CN107929918B - Balloon dilation catheter - Google Patents

Balloon dilation catheter Download PDF

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Publication number
CN107929918B
CN107929918B CN201711250210.6A CN201711250210A CN107929918B CN 107929918 B CN107929918 B CN 107929918B CN 201711250210 A CN201711250210 A CN 201711250210A CN 107929918 B CN107929918 B CN 107929918B
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China
Prior art keywords
balloon
state
binding layer
tube
inner tube
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CN201711250210.6A
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Chinese (zh)
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CN107929918A (en
Inventor
田轩
刘建龙
贾伟
田伟
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Beijing Jishuitan Hospital
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Beijing Jishuitan Hospital
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/104Balloon catheters used for angioplasty
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • A61M25/0026Multi-lumen catheters with stationary elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M25/0045Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1002Balloon catheters characterised by balloon shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M29/00Dilators with or without means for introducing media, e.g. remedies
    • A61M29/02Dilators made of swellable material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M2025/0008Catheters; Hollow probes having visible markings on its surface, i.e. visible to the naked eye, for any purpose, e.g. insertion depth markers, rotational markers or identification of type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M25/1002Balloon catheters characterised by balloon shape
    • A61M2025/1004Balloons with folds, e.g. folded or multifolded
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1079Balloon catheters with special features or adapted for special applications having radio-opaque markers in the region of the balloon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1086Balloon catheters with special features or adapted for special applications having a special balloon surface topography, e.g. pores, protuberances, spikes or grooves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
    • A61M2025/1043Balloon catheters with special features or adapted for special applications
    • A61M2025/1088Balloon catheters with special features or adapted for special applications having special surface characteristics depending on material properties or added substances, e.g. for reducing friction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0238General characteristics of the apparatus characterised by a particular materials the material being a coating or protective layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/12Blood circulatory system

Abstract

The utility model provides a sacculus inflation catheter, inflation catheter include the outer tube, the part is located the inner tube in the outer tube, the distal end part of inner tube is followed the distal end of outer tube stretches out, inflation catheter still include collapsible into the multi-valve sacculus, cladding be in the outside constraint layer of using elastic material to make of sacculus, the distal end of sacculus with the distal end of constraint layer with the outer wall sealing connection of inner tube, the proximal end of sacculus with the proximal end of constraint layer with the outer wall sealing connection of outer tube. After the binding layer is arranged, the saccule can still shrink to the state of the original small size after being expanded for many times, so that the product can repeatedly enter a new lesion for expansion, the cost of the product is saved, the operation of doctors is also facilitated, and the saccule can be easily retracted into the sheath tube for taking out after the expansion is finished.

Description

Balloon dilation catheter
Technical Field
The present application relates to balloon dilation catheters, and more particularly to balloon dilation catheters that can be reused multiple times.
Background
Currently, balloon catheters originate in the 60 s of the 20 th century. In 1963, dotter was successful in performing abdominal aortic angiography through stenosed iliac arteries with inadvertent distal arterial catheterization, suggesting that this approach could be used to guide the catheter using a flexible guidewire to directly and gradually dilate stenosed arteries. PTA was successfully performed on patients with severe arterial stenosis of the lower extremities by the first application of coaxial catheters (coaxial catheters) by Dotter et al in 1964. A bare metal stent phase, a drug eluting stent phase, and an emerging fully degradable stent phase then occur. Although the stent has been initially substituted for pure PTA balloon expansion, a PTA balloon catheter must be used for pre-expansion before stent implantation, and thus PTA balloon catheter pre-expansion is an essential treatment tool for stent implantation.
The existing PTA product mainly comprises the structure as shown in fig. 1: the balloon 1 can form three or more petals by the flaps, which are shown in fig. 2 and 3, so that the size of product insertion can be reduced to a great extent, and the balloon can conveniently pass through a narrow lesion position. After the product enters the blood vessel to pass through the lesion position, the saccule is inflated and expanded, and then the pressure is relieved and withdrawn, or the product is placed at other lesion positions to continue to expand.
After the balloon is expanded and depressurized, the product is difficult to recover to the original shape and size, and often, two flat petals are formed, so that the shape of the balloon is much larger than the size of the original petals, the difficulty of recovering the product into a sheath tube is increased, the difficulty of passing through lesion positions when the product is used for expanding other lesions is also increased, and the repeated expansion capacity of one product to more lesions is lost. For multiple lesions or longer lesions it may be necessary to increase the amount of consumable product, increasing the economic burden on the patient.
Content of the application
In order to solve the technical problems, the purpose of the application is to provide a balloon dilation catheter capable of being reused repeatedly.
The utility model provides a sacculus inflation catheter, inflation catheter include the outer tube, the part is located the inner tube in the outer tube, the distal end part of inner tube is followed the distal end of outer tube stretches out, inflation catheter still include collapsible into the multi-valve sacculus, cladding be in the outside constraint layer of using elastic material to make of sacculus, the distal end of sacculus with the distal end of constraint layer with the outer wall sealing connection of inner tube, the proximal end of sacculus with the proximal end of constraint layer with the outer wall sealing connection of outer tube.
Preferably, the balloon dilation catheter has a contracted state and a filled state, and when the balloon dilation catheter is in the contracted state, the balloon is folded into a multi-flap state, and the binding layer is coated outside the balloon and is in the contracted state; when the balloon dilation catheter is in a full state, the balloon is in an inflated state, and the binding layer is expanded to an inflated state by the balloon.
Preferably, at least one developing ring is further arranged on the inner tube.
Preferably, the balloon dilator further comprises a stress diffusion tube arranged at the proximal end of the outer tube and a Y-shaped catheter seat connected with the proximal end of the stress diffusion tube.
Preferably, an inflation channel for inflating the balloon is formed between the inner tube and the outer tube, an inflation port for inflating the balloon is formed at the distal end of the outer tube, and the Y-shaped catheter seat comprises a first catheter communicated with the inner tube and a second catheter communicated with the inflation channel.
Preferably, the hardness of the binding layer is made of silica gel or latex or polyurethane materials, preferably, the binding layer is made of TPU materials, and TPU (Thermoplastic polyurethanes) is named as thermoplastic polyurethane elastomer rubber.
Preferably, the hardness of the binding layer is 20a to 50a.
Preferably, the balloon and the outer tube are made of polyamide materials, and the inner tube is made of single-layer polyamide materials or multi-layer composite materials.
By means of the scheme, the application has the following advantages:
compared with the prior art, the balloon dilation catheter has the advantages that the binding layer is arranged outside the balloon, when the balloon is in the multi-valve folding state, the binding layer is coated outside the balloon and is in the shrinkage state, after the balloon is inflated, the balloon is gradually expanded from the multi-valve folding state, in the process, the multi-valve of the balloon is twisted, and the binding layer is driven to twist in the twisting process due to the high elasticity of the binding layer; when the balloon is contracted from the expansion state, the binding layer is reversely twisted to generate a reverse rotation force and a restoring force to the balloon, so that the balloon is driven to shrink and fold to form multiple petals, and the balloon can almost completely recover to the original folding state.
Only under the anti-rotation force and the restoring force of the binding layer, the flap balloon with a certain memory function can be restored to a folded state, the three wings or the multiple wings are restored by the rotation force, and the balloon is restored to a tightly attached state by the contraction force.
After the binding layer is arranged, the saccule can still shrink to the state of the original small size after being expanded for many times, so that the product can repeatedly enter a new lesion for expansion, the cost of the product is saved, the operation of doctors is also facilitated, and the saccule can be easily retracted into the sheath tube for taking out after the expansion is finished.
The foregoing description is only an overview of the technical solutions of the present application, and in order to make the technical means of the present application more clearly understood, it can be implemented according to the content of the specification, and the following detailed description of the preferred embodiments of the present application will be given with reference to the accompanying drawings.
Drawings
FIG. 1 is a schematic view of a balloon dilation catheter of the prior art;
FIG. 2 is a schematic cross-sectional view of a balloon dilation catheter of the prior art in a contracted state;
FIG. 3 is a schematic view of a balloon dilation catheter of the prior art in a contracted state;
FIG. 4 is a schematic structural view of a balloon dilation catheter described herein;
FIG. 5 is a schematic view of a balloon dilation catheter of the present application in a inflated state;
FIG. 6 is a schematic cross-sectional view of a balloon dilation catheter of the present application in a collapsed state;
FIG. 7 is a schematic view of a balloon dilation catheter of the present application in a collapsed state;
FIG. 8 is a schematic view of the constrained layer of the balloon dilation catheter of the present application in a constrained state during inflation;
FIG. 9 is a schematic view of the constrained layer of the balloon dilation catheter of the present application in a contracted state;
FIG. 10 is a schematic structural view of a balloon dilator according to an embodiment of the present application;
FIG. 11 is a schematic structural view of a balloon dilator according to a second embodiment of the present application;
figure 12 is a schematic structural view of a balloon dilator according to a second embodiment of the present application,
wherein: 1', a balloon; 3', a developing ring; 4', an inner tube; 5', an outer tube; 6', stress diffusion tube; 7', a catheter holder; 1. a balloon; 2. a tie layer; 3. a developing ring; 4. an inner tube; 5. an outer tube; 6. a stress diffusion tube; 7. a catheter hub.
Detailed Description
The detailed description of the present application is further described in detail below with reference to the drawings and examples. The following examples are illustrative of the present application, but are not intended to limit the scope of the present application.
As shown in fig. 4, the balloon dilation catheter of the present application comprises an outer tube, an inner tube partially positioned in the outer tube, and a distal end portion of the inner tube extending from the distal end of the outer tube, and further comprises a balloon which can be folded into multiple petals, a binding layer coated outside the balloon and made of elastic materials, wherein the distal end of the balloon and the distal end of the binding layer are in sealing connection with the outer wall of the inner tube, and the proximal end of the balloon and the proximal end of the binding layer are in sealing connection with the outer wall of the outer tube. And at least one developing ring is arranged on the inner tube. The balloon dilator also comprises a stress diffusion tube arranged at the proximal end of the outer tube and a Y-shaped catheter seat connected with the proximal end of the stress diffusion tube. An inflation channel for inflating the balloon is formed between the inner tube and the outer tube, an inflation port for inflating the balloon is formed at the distal end of the outer tube, and the Y-shaped catheter seat comprises a first catheter communicated with the inner tube and a second catheter communicated with the inflation channel. The hardness of the binding layer is made of silica gel or latex or polyurethane materials, preferably the binding layer is made of TPU materials, and TPU (Thermoplastic polyurethanes) is named as thermoplastic polyurethane elastomer rubber. The hardness of the binding layer is 20a-50 a. The balloon and the outer tube are made of polyamide materials, and the inner tube is made of single-layer polyamide materials or multi-layer composite materials.
As shown in FIG. 5, the balloon dilation catheter is in an inflated state, the balloon is in an inflated state, and the constraining layer is expanded by the balloon to an inflated state.
As shown in fig. 6 and 7, the balloon dilation catheter is in a contracted state, the balloon is folded into multiple petals, and the binding layer is coated outside the balloon and is in a contracted state.
As shown in fig. 8, the schematic diagram of the stress state of the constraining layer in the inflation process of the balloon dilation catheter in the application is shown, the arrow direction is the stress direction of the constraining layer, after the balloon is inflated, the balloon is gradually inflated from the multi-valve folding state, in the process, the multi-valve of the balloon is twisted, and the constraining layer is driven to twist in the twisting process due to the high elasticity of the constraining layer.
As shown in fig. 9, the balloon dilation catheter is shown in a schematic view of the stress state of the constraining layer in the contraction process, the arrow direction is the stress direction of the constraining layer, when the balloon is contracted from the expansion state, the constraining layer is reversely twisted to generate a reverse rotation force and a restoring force on the balloon, and the balloon is driven to contract while being folded to form multiple petals, so that the balloon can almost completely recover to the original folded state. Only under the anti-rotation force and the restoring force of the binding layer, the flap balloon with a certain memory function can be restored to a folded state, the three wings or the multiple wings are restored by the rotation force, and the balloon is restored to a tightly attached state by the contraction force.
In the first embodiment, the balloon dilation catheter is manufactured by performing three-wing folding on the balloon of 4.0×40 PTA balloon catheter, and then cutting a tie tube with an inner diameter of 1.1mm and a wall thickness of 0.15mm to a length of 65 mm. The material of the binding tube is TPU material, and the hardness is 40a. The cut tie-down tube is sleeved on the balloon with good flap so that the balloon is positioned at the middle position of the tie-down tube. Dripping glue into gaps between the constraint tube at the far end of the saccule and the inner tube as well as between the constraint tube and the saccule pin, and bonding and sealing the constraint tube and the inner tube and the saccule pin; and (3) dripping glue water to the seam of the constraint tube at the near end of the saccule, the saccule pin and the outer tube for bonding and sealing. The completed balloon dilation catheter is shown in fig. 10.
In the second embodiment, the balloon dilation catheter is manufactured by folding the PTA balloon with 5.0X100 wings, then tightly wrapping the balloon with a high-elasticity silica gel film with a width of 65mm, a thickness of 0.05mm and a hardness of 30a along one direction for 1-2 circles, as shown in FIGS. 11 and 12, and then bonding the balloon with glue in the axial direction to form a tubular shape. And then, connecting and sealing the two ends of the film with the balloon pin, the inner tube and the outer tube respectively to form a sealed wrapping film.
The invention mainly protects the structure of the binding layer wrapped outside the balloon and the material characteristics of the binding layer. The constraining layer must be soft (hardness between 20a-50 a) and highly elastic (e.g., silicone, latex, polyurethane, etc.) and not have too thick a wall thickness that would otherwise affect the outer diameter and passability of the balloon after folding. If the material is too stiff or the wall thickness is too thick, balloon inflation pressure may be amplified, or the balloon may not fully inflate, or tearing of the constraining layer may result. The balloon dilation catheter material selection, the effect that the skilled person will realize according to this application can select the use, can realize this application will realize the effect can.
In the prior art, the balloon dilation catheter has no structure of a binding layer, the memory of the balloon is poor once the balloon is dilated, the balloon is difficult to recover to the folded state of three wings or multiple wings, even the state of three wings or multiple wings can be recovered, the balloon cannot be recovered to the tightly attached state, the outline size of the balloon is larger even in the state of pressure relief shrinkage, the balloon is difficult to pass through to enter a new stenotic lesion again for dilation, the balloon is larger in size during recovery, larger resistance is generated during recovery in a sheath tube, and particularly, the longer balloon is more difficult to recover into the sheath. After the binding layer is arranged, the saccule can still shrink to the state of the original small size after being expanded for many times, so that the product can repeatedly enter a new lesion for expansion, the cost of the product is saved, the operation of doctors is also facilitated, and the saccule can be easily retracted into the sheath tube for taking out after the expansion is finished.
The foregoing is merely a preferred embodiment of the present application and is not intended to limit the present application, and it should be noted that it will be apparent to those skilled in the art that modifications and variations can be made without departing from the technical principles of the present application, and these modifications and variations should also be regarded as the scope of the present application.

Claims (6)

1. A balloon dilation catheter, characterized by:
the expansion catheter comprises an outer tube, an inner tube, a balloon and a binding layer, wherein the inner tube is partially positioned in the outer tube, the distal end part of the inner tube extends out of the distal end of the outer tube, the expansion catheter further comprises the balloon which can be folded into multiple petals, the binding layer is coated outside the balloon and made of elastic materials, the distal end of the balloon and the distal end of the binding layer are in sealing connection with the outer wall of the inner tube, and the proximal end of the balloon and the proximal end of the binding layer are in sealing connection with the outer wall of the outer tube; the hardness of the binding layer is made of silica gel or latex or polyurethane materials; the hardness of the binding layer is 20a-50 a; when the balloon is inflated, the balloon is gradually inflated from a multi-valve folding state, in the process, the multi-valve of the balloon is twisted, the multi-valve drives the binding layer to twist in the twisting process, and the binding layer is propped up by the balloon to an inflated state; when the balloon is contracted from the expansion state, the binding layer is reversely twisted, and a reverse rotation force and a restoring force are generated on the balloon, so that the balloon is driven to contract and fold to form multiple petals, and the contraction force enables the balloon to return to a tightly attached state.
2. A balloon dilation catheter according to claim 1 wherein:
the balloon dilation catheter has a contracted state and a filling state, when the balloon dilation catheter is in the contracted state, the balloon is folded into a multi-valve state, and the binding layer is coated outside the balloon and is in the contracted state; when the balloon dilation catheter is in a full state, the balloon is in an inflated state, and the binding layer is expanded to an inflated state by the balloon.
3. A balloon dilation catheter according to claim 1 wherein:
and at least one developing ring is arranged on the inner tube.
4. A balloon dilation catheter according to claim 1 wherein:
the balloon dilator also comprises a stress diffusion tube arranged at the proximal end of the outer tube and a Y-shaped catheter seat connected with the proximal end of the stress diffusion tube.
5. A balloon dilation catheter according to claim 4 wherein:
an inflation channel for inflating the balloon is formed between the inner tube and the outer tube, an inflation port for inflating the balloon is formed at the distal end of the outer tube, and the Y-shaped catheter seat comprises a first catheter communicated with the inner tube and a second catheter communicated with the inflation channel.
6. A balloon dilation catheter according to claim 1 wherein:
the balloon and the outer tube are made of polyamide materials, and the inner tube is made of single-layer polyamide materials or multi-layer composite materials.
CN201711250210.6A 2017-11-21 2017-12-01 Balloon dilation catheter Active CN107929918B (en)

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CN2017111662682 2017-11-21
CN201711166268 2017-11-21

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CN107929918B true CN107929918B (en) 2023-06-16

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CN110025874B (en) * 2019-04-24 2020-01-07 广州启骏生物科技有限公司 Balloon dilatation catheter
CN110420375B (en) * 2019-06-27 2022-09-02 先健科技(深圳)有限公司 Balloon catheter and manufacturing method thereof
CN111420248A (en) * 2020-04-09 2020-07-17 玮铭医疗器械(上海)有限公司 Elastic balloon recovery device
CN112642044B (en) * 2021-01-07 2023-08-25 上海翰凌医疗器械有限公司 Dilating tube and vascular sheath
CN114209961A (en) * 2021-11-25 2022-03-22 浙江巴泰医疗科技有限公司 Medicinal balloon dilatation catheter and preparation method thereof
CN116672164B (en) * 2022-02-23 2024-04-19 柏为(武汉)医疗科技股份有限公司 Eustachian tube bracket
CN114534071B (en) * 2022-04-21 2022-08-02 广州启骏生物科技有限公司 Balloon dilatation catheter device

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