CN107911139A - The wireless telecommunication system and method for a kind of implantable medical devices - Google Patents
The wireless telecommunication system and method for a kind of implantable medical devices Download PDFInfo
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- CN107911139A CN107911139A CN201711046064.5A CN201711046064A CN107911139A CN 107911139 A CN107911139 A CN 107911139A CN 201711046064 A CN201711046064 A CN 201711046064A CN 107911139 A CN107911139 A CN 107911139A
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- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04B—TRANSMISSION
- H04B1/00—Details of transmission systems, not covered by a single one of groups H04B3/00 - H04B13/00; Details of transmission systems not characterised by the medium used for transmission
- H04B1/38—Transceivers, i.e. devices in which transmitter and receiver form a structural unit and in which at least one part is used for functions of transmitting and receiving
- H04B1/40—Circuits
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37217—Means for communicating with stimulators characterised by the communication link, e.g. acoustic or tactile
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- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04W—WIRELESS COMMUNICATION NETWORKS
- H04W52/00—Power management, e.g. TPC [Transmission Power Control], power saving or power classes
- H04W52/02—Power saving arrangements
- H04W52/0209—Power saving arrangements in terminal devices
- H04W52/0261—Power saving arrangements in terminal devices managing power supply demand, e.g. depending on battery level
- H04W52/0274—Power saving arrangements in terminal devices managing power supply demand, e.g. depending on battery level by switching on or off the equipment or parts thereof
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02D—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN INFORMATION AND COMMUNICATION TECHNOLOGIES [ICT], I.E. INFORMATION AND COMMUNICATION TECHNOLOGIES AIMING AT THE REDUCTION OF THEIR OWN ENERGY USE
- Y02D30/00—Reducing energy consumption in communication networks
- Y02D30/70—Reducing energy consumption in communication networks in wireless communication networks
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- Mobile Radio Communication Systems (AREA)
- Electrotherapy Devices (AREA)
Abstract
The present invention provides a kind of wireless telecommunication system and method for the implantable medical devices with arousal function, belongs to implantable medical devices technical field.Before communication, vitro program controlled system sends a kind of special wake-up signal to implantable medical devices, implantable medical devices receive wake-up signal in awake window and are waken up, both sides start to communicate, this ensure that when not communicated, the communicating circuit of implantable medical devices is fully powered-off, reduces power consumption during implantable medical devices major part normal use.
Description
Technical field
The invention belongs to implantable medical devices technical field, is related to a kind of wireless telecommunication system of implantable medical devices
And method.
Background technology
Implantable medical devices include pacemaker, defibrillator, brain pacemaker, nerve stimulator etc., they are current
The quality of life for the treatment of and improvement associated class patient, the optimal therapy for extending patient's service life.Since such medical instrument is implantation
Formula device, so will be by performing the operation in implantation human body, once implanted, to ensure that built-in type device is operated in most preferably
State, doctor can only be adjusted the parameters of instrument according to patient by way of wireless communication transmissions,
The patient information collected is transferred to vitro program controlled device, patient and implantation after observation implantable medical devices implantation at the same time
The state of apparatus.Each routine inspection, parameter adjustment and the monitoring of working status after apparatus implantation, are required for by external
Program control device is realized by the way of wireless communication.
With the continuous development of implantable medical devices, function it is gradual perfect, transmitted data amount gradually increases, especially
During the follow-up of patient, implantable medical devices feed back to the measurement of vitro program controlled device and amount of diagnostic information substantially increases
Greatly, further, since implantable medical devices use supplying cell finite capacity, in order to extend its service life, it is necessary to the greatest extent may be used
Energy ground reduces its and runs power consumption.The design of implantable medical devices and the respective communicating circuit of vitro program controlled device is meeting data
While the real-time and reliability requirement of transmission, it is necessary to meet the requirement for reducing implantable medical devices communication power consumption.
The content of the invention
It is an object of the invention to provide a kind of wireless telecommunication system of the implantable medical devices with arousal function, its
Pass through the arousal function of setting so that wireless telecommunication system may be at resting state under the conditions of communication, greatly reduce
The power consumption of wireless telecommunication system.
The present invention also aims to provide a kind of wireless telecommunication system of the implantable medical devices with arousal function
The means of communication, it can effectively realize the arousal function of the wireless telecommunication system of implantable medical devices, help to reduce wireless
The power consumption of communication system.
The present invention is to be achieved through the following technical solutions：
A kind of wireless telecommunication system of the implantable medical devices with arousal function, includes the body of implantable medical devices
External communicating circuit two parts of interior communicating circuit and vitro program controlled device；
Internal communicating circuit include first coil, wake-up module, the first data reception module, the first data transmission blocks,
Power control module and the first controller；
The output terminal of first coil is defeated with the input terminal of the first data reception module and the first data transmission blocks respectively
Enter end to be electrically connected, the output terminals of the output terminal of the first data reception module and the first data transmission blocks respectively with the first controller
Connection；
First controller connects the input terminal of the first data transmission blocks, the output terminal connection the of the first data transmission blocks
The input terminal of one coil；
Power control module is controlled with wake-up module, the first data reception module, the first data transmission blocks and first respectively
Device processed is electrically connected；First controller controls the power supply state of power control module, power control module control wake-up module, first
The power supply state of data reception module and the first data transmission blocks, when wake-up module, the first data reception module, the first data
When a module in sending module is in power-up state, two other module is in off-position；
When internal communicating circuit is in communication state, the wake-up that the outer communicating circuit of first coil energy receiving body is sent is believed
Number, and wake-up signal is transferred to the first controller by wake-up module, the first controller receives control volume after wake-up signal
Interior communicating circuit entry communication state.
Preferably, external communicating circuit includes signal strength detection module, the second coil, the second data reception module, the
The second device processed of two data transmission blocks, second source modular converter and control；Second coil respectively with the second data reception module,
Two data transmission blocks are electrically connected, and for the signal transmission that will be coupled into the second data reception module and reception and launch the
The signal of two data transmission blocks input；Signal strength detection module is electric with the second data reception module, second controller respectively
Connection, for detecting the signal strength in the second data reception module, and inputs second controller by result；Second controller point
It is not electrically connected with signal strength detection module, the second data reception module, the second data transmission blocks, for receiving and decoding
The signal of two data reception modules input obtains initial data, believes to the second data transmission blocks output data to be sent, reception
The result of number intensity detection module input and the signal amplification factor that the second data reception module is adjusted according to result；Second source
Modular converter is electrically connected with the second data reception module, the second data transmission blocks, signal strength detection module respectively, for inciting somebody to action
Power supply is converted to the power supply electricity needed for the second data reception module, the second data transmission blocks and signal strength detection module
Pressure and reference voltage.
Preferably, the wake-up module includes low-pass filter and the first hysteresis comparator, wherein, low-pass filter it is defeated
Enter end to be electrically connected with first coil, the output terminal of low-pass filter is electrically connected with the input terminal of the first hysteresis comparator, and first is slow
The output terminal of stagnant comparator is electrically connected with the first controller；The signal that first coil receives after low-pass filter filters again
Compare through the first hysteresis comparator, comparative result is transmitted directly to the first controller.
Preferably, before communication is established, internal communicating circuit is in dormancy shape；External communicating circuit is to internal communicating circuit
Waken up, awakening method is：
1) wake-up signal is sent by external communicating circuit at a certain time interval, until waking up successfully；
2) communicating circuit receives wake-up signal in awake window in vivo, then sends calling code；The awake window is body
The power-on time window of the wake-up module of interior communicating circuit；Call the device code that code is Implantable medical device；
3) external communicating circuit receives calling code, wakes up successfully, establishes communication.
Preferably, the wake-up signal is the set of pulses signal with defined amplitude, interval and pulsewidth.
Preferably, in step 2), internal communicating circuit is logical in vivo every certain time interval in a dormant state
The wake-up module of news circuit powers on a period of time, which is awake window；In awake window, call out
Module of waking up will be sent to the first controller of internal communicating circuit after the signal processing received；If the first controller judges to receive
To after wake-up signal, then control wake-up module to power off and be that the first data transmission blocks of internal communicating circuit power on, by first
Data transmission blocks send out calling code；After calling code transmission, the first data reception module of internal communicating circuit powers on.
Preferably, calling code includes the device code of unique mark Implantable medical device.
Preferably, in step 3), the external received calling code of communicating circuit docking is verified, and is sent out if verification is correct
Send command code；Internal communicating circuit receives command code, and after decoding, verifying, command code is returned again to external communicating circuit,
Then wake up successfully；If internal communicating circuit receives command code communication time-out or to command code check errors, terminating communication, body
Interior communicating circuit enters resting state.
Preferably, coding mode is：1 is encoded to " 01 ", and 0 is encoded to " 11 ".
Preferably, after external communicating circuit wakes up internal communicating circuit, when implantable medical devices need continuously
When sending mass data, data transmission step is：
1) communicating circuit is sent step by step after data are packed in vivo, i.e., after the data for often continuously transmitting N number of byte, into etc.
Treat the time；
2) external communicating circuit sends synchronizing signal M after the data of N number of byte are received；
3) within the stand-by period, the internal communicating circuit receiving body synchronizing signal M that communicating circuit is sent outside is simultaneously verified；
4) synchronizing signal verification is correct, then repeat step 1)~3)；Until all data transfers are completed；
Wherein, the stand-by period is 1~3ms；N is the integer more than zero；Synchronizing signal M is defined as the N number of byte number sent
According to low eight of verification sum.
Compared with prior art, the present invention has technique effect beneficial below：
A kind of wireless communication system of the implantable medical devices with arousal function, includes the body of implantable medical devices
External communicating circuit two parts of interior communicating circuit and vitro program controlled device；Internal communicating circuit includes first coil, wakes up mould
Block, the first data reception module, the first data transmission blocks, power control module and the first controller；It is logical that need not perform
During news task, internal communicating circuit is in communication state, and (the first data reception module, the first data transmission blocks are completely disconnected
Electricity), it can so significantly reduce the power consumption of internal communicating circuit；When needing to perform communication task, external communicating circuit is sent
Wake-up signal, which can be received by first coil and be transferred into the first controller by wake-up module, first
Controller then wakes up internal communicating circuit after wake-up signal is received, and performs communication task.In this way, the wireless communication system is being protected
When holding the communication state of low-power consumption, can entry communication state when needed, do not interfere with normal communication operation.Not only such as
This, power control module timesharing, alternatively power to wake-up module, the first data reception module, the first data transmission blocks, when
When a module in wake-up module, the first data reception module, the first data transmission blocks is in power-up state, two other
Module is in off-position, and that further reduces the power consumption of internal communicating circuit.To sum up, wireless telecommunications system provided by the invention
System, before communication, vitro program controlled device sends wake-up signal to implantable medical devices, and implantable medical devices are in awake window
Wake-up signal is received to be waken up, both sides start to communicate, this ensure that when not communicated, implantable medical devices
Internal communicating circuit part power-off (the first data reception module, the first data transmission blocks are fully powered-off, power control module and
The workload and working frequency of first controller are greatly reduced), when reducing implantable medical devices major part normal use
Power consumption, and then extend the service life of implantable medical devices.
The means of communication of wireless telecommunication system provided by the invention, before communication, internal communicating circuit is in dormancy shape；Body
Outer program control device sends wake-up signal to implantable medical devices, and implantable medical devices receive wake-up signal in awake window
It is waken up, both sides start to communicate, this ensure that when not communicated, the internal communicating circuit portion of implantable medical devices
(the first data reception module, the first data transmission blocks are fully powered-off, the work of power control module and the first controller for disjunction electricity
Work amount and working frequency are greatly reduced), power consumption during implantable medical devices major part normal use is reduced, and then extend
The service life of implantable medical devices.
Further, in communication process, a kind of special coding mode is defined according to the characteristics of hardware circuit, is used
Coding mode effectively reduce power consumption while significantly improve communication efficiency.
Brief description of the drawings
Fig. 1 is the implantable medical communication system overall schematic of the present invention.
Fig. 2 is the entire block diagram of Implanted medical system wireless telecommunication system.
Fig. 3 is wake-up signal schematic diagram.
Fig. 4 is awake window schematic diagram.
Fig. 5 is a kind of circuit diagram of external communicating circuit.
Fig. 6 is a kind of circuit diagram of communicating circuit in vivo.
1 is implantable medical devices, and 2 be internal communicating circuit, and 3 be vitro program controlled device, and 4 be external communicating circuit, and 5 are
Second source modular converter, 6 be first coil, and 7 be wake-up module, and 8 be the first data reception module, and 9 be the first data sending
Module, 10 be power control module, and 11 be the first controller, and 12 be level shifting circuit, and 13 be the second coil, and 14 is strong for signal
Detection module is spent, 15 be the second data reception module, and 16 be the second data transmission blocks, and 17 be second source modular converter, 18
For second controller.
Embodiment
With reference to specific embodiment, the present invention is described in further detail, it is described be explanation of the invention and
It is not to limit.
The present invention provides a kind of wireless communications method of implantable medical devices, Fig. 1 is the implantable medical of the present invention
Communication system overall schematic, includes two parts：Implantable medical devices 1, vitro program controlled device 3.Wherein, vitro program controlled dress
Put 3 external communicating circuit 4 and pass through wireless telecommunications with the internal communicating circuit 2 for the implantable medical devices 1 being implanted in human body
Mode carry out data exchange, complete to the operation such as the inquiring about of implantable medical devices 1, program-controlled.
Fig. 2 show the entire block diagram of Implanted medical system wireless telecommunication system, includes the body of implantable medical devices
4 two parts of interior communicating circuit 2 and the external communicating circuit of vitro program controlled system.
Communicating circuit 2 includes in implantable medical devices body：First coil 6, wake-up module 7, the first data reception module
8th, the first data transmission blocks 9,10 and first controller 11 of power control module.Wherein, wake-up module 7 is used for the outer journey of receiving body
The wake-up signal that control system is sent, and wake-up signal is transferred to the serial input port of the first controller 11；First data connect
Receive module 8 to be used to receive coupled signal in first coil 6, be filtered by filter circuit, comparator and shaping circuit, shaping
Processing, the serial ports receiving port that the digital signal that processing obtains is sent to the first controller 11 are decoded；First data are sent out
Module 9 is sent to launch after the encoded signal that first controller, 11 serial ports exports is amplified by first coil 6；Power supply control mould
Block 10 is used for controlling the power supply of wake-up module 7, the first data reception module 8 and the first data transmission blocks 9, using time sharing power supply
Control program, i.e. a particular moment are only individually powered for a module, and other two module is in off-position.
The external communicating circuit 4 of vitro program controlled device includes：Second coil 13, signal strength detection module 14, second count
According to receiving module 15, the second data transmission blocks 16, second source modular converter 17 and second controller 18.Wherein, signal is strong
Spend detection module 14 to be used to carry out the signal after filter and amplification in the second data reception module 15 two-way peak detection, obtain
The peak value and valley of signal, by the intensity come the shaping circuit of selective receiving circuit, to increase the reception of external communicating circuit 4
Distance；Second data reception module 15 is used to be filtered after amplification, shaping the signal on the second coil 13 to obtain digital letter
Number, then initial data is obtained by the decoding of second controller 18；Second data transmission blocks 16 are used to send second controller 18
Data-signal be amplified, then launched by the second coil 13；Second source modular converter 17 is used for power supply
Be converted to the supply voltage needed for the second data reception module 15, the second data transmission blocks 16 and signal strength detection module 14
And reference voltage.
Wherein, shaping electricity of the present invention for 15 afterbody of the first data reception module 8 and the first data reception module
The characteristics of road, is, it is specified that a kind of distinctive coding mode.Since the output characteristic of shaping circuit is that low level can only keep fixed
Time span, therefore, coding mode 1 is encoded to " 01 ", and 0 is encoded to " 11 ", is so not in " 00 " in communication process
State, such coding mode ensure that being transmitted with flank speed on this hardware foundation.Using this coding mode, ensure
The communication speed of communication system and average power consumption is effectively reduced, specifically, communication speed can reach 500bps and communication
Average power consumption is controlled below 100 μ A.Wherein, in order to reduce the overall power of communication system, implantable medical devices are extended
Service life, internal communicating circuit 2 is designed with resting state, when in a dormant state, the first control of internal communicating circuit 2
Device 11 is switched under low-power consumption mode, and controls the first data reception module 8 and the first data transmission blocks 9 to power off, while with
Certain of short duration time interval powers to wake-up module 7 and (opens awake window), detects whether to receive vitro program controlled system
The wake-up signal that the external communicating circuit of system is sent.If receiving signal, to the first control after the shaped processing of circuit of this signal
Device 11, after confirming that wake-up signal is correct by the first controller 11, internal communicating circuit is waken up, and by the of internal communicating circuit
One controller 11 produces a control command, controls wake-up module to power off by power control module, while control the first data
Sending module 9 is powered, and the first data transmission blocks 9 send calling code by first coil 13 to external communicating circuit 4, for ringing
Answer the wake-up signal of external communicating circuit 4.
Before communication is established, external communicating circuit 4 needs to wake up internal communicating circuit 2.Wake-up signal is by external
Second data transmission blocks 16 of communicating circuit 4 are transmitted in space by the second coil 13, as shown in figure 3, each group of wake-up
Signal is defined as amplitude and is X, at intervals of Y, pulsewidth is continuous multiple (1-10) pulse signals of Z, every group of wake-up signal interval
Time is T.In the transmission interval T of every group of wake-up signal, if the second data reception module 15 receives data, exit and call out
Awake pattern, and verify whether the calling code sent for internal communicating circuit 2, after verification is correct, the second data transmission blocks 16 are sent out
Send command code and start to communicate；If correspondingly, the second data reception module 15 does not have in the transmission interval T of every group of wake-up signal
Calling code is received, then cycles through wake-up signal, the calling code returned until receiving internal communicating circuit 2.
Before communication is established, in a dormant state, wait is waken up communicating circuit 2 in Implantable medical device body.
During resting state, wake-up module 7 works at a time interval, as shown in figure 4, every 7 power-on time of time T1 wake-up module
It is less than 0.2 μ A as awake window, the at this time average power consumption of internal communicating circuit 2 for t, time t.When in awake window, call out
The analog signal that module 7 of waking up collects first coil 6 is filtered, shaping, is sent to the first controller 11 and is judged.Such as
The first controller of fruit 11 judges after receiving correct wake-up signal that then internal communicating circuit 2 is waken up, power control module 10
Control wake-up module 7 powers off, and the first data transmission blocks 9 power on, and send calling code by the first data transmission blocks 9.Especially
Ground, calling code include the device code of unique mark Implantable medical device.
External communicating circuit 4 verifies the received calling code comprising device code, starts " to hold if verification is correct
Hand " process, sends user to internal communicating circuit 2 and specifies the corresponding command code of order, command code is defined as the number of a byte
According to；If check errors, return continues to send wake-up signal.Correspondingly, communicating circuit 2 passes through after calling code has been sent in vivo
Power control module 10 controls the first data transmission blocks 9 to power off, while the first data reception module 8 powers on, and receives above-mentioned body
The command code that outer communicating circuit 4 is sent, internal communicating circuit 2 are sent out by the first data again after decoding, verifying, by command code
Send module 9 to return to external communicating circuit 4, complete communication and " shake hands " process.
The external communicating circuit 4 of communicating pair and in vivo communicating circuit 2 communicate electricity in vivo after calling and " shaking hands " success
Road 2 is operated accordingly according to the command code received according to the communications protocol specified, and includes setting, the inside of program-controlled parameter
The transmission of telemetry, upgrading of system code etc..
In communication process, internal communicating circuit 2 is overtime in the event of check errors or communication, then terminating communication, the
One controller 11 cuts off the power supply of the first data reception module 8 and the first data transmission blocks 9 and recovers wake-up module 7 and powers,
The first controller 11 enters low-power consumption mode at the same time, until detecting that wake-up signal just starts new round communication again.
Wherein, for the data volume bigger that may relate in communication process and the situation of time longer interaction, consider
To timing skew caused by long-time, the one direction of big data quantity communication possibility, a kind of method of data-signal synchronization is devised：
First controller 11 of internal communicating circuit 2 is sent step by step after data are packed, i.e., after the data for often continuously transmitting N number of byte,
Wait 1ms, the synchronizing signal that the outer communicating circuit of receiving body is sent.External communicating circuit 4 is receiving the data of N number of byte at the same time
Afterwards, send synchronizing signal, synchronizing signal is low eight of verification sum of the N number of byte of this part, i.e., numerical value be 0x00 to 0xFF it
Between a byte data M.The controller 11 of internal communicating circuit 2 docks received synchronizing signal M and is verified, if just
Really, then continue to send the data of next group of N number of byte；If mistake is not received by synchronizing signal M, lastblock is resend
The data of N number of byte, each block number are remained unchanged time-out or mistake if receiving synchronizing signal M according at most sending twice, to external
Communicating circuit 4 returns to resting state after sending failure command, and wait is waken up next time.
The present invention provides a kind of wireless communications method of implantable medical devices, including the circuit structure of communication system,
Coil electromagnetism sensing communication modes, a kind of special coding mode, a kind of special communication wake-up mechanism, communicate during confession
Electric control method and a kind of signal synchronizing method, have remote communication distance, small power consumption, communication speed is fast, caloric value is small and circuit
The advantages of structure is relatively easy, extends the service life of implantable medical devices, has in implantable medical devices field wide
Wealthy application prospect.
As a kind of specific embodiment, Fig. 5 illustrates a kind of specific implementation of external communicating circuit 4, wherein body
Outer communicating circuit is by second controller 18, the second data reception module 15, (triode amplifies electricity to the second data transmission blocks 16
Road), signal strength detection circuit (as signal strength detection module 14), signal strength indicator circuit, second source conversion electricity
Road (as second source modular converter 17) and 12 and second coil 13 of level shifting circuit are formed.
Second data reception module 15 is made of filter amplifier, the second hysteresis comparator, the second shaping circuit.Receiving
During, when the second coil 13 receives signal by coupled modes, filtered amplifier is filtered signal amplification, then
The numeral that obtaining second controller 18 to signal progress shaping by the second hysteresis comparator and the second shaping circuit can identify is believed
Number, received data are finally docked by second controller 18 and are decoded to obtain initial data.Meanwhile second controller 18 can also
The output of filter amplifier is enough adaptively adjusted, with the data receiver suitable for different distance, and enhances the anti-dry of circuit
Immunity.In data procedures are received, the transmitting pin of second controller 18 remains low level, makes the triode of radiating circuit
Cut-off state is in, so as to close emission function.
While performing receive capabilities in vitro, output signal of the signal strength detection circuit to filter amplifier carries out peak
It is worth detection, after via controller carries out AD sampling processings, received signal strength, signal strength is indicated by signal strength indicator circuit
Indicating circuit is made of one group of LED.
When performing sending function in vitro, second controller 18 is according to fixed format sent out after carrying out specific coding to data
Go out, be amplified through transistor amplifier pulse signals, then export to the second coil 13.In data procedures are launched, by
The software control of second controller 18 disconnects the power supply of the second data reception module 15, avoids the second data reception module 15 from occurring
Receive by mistake.
After the power is turned on, its second data transmission blocks 16 sends what number was fixed to external communicating circuit 4 to internal communicating circuit 2
Wake-up signal, wake-up signal are made of a set of pulses, and the width of pulse immobilizes, so that internal communicating circuit 2 is believed waking up
Number confirmed.The external wake-up signal that sends every time will connect the second data reception module 15 afterwards, wait and return to letter in vivo
Breath, if receiving the message returned in vivo in setting time, carries out data exchange according to agreement in vitro with vivo.If return in vivo
Message time-out is returned, then continues to send wake-up signal in vitro.
Fig. 6 illustrates a kind of specific implementation of communicating circuit 2 in vivo, is generally divided into the first controller 11, power supply
9 four control module 10, the first data reception module 8, the first data transmission blocks parts.Wherein power control module 10 is responsible for
The break-make of communicating circuit power supply, and control the time sharing power supply to the first data reception module 8, the first data transmission blocks 9；First
Data reception module 8 be responsible for received coupled signal in first coil 6 is filtered, Shape correction；First data sending mould
Block 9 is responsible for being amplified the data that the first controller 11 is sent and by first coil 6 being launched.
Power control module 10 divides for communicating circuit master switch and transmitting/reception power switching switch.When internal communication electricity
When road 2 is not waken up, communicating circuit master switch is off, at this time the first data reception module 8, the first data sending
9 pieces of module is all in off-position.After system is waken up, communicating circuit master switch closure, the first controller 11 is to launching/connecing
Receive power switching switch to be controlled, selected according to communication succession to the first data reception module 8 or the first data transmission blocks 9
Power supply.
Before communication is established, the first controller 11 is powered and is held using Fixed Time Interval as the first data reception module 8
Continue an of short duration time, if first coil 6 receives the wake-up signal sent in vitro in time period, the signal is through low pass filtered
The first controller 11 is sent to after ripple device and the processing of the second hysteresis comparator, the first controller 11 carries out obtained signal true
Recognize, if confirming as wake-up signal, the first controller 11 is waken up and starts communication process at once.If do not called out in time period
Wake up, then communicating circuit master switch is disconnected after this period, and wait timing next time to open awake window.
When performing internal receive capabilities, powered by power control module 10 for the first data reception module 8, first is slow
Stagnant comparator and the first shaping circuit power on, while the first power-switching circuit (as the first power conversion module 5) will power
Power supply is converted to reference voltage Vref, and comparison voltage is provided for the first hysteresis comparator.First coil 6 is received by inductive coupling
The signal transmitted to the second coil 13 of external communicating circuit 4, is filtered after voltage Vref liftings by low-pass filter
Processing, then the numeral letter that shaping obtains the first controller 11 and can identify is carried out by the first hysteresis comparator and the first shaping circuit
Number, received and decoded by the serial ports of the first controller 11.Wherein, the selection of the first hysteresis comparator comparison voltage has two kinds
Scheme, first, comparison voltage is directly grounded, input signal is compared with no-voltage；Second, comparison voltage meets Vref, input signal with
Vref compares, another input terminal of hysteresis comparator is also required to be raised to Vref, and scheme two is preferred solution, as shown in Figure 6.
When performing intra-body data emission function, powered by power control module 10 for the first data transmission blocks 9, the
One controller 11 encodes the data that send of needs, by the first data transmission blocks 9 (metal-oxide-semiconductor amplifying circuit) by data
Space is transmitted to by first coil 6, data are received in certain distance by the direct-coupled mode of coil by the second coil 13
Arrive.
In communication process, if the first controller 11 detects that mistake, terminating communication occur for communication, and first is cut off
The power supply of 8 and first data transmission blocks 9 of data reception module with achieve the purpose that save power consumption, while the first controller 11 into
Enter low-power consumption mode, until detecting that wake-up signal just opens the power supply of the first data transmission blocks 9 again.In communication process
Any moment, transmitting/reception power switching switch only can stably, alternatively connect the first data reception module 8 or the
The power supply of one data transmission blocks 9, the first data reception module 8 and the first data transmission blocks 9 can't be opened at the same time, with most
The reduction power consumption of limits, extends the working life of whole implantable medical devices.
Claims (10)
1. a kind of wireless telecommunication system of the implantable medical devices with arousal function, it is characterised in that cured including implanted
Treat the internal communicating circuit (2) of apparatus (1) and external communicating circuit (4) two parts of vitro program controlled device (3)；
Internal communicating circuit (2) includes first coil (6), wake-up module (7), the first data reception module (8), the first data hair
Send module (9), power control module (10) and the first controller (11)；
The output terminal of first coil (6) input terminal and the first data transmission blocks (9) with the first data reception module (8) respectively
Input terminal be electrically connected, the output terminal of the first data reception module (8) and the output terminal of the first data transmission blocks (9) respectively with
First controller (11) connects；
First controller (11) connects the input terminal of the first data transmission blocks (9), the output terminal of the first data transmission blocks (9)
Connect the input terminal of first coil (6)；
Power control module (10) respectively with wake-up module (7), the first data reception module (8), the first data transmission blocks (9)
It is electrically connected with the first controller (11)；The power supply state of first controller (11) control power control module (10), power supply control
The power supply state of module (10) control wake-up module (7), the first data reception module (8) and the first data transmission blocks (9), when
A module in wake-up module (7), the first data reception module (8), the first data transmission blocks (9) is in power-up state
When, two other module is in off-position；
When internal communicating circuit (2) is in communication state, what the outer communicating circuit (4) of first coil (6) energy receiving body was sent calls out
Awake signal, and wake-up signal is transferred to the first controller (11) by wake-up module (7), the first controller (11), which receives, calls out
Communicating circuit (2) entry communication state in control volume after awake signal.
2. the wireless telecommunication system of the implantable medical devices with arousal function as described in right 1, it is characterised in that external
Communicating circuit (4) includes signal strength detection module (14), the second coil (13), the second data reception module (15), the second number
According to the second device (18) processed of sending module (16), second source modular converter (17) and control；Second coil (13) is counted with second respectively
It is electrically connected according to receiving module (15), the second data transmission blocks (16), the signal transmission for will be coupled into connects to the second data
Receive module (15) and receive and launch the signal of the second data transmission blocks (16) input；Signal strength detection module (14) point
It is not electrically connected with the second data reception module (15), second controller (18), for detecting in the second data reception module (15)
Signal strength, and by result input second controller (18)；Second controller (18) respectively with signal strength detection module
(14), the second data reception module (15), the second data transmission blocks (16) are electrically connected, and are connect for receiving and decoding the second data
The signal for receiving module (15) input obtains initial data, believes to the second data transmission blocks (16) output data to be sent, reception
The result of number intensity detection module (14) input and the signal amplification factor that the second data reception module (15) is adjusted according to result；
Second source modular converter (17) respectively with the second data reception module (15), the second data transmission blocks (16), signal strength
Detection module (14) is electrically connected, for power supply to be converted to the second data reception module (15), the second data transmission blocks
(16) and supply voltage and reference voltage needed for signal strength detection module (14).
3. the wireless telecommunication system of the implantable medical devices with arousal function as described in right 1, it is characterised in that described
Wake-up module (7) includes low-pass filter and the first hysteresis comparator, wherein, the input terminal and first coil of low-pass filter
(6) be electrically connected, the output terminal of low-pass filter is electrically connected with the input terminal of the first hysteresis comparator, the first hysteresis comparator it is defeated
Outlet is electrically connected with the first controller (11)；The signal that first coil (6) receives is after low-pass filter filters again through
One hysteresis comparator compares, and comparative result is transmitted directly to the first controller (11).
A kind of 4. means of communication of the wireless telecommunication system of the implantable medical devices with arousal function, it is characterised in that
Before communication is established, internal communicating circuit (2) is in dormancy shape；External communicating circuit (4) to internal communicating circuit (2) into
Row wakes up, and awakening method is：
1) wake-up signal is sent by external communicating circuit (4) at a certain time interval, until waking up successfully；
2) communicating circuit (2) receives wake-up signal in awake window in vivo, then sends calling code；The awake window is internal
The power-on time window of the wake-up module (7) of communicating circuit (2)；Call the device code that code is Implantable medical device；
3) external communicating circuit (4) receives calling code, wakes up successfully, establishes communication.
5. the means of communication of the wireless telecommunication system of the implantable medical devices with arousal function as claimed in claim 4,
It is characterized in that,
The wake-up signal is the set of pulses signal with defined amplitude, interval and pulsewidth.
6. the means of communication of the wireless telecommunication system of the implantable medical devices with arousal function as claimed in claim 4,
It is characterized in that,
In step 2), internal communicating circuit (2) in a dormant state, every certain time interval be internal communicating circuit
(2) wake-up module (7) powers on a period of time, which is awake window；In awake window
Interior, wake-up module (7) will be sent to the first controller (11) of internal communicating circuit (2) after the signal processing received；If the
One controller (11) judged after receiving wake-up signal, then controls wake-up module (7) to power off and for the of internal communicating circuit (2)
One data transmission blocks (9) power on, and calling code is sent out by the first data transmission blocks (9)；After calling code transmission, communication in vivo
The first data reception module (8) of circuit (2) powers on.
7. the means of communication of the wireless telecommunication system of the implantable medical devices with arousal function as claimed in claim 6,
It is characterized in that, calling code includes the device code of unique mark implantable medical devices (1) device.
8. the means of communication of the wireless telecommunication system of the implantable medical devices with arousal function as claimed in claim 4,
It is characterized in that, in step 3), the external received calling code of communicating circuit (4) docking is verified, and is sent out if verification is correct
Send command code；Internal communicating circuit (2) receives command code, and after decoding, verifying, command code is returned again to external communication electricity
Road (4), then wake up successfully；If internal communicating circuit (2) receives command code communication time-out or to command code check errors, whole
Only communicate, internal communicating circuit (2) enters resting state.
9. the means of communication of the wireless telecommunication system of the implantable medical devices with arousal function as claimed in claim 4,
It is characterized in that, coding mode is：1 is encoded to " 01 ", and 0 is encoded to " 11 ".
10. the means of communication of the wireless telecommunication system of the implantable medical devices with arousal function as claimed in claim 4,
It is characterized in that,
After external communicating circuit (4) wakes up internal communicating circuit (2), when implantable medical devices (1) need continuous hair
When sending mass data, data transmission step is：
1) communicating circuit (2) is sent step by step after data are packed in vivo, i.e., after the data for often continuously transmitting N number of byte, into etc.
Treat the time；
2) external communicating circuit (4) sends synchronizing signal M after the data of N number of byte are received；
3) within the stand-by period, internal communicating circuit (2) the receiving body synchronizing signal M that communicating circuit (4) is sent outside simultaneously carries out school
Test；
4) synchronizing signal verification is correct, then repeat step 1)~3)；Until all data transfers are completed；
Wherein, the stand-by period is 1~3ms；N is the integer more than zero；Synchronizing signal M is defined as the N number of byte data sent
Verify low eight of sum.
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| CN112468189A (en) * | 2020-12-31 | 2021-03-09 | 常州瑞神安医疗器械有限公司 | Implantable medical device wireless near-field communication slave machine |
| CN112672411A (en) * | 2020-12-11 | 2021-04-16 | 苏州景昱医疗器械有限公司 | Method and system for adaptively adjusting implant transmitting power |
| CN112754501A (en) * | 2021-02-05 | 2021-05-07 | 杭州诺为医疗技术有限公司 | Low-power-consumption implantable closed-loop self-response nerve stimulation system |
| CN114900206A (en) * | 2022-05-09 | 2022-08-12 | 北京芯联心科技发展有限公司 | In-vivo and in-vitro wireless communication system and power supply and communication time-sharing multiplexing method thereof |
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