CN107961257A - A kind of preparation method for wearing yellow antipyretic capsule - Google Patents
A kind of preparation method for wearing yellow antipyretic capsule Download PDFInfo
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- CN107961257A CN107961257A CN201711257807.3A CN201711257807A CN107961257A CN 107961257 A CN107961257 A CN 107961257A CN 201711257807 A CN201711257807 A CN 201711257807A CN 107961257 A CN107961257 A CN 107961257A
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- herba andrographitis
- antipyretic
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- 239000002775 capsule Substances 0.000 title claims abstract description 28
- 230000001754 anti-pyretic effect Effects 0.000 title claims abstract description 23
- 239000002221 antipyretic Substances 0.000 title claims abstract description 23
- 238000002360 preparation method Methods 0.000 title claims abstract description 20
- 239000000843 powder Substances 0.000 claims abstract description 15
- 238000000855 fermentation Methods 0.000 claims abstract description 10
- 230000004151 fermentation Effects 0.000 claims abstract description 10
- 235000000914 Solidago virgaurea Nutrition 0.000 claims abstract description 9
- 239000000463 material Substances 0.000 claims abstract description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 8
- 244000197975 Solidago virgaurea Species 0.000 claims abstract description 7
- 235000020985 whole grains Nutrition 0.000 claims abstract description 7
- 241000186000 Bifidobacterium Species 0.000 claims abstract description 6
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 5
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims abstract description 5
- 229920002261 Corn starch Polymers 0.000 claims abstract description 4
- 239000008120 corn starch Substances 0.000 claims abstract description 4
- 238000004806 packaging method and process Methods 0.000 claims abstract description 4
- 239000006071 cream Substances 0.000 claims description 9
- 238000001035 drying Methods 0.000 claims description 9
- 239000000706 filtrate Substances 0.000 claims description 9
- 238000002156 mixing Methods 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 241000894006 Bacteria Species 0.000 claims description 6
- 108090000790 Enzymes Proteins 0.000 claims description 6
- 102000004190 Enzymes Human genes 0.000 claims description 6
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 6
- 229910001220 stainless steel Inorganic materials 0.000 claims description 6
- 239000010935 stainless steel Substances 0.000 claims description 6
- 238000001914 filtration Methods 0.000 claims description 5
- 241000235342 Saccharomycetes Species 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 230000009849 deactivation Effects 0.000 claims description 3
- 235000019359 magnesium stearate Nutrition 0.000 claims description 3
- 230000009471 action Effects 0.000 claims description 2
- 239000000835 fiber Substances 0.000 claims description 2
- 238000000643 oven drying Methods 0.000 claims description 2
- 210000000481 breast Anatomy 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 5
- 238000000034 method Methods 0.000 abstract description 5
- 238000000605 extraction Methods 0.000 abstract description 4
- 108010059892 Cellulase Proteins 0.000 abstract description 3
- 229940106157 cellulase Drugs 0.000 abstract description 3
- 231100000419 toxicity Toxicity 0.000 abstract description 3
- 230000001988 toxicity Effects 0.000 abstract description 3
- 230000015556 catabolic process Effects 0.000 abstract description 2
- 238000006731 degradation reaction Methods 0.000 abstract description 2
- 238000005469 granulation Methods 0.000 abstract description 2
- 230000003179 granulation Effects 0.000 abstract description 2
- 238000001556 precipitation Methods 0.000 abstract description 2
- 239000006041 probiotic Substances 0.000 abstract description 2
- 235000018291 probiotics Nutrition 0.000 abstract description 2
- 229940099112 cornstarch Drugs 0.000 abstract 1
- 238000011049 filling Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 6
- 229940079593 drug Drugs 0.000 description 4
- 229940088598 enzyme Drugs 0.000 description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 4
- 240000004183 Bongardia chrysogonum Species 0.000 description 2
- 244000025254 Cannabis sativa Species 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 235000010980 cellulose Nutrition 0.000 description 2
- 235000014655 lactic acid Nutrition 0.000 description 2
- 239000004310 lactic acid Substances 0.000 description 2
- 230000036407 pain Effects 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 1
- 241000221079 Euphorbia <genus> Species 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 206010046306 Upper respiratory tract infection Diseases 0.000 description 1
- 235000009499 Vanilla fragrans Nutrition 0.000 description 1
- 244000263375 Vanilla tahitensis Species 0.000 description 1
- 235000012036 Vanilla tahitensis Nutrition 0.000 description 1
- 241001123263 Zostera Species 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 206010001093 acute tonsillitis Diseases 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000002579 anti-swelling effect Effects 0.000 description 1
- 239000010231 banlangen Substances 0.000 description 1
- 235000013405 beer Nutrition 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 208000020029 respiratory tract infectious disease Diseases 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a kind of preparation method for wearing yellow antipyretic capsule, the active ingredient of goldenrod, Herba Andrographitis is extracted to obtain thick paste with the technique being combined of alcohol precipitation processing by decocting, cellulase degradation extraction, and fermentation process is carried out to Herba Andrographitis fecula with probiotics saccharomyces cerevisiae, Bifidobacterium and obtains fermentation Herba Andrographitis powder, obtain wearing yellow antipyretic capsule after granulation, whole grain, filling capsule, packaging after fermentation Herba Andrographitis powder, cornstarch and thick paste are mixed evenly.The preparation method of the present invention improves the utilization rate of medicinal material active ingredient, and preparation wears yellow antipyretic capsule and can reduce toxicity and utilizations that be preferably absorbed by the body, improvement curative effect.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, more particularly to a kind of preparation method for wearing yellow antipyretic capsule.
Background technology
Wearing yellow antipyretic capsule can be clearing heat and detoxicating, be one kind be mainly used for acute upper respiratory infection, acute tonsillitis,
The medicine of pharyngitis, its main component are Herba Andrographitis and goldenrod.Herba Andrographitis also known as Chun Lianqiuliu, Banlangen, Euphorbia, gall bladder
Grass, golden vanilla, golden tack, India's grass, eel grass etc., are annual herb plants, there is clearing heat and detoxicating, anti-inflammatory, swelling and pain relieving effect.
Goldenrod nature and flavor are pungent, bitter, tepor, can dispelling wind removing toxic substances, promoting circulation of blood of bringing down a fever, swelling and pain relieving.At present, the preparation side of yellow antipyretic capsule is worn
Method is mainly the crude drug powder and Herba Andrographitis, the extraction concentrated extract mixing granulation of goldenrod after Herba Andrographitis is crushed, and is then filled out
Capsule is filled to be made.This method is very low to the utilization rate of active ingredient in crude drug powder, and absorption of the human body to effective ingredient has
Limit, so as to limit the effect of wearing yellow antipyretic capsule.Therefore, it is necessary to existing preparation method is made improvements.
The content of the invention
A kind of the defects of the object of the invention is exactly to make up prior art, there is provided preparation method for wearing yellow antipyretic capsule.
The present invention is achieved by the following technical solutions：
A kind of preparation method for wearing yellow antipyretic capsule, comprises the following steps：
（1）180-200 parts by weight goldenrod, 80-100 parts by weight Herba Andrographitis are fitted into multi-function extractor, added suitable
2-4h is decocted in 10-15 times of water of medicinal material gross weight, filtering, add 2-2.5 percent by weight fiber into filter residue again after collecting filtrate
Plain enzyme and water of 8-10 times equivalent to medicinal material gross weight the enzymolysis processing 2-4h under the conditions of 40-50 DEG C, pH5-6,85-95 DEG C of enzyme deactivation
Filtered after 3-5min, collect filtrate, the filtrate obtained twice is merged, is concentrated under reduced pressure into clear cream；
（2）By step（1）Obtained clear cream is squeezed into Alcohol-settling tank, is added the ethanol stirring 0.5-1h of 90-95%, is then stood 48-
72h, thick paste is concentrated under reduced pressure into after filtering by filter vacuum；
（3）By 30-40 parts by weight Herba Andrographitis powder and 0.5-1 parts by weight saccharomyces cerevisiae, 0.1-0.15 parts by weight Bifidobacterium and
PH is adjusted to 3-4 after the mixing of 10-15 parts by weight water, ferment 24-48h in 35-45 DEG C, then in 60-80 DEG C of drying, is ground to
100-200 mesh, obtains fermentation Herba Andrographitis powder；
（4）By step（3）Obtained fermentation Herba Andrographitis powder and 1-1.5 parts by weight Corn starch is added in trough type mixing machine and stirred
10-15min, then adds step（2）Obtained thick paste is stirred for 10-15min, is pelletized and incited somebody to action with 14-16 mesh stainless steel mesh
The wet granular that makes is sent into heated-air circulation oven drying, then with 40-60 mesh stainless steel mesh whole grains, the dry particl after whole grain is added
Enter 0.6-0.8 parts by weight magnesium stearate mixing 0.5-1h, fill capsule, obtain wearing yellow antipyretic capsule after packaging.
The step（1）In the temperature that is concentrated under reduced pressure be 60-85 DEG C.
The step（1）The 1.14-1.16 when relative density of middle clear cream is 85 DEG C.
The step（2）The temperature of middle vacuum-concentrcted is 60-80 DEG C.
The step（2）1.31-1.35 when middle thick paste relative density is 60-80 DEG C.
The saccharomycete, the living bacteria count amount of lactic acid bacteria are hundred million CFU/g of 10-20.
The step（4）Middle drying temperature is 65-75 DEG C, drying time 3-4h.
It is an advantage of the invention that：
One aspect of the present invention by decocting, cellulase degradation extraction with alcohol precipitation handle the technique being combined to goldenrod,
The active ingredient of Herba Andrographitis is extracted to obtain extracting solution thick paste, according to containing a large amount of celluloses in goldenrod, Herba Andrographitis medicinal material,
The characteristics of hindering active ingredient to be fully dissolved out, is handled it using cellulase, so as to improve the extraction of active ingredient
Rate, improves active constituent content in thick paste；On the one hand using probiotics saccharomyces cerevisiae, Bifidobacterium to Herba Andrographitis fecula into
Row fermentation process, had not only reduced the toxicity of Herba Andrographitis crude drug powder, but also added the dissolution of active ingredient in crude drug powder, while beer
Saccharomycete and Bifidobacterium can also aid in absorption of the intestines and stomach to medicine, so as to play the effect of more preferable.The preparation side of the present invention
Method improves the utilization rate of medicinal material active ingredient, and preparation wears yellow antipyretic capsule and can reduce toxicity and preferably by human body
Absorb, improve curative effect.
Embodiment
A kind of preparation method for wearing yellow antipyretic capsule, comprises the following steps：
（1）180 parts by weight goldenrods, 80 parts by weight Herba Andrographitis are fitted into multi-function extractor, are added total equivalent to medicinal material
The water that 10 times of weight decocts 2h, and filtering, collect and add 2 part by weight of cellulose enzymes and total equivalent to medicinal material after filtrate into filter residue again
The water that 8 times of weight filters after 40 DEG C, enzymolysis processing 2h under the conditions of pH5,85 DEG C enzyme deactivation 3min, collects filtrate, will obtain twice
Filtrate merge, be concentrated under reduced pressure into clear cream；
（2）By step（1）Obtained clear cream is squeezed into Alcohol-settling tank, is added 90% ethanol stirring 0.5h, is then stood 48h, filter
Filter vacuum is concentrated under reduced pressure into thick paste afterwards；
（3）By 30 parts by weight Herba Andrographitis powder and 0.5 parts by weight saccharomyces cerevisiae, 0.1 parts by weight Bifidobacterium and 10 parts by weight water
PH is adjusted to 3 after mixing, ferment 24h in 35 DEG C, then in 60 DEG C of drying, is ground to 100 mesh, obtains fermentation Herba Andrographitis powder；
（4）By step（3）Obtained fermentation Herba Andrographitis powder and 1 parts by weight Corn starch, which are added in trough type mixing machine, stirs 10min,
Then step is added（2）Obtained thick paste is stirred for 10min, is pelletized with 14 mesh stainless steel mesh and is sent into the wet granular made
Heated-air circulation oven is dried, then with 40 mesh stainless steel mesh whole grains, the dry particl after whole grain is added 0.6 parts by weight magnesium stearate
0.5h is mixed, capsule is filled, obtains wearing yellow antipyretic capsule after packaging.
The step（1）In the temperature that is concentrated under reduced pressure be 60 DEG C.
The step（1）1.14 when the relative density of middle clear cream is 85 DEG C.
The step（2）The temperature of middle vacuum-concentrcted is 60 DEG C.
The step（2）1.31 when middle thick paste relative density is 60 DEG C.
The saccharomycete, the living bacteria count amount of lactic acid bacteria are 1,000,000,000 CFU/g.
The step（4）Middle drying temperature is 65 DEG C, drying time 3h.
Claims (7)
1. a kind of preparation method for wearing yellow antipyretic capsule, it is characterised in that comprise the following steps：
（1）180-200 parts by weight goldenrod, 80-100 parts by weight Herba Andrographitis are fitted into multi-function extractor, added suitable
2-4h is decocted in 10-15 times of water of medicinal material gross weight, filtering, add 2-2.5 percent by weight fiber into filter residue again after collecting filtrate
Plain enzyme and water of 8-10 times equivalent to medicinal material gross weight the enzymolysis processing 2-4h under the conditions of 40-50 DEG C, pH5-6,85-95 DEG C of enzyme deactivation
Filtered after 3-5min, collect filtrate, the filtrate obtained twice is merged, is concentrated under reduced pressure into clear cream；
（2）By step（1）Obtained clear cream is squeezed into Alcohol-settling tank, is added the ethanol stirring 0.5-1h of 90-95%, is then stood 48-
72h, thick paste is concentrated under reduced pressure into after filtering by filter vacuum；
（3）By 30-40 parts by weight Herba Andrographitis powder and 0.5-1 parts by weight saccharomyces cerevisiae, 0.1-0.15 parts by weight Bifidobacterium and
PH is adjusted to 3-4 after the mixing of 10-15 parts by weight water, ferment 24-48h in 35-45 DEG C, then in 60-80 DEG C of drying, is ground to
100-200 mesh, obtains fermentation Herba Andrographitis powder；
（4）By step（3）Obtained fermentation Herba Andrographitis powder and 1-1.5 parts by weight Corn starch is added in trough type mixing machine and stirred
10-15min, then adds step（2）Obtained thick paste is stirred for 10-15min, is pelletized and incited somebody to action with 14-16 mesh stainless steel mesh
The wet granular that makes is sent into heated-air circulation oven drying, then with 40-60 mesh stainless steel mesh whole grains, the dry particl after whole grain is added
Enter 0.6-0.8 parts by weight magnesium stearate mixing 0.5-1h, fill capsule, obtain wearing yellow antipyretic capsule after packaging.
A kind of 2. preparation method for wearing yellow antipyretic capsule according to claim 1, it is characterised in that the step（1）In
The temperature being concentrated under reduced pressure is 60-85 DEG C.
A kind of 3. preparation method for wearing yellow antipyretic capsule according to claim 1, it is characterised in that the step（1）In
The 1.14-1.16 when relative density of clear cream is 85 DEG C.
A kind of 4. preparation method for wearing yellow antipyretic capsule according to claim 1, it is characterised in that the step（2）In
The temperature of vacuum-concentrcted is 60-80 DEG C.
A kind of 5. preparation method for wearing yellow antipyretic capsule according to claim 1, it is characterised in that the step（2）In
1.31-1.35 when thick paste relative density is 60-80 DEG C.
6. a kind of preparation method for wearing yellow antipyretic capsule according to claim 1, it is characterised in that the saccharomycete, breast
The living bacteria count amount of sour bacterium is hundred million CFU/g of 10-20.
A kind of 7. preparation method for wearing yellow antipyretic capsule according to claim 1, it is characterised in that the step（4）In
Drying temperature is 65-75 DEG C, drying time 3-4h.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711257807.3A CN107961257A (en) | 2017-12-04 | 2017-12-04 | A kind of preparation method for wearing yellow antipyretic capsule |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711257807.3A CN107961257A (en) | 2017-12-04 | 2017-12-04 | A kind of preparation method for wearing yellow antipyretic capsule |
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| Publication Number | Publication Date |
|---|---|
| CN107961257A true CN107961257A (en) | 2018-04-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711257807.3A Pending CN107961257A (en) | 2017-12-04 | 2017-12-04 | A kind of preparation method for wearing yellow antipyretic capsule |
Country Status (1)
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1660189A (en) * | 2004-12-31 | 2005-08-31 | 王红莲 | Capsule of Chinese traditional medicine for clearing away heat and toxic materia and preparation method |
| CN1679675A (en) * | 2005-01-28 | 2005-10-12 | 北京正大绿洲医药科技有限公司 | Chuanhuang anti-inflammation drops for clearing away heat and detoxicating, and preparation thereof |
-
2017
- 2017-12-04 CN CN201711257807.3A patent/CN107961257A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1660189A (en) * | 2004-12-31 | 2005-08-31 | 王红莲 | Capsule of Chinese traditional medicine for clearing away heat and toxic materia and preparation method |
| CN1679675A (en) * | 2005-01-28 | 2005-10-12 | 北京正大绿洲医药科技有限公司 | Chuanhuang anti-inflammation drops for clearing away heat and detoxicating, and preparation thereof |
Non-Patent Citations (3)
| Title |
|---|
| 杨吉霞等: "纤维素酶在中药成分提取中的应用", 《中药材》 * |
| 许明淑等: "酶法强化中药提取的研究进展", 《中国中医药信息杂志》 * |
| 谢莉敏等: "益生菌及其在药学研究中的应用", 《药学研究》 * |
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