CN107802708A - A kind of Chinese medicine composition for treating herpes zoster and preparation method thereof - Google Patents

A kind of Chinese medicine composition for treating herpes zoster and preparation method thereof Download PDF

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CN107802708A
CN107802708A CN201711301809.8A CN201711301809A CN107802708A CN 107802708 A CN107802708 A CN 107802708A CN 201711301809 A CN201711301809 A CN 201711301809A CN 107802708 A CN107802708 A CN 107802708A
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chinese medicine
medicine composition
herpes zoster
rhizome
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高金水
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/51—Gentianaceae (Gentian family)
    • A61K36/515—Gentiana
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
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    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The present invention discloses a kind of Chinese medicine composition for treating herpes zoster and preparation method thereof, and the Chinese medicine composition is formed by the traditional Chinese medicine of following parts by weight：10 20 parts of the root of herbaceous peony, 10 15 parts of rhizoma alismatis, 10 15 parts of Radix Angelicae Sinensis, 5 10 parts of honeysuckle, 10 20 parts of the Radix Astragali, 10 15 parts of radix bupleuri, 5 10 parts of dandelion, 5 10 parts of the dried rhizome of rehmannia, 5 10 parts of rhizome of chuanxiong, 38 parts of felwort, 38 parts of giant knotweed, 48 parts of Asian puccoon；The present invention is directed to the pathogenesis of herpes zoster, according to traditional Chinese medicine traditional theory, within support outer, treat both principal and secondary aspect of disease, focus on and improve immunity of organisms to cure the disease, evident in efficacy, have no side effect to human body, clinic is widelyd popularize.

Description

A kind of Chinese medicine composition for treating herpes zoster and preparation method thereof
Technical field
The invention belongs to tcm field, and in particular to a kind of Chinese medicine composition for treating herpes zoster, further relate to this The preparation method of Chinese medicine composition.
Background technology
Herpes zoster is the acute infection dermatoses as caused by varicella virus.To this virus without immunity Children it is infected after, varicella occurs.Turn into carrier after some patientss are infected without symptom occurs.Because virus has Neurotropism, it can be hidden for a long time after infection in the neuron of spinal nerve posterior root ganglion, when lower for the resistance or tired, sense When dye, flu, virus can regrow breeding, and move to skin along nerve fibre, and the nerve for making to be invaded and skin produce strong Strong inflammation.Fash typically has Unilateral and the characteristics of be distributed by nerve segment, is made up of the bleb of cluster, and with pain Bitterly；Age is bigger, and neuralgia is heavier.This disease is apt to occur in adult, and season in spring and autumn is common.The incidence of disease is on notable with age increase Rise.
The main harm of herpes zoster has：Serious fash and pain occur for herpes zoster acute stage；Such as malpractice or Have a delicate constitution caused by factors, " post-herpetic neuralgia " can be switched to, at least more than year, at most several years, patient will be long-term Bear affliction torment.One people falls ill, and whole family's involvement, influences quality of life；Herpes zoster also has its specific type：Herpes ophthalmicus, ear Bleb, internal organ bleb, herpetic meningitis, without herpesvirus type almost etc..These blebs both had specific characteristics, and had seriously to human body Harmfulness, some trigger intestines and stomach and urethral diseases of oozing, leave scar, can cause blindness, be deaf, or even dead.
The usual therapy of herpes zoster can not often be completely cured, even if herpes symptom is alleviated, but still gnawing pains take no rest.Chinese medicine exists There is its unique advantage on treatment herpes zoster.Pass through dispersing stagnated hepatoqi, promoting blood circulation and stopping pain, clearing heat and detoxicating, strong according to traditional Chinese medical science traditional theory The measures such as spleen and removing dampness can effectively treat herpes zoster.However, the report of current clinically rare disclosed related Chinese medicine preparation, It is badly in need of a kind of Chinese medicine composition that can effectively treat herpes zoster.
The content of the invention
In order to solve above-mentioned technical problem, the invention provides a kind of evident in efficacy, have no toxic side effect treatment to human body The Chinese medicine composition of herpes zoster.
The present invention is achieved through the following technical solutions：A kind of Chinese medicine composition for treating herpes zoster and preparation method thereof, The Chinese medicine composition is formed by the traditional Chinese medicine of following parts by weight：Root of herbaceous peony 10-20 parts, rhizoma alismatis 10-15 parts, Radix Angelicae Sinensis 10-15 parts, Honeysuckle 5-10 parts, Radix Astragali 10-20 parts, radix bupleuri 10-15 parts, dandelion 5-10 parts, dried rhizome of rehmannia 5-10 parts, rhizome of chuanxiong 5-10 parts, rough gentian Careless 3-8 parts, giant knotweed 3-8 parts, Asian puccoon 4-8 parts；
It is above-mentioned it is a kind of treat herpes zoster each bulk drug constituent analysis of Chinese medicine composition it is as follows：
The root of herbaceous peony：Nourishing blood and liver, relieved pain in delaying, hold back cloudy receipts sweat.Control chest and abdomen pain over the hypochondriac region, diarrhea dysentery abdominal pain, spontaneous sweating, deficiency of Yin hair Heat, irregular menstruation, uterine bleeding, with.
Rhizoma alismatis：It is sweet, it is cold in nature.Enter kidney, bladder warp.Li Shui, excreting dampness, expel the heat-evil.Difficult urination is controlled, oedema turgor, vomiting, is rushed down Dysentery, phlegm and retained fluid, tinea pedis, gonorrhoea, hematuria.
Radix Angelicae Sinensis：It is sweet, pungent, bitter, it is warm-natured.Enter liver, the heart, the spleen channel.Blood-nourishing and blood, tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, ease constipation are led to Just.
Honeysuckle：It is cold in nature sweet, return lung, the heart, stomach.It is clearing heat and detoxicating, wind-heat dissipating.It is red for carbuncle swells furunculosis, larynx numbness Poison, warm blood fulminant dysentery, anemopyretic cold, warm disease heating.
The Radix Astragali：Slightly warm in nature, it is sweet.Returns spleen warp, lung channel.Invigorating qi for strengthening superficies, diuresis, pus draining and toxin expelling, myogenic.The Radix Astragali using qi-restoratives as It is main, energy invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation.For insufficiency of vital energy and blood, sore caves in, purulence is into bursting or burst for a long time and does not holds back Person.The Radix Astragali has the function of good promoting pus discharge and tissue regeneration, i.e., the abscess suppuration myogenic of long disunion.Modern medicine study shows, yellow Stilbene includes and a variety of antibiotic effective ingredients, and can strengthen the immunologic function of body, therefore can be used for preventing some infectious diseases Generation.
Radix bupleuri：Bitter, pungent, cold nature.Thoughts of returning home envelope, liver, courage, tri-jiao channel.Evacuation is brought down a fever, soothing liver-qi stagnation, is risen and is lifted yang-energy. For cold, fever, fevers and chills alternate, the distending pain in hypochondrium, irregular menstruation, prolapse of the anus, the prolapse of uterus.Purging the liver of pathogenic fire heat, hypotensive.
Dandelion：It is bitter, sweet, it is cold in nature.Return liver, stomach.It is clearing heat and detoxicating, dampness removing.For pathopyretic ulcer, jaundice, heat gonorrhea, mesh Red swelling and pain.
The dried rhizome of rehmannia：It is sweet, bitter, it is cold in nature.The thoughts of returning home, liver and kidney channel.Clearing heat and cooling blood, nourishing Yin and promoting production of body fluid.For Vexed, tongue is deep red, blood Hot hematemesis, atropurpureus macula, consumption of YIN caused by febrile disease, drink of quenching one's thirst more.
Rhizome of chuanxiong：Acrid flavour, it is warm-natured.Return liver, courage, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For irregular menstruation, hypochondriac pain, chest Numbness, sore swell and ache curative, traumatic injury, headache, arthralgia pain due to rheumatism.
Felwort：Bitter, it is cold in nature.Return liver, gallbladder channel.Heat-clearing and damp-drying drug, purge the green.For jaundice with damp-heat pathogen, swelling of vulva, leukorrhea, liver Courage excess fire, hot eyes is deaf, hyperpyrexia and infantile convulsion.
Giant knotweed：Bitter, it is cold in nature.Return liver, courage, lung channel.Promoting blood circulation and stopping pain, clearing heat and promoting diuresis, removing toxic substances, preventing phlegm from forming and stopping coughing.For stasis Amenorrhea, arthralgia pain due to rheumatism, injuries from falls as well, jaundice with damp-heat pathogen, under stranguria with turbid discharge band, scald, sore and toxic, cough with lung heat.
Asian puccoon:It is sweet, it is cold in nature.The thoughts of returning home, Liver Channel.Clearing heat and cooling blood, invigorate blood circulation, removing toxic substances, promoting eruption.For maculopapulae due to toxic heat, heat toxin sore Ulcer.
Preferably, a kind of Chinese medicine composition for treating herpes zoster, is formed by the traditional Chinese medicine of following parts by weight：The root of herbaceous peony 15 Part, 13 parts of rhizoma alismatis, 12 parts of Radix Angelicae Sinensis, 6 parts of honeysuckle, 12 parts of the Radix Astragali, 12 parts of radix bupleuri, 6 parts of dandelion, 6 parts of the dried rhizome of rehmannia, 6 parts of rhizome of chuanxiong, dragon 7 parts of courage grass, 5 parts of giant knotweed, 7 parts of Asian puccoon；
It is further preferred that a kind of Chinese medicine composition for treating herpes zoster, is formed by the traditional Chinese medicine of following parts by weight：The root of herbaceous peony 15 parts, 11 parts of rhizoma alismatis, 10 parts of Radix Angelicae Sinensis, 8 parts of honeysuckle, 17 parts of the Radix Astragali, 13 parts of radix bupleuri, 9 parts of dandelion, 8 parts of the dried rhizome of rehmannia, 8 parts of rhizome of chuanxiong, 8 parts of felwort, 7 parts of giant knotweed, 7 parts of Asian puccoon；
The preparation method of the Chinese medicine composition of described treatment herpes zoster, comprises the following steps：a）Take above component raw material medicine Mixture adds appropriate amount of purified water immersion 1-2 hours；b）Slow fire decocts 2-3 hours after adding appropriate amount of purified water big fire boiling, filters Taking liquid 200-250ml, c）In kind second time taking liquid 200-250ml, after the two is well mixed, eat twice sooner or later After warmly take, 7 are a course for the treatment of.
The present invention compared with prior art, has the advantage that and had the beneficial effect that：The present invention is directed to the morbidity of herpes zoster Mechanism, according to traditional Chinese medicine traditional theory, within support outer, treat both principal and secondary aspect of disease, focus on and improve immunity of organisms to cure the disease, curative effect shows Write, have no side effect to human body, clinic is widelyd popularize.
Embodiment
Embodiment 1：
It is used for the Chinese medicine composition for treating herpes zoster described in the present embodiment, is formed by the traditional Chinese medicine of following parts by weight：The root of herbaceous peony 15 parts, 13 parts of rhizoma alismatis, 12 parts of Radix Angelicae Sinensis, 6 parts of honeysuckle, 12 parts of the Radix Astragali, 12 parts of radix bupleuri, 6 parts of dandelion, 6 parts of the dried rhizome of rehmannia, 6 parts of rhizome of chuanxiong, 7 parts of felwort, 5 parts of giant knotweed, 7 parts of Asian puccoon；
The preparation method of medicine of the present invention, comprises the following steps：a）Above component raw material medicine mixture is taken to add appropriate amount of purified water Immersion 2 hours；b）Slow fire decocts 2 hours after adding appropriate amount of purified water big fire boiling, filtering extracting liquid 250ml, c）In kind Second time taking liquid 250ml, after the two is well mixed, warmly take after the meal twice sooner or later, 7 are a course for the treatment of.
Embodiment 2：
It is used for the Chinese medicine composition for treating herpes zoster described in the present embodiment, is formed by the traditional Chinese medicine of following parts by weight：The root of herbaceous peony 15 parts, 11 parts of rhizoma alismatis, 10 parts of Radix Angelicae Sinensis, 8 parts of honeysuckle, 17 parts of the Radix Astragali, 13 parts of radix bupleuri, 9 parts of dandelion, 8 parts of the dried rhizome of rehmannia, 8 parts of rhizome of chuanxiong, 8 parts of felwort, 7 parts of giant knotweed, 7 parts of Asian puccoon；
The preparation method of medicine of the present invention, comprises the following steps：a）Above component raw material medicine mixture is taken to add appropriate amount of purified water Immersion 2 hours；b）Slow fire decocts 2 hours after adding appropriate amount of purified water big fire boiling, filtering extracting liquid 250ml, c）In kind Second time taking liquid 250ml, after the two is well mixed, warmly take after the meal twice sooner or later, 7 are a course for the treatment of.
Presently preferred embodiments of the present invention is the foregoing is only, and corresponding limitation is made to the present invention；It is all the present invention Within spirit and principle, any modification, equivalent substitution and improvements made etc., it should be included in the scope of the protection.

Claims (4)

1. a kind of Chinese medicine composition for treating herpes zoster, it is characterised in that the Chinese medicine composition is by following parts by weight Medicine is formulated：Root of herbaceous peony 10-20 parts, rhizoma alismatis 10-15 parts, Radix Angelicae Sinensis 10-15 parts, honeysuckle 5-10 parts, Radix Astragali 10-20 parts, radix bupleuri 10-15 parts, dandelion 5-10 parts, dried rhizome of rehmannia 5-10 parts, rhizome of chuanxiong 5-10 parts, felwort 3-8 parts, giant knotweed 3-8 parts, Asian puccoon 4-8 parts.
A kind of 2. Chinese medicine composition for treating herpes zoster according to claim 1, it is characterised in that the Chinese traditional medicine composition Thing is formed by the traditional Chinese medicine of following parts by weight：15 parts of the root of herbaceous peony, 13 parts of rhizoma alismatis, 12 parts of Radix Angelicae Sinensis, 6 parts of honeysuckle, 12 parts of the Radix Astragali, bavin 12 parts recklessly, 6 parts of dandelion, 6 parts of the dried rhizome of rehmannia, 6 parts of rhizome of chuanxiong, 7 parts of felwort, 5 parts of giant knotweed, 7 parts of Asian puccoon.
A kind of 3. Chinese medicine composition for treating herpes zoster according to claim 1, it is characterised in that the Chinese traditional medicine composition Thing is formed by the traditional Chinese medicine of following parts by weight：15 parts of the root of herbaceous peony, 11 parts of rhizoma alismatis, 10 parts of Radix Angelicae Sinensis, 8 parts of honeysuckle, 17 parts of the Radix Astragali, bavin 13 parts recklessly, 9 parts of dandelion, 8 parts of the dried rhizome of rehmannia, 8 parts of rhizome of chuanxiong, 8 parts of felwort, 7 parts of giant knotweed, 7 parts of Asian puccoon.
A kind of 4. preparation method of the Chinese medicine composition for the treatment of herpes zoster as described in claim 1-3, it is characterised in that：Bag Include following steps：a）Above component raw material medicine mixture is taken to add appropriate amount of purified water immersion 1-2 hours；b）Add appropriate amount of purified water big Slow fire decocts 2-3 hours, filtering extracting liquid 200-250ml, c after fire boiling）In kind second time taking liquid 200- 250ml, after the two is well mixed, warmly take after the meal twice sooner or later, 7 are a course for the treatment of.
CN201711301809.8A 2017-12-10 2017-12-10 A kind of Chinese medicine composition for treating herpes zoster and preparation method thereof Pending CN107802708A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114767817A (en) * 2022-05-09 2022-07-22 山西医科大学第二医院 Traditional Chinese medicine composition for treating herpes zoster

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114767817A (en) * 2022-05-09 2022-07-22 山西医科大学第二医院 Traditional Chinese medicine composition for treating herpes zoster
CN114767817B (en) * 2022-05-09 2023-03-21 山西医科大学第二医院 Traditional Chinese medicine composition for treating herpes zoster

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