CN107889996A - 一种改善记忆的保健食品及其制备方法 - Google Patents
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Abstract
本发明提供一种改善记忆的保健食品，它由如下重量份数的原料制备得到：白芷20‑30份、百合15‑25份、佛手10‑15份、茯苓10‑25份、荷叶10‑20份、火麻仁10‑15份、玫瑰花5‑10份，并采用了相应的制备方法，本发明具有改善记忆功效。
Description
技术领域
本发明属于中医药保健技术领域，具体涉及一种改善记忆的保健食品。
背景技术
记忆力下降是一种病症，临床上尤以40～60岁的知识女性最为多见，她们迫切渴望知识更新，却常常感到力不从心；一些中青年男性，由于社会压力引发心理问题，感到工作紧张、焦虑、易怒，导致记忆力下降。老年群体中的部分知识女性或退休人员，也主诉记忆受损，越是重要的东西比如说存折，总想放到一个稳妥的地方却常常找不到。目前缺少改善记忆的保健食品。
发明内容
发明目的：本发明提供了一种改善记忆的保健食品。
技术方案：一种改善记忆的保健食品，它由如下重量份数的原料制备得到：白芷20-30份、百合15-25份、佛手10-15份、茯苓10-25份、荷叶10-20份、火麻仁10-15份、玫瑰花5-10份。
所述改善记忆的保健食品，它由如下重量份数的原料制备得到：白芷25份、百合20份、佛手12份、茯苓18份、荷叶15份、火麻仁12份、玫瑰花8份。
所述所述改善记忆的保健食品，保健食品剂型为固体饮料。
所述改善记忆的保健食品，制备方法为：取上述原料，粉碎成细粉，分装，即得固体饮料。
有益效果：本发明具有改善记忆作用。
具体实施方式
以下通过实施例形式对本发明的上述内容再作进一步的详细说明，但不应将此理解为本发明上述主题的范围仅限于以下的实施例，凡基于本发明上述内容所实现的技术均属于本发明的范围。
实施例1：取白芷20份、百合25份、佛手10份、茯苓25份、荷叶10份、火麻仁15份、玫瑰花5份，制备方法为：取上述原料，粉碎成细粉，分装，即得固体饮料。
实施例2：取白芷30份、百合15份、佛手15份、茯苓10份、荷叶20份、火麻仁10份、玫瑰花10份，制备方法为：取上述原料，粉碎成细粉，分装，即得固体饮料。
实施例3：取白芷25份、百合20份、佛手12份、茯苓18份、荷叶15份、火麻仁12份、玫瑰花8份，制备方法为：取上述原料，粉碎成细粉，分装，即得固体饮料。
实施例4：实施例3本发明对老龄鼠认知障碍模型的影响实验
本发明药液的制备：取实施例3得本发明，加水浸泡，得本发明药液样品。
SPF级SD老龄大鼠，雄性，超过18月龄，体重450-500g。将老龄鼠用10％水合氯醛按350mg/kg的剂量经腹腔注射麻醉，颈部备皮并消毒后，沿颈部正中切开皮肤，钝性分离动脉鞘、迷走神经，暴露双侧颈总动脉，用4号手术线分别结扎双侧颈总动脉导致慢性脑缺血，造成认知功能障碍大鼠模型。将模型大鼠随机分为模型对照组、本发明高剂量组和中药低剂量组。另设正常对照组和假手术组(只分离双侧颈总动脉而不结扎，其余过程与手术相同)。术后24h，本发明高剂量组和低剂量组大鼠灌胃上述中药提取物药液，剂量分别为8mL/kg、4mL/kg；正常对照组、模型对照组和假手术组大鼠灌胃纯化水8mL/kg。各组每天灌胃1次，连续给予受试物2月。
给予受试物结束后，实验人员采用Morris水迷宫进行老龄鼠行为学测试。水迷宫为直径120cm，高60cm的圆形水池，水深30cm，在池壁上标4个入水点，将水池等分为4个象限，在第2象限正中池壁25cm处放一个直径为9.5cm，高28cm的圆形平台，平台低于水面2cm。水温保持在(25±2)℃。池壁、水及平台均被染黑且不透明，以至不能看见水下的平台。水迷宫测试的房间内保持安静，训练期间迷宫外的参照物保持不变，以测试老龄鼠的空间学习和记忆能力。每只老龄鼠每天进行4次训练，每次分别从每个象限的固定点作为入水点，连续训练5d。在训练结束后当天，观察并记录老龄鼠爬上平台所需的时间(潜伏期)。如果老龄鼠在120s内找到平台，记录老龄鼠找到平台的实际时间，即为潜伏期；如超过120s还未找到平台，则将潜伏期记为60s。每只老龄鼠的训练间隔为1h。在水迷宫实验的第6天撤掉平台，选择第1象限为入水点，观察并记录老龄鼠100s内在原平台所在的第2象限停留的时间。试验结果参见表1。
表1 各组老龄鼠逃避潜伏期和平台所在象限停留时间比较(s)
与模型对照组比较，★P＜0.05；与模型对照组比较，★★P＜0.01。
通过表1的试验结果可以看出，经连续5d的训练，模型对照组逃避潜伏期明显长于假手术组和正常对照组，而本发明高、低剂量组的逃避潜伏期均明显短于模型对照组(P＜0.01)。第6天拆掉平台后，模型对照组在原平台所在象限停留时间明显低于正常对照组和假手术组，而本发明高、低剂量组均明显高于模型对照组(P＜0.05或P＜0.01)。以上试验结果表明，本发明的保健食品可以改善认知障碍老龄鼠的空间学习能力。
显然，本发明的上述实施例仅仅是为清楚地说明本发明所作的举例，而并非是对本发明的实施方式的限定。对于所属领域的普通技术人员来说，在上述说明的基础上还可以做出其它不同形式的变化或变动。这里无需也无法对所有的实施方式予以穷举。而这些属于本发明的实质精神所引伸出的显而易见的变化或变动仍属于本发明的保护范围。
Claims (4)
1.一种改善记忆的保健食品，其特征在于，它由如下重量份数的原料制备得到：白芷20-30份、百合15-25份、佛手10-15份、茯苓10-25份、荷叶10-20份、火麻仁10-15份、玫瑰花5-10份。
2.如权利要求1所述改善记忆的保健食品，其特征在于，它由如下重量份数的原料制备得到：白芷25份、百合20份、佛手12份、茯苓18份、荷叶15份、火麻仁12份、玫瑰花8份。
3.如权利要求1所述改善记忆的保健食品，其特征在于，保健食品剂型为固体饮料。
4.如权利要求1所述改善记忆的保健食品，其特征在于，制备方法为：取上述原料，粉碎成细粉，分装，即得固体饮料。
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102198241A (zh) * | 2010-03-26 | 2011-09-28 | 王忠民 | 一种缓解紧张情绪与调理亚健康的药物 |
| CN104256613A (zh) * | 2014-10-11 | 2015-01-07 | 王�琦 | 一种改善气郁体质的食品及其制备工艺 |
| CN106035831A (zh) * | 2016-08-11 | 2016-10-26 | 亳州市益众堂保健食品有限公司 | 一种增强记忆力保健茶及其制作方法 |
| CN106174568A (zh) * | 2016-07-20 | 2016-12-07 | 柳州名品科技有限公司 | 一种辅助改善记忆的保健食品 |
| CN106473099A (zh) * | 2016-10-12 | 2017-03-08 | 钟术光 | 功效改善的功能性食品或代用茶 |
-
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- 2017-10-25 CN CN201711005579.0A patent/CN107889996A/zh not_active Withdrawn
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102198241A (zh) * | 2010-03-26 | 2011-09-28 | 王忠民 | 一种缓解紧张情绪与调理亚健康的药物 |
| CN104256613A (zh) * | 2014-10-11 | 2015-01-07 | 王�琦 | 一种改善气郁体质的食品及其制备工艺 |
| CN106174568A (zh) * | 2016-07-20 | 2016-12-07 | 柳州名品科技有限公司 | 一种辅助改善记忆的保健食品 |
| CN106035831A (zh) * | 2016-08-11 | 2016-10-26 | 亳州市益众堂保健食品有限公司 | 一种增强记忆力保健茶及其制作方法 |
| CN106473099A (zh) * | 2016-10-12 | 2017-03-08 | 钟术光 | 功效改善的功能性食品或代用茶 |
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