CN107812313B - Transcranial magnetic stimulation target positioning method - Google Patents
Transcranial magnetic stimulation target positioning method Download PDFInfo
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- CN107812313B CN107812313B CN201711185480.3A CN201711185480A CN107812313B CN 107812313 B CN107812313 B CN 107812313B CN 201711185480 A CN201711185480 A CN 201711185480A CN 107812313 B CN107812313 B CN 107812313B
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- 238000000034 method Methods 0.000 title claims abstract description 19
- 238000011491 transcranial magnetic stimulation Methods 0.000 title claims abstract description 13
- 210000004761 scalp Anatomy 0.000 claims abstract description 37
- 210000004556 brain Anatomy 0.000 claims abstract description 10
- 210000000103 occipital bone Anatomy 0.000 claims 1
- 238000001514 detection method Methods 0.000 abstract description 2
- 210000003128 head Anatomy 0.000 description 6
- 230000002146 bilateral effect Effects 0.000 description 3
- 210000005069 ears Anatomy 0.000 description 3
- 230000006698 induction Effects 0.000 description 3
- 210000003625 skull Anatomy 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 210000005013 brain tissue Anatomy 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 230000002964 excitative effect Effects 0.000 description 1
- 230000005714 functional activity Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/004—Magnetotherapy specially adapted for a specific therapy
- A61N2/006—Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
Abstract
The invention relates to the field of medical detection, in particular to a transcranial magnetic stimulation target positioning method, which comprises the following steps: (1) acquiring a cranial magnetic resonance scanning image of a patient; (2) based on the magnetic resonance image, finding out the nearest projection point of the area to be stimulated in the brain in the image on the scalp through calculation, wherein the nearest projection point is called a scalp target point; (3) based on the magnetic resonance image, calculating the nearest distance between at least three mark points of the craniofacial area of the patient and a scalp target point on the surface of the scalp in the image; (4) and drawing a circle on the scalp by using the flexible rule respectively with the mark points as the circle centers and the distances between the flexible rule and the scalp target point as the radiuses, wherein the intersection point of the circle is the scalp target point. The method mainly depends on the calculation of the cambered surface distance of each mark point on the cranial magnetic resonance image, so the method is simple and convenient, does not need large-scale equipment, has low requirements on treatment sites, and greatly reduces the cost compared with a navigation system.
Description
Technical Field
The invention relates to the field of medical detection, in particular to a transcranial magnetic stimulation target positioning method.
Background
Transcranial Magnetic Stimulation (Transcranial Magnetic Stimulation) is a non-invasive neuro-intervention technique. Based on the principle of electromagnetic interconversion, the stimulation coil is rapidly charged and discharged to generate a time-varying induction magnetic field, and the time-varying magnetic field can generate an induction electric field and an induction current in human tissues, so that the excitatory or inhibitory regulation and control of the neuron activity in brain tissues are realized. The human brain can be divided into a plurality of sub-areas with specialized functions, and in order to adjust the functional activity of a certain abnormal brain area without influencing other normal brain areas, a body surface projection position of a specific functional area needs to be found on the surface of the scalp of a patient clinically. Because of the large individual differences in both the shape and function of the skull and brain structures, it is difficult to precisely locate the location of each patient's specific area to be stimulated without the aid of equipment. To achieve this, products on the market are mainly positioned by an infrared navigation system, which acquires a three-dimensional skull magnetic resonance scanning image to be tested, and realizes individual positioning by corresponding structures in the brain with the body surface characteristics of the scalp. However, this equipment is expensive (over 80 ten thousand), complicated to use and large in floor space. Furthermore, it requires each patient to use the device for each treatment, thus incurring significant costs for treatment with transcranial magnetic stimulation.
Disclosure of Invention
Aiming at the problems, the invention provides a method for individually positioning transcranial magnetic stimulation targets. The method mainly depends on the calculation of the cambered surface distance of each mark point on the cranial magnetic resonance image, so that large-scale equipment is not needed, and the requirement on a treatment field is low.
The invention is realized by the following technical scheme:
the transcranial magnetic stimulation target positioning method comprises the following steps:
(1) acquiring a cranial magnetic resonance scanning image of a patient;
(2) based on the magnetic resonance image, finding out the nearest projection point of the area to be stimulated in the brain in the image on the scalp through calculation, wherein the nearest projection point is called a scalp target point;
(3) based on the magnetic resonance image, calculating the nearest distance between at least three mark points of the craniofacial area of the patient and a scalp target point on the surface of the scalp in the image;
(4) and drawing a circle on the scalp by using the flexible rule respectively with the mark points as the circle centers and the distances between the flexible rule and the scalp target point as the radiuses, wherein the intersection point of the circle is the scalp target point.
Preferably, the craniofacial landmark points of step (3) include the nasion, the lowest point of the left ear, the lowest point of the right ear, the left canthus, the right canthus, and the inion.
The invention has the beneficial effects that:
the method mainly depends on the calculation of the cambered surface distance of each mark point on the cranial magnetic resonance image, so the method is simple and convenient, does not need large-scale equipment, has low requirements on treatment sites, and greatly reduces the cost compared with a navigation system. The invention can realize the individual treatment of different individuals only by using the craniocerebral magnetic resonance image and the marking points of the craniofacial part of the patient, and the single scanning image can be used for a plurality of times, thereby greatly reducing the time and money cost.
Drawings
FIG. 1 is a schematic diagram of a path magnetic stimulation target location method according to the present invention.
Detailed Description
For a better understanding of the present invention, the present invention will be further described with reference to the following examples and the accompanying drawings, which are illustrative of the present invention and are not to be construed as limiting thereof.
Example 1
The transcranial magnetic stimulation target positioning method comprises the following steps:
(1) acquiring a cranial magnetic resonance scanning image of a patient;
(2) based on the magnetic resonance image, finding out the nearest projection point of the area to be stimulated in the brain in the image on the scalp through calculation, wherein the nearest projection point is called a scalp target point;
(3) based on the magnetic resonance image, calculating the closest distance between the patient's nasion root, the lowest point of the left ear and the right ear and the scalp target point on the scalp surface in the image, and recording as A, B, C cm;
(4) the flexible rule is used for drawing a circle on the scalp by respectively taking the lowest points of the nasal root and the left and right ears as the circle centers and A, B, C cm as the radius, and the intersection point of the three circles is the scalp target point.
As shown in fig. 1, a set of numbers (A, B, C) at any point on the head, the distance between the nose root and the left and right ears, is unique. Therefore, the method firstly calculates the distance between a certain point of the head and the nasal root and the left and right ears on the cranial magnetic resonance image, then measures the distance on the head of a patient to obtain the position of the scalp target point, and starts the treatment.
Example 2
The transcranial magnetic stimulation target positioning method comprises the following steps:
(1) acquiring a cranial magnetic resonance scanning image of a patient;
(2) based on the magnetic resonance image, finding out the nearest projection point of the area to be stimulated in the brain in the image on the scalp through calculation, wherein the nearest projection point is called a scalp target point;
(3) based on the magnetic resonance image, calculating the closest distance between the occipital protuberance and the bilateral canthus of the patient in the image and the scalp target point on the scalp surface, and recording the closest distance as D, E, F cm;
(4) drawing a circle on the scalp by using a flexible rule with the occipital protuberance and the canthus on both sides as the circle centers and D, E, F cm as the radius respectively, wherein the intersection point of the three circles is the scalp target point.
The distance between any point on the head and the occipital protuberance and bilateral corners of the eye constitutes a unique set of numbers (D, E, F). Therefore, the method firstly calculates the distance between a certain point of the head and the occipital protuberance and the bilateral canthus on the cranial magnetic resonance image, then measures the distance on the head of the patient to obtain the position of the scalp target point, and starts the treatment.
The above-mentioned embodiments are merely illustrative of the preferred embodiments of the present invention, and do not limit the scope of the present invention, and various modifications and improvements made to the technical solution of the present invention by those skilled in the art without departing from the spirit of the present invention should fall within the protection scope defined by the claims of the present invention.
Claims (2)
1. The transcranial magnetic stimulation target positioning method is characterized by comprising the following steps:
(1) acquiring a cranial magnetic resonance scanning image of a patient;
(2) based on the magnetic resonance image, finding out the nearest projection point of the area to be stimulated in the brain in the image on the scalp through calculation, wherein the nearest projection point is called a scalp target point;
(3) based on the magnetic resonance image, calculating the nearest arc surface distance of at least three mark points of the craniofacial area of the patient and a scalp target point on the scalp surface in the image;
(4) and drawing a circle on the scalp by using the flexible rule respectively with the mark points as the circle centers and the distances between the flexible rule and the scalp target point as the radiuses, wherein the intersection point of the circle is the scalp target point.
2. The method for locating a transcranial magnetic stimulation target according to claim 1, wherein: the craniofacial landmark points in the step (3) comprise a nasion, a lowest point of a left ear, a lowest point of a right ear, a left canthus, a right canthus and a carina of an occipital bone.
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109215104B (en) * | 2018-09-04 | 2023-03-10 | 江文涛 | Brain structure image display method and device for transcranial stimulation treatment |
| CN112494810A (en) * | 2020-09-17 | 2021-03-16 | 杭州师范大学 | Repeated transcranial magnetic stimulation method with multi-stimulation target focusing |
| CN113577565B (en) * | 2021-08-05 | 2022-03-04 | 安徽医科大学 | Navigation positioning device of horizontal transcranial magnetic stimulator |
| CN114870261B (en) * | 2022-03-29 | 2023-08-18 | 安徽医科大学 | Scalp target positioning method, system and device based on longitude and latitude concepts |
| CN115721861B (en) * | 2022-12-06 | 2024-01-23 | 北京理工大学 | Brain-map-oriented multi-level neuron transcranial magnetic stimulation method |
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Effective date of registration: 20231008 Address after: 230032 No. 81 Mei Shan Road, Shushan District, Anhui, Hefei Patentee after: ANHUI MEDICAL University Patentee after: Ji Gongjun Address before: 230032 No. 81 Mei Shan Road, Shushan District, Anhui, Hefei Patentee before: ANHUI MEDICAL University |