CN108007870A - A kind of skin neoplasin imaging device - Google Patents
A kind of skin neoplasin imaging device Download PDFInfo
- Publication number
- CN108007870A CN108007870A CN201711151719.5A CN201711151719A CN108007870A CN 108007870 A CN108007870 A CN 108007870A CN 201711151719 A CN201711151719 A CN 201711151719A CN 108007870 A CN108007870 A CN 108007870A
- Authority
- CN
- China
- Prior art keywords
- plane mirror
- skin neoplasin
- focal length
- sample stage
- polarizer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/21—Polarisation-affecting properties
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
The present invention relates to a kind of skin neoplasin imaging device, including the semiconductor laser that centre wavelength is 650nm, the convex lens, the polarizer and in the tilted-putted plane mirror of 45° angle that concavees lens, focal length that focal length is 20mm are 80mm are equipped with its front end light path successively, the lens and charge coupling device that the top of the plane mirror is equipped with analyzer successively, focal length is 60mm, the lower section of the plane mirror is equipped with sample stage and extinction plate successively, and the sample stage can be three-dimensional mobile relative to extinction plate；The polarizer, analyzer and charge coupling device are electrically connected with computer respectively.The present invention realizes the polarization intensity of skin neoplasin pathological tissues, the angle of polarization, polarization degree information by controlling analyzer and the polarizer, accurate imaging can be carried out in skin neoplasin lesion early stage, so as to obtain the skin neoplasin organizational information of comprehensive and abundant, structure is novel, imaging clearly, high resolution, imaging are accurate, the time is saved, the evolution of sample stage is flexible.
Description
Technical field
The invention belongs to Medical Instruments technical field, and in particular to a kind of skin neoplasin imaging device.
Background technology
With the enhancing of people's health consciousness and the increase of advanced detection means, the melanoma cases that China makes a definite diagnosis out
It is being continuously increased, is about being increased with annual 3% to 8% speed.In addition, as environmental pollution aggravates, ultraviolet irradiation amount day
Benefit increase, also increases the risk of Chinese population suffering from skin melanoma.The World Health Organization (WHO)《World's cancer report
Accuse》Indication, the following several years will be the global skin neoplasin patient time occurred frequently, and newly-increased cancer patient's number is up to every year in the whole world
15000000 people, die of cancer occurrence numbers more than 600 ten thousand, the incidence to the year two thousand twenty global range Malignant skin tumor will increase again
50%.Early diagnosis, early treatment are effective most effectual ways for curing malignant mela noma.According to statistics, diagnosis is made in early days and is controlled
The probability that the patient for the treatment of is survived 5 years is 95%, and the probability that otherwise patient is survived 5 years is only 50%.Data shows that skin neoplasin is suffered from
The survival period of person depends directly on state of an illness during diagnosis, early diagnosis and therapy can fully recover about 1/3rd patient, and face
The patient that bed skin neoplasin image checking is found often has can not be restored in cancer middle and advanced stage, therefore, studies cutaneum carcinoma
Disease technique for detection has very important significance.
At present, the skin neoplasin imaging device occurred both at home and abroad uses polarization imaging method more, it is by varying different inclined
Shake to obtain the polarization information of skin histology, since polarization information also has polarization intensity and polarization angle information, polarization imaging method
It is difficult to the comprehensive polarization information of life assemblage is obtained, and its ray machine assembling structure is unstable, can produce in use
Very big imaging deviation, has significant limitation.
The content of the invention
To solve the above problems, it is an object of the invention to provide a kind of skin neoplasin imaging device, have imaging clearly,
The characteristics of being imaged accurate, saving time, abundant information, small imaging deviation.
To achieve the above object, the technical solution taken of the present invention is：A kind of skin neoplasin imaging device, including middle cardiac wave
The semiconductor laser of a length of 650nm, it is the convex of 80mm to be equipped with concavees lens, focal length that focal length is 20mm in its front end light path successively
Lens, the polarizer and in the tilted-putted plane mirror of 45° angle, the top of the plane mirror is equipped with analyzer successively, focal length is
The lens and charge coupling device of 60mm, the lower section of the plane mirror are equipped with sample stage and extinction plate successively, the sample stage
Can be three-dimensional mobile relative to extinction plate；The polarizer, analyzer and charge coupling device are electrically connected with computer respectively.
Wherein, the extinction plate is equipped with sliding slot, upright slide rail is slidably equipped with the sliding slot, the sample stage is up and down reciprocatingly
It is slidedly arranged on upright slide rail.
Preferably, the sliding slot includes a horizontal concrete chute and a plurality of longitudinal chute to intersect vertically with horizontal concrete chute.
Wherein, the plane mirror by generally having plated anti-reflection film, half plated the eyeglass of Anti-reflective coating and formed.
Compared with prior art, the present invention has the advantages that：The present invention by control analyzer and the polarizer come
Realize the polarization intensities of skin neoplasin pathological tissues, the angle of polarization, polarization degree information, can be carried out in skin neoplasin lesion early stage accurate
Really imaging, so as to obtain the skin neoplasin organizational information of comprehensive and abundant, structure is novel, imaging clearly, high resolution, and imaging is accurate
Really, the time is saved, the evolution of sample stage is flexible.
Brief description of the drawings
Fig. 1 is the structure diagram of the embodiment of the present invention one；
Fig. 2 is extinction plate and the structure diagram after upright slide rail assembling in embodiment one.
Description of reference numerals：1st, semiconductor laser；2nd, concavees lens；3rd, convex lens；4th, the polarizer；5th, plane mirror；50th, increase
Head film；51st, Anti-reflective coating；6th, analyzer；7th, lens；8th, charge coupling device；9th, sample stage；10th, extinction plate；11st, computer；12、
Upright slide rail.
Embodiment
To make the technical problem to be solved in the present invention, technical solution and advantage clearer, below in conjunction with attached drawing and tool
Body embodiment is described in detail.
Refer to shown in Figure of description 1 and attached drawing 2, the present invention is a kind of skin neoplasin imaging device, including middle cardiac wave
The semiconductor laser 1 of a length of 650nm, it is 80mm's to be equipped with concavees lens 2, focal length that focal length is 20mm in its front end light path successively
Convex lens 3, the polarizer 4 and in the tilted-putted plane mirror 5 of 45° angle, the top of the plane mirror 5 are equipped with analyzer 6, burnt successively
Away from the lens 7 and charge coupling device 8 for 60mm, the lower section of the plane mirror 5 is equipped with sample stage 9 and extinction plate 10 successively,
The polarizer 4, analyzer 6 and charge coupling device 8 are electrically connected with computer 11 respectively.
The plane mirror 5 is by generally having plated anti-reflection film 50, half has been plated the eyeglass of Anti-reflective coating 51 and formed.
The extinction plate 10 is equipped with sliding slot 100, it includes a horizontal concrete chute and a plurality of intersects vertically with horizontal concrete chute
Longitudinal chute.Upright slide rail 12 is slidably equipped with the sliding slot 100, the sample stage 10 is up and down reciprocatingly slidedly arranged on upright slide rail 12
On, by said structure, the sample stage 9 can be three-dimensional mobile relative to extinction plate 10.
The present invention operation principle be：The incident light for the 6mm sizes that the semiconductor laser that centre wavelength is 650nm produces
Concavees lens first by focal length for 20mm, then collimated light beam is become for 80mm convex lenses by focal length, then pass through the polarizer
The polarised light of certain orientation is formed, it is then tilted-putted with plane mirror anti-reflection and that increasing is anti-by 45° angle again, adjust sample
Position of the platform on extinction plate, makes the skin neoplasin diseased region on parallel polarized light vertical irradiation sample stage, in vertical sample
The direction on surface, the backscattering optical fiber for the different polarization states that sample returns pass through analyzer, it is allowed to determine the scattering of polarization state
Pipe passes through, and then again by the lens 8 that focal length is 60nm, last charge coupling device is collected information and stored on computers, its
The middle polarizer and analyzer set the polarised light of different polarization states by computer.
Embodiment above is only the preferred embodiment of this creation, all in this wound not to limit this creation
Any modification, equivalent substitution, improvement and etc. done within the spirit and principle of work, should be included in this creation protection domain it
It is interior.
Claims (4)
- A kind of 1. skin neoplasin imaging device, it is characterised in that the semiconductor laser (1) including centre wavelength for 650nm, its The concavees lens (2), the convex lens (3) that focal length is 80mm, the polarizer (4) and be in that focal length is 20mm are equipped with the light path of front end successively The tilted-putted plane mirror of 45° angle (5), the top of the plane mirror (5) is successively the saturating of 60mm equipped with analyzer (6), focal length Mirror (7) and charge coupling device (8), the lower section of the plane mirror (5) are equipped with sample stage (9) and extinction plate (10) successively, institute Stating sample stage (9) can be three-dimensional mobile relative to extinction plate (10)；The polarizer (4), analyzer (6) and charge coupling device (8) it is electrically connected respectively with computer (11).
- 2. skin neoplasin imaging device according to claim 1, it is characterised in that the extinction plate (10) is equipped with sliding slot (100), upright slide rail (12) is slidably equipped with the sliding slot (100), the sample stage (10) is up and down reciprocatingly slidedly arranged on upright slide rail (12) on.
- 3. skin neoplasin imaging device according to claim 2, it is characterised in that the sliding slot (100) includes a horizontal stroke To sliding slot and a plurality of longitudinal chute to intersect vertically with horizontal concrete chute.
- 4. skin neoplasin imaging device according to claim 1, it is characterised in that the plane mirror (5) is by generally plating The eyeglass that anti-reflection film (50), half have plated Anti-reflective coating (51) is formed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711151719.5A CN108007870A (en) | 2017-11-19 | 2017-11-19 | A kind of skin neoplasin imaging device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711151719.5A CN108007870A (en) | 2017-11-19 | 2017-11-19 | A kind of skin neoplasin imaging device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108007870A true CN108007870A (en) | 2018-05-08 |
Family
ID=62053039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711151719.5A Pending CN108007870A (en) | 2017-11-19 | 2017-11-19 | A kind of skin neoplasin imaging device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108007870A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110327041A (en) * | 2019-06-27 | 2019-10-15 | 天津大学 | A kind of reflective optic EEG signals sensor of sandwich structure |
| CN113058875A (en) * | 2021-04-22 | 2021-07-02 | 慕贝尔汽车部件（太仓）有限公司 | Automatic detection system for workpiece surface flaws |
-
2017
- 2017-11-19 CN CN201711151719.5A patent/CN108007870A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110327041A (en) * | 2019-06-27 | 2019-10-15 | 天津大学 | A kind of reflective optic EEG signals sensor of sandwich structure |
| CN110327041B (en) * | 2019-06-27 | 2021-08-13 | 天津大学 | Reflection type optical brain electrical signal sensor with sandwich structure |
| CN113058875A (en) * | 2021-04-22 | 2021-07-02 | 慕贝尔汽车部件（太仓）有限公司 | Automatic detection system for workpiece surface flaws |
| CN113058875B (en) * | 2021-04-22 | 2022-07-26 | 慕贝尔汽车部件（太仓）有限公司 | Automatic detection system for workpiece surface flaws |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10694982B2 (en) | Imaging apparatus, authentication processing apparatus, imaging method, authentication processing method | |
| US20180289983A1 (en) | Augmented reality glasses to help doctors visualize radiation patterns and overall tumor shape/size | |
| DE4421242B4 (en) | Image capture device for an identification system | |
| CN204258901U (en) | For mobile terminal palm vein identification device and comprise its smart mobile phone | |
| CN108007870A (en) | A kind of skin neoplasin imaging device | |
| CN101030249A (en) | Personal authentication device | |
| CN101627913B (en) | Identity information identification method and identity information identification system | |
| CN1792318A (en) | Apparatus for imaging of ocular tissue | |
| CN104573676B (en) | The iris identification device of the reflective interference of safety goggles | |
| Mehrubeoglu et al. | Real-time eye tracking for password authentication | |
| CN103679878A (en) | Access control system based on finger vein recognition | |
| Jung et al. | Analysis of the number of enlarged pores according to site, age, and sex | |
| US10596392B2 (en) | Dermatology radiotherapy system with hybrid imager | |
| CN207182298U (en) | A kind of three-dimensional finger vein recognition system | |
| Zhou et al. | An automatic multi-view disease detection system via collective deep region-based feature representation | |
| CN205094404U (en) | Fluorescence laser image detector | |
| CN202069572U (en) | Optical imaging equipment applied on skins | |
| CN105279501B (en) | A kind of Zigzag type palm print collecting device of dark background | |
| WO2020191595A1 (en) | Biological feature recognition device and method, and electronic device | |
| Vats et al. | Detecting oral cancer: the potential of artificial intelligence | |
| CN203689592U (en) | Access control system based on finger vein recognition | |
| CN209103321U (en) | A kind of iris capturing equipment and iris authentication system | |
| CN105259155B (en) | A kind of translucent imaging method of fast noninvasive and device | |
| CN209770396U (en) | salivary gland function measuring device for radioactive tumor treatment | |
| CN209172499U (en) | A kind of laser output device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20180508 |