CN107854114A - Passive drive rotation sweep optic probe - Google Patents

Passive drive rotation sweep optic probe Download PDF

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Publication number
CN107854114A
CN107854114A CN201710948116.1A CN201710948116A CN107854114A CN 107854114 A CN107854114 A CN 107854114A CN 201710948116 A CN201710948116 A CN 201710948116A CN 107854114 A CN107854114 A CN 107854114A
Authority
CN
China
Prior art keywords
inner sleeve
propeller
outer tube
reflecting element
optical fiber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201710948116.1A
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Chinese (zh)
Other versions
CN107854114B (en
Inventor
卢宇
李中梁
王向朝
南楠
陈艳
王瑄
潘柳华
宋思雨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Institute of Optics and Fine Mechanics of CAS
Original Assignee
Shanghai Institute of Optics and Fine Mechanics of CAS
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Priority to CN201710948116.1A priority Critical patent/CN107854114B/en
Publication of CN107854114A publication Critical patent/CN107854114A/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • A61B5/0066Optical coherence imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163Optical arrangements
    • A61B1/00165Optical arrangements with light-conductive means, e.g. fibre optics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163Optical arrangements
    • A61B1/00172Optical arrangements with means for scanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163Optical arrangements
    • A61B1/00188Optical arrangements with focusing or zooming features
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters

Abstract

A kind of passive drive rotation sweep optic probe, including the device such as inner sleeve, optical fiber, outer tube, light focusing element, propeller, rotatable parts, reflecting element;Propeller is fixedly installed on rotatable parts, and reflecting element is fixed on the center of propeller insertion rotatable parts one end rotating shaft.Reflecting element, propeller, rotatable parts are together installed on the end of inner sleeve.When liquid such as injecting normal salines, liquid, which washes away propeller, makes propeller rotational, so as to drive the reflecting element installed in propeller rotating shaft to rotate.From the laser light incident that is emitted after light focusing element focusing to the reflecting surface of reflecting element, sample is then reflexed to, laser can carry out 360 degree of shadow-frees to sample and scan when reflecting element rotates.The transmission optical signalling that the present invention can stablize, have the advantages that without external power driving scans, safe, stability is high, no-raster shadow region, can radial direction 360 degree of scannings, influenceed by non-uniform rotational distortion it is small.

Description

Passive drive rotation sweep optic probe
Technical field
The present invention relates to medical imaging instruments, particularly a kind of optic probe available for based endoscopic imaging.
Background technology
Optical coherent chromatographic imaging (Optical Coherence Tomography, OCT) is that one kind utilizes weak coherent light The advanced imaging technique of interferometer principle, is widely used in medical field.The technology peeps biomedical when detecting pairs in progress Optic probe proposes strict demand, and probe size is as small as possible, to stablize in the course of work, can carry out 360 degree of scannings Deng.Have Duo Jia scientific research institutions both at home and abroad at present and carried out correlative study for the OCT optic probes for based endoscopic imaging.
First technology one discloses one kind (referring to the patent of invention document that China Patent Publication No. is CN104887172A) For the novel non radiation OCT probe and measuring system of blood vessel detection, the motor for driving whole probe rotation is placed in by the probe The distal end of optic probe, the torque wire that installation is made with spring in probe, when machine shaft rotates, driven by linkage Whole optic probe rotates together.The technical scheme can carry out 360 degree of unobstructed imaging to cavity inwall, but the technical side Case rotates due to needing to transmit moment of torsion by torque wire and drive to pop one's head in, and causes probe velocity of rotation to be restricted;It is remote to be placed in probe The motor volume at end is larger, causes whole probe size larger, is unfavorable for using;And due to cavity often it is irregular, Bending, non-uniform rotational distortion be present into image so as to cause, influence OCT system imaging quality.
First technology two discloses one kind (referring to the patent of invention document that China Patent Publication No. is CN102401995B) Endoscope miniature optical probe, by micro electro mechanical system (MEMS) technology (micro-electromechanical system, abbreviation MEMS) Scanning micro-mirror be arranged on OCT optic probes end, by applying voltage and current to MEMS scanning micro-mirror, make its radial direction or Front and rear vibration, so as to which the light for inciding its surface to be reflexed to the different zones of organization internal to complete to sweep object to be detected Retouch.Radially vibration angle is limited due to scanning micro-mirror for the optic probe, and needs its side window during using the probe It is aligned with sample and carries out optical scanner, so can only be scanned to a part for cavity side wall, to be carried out to cavity side wall 360 degree of scannings are not easy to use, its application is extremely restricted, it is necessary to can be manually rotated the probe.
First technology three discloses one kind (referring to the patent of invention document that China Patent Publication No. is CN202437064U) OCT electronic gastroscope systems, the probe of the system are the optic probe using micromachine, and reflecting element is arranged on micro- by it On type motor, reflecting element reflecting surface with light focusing element install by the face in probe, and motor wire is close to outside probe from afterbody Internal surface of sleeve pipe passes through gap between reflecting element and light focusing element to send feeder ear back to.Machine shaft drives anti-on its axle after rotating Element rotation is penetrated, the light that reflecting element reflecting surface is incided by light focusing element is reflexed on cavity wall, so as to cavity wall It is scanned.The technical scheme can carry out 360 degree of scannings to cavity side wall.But the shortcomings that this structure is due to that motor is led Line, by outer sleeve inner wall wraparound, causes that during scanning a part of cavity side wall can be blocked, so as to cause OCT systems to chamber from afterbody Road imaging is imperfect.
In above-mentioned formerly technical scheme, the rotary part of probe is required to external power source and provides power, belongs to active matrix driving. And formerly the rotary part in technology two, three is placed in probe end, current supply line need to enter human body, driving end component scan or Rotation.In Clinical practice, if probe rupture, can cause human electric shock.Therefore, the active drive of electric power is provided outside this kind of needs The dynamic probe risk certain to human life security presence in Clinical practice.
The content of the invention
The shortcomings that for above-mentioned prior art, the present invention provide a kind of passive drive rotation sweep optic probe.The present invention Probe end is provided with rotatable parts and propeller, and spiral is converted into using the kinetic energy of the liquid during liquid such as injecting normal saline The rotational kinetic energy of oar, liquid wash away propeller and drive propeller rotational, drive propeller to be installed on rotatable parts one end Reflecting element rotate, and then realize scanning to vascular wall.The optic probe can stably transmit optical signalling, have nothing Need external power drive scan, be safe, stability is high, no-raster shadow region, can radial direction 360 degree of scannings, without non-homogeneous The characteristics of rotational distortion.
The technical solution of the present invention is as follows:
A kind of passive drive rotation sweep optic probe, its feature are:It is focused on by inner sleeve, optical fiber, outer tube, light Element, propeller, rotatable parts and reflecting element composition;
The center of described inner sleeve is the top and fibre-optical splice phase of described optical fiber, described inner sleeve and optical fiber Even, the fibre-optical splice is used to connect light source, the described outer tube of the end insertion of described inner sleeve and optical fiber and along described Outer tube advances, and described inner sleeve is coaxial with described outer tube and has the gap flowed for liquid between the two, and described is interior The intersection of the described outer tube of sleeve pipe insertion is sealing, and the light that the end connection of the optical fiber of described inner sleeve is described focuses on Element, several millimeters of the end of the described outer tube of light focusing element stretching, described reflecting element, rotatable parts, propeller It is permanently connected together and is arranged on described fiber-coaxial outside the end of described inner sleeve, described overcoat successively There is connector at the top of pipe, and the connector is connected with fluid infusion apparatus, and the light described from the light beam warp of fiber exit focuses on member After part focuses on, on the reflecting surface that incides described reflecting element;
When described fluid infusion apparatus injects liquid into described outer tube, the liquid can be from described inner sleeve The end in the space between outer tube is emitted and washes away described propeller, drives described rotatable parts and light reflection element Rotate together, realize scanning of the light beam to testing sample.
The end of described inner sleeve is provided with mat.
Described light focusing element both ends of the surface are polished into oblique 8 degree of angles.
Described light focusing element is coated with anti-reflection film in both ends of the surface.
Described reflecting element is coated with reflectance coating in reflecting surface.
The reflecting element is fixed on the centre of rotating shaft one end of the described rotatable parts of described propeller insertion.
The overall diameter of diameter and rotatable parts in described inner sleeve is equal or slightly less than rotatable parts overall diameter, rotates Part is fixedly mounted in the end of described inner sleeve with glue or bayonet unit, installs back reflection element and rotatable parts In interior inside pipe casing, the paddle section of described propeller is in the exterior end of described inner sleeve, and rotatable parts and inner sleeve It is concentric to manage concentric, described propeller, rotatable parts, inner sleeve, reflecting element.
Described light focusing element is fixedly mounted in described inner sleeve, with being fixedly mounted in described inner sleeve Optical fiber connector it is concentric and be adhered to optical fiber connector with optical glue, or have a slight gap with optical fiber connector, and with reflection There is slight gap between element.
The same optical axis of the optical fiber, light focusing element, propeller, rotatable parts, reflecting element, ensures the light from fiber exit Into after light focusing element, after appropriate focusing, hot spot can incide on the reflecting surface of reflecting element completely.
The inner sleeve passes through outer tube, and the end through part is the one end for being provided with rotatable parts, propeller. There are several limit elements the end to ensure that inner sleeve and outer tube are concentric and there have between the two to be appropriate at outer tube Gap.Several millimeters described of outer tube is stretched out in the end of inner sleeve.
The intersection glue sealing adhesion of the inner sleeve insertion outer tube, ensures that liquid will not ooze when flowing through at this Leakage;
When carrying out optical coherent chromatographic imaging to vascular wall using the present invention, physiological saline and so on liquid is injected with liquid and filled Put from outer tube and inject, these liquid are flowed to intravascular with certain speed by the gap of inner sleeve and outer tube.In inner sleeve End, propeller is rotated by the impact of liquid, so as to drive the reflecting element that is installed on propeller shaft to rotate.Gather from light The laser light incident of burnt element outgoing after reflection penetrates inner sleeve tube wall, is incided on vascular wall to after reflecting element reflecting surface. When reflecting element rotates, laser can carry out 360 degree of shadow-free scannings to vascular wall.
Preferably, the inner sleeve pipe end is provided with mat, for protecting propeller to avoid it from being connect with testing sample Touch.
Preferably, the light focusing element is coated with anti-reflection film in both ends of the surface, to reduce return loss.
Preferably, the reflecting element is coated with reflectance coating in reflecting surface, incident to increase the light of light focusing element outgoing To reflectivity during reflecting element reflecting surface.
Compared with prior art, the beneficial effects of the invention are as follows:
1) probe rotation sweep is driven without external power source, is passive device, have human body when being ruptured in the absence of probe tactile The risk of electricity;
2) in addition, three major defects of prior art are non-uniform rotational distortion be present, or can not be to cavity inwall 360 degree of scannings are carried out, or scanning shadow region be present.Compared with first technology one, the present invention is without using at fibre-optical splice end Torque wire is driven to transmit torque rotate probe using external motor, so as to abnormal in the absence of the non-homogeneous rotation thus brought Become;And compared with first technology two, the present invention can not carry out 360 without MEMS micromirror is used, so as to avoid to cavity inwall The shortcomings that degree scanning;Compared with first technology three, there is no wire in inner sleeve of the present invention, so as to avoid caused by wire blocks Scan shadow region.The present invention is simple to operate, stable performance in the course of work, and 360 degree of shadow-free scannings can be realized to cavity inwall.
Brief description of the drawings
Fig. 1 is reflecting element of the present invention, rotatable parts, propeller dimensional structure diagram;
Fig. 2 is reflecting element of the present invention, rotatable parts, propeller partial front view;
Fig. 3 is reflecting element of the present invention, rotatable parts, propeller top partial view diagram;
Fig. 4 is reflecting element of the present invention, rotatable parts, propeller part right view;
Fig. 5 is schematic structural view of the invention.
In figure:
1-1:Reflecting element;1-2:Rotatable parts;1-3:Propeller;2-1:Fibre-optical splice;2-2:Inner sleeve;2-3:Light It is fine; 2-4:Spacing ring;2-5:Light focusing element;2-6:Limit element;2-7:Mat;3-1:Overcoat pipe connector;3-2: Outer tube.
Embodiment
With reference to embodiment and accompanying drawing, the invention will be further described, but should not limit the present invention's with this embodiment Protection domain.
As shown in 5 figures, as seen from the figure, passive drive rotation sweep optic probe of the present invention, including it is fixedly installed in inner sleeve Optical fiber 2-3 in pipe 2-2, with optical fiber 2-3 end adhesions or the light focusing element 2-5 separated, reflecting element 1-1, rotatable parts The devices such as 1-2, propeller 1-3, outer tube 3-2.Described light focusing element 2-5 is fixedly mounted on inner sleeve with spacing ring 2-4 In 2-2, with optical fiber 2-3 axis coincidings, the light ensured from optical fiber connector outgoing, which enters after light focusing element 2-5, can obtain just Work as focusing.The spacing ring can use stainless steel or plastic production, can be glued between spacing ring and light focusing element, inner sleeve with glue Fixed is determined.
, can be in optical fiber and inner sleeve in order to ensure that optical fiber 2-3 is fixedly installed in inner sleeve 2-3 and both axis coincidings Between filled plastics foam or flexiplast, such inner sleeve can bend with optical fiber, be not easily broken.Optical fiber 2-3 is remote Propeller one end is provided with fibre-optical splice 2-1, and the fibre-optical splice can be FC/APC joints, for being connected with OCT light source, transmission Optical signal.
Optical fiber 2-3 and light focusing element 2-5 close to both one end can it is inter-adhesive with optical glue or have it is small between Every.
After propeller 1-3 rotating shaft insertion rotatable parts 1-2, both fixations, rotatable parts are inserted in propeller 1-3 The centre of 1-2 one end rotating shaft glue adhesion reflecting element 1-1.Then by rotatable parts 1-2, reflecting element 1-1 insertion Sleeve pipe 2-2 ends, inner sleeve 2-2 interior diameter and rotatable parts 1-2 overall diameters are equal or slightly less than straight outside rotatable parts 1-2 Footpath, rotatable parts 1-2 is fixedly installed in inner sleeve 2-2 end with glue, and rotatable parts 1-2 and inner sleeve 2-2 are coaxial The heart, i.e. propeller 1-3, rotatable parts 1-2, inner sleeve 2-2, light focusing element 2-5, optical fiber 2-3 are concentric.Reflection after fixation There is slight gap between element 1-1 and light focusing element 2-5.
Mat 2-7 is made by some finer wires, after it covers propeller 1-3 completely, its mouth Steel wire may be inserted into inner sleeve 2-2 ends or be fixed on inner sleeve 2-2 outer walls with glue adhesion, but be no more than reflecting element, keep away Exempt to stop the light beam reflected through reflecting element.
Inner sleeve 2-2 partially passes through outer tube 3-2, through part end close to outer tube 3-2 ends have 1 or Several limit elements 2-6, fixed with outer tube 3-2 inwalls and inner sleeve 2-2 outer wall adhesions, to ensure inner sleeve 2-2 with Outer tube 3-2 is concentric.Outer tube 3-2 ends are stretched out several millimeters in inner sleeve 2-2 ends.
There is the fluid infusion apparatus joint 3-1 being connected with fluid infusion apparatus outer tube 3-2 one end, for being noted with liquid Enter device in succession, allow physiological saline and so on liquid to enter outer tube during use.
In the selection of outer tube 3-2 and inner sleeve 2-2 material, transparent plastic FEP, PTFE, PC etc. can be selected.FEP is managed Chinese perfluoroethylene-propylene pipe, there is wider temperature in use, good saturating infrared optical property, toughness is high, and has Biological tissue's compatibility, nontoxic, easy-formation.Inner sleeve 2-2 thickness is smaller than 200um, to obtain higher light transmission rate.
In propeller 1-3 material selection, the materials such as photosensitive resin, 304 stainless steels can be selected.Due to propeller 1-3 Very little, stock size can select to be formed using 3D printing technique printing with photosensitive resin material, at present business in several millimeters The 3D printing technique precision of industry meets demand of the present invention in 0.1mm.
Reflecting element 1-1 can select reflecting surface to be coated with the right-angle prism of reflectance coating;Rotatable parts 1-2 can select diameter Less bearing.
The commercial minimum 125um of light focusing element 2-5 diameters is currently known, is adapted for mount in inner sleeve 2-2.Light focuses on Element 2-5 has self-focusing characteristic, selects the light focusing element 2-5 of appropriate length and can obtain suitable focus on light beam, makes to gather The spot diameter that defocused laser beam is incided on reflecting element 1-1 is less than reflecting element 1-1 reflecting surface size.
When the physiological saline and so on liquid being emitted from fluid infusion apparatus flows through outer tube 3-2 and washes away propeller 1-3, spiral shell Rotation oar 1-3 will start to rotate, so as to drive reflecting element 1-1 to rotate, so that the light through reflecting element 1-1 reflective surfaces Do 360 degree of circular scannings.360 degree of radial scans to vascular wall or its hetero-organization can be realized using the optic probe, are solved Torque is transmitted using torque wire and drives probe rotational band come non-uniform rotational distortion problem, while is solved using MEMS micromirror Optic probe radial scan region is small and optic probe using micromachine in imaging shadow problem caused by wire.
Experiment shows that passive drive rotation sweep optic probe of the present invention, when liquid such as injecting normal salines, liquid rushes Brush propeller makes propeller rotational, so as to drive the reflecting element installed in propeller rotating shaft to rotate.Focused on from light focusing element Then the laser light incident being emitted afterwards reflexes to sample, the laser when reflecting element rotates on the reflecting surface of reflecting element 360 degree of shadow-free scannings can be carried out to sample.The transmission optical signalling that the present invention can stablize, has without external electrical Power driving scanning, safe, stability is high, no-raster shadow region, can radial direction 360 degree of scannings, by non-uniform rotational distortion shadow Ring the advantages that small.

Claims (5)

  1. A kind of 1. passive drive rotation sweep optic probe, it is characterised in that:It is by inner sleeve (2-2), optical fiber (2-3), overcoat Manage (3-2), light focusing element (2-5), propeller (1-3), rotatable parts (1-2) and reflecting element (1-1) composition;
    The center of described inner sleeve (2-2) is the beginning of described optical fiber (2-3), described inner sleeve (2-2) and optical fiber (2-3) End is connected with fibre-optical splice (2-1), and the fibre-optical splice (2-1) is used to connect light source, described inner sleeve (2-2) and optical fiber (2- 3) end is inserted described outer tube (3-2) and advanced along described outer tube (3-2), described inner sleeve (2-2) and institute The outer tube (3-2) stated is coaxial and has the gap flowed for liquid between the two, the described overcoat of described inner sleeve (2-2) insertion The intersection of pipe (3-2) is sealing, and the light that the end connection of the optical fiber (2-3) of described inner sleeve (2-2) is described focuses on member Part (2-5), several millimeters of the end of the described outer tube (3-2) of the light focusing element (2-5) stretching, described reflecting element (1- 1), rotatable parts (1-2), propeller (1-3) are permanently connected together and are coaxially disposed with described optical fiber (2-3) successively Outside the end of described inner sleeve (2-2), there are connector (3-1), the connector (3- in the top of described outer tube (3-2) 1) it is connected with fluid infusion apparatus, it is incident from the light beam that optical fiber (2-3) is emitted after described light focusing element (2-5) focuses on Onto the reflecting surface of described reflecting element (1-1);
    When described fluid infusion apparatus injection liquid into described outer tube (3-2), the liquid can be from described inner sleeve The end in the space between pipe (2-2) and outer tube (3-2) is emitted and washes away described propeller (1-3), drives described turn Dynamic component (1-2) and light reflection element (1-1) rotate together, realize scanning of the light beam to testing sample.
  2. 2. passive drive rotation sweep optic probe according to claim 1, it is characterised in that:The end of described inner sleeve End is provided with mat.
  3. 3. passive drive rotation sweep optic probe according to claim 1, it is characterised in that:Described light focusing element Both ends of the surface are polished into oblique 8 degree of angles.
  4. 4. passive drive rotation sweep optic probe according to claim 1, it is characterised in that:Described light focusing element Anti-reflection film is coated with both ends of the surface.
  5. 5. passive drive rotation sweep optic probe according to claim 1, it is characterised in that:Described reflecting element exists Reflecting surface is coated with reflectance coating.
CN201710948116.1A 2017-10-12 2017-10-12 Passive driving rotary scanning optical probe Active CN107854114B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109913916A (en) * 2019-02-21 2019-06-21 江苏大学 A kind of device and method preparing inner wall of the pipe super-drainage structure
WO2022048062A1 (en) * 2020-09-01 2022-03-10 广州永士达医疗科技有限责任公司 Oct optical probe capable of simultaneously implementing forward and 360° lateral scanning, and implementation method therefor

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JP2013240474A (en) * 2012-05-21 2013-12-05 Olympus Corp Endoscope apparatus and endoscope washer
CN104586469A (en) * 2013-11-01 2015-05-06 上海理工大学 Local circulation type thrombus removing device
CN105769112A (en) * 2016-03-30 2016-07-20 中国科学院上海光学精密机械研究所 Optical probe for endoscopic imaging
US20160262775A1 (en) * 2015-03-13 2016-09-15 Terumo Kabushiki Kaisha Medical device
US20160270804A1 (en) * 2015-03-20 2016-09-22 Terumo Kabushiki Kaisha Medical device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1780584A (en) * 2003-04-28 2006-05-31 德州系统大学董事会 Catheter imaging probe and method
JP2013240474A (en) * 2012-05-21 2013-12-05 Olympus Corp Endoscope apparatus and endoscope washer
CN104586469A (en) * 2013-11-01 2015-05-06 上海理工大学 Local circulation type thrombus removing device
US20160262775A1 (en) * 2015-03-13 2016-09-15 Terumo Kabushiki Kaisha Medical device
US20160270804A1 (en) * 2015-03-20 2016-09-22 Terumo Kabushiki Kaisha Medical device
CN105769112A (en) * 2016-03-30 2016-07-20 中国科学院上海光学精密机械研究所 Optical probe for endoscopic imaging

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109913916A (en) * 2019-02-21 2019-06-21 江苏大学 A kind of device and method preparing inner wall of the pipe super-drainage structure
WO2022048062A1 (en) * 2020-09-01 2022-03-10 广州永士达医疗科技有限责任公司 Oct optical probe capable of simultaneously implementing forward and 360° lateral scanning, and implementation method therefor

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