CN108158610A - A kind of elastograph imaging method, device, equipment and ultrasound imaging probe - Google Patents
A kind of elastograph imaging method, device, equipment and ultrasound imaging probe Download PDFInfo
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Abstract
The invention discloses a kind of elastograph imaging method, device, equipment and ultrasound imaging probe, wherein the method includes：Control is arranged on the ultrasonic transducer of the ultrasound imaging probe body head towards tissue emissions ultrasonic wave to be detected and receives the first ultrasound echo signal of the Tissue reflectance to be detected；It generates the first predetermined electrical signals and encourages the Langevin-type transducer longitudinal vibration, when Langevin-type transducer longitudinal vibration, which drives the head of ultrasound imaging probe main body to act on the tissue to be detected, makes its generate deformation；Control is arranged on the ultrasonic transducer of the ultrasound imaging probe body head towards the tissue emissions ultrasonic wave to be detected and receives the second ultrasound echo signal of the Tissue reflectance to be detected；Elastogram information is determined according to first ultrasound echo signal and second ultrasound echo signal.The present invention enables to ultrasound imaging probe to be unaffected by the magnetic field, and can reduce the volume of ultrasound imaging probe, mitigate the weight of ultrasound imaging probe.
Description
Technical field
The present invention relates to ultrasonic imaging technique fields, and in particular to a kind of elastograph imaging method, device, equipment and ultrasound into
As probe.
Background technology
Since the variation of the coefficient of elasticity of same biological tissue is often related with pathological characters, such as normal structure suffers from breast
After the illnesss such as gland cancer, liver cancer, the coefficient of elasticity of part can significantly increase.Therefore the quantitative display of biological tissue's mechanical parameter
Available for positioning lesion and differentiate lesion nature, there is important medical value.Existing Ultrasonic Elasticity Imaging is typically head
First to tissue emissions ultrasonic wave to be detected and the first ultrasound echo signal of reception, tissue to be detected is then made to generate miniature deformation,
Again to the tissue emissions ultrasonic wave to be detected and the second ultrasound echo signal of reception, finally to the first ultrasound echo signal and second
Ultrasound echo signal is handled to obtain the response parameters such as displacement, strain, strain rate and the speed of tissue to be detected, and then estimate
Go out the relative value of the properties of material mechanics such as Young's modulus, modulus of shearing, Poisson's ratio and Lame constants.
Biological tissue to be detected is made to generate the mode of miniature deformation in existing way, typically operator's hand-held ultrasound is imaged
Probe applies pressure to tissue to be detected, and tissue to be detected is caused to deform upon；Or the ultrasonic imaging by carrying motor
Probe presses tissue to be detected automatically.
However, applying stressed mode by hand above by operator so that operating process is relatively complicated；And it above-mentioned carries
The ultrasound imaging probe of motor should be also configured with electronic other than being configured with ultrasound emission module and ultrasonic reception module
Machine, so that the volume of ultrasound imaging probe is larger, easily affected by magnetic fields.
Invention content
In view of this, an embodiment of the present invention provides a kind of elastograph imaging method, device, equipment and ultrasound imaging probe,
To solve the problems, such as that the existing ultrasound imaging probe volume using motor is larger, easily affected by magnetic fields.
First aspect present invention provides a kind of elastograph imaging method, including：Control is arranged on ultrasound imaging probe main body
The ultrasonic transducer on head towards tissue emissions ultrasonic wave to be detected and receive the Tissue reflectance to be detected first ultrasound return
Wave signal；It generates the first predetermined electrical signals and encourages the Langevin-type transducer longitudinal vibration, when Langevin-type transducer longitudinal vibration drives ultrasound
The head of imaging probe main body, which acts on the tissue to be detected, makes it generate deformation；Control is arranged on the ultrasound imaging probe
The ultrasonic transducer of body head is towards the tissue emissions ultrasonic wave to be detected and receives the of the Tissue reflectance to be detected
Two ultrasound echo signals；Determine that elastogram is believed according to first ultrasound echo signal and second ultrasound echo signal
Breath.
Optionally, it is described that elastogram is determined according to first ultrasound echo signal and second ultrasound echo signal
The step of information, including：The biography of shearing wave is determined according to first ultrasound echo signal and second ultrasound echo signal
Speed is broadcast, the shearing wave generates the waveform propagated after deformation from deformation position to vertical-depth for tissue to be detected；According to described
The spread speed of shearing wave determines the Young's modulus of tissue to be detected.
Optionally, described control is arranged on the ultrasonic transducer of the ultrasound imaging probe body head towards described to be checked
After the step of surveying tissue emissions ultrasonic wave and receiving the second ultrasound echo signal of the Tissue reflectance to be detected, further include：
Control is arranged on the ultrasonic transducer of the ultrasound imaging probe body head towards the tissue emissions ultrasonic wave to be detected simultaneously
Receive the third ultrasound echo signal of the Tissue reflectance to be detected；It is described according to first ultrasound echo signal and described
Two ultrasound echo signals determine that the step of spread speed of shearing wave includes：According to first ultrasound echo signal and described
Two ultrasound echo signals determine that the primary peak of the shearing wave corresponds to the sequence of sampled point in second ultrasound echo signal
Number n1；Determine that the secondary peak of the shearing wave exists according to first ultrasound echo signal and the third ultrasound echo signal
The serial number n of sampled point is corresponded in the third ultrasound echo signal2；Obtain the spread speed v of ultrasonic wave0, ultrasonic echo sampling
Frequency f；
The primary peak is calculated to the displacement s of the secondary peak：It obtains and receives described the
Two ultrasonic echos and the time interval t for receiving the third ultrasonic echo1；Calculate the spread speed of the shearing wave：
Optionally, the wave crest of the shearing wave is determined according to first ultrasound echo signal and X ultrasound echo signal
The step of serial number of sampled point being corresponded in the X ultrasound echo signal, including：Repeatedly choose the first ultrasonic echo letter
Number and signal of the X ultrasound echo signal in identical and/or adjacent predetermined amount of time, calculate the first surpassing of being selected
The cross correlation value of sound echo-signal and X ultrasound echo signal；When cross correlation value is less than predetermined value, the cross-correlation is determined
The serial number for being worth sampled point in corresponding predetermined amount of time corresponds to the sequence of sampled point as wave crest in the X ultrasound echo signal
Number；The X ultrasound echo signal includes the second ultrasound echo signal or third ultrasound echo signal.
Second aspect of the present invention provides a kind of elastogram device, including：First control unit is arranged on for controlling
The ultrasonic transducer of ultrasound imaging probe body head is towards tissue emissions ultrasonic wave to be detected and receives the tissue to be detected
First ultrasound echo signal of reflection；First exciting unit encourages the Langevin-type transducer for generating the first predetermined electrical signals
Longitudinal vibration, the head of ultrasound imaging probe main body is driven during the Langevin-type transducer longitudinal vibration, which to act on the tissue to be detected, makes its production
Raw deformation；Second control unit is arranged on the ultrasonic transducer of the ultrasound imaging probe body head towards institute for controlling
It states tissue emissions ultrasonic wave to be detected and receives the second ultrasound echo signal of the Tissue reflectance to be detected；Determination unit is used
In determining elastogram information according to first ultrasound echo signal and second ultrasound echo signal.
Third aspect present invention provides a kind of ultrasound imaging probe, including：Main body；At least one ultrasonic transducer, if
It puts on the head of the main body, for emitting ultrasonic wave and receiving ultrasound echo signal；Langevin-type transducer is arranged on the main body
On；The Langevin-type transducer under the excitation of the first predetermined electrical signals can longitudinal vibration and driving vibrate before and after the head of the main body.
Optionally, the main body includes forepart, and the front end of the Langevin-type transducer is fixedly connected with the rear end of the forepart；
Alternatively, the main body includes：Forepart, the front end of the Langevin-type transducer are fixedly connected with the rear end of the forepart；Rear portion, it is described
The rear end of Langevin-type transducer is fixedly connected with the front end at the rear portion.
Optionally, under second predetermined electrical signals excitation, the Langevin-type transducer is encouraged in the second predetermined electrical signals
Bending vibration and the head of the main body can be driven to swing laterally down.
Fourth aspect present invention provides a kind of elastogram equipment, including：Ultrasound imaging probe, display, memory
And processor, connection is communicated between the ultrasound imaging probe, the display, the memory and the processor,
Computer instruction is stored in the memory, the processor is by performing the computer instruction, so as to perform first party
Elastograph imaging method described in face or its any one optional embodiment.
Fifth aspect present invention provides a kind of computer readable storage medium, the computer-readable recording medium storage
There is computer instruction, the computer instruction is used to that the computer to be made to perform first aspect or its any one optional implementation
Elastograph imaging method described in mode.
Elastograph imaging method, device, equipment and the ultrasound imaging probe that the embodiment of the present invention is provided, are shaken using Lan Jiewen
The longitudinal vibration pattern of son is vibrated before and after driving the head of main body, and tissue to be detected can easily be made to generate deformation and obtain ultrasound time
Wave information is that may be such that tissue to be detected in front of body head generates deformation without motor so that ultrasound into
As probe is unaffected by the magnetic field；Langevin-type transducer makes piezoelectric material generate deformation by inverse piezoelectric effect, thus small volume may be used
With the weight for reducing the volume of ultrasound imaging probe, mitigating ultrasound imaging probe.
Description of the drawings
The features and advantages of the present invention can be more clearly understood by reference to attached drawing, attached drawing is schematically without that should manage
It solves to carry out any restrictions to the present invention, in the accompanying drawings：
Fig. 1 shows a kind of structure diagram of ultrasound imaging probe according to embodiments of the present invention；
Fig. 2 shows the structure diagrams of another ultrasound imaging probe according to embodiments of the present invention；
Fig. 3 shows that Langevin-type transducer drives the schematic diagram of ultrasound imaging probe longitudinal vibration；
Fig. 4 shows that Langevin-type transducer drives the schematic diagram of ultrasound imaging probe bending vibration；
Fig. 5 shows the longitudinal vibration of Langevin-type transducer and bending vibration schematic diagram；
Fig. 6 shows a kind of flow chart of elastograph imaging method according to embodiments of the present invention；
Fig. 7 shows the flow chart of another elastograph imaging method according to embodiments of the present invention；
Fig. 8 shows a kind of particular flow sheet of step S250；
Fig. 9 shows the schematic diagram of the first ultrasound echo signal and the second ultrasound echo signal；
Figure 10 shows another particular flow sheet of step S250；
Figure 11 shows the flow chart of another elastograph imaging method according to embodiments of the present invention；
Figure 12 shows ultrasound imaging probe to the side view of tissue emissions ultrasonic wave to be detected；
Figure 13 shows the schematic diagram of each predetermined inclination；
Figure 14 shows that the ultrasonic wave that ultrasound imaging probe is emitted can receive ultrasonic echo in tissue to be detected
Range vertical view；
Figure 15 shows the flow chart of another elastograph imaging method according to embodiments of the present invention；
Figure 16 shows that only there are one the schematic diagrames of shearing wave wave crest in tissue to be detected；
Figure 17 shows a kind of functional block diagrams of elastogram device according to embodiments of the present invention；
Figure 18 shows the functional block diagram of another elastogram device according to embodiments of the present invention；
Figure 19 is the hardware architecture diagram for showing elastogram equipment according to embodiments of the present invention.
Specific embodiment
Purpose, technical scheme and advantage to make the embodiment of the present invention are clearer, below in conjunction with the embodiment of the present invention
In attached drawing, the technical solution in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is
Part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, those skilled in the art are not having
All other embodiments obtained under the premise of creative work are made, shall fall within the protection scope of the present invention.
Embodiment one
An embodiment of the present invention provides a kind of ultrasound imaging probes, and as depicted in figs. 1 and 2, which includes
Main body 10, at least one ultrasonic transducer 12 and Langevin-type transducer 13.
Ultrasonic transducer 12 is arranged on the head of main body 10, can be a ultrasonic transducer or ultrasonic transduction
Device array, for emitting ultrasonic wave and receiving ultrasound echo signal.Langevin-type transducer 13 is arranged in main body 10, Langevin-type transducer
13 under the excitation of the first predetermined electrical signals can longitudinal vibration and driving vibrate before and after the head of main body 10.Wherein longitudinal vibration refers to Lan Jiewen
The front end of oscillator can be a longitudinal vibration or reciprocal longitudinal vibration towards or away from the rear end motion of Langevin-type transducer.It is front and rear
Vibration refers to the direction vibration according to Langevin-type transducer longitudinal vibration.
Above-mentioned ultrasound imaging probe vibrates before and after driving the head of main body using the longitudinal vibration pattern of Langevin-type transducer, can be with
Tissue to be detected is easily made to generate deformation and obtains ultrasonic echo information, before may be such that body head without motor
The tissue to be detected of side generates deformation, so that ultrasound imaging probe is unaffected by the magnetic field；Langevin-type transducer passes through inverse piezoelectricity
Effect makes piezoelectric material generate deformation, small volume, it is possible thereby to reduce the volume of ultrasound imaging probe, mitigate ultrasonic imaging spy
The weight of head.
Optionally, the Langevin-type transducer 13 in above-mentioned ultrasound imaging probe being capable of bending vibration under the excitation of the second predetermined electrical signals
And the head of main body 10 is driven to swing laterally.Wherein bending vibration refers to that the front end direction of Langevin-type transducer is rolled to each side.
The head for driving main body using the bending vibration pattern of Langevin-type transducer is swung laterally, so that being set to body head
Ultrasonic transducer ultrasonic wave can be sent to the tissue location to be detected in multiple orientation and receives ultrasonic echo, so as to logical
It crosses the ultrasonic transducer of one or less and obtains the ultrasonic imaging information to be detected organized in lastblock region, ultrasound can be increased
The visual field of energy converter.Multiple ultrasonic transducers need not be set on the ultrasound imaging probe, it is small volume, lighter.
Langevin-type transducer is a kind of component that can be vibrated under predetermined electrical signals excitation according to predetermined rule.For example,
The excitation of first predetermined electrical signals is lower for longitudinal vibration pattern, the i.e. up-down vibration as shown in Fig. 3 and Fig. 5 (a)；In the second predetermined electrical signals
Excitation is lower for bending vibration pattern, i.e. the horizontal swing as shown in Fig. 4 and Fig. 5 (b) or be another in the case where third predetermined electrical signals encourage
A kind of bending vibration pattern, i.e., the swing as shown in Fig. 5 (c).About the longitudinal vibration of Langevin-type transducer and bending vibration pattern, the prior art
Existing research, such as document《The Structural Dynamics finite element model of Langevin-type transducer》(Li Zhirong etc., SUZHOU VOCATIONAL UNIVERSITY are learned
Report, in March, 2013, the 1st phase of volume 24), the application is not herein to the specific of the specific form of Langevin-type transducer, longitudinal vibration and bending vibration
Control mode limits.
As a kind of optional embodiment of the present embodiment, as shown in Figure 1, main body 10 can include forepart 11, then it is blue outstanding
The front end of literary oscillator 13 is fixedly connected with the rear end of forepart 11.The rear end of Langevin-type transducer 13 can be fixedly installed, such as fixed
It is arranged on shell 14.
Alternatively, the optional embodiment arranged side by side as above-mentioned optional embodiment, as shown in Fig. 2, main body 10 can include
Forepart 11 and rear portion 15.The front end of Langevin-type transducer 13 is fixedly connected with the rear end of forepart 11, the rear end of Langevin-type transducer 13 with
The front end at rear portion 15 is fixedly connected.The rear end at rear portion 15 can be fixedly installed, such as be fixed on shell 14.
It should be added that the ultrasonic transducer in the application can also be using Langevin-type transducer as main body, ultrasound
Energy converter is arranged on the front end of Langevin-type transducer, and the rear end of Langevin-type transducer can be fixedly installed on the shell.
Embodiment two
Fig. 6 shows a kind of flow chart of elastograph imaging method according to embodiments of the present invention.This method can be by means of
Ultrasound imaging probe described in embodiment one is realized.As shown in fig. 6, this method comprises the following steps：
S110：The ultrasonic transducer that control is arranged on ultrasound imaging probe body head is ultrasonic towards tissue emissions to be detected
Wave and the first ultrasound echo signal for receiving Tissue reflectance to be detected.
The ultrasonic transducer 12 for being arranged on 10 head of ultrasound imaging probe main body can be a ultrasonic transducer, can also
It is ultrasound transducer array.
Step S110 obtains the first ultrasonic echo letter of Tissue reflectance to be detected before tissue to be detected is made to generate deformation
Number, it can be used as with reference to signal.
S120：Generate the excitation Langevin-type transducer longitudinal vibration of the first predetermined electrical signals, drive during Langevin-type transducer longitudinal vibration ultrasound into
It is made to generate deformation as the head of probe body acts on tissue to be detected.
50 in Fig. 1 and Fig. 2 be tissue to be detected, as shown in figure 3, when Langevin-type transducer longitudinal vibration drives the head of main body 10
It, can be so that tissue to be detected generates deformation when the head of main body 10 is close to tissue to be detected after front and rear vibration.
S130：The ultrasonic transducer that control is arranged on ultrasound imaging probe body head is ultrasonic towards tissue emissions to be detected
Wave and the second ultrasound echo signal for receiving Tissue reflectance to be detected.
S140：Elastogram information is determined according to the first ultrasound echo signal and the second ultrasound echo signal.
According to the first echo signal to be detected for organizing to reflect respectively before deformation is generated, after generation deformation, the second ultrasound
Echo-signal can obtain the response parameters such as displacement, strain, strain rate, the shearing velocity of wave propagation of tissue to be detected, and then estimate
The relative value of the properties of material mechanics such as Young's modulus, the Poisson's ratio of tissue to be detected is counted out as elastogram information, specific side
Method is referred to the prior art, and the application is not limited thereto.
Above-mentioned elastograph imaging method vibrates before and after driving the head of main body using the longitudinal vibration pattern of Langevin-type transducer, can be with
Tissue to be detected is easily made to generate deformation and obtains ultrasonic echo information, before may be such that body head without motor
The tissue to be detected of side generates deformation, so that ultrasound imaging probe is unaffected by the magnetic field；Langevin-type transducer passes through inverse piezoelectricity
Effect makes piezoelectric material generate deformation, small volume, it is possible thereby to reduce the volume of ultrasound imaging probe, mitigate ultrasonic imaging spy
The weight of head.
Embodiment three
Fig. 7 shows the flow chart of another elastograph imaging method according to embodiments of the present invention.This method can be by
It is realized in the ultrasound imaging probe described in embodiment one.As shown in fig. 7, this method comprises the following steps：
S210：The ultrasonic transducer that control is arranged on ultrasound imaging probe body head is ultrasonic towards tissue emissions to be detected
Wave and the first ultrasound echo signal for receiving Tissue reflectance to be detected.Refer to step S110.
S220：Generate the excitation Langevin-type transducer longitudinal vibration of the first predetermined electrical signals, drive during Langevin-type transducer longitudinal vibration ultrasound into
It is made to generate deformation as the head of probe body acts on tissue to be detected.Refer to step S120.
S230：The ultrasonic transducer that control is arranged on ultrasound imaging probe body head is ultrasonic towards tissue emissions to be detected
Wave and the second ultrasound echo signal for receiving Tissue reflectance to be detected.
S240：The ultrasonic transducer that control is arranged on ultrasound imaging probe body head is ultrasonic towards tissue emissions to be detected
Wave and the third ultrasound echo signal for receiving Tissue reflectance to be detected.
S250：Shearing wave is determined according to the first ultrasound echo signal, the second ultrasound echo signal, third ultrasound echo signal
Spread speed, shearing wave generates the waveform propagated from deformation position to vertical-depth after deformation for tissue to be detected.
As shown in Fig. 3 (d), after the surface undergoes deformation of tissue to be detected, the internal shearing wave that just generates is with the shape of spherical surface
Formula is propagated outward since DEFORMATION POINTS.
For same predetermined inclination position, using the first ultrasound echo signal as reference, according to the first ultrasound echo signal and
Second ultrasound echo signal can determine the shearing wave crest location of the first moment t1；Using the first ultrasound echo signal as reference,
The shearing wave crest location of the second moment t2 can be determined according to the first ultrasound echo signal and third ultrasound echo signal.According to
The time difference of the displacement of wave crest, t2 moment and t1 moment is the spread speed that can determine shearing wave.
S260：The Young's modulus of tissue to be detected is determined according to the spread speed of shearing wave.
Relationship between Young's modulus and shearing wave is：E=3* ρ * Vs 2.Wherein, E is Young's modulus；ρ is tissue to be detected
Density (kg/m3), it is constant；VsSpread speed for shearing wave.It it can be seen that can be true according to the spread speed of shearing wave
The Young's modulus of fixed tissue to be detected.
As a kind of optional embodiment of the present embodiment, as shown in figure 13, step S250 include S251, S252, S253,
S254, S255 and S256.
S251：Determine the primary peak of shearing wave second according to the first ultrasound echo signal and the second ultrasound echo signal
The serial number n of sampled point is corresponded in ultrasound echo signal1。
As shown in figure 9, obtain ultrasound echo signal with predetermined sampling frequency, in ultrasound echo signal, sampling instant is earlier
Ultrasonic echo amplitude corresponds to tissue shallower in tissue to be detected, and the later ultrasonic echo amplitude of sampling instant corresponds to be checked
Survey tissue deeper in tissue.
Step S251 can repeatedly choose the first ultrasound echo signal and the second ultrasound echo signal identical and/or adjacent
Predetermined amount of time in signal (window function may be used to be chosen, window function length is predetermined amount of time), calculate selected
The first ultrasound echo signal and the cross correlation value of the second ultrasound echo signal taken.When cross correlation value is less than predetermined value, really
Determine serial number corresponding sampling in the second ultrasound echo signal as wave crest of sampled point in the corresponding predetermined amount of time of cross correlation value
The serial number of point.
For example, as shown in figure 9, can by hanning windows choose the A2-A1 periods in the first ultrasound echo signal with
Second ultrasound echo signal calculates cross correlation value；When then choosing the first ultrasound echo signal in the A2-A1 periods with B2-B1
Between the second ultrasound echo signal in section calculate cross correlation value namely the window of the first ultrasound echo signal is constant, will the second surpass
The window of sound echo-signal moves backward.
Cross-correlation calculation formula can be：
Wherein, CXX(N) it is cross correlation value, set of the N for sampled point in predetermined amount of time, RF1(n) it is the first ultrasonic echo
In signal in the set N of sampled point n-th of sampled point amplitude, RF2(n) set for sampled point in the second ultrasound echo signal
The amplitude of n-th of sampled point in N,All sampled points correspond in set N for sampled point in the first ultrasound echo signal
The average value of amplitude,The flat of amplitude is corresponded to for all sampled points in the set N of sampled point in the second ultrasound echo signal
Mean value.
Under normal conditions, if tissue to be detected is not made to generate deformation, the first ultrasound echo signal and the second ultrasonic echo
Signal in theory should be identical, and the cross correlation value in same time period should be 1 (or to be influenced, less than 1 by other factors
But close to 1).By shearing wave action, the tissue to be detected of shearing wave crest location is squeezed on the second ultrasound echo signal, wave
The ultrasound echo signal of peak position is usually smaller with cross correlation value of first ultrasound echo signal in identical or time adjacent segments,
That is the two difference is larger.The application is made a reservation for by the first ultrasound echo signal and the second ultrasound echo signal in identical or adjacent
The cross correlation value of period can quickly determine the corresponding position of shearing wave wave crest.
S252：Determine the secondary peak of shearing wave in third according to the first ultrasound echo signal and third ultrasound echo signal
The serial number n of sampled point is corresponded in ultrasound echo signal2。
Step S252 can repeatedly choose the first ultrasound echo signal and third ultrasound echo signal identical and/or adjacent
Predetermined amount of time in signal, calculate the cross-correlation of the first ultrasound echo signal being selected and third ultrasound echo signal
Value.When cross correlation value is less than predetermined value, determine the serial number of sampled point in the corresponding predetermined amount of time of cross correlation value as wave
Peak corresponds to the serial number of sampled point in third ultrasound echo signal.Specifically refer to step S251.
S253：Obtain the spread speed v of ultrasonic wave0, ultrasonic echo sample frequency f.
S254：Primary peak is calculated to the displacement s of secondary peak：
S255：Obtain the time interval t for receiving the second ultrasonic echo with receiving third ultrasonic echo1。
S256：Calculate the spread speed of shearing wave：
As the optional embodiment arranged side by side of above-mentioned optional embodiment, as shown in Figure 10, step S250 can also be wrapped only
Include S257, S258, S259.
S257：Determine the primary peak of shearing wave second according to the first ultrasound echo signal and the second ultrasound echo signal
The serial number n of sampled point is corresponded in ultrasound echo signal1。
S258：Obtain the spread speed v of ultrasonic wave0, ultrasonic echo sample frequency f.
S259：Calculate displacement s of the shearing wave from DEFORMATION POINTS to primary peak：
S2510：Obtaining makes tissue deformation to be detected at the time of terminate with receiving the time interval at the second ultrasonic echo moment
t2。
S2511：Calculate the spread speed of shearing wave：
Above method embodiment gives the position determined according to the ultrasound echo signal of a certain position of tissue to be detected
The method of elastogram information put.
If however, by the way that a ultrasonic transducer on ultrasound imaging probe is set to obtain one piece of area of tissue to be detected one by one
It is longer then to expend the time for the elastic information of difference position in domain.Existing way is often corresponded to using ultrasound transducer array to be treated
It detects the different location transmitting of tissue or receives ultrasonic echo, so as to obtain the elastic information in one piece of region.However, existing side
Formula requirement ultrasound imaging probe on must be provided with multiple ultrasonic transducers, so as to cause ultrasound imaging probe volume it is larger, compared with
It is heavy.For this purpose, Langevin-type transducer bending vibration may be used to increase the visual field of ultrasonic transducer so that need not on ultrasound imaging probe
Multiple ultrasonic transducers are set, it is small volume, lighter.Such as the following example four or embodiment five may be used to realize.
Example IV
Figure 11 shows the flow chart of another elastograph imaging method according to embodiments of the present invention, and this method can be by
It is realized in the ultrasound imaging probe of embodiment one.As shown in figure 11, this method comprises the following steps：
S310：It generates the first predetermined electrical signals and encourages the Langevin-type transducer being arranged in ultrasound imaging probe main body according to pre-
Determine direction transverse direction bending vibration, the ultrasonic transducer of ultrasound imaging probe body head is driven during Langevin-type transducer transverse direction bending vibration
It is swung laterally in predetermined inclination angular region.
Figure 12 shows ultrasound imaging probe to the side view of tissue emissions ultrasonic wave to be detected, and Figure 13 shows each pre-
The schematic diagram at constant inclination angle.Arrow OA and OB are represented respectively in the amplitude peak of both sides when Langevin-type transducer is swung laterally, such as can
Using the angle theta relative to the position (position shown in OO ' in Figure 12) when not swinging as 15 °, AA ', BB ' are respectively that ultrasonic signal exists
Propagation path in tissue to be detected.
S320：Control ultrasonic transducer when being rocked at least one predetermined inclination towards tissue emissions ultrasonic wave to be detected
And receive the first ultrasound echo signal of Tissue reflectance to be detected.
Figure 14 shows that the ultrasonic wave that ultrasound imaging probe is emitted can receive ultrasonic echo in tissue to be detected
Range vertical view.Wherein, A ' B ' drive ultrasonic transducer ultrasonic transducer in bending vibration on A ' B ' directions for Langevin-type transducer
The range of ultrasonic echo can be received.It, can be towards treating in any angle when Langevin-type transducer is in A ' B ' direction bending vibrations
Detection tissue emissions ultrasonic wave simultaneously receives ultrasonic echo, then can obtain the ultrasound echo signal at any point on straight line A ' B ',
And then the elastogram information of any position of tissue to be detected on the straight line can be obtained.
S330：The elastogram letter of tissue location to be detected according to corresponding to the first ultrasound echo signal determines predetermined inclination
Breath.Refer to step S140.
As shown in figure 14, C ' D ' drive ultrasonic transducer ultrasonic transducer in bending vibration on C ' D ' directions for Langevin-type transducer
The range of ultrasonic echo can be received, E ' F ' drive ultrasonic transducer ultrasonic in bending vibration on E ' F ' directions for Langevin-type transducer
Energy converter can receive the range ... of ultrasonic echo it can be seen that theoretically, in the situation that predetermined inclination angular region is constant
Under, the subregional tissue to be detected of shadow part in Figure 14 can be obtained if the lateral bending vibration direction of transformation Langevin-type transducer and is taken up an official post
It anticipates the ultrasound echo signal of position, and then the elastogram information of tissue to be detected in the region can be obtained.
Above-mentioned elastograph imaging method, the head for driving main body using the bending vibration pattern of Langevin-type transducer are swung laterally, so as to
The ultrasonic transducer for being set to body head is allowd to send ultrasonic wave to the tissue location to be detected in multiple orientation and receive
Ultrasonic echo, so as to obtained by the ultrasonic transducer of one or less elasticity in tissue lastblock region to be detected into
As information, increase the visual field of ultrasonic transducer.Multiple ultrasonic transducers need not be set on the ultrasound imaging probe, small volume,
It is lighter.
Embodiment five
Figure 15 shows the flow chart of another elastograph imaging method according to embodiments of the present invention, and this method can be by
It is realized in the ultrasound imaging probe of embodiment one.As shown in figure 15, this method comprises the following steps：
S410：It generates the first predetermined electrical signals and encourages the Langevin-type transducer being arranged in ultrasound imaging probe main body according to pre-
Determine direction transverse direction bending vibration, the ultrasonic transducer of ultrasound imaging probe body head is driven during Langevin-type transducer transverse direction bending vibration
It is swung laterally in predetermined inclination angular region.Refer to step S310.
S420：Control ultrasonic transducer when being rocked at least one predetermined inclination towards tissue emissions ultrasonic wave to be detected
And receive the first ultrasound echo signal of Tissue reflectance to be detected.Refer to step S320.
S430：Generate the excitation Langevin-type transducer longitudinal vibration of the first predetermined electrical signals, drive during Langevin-type transducer longitudinal vibration ultrasound into
It is once made to generate deformation as the head of probe body is spaced pressing tissue to be detected at predetermined time intervals.
It should be added that the mode that above-mentioned steps S430 makes tissue to be detected generate deformation is not limited to using orchid
Outstanding text oscillator longitudinal vibration drives the mode of body head longitudinal vibration, and motor can also be used to drive body head longitudinal vibration or also may be used
With using the pressing of other devices or Manual press.
As a kind of mode of texturing of step S430, it can also only press tissue to be detected once, its is made to generate a shape
Become.Correspondingly, only there are one wave crests for the shearing wave in tissue to be detected, then attenuation just can not obtain a wave crest accordingly later in short term
Take shear-wave velocity.Figure 16 shows that wherein solid-line curve represents only there are one the schematic diagram of shearing wave wave crest in tissue to be detected
The crest location at current time, imaginary curve represent the crest location of last time.
For this purpose, each predetermined time interval pressing tissues to be detected of above-mentioned steps S430 once make it generate deformation so that
Shearing wave in tissue to be detected can have multiple wave crests, and duration of the shearing wave in tissue to be detected is longer, and extension is cut
The detection time of wave is cut, convenient for obtaining the ultrasound echo signal of multiple positions during follow-up Langevin-type transducer bending vibration.Figure 12 and
Figure 14 shows the schematic diagram for having multiple shearing wave wave crests in tissue to be detected, and wherein solid-line curve represents the wave crest position at current time
It puts, imaginary curve represents the wave trough position at current time.
S440：Control ultrasonic transducer when being rocked to the predetermined inclination again towards tissue emissions ultrasonic wave to be detected simultaneously
Receive the second ultrasound echo signal of Tissue reflectance to be detected.
Ultrasonic propagation velocity is far longer than shearing velocity of wave propagation.By taking the tissue to be detected of 20cm depth as an example, shearing
The spread speed of wave is about 5m/s, and the Persistent Excitation time of shearing wave is set as 0.2/5=0.04s.Ultrasonic propagation velocity is about
1540m/s, ultrasonic wave, which emits and returns to primary maximum detection time, is：0.2*2/1540=2.5*10-4s.Langevin-type transducer
Bending vibration working frequency is about 65Hz, and -15 ° of bending angle range~15 °, (15 ° are rocked to from -15 ° as half period) is at the angle
(every 2 ° emit and acquire one the ultrasonic signal for acquiring altogether on 15 straight lines (each predetermined inclination corresponds to straight line) in the range of degree
Secondary ultrasonic signal), the sweep time on each straight line is 1/65/2/15=5.13*10-4S can meet on the same line
Transmitting and receive 2 ultrasonic signals.
With reference to Figure 13, it is assumed that the inclination angle of Langevin-type transducer transverse direction bending vibration is θ, emits a ultrasonic wave simultaneously every △ angles
Ultrasonic echo is received, then time of ultrasonic wave that (being half period from-θ to+θ) emits in the half period of Langevin-type transducer bending vibration
Number isSweep time on each straight line isAssuming that the depth of tissue to be detected is H, the biography of ultrasonic wave
Speed is broadcast as vu, then ultrasonic wave, which emits and returns to primary maximum detection time, isIt can be seen that it need to only design satisfactionIt can meet and emit a ultrasonic wave every △ angles and receive ultrasonic echo；If you need to every △ angles
Transmitting n times ultrasonic wave simultaneously receives ultrasonic echo, then needs to design
S450：It is to be detected according to corresponding to the first ultrasound echo signal and the second ultrasound echo signal determine the predetermined inclination
The spread speed of the shearing wave of tissue location, shearing wave is propagates from deformation position to vertical-depth after tissue generation deformation to be detected
Waveform.Refer to step S250.
S460：The Young mould of tissue location to be detected according to corresponding to the spread speed of shearing wave determines the predetermined inclination
Amount.Refer to step S260.
Embodiment six
Figure 17 shows a kind of functional block diagram of elastogram device according to embodiments of the present invention, which can be used for
Elastograph imaging method described in realization embodiment two or embodiment three or its any one optional embodiment.Such as Figure 17 institutes
Show, which includes the first control unit 10, the first exciting unit 20, the second control unit 30 and determination unit 40.
First control unit 10 is arranged on the ultrasonic transducer of ultrasound imaging probe body head towards to be checked for controlling
It surveys tissue emissions ultrasonic wave and receives the first ultrasound echo signal of Tissue reflectance to be detected.
First exciting unit 20 encourages Langevin-type transducer longitudinal vibration, Langevin-type transducer longitudinal vibration for generating the first predetermined electrical signals
When drive ultrasound imaging probe main body head act on it is to be detected tissue make its generate deformation.
Second control unit 30 is arranged on the ultrasonic transducer of ultrasound imaging probe body head towards to be checked for controlling
It surveys tissue emissions ultrasonic wave and receives the second ultrasound echo signal of Tissue reflectance to be detected.
Determination unit 40 is used to determine elastogram information according to the first ultrasound echo signal and the second ultrasound echo signal.
Above-mentioned elastogram device enables to ultrasound imaging probe to be unaffected by the magnetic field, and can reduce ultrasonic imaging spy
The volume of head, the weight for mitigating ultrasound imaging probe.Specifically refer to embodiment two.
As a kind of optional embodiment of the present embodiment, as shown in figure 18, determination unit 40 includes first and determines that son is single
41 and second determination subelement 42 of member.First determination subelement 41 is used for according to the first ultrasound echo signal and the second ultrasonic echo
Signal determines the spread speed of shearing wave, and shearing wave is to be propagated after tissue to be detected generates deformation from deformation position to vertical-depth
Waveform.Second determination subelement 42 is used to determine the Young's modulus of tissue to be detected according to the spread speed of shearing wave.
As a kind of optional embodiment of the present embodiment, as shown in figure 18, which further includes third control unit 50,
For controlling the ultrasonic transducer for being arranged on ultrasound imaging probe body head towards tissue emissions ultrasonic wave to be detected and receiving
The third ultrasound echo signal of Tissue reflectance to be detected.
First determination subelement 41 includes third determination subelement 411, the 4th determination subelement 412, first obtains son list
First 413, first computation subunit 414, second obtains 415 and second computation subunit 416 of subelement.Third determination subelement
411 are used to determine that the primary peak of shearing wave is returned in the second ultrasound according to the first ultrasound echo signal and the second ultrasound echo signal
The serial number n1 of sampled point is corresponded in wave signal.4th determination subelement 412 is used to be surpassed according to the first ultrasound echo signal and third
Sound echo-signal determines that the secondary peak of shearing wave corresponds to the serial number n of sampled point in third ultrasound echo signal2.First obtains
Subelement 413 is used to obtain the spread speed v of ultrasonic wave0, ultrasonic echo sample frequency f.
First computation subunit 414 is used to calculate primary peak to the displacement s of secondary peak：
Second obtains subelement 415 for obtaining the time interval t for receiving the second ultrasonic echo and receiving third ultrasonic echo1.Second
Computation subunit 416 is used to calculate the spread speed of shearing wave：
Optionally, as shown in figure 18, third determination subelement 411 includes third computation subunit and the 5th determining son is single
Member.Third computation subunit is for repeatedly the first ultrasound echo signal of selection and the second ultrasound echo signal in identical and/or phase
Signal in adjacent predetermined amount of time calculates the cross-correlation of the first ultrasound echo signal being selected and the second ultrasound echo signal
Value.5th determination subelement is used to, when cross correlation value is less than predetermined value, determine in the corresponding predetermined amount of time of cross correlation value
The serial number of sampled point corresponds to the serial number of sampled point as wave crest in the second ultrasound echo signal.
Optionally, as shown in figure 18, the 4th determination subelement 412 includes third computation subunit and the 5th determining son is single
Member.Third computation subunit is for repeatedly the first ultrasound echo signal of selection and third ultrasound echo signal in identical and/or phase
Signal in adjacent predetermined amount of time calculates the cross-correlation of the first ultrasound echo signal being selected and third ultrasound echo signal
Value.5th determination subelement is used to, when cross correlation value is less than predetermined value, determine in the corresponding predetermined amount of time of cross correlation value
The serial number of sampled point corresponds to the serial number of sampled point as wave crest in third ultrasound echo signal.
Figure 19 is the hardware configuration signal of the elastogram equipment provided in an embodiment of the present invention for performing elastograph imaging method
Figure, as shown in figure 19, the equipment include ultrasound imaging probe 1910, display 1920, one or more processors 1930 and
Memory 1940, in Figure 19 by taking a processor 1930 as an example.
Ultrasound imaging probe 1910, display 1920, processor 1930 and memory 1940 can by bus or its
He connects mode, in Figure 19 for being connected by bus.
Ultrasound imaging probe 1910 can be described in embodiment one, for surpassing to tissue emissions ultrasonic wave to be detected and acquisition
Sound echo-signal.Display 1920 is used to show the elastogram information of tissue to be detected.
Processor 1930 can be central processing unit (Central Processing Unit, CPU).Processor 1930 is also
Can be other general processors, digital signal processor (Digital Signal Processor, DSP), special integrated electricity
Road (App1ication Specific Integrated Circuit, ASIC), field programmable gate array (Field-
Programmable Gate Array, FPGA) either other programmable logic device, discrete gate or transistor logic,
The combination of the chips such as discrete hardware components or above-mentioned all kinds of chips.General processor can be microprocessor or the processing
Device can also be any conventional processor etc..
It should be added that above-mentioned processor 1930 can be set to the outside of ultrasound imaging probe 1910, also may be used
To be set to the inside of ultrasound imaging probe 1910.
Memory 1940 be used as a kind of non-transient computer readable storage medium storing program for executing, available for store non-transient software program,
Non-transient computer executable program and module, as the corresponding program instruction of elastograph imaging method in the embodiment of the present application/
Module is (for example, the first control unit 10, the first exciting unit 20, the second control unit 30 and determination unit shown in attached drawing 17
40).Processor 1930 is stored in non-transient software program, instruction and module in memory 1940 by operation, so as to hold
Above method embodiment elastograph imaging method is realized in the various function application of row server and data processing.
Memory 1940 can include storing program area and storage data field, wherein, storing program area can store operation system
System, the required application program of at least one function；Storage data field can store making for the processing unit that is operated according to list items
With data created etc..In addition, memory 1940 can include high-speed random access memory, non-transient deposit can also be included
Reservoir, for example, at least a disk memory, flush memory device or other non-transient solid-state memories.In some embodiments
In, memory 1940 is optional including relative to the remotely located memory of processor 1930, these remote memories can pass through
The processing unit that network connection is operated to list items.The example of above-mentioned network includes but not limited to internet, intranet, office
Domain net, mobile radio communication and combinations thereof.
One or more of modules are stored in the memory 1940, when by one or more of processors
During 1930 execution, such as Fig. 6, method shown in Fig. 10 are performed.
The said goods can perform the method that the embodiment of the present invention is provided, and has the corresponding function module of execution method and has
Beneficial effect.The not technical detail of detailed description in the present embodiment, for details, reference can be made to as in Fig. 6, embodiment shown in Fig. 10
Associated description.
The embodiment of the present invention additionally provides a kind of non-transient computer storage medium, and the computer storage media is stored with
Computer executable instructions, the computer executable instructions can perform the elastograph imaging method in above-mentioned any means embodiment.
Wherein, the storage medium can be magnetic disc, CD, read-only memory (Read-Only Memory, ROM), random storage
Memory body (Random Access Memory, RAM), flash memory (Flash Memory), hard disk (Hard Disk
Drive, abbreviation：) or solid state disk (Solid-State Drive, SSD) etc. HDD；The storage medium can also include above-mentioned
The combination of the memory of type.
It is that can lead to it will be understood by those skilled in the art that realizing all or part of flow in above-described embodiment method
It crosses computer program and is completed to instruct relevant hardware, the program can be stored in a computer read/write memory medium
In, the program is when being executed, it may include such as the flow of the embodiment of above-mentioned each method.Wherein, the storage medium can be magnetic
Dish, CD, read-only memory (ROM) or random access memory (RAM) etc..
Although being described in conjunction with the accompanying the embodiment of the present invention, those skilled in the art can not depart from the present invention
Spirit and scope in the case of various modifications and variations can be made, such modifications and variations are each fallen within by appended claims institute
Within the scope of restriction.
Claims (10)
1. a kind of elastograph imaging method, which is characterized in that including：
Control is arranged on the ultrasonic transducer of ultrasound imaging probe body head towards tissue emissions ultrasonic wave to be detected and receives
First ultrasound echo signal of the Tissue reflectance to be detected；
It generates the first predetermined electrical signals and encourages the Langevin-type transducer longitudinal vibration, when Langevin-type transducer longitudinal vibration drives ultrasonic imaging
The head of probe body, which acts on the tissue to be detected, makes it generate deformation；
The ultrasonic transducer that control is arranged on the ultrasound imaging probe body head is ultrasonic towards the tissue emissions to be detected
Wave and the second ultrasound echo signal for receiving the Tissue reflectance to be detected；
Elastogram information is determined according to first ultrasound echo signal and second ultrasound echo signal.
2. elastograph imaging method according to claim 1, which is characterized in that described according to first ultrasound echo signal
The step of elastogram information being determined with second ultrasound echo signal, including：
The spread speed of shearing wave is determined according to first ultrasound echo signal and second ultrasound echo signal, it is described to cut
It cuts wave and generates the waveform propagated after deformation from deformation position to vertical-depth for tissue to be detected；
The Young's modulus of tissue to be detected is determined according to the spread speed of the shearing wave.
3. elastograph imaging method according to claim 2, which is characterized in that the control is arranged on the ultrasonic imaging and visits
The ultrasonic transducer of head body head towards the tissue emissions ultrasonic wave to be detected and receives the Tissue reflectance to be detected
After the step of second ultrasound echo signal, further include：The ultrasound that control is arranged on the ultrasound imaging probe body head is changed
Can device towards the tissue emissions ultrasonic wave to be detected and receive the third ultrasound echo signal of the Tissue reflectance to be detected；
The spread speed that shearing wave is determined according to first ultrasound echo signal and second ultrasound echo signal
Step includes：
Determine that the primary peak of the shearing wave exists according to first ultrasound echo signal and second ultrasound echo signal
The serial number n of sampled point is corresponded in second ultrasound echo signal1；
Determine that the secondary peak of the shearing wave exists according to first ultrasound echo signal and the third ultrasound echo signal
The serial number n of sampled point is corresponded in the third ultrasound echo signal2；
Obtain the spread speed v of ultrasonic wave0, ultrasonic echo sample frequency f；
The primary peak is calculated to the displacement s of the secondary peak：
Obtain the time interval t for receiving second ultrasonic echo with receiving the third ultrasonic echo1；
Calculate the spread speed of the shearing wave：
4. elastograph imaging method according to claim 3, which is characterized in that according to first ultrasound echo signal and
X ultrasound echo signals determine that the wave crest of the shearing wave corresponds to the step of the serial number of sampled point in the X ultrasound echo signal
Suddenly, including：
First ultrasound echo signal and the X ultrasound echo signal are repeatedly chosen in identical and/or adjacent pre- timing
Between signal in section, calculate the cross correlation value of the first ultrasound echo signal being selected and X ultrasound echo signal；
When cross correlation value is less than predetermined value, determine that the serial number of sampled point in the corresponding predetermined amount of time of the cross correlation value is made
The serial number of sampled point is corresponded in the X ultrasound echo signal for wave crest；
The X ultrasound echo signal includes the second ultrasound echo signal or third ultrasound echo signal.
5. a kind of elastogram device, which is characterized in that including：
First control unit is arranged on the ultrasonic transducer of ultrasound imaging probe body head towards tissue to be detected for controlling
Transmitting ultrasonic wave and the first ultrasound echo signal for receiving the Tissue reflectance to be detected；
First exciting unit encourages the Langevin-type transducer longitudinal vibration, the Langevin-type transducer for generating the first predetermined electrical signals
The head of ultrasound imaging probe main body is driven to act on the tissue to be detected during longitudinal vibration makes it generate deformation；
Second control unit, for the ultrasonic transducer for being arranged on the ultrasound imaging probe body head to be controlled to be treated described in
Detection tissue emissions ultrasonic wave and the second ultrasound echo signal for receiving the Tissue reflectance to be detected；
Determination unit, for determining that elastogram is believed according to first ultrasound echo signal and second ultrasound echo signal
Breath.
6. a kind of ultrasound imaging probe, which is characterized in that including：
Main body；
At least one ultrasonic transducer is arranged on the head of the main body, for emitting ultrasonic wave and receiving ultrasound echo signal；
Langevin-type transducer, setting is on the body；The Langevin-type transducer being capable of longitudinal vibration under the excitation of the first predetermined electrical signals
And drive the head of the main body is front and rear to vibrate.
7. ultrasound imaging probe according to claim 6, which is characterized in that the main body includes forepart, the Lan Jiewen
The front end of oscillator is fixedly connected with the rear end of the forepart；Alternatively, the main body includes：
Forepart, the front end of the Langevin-type transducer are fixedly connected with the rear end of the forepart；
Rear portion, the rear end of the Langevin-type transducer are fixedly connected with the front end at the rear portion.
8. ultrasound imaging probe according to claim 6, which is characterized in that described under the excitation of the second predetermined electrical signals
Langevin-type transducer bending vibration and can drive the head of the main body to swing laterally under the excitation of the second predetermined electrical signals.
9. a kind of elastogram equipment, which is characterized in that including：Ultrasound imaging probe, display, memory and processor, institute
It states and connection is communicated between ultrasound imaging probe, the display, the memory and the processor, in the memory
Computer instruction is stored with, the processor is by performing the computer instruction, so as to the bullet described in perform claim requirement 1-4
Property imaging method.
10. a kind of computer readable storage medium, which is characterized in that the computer-readable recording medium storage has computer to refer to
It enables, the computer instruction is used to make the elastograph imaging method described in the computer perform claim requirement 1-4.
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