CN107894501A - A kind of contact lens kit and its application - Google Patents
A kind of contact lens kit and its application Download PDFInfo
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- CN107894501A CN107894501A CN201711078479.0A CN201711078479A CN107894501A CN 107894501 A CN107894501 A CN 107894501A CN 201711078479 A CN201711078479 A CN 201711078479A CN 107894501 A CN107894501 A CN 107894501A
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
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Abstract
The present invention provides a kind of contact lens kit and its application, the contact lens kit includes light selective penetrated property contact lens, and the smooth selective penetrated property contact lens includes full impregnated light contact lens, light deprives contact lens, reveal the green light contact lens and saturating blue light contact lens.When the contact lens kit of the present invention is applied in the regulation and control experiment of animal model corneal light, can meet with group animal Different Individual do not share the same light input and same experimental animal bilateral retina do not share the same light input the needs of, do not shared the same light input when, without using extra special light sources respectively, it can ensure that all zoopery environment are identical, avoid because experimental situation is different and caused by influence, reduce experimental cost and Operating Complexity, it is difficult that do not shared the same light to same group animal Different Individual input or input of not shared the same light to same animal bilateral retina are realized under the conditions of of the same race to solve the problems, such as prior art.
Description
Technical field
The invention belongs to technical field of biological materials, is related to a kind of contact lens kit and its application.
Background technology
Light be all for most organisms it is necessary, just in biological chain energy final source, biology has
Energy almost all necessary to body directly or indirectly derives from daylight.And for animal especially mammal,
Light is not only that it provides final energy, and energetic supersession, behavior, life cycle and geographical distribution for animal organisms etc.
There is direct or indirect influence.
Clinically, light therapy (Light therapy) is as a kind of new treatment means, because its is easy to use, valency
The advantages that lattice are cheap, Small side effects is using more and more extensive.Wherein to essences such as depression, rhythm disorder, sleep-disorder, chronic aches
The effect of refreshing disorder disease light treatment is especially pronounced.And find that the light of different wave spectrums is for difference according to current current research
Phrenoblabia, its therapeutic effect is also different.Such as blue light is controlled for depression positive effect, green glow for chronic ache
Therapeutic effect is obvious etc..But for phrenoblabia light treatment technical principle be all it is similar, i.e., light by with retina (eye
Eyeball) contact, inputted from vision system and then the analysis of triggering nervous centralis and integration produce different physiological reactions, controlled so as to reach
The effect for the treatment of.Although light therapy is clinically using relatively broad, at present for Study on mechanism therein not
It is clear from, also has increasing scientific research, clinical workers to add the research for light therapy mechanism.For grinding for its mechanism
Study carefully and be advantageous to our more scientific and effective this method of utilization.
In order to preferably study the mechanism of light therapy, Many researchers are studied by animal pattern experiment, but
At present in its research method, there is it is more the problem of, such as when needing to the input of the retinas of same group of different animals not
With light when dealt with, it is necessary to which Different Individual is separated, it is at this moment not only cumbersome, and with group animal between other realities
Test condition (such as temperature, noise, whether stress wait) and easily produce fluctuation.And for example when same animal bilateral retina needs are defeated
When entering different light, to meet two eyes and meanwhile input different light sources operation it is extremely complex, and each other easily by shadow
Ring, and cost is higher；When needing the light input of different wave spectrums, a variety of different light sources need to be built, at this moment can be produced bigger
Cost input.
Therefore, need preferably solve mesh for animal model corneal light regulation and control experimental study exploitation one kind in the art
The product or method of preceding the problem of existing.
The content of the invention
In view of the shortcomings of the prior art, it is an object of the invention to provide a kind of contact lens kit and its application.
To reach this goal of the invention, the present invention uses following technical scheme：
On the one hand, the present invention provides a kind of contact lens kit, and the contact lens kit selects including light
Permeability contact lens, the smooth selective penetrated property contact lens includes full impregnated light contact lens, light is deprived cornea and connect
Touch mirror, reveal the green light contact lens and saturating blue light contact lens.
Preferably, the smooth selective penetrated property contact lens is spherical mirror.
Preferably, the material for preparing of the smooth selective penetrated property contact lens is methyl methacrylate.
In the present invention, the material for preparing of the smooth selective penetrated property contact lens is not limited to methyl methacrylate
Ester, other are for experimental animal is harmless or the less material of infringement can also be used for the making of the present invention.Material described above
For gas permeability hard Contact Lens, damage or stress reaction will not be produced to experimental animal eyes.
The full impregnated light contact lens is transparency cornea contact lense in the present invention, i.e., all wave band light sources are all in white light
It can pass through.
Preferably, it is light impermeability contact lens that the light, which deprives contact lens, is in transparency cornea contact lense
Surface coating light-proof material is prepared.
Preferably, the light contact lens that reveals the green is the material in the selective light that reveals the green of transparency cornea contact lense surface coating
Expect and obtain.
Preferably, the blue light contact lens is the material in the saturating blue light of transparency cornea contact lense surface coating selectivity
Expect and obtain.
Preferably, the smooth selective penetrated property contact lens is in spherical crown shape, and the basal diameter of spherical crown is 7.1 ± 0.3mm,
A height of 3.3 ± 0.15mm.
Certainly, in the present invention it is possible to the light selective penetrated property that other adapt to specification according to the different choice of experimental animal
Contact lens.
On the other hand, regulate and control the invention provides contact lens kit as described above in animal model corneal light real
Application in testing.
Preferably, when same group animal Different Individual needs not share the same light input, using in the contact lens kit
Different contact lens realize.
Preferably, when a same animal bilateral retina need to not share the same light input, using in the contact lens kit
Different contact lens realize.
The different contact lens be full impregnated light contact lens, the light included in kit deprive contact lens,
Reveal the green light contact lens and saturating blue light contact lens, can carry out selection use as needed.
In the present invention, can be met using the different contact lens in the contact lens kit dynamic with group
Thing Different Individual is not shared the same light the demand of input, it is ensured that experimental animal conditional consistency, without using special wave spectrum light source or
Animal is put into the light input operation of the different requirements of darkroom progress, can avoid animal being divided into different groups, is put into different experiments sky
In give different light sources and caused by experimental situation difference.For same experimental animal, prior art is difficult reality
Now same animal bilateral retina is not shared the same light input, and solve this using the contact lens kit of the present invention
One problem.
For example, using the contact lens kit of the present invention, when the side retina light requirement input of animal, opposite side is not
Light requirement only needs to load onto lighttight light in side when inputting deprives contact lens, and opposite side loads onto full impregnated light contact lens
It can complete.
Using the contact lens kit of the present invention, need not be separated processing to experimental animal can complete, can
Ensure with group animal when retina receives light input, other being consistent property of physiological condition.
Using the contact lens kit of the present invention, without building extra special light sources, and light selectivity Corneal Contact
Mirror cost is relatively low, can be reused after specially treated, therefore cost is relatively low, easy to use.
Preferably, the animal pattern in the animal model corneal light regulation and control experiment is adult SD rats.It is but of the invention
It is not limited to this kind of experimental animal.
Relative to prior art, the invention has the advantages that：
The present invention contact lens kit can meet with group animal Different Individual do not share the same light input and same
Experimental animal bilateral retina is not shared the same light the demand of input, do not shared the same light input when, without using extra special light sources respectively,
Can ensure that all zoopery environment are identical, avoid because experimental situation is different and caused by influence, reduce experimental cost and
Operating Complexity, solve prior art be difficult under the conditions of of the same race realize to group animal Different Individual do not share the same light input or
To same animal bilateral retina do not shared the same light input the problem of.For animal model test research provide it is simpler,
Reliably, efficient laboratory facilities.
Brief description of the drawings
Fig. 1 is the light selective penetrated property contact lens structural representation included in contact lens kit of the present invention,
Wherein A is full impregnated light contact lens, and B is that light deprives contact lens, and C is the light contact lens that reveals the green, and D is saturating blue light cornea
Contact lense.
Fig. 2 is the schematic diagram that experimental animal wears smooth selective penetrated property contact lens of the present invention.
Fig. 3 be common white light source as incident light source when full impregnated light contact lens, light deprive contact lens, reveal the green
The printing opacity situation schematic diagram of light contact lens and saturating blue light contact lens.
Embodiment
Technical scheme is further illustrated below by embodiment.Those skilled in the art should be bright
, the embodiment be only to aid in understand the present invention, be not construed as to the present invention concrete restriction.
Embodiment 1
In the present embodiment, there is provided contact lens kit include light selective penetrated property contact lens, such as Fig. 1 institutes
Show, the smooth selective penetrated property contact lens includes full impregnated light contact lens (A), light is deprived contact lens (B), revealed the green
Light contact lens (C) and saturating blue light contact lens (D).
Full impregnated light contact lens (A), light deprive contact lens (B), reveal the green light contact lens (C) and saturating blue light angle
Film contact lense (D) is curved mirror, and in spherical crown shape, the basal diameter of spherical crown is 7.1 ± 0.3mm, a height of 3.3 ± 0.15mm, its
It is methyl methacrylate to prepare material.
Using the contact lens kit adult SD rats are carried out with light input experiment, when being tested, in order to
Retina input institute light requirement to experimental animal, smooth selective penetrated property Corneal Contact of the present invention is worn to experimental animal
Mirror, light selective penetrated property contact lens is attached to experimental animal intraocular with obtuse angle surgical forceps, Corneal Contact (such as pin with eyeball
The experimental animal stronger to stress reaction, slight anesthesia in advance can be done before contact lens is filled), as Fig. 2 is dynamic for experiment
Thing wears the schematic diagram of described light selective penetrated property contact lens.As shown in figure 3, light source selects commonly white in an experiment
Light source is as incident light source, and animal Different Individual is needed to carry out white light, light is deprived, green glow and blue light with organizing, using Corneal Contact
Full impregnated light contact lens, light in mirror kit deprives contact lens, reveal the green light contact lens and saturating blue light cornea connects
Tactile mirror allows to deprive different animals individual input white light, light, green glow and blue light.
Embodiment 2
In the present embodiment, there is provided contact lens kit include light selective penetrated property contact lens, such as Fig. 1 institutes
Show, the smooth selective penetrated property contact lens includes full impregnated light contact lens (A), light is deprived contact lens (B), revealed the green
Light contact lens (C) and saturating blue light contact lens (D).
Full impregnated light contact lens (A), light deprive contact lens (B), reveal the green light contact lens (C) and saturating blue light angle
Film contact lense (D) is curved mirror, and in spherical crown shape, the basal diameter of spherical crown is 7.1 ± 0.3mm, a height of 3.3 ± 0.15mm, its
It is methyl methacrylate to prepare material.
Using the contact lens kit adult SD rats are carried out with light input experiment, when being tested, in order to
Retina input institute light requirement to experimental animal, smooth selective penetrated property Corneal Contact of the present invention is worn to experimental animal
Mirror, light selective penetrated property contact lens is attached to experimental animal intraocular with obtuse angle surgical forceps, Corneal Contact (such as pin with eyeball
The experimental animal stronger to stress reaction, slight anesthesia in advance can be done before contact lens is filled), as Fig. 2 is dynamic for experiment
Thing wears the schematic diagram of described light selective penetrated property contact lens.Light source selects common white light source to be used as in an experiment
Light source is penetrated, it is necessary to carry out white light respectively to same animal bilateral retina and light deprives input to observe its physiological reaction, should
Contact lens is deprived with full impregnated light contact lens, the light in contact lens kit to wear to the left side of the animal and the right side
On side view nethike embrane, realize and white light is inputted respectively to left side and right side retina and light is deprived.
Embodiment 3
In the present embodiment, there is provided contact lens kit include light selective penetrated property contact lens, such as Fig. 1 institutes
Show, the smooth selective penetrated property contact lens includes full impregnated light contact lens (A), light is deprived contact lens (B), revealed the green
Light contact lens (C) and saturating blue light contact lens (D).
Full impregnated light contact lens (A), light deprive contact lens (B), reveal the green light contact lens (C) and saturating blue light angle
Film contact lense (D) is curved mirror, and in spherical crown shape, the basal diameter of spherical crown is 7.1 ± 0.3mm, a height of 3.3 ± 0.15mm, its
It is methyl methacrylate to prepare material.
Using the contact lens kit adult SD rats are carried out with light input experiment, when being tested, in order to
Retina input institute light requirement to experimental animal, smooth selective penetrated property Corneal Contact of the present invention is worn to experimental animal
Mirror, light selective penetrated property contact lens is attached to experimental animal intraocular with obtuse angle surgical forceps, Corneal Contact (such as pin with eyeball
The experimental animal stronger to stress reaction, slight anesthesia in advance can be done before contact lens is filled), as Fig. 2 is dynamic for experiment
Thing wears the schematic diagram of described light selective penetrated property contact lens.Light source selects common white light source to be used as in an experiment
Light source is penetrated, it is necessary to carry out green glow and blue light input respectively to same animal bilateral retina to observe its physiological reaction, is applied
The light contact lens that reveals the green, saturating blue light contact lens in contact lens kit are worn to the left side of the animal and right side
On retina, realize and green glow and blue light are inputted respectively to left side and right side retina.
Embodiment 4
In the present embodiment, there is provided contact lens kit include light selective penetrated property contact lens, such as Fig. 1 institutes
Show, the smooth selective penetrated property contact lens includes full impregnated light contact lens (A), light is deprived contact lens (B), revealed the green
Light contact lens (C) and saturating blue light contact lens (D).
Full impregnated light contact lens (A), light deprive contact lens (B), reveal the green light contact lens (C) and saturating blue light angle
Film contact lense (D) is curved mirror, and in spherical crown shape, the basal diameter of spherical crown is 7.1 ± 0.3mm, a height of 3.3 ± 0.15mm, its
It is methyl methacrylate to prepare material.
Using the contact lens kit adult SD rats are carried out with light input experiment, when being tested, in order to
Retina input institute light requirement to experimental animal, smooth selective penetrated property Corneal Contact of the present invention is worn to experimental animal
Mirror, light selective penetrated property contact lens is attached to experimental animal intraocular with obtuse angle surgical forceps, Corneal Contact (such as pin with eyeball
The experimental animal stronger to stress reaction, slight anesthesia in advance can be done before contact lens is filled), as Fig. 2 is dynamic for experiment
Thing wears the schematic diagram of described light selective penetrated property contact lens.Light source selects common white light source to be used as in an experiment
Light source is penetrated, it is necessary to carry out white light and blue light input respectively to same animal bilateral retina to observe its physiological reaction, is applied
Full impregnated light contact lens, saturating blue light contact lens in contact lens kit are worn to the left side of the animal and right side
On retina, realize and white light and blue light are inputted respectively to left side and right side retina.
Embodiment 5
In the present embodiment, there is provided contact lens kit include light selective penetrated property contact lens, such as Fig. 1 institutes
Show, the smooth selective penetrated property contact lens includes full impregnated light contact lens (A), light is deprived contact lens (B), revealed the green
Light contact lens (C) and saturating blue light contact lens (D).
Full impregnated light contact lens (A), light deprive contact lens (B), reveal the green light contact lens (C) and saturating blue light angle
Film contact lense (D) is curved mirror, and in spherical crown shape, the basal diameter of spherical crown is 7.1 ± 0.3mm, a height of 3.3 ± 0.15mm, its
It is methyl methacrylate to prepare material.
Using the contact lens kit adult SD rats are carried out with light input experiment, when being tested, in order to
Retina input institute light requirement to experimental animal, smooth selective penetrated property Corneal Contact of the present invention is worn to experimental animal
Mirror, light selective penetrated property contact lens is attached to experimental animal intraocular with obtuse angle surgical forceps, Corneal Contact (such as pin with eyeball
The experimental animal stronger to stress reaction, slight anesthesia in advance can be done before contact lens is filled), as Fig. 2 is dynamic for experiment
Thing wears the schematic diagram of described light selective penetrated property contact lens.Light source selects common white light source to be used as in an experiment
Light source is penetrated, it is necessary to carry out white light and blue light input respectively to same animal bilateral retina to observe its physiological reaction, is applied
Full impregnated light contact lens, the light contact lens that reveals the green in contact lens kit are worn to the left side of the animal and right side
On retina, realize and white light and green glow are inputted respectively to left side and right side retina.
The present invention illustrates the contact lens kit of the present invention and its application by above-described embodiment, but the present invention is simultaneously
Above-described embodiment is not limited to, that is, does not mean that the present invention has to rely on above-described embodiment and could implemented.Art
Technical staff it will be clearly understood that any improvement in the present invention, equivalence replacement and auxiliary element to raw material selected by the present invention
Addition, selection of concrete mode etc., within the scope of all falling within protection scope of the present invention and disclosing.
Claims (10)
1. a kind of contact lens kit, it is characterised in that the contact lens kit includes light selective penetrated property angle
Film contact lense, the smooth selective penetrated property contact lens includes full impregnated light contact lens, light is deprived contact lens, revealed the green
Light contact lens and saturating blue light contact lens.
2. contact lens kit according to claim 1, it is characterised in that the smooth selective penetrated property Corneal Contact
Mirror is spherical mirror.
3. contact lens kit according to claim 1 or 2, it is characterised in that the smooth selective penetrated property cornea
The material for preparing of contact lense is methyl methacrylate.
4. the contact lens kit according to any one of claim 1-3, it is characterised in that full impregnated light Corneal Contact
Mirror is transparency cornea contact lense.
5. the contact lens kit according to any one of claim 1-4, it is characterised in that the light deprives cornea
Contact lense is light impermeability contact lens, is prepared in transparency cornea contact lense surface coating light-proof material；
Preferably, it is described reveal the green light contact lens be transparency cornea contact lense surface coating selectivity reveal the green light material and
Obtain；
Preferably, the blue light contact lens be transparency cornea contact lense surface coating selectivity thoroughly blue light material and
Obtain.
6. the contact lens kit according to any one of claim 1-5, it is characterised in that the light selection passes through
Property contact lens is in spherical crown shape, and the basal diameter of spherical crown is 7.1 ± 0.3mm, a height of 3.3 ± 0.15mm.
7. the contact lens kit according to any one of claim 1-6 is in the regulation and control experiment of animal model corneal light
Application.
8. application according to claim 7, it is characterised in that when same group animal Different Individual needs not share the same light input,
Realized using the different contact lens in the contact lens kit.
9. the application according to claim 7 or 8, it is characterised in that need to not be shared the same light input when with an animal bilateral retina
When, realized using the different contact lens in the contact lens kit.
10. according to the application any one of claim 7-9, it is characterised in that the animal model corneal light regulation and control are real
Animal pattern in testing is adult SD rats.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711078479.0A CN107894501A (en) | 2017-11-06 | 2017-11-06 | A kind of contact lens kit and its application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711078479.0A CN107894501A (en) | 2017-11-06 | 2017-11-06 | A kind of contact lens kit and its application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107894501A true CN107894501A (en) | 2018-04-10 |
Family
ID=61804119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711078479.0A Pending CN107894501A (en) | 2017-11-06 | 2017-11-06 | A kind of contact lens kit and its application |
Country Status (1)
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| CN (1) | CN107894501A (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1036272A (en) * | 1987-11-30 | 1989-10-11 | 动物镜片有限公司 | The contact lenses and the manufacture method thereof that are used for animal |
| WO2007103310A2 (en) * | 2006-03-07 | 2007-09-13 | Qd Vision, Inc. | An article including semiconductor nanocrystals |
| CN101938935A (en) * | 2008-02-07 | 2011-01-05 | 杰克·格鲁伯 | Retinal melatonin suppressor comprising a filter layer |
| CN102791297A (en) * | 2010-03-08 | 2012-11-21 | 诺瓦提斯公司 | Active oxygen disinfection system and use thereof |
| CN103338816A (en) * | 2011-02-04 | 2013-10-02 | 庄臣及庄臣视力保护公司 | Apparatus and method for formation of an energized ophthalmic device for light therapy |
| CN104069588A (en) * | 2013-03-15 | 2014-10-01 | 庄臣及庄臣视力保护公司 | Method and device for monitoring and treatment of seasonal affective disorder |
| CN107272223A (en) * | 2006-11-28 | 2017-10-20 | 高性能光学公司 | The high performance selective light wavelength filtering of improved contrast sensitivity is provided |
-
2017
- 2017-11-06 CN CN201711078479.0A patent/CN107894501A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1036272A (en) * | 1987-11-30 | 1989-10-11 | 动物镜片有限公司 | The contact lenses and the manufacture method thereof that are used for animal |
| WO2007103310A2 (en) * | 2006-03-07 | 2007-09-13 | Qd Vision, Inc. | An article including semiconductor nanocrystals |
| CN107272223A (en) * | 2006-11-28 | 2017-10-20 | 高性能光学公司 | The high performance selective light wavelength filtering of improved contrast sensitivity is provided |
| CN101938935A (en) * | 2008-02-07 | 2011-01-05 | 杰克·格鲁伯 | Retinal melatonin suppressor comprising a filter layer |
| CN102791297A (en) * | 2010-03-08 | 2012-11-21 | 诺瓦提斯公司 | Active oxygen disinfection system and use thereof |
| CN103338816A (en) * | 2011-02-04 | 2013-10-02 | 庄臣及庄臣视力保护公司 | Apparatus and method for formation of an energized ophthalmic device for light therapy |
| CN104069588A (en) * | 2013-03-15 | 2014-10-01 | 庄臣及庄臣视力保护公司 | Method and device for monitoring and treatment of seasonal affective disorder |
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Application publication date: 20180410 |