CN107822633A - A kind of her abdominal segment impedance measuring method and fetal weight evaluation method - Google Patents

A kind of her abdominal segment impedance measuring method and fetal weight evaluation method Download PDF

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CN107822633A
CN107822633A CN201710880315.3A CN201710880315A CN107822633A CN 107822633 A CN107822633 A CN 107822633A CN 201710880315 A CN201710880315 A CN 201710880315A CN 107822633 A CN107822633 A CN 107822633A
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CN107822633B (en
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王萍
陈波
俞洁
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Beijing Kang Ping Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • A61B5/0537Measuring body composition by impedance, e.g. tissue hydration or fat content
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/43Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4343Pregnancy and labour monitoring, e.g. for labour onset detection
    • A61B5/4362Assessing foetal parameters

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  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

The present invention provides a kind of her abdominal segment impedance measuring method and fetal weight evaluation method, her abdominal segment impedance measuring method, comprises the following steps:Establish four port networks of her abdominal segment impedance measurement;According to four port network, the her abdominal segment impedance is calculated.Her abdominal segment impedance measuring method measurement according to embodiments of the present invention obtains her abdominal segment impedance, fetal weight is estimated based on obtained her abdominal segment impedance, B ultrasound detection, palace high measurement need not be carried out, effectively reduces fetal weight estimated cost and complexity.

Description

A kind of her abdominal segment impedance measuring method and fetal weight evaluation method
Technical field
The present invention relates to family planning technical field, in particular it relates to her abdominal segment impedance measuring method and fetus body Weight evaluation method.
Background technology
The change of fetal weight has important Research Significance, the size of fetal weight for the monitoring of gestational period pregnant woman health The selection mode to be produced of pregnant woman is directly determined, can effectively ensure that pregnant woman and fetal well-being.Fetal weight is to determine childbirth side One of an important factor for formula.
Nearly ten years, the cesarean delivery rate in China remains high, and reason is many, it is impossible to predicts fetal weight exactly It is one of major reason, doctor estimates that fetal weight is inaccurate, it is impossible to instructs pregnant woman to select childbirth options well.The opposing party Face, Estimation of fetal weight mistake, may cause occur various difficult labours during test manufacture, as shoulder dystocia, brachia plexus injury and The generation of the severe complications such as asphyxia neonatorum.Therefore, prediction fetal weight is that doctor carries out Clinical Processing to pregnant woman exactly An important evidence, and reduce the raw youngster's complication of danger and reduce the powerful guarantee of cesarean delivery rate.
At present, predict that the formula of fetal weight is more by fetus biparietal diameter, it is most of more complicated, it is difficult to remember and push away Extensively.Although fetal abdominal circumference is to predict the better index of fetal weight, the measurement of fetal abdominal circumference is by amniotic fluid volume and the shadow of the position of foetus Ring, measurement error is still larger.Because of the harmless property of ultrasonic wave, easy to use, measurement is accurate, therefore can be used to predict that fetus build is big It is small.Using ultrasonic measurement of fetal items Biological indicators, the situation of growing of fetus is not only may determine that, for accurate estimation tire Youngster's body weight is also significant.Ultrasonic Prediction fetal weight formula is a lot, document report ultrasonic measurement of fetal liver, Fetus Abdominal The factors such as hypodermis, femur length, head circumference, abdominal circumference are higher with fetal weight correlation.In practical operation, ultrasonic measurement is to inspection The person's of looking into technical merit requires higher, and various complicated situations can influence the display of abdominal circumference aspect, can not show standard aspect It is difficult to obtain accurate measurement of girth value.
In non-patent literature 1, Song Xiaofeng etc. measures the double of fetus according to the parameters such as the palace height of pregnant woman, abdominal circumference and B ultrasound The indexs such as footpath, femur length, abdominal circumference are pushed up, fetal weight estimation equation are established using mathematical method, but this method empirically return by property Return analysis, prediction result error is larger.
In non-patent literature 2, Liu Zhijun etc. considers the influence of Abdominal Wall Fat thickness and presentation height factor, fetus Body weight estimation mainly according to the high * abdominal circumferences in palace based on, but in clinical practice measurement childbirth before thickness of abdominal wall have great difficulty.
In non-patent literature 3, Yao Qin etc. utilizes B ultrasound measurement Area of fetal liver prediction fetal weight, third trimester of pregnancy fetus body The increase of weight is mainly relevant with the storage of fat accumulation and hepatic glycogen.But when cyotrophy is superfluous, Area of fetal liver increase can cause Error is larger;Meanwhile basic hospital ultrasonic measurement abdominal circumference poor accuracy, clinical practice are affected.
In non-patent literature 4, the researcher such as Wu Jun is used to measure tire using artificial intelligence approaches such as artificial neural networks Youngster's body weight, precision of prediction is improved to a certain extent, but artificial neural network also has the complicated network structure, training time length The shortcomings of, clinical verification needs to be promoted.
In non-patent literature 5, Chen Xiaotian etc. has inquired into the relation of pregnancy period precursor composition and birth weight, statistics It is relevant with the change of the various body compositions of parent to analysis shows the increase of pregnancy period body weight, but does not provide an individual composition and fetus The appraising model of body weight.
Prior art literature
Non-patent literature 1:Song Xiaofeng, Han Ping, Zou Li, Chen Dezhao, Hu Shangxu, the term fetus body based on SVMs Prediction new method [J] again, Chinese biomedical engineering journal, 2004, (06):516-522.
Non-patent literature 2:Liu Zhijun, Li Guirong, Guo Xingqiao, predict the comparison of fetal weight new method and conventional method [J], Chinese mother and child care, 2008, (24):3478-3479.
Non-patent literature 3:Yao Qin, Pan Weimin, Shao Donghong, Liu Peiqiu, B ultrasound measurement fetus liver Area Prediction fetal weight Value [J], Shandong medicine, 2003, (24):15-16.
Non-patent literature 4:Wu Jun, Yang Taizhu, Lin Jiangli, Luo Hong, Li Deyu, Wang Tianfu, Zheng Changqiong, based on artificial neuron The term fetus Weight [J] of network, biomedical engineering magazine, 2005, (05):922-925+929.
Non-patent literature 5:Chen Xiaotian, Xu Ping, Li Jie, Wang Zhiqun, Zhao Xia, Shen Shanmei, Wang Jing, Wang Shuan, pregnancy period parent The relation of composition and birth weight, Chinese mother and child care, 2015,30 (1):54-57.
Domestic gestational period pregnant woman fetal weight measurement can be seen that according to above-mentioned document analysis and be mostly based on B ultrasound, palace height etc. Method, have the following disadvantages:
(1) measuring method is all based on linear regression model (LRM) mostly, and measurement cost is higher, metering system is complicated, estimation misses Difference is larger, and measurement accuracy is had a great influence by sample size;
(2) gestational period pregnant woman need to be taken multiple measurements by pregnant week, and measurement process will ensure pregnant woman and fetal safety, increase The burden of operating personnel and the pendulous frequency of pregnant woman.
The content of the invention
In view of this, the present invention, which provides one kind, need not carry out B ultrasound detection, palace high measurement, can effectively reduce fetus body The her abdominal segment impedance measuring method and fetal weight evaluation method of weight estimated cost and complexity.
In order to solve the above technical problems, present invention employs following technical scheme:
On the one hand, her abdominal segment impedance measuring method according to embodiments of the present invention, comprises the following steps:
Establish four port networks of her abdominal segment impedance measurement;
According to four port network, the her abdominal segment impedance is calculated.
Four port networks according to embodiments of the present invention, the areal survey of her abdominal impedance can be realized, be hindered for belly The analysis of anti-and body composition transfer, pregnancy period fetal weight size estimation provide technical support.
According to some embodiments of the present invention, four port network includes two measuring electrodes and two exciting electrodes.
Alternatively, described two measuring electrodes are respectively the first measuring electrode and the second measuring electrode, and described first measures Electrode connects the left side lumbar and left lumbar of the pregnant woman, and second measuring electrode connects the waist of the side of the pregnant woman With the hip of the side;
Described two exciting electrodes are respectively the first exciting electrode and the second exciting electrode, and first exciting electrode connects The left side hip of the pregnant woman and right side hip, second exciting electrode connect the waist of the opposite side of the pregnant woman with it is described The hip of opposite side.
It is possible to further respectively by first exciting electrode and second exciting electrode to four port net Network enters row energization, is swashed with calculating with first measuring electrode, the second measuring electrode, the first exciting electrode and described second Encourage four sections of corresponding impedances of electrode.
Specifically, row energization can be entered in the both ends of first exciting electrode access scheduled current, and described in measurement Voltage difference between first exciting electrode and first measuring electrode, second measuring electrode, second exciting electrode,
The scheduled current is inputted at the both ends of second exciting electrode and enters row energization, and measures the second excitation electricity Voltage difference between pole and first measuring electrode, second measuring electrode, first exciting electrode,
According to first exciting electrode and first measuring electrode, second measuring electrode, second excitation Voltage difference between electrode, and second exciting electrode and first measuring electrode, second measuring electrode, described the Voltage difference between one exciting electrode, calculate and first measuring electrode, the second measuring electrode, the first exciting electrode, Yi Jisuo State four sections of corresponding impedances of the second exciting electrode.
On the other hand, fetal weight evaluation method according to embodiments of the present invention, comprises the following steps:
The abdomen of the pregnant woman is measured using the her abdominal segment impedance measuring method according to any of the above-described embodiment Segment section impedance;
Belly equiva lent impedance is obtained according to the belly segment impedance;
According to the belly equiva lent impedance, fetal weight appraising model is established;
According to the fetal weight appraising model and the body parameter of the pregnant woman, the fetal weight is calculated.
The calculation formula of the equiva lent impedance is shown below:
Wherein, RIt is equivalentRepresent the equiva lent impedance, R1、R2、R3、R4Four sections corresponding to four port network are represented respectively Impedance.
According to some embodiments of the present invention, the belly under 2 different frequency ranges (such as 250Hz and 500Hz) is calculated respectively Segment impedance and belly equiva lent impedance, and according to the belly segment impedance and belly equiva lent impedance under the different frequency range, And the body parameter of the pregnant woman, establish the fetal weight appraising model.
Further, the fetal weight appraising model is shown below:
Y=78* (Ti-20)+(α * H*H)/R250 is equivalent+(β*ΔW)/R500 is equivalent
Wherein, Y is fetal weight, and unit is gram (g);H is the abdominal circumference of pregnant woman, and unit is centimetre (cm);Δ W is pregnant woman's body Increase again, unit of gram (g) poor with pregestational weight during detection;TiFor pregnant week;R250 is equivalent、R500 is equivalentRepresent the 1st frequency range (i.e. respectively It is 250Hz) with reference to coefficient with the equiva lent impedance under the 2nd frequency range (i.e. 500Hz), α, β.
Further, it is described to be calculated with reference to factor alpha by following formula:
It is described to be calculated with reference to factor beta by following formula:
Wherein R250、R500、Y、H、ΔW、TiIt is test data in the 1st sample;R250'、R500'、Y'、H'、ΔW、TiFor Test data in 2nd, by R250 is equivalentIt is denoted as R250, by R500 is equivalentIt is denoted as R500, by R250 is equivalent' it is denoted as R250', by R500 is equivalentIt is denoted as R500′。
Alternatively, one group of test samples is chosen, according to actual pregnant woman's body parameter of the test samples, according to being tried to achieve The α, β value estimate the fetal weight, and compare estimation gained body weight and the actual weight of test samples, choose error Two minimum samples recalculate reference factor alpha and the β, and the fetus body is established according to α, the β for recalculating to obtain Weight appraising model.
Preferably, the Ti is more than or equal to 25.
The above-mentioned technical proposal of the present invention one of at least has the advantages that:
(1) her abdominal segment impedance measuring method provided by the invention, it can realize that the segmentation of her abdominal impedance is surveyed Amount, technical support is provided for belly impedance and the analysis of body composition transfer, pregnancy period fetal weight size estimation.
(2) a kind of fetal weight evaluation method for being based on body composition (i.e. her abdominal segment impedance) provided by the invention, Pregnancy period Estimation of fetal weight can be realized, it is not necessary to carry out B ultrasound detection, palace high measurement, effectively reduce fetal weight estimated cost With complexity.
Brief description of the drawings
Fig. 1 a are four port network human bodies point in the her abdominal segment impedance measuring method according to the embodiment of the present invention Butut, wherein, R1 represents the first exciting electrode, and R2 represents the first measuring electrode, and R3 represents the second measuring electrode, and R4 represents second Exciting electrode;
Fig. 1 b represent that electric current flows through human body schematic diagram when application electric current enters row energization on the first exciting electrode;
Fig. 1 c represent that electric current flows through human body schematic diagram when application electric current enters row energization on the second exciting electrode;
Fig. 2 represents the schematic flow sheet of fetal weight evaluation method according to embodiments of the present invention;
Fig. 3 represents to establish the flow of fetal weight appraising model in fetal weight evaluation method according to embodiments of the present invention Schematic diagram;
Fig. 4 represents the body weight and actual weight error curve of fetal weight evaluation method prediction according to embodiments of the present invention Figure;
Fig. 5 shows the body weight and actual value according to optimum prediction model prediction.
Embodiment
To make the purpose, technical scheme and advantage of the embodiment of the present invention clearer, below in conjunction with the embodiment of the present invention Accompanying drawing, the technical scheme of the embodiment of the present invention is clearly and completely described.Obviously, described embodiment is this hair Bright part of the embodiment, rather than whole embodiments.Based on described embodiments of the invention, ordinary skill The every other embodiment that personnel are obtained, belongs to the scope of protection of the invention.
Her abdominal segment impedance measuring method according to embodiments of the present invention is specifically described below in conjunction with the accompanying drawings.
Upper described her abdominal segment impedance measuring method according to embodiments of the present invention, comprises the following steps:
(1) four port networks of her abdominal segment impedance measurement are established.
In the present invention, her abdominal impedance measurement model uses the impedance network of four ports.
In order to reduce between skin and electrode influence caused by contact impedance, and can by try one's best it is few estimate it is pregnant The numerical value of woman's belly impedance, utilize four Electrode-biofilm impedance bioelectrical measurements.As shown in Fig. 1 a~Fig. 1 c, four port network includes Two measuring electrodes and two exciting electrodes.
In the example of the present invention, as shown in Figure 1a, described two measuring electrodes are respectively the first measuring electrode R2 With the second measuring electrode R3, the left side lumbar and left lumbar of the first measuring electrode R2 connections pregnant woman, the second measuring electrode The waist of the side (Fig. 1 a right side, corresponding to the left side of pregnant woman's actual body) of the R3 connections pregnant woman and the hip of the side Portion.In addition, described two exciting electrodes are respectively the first exciting electrode R1 and the second exciting electrode R4, the first exciting electrode R1 companies Connect the waist of the opposite side of the pregnant woman and hip (i.e. the first exciting electrode R1 and the second measuring electrode R3 phases of the opposite side To side), left side hip and the right side hip of the second exciting electrode R4 connections pregnant woman.
It should be noted that above-mentioned is only merely an example, for example, the first exciting electrode R1 can be with the second measurement electricity Pole R3 position is exchanged, and the second exciting electrode R4 can also be exchanged with the first measuring electrode R2 positions, or, it is above-mentioned Adjusted simultaneously first exciting electrode R1 and the second measuring electrode R3, the second exciting electrode R4 and the first measuring electrode R2 position Change.
The present invention it is described below in, for simplicity, the situation entered for Fig. 1 a~Fig. 1 c illustrates.Ability The technical staff in domain can be based on above-mentioned position and exchange, carry out her abdominal impedance measurement on the basis of described below, these Change should be all within the scope of the present invention.
(2) according to four port network, the her abdominal segment impedance is calculated.
By four port networks of above-mentioned setting, encouraged respectively by the first exciting electrode R1 (as shown in Figure 1 b) and second Electrode R4 (as illustrated in figure 1 c) enters row energization to four port network, calculates and first measuring electrode, the second measurement electricity Pole, the first exciting electrode and the corresponding four sections of impedances of second exciting electrode.
In some embodiments of the invention, at the first exciting electrode R1 both ends, access scheduled current enters row energization, and Measure voltage difference between the first exciting electrode R1 and the first measuring electrode R2, the second measuring electrode R3, the second exciting electrode R4;This Afterwards, the scheduled current is inputted at the second exciting electrode R4 both ends and enters row energization, and measure the second exciting electrode R4 and first Voltage difference between measuring electrode R2, the second measuring electrode R3, the first exciting electrode R1;Finally, according to it is above-mentioned measure first swash Encourage voltage difference between electrode R1 and the first measuring electrode R2, the second measuring electrode R3, the second exciting electrode R4, and the second excitation Voltage difference between electrode R4 and the first measuring electrode R2, the second measuring electrode R3, the first exciting electrode R1, calculate and the first measurement Electrode R2, the second measuring electrode R3, the first exciting electrode R1 and the corresponding four sections of impedances of the second exciting electrode R4.
Below, the calculating process of her abdominal segment impedance is described in detail with reference to the accompanying drawings.
When Fig. 1 b are current turns ON ac (the first exciting electrode R1), electric current flows through the schematic diagram of belly impedance.Electric current flows through Ab, bd, dc, and form parallel circuit with ac.Now, measure magnitude of voltage at upper ab, bd, dc tri- respectively, you can by voltage it Than obtaining the ratio between corresponding impedance.
As Fig. 1 c are shown as current turns ON cd (the second exciting electrode R4), electric current flows through ca, ab, bd, and with dc shapes Into parallel circuit.Now, respectively measure ca, ab, bd tri- at magnitude of voltage, you can by the ratio between voltage obtain corresponding impedance it Than.
From the measuring principle of four port circuit networks, the corresponding relation of 6 pairs of effective excitation-measurement ports can be obtained (being shown in Table 1).
The effective excitation of table 1-measurement port corresponding table
When accessing current excitation at ac ports (i.e. the first exciting electrode R1 both ends), from Fig. 1 b:
Wherein, in formula (1), electric current I is added between left lumbar region a and left crotch c, and it is V to measure the voltage obtained between a and cac-ac。
For convenience of solution, according to circuit theory, when electric current flows through same circuits, magnitude of voltage ratio is equal to it at different port Port resistive is the ratio between anti-, when electric current I is added between left lumbar region a and left crotch c, respectively in measurement Vab、Vbd、VcdVoltage at three, now It can obtain impedance R2、R3、R4Impedance value is than equation below (2) at three.
Similarly, as illustrated in figure 1 c, increase exciting current between c and d, measure the such as formula (3) of corresponding impedance, it is corresponding Formula is as follows:
Vac-ab:Vac-bd:Vac-cd=R2:R3:R4 (2)
Vcd-ac:Vcd-ab:Vcd-bd=R1:R2:R3 (3)
It can be obtained according to above-mentioned formula (2) and (3):
Further, by can be calculated:
Above-mentioned formula (5) is brought into (1) and can obtained:
Further, bring above-mentioned formula (6) into formula (5) and can be calculated her abdominal human body impedance value and be respectively:
The above-mentioned formula of abbreviation (7), formula (8), formula (9) can obtain:
Four sections of impedance R of belly1、R2、R3、R4It can be calculated by above-mentioned formula (10), (6), (11), (12).
Below, with reference to Fig. 2 and Fig. 3, fetal weight evaluation method according to embodiments of the present invention is illustrated.
As shown in Fig. 2 fetal weight evaluation method according to embodiments of the present invention, comprises the following steps:
A. first, her abdominal segment impedance is obtained.
Specifically, the above method is may be referred to be calculated.
B. then, belly equiva lent impedance is obtained according to the belly segment impedance.
For example, the calculation formula of the equiva lent impedance is shown below:
Wherein, RIt is equivalentRepresent the equiva lent impedance, R1、R2、R3、R4Four sections corresponding to four port network are represented respectively Impedance.
C. next, according to the belly equiva lent impedance, fetal weight appraising model is established.
Specifically, belly segment impedance and abdomen under 2 different frequency ranges can be calculated respectively in above-mentioned steps B Portion's equiva lent impedance, and according to the belly segment impedance and belly equiva lent impedance under the different frequency range, establish the fetus body Weight appraising model.
The fetal weight appraising model is shown below:
Y=78* (Ti-20)+(α * H*H)/R250 is equivalent+(β*ΔW)/R500 is equivalent (14)
Wherein, Y is fetal weight, unit for gram,
H be pregnant woman abdominal circumference, unit for centimetre,
Δ W is pregnant woman's body weight increase, poor with pregestational weight during detection, unit for gram,
TiFor pregnant week,
R250 is equivalent、R500 is equivalentThe 1st frequency range and the equiva lent impedance under the 2nd frequency range are represented respectively,
α, β are with reference to coefficient.
Further, tested for two samples, and factor alpha and β are referred to according to test value calculating is described.Wherein, It is described to be calculated with reference to factor alpha by following formula:
It is described to be calculated with reference to factor beta by following formula:
Wherein R250、R500、Y、H、ΔW、TiIt is test data in the 1st sample;R250'、R500'、Y'、H'、ΔW、TiFor Test data in 2nd.It should be noted that in order that formula is succinct, by R250 is equivalentIt is denoted as R250, by R500 is equivalentIt is denoted as R500, By R250 is equivalent' it is denoted as R250', by R500 is equivalentIt is denoted as R500′。
Further, in order to optimize it is described refer to coefficient, one group of test samples can be chosen, according to the test samples Actual pregnant woman's body parameter, the fetal weight is estimated according to the α that is tried to achieve, β value, and compare estimation gained body weight with The actual weight of test samples, choose two minimum samples of error recalculate it is described refer to factor alpha and β, according to counting again Obtained α, β establishes the fetal weight appraising model.
Below, α, β optimization are described in detail with reference to figure 3.
As shown in figure 3, first, initialization data, sample is divided into sample to be tested and test samples (as shown in table 1 below), Sample to be tested is combined two-by-two, forms data set L.
Using first 10 groups in table 2 as sample to be tested, combination of two between sample to be tested, estimating for fetal weight model is carried out Calculate.3 groups are used as test samples afterwards, examine the correctness of the model.
2 different pregnant weeks of table pregnancy middle and advanced stage B ultrasound partial data and belly segmentation impedance measurement partial data
Sample Fetal weight (Y) Pregnant week (Ti) Abdominal circumference average (H) R250 is equivalent ΔW R500 is equivalent
1 817.9 25 19.64 10.35 5.4 19.5
2 1192.5 26 21.62 10.45 5.8 19.8
3 1294.3 27 21.81 10.7 6.2 20.2
4 1571.2 28 22.86 9.3 6.6 17.7
5 1663.2 29 23.71 12.2 7 23.1
6 1981.1 30 24.88 10.55 7.4 19.4
7 2234.9 31 25.78 10.05 7.8 19
8 2396.1 32 26.2 10.45 8.2 19.7
9 2658.0 33 27.78 12.35 8.6 23.4
10 2780.9 34 27.99 12.2 9 23
11 2959.8 35 28.74 8.8 9.4 16.5
12 3112.2 36 29.44 10.45 9.8 19.6
13 3186.4 37 30.14 11.55 10.2 21.6
First 10 groups are sample to be tested, and sample to be tested combination of two (is denoted as respectively with the combination of sample 1 and sample 2~10 Combination 1 is denoted as combining respectively 10 to combining 17 to combination 9, with sample 2 and the combination of sample 3~10, the like) can obtain altogether The result of 45 kinds of α, β groups.In the case where this 45 kinds are combined, according to prediction body weight and the error of actual weight, obtain optimal α, β are combined.
Specifically, first, one group of sample 1 and 2 in sample to be tested data collection L is chosen, is shifted onto out according to S4 in embodiment 1 Predictor formula, shift out adjustable factor alpha, β onto, it is as follows:
Wherein R250、R500、Y、H、ΔW、TiIt is test data in the 1st sample;R250'、R500'、Y'、H'、ΔW、TiFor Test data in 2nd, by R250 is equivalentIt is denoted as R250, by R500 is equivalentIt is denoted as R500, by R250 is equivalent' it is denoted as R250', by R500 is equivalentIt is denoted as R500′。
Hereafter, corresponding α numerical value can be obtained further according to forecast body weight formula:
Then, corresponding α and β value are solved respectively using data in sample 1 and sample 2.Then with solve obtained α and β value substitutes into formula (14), to determine fetal weight appraising model.And calculate according to the body weight that body weight appraising model calculates and actual body The difference of weight.
As above, reference is above-mentioned, calculates α and β value under 45 combined situations respectively, brings formula (14) into, estimates body weight.45 The error result of specific the body weight estimation result and actual weight of combination is as shown in Figure 4.In the case where this 45 kinds are combined, root It is predicted that the error of body weight and actual weight, obtains optimal α, β combination, and determine body weight estimation mould with optimal α, β combination Pattern (14).
Hereafter, the formula (14) test samples 11 brought into after above-mentioned confirmation, fetal weight estimation is carried out.
Similarly, test samples 12,13 are also subjected to fetal weight estimation respectively.
Hereafter, it is ranked up according to error size, α and β value is recalculated with two groups of test samples during error minimum.
Fetal weight appraising model is applied to pregnancy middle and advanced stage, especially Ti>=25, that is to say, that be particularly suitable for use in 25 weeks And the estimation of fetal weight later.
D. it is last, according to the fetal weight appraising model and the body parameter of the pregnant woman, calculate the fetus body Weight.
After fetal weight appraising model is determined, joined according to fetal weight appraising model and the body of the pregnant woman Number (abdominal circumference, pregnant woman's body weight increase and the pregnant week of pregnant woman), calculates the fetal weight.
According to the α after optimization and β value and fetal weight appraising model, fetal weight is estimated, is as a result shown in figure 5。
Described above is the preferred embodiment of the present invention, it is noted that for those skilled in the art For, on the premise of principle of the present invention is not departed from, some improvements and modifications can also be made, these improvements and modifications It should be regarded as protection scope of the present invention.

Claims (12)

1. a kind of her abdominal segment impedance measuring method, it is characterised in that comprise the following steps:
Establish four port networks of her abdominal segment impedance measurement;
According to four port network, the her abdominal segment impedance is calculated.
2. her abdominal segment impedance measuring method according to claim 1, it is characterised in that the four port networks bag Include two measuring electrodes and two exciting electrodes.
3. her abdominal segment impedance measuring method according to claim 2, it is characterised in that described two measuring electrodes Respectively the first measuring electrode and the second measuring electrode, first measuring electrode connect left side lumbar and the right side of the pregnant woman Waist, second measuring electrode connect the waist of the side of the pregnant woman and the hip of the side;
Described two exciting electrodes are respectively the first exciting electrode and the second exciting electrode, described in the first exciting electrode connection The hip of the waist of the opposite side of pregnant woman and the opposite side, second exciting electrode connect the left side hip of the pregnant woman with Right side hip.
4. her abdominal segment impedance measuring method according to claim 3, it is characterised in that pass through described first respectively Exciting electrode and second exciting electrode enter row energization to four port network, with calculate with first measuring electrode, Second measuring electrode, the first exciting electrode and the corresponding four sections of impedances of second exciting electrode.
5. her abdominal segment impedance measuring method according to claim 4, it is characterised in that in the described first excitation electricity The both ends access scheduled current of pole enters row energization, and measures first exciting electrode and first measuring electrode, described the Voltage difference between two measuring electrodes, second exciting electrode,
Input the scheduled current at the both ends of second exciting electrode and enter row energization, and measure second exciting electrode with Voltage difference between first measuring electrode, second measuring electrode, first exciting electrode,
According to first exciting electrode and first measuring electrode, second measuring electrode, second exciting electrode Between voltage difference, and second exciting electrode and first measuring electrode, second measuring electrode, described first swash Voltage difference between electrode is encouraged, is calculated and first measuring electrode, the second measuring electrode, the first exciting electrode and described the Four sections of corresponding impedances of two exciting electrodes.
6. a kind of fetal weight evaluation method, it is characterised in that comprise the following steps:
The abdomen of the pregnant woman is measured using the her abdominal segment impedance measuring method according to any one of claim 1 to 5 Segment section impedance;
Belly equiva lent impedance is obtained according to the belly segment impedance;
According to the belly equiva lent impedance, fetal weight appraising model is established;
According to the fetal weight appraising model and the body parameter of the pregnant woman, the fetal weight is calculated.
7. fetal weight evaluation method according to claim 6, it is characterised in that the calculation formula of the equiva lent impedance is such as Shown in following formula:
Wherein, RIt is equivalentRepresent the equiva lent impedance, R1、R2、R3、R4Four sections of impedances corresponding to four port network are represented respectively.
8. fetal weight evaluation method according to claim 7, it is characterised in that calculate respectively under 2 different frequency ranges Belly segment impedance and belly equiva lent impedance, and according to the belly segment impedance under the different frequency range and the equivalent resistance of belly It is anti-, establish the fetal weight appraising model.
9. fetal weight evaluation method according to claim 8, it is characterised in that the fetal weight appraising model is as follows Shown in formula:
Y=78* (Ti-20)+(α*H*H)/R250 is equivalent+(β*ΔW)/R500 is equivalent
Wherein, Y is fetal weight, unit for gram,
H be pregnant woman abdominal circumference, unit for centimetre,
Δ W is pregnant woman's body weight increase, poor with pregestational weight during detection, unit for gram,
TiFor pregnant week,
R250 is equivalent、R500 is equivalentThe 1st frequency range and the equiva lent impedance under the 2nd frequency range are represented respectively,
α, β are with reference to coefficient.
10. fetal weight evaluation method according to claim 9, it is characterised in that tested for two samples, and Factor alpha and β are referred to according to test value calculating is described, wherein,
It is described to be calculated with reference to factor alpha by following formula:
It is described to be calculated with reference to factor beta by following formula:
<mrow> <mi>&amp;beta;</mi> <mo>=</mo> <mfrac> <mrow> <msub> <mi>R</mi> <mn>250</mn> </msub> <msub> <mi>R</mi> <mn>500</mn> </msub> <msup> <mi>YH</mi> <mrow> <mo>&amp;prime;</mo> <mn>2</mn> </mrow> </msup> <mo>-</mo> <mn>78</mn> <mrow> <mo>(</mo> <msub> <mi>T</mi> <mi>i</mi> </msub> <mo>-</mo> <mn>20</mn> <mo>)</mo> </mrow> <msub> <mi>R</mi> <mn>250</mn> </msub> <msub> <mi>R</mi> <mn>500</mn> </msub> <msup> <mi>H</mi> <mrow> <mo>&amp;prime;</mo> <mn>2</mn> </mrow> </msup> <mo>-</mo> <msup> <msub> <mi>R</mi> <mn>250</mn> </msub> <mo>&amp;prime;</mo> </msup> <msub> <mi>R</mi> <mn>500</mn> </msub> <mo>&amp;lsqb;</mo> <msup> <mi>Y</mi> <mo>&amp;prime;</mo> </msup> <mo>-</mo> <mn>78</mn> <mrow> <mo>(</mo> <msub> <msup> <mi>T</mi> <mo>&amp;prime;</mo> </msup> <mi>i</mi> </msub> <mo>-</mo> <mn>20</mn> <mo>)</mo> </mrow> <mo>&amp;rsqb;</mo> </mrow> <mrow> <msup> <mi>&amp;Delta;WH</mi> <mrow> <mo>&amp;prime;</mo> <mn>2</mn> </mrow> </msup> <msub> <mi>R</mi> <mn>250</mn> </msub> <mo>-</mo> <mfrac> <mrow> <msup> <msub> <mi>R</mi> <mn>250</mn> </msub> <mo>&amp;prime;</mo> </msup> <msub> <mi>R</mi> <mn>500</mn> </msub> </mrow> <mrow> <msup> <msub> <mi>R</mi> <mn>500</mn> </msub> <mo>&amp;prime;</mo> </msup> </mrow> </mfrac> <mi>&amp;Delta;</mi> <mi>W</mi> </mrow> </mfrac> <mo>,</mo> </mrow>
Wherein R250、R500、Y、H、ΔW、TiIt is test data in the 1st sample;R250'、R500'、Y'、H'、ΔW、TiFor the 2nd Test data in individual, by R250 is equivalentIt is denoted as R250, by R500 is equivalentIt is denoted as R500, by R250 is equivalent' it is denoted as R250', by R500 is equivalentIt is denoted as R500′。
11. fetal weight evaluation method according to claim 10, it is characterised in that one group of test samples is chosen, according to Actual pregnant woman's body parameters of the test samples, the fetal weight is estimated, and compares estimation according to the α that is tried to achieve, β value The actual weight of gained body weight and test samples, choose two minimum samples of error and recalculate reference factor alpha and the β, The fetal weight appraising model is established according to α, the β for recalculating to obtain.
12. fetal weight evaluation method according to claim 9, it is characterised in that the TiMore than or equal to 25.
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