CN107881096A - The installation site adjustment structure of sequenator reagent platform - Google Patents
The installation site adjustment structure of sequenator reagent platform Download PDFInfo
- Publication number
- CN107881096A CN107881096A CN201610877777.5A CN201610877777A CN107881096A CN 107881096 A CN107881096 A CN 107881096A CN 201610877777 A CN201610877777 A CN 201610877777A CN 107881096 A CN107881096 A CN 107881096A
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- Prior art keywords
- platform
- reagent
- sequenator
- support panel
- bottom plate
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- 239000003153 chemical reaction reagent Substances 0.000 title claims abstract description 100
- 238000009434 installation Methods 0.000 title claims abstract description 30
- 239000007788 liquid Substances 0.000 claims description 4
- 239000007853 buffer solution Substances 0.000 claims description 3
- 239000002699 waste material Substances 0.000 claims description 3
- 238000002493 microarray Methods 0.000 abstract description 10
- 238000004806 packaging method and process Methods 0.000 abstract description 2
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 description 6
- 235000004443 Ricinus communis Nutrition 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000011900 installation process Methods 0.000 description 2
- 230000033001 locomotion Effects 0.000 description 2
- 238000012163 sequencing technique Methods 0.000 description 2
- BYACHAOCSIPLCM-UHFFFAOYSA-N 2-[2-[bis(2-hydroxyethyl)amino]ethyl-(2-hydroxyethyl)amino]ethanol Chemical group OCCN(CCO)CCN(CCO)CCO BYACHAOCSIPLCM-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003542 behavioural effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000000686 essence Substances 0.000 description 1
- 208000032839 leukemia Diseases 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
Abstract
The present invention relates to sequenator technical field, there is provided a kind of installation site adjustment structure of sequenator reagent platform, including sequenator bottom plate, platform support panel, stage+module plate and reagent platform；On stage+module plate, platform support panel is located at below reagent platform reagent stage+module, and is connected between reagent platform and platform support panel by multiple support columns；Platform support panel has the first drift angle and the second drift angle on same diagonal, and sequenator bottom plate has the first corner；Platform support panel is fixed on sequenator bottom plate, and the first drift angle of wherein platform support panel is fixed on the first corner of sequenator bottom plate, and the second drift angle of platform support panel is located in sequenator bottom plate；Second vertex of platform support panel is provided with the first adjusting means；The beneficial effects of the invention are as follows：The installation difficulty of reagent platform is reduced, improves the packaging efficiency of microarray dataset.
Description
Technical field
The present invention relates to sequenator technical field, more particularly, it relates to a kind of peace of sequenator reagent platform
Holding position adjusts structure.
Background technology
Gene sequencing is a kind of novel gene detection technique, can analyze measure gene complete sequence, and a variety of diseases are suffered from prediction
The possibility of disease, individual behavioural characteristic and behavior are reasonable, such as cancer or leukaemia, motion talent, capacity for liquor etc..
Gene sequencer of the prior art, typically all including main body frame, main body frame includes the bottom plate positioned at bottom,
Multiple modules, such as reagent console module, Z axis liquid relief module etc. are provided with described main body frame.Wherein reagent is put down
Platform module is when mounted, it is necessary to the bottom of reagent console module is fixed on bottom plate, while by the reagent of reagent console module
Stage+module is on stage+module plate.
Because gene sequencer total quality is larger, before the module installation in by main body frame, need to be installed on bottom plate
Castor, in order to the movement of gene sequencer.After installing castor, due to not installing modules also on bottom plate, bottom plate can produce
Certain deformation, now such as the bottom of reagent console module is fixed on bottom plate, the reagent platform of reagent console module then with
Stage+module plate can not fit like a glove, and cause the installation difficulty of reagent platform, it is necessary to reset bottom plate by external force, can
Reagent platform is fixed on stage+module plate so that the overall installation process of sequenator is very cumbersome, the installation effectiveness of sequenator
Lowly.
Therefore need a kind of installation site of sequenator reagent platform to adjust structure, reagent platform can be adjusted,
So that reagent platform coincide with stage+module plate, the installation difficulty of sequenator is reduced.
The content of the invention
It is an object of the invention to provide a kind of installation site of sequenator reagent platform to adjust structure, it is intended to solves existing
The problem of overall installation process of technology sequence instrument is very cumbersome, and the installation effectiveness of sequenator is low.
In order to realize goal of the invention, a kind of installation site adjustment structure of sequenator reagent platform, it is theed improvement is that：
Including sequenator bottom plate, platform support panel, stage+module plate and reagent platform；The reagent stage+module is in described platform
On installing plate, described platform support panel is located at below reagent platform, and by multiple between reagent platform and platform support panel
Support column connects；
The platform support panel has the first drift angle and the second drift angle on same diagonal, and the sequenator bottom plate has
First corner；The platform support panel is fixed on described sequenator bottom plate, and the first drift angle of wherein platform support panel is fixed
In the first corner of the sequenator bottom plate, the second drift angle of the platform support panel is located in described sequenator bottom plate；
Second vertex of the platform support panel is provided with the first adjusting means, and first adjusting means is used to adjust platform branch
Second drift angle of fagging and the spacing of sequenator bottom plate, so as to adjust coincideing between the reagent platform and stage+module plate
Degree.
In such a configuration, the platform support panel is square, and has perpendicular first side and second side, and
The intersection of first side and second side is the second described drift angle；
It is provided with the second adjusting means on the platform support panel, and second adjusting means is close to the first described side
Side；
It is additionally provided with the 3rd adjusting means on the platform support panel, and the 3rd adjusting means is close to the second described side
Side.
Further, the platform support panel also has the 3rd perpendicular side and a four side, and the 3rd side with
The intersection of four side is the first described drift angle；
The first side and the intersection of four side are the 3rd drift angle, and the second described adjusting means is located at the 3rd drift angle
Place.
Further, the structure of first adjusting means, the second adjusting means and the 3rd adjusting means is identical, wraps
Adjusting nut and adjusting screw are included, the adjusting nut is enclosed in adjusting screw, and screwed hole is provided with the platform support panel,
The adjusting screw passes through to be pressed on described sequenator bottom plate in described screwed hole, the top of adjusting screw.
In such a configuration, the support column is provided with the first positioning hole, the reagent platform up and down on end surfaces
Lower surface and platform support panel upper surface corresponding to be provided with the second positioning hole, set in the first positioning hole and the second positioning hole
It is equipped with alignment pin.
Further, the upper and lower side of the support column stretches out to form a protuberance respectively, and is provided with protuberance
Fixed screw holes are provided with corresponding to through hole, the lower surface of the reagent platform and the upper surface of platform support panel.
In such a configuration, in addition to back side panel, after the back side panel is arranged on platform support panel and reagent platform
Portion, the reagent platform and platform support panel are vertically fixed on described back side panel.
In such a configuration, multiple reagents are provided with the reagent platform and place position, the reagent, which places position, to be included
Reagent delivery device places position, buffer solution places position, orifice plate places position and waste liquid places position.
Further, circulating fan is installed on the platform support panel.
From the foregoing, it will be observed that the first corner of the invention by the way that the first drift angle of platform support panel to be attached to sequenator bottom plate
Place, because the second vertex is provided with adjusting means, causes reagent platform and stage+module plate when sequenator bottom plate deforms upon
Through hole when can not coincide, by the adjustment effect of adjusting means, the spacing of the second drift angle and sequenator bottom plate can be adjusted, from
And inclined reagent platform is in horizontality, now reagent platform can then be kissed completely between the through hole of stage+module plate
Close, so as to complete the fixation of reagent platform；This mode reduces the installation difficulty of reagent platform, improves the group of microarray dataset
Fill efficiency.
Brief description of the drawings
Fig. 1 is the structural representation of microarray dataset in one embodiment of the invention.
Fig. 2 is that the installation site of sequenator reagent platform in one embodiment of the invention adjusts the structural representation of structure.
Fig. 3 is that the installation site of sequenator reagent platform in one embodiment of the invention adjusts principle schematic diagram.
Fig. 4 is the overlooking the structure diagram of platform support panel in one embodiment of the invention.
Fig. 5 is diagrammatic cross-section at A-A in Fig. 4.
Fig. 6 is the partial enlarged drawing at B in Fig. 5.
Fig. 7 is the structural representation of support column in one embodiment of the invention.
Fig. 8 is that the installation site of sequenator reagent platform in another embodiment of the present invention adjusts the structural representation of structure
Figure.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, it is right below in conjunction with drawings and Examples
The present invention is further elaborated.
The present invention proposes first embodiment, and the present embodiment proposes a kind of installation site adjustment knot of sequenator reagent platform
Structure, as shown in Figure 1 and Figure 2, the microarray dataset supporting plate installation and adjustment structure include microarray dataset 10, and the bottom of microarray dataset 10 is set
Supporting leg 101 is equipped with, 101 can be provided with castor on the supporting leg（Not shown in figure）, in order to which microarray dataset 10 is moved
It is dynamic.Stage+module plate 20 is provided with microarray dataset 10, reagent platform 30 is then arranged on stage+module plate 20；Certainly, it is necessary to
Illustrate that also there are other modules in the microarray dataset 10, such as power module etc., Fig. 1, Fig. 2 in the present embodiment
In do not identify other modules.
As shown in Fig. 2 also including sequenator bottom plate 40 and platform support panel 50, multiple reagents are provided with reagent platform 30
Position 301 is placed, the reagent is placed position 301 and will be hereinafter described in detail.Reagent platform 30 is arranged on described platform
On installing plate 20, in general, the through hole for accommodating the reagent platform 30, the shape of through hole are reserved with stage+module plate 20
Shape is identical with the size of reagent platform 30, so as to be fixed on reagent platform 30 in the through hole of stage+module plate 20.Described is flat
Platform supporting plate 50 is located at the lower section of reagent platform 30, and passes through multiple support columns 60 between reagent platform 30 and platform support panel 50
It is connected.
As shown in figure 3, described platform support panel 50 has the first drift angle 501 and the second top on same diagonal
Angle 502, described sequenator bottom plate 40 have the first corner 401；Platform support panel 50 is fixed on described sequenator bottom plate 40
On, and the first drift angle 501 of the platform support panel 50 is fixed at the first corner 401 of the sequenator bottom plate 40, institute
The second drift angle 502 of platform support panel 50 is stated then positioned at the described middle part of sequenator bottom plate 40；As shown in Figure 2 and Figure 3, it is described flat
The first adjusting means 70 is provided with second drift angle 502 of platform supporting plate 50, first adjusting means 70 is used to adjust platform branch
The spacing of fagging 50 and sequenator bottom plate 40, so as to adjust the goodness of fit between the reagent platform 30 and stage+module plate 20.
In the fixation procedure of reagent platform 30 and platform support panel 50, because the area of sequenator bottom plate 40 is larger, sequencing
After the Four built in boundaries of instrument bottom plate 40, small deformation occurs in the middle part of sequenator bottom plate 40, and platform support panel 50 is fixed on
After on sequenator bottom plate 40, inclination then occurs in reagent platform 30, and reagent platform 30 can not be with leading on stage+module plate 20
Hole is matched, it is difficult to which reagent platform 30 is fixed.In the present embodiment, the first drift angle 501 of platform support panel 50 is installed
To the first corner 401 of sequenator bottom plate 40, due to being provided with the first adjusting means 70 at the second drift angle 502, work as sequenator
Bottom plate 40 is deformed upon when causing the through hole of reagent platform 30 and stage+module plate 20 not coincide, and passes through the first adjusting means 70
Adjustment effect, the spacing of the second drift angle 502 and sequenator bottom plate 40 can be adjusted, so as to be carried out to the position of reagent platform 30
Adjustment, now described reagent platform 30 can then fit like a glove between the through hole of stage+module plate 20, so as to complete reagent
The fixation of platform 30；This mode reduces the installation difficulty of reagent platform 30, improves the packaging efficiency of microarray dataset.
Further, as shown in figure 3, on the basis of above-described embodiment, the invention also provides an embodiment, this implementation
In example, structure that described platform support panel 50 is square has perpendicular a first side 503 and second side 504, and first
The intersection of side 503 and second side 504 is the second described drift angle 502；Is provided with the platform support panel 50
Two adjusting meanss 80 and the 3rd adjusting means 90, wherein the second adjusting means 80 is adjusted close to described first side 503, the 3rd
Regulating device 90 is close to described second side 504.Preferably, the platform support panel 50 also has the 3rd perpendicular side
505 and four side 506, and the 3rd side 505 and the intersection of four side 506 are the first described drift angle 501；It is described
First side 503 and the intersection of four side 506 are the 3rd drift angle 507, and the second described adjusting means 80 is positioned at the 3rd top
At angle 507.Pass through the design of this structure, the first adjusting means 70, the second adjusting means 80 and the structure of the 3rd adjusting means 90
Into a triangle, during the regulation to reagent platform 30, it is applied to by three points on platform support panel 50 so that right
It is more accurate in the regulation of the second drift angle 502 of platform support panel 50, so that the kiss of reagent platform 30 and stage+module plate 20
It is right higher, further reduce the installation difficulty of reagent platform 30.
In above-mentioned any embodiment, for the first described adjusting means 70, the second adjusting means 80 and the 3rd
Adjusting means 90, the present invention propose a specific embodiment, the first described adjusting means 70, the second adjusting means 80 and
The structure of three adjusting meanss 90 is identical, therefore is only illustrated in the present embodiment by taking the first adjusting means 70 as an example.Such as Fig. 4 institutes
Show, be the overlooking structure figure of platform support panel 50, Fig. 5 is that diagrammatic cross-section, Fig. 6 are the office at B in Fig. 5 at A-A in Fig. 4
Portion's enlarged drawing, the first adjusting means 70 include adjusting nut 701 and adjusting screw 702, and the adjusting nut 701 is enclosed on regulation spiral shell
On nail 702, corresponding screwed hole is provided with the platform support panel 50, the adjusting screw 702 is passed through in described screw thread
Hole, the top of adjusting screw 702 are pressed on described sequenator bottom plate 40.When needing regulation, unscrew described regulation first
Nut 701, described adjusting screw 702 is rotated, adjusting screw 702 rotates in the screwed hole of sequenator bottom plate 40, so as to adjust
Save the spacing of the second drift angle 502 and sequenator bottom plate 40 of platform support panel 50；After the completion of regulation, described adjusting nut is tightened
701 can the good position of stable regulation.
For above-mentioned support column 60, as shown in fig. 7, the present invention proposes a specific embodiment, the support column 60
The first positioning hole 601, the lower surface of the reagent platform 30 and the upper surface of platform support panel 50 are provided with upper and lower end surfaces
It is corresponding to be provided with the second positioning hole 508, alignment pin 602 is provided with the first positioning hole 601 and the second positioning hole 508, is led to
Cross alignment pin 602 and positioning action is played to support column 60；Further, the upper and lower side of the support column 60 stretches out respectively
A protuberance is formed, and through hole is provided with protuberance, the lower surface of the reagent platform 30 and the upper table of platform support panel 50
Fixed screw holes 509 are provided with corresponding to face, by locking fixed screw 603, so as to which the upper end of support column 60 is fixed on into examination
The lower surface of agent platform 30, the lower end of support column 60 is fixed on to the upper surface of platform support panel 50.
In above-mentioned any embodiment, as shown in figure 8, the installation site adjustment structure of sequenator reagent platform also includes
Back side panel 100, the back side panel 100 are arranged on the rear portion of platform support panel 50 and reagent platform 30, the He of reagent platform 30
Platform support panel 50 is vertically fixed on described back side panel.In the present embodiment, reagent is provided with the reagent platform 30
Transmitting device 200, described reagent, which places position, includes buffer solution placement position 302, orifice plate placement position 303 and waste liquid placement position
304, and circulating fan 305 is installed on the platform support panel 50, circulating fan 305 is arranged on a fan installing plate 306
On, the circulation of wind direction in sequenator is realized by the effect of circulating fan 305.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
All any modification, equivalent and improvement made within refreshing and principle etc., should be included in the scope of the protection.
Claims (9)
- A kind of 1. installation site adjustment structure of sequenator reagent platform, it is characterised in that：Including sequenator bottom plate, platform Plate, stage+module plate and reagent platform；The reagent stage+module is on described stage+module plate, described platform Plate is located at below reagent platform, and is connected between reagent platform and platform support panel by multiple support columns；The platform support panel has the first drift angle and the second drift angle on same diagonal, and the sequenator bottom plate has First corner；The platform support panel is fixed on described sequenator bottom plate, and the first drift angle of wherein platform support panel is fixed In the first corner of the sequenator bottom plate, the second drift angle of the platform support panel is located in described sequenator bottom plate Portion；Second vertex of the platform support panel is provided with the first adjusting means, and first adjusting means is used to adjust platform branch Second drift angle of fagging and the spacing of sequenator bottom plate, so as to adjust coincideing between the reagent platform and stage+module plate Degree.
- 2. the installation site adjustment structure of sequenator reagent platform according to claim 1, it is characterised in that：The platform Supporting plate is square, and has perpendicular first side and second side, and the intersection of first side and second side is The second described drift angle；It is provided with the second adjusting means on the platform support panel, and second adjusting means is close to the first described side Side；It is additionally provided with the 3rd adjusting means on the platform support panel, and the 3rd adjusting means is close to the second described side Side.
- 3. the installation site adjustment structure of sequenator reagent platform according to claim 2, it is characterised in that：The platform Supporting plate also has the 3rd perpendicular side and four side, and the 3rd side and the intersection of four side are described First drift angle；The first side and the intersection of four side are the 3rd drift angle, and the second described adjusting means is located at the 3rd drift angle Place.
- 4. the installation site adjustment structure of sequenator reagent platform according to claim 2, it is characterised in that：Described first The structure of adjusting means, the second adjusting means and the 3rd adjusting means is identical, described including adjusting nut and adjusting screw Adjusting nut is enclosed in adjusting screw, and screwed hole is provided with the platform support panel, and the adjusting screw is passed through in described Screwed hole, the top of adjusting screw are pressed on described sequenator bottom plate.
- 5. the installation site adjustment structure of sequenator reagent platform according to claim 1, it is characterised in that：The support Post is provided with the first positioning hole up and down on end surfaces, the lower surface of the reagent platform and the upper surface of platform support panel are corresponding Be provided with the second positioning hole, be provided with alignment pin in the first positioning hole and the second positioning hole.
- 6. the installation site adjustment structure of sequenator reagent platform according to claim 5, it is characterised in that：The support The upper and lower side of post stretches out to form a protuberance respectively, and through hole is provided with protuberance, the lower surface of the reagent platform With the upper surface of platform support panel corresponding to be provided with fixed screw holes, by locking screw into through hole and fixed screw holes, The reagent platform and platform support panel are separately fixed to the upper and lower side of support column.
- 7. the installation site adjustment structure of sequenator reagent platform according to claim 1, it is characterised in that：After also including Side plate, the back side panel are arranged on the rear portion of platform support panel and reagent platform, and the reagent platform and platform support panel hang down It is straight to be fixed on described back side panel.
- 8. the installation site adjustment structure of sequenator reagent platform according to claim 1, it is characterised in that：The reagent Multiple reagents are provided with platform and place position, the reagent placement position includes reagent delivery device placement position, buffer solution places position, Orifice plate places position and waste liquid places position.
- 9. the installation site adjustment structure of sequenator reagent platform according to claim 8, it is characterised in that：The platform Circulating fan is installed in supporting plate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610877777.5A CN107881096A (en) | 2016-09-30 | 2016-09-30 | The installation site adjustment structure of sequenator reagent platform |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610877777.5A CN107881096A (en) | 2016-09-30 | 2016-09-30 | The installation site adjustment structure of sequenator reagent platform |
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| CN107881096A true CN107881096A (en) | 2018-04-06 |
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| CN201610877777.5A Pending CN107881096A (en) | 2016-09-30 | 2016-09-30 | The installation site adjustment structure of sequenator reagent platform |
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