt stent.
9. a kind of Intravascular Thrombus catching device according to claim 1, it is characterised in that：It is coated on the push-and-pull seal wire
Lubricant coating, lubricant coating are PTFE coatings or hydrophilic coating.
10. a kind of Intravascular Thrombus catching device according to claim 1, it is characterised in that：The guiding sheath is poly-
Close object material polytetrafluoroethylene (PTFE).
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810159203.3A CN108158630A (en) | 2018-02-26 | 2018-02-26 | A kind of Intravascular Thrombus catching device |
| CN202010912055.5A CN111904675B (en) | 2018-02-26 | 2018-02-26 | Thrombus taking support and thrombus capturing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810159203.3A CN108158630A (en) | 2018-02-26 | 2018-02-26 | A kind of Intravascular Thrombus catching device |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010912055.5A Division CN111904675B (en) | 2018-02-26 | 2018-02-26 | Thrombus taking support and thrombus capturing device |
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| CN108158630A true CN108158630A (en) | 2018-06-15 |
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| CN202010912055.5A Active CN111904675B (en) | 2018-02-26 | 2018-02-26 | Thrombus taking support and thrombus capturing device |
| CN201810159203.3A Pending CN108158630A (en) | 2018-02-26 | 2018-02-26 | A kind of Intravascular Thrombus catching device |
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| CN202010912055.5A Active CN111904675B (en) | 2018-02-26 | 2018-02-26 | Thrombus taking support and thrombus capturing device |
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| CN112155658B (en) * | 2020-10-29 | 2022-03-18 | 上海加奇生物科技苏州有限公司 | Thrombus taking bracket and thrombus catcher |
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| CN113413192A (en) * | 2021-07-26 | 2021-09-21 | 东南大学泰州生物医药与医疗器械研究院 | Diameter and length adjustable bolt taking device |
| CN113413192B (en) * | 2021-07-26 | 2022-09-23 | 东南大学泰州生物医药与医疗器械研究院 | Bolt taking device with adjustable diameter and length |
| CN113576599A (en) * | 2021-07-30 | 2021-11-02 | 北京泰杰伟业科技有限公司 | Thrombus retrieval device and self-expanding structure |
| CN114098904A (en) * | 2021-11-10 | 2022-03-01 | 北京泰杰伟业科技有限公司 | Thrombus collection device |
| CN114652394A (en) * | 2022-04-06 | 2022-06-24 | 苏州恒瑞宏远医疗科技有限公司 | Intravascular thrombus taking-out device |
| WO2024060892A1 (en) * | 2022-09-22 | 2024-03-28 | 神途医疗科技(上海)有限公司 | Embolism protection apparatus and medical device |
| CN115836927A (en) * | 2022-12-06 | 2023-03-24 | 杭州亿科医疗科技有限公司 | Bolt taking system |
| CN115836927B (en) * | 2022-12-06 | 2023-05-09 | 杭州亿科医疗科技有限公司 | Bolt taking system |
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| CN111904675B (en) | 2023-04-25 |
| CN111904675A (en) | 2020-11-10 |
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