CN107998065A - A kind of skin toxin expelling complexing frost and its production method - Google Patents
A kind of skin toxin expelling complexing frost and its production method Download PDFInfo
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- CN107998065A CN107998065A CN201711454219.9A CN201711454219A CN107998065A CN 107998065 A CN107998065 A CN 107998065A CN 201711454219 A CN201711454219 A CN 201711454219A CN 107998065 A CN107998065 A CN 107998065A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/26—Aluminium; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention discloses a kind of skin toxin expelling complexing frost and its production method, toxin expelling complexing frost is by cetostearyl alcohol/cetearyl glucoside, 100 stearates of tristerin/PEG, vaseline, white oil, caprylic/capric triglyceride, cyclopentasiloxane and/or cyclohexasiloxane, dimethyl silicone polymer, bentonite, methyl esters, propyl ester, glycerine, allantoin, propane diols, hyaluronic acid, xanthan gum, kaolin, metallothionein, ore deposit plant compounds extracting solution, preservative and water are made, wherein, kaolin, bentonite, the mass ratio of metallothionein and ore deposit plant compounding extracting solution is 5:3:2:2；The ore deposit plant compounding extracting solution is by licorice, tea extract, Mel extract and smithsonite extracting solution in mass ratio 2:5:3:3 compositions.The toxin expelling complexing frost of the present invention can make unsound skin obtain obvious reparation and protection, be a resistant to pollution comprehensive care type product comprehensively.
Description
Technical field
The invention belongs to cosmetic field, and in particular to a kind of skin toxin expelling complexing frost and its production method.
Background technology
Instantly, trade effluent and sanitary sewage have the phenomenon of any discharge, cause substantial amounts of pollutant to be released to soil
In.In the cosmetics that consumer uses, also have illegal businessman sale the whitening and freckle-removing product containing heavy metal, and these by
The environment of pollution and threat to human skin health are all the major issues that can not be ignored.Wherein, heavy metal contaminants are not
Physical and mental health is only threaten, and application on human skin is become dim, coarse, it is no longer healthy.Commercially available general cosmetics, can not be effective
It is complexed the heavy metal ion of skin surface, it is impossible to be effectively improved skin problem.
Lead is one of heavy metal contaminants common in environment, its approach polluted includes the skin care item inferior containing heavy metal
And vehicle exhaust, waste incineration, atmospheric sedimentation, industrial wastewater discharge etc..Lead in gasoline additive is considered as busy horse
The main reason for roadside and Lead Pollution in urban.After lead additive is prohibited, waste incineration becomes new pollution sources again.Lead and
Its compound has human body larger toxicity simultaneously can be in people's cylinder accumulation, major determinant nervous system, hematological system and digestive system.
In addition, lead has skin health very big threat, it can make skin dim, coarse.
Though low but its toxicity of compound of cadmium activity is very big, by the air of cadmium pollution and food except harm to the human body is serious,
And skin is damaged.Incubation period of the cadmium in human body is very long, is generally not easy to be noticeable.Cadmium can be through respiratory system or digestion
System invades human body, and long-term exposure can cause anosmia, gum macula lutea or gradually into yellow circle, and cadmium compound is not easy to be inhaled by enteron aisle
Receive, but can lodge in liver through breathing by body absorption or kidney causes damage.In addition, Long Term Contact cadmium and its compound
Skin health conditions can be caused.
In addition, the element such as other heavy metals such as mercury (Hg), silver-colored (Ag), arsenic (As) can also damage skin.
With the influence of the skin care item of the intake of junk food, environmental pollution and abuse poor quality, excessive heavy metal pollution
Thing can seriously damage skin health.Therefore new method is found to improve skin health be researcher's asking of needing urgently to solve
Topic.
The content of the invention
In order to solve environment (including soil, air, with water) instantly neutralize heavy metal ion in cosmetics inferior it is exceeded and
Caused skin inferior health problem, primary and foremost purpose of the invention is to provide a kind of skin toxin expelling complexing frost, to improve skin
Health status.
Another object of the present invention is to provide the production method of above-mentioned skin toxin expelling complexing frost.
The purpose of the present invention is achieved through the following technical solutions：
A kind of skin toxin expelling complexing frost, is made by the component of following mass percent：
Wherein, the mass ratio of kaolin, bentonite, metallothionein and ore deposit plant compounding extracting solution is 5:3:2:2；
The ore deposit plant compounding extracting solution is carried by licorice, tea extract, Mel extract and smithsonite
Take liquid in mass ratio 2:5:3:3 compositions.
In above-mentioned formula, cetostearyl alcohol/cetearyl glucoside, tristerin/PEG-100 stearates
All it is commercially available emulsifying agent.Caprylic/capric triglyceride is a kind of commercially available reagent, can be used as the base-material of moisturizing factor
Stabilizer, antifreezing agent, the homogeneous agent of cosmetics.
Kaolin in the formula has characterization of adsorption to heavy metal ion.Bentonite is using montmorillonite as essential mineral
The nonmetallic minerals of component, there are some cations, such as Cu, Mg, Na, K, these sun for the layer structure that montmorillonite structure cell is formed
The effect of ion and montmorillonite structure cell is very unstable, is easily partially or completely exchanged by other cations, therefore has preferable ion exchangeable.Upper
State in formula, bentonite is used as the adsorbent of lead ion and cadmium ion, its removal rate and adsorbance to heavy metal ion compared with
It is high.
Metallothionein in the formula is the Homocysteine of a kind of low molecule quality, without aromatic amino acid
The non-enzymatic protein of composition and better heat stability, is purchased from Xi'an Bai Chuan bio tech ltd, its metallothionein is to gold
Belonging to ion has compared with high affinity, can combine closely with toxic metals such as lead, arsenic, mercury, solves removing heavy metals toxin, and daily
Clinical optimal biologic detoxication agent.And internal and skin metabolism of trace elements can be participated in, according to micro- situation, release automatically
Metal ion is released, element needed for supplement, regulating microelement balance, strengthens immunocompetence.
In the ore deposit plant compounding extracting solution, the licorice of South Korea's hundred bright morals production, tea extract, honey extraction
Thing is purchased from hundred Hao Bo Co., Ltds of Guangzhou, and the glycyrrhizin that radix glycyrrhizae contains is to harmful heavy metal ions after oxygen radical oxidation
The toxin of generation produces neutralization, metal toxin is lost toxicity and forms sediment, protects skin.Tea polyphenols in tealeaves can
Harmful heavy metal ions precipitation or reduction are complexed, it is lost the metal harmful toxins that oxidation produces, plays detoxication；At the same time
Containing abundant VE in tealeaves, VE has very strong antioxidant action, can prevent or reduce heavy metal ion oxidation and produce toxin, reduction has
Evil heavy metal endangers skin.
In addition, the smithsonite extracting solution in ore deposit plant compounding extracting solution is purchased from good method lion (GATTEFOSSE) company of France.
Smithsonite extracting solution is a kind of zinc carbonate, and Zn-ef ficiency is indispensable trace element during growth in humans's physiology of development, zinc
Very important effect is played in skin.Due to keeping double-spiral structure, it can promote sulfur-containing amino acid (cysteine) to turn
Skin protein is turned to, much researches show that zinc promotes the synthesis of metallothionein, and metallothionein is cellular stress
Albumen, is present in DNA indirect protection mechanism, is their feature with metal ion chelant, and this inducing action can be containing gold
There is the mechanism of action for accelerating toxin expelling and protecting skin in the category sulfoprotein formula.In combination with licorice, tealeaves extraction
The interaction of thing, Mel extract, plays and accelerates the skin that chelant is injured caused by the factors such as Heavy-metal Polluted Environment
Skin has obtained obvious reparation, significant effect.
The preferred PLUS preservatives of the preservative.
The skin toxin expelling complexing frost of the present invention is preferably made by the component of following mass percent：
The production method of skin toxin expelling complexing frost of the present invention comprises the following steps：
(1) by cetostearyl alcohol/cetearyl glucoside, tristerin/PEG-100 stearates, vaseline,
White oil, caprylic/capric triglyceride, cyclopentasiloxane and/or cyclohexasiloxane, dimethyl silicone polymer, bentonite, methyl esters,
Propyl ester mixes, and is heated to 80-85 DEG C, stirs and evenly mixs to obtain A phases and expects；
(2) 80-85 is heated to after mixing water, glycerine, allantoin, propane diols, hyaluronic acid, xanthan gum and kaolin
DEG C, stir and evenly mix, the A phases for adding step (1) are expected, homogeneous to complete emulsification；
(3) material of step (2) is cooled to 60~65 DEG C, stirs evenly；Treat that material is cooled to 40~45 DEG C, add metallothionein
In vain, ore deposit plant compounding extracting solution and preservative, stir evenly, filtering and discharging.
The present invention is had the following advantages relative to the prior art and effect：
Its white main active ingredient of skin toxin expelling complexing of the present invention is that there are kaolin, bentonite, metallothionein
While with the addition of again ore deposit plant compounding extracting solution, be in mass ratio 5:3:2:Best results when 2, have given full play to four collaborations
The effect of synergy.Using the inducing action between metallothionein and smithsonite, reach the effect for accelerating toxin expelling and protecting skin.
Therefore, toxin expelling of the invention complexing frost can obtain injury or unsound skin caused by by factors such as Heavy-metal Polluted Environments
Obvious reparation and protection.It is a resistant to pollution comprehensive care type product comprehensively.
Embodiment
With reference to embodiment, the present invention is described in further detail, but the implementation of the present invention is not limited to this.
Comparative example 1-8
A kind of skin toxin expelling complexing frost, except bentonite, kaolin, metallothionein, the content (quality hundred of other raw materials
Point than) it is as follows：
Cetostearyl alcohol/cetearyl glucoside 2%, tristerin/PEG-100 stearates 1%, vaseline
2%, white oil 5%, caprylic/capric triglyceride 3%, cyclopentasiloxane and/or cyclohexasiloxane 2%, dimethyl silicone polymer
0.5%, methyl esters 0.2%, propyl ester 0.1%, glycerine 5%, allantoin 0.2%, propane diols 4%, hyaluronic acid 0.05%, xanthan gum
0.3%, PLUS preservative (place of production U.S. Ya Shilan, is purchased from Guangzhou Hui Lang bio tech ltd) 0.4%, surplus is water；
Bentonite, kaolin, the content of metallothionein are as shown in table 1：
The content (mass percent) of three kinds of raw materials in table 1, comparative example 1-8
| Comparative example | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
| Kaolin | 5 | 0 | 5 | 0 | 0 | 5 | 5 | 0 |
| Bentonite | 3 | 3 | 0 | 0 | 3 | 0 | 3 | 0 |
| Metallothionein | 2 | 0 | 0 | 2 | 2 | 2 | 0 | 0 |
Test assessment：
(1) trial target：The toxin expelling complexing frost of comparative example 1-8；
(2) tested crowd：60 women of the age between 20-50；
(3) cycle is tried out：30 days：2 times a day (once in the morning and once at night), applying amount is 1g~1.5g, and full face is uniformly applied to
Basic absorption；
(4) health status：Subjects skin's health, no skin allergy history, meets subject and volunteers inclusion criteria；(5) survey
Assessment result is tried as shown in table 2- tables 9：
The feedback conclusive table (number) on probation of table 2,1 product of comparative example
| Assessment item | Very well | Generally | Difference |
| Whitening bright color | 90 | 7 | 3 |
| Skin smooth | 82 | 10 | 8 |
| Security | 100 | 0 | 0 |
The feedback conclusive table (number) on probation of table 3,2 product of comparative example
| Assessment item | Very well | Generally | Difference |
| Whitening bright color | 30 | 15 | 55 |
| Skin smooth | 25 | 30 | 45 |
| Security | 100 | 0 | 0 |
The feedback conclusive table (number) on probation of table 4,3 product of comparative example
| Assessment item | Very well | Generally | Difference |
| Whitening bright color | 30 | 18 | 52 |
| Skin smooth | 22 | 20 | 58 |
| Security | 100 | 0 | 0 |
The feedback conclusive table (number) on probation of table 5,4 product of comparative example
| Assessment item | Very well | Generally | Difference |
| Whitening bright color | 50 | 35 | 15 |
| Skin smooth | 48 | 24 | 28 |
| Security | 100 | 0 | 0 |
The feedback conclusive table (number) on probation of table 6,5 product of comparative example
| Assessment item | Very well | Generally | Difference |
| Whitening bright color | 72 | 20 | 8 |
| Skin smooth | 75 | 13 | 12 |
| Security | 100 | 0 | 0 |
The feedback conclusive table (number) on probation of table 7,6 product of comparative example
| Assessment item | Very well | Generally | Difference |
| Whitening bright color | 75 | 20 | 5 |
| Skin smooth | 80 | 12 | 8 |
| Security | 100 | 0 | 0 |
The feedback conclusive table (number) on probation of table 8,7 product of comparative example
| Assessment item | Very well | Generally | Difference |
| Whitening bright color | 62 | 20 | 18 |
| Skin smooth | 61 | 18 | 21 |
| Security | 100 | 0 | 0 |
The feedback conclusive table (number) on probation of table 9,8 product of comparative example
| Assessment item | Very well | Generally | Difference |
| Whitening bright color | 0 | 2 | 98 |
| Skin smooth | 0 | 1 | 99 |
| Security | 100 | 0 | 0 |
Table 2- tables 9 test result indicates that：When comprising only a kind of in kaolin, bentonite or metallothionein in component
(comparative example 2-4), be not significantly improved skin health the effect of, most people are unsatisfied with product.
When toxin expelling is complexed two kinds of component compoundings in frost formula, positive effect increase (comparative example 5-7), shows that both have association
With the effect of synergy.
And by it was found that, be used alone metallothionein better than be used alone kaolin, bentonite.Compounding use
During metallothionein, effect is compounded also superior to bentonite and kaolin.Show that metallothionein is played to pass in formula indirectly
Important effect.
Comparative example 8 does not add kaolin, bentonite, metallothionein, and skin is not improved.
When the compound proportion of kaolin, bentonite, metallothionein is 5:3:Effect is pretty good (comparative example 1) when 2, but surveys
Test result, which is shown, is still not reaching to optimum efficiency, and consumer wishes that promising result can be reached in 20 days.
Embodiment
In order to meet the market demand, 2% ore deposit plant compounding extracting solution is added in the formula of comparative example 1；Ore deposit plant is answered
Composition with extracting solution is as shown in the table：
| Component | Mass ratio |
| Licorice | 2 |
| Tea extract | 5 |
| Mel extract | 3 |
| Smithsonite extract | 3 |
Comparative example 1 and 20 days using effects of embodiment product are as shown in the table：
As can be seen that the significant effect of embodiment product, meets customer demand, when kaolin, bentonite, metallothionein
The mass ratio with ore deposit plant compounding extracting solution is 5 in vain:3:2:Best results when 2, four have the function that synergy.
Above-described embodiment is the preferable embodiment of the present invention, but embodiments of the present invention and from above-described embodiment
Limitation, other any Spirit Essences without departing from the present invention with made under principle change, modification, replacement, combine, simplification,
Equivalent substitute mode is should be, is included within protection scope of the present invention.
Claims (4)
1. a kind of skin toxin expelling complexing frost, it is characterised in that be made by the component of following mass percent：
Wherein, the mass ratio of kaolin, bentonite, metallothionein and ore deposit plant compounding extracting solution is 5:3:2:2；
The ore deposit plant compounding extracting solution is by licorice, tea extract, Mel extract and smithsonite extracting solution
In mass ratio 2:5:3:3 compositions.
2. skin toxin expelling complexing frost according to claim 1, it is characterised in that be by the component system of following mass percent
：
3. skin toxin expelling complexing frost according to claim 1 or 2, it is characterised in that：The preservative is PLUS anti-corrosions
Agent.
4. a kind of production method of skin toxin expelling complexing frost, it is characterised in that comprise the following steps：
(1) by cetostearyl alcohol/cetearyl glucoside, tristerin/PEG-100 stearates, vaseline, white
Oil, caprylic/capric triglyceride, cyclopentasiloxane and/or cyclohexasiloxane, dimethyl silicone polymer, bentonite, methyl esters, third
Ester mixes, and is heated to 80-85 DEG C, stirs and evenly mixs to obtain A phases and expects；
(2) 80-85 DEG C is heated to after mixing water, glycerine, allantoin, propane diols, hyaluronic acid, xanthan gum and kaolin, is stirred
Mixing is mixed, the A phases for adding step (1) are expected, homogeneous to complete emulsification；
(3) material of step (2) is cooled to 60~65 DEG C, stirs evenly；Treat that material is cooled to 40~45 DEG C, add metallothionein,
Ore deposit plant compounds extracting solution and preservative, stirs evenly, filtering and discharging.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111743823A (en) * | 2020-07-16 | 2020-10-09 | 广州蜜妆生物科技有限公司 | Skin detoxifying essence milk |
| EP3900698A1 (en) | 2020-04-23 | 2021-10-27 | Leibniz-Institut für Polymerforschung Dresden e.V. | Product and process for decontamination of harmful substances from the skin |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103976921A (en) * | 2014-05-31 | 2014-08-13 | 广州丹奇日用化工厂有限公司 | Cavalerie mosla herb extracting solution, as well as preparation method and application thereof |
| CN106580810A (en) * | 2017-02-11 | 2017-04-26 | 佛山文森特知识产权服务有限公司 | Blueberry extract-containing anti-pollution mask |
| CN106821861A (en) * | 2017-03-13 | 2017-06-13 | 南通蛇类治疗研究所 | Ferment zymoprotein toxin-expelling and face nourishing content in freckle cream |
-
2017
- 2017-12-28 CN CN201711454219.9A patent/CN107998065A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103976921A (en) * | 2014-05-31 | 2014-08-13 | 广州丹奇日用化工厂有限公司 | Cavalerie mosla herb extracting solution, as well as preparation method and application thereof |
| CN106580810A (en) * | 2017-02-11 | 2017-04-26 | 佛山文森特知识产权服务有限公司 | Blueberry extract-containing anti-pollution mask |
| CN106821861A (en) * | 2017-03-13 | 2017-06-13 | 南通蛇类治疗研究所 | Ferment zymoprotein toxin-expelling and face nourishing content in freckle cream |
Non-Patent Citations (1)
| Title |
|---|
| 王建新等: "《化妆品植物原料大全》", 30 June 2012, 中国纺织出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3900698A1 (en) | 2020-04-23 | 2021-10-27 | Leibniz-Institut für Polymerforschung Dresden e.V. | Product and process for decontamination of harmful substances from the skin |
| WO2021214209A1 (en) | 2020-04-23 | 2021-10-28 | Leibniz-Institut Für Polymerforschung Dresden E.V. | Product and process for the decontamination of nanoparticles from the skin |
| CN111743823A (en) * | 2020-07-16 | 2020-10-09 | 广州蜜妆生物科技有限公司 | Skin detoxifying essence milk |
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