CN107798218A - A kind of biological data visualization method and device - Google Patents

A kind of biological data visualization method and device Download PDF

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Publication number
CN107798218A
CN107798218A CN201711015834.XA CN201711015834A CN107798218A CN 107798218 A CN107798218 A CN 107798218A CN 201711015834 A CN201711015834 A CN 201711015834A CN 107798218 A CN107798218 A CN 107798218A
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client
browser
receptor protein
drug ligand
biological data
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路建波
马旭
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Science Technology Research Institute Of National Health And Family Planning Commission Of People's Republick Of China
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Science Technology Research Institute Of National Health And Family Planning Commission Of People's Republick Of China
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Priority to CN201711015834.XA priority Critical patent/CN107798218A/en
Publication of CN107798218A publication Critical patent/CN107798218A/en
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    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F16/00Information retrieval; Database structures therefor; File system structures therefor
    • G06F16/90Details of database functions independent of the retrieved data types
    • G06F16/95Retrieval from the web
    • G06F16/957Browsing optimisation, e.g. caching or content distillation
    • G06F16/9574Browsing optimisation, e.g. caching or content distillation of access to content, e.g. by caching
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B45/00ICT specially adapted for bioinformatics-related data visualisation, e.g. displaying of maps or networks

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Evolutionary Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

In the embodiment of the present invention, a kind of biological data visualization method is proposed, including:Client receives browser OPEN, and browser is opened according to the browser OPEN;The client receives the biological data information in the target pages input of the browser, and the biological data information is sent to server;The client receives the target organism data that the server obtains according to the biological data information;The client visualizes the material that the target organism data are characterized by the browser in three dimensions;In this scenario, the special visual software of user's additional downloads is not needed, the material that user is characterized biological data by browser can visualizes, and browser is usually one of indispensable software of user, therefore, can solve to need to take the defects of user local internal memory and complexity are higher caused by the special visual software of additional downloads, installation due to needing present in prior art.

Description

A kind of biological data visualization method and device
Technical field
The present invention relates to technical field of information display, more particularly to a kind of biological data visualization method and device.
Background technology
Due to the complexity and higher-dimension of biological data, it is not easy to be represented with numerical expression, is also not easy to use logical formula Represent, and by the visual means of data, people can be helped to be readily recognised and understood biological sequence, and then analyze and explain Data, make people find out hiding rule from rambling data, and foundation is provided for scientific discovery.Therefore, pass through at present Visual means show that biological data seems more and more important.
At present, the process for visualizing biological data is mainly, and user is in advance in locally-installed docking processing software and visual Change software, then, biological data is imported into docking processing software and carries out docking processing, then the biological data after docking is handled is used Local visual software is shown.
Because user needs therefore, to deposit in locally-installed docking processing software and visual software in advance in the above method Need to take the internal memory of user's local terminal, and need user that software is installed in advance, the defects of increasing complexity.
The content of the invention
In view of the above problems, it is proposed that the present invention, overcome above mentioned problem to provide one kind or solve at least in part A kind of the biological data visualization method and device of above mentioned problem, for solving to need to take user present in prior art The defects of internal memory and higher complexity of local terminal.
In the first aspect of embodiment of the present invention, there is provided a kind of biological data visualization method, including:
Client receives browser OPEN, and browser is opened according to the browser OPEN;
The client receives the biological data information that the target pages in the browser input, and by the biological number It is believed that breath is sent to server;
The client receives the target organism data that the server obtains according to the biological data information;
The client visualizes the material that the target organism data are characterized by the browser in three dimensions.
In one embodiment, the method according to the above-mentioned embodiment of the present invention, the biological data information Including at least one of Drug Ligand numbering, receptor protein numbering and docking area information.
In some embodiments, the method according to any of the above-described embodiment of the present invention, client's termination The target organism data that the server obtains according to the biological data information are received, including:
The client receives the server and handles Drug Ligand file docking corresponding to Drug Ligand numbering Receptor protein file corresponding to rear Drug Ligand file, the receptor protein found numbering.
In some embodiments, the method according to any of the above-described embodiment of the present invention, the client are led to Cross the browser and visualize the material that the target organism data are characterized in three dimensions, including:
The client uses the online visualization technique storehouse of molecule by the target organism data institute by the browser The material of sign is visualized in three dimensions.
In some embodiments, the method according to any of the above-described embodiment of the present invention, the client are led to Cross material that the browser is characterized the target organism data with the online visualization technique storehouse of molecule in three dimensions Visualized, including:
The client determines the acceptor egg with the online visualization technique storehouse of molecule according to the docking area information White target position;
The target that the Drug Ligand of three dimensional form is moved in the receptor protein of three dimensional form by the client Point opening position.
In some embodiments, the method according to any of the above-described embodiment of the present invention, methods described are also wrapped Include:
The client pre-set the receptor protein be format surface, the Drug Ligand be mallet form;
The target that the Drug Ligand of three dimensional form is moved in the receptor protein of three dimensional form by the client Point opening position, including:
The Drug Ligand of mallet form is moved to the target position of the receptor protein of format surface by the client Place.
In some embodiments, the method according to any of the above-described embodiment of the present invention, the client are pre- First to set the receptor protein be format surface, the Drug Ligand is mallet form, including:
The client pre-sets the receptor protein as format surface, institute by addrepresentative functions It is mallet form to state Drug Ligand.
In some embodiments, the method according to any of the above-described embodiment of the present invention, the client will The Drug Ligand of three dimensional form is moved at the target position in the receptor protein of three dimensional form, including:
The Drug Ligand of three dimensional form is moved to three-dimensional shaped by the client according to movecomponent functions At target position in the receptor protein of formula.
In some embodiments, the method according to any of the above-described embodiment of the present invention, the client will Before the Drug Ligand of three dimensional form is moved at the target position in the receptor protein of three dimensional form, in addition to:
The client loads Drug Ligand and receptor protein file by loadfile functions;
The client loads docking area information by addbox functions.
In some embodiments, the method according to any of the above-described embodiment of the present invention, if the target is given birth to Thing data are the Drug Ligand data after processing and the receptor protein data found, and methods described also includes:
The client receives docking operation idsplay order, and according to the docking operation idsplay order Dynamic Announce The Drug Ligand of Drug Ligand data characterization is from initial position dynamic mobile to the receptor protein of the receptor protein data characterization Process.
In the second aspect of embodiment of the present invention, there is provided a kind of biological data visible apparatus, including:
Receiving unit, for receiving browser OPEN;
Opening unit, for opening browser according to the browser OPEN;
The receiving unit is additionally operable to, and receives the biological data information in the target pages input of the browser;
Transmitting element, for the biological data information to be sent to server;
The receiving unit is additionally operable to, and receives the target organism number that the server obtains according to the biological data information According to;
Visualization, for visualizing what the target organism data were characterized in three dimensions by the browser Material.
In one embodiment, the device according to the above-mentioned embodiment of the present invention, the biological data information Including at least one of Drug Ligand numbering, receptor protein numbering and docking area information.
In some embodiments, the device according to any of the above-described embodiment of the present invention, the receiving unit The target organism data that the server obtains according to the biological data information are received, are specially:
The server is received to match somebody with somebody the medicine after Drug Ligand file docking processing corresponding to Drug Ligand numbering Receptor protein file corresponding to body file, the receptor protein found numbering.
In some embodiments, the device according to any of the above-described embodiment of the present invention, the visualization are single Member visualizes the material that the target organism data are characterized by the browser in three dimensions, including:
The material for being characterized the target organism data with the online visualization technique storehouse of molecule by the browser Visualized in three dimensions.
In some embodiments, the device according to any of the above-described embodiment of the present invention, the visualization are single Member includes determining unit and mobile unit, wherein:
The determining unit, for using the online visualization technique storehouse of molecule according to determining the docking area information The target position of receptor protein;
The mobile unit, for the Drug Ligand of three dimensional form to be moved to the receptor protein of three dimensional form In target position at.
In some embodiments, the device according to any of the above-described embodiment of the present invention, described device are also wrapped Include setting unit, for pre-setting the receptor protein be format surface, the Drug Ligand be mallet form;
The Drug Ligand of three dimensional form is moved in the receptor protein of three dimensional form by the mobile unit At target position, it is specially:
At the target position for the receptor protein that the Drug Ligand of mallet form is moved into format surface.
In some embodiments, the device according to any of the above-described embodiment of the present invention, the setting unit Pre-set the receptor protein be format surface, the Drug Ligand be mallet form, be specially:
By addrepresentative functions, the receptor protein is pre-set as format surface, the Drug Ligand For mallet form.
In some embodiments, the device according to any of the above-described embodiment of the present invention, the mobile unit The Drug Ligand of three dimensional form is moved at the target position in the receptor protein of three dimensional form, is specially:
According to movecomponent functions, by the Drug Ligand of three dimensional form be moved to described in three dimensional form by At target position in body protein.
In some embodiments, the device according to any of the above-described embodiment of the present invention, described device are also wrapped Loading unit is included, for loading Drug Ligand and receptor protein file by loadfile functions;Loaded by addbox functions Dock area information.
In some embodiments, the device according to any of the above-described embodiment of the present invention, if the target is given birth to Thing data are the Drug Ligand data after processing and the receptor protein data found, and the receiving unit is additionally operable to, reception pair Termination process idsplay order;
Also include dynamic display unit, for the Drug Ligand number according to the docking operation idsplay order Dynamic Announce According to the Drug Ligand of sign from initial position dynamic mobile to the process of the receptor protein of the receptor protein data characterization.
In the embodiment of the present invention, a kind of biological data visualization method is proposed, including:Client receives browser and opened Instruction, browser is opened according to the browser OPEN;The client reception is defeated in the target pages of the browser The biological data information entered, and the biological data information is sent to server;The client receives the server root The target organism data obtained according to the biological data information;The client is visualized in three dimensions by the browser The material that the target organism data are characterized;In this scenario, it is not necessary to the special visual software of user's additional downloads, The material that user is characterized biological data by browser can visualizes, and browser is usually the indispensable software of user One of, therefore, can solve present in prior art by needing the special visual software institute band of additional downloads, installation The defects of that comes needs to take the internal memory and higher complexity of user local.
Brief description of the drawings
Detailed description below, above-mentioned and other mesh of exemplary embodiment of the invention are read by reference to accompanying drawing , feature and advantage will become prone to understand.In the accompanying drawings, if showing the present invention's by way of example, and not by way of limitation Dry embodiment, wherein:
Fig. 1 schematically shows a kind of visual flow chart of biological data in the embodiment of the present invention;
Fig. 2 schematically shows a kind of visual schematic diagram of receptor protein in the embodiment of the present invention;
Fig. 3 schematically shows a kind of visual schematic diagram of Drug Ligand in the embodiment of the present invention;
Fig. 4 schematically shows the visual another schematic diagram of receptor protein in the embodiment of the present invention;
Fig. 5 schematically shows the visual another schematic diagram of Drug Ligand in the embodiment of the present invention;
Fig. 6 schematically shows a kind of visual schematic diagram of box in the embodiment of the present invention;
Fig. 7, which is schematically shown, to be carried visual one kind of receptor protein of Drug Ligand and shows in the embodiment of the present invention It is intended to;
The visualization that Fig. 8 schematically shows the process that Drug Ligand in the embodiment of the present invention is moved to receptor protein is shown It is intended to;
The visualization that Fig. 9 schematically shows the process that Drug Ligand in the embodiment of the present invention is moved to receptor protein is shown It is intended to;
Figure 10 schematically shows the schematic diagram of biological data visible apparatus in the embodiment of the present invention;
By reading the detailed description of hereafter preferred embodiment, it is various other the advantages of and benefit it is common for this area Technical staff will be clear understanding.Accompanying drawing is only used for showing the purpose of preferred embodiment, and is not considered as to the present invention Limitation.And in whole accompanying drawing, identical part is denoted by the same reference numerals.
Embodiment
The exemplary embodiment of the disclosure is more fully described below with reference to accompanying drawings.Although the disclosure is shown in accompanying drawing Exemplary embodiment, it being understood, however, that may be realized in various forms the disclosure without should be by embodiments set forth here Limited.On the contrary, these embodiments are provided to facilitate a more thoroughly understanding of the present invention, and can be by the scope of the present disclosure Completely it is communicated to those skilled in the art.
As shown in fig.1, in the embodiment of the present invention, a kind of biological data visualization method 10 is proposed, including:
Step 100:Client receives browser OPEN, and browser is opened according to the browser OPEN;
Step 110:The client receives the biological data information that the target pages in the browser input, and by institute Biological data information is stated to send to server;
Step 120:The client receives the target organism number that the server obtains according to the biological data information According to;
Step 130:The client visualizes target organism data institute table in three dimensions by the browser The material of sign.
It should be noted that visual material can be receptor protein in three dimensions, as shown in Fig. 2 or, can be with It is Drug Ligand, or can also is other targets as shown in figure 3, it is of course also possible to be the receptor protein for docking Drug Ligand The material that biological data is characterized, is not specifically limited herein.
Wherein, alternatively, the biological data information includes Drug Ligand numbering, receptor protein numbering and docking region letter At least one of breath.
In the embodiment of the present invention, the client receives the target that the server obtains according to the biological data information During biological data, it is alternatively possible in the following way:
The client receives the server and handles Drug Ligand file docking corresponding to Drug Ligand numbering Receptor protein file corresponding to rear Drug Ligand file, the receptor protein found numbering.
That is, user need not import specific Drug Ligand file and receptor protein file in client, only need Drug Ligand numbering, receptor protein numbering are inputted, server can search corresponding file, and the file found is transmitted To client, so, client avoids the need for storing receptor protein file and Drug Ligand file, saves the storage money of client Source.
Wherein, processing can be docked using autodock technologies during server docking processing Drug Ligand file, mainly Process is:Server uses the amino acid residue around receptor protein activity site to form a box (Box), then uses inhomogeneity The atom of type is scanned as probe (probe), calculates lattice point energy, this part operation is mainly by server Autogrid programs are completed, and then autodock programs carry out stable conformation to Drug Ligand in the range of Box (conformational search), finally according to the tripe systems of Drug Ligand as (conformation) is scored, such as root (scoring) is scored according to the direction (orientation) of Drug Ligand, position (position) and energy (energy), Finally scoring is ranked up (ranking), and the highest that will score, the i.e. conformation of sequence first pass client back for final result (browser).
In the embodiment of the present invention, the client visualizes the target organism number in three dimensions by the browser Have according to the mode of the material characterized it is a variety of, it is alternatively possible in the following way:
The client uses the online visualization technique storehouse of molecule by the target organism data institute by the browser The material of sign is visualized in three dimensions.
Wherein, the client uses the online visualization technique storehouse of molecule by the target organism number by the browser When being visualized in three dimensions according to the material characterized, it is alternatively possible in the following way:
The client determines the acceptor egg with the online visualization technique storehouse of molecule according to the docking area information White target position;
The target that the Drug Ligand of three dimensional form is moved in the receptor protein of three dimensional form by the client Point opening position.
Further, methods described also includes:
The client pre-set the receptor protein be format surface, the Drug Ligand be mallet form;
It is that the client is by three dimensional form in the case that mallet form, receptor protein are format surface in Drug Ligand Drug Ligand when being moved at the target position in the receptor protein of three dimensional form, can be in the following way:
The Drug Ligand of mallet form is moved to the target position of the receptor protein of format surface by the client Place.
Wherein, the client pre-set the receptor protein be format surface, the Drug Ligand be mallet form When, alternatively, in the following way:
The client pre-sets the receptor protein as format surface, institute by addrepresentative functions It is mallet form to state Drug Ligand.
Wherein, the Drug Ligand of three dimensional form is moved in the receptor protein of three dimensional form by the client Target position at when, it is alternatively possible in the following way:
The Drug Ligand of three dimensional form is moved to three-dimensional shaped by the client according to movecomponent functions At target position in the receptor protein of formula.
It is therefore, further, described, it is necessary to first load the material before the material that visualization biological data is characterized Before the Drug Ligand of three dimensional form is moved at the target position in the receptor protein of three dimensional form by client, Also include:
The client loads Drug Ligand and receptor protein file by loadfile functions;
The client loads docking area information by addbox functions.
Previously described visualization is one static result of visualization, such as to being connected to the acceptor egg of Drug Ligand In vain, still, it is further, described in order to allow user to recognize Drug Ligand is how to be docked to receptor protein this process Method also includes:
The client receives docking operation idsplay order, and according to the docking operation idsplay order Dynamic Announce The Drug Ligand of Drug Ligand data characterization is from initial position dynamic mobile to the receptor protein of the receptor protein data characterization Process.
In order to illustrate such scheme, specific example shown below is.
Step 1:The numbering of input frame input receptor protein corresponding to albumen id of the user in the target pages of browser, Such as " 2hsl ";
After performing step 1, receptor protein corresponding to " 2hsl " is presented in browser, Fig. 4 illustrates this receptor albumen Part.
Step 2:The volume of input frame input Drug Ligand corresponding to small analysis id of the user in the target pages of browser Number, such as " ZINC08644971 ";
Receptor protein corresponding to " 2hsl " not only is presented after performing step 2, in browser, is also presented Drug Ligand corresponding to " ZINC08644971 ", as shown in Figure 5.
Step 3:Docking area information input frame input relevant information of the user in the target pages of browser;
The centre coordinate (0,0,30) and value range (30,30,30) in docking region are such as inputted, now, in the mesh of browser Box 3D models can be also presented in face by demarcating, as shown in Figure 6.
Step 4:" submission operation " button that user is clicked in the target pages of browser, medicine is presented in browser and matches somebody with somebody Body has moved to the receptor protein of receptor protein, as shown in Figure 7.
In order to be even further appreciated that docking, can also further show check Drug Ligand and receptor protein to taking over Journey, as shown in Figure 8.
In the embodiment of the present invention, homepage corresponding to target pages can include web site name, platform introduction, frame retrieval, Landing frame, at least one of function such as dock door, molecule 3D visual presentations is submitted online, as shown in Figure 9.
As shown in fig.10, in the embodiment of the present invention, it is also proposed that a kind of biological data visible apparatus, including:
Receiving unit 200, for receiving browser OPEN;
Opening unit 210, for opening browser according to the browser OPEN;
The receiving unit 200 is additionally operable to, and receives the biological data information in the target pages input of the browser;
Transmitting element 220, for the biological data information to be sent to server;
The receiving unit 200 is additionally operable to, and is received the target that the server obtains according to the biological data information and is given birth to Thing data;
Visualization 230, for visualizing target organism data institute table in three dimensions by the browser The material of sign.
In the embodiment of the present invention, alternatively, the biological data information include Drug Ligand numbering, receptor protein numbering and Dock at least one of area information.
In the embodiment of the present invention, alternatively, the receiving unit 200 receives the server to be believed according to the biological data Obtained target organism data are ceased, are specially:
The server is received to match somebody with somebody the medicine after Drug Ligand file docking processing corresponding to Drug Ligand numbering Receptor protein file corresponding to body file, the receptor protein found numbering.
In the embodiment of the present invention, alternatively, the visualization 230 is visualized in three dimensions by the browser The material that the target organism data are characterized, including:
The material for being characterized the target organism data with the online visualization technique storehouse of molecule by the browser Visualized in three dimensions.
In the embodiment of the present invention, alternatively, the visualization 230 includes determining unit 230A and mobile unit 230B, wherein:
The determining unit 230A, for being determined with the online visualization technique storehouse of molecule according to the docking area information The target position of the receptor protein;
The mobile unit 230B, for the Drug Ligand of three dimensional form to be moved to the acceptor of three dimensional form At target position in albumen.
In the embodiment of the present invention, further, described device also includes setting unit 240, for pre-set it is described by Body protein is format surface, the Drug Ligand is mallet form;
The Drug Ligand of three dimensional form is moved to the receptor protein of three dimensional form by the mobile unit 230B In target position at, be specially:
At the target position for the receptor protein that the Drug Ligand of mallet form is moved into format surface.
In the embodiment of the present invention, alternatively, the setting unit 240 pre-set the receptor protein for format surface, The Drug Ligand is mallet form, is specially:
By addrepresentative functions, the receptor protein is pre-set as format surface, the Drug Ligand For mallet form.
In the embodiment of the present invention, alternatively, the Drug Ligand of three dimensional form is moved to by the mobile unit 230B At target position in the receptor protein of three dimensional form, it is specially:
According to movecomponent functions, by the Drug Ligand of three dimensional form be moved to described in three dimensional form by At target position in body protein.
In the embodiment of the present invention, further, described device also includes loading unit 250, for passing through loadfile letters Number loading Drug Ligand and receptor protein file;Docking area information is loaded by addbox functions.
In the embodiment of the present invention, further, if the target organism data is the Drug Ligand data after processing and look into The receptor protein data found, the receiving unit 200 are additionally operable to, and receive docking operation idsplay order;
Also include dynamic display unit 260, match somebody with somebody for the medicine according to the docking operation idsplay order Dynamic Announce The Drug Ligand that volume data characterizes is from initial position dynamic mobile to the process of the receptor protein of the receptor protein data characterization.
It should be noted that although being referred to some units of device in above-detailed, but this division is only simultaneously Non-imposed.In fact, according to the embodiment of the present invention, the feature and function of two or more above-described units can To embody in a unit.Conversely, the feature and function of an above-described unit can be further divided into by more Individual unit embodies.
In addition, although the operation of the inventive method is described with particular order in the accompanying drawings, still, this do not require that or Hint must perform these operations according to the particular order, or the operation having to carry out shown in whole could realize it is desired As a result.Additionally or alternatively, it is convenient to omit some steps, multiple steps are merged into a step and performed, and/or by one Step is decomposed into execution of multiple steps.
Although describe spirit and principles of the present invention by reference to some embodiments, it should be appreciated that, this Invention is not limited to disclosed embodiment, and the division to each side does not mean that the feature in these aspects can not yet Combination is to be benefited, and this division is merely to the convenience of statement.It is contemplated that cover appended claims spirit and In the range of included various modifications and equivalent arrangements.

Claims (10)

1. a kind of biological data visualization method, including:
Client receives browser OPEN, and browser is opened according to the browser OPEN;
The client receives the biological data information in the target pages input of the browser, and the biological data is believed Breath is sent to server;
The client receives the target organism data that the server obtains according to the biological data information;
The client visualizes the material that the target organism data are characterized by the browser in three dimensions.
2. the method as described in claim 1, the biological data information includes Drug Ligand numbering, receptor protein is numbered and right Connect at least one of area information.
3. method as claimed in claim 2, the client receives the server and obtained according to the biological data information Target organism data, including:
The client receives the server by after Drug Ligand file docking processing corresponding to Drug Ligand numbering Receptor protein file corresponding to Drug Ligand file, the receptor protein found numbering.
4. method as claimed in claim 3, the client visualizes the target in three dimensions by the browser The material that biological data is characterized, including:
The client is characterized the target organism data with the online visualization technique storehouse of molecule by the browser Material visualized in three dimensions.
5. method as claimed in claim 4, the client uses the online visualization technique storehouse of molecule by the browser The material that the target organism data are characterized is visualized in three dimensions, including:
The client determines the receptor protein with the online visualization technique storehouse of molecule according to the docking area information Target position;
The target spot position that the Drug Ligand of three dimensional form is moved in the receptor protein of three dimensional form by the client Put place.
6. method as claimed in claim 5, methods described also include:
The client pre-set the receptor protein be format surface, the Drug Ligand be mallet form;
The target spot position that the Drug Ligand of three dimensional form is moved in the receptor protein of three dimensional form by the client Place is put, including:
At the target position for the receptor protein that the Drug Ligand of mallet form is moved to format surface by the client.
7. method as claimed in claim 6, the client pre-sets the receptor protein as format surface, the medicine Part is mallet form, including:
The client pre-sets the receptor protein as format surface, the medicine by addrepresentative functions Thing part is mallet form.
8. method as claimed in claim 5, the Drug Ligand of three dimensional form is moved to three dimensional form by the client The receptor protein in target position at, including:
The Drug Ligand of three dimensional form is moved to three dimensional form by the client according to movecomponent functions At target position in the receptor protein.
9. the method as described in claim any one of 1-8, if the target organism data are the Drug Ligand data after processing With the receptor protein data found, methods described also includes:
The client receives docking operation idsplay order, and the medicine according to the docking operation idsplay order Dynamic Announce The Drug Ligand of part data characterization is from initial position dynamic mobile to the mistake of the receptor protein of the receptor protein data characterization Journey.
10. a kind of biological data visible apparatus, including:
Receiving unit, for receiving browser OPEN;
Opening unit, for opening browser according to the browser OPEN;
The receiving unit is additionally operable to, and receives the biological data information in the target pages input of the browser;
Transmitting element, for the biological data information to be sent to server;
The receiving unit is additionally operable to, and receives the target organism data that the server obtains according to the biological data information;
Visualization, for visualizing the thing that the target organism data are characterized in three dimensions by the browser Matter.
CN201711015834.XA 2017-10-25 2017-10-25 A kind of biological data visualization method and device Pending CN107798218A (en)

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