CN107790037A - A kind of tolylsulfonylurea production agitating device - Google Patents
A kind of tolylsulfonylurea production agitating device Download PDFInfo
- Publication number
- CN107790037A CN107790037A CN201711250461.4A CN201711250461A CN107790037A CN 107790037 A CN107790037 A CN 107790037A CN 201711250461 A CN201711250461 A CN 201711250461A CN 107790037 A CN107790037 A CN 107790037A
- Authority
- CN
- China
- Prior art keywords
- fixedly connected
- casing
- rotating shaft
- agitating device
- tolylsulfonylurea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 24
- 238000009434 installation Methods 0.000 claims abstract description 14
- 239000004744 fabric Substances 0.000 claims description 9
- 238000003756 stirring Methods 0.000 claims description 7
- 230000003628 erosive effect Effects 0.000 claims description 4
- 239000000463 material Substances 0.000 claims 1
- 239000002994 raw material Substances 0.000 abstract description 6
- 238000007599 discharging Methods 0.000 abstract description 4
- 238000002156 mixing Methods 0.000 abstract description 2
- BOVGTQGAOIONJV-BETUJISGSA-N 1-[(3ar,6as)-3,3a,4,5,6,6a-hexahydro-1h-cyclopenta[c]pyrrol-2-yl]-3-(4-methylphenyl)sulfonylurea Chemical compound C1=CC(C)=CC=C1S(=O)(=O)NC(=O)NN1C[C@H]2CCC[C@H]2C1 BOVGTQGAOIONJV-BETUJISGSA-N 0.000 description 2
- JLRGJRBPOGGCBT-UHFFFAOYSA-N Tolbutamide Chemical compound CCCCNC(=O)NS(=O)(=O)C1=CC=C(C)C=C1 JLRGJRBPOGGCBT-UHFFFAOYSA-N 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229960000346 gliclazide Drugs 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 229940123208 Biguanide Drugs 0.000 description 1
- 102100024295 Maltase-glucoamylase Human genes 0.000 description 1
- 229940100389 Sulfonylurea Drugs 0.000 description 1
- 108010028144 alpha-Glucosidases Proteins 0.000 description 1
- 239000003472 antidiabetic agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 150000004283 biguanides Chemical class 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000003139 buffering effect Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 229940126904 hypoglycaemic agent Drugs 0.000 description 1
- 230000002218 hypoglycaemic effect Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000837 restrainer Substances 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- YROXIXLRRCOBKF-UHFFFAOYSA-N sulfonylurea Chemical class OC(=N)N=S(=O)=O YROXIXLRRCOBKF-UHFFFAOYSA-N 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/80—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
- B01F27/92—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with helices or screws
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/05—Stirrers
- B01F27/051—Stirrers characterised by their elements, materials or mechanical properties
- B01F27/053—Stirrers characterised by their elements, materials or mechanical properties characterised by their materials
- B01F27/0531—Stirrers characterised by their elements, materials or mechanical properties characterised by their materials with particular surface characteristics, e.g. coated or rough
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/05—Stirrers
- B01F27/07—Stirrers characterised by their mounting on the shaft
- B01F27/073—Stirrers characterised by their mounting on the shaft with stirring elements moving with respect to the stirrer shaft, e.g. floating or comprising contracting chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/05—Stirrers
- B01F27/11—Stirrers characterised by the configuration of the stirrers
- B01F27/114—Helically shaped stirrers, i.e. stirrers comprising a helically shaped band or helically shaped band sections
- B01F27/1141—Helically shaped stirrers, i.e. stirrers comprising a helically shaped band or helically shaped band sections having holes in the surface
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/10—Maintenance of mixers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
- B01F2035/35—Use of other general mechanical engineering elements in mixing devices
- B01F2035/351—Sealings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
- B01F2035/35—Use of other general mechanical engineering elements in mixing devices
- B01F2035/352—Bearings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/22—Mixing of ingredients for pharmaceutical or medical compositions
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mixers Of The Rotary Stirring Type (AREA)
Abstract
The present invention relates to agitating device technical field, especially a kind of tolylsulfonylurea production agitating device, including casing, box house is fixedly connected with rotating shaft, sleeve pipe is coaxially connected with outside rotating shaft, auger leaf is fixedly connected with sleeve outer wall, some sliding blocks are equidistantly connected with rotating shaft outer wall vertically, internal surface of sleeve pipe corresponding position is provided with chute, two baffle plates are symmetrically connected with chute inwall, two installation rooms are arranged with chute, baffle plate is symmetrically connected with some montants close on the side of installation room, and connecting plate is fixedly connected with montant, spring is fixedly connected with connecting plate, rotating shaft one end extends to outside casing and is fixedly connected with motor, motor is fixedly connected on casing, the rotating shaft other end is threaded with closure, casing top connection is provided with charging aperture, connection is provided with discharging opening below wall box.Dismountable auger leaf that the present invention is set can be good at being stirred raw material, improve the quality produced after mixing.
Description
Technical field
The present invention relates to agitating device technical field, more particularly to a kind of tolylsulfonylurea production agitating device.
Background technology
The existing diabetic in the whole world can be stepped up more than 1.5 hundred million, and China now there are about 5,000 ten thousand diabetics
Occupy second place of the world.Clinical conventional OHA mainly has alpha-glucosidase restrainer, sulfonamides and biguanides at present
Etc. several classes, wherein sulfonylurea hypoglycemic agent is most widely used one kind.Gliclazide, orinase are domestic and international hypoglycemic masters
Medicine is flowed, dosage is big, and domestic major medicine manufacture has production, and tolylsulfonylurea is as gliclazide, orinase
The intermediate of production, dosage progressively rise, and supply falls short of demand for product, and market prospects are very wide, therefore the synthesis of tolylsulfonylurea
Technique is paid attention to by various countries., it is necessary to which raw material is carried out into mixing processing, existing skill during tolylsulfonylurea is synthesized
Many agitating devices, which all exist, in art stirs the shortcomings that uneven, while stirring structure is inconvenient to dismantle, to safeguarding and changing
Very big puzzlement is all caused, so not only production efficiency is low, and reduces the quality of production.
The content of the invention
The invention aims to solve shortcoming present in prior art, and a kind of tolylsulfonylurea proposed is given birth to
Production agitating device.
To achieve these goals, present invention employs following technical scheme：
A kind of tolylsulfonylurea production agitating device is designed, including casing, the box house are fixedly connected with rotating shaft, institute
State and be coaxially connected with sleeve pipe outside rotating shaft, be fixedly connected with auger leaf on described sleeve pipe outer wall, along axle on the rotating shaft outer wall
To some sliding blocks are equidistantly connected with, described sleeve pipe inwall corresponding position is provided with chute, and the sliding block is located in chute, the cunning
Two baffle plates are symmetrically connected with groove inwall, the sliding block is arranged with two peaces between two baffle plates on the chute
Room is filled, the baffle plate is symmetrically connected with some montants close on the side of installation room, and the montant extends to installation interior, and institute
State and connecting plate is fixedly connected with montant, spring is fixedly connected with the connecting plate, the spring other end is fixedly connected on
Install in chamber interior walls, the spring is located on montant, and described rotating shaft one end extends to outside casing and is fixedly connected with motor, described
Motor is fixedly connected on casing, and the rotating shaft other end is threaded with closure, and it is straight that the closure diameter is more than sleeve pipe
Footpath, the casing top connection are provided with charging aperture, are connected below the wall box and be provided with discharging opening.
Preferably, the casing top is fixedly connected with motor room, and the motor base is fixedly connected in motor room.
Preferably, the auger leaf includes fixed frame, and the fixed frame is fixedly connected on sleeve pipe, the fixed frame
In the shape of a spiral, it is fixedly connected with screen cloth in the fixed frame, on the fixed frame, screen cloth, rotating shaft, closure and cabinet wall
Provided with erosion shield.
Preferably, the rotating shaft is fixedly connected by sealed bearings with casing top.
Preferably, the bottom half corner is provided with and is equipped with base.
A kind of tolylsulfonylurea production agitating device proposed by the present invention, beneficial effect are：What the present invention was set
Dismountable auger leaf can facilitate the demolition and maintenance to device, while the cooperation of the baffle plate and spring etc. set, can
The sleeve pipe for being provided with auger leaf is played a part of laterally buffering when rotated, can stir spiral under the action of the spring
Mix leaf and produce horizontal movement, be advantageous to the uniform stirring to raw material.
Brief description of the drawings
Fig. 1 is a kind of structural representation of tolylsulfonylurea production agitating device proposed by the present invention.
Fig. 2 is rotating shaft and the connection figure of sleeve pipe of a kind of tolylsulfonylurea production agitating device proposed by the present invention.
Fig. 3 is a kind of A of tolylsulfonylurea production agitating device partial enlarged drawing proposed by the present invention.
Fig. 4 is rotation paddle and the connection of sleeve pipe of a kind of tolylsulfonylurea production agitating device proposed by the present invention
Figure.
In figure：Charging aperture 1, motor 2, motor room 3, sealed bearings 4, auger leaf 5, casing 6, discharging opening 7, closure
8th, rotating shaft 9, sleeve pipe 10, sliding block 11, installation room 12, chute 13, baffle plate 14, montant 15, connecting plate 16, spring 17, screen cloth 18, solid
Determine frame 19, base 20.
Embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation describes, it is clear that described embodiment is only part of the embodiment of the present invention, rather than whole embodiments.
Reference picture 1-4, a kind of tolylsulfonylurea production agitating device, including casing 6, the bottom four corners of casing 6 are provided with
Base 20 is equipped with, rotating shaft 9 is fixedly connected with inside casing 6, sleeve pipe 10 is coaxially connected with outside rotating shaft 9, is consolidated on the outer wall of sleeve pipe 10
Surely auger leaf 5 is connected with, auger leaf 5 includes fixed frame 19, and fixed frame 19 is fixedly connected on sleeve pipe 10, fixed frame
19 in the shape of a spiral, is fixedly connected with screen cloth 18 in fixed frame 19, and the setting of screen cloth 18 makes raw material can be from during stirring
Spilt in screen cloth 18, be stirred raw material more uniform, improve the quality of production.
Some sliding blocks 11 are equidistantly connected with the outer wall of rotating shaft 9 vertically, the inwall corresponding position of sleeve pipe 10 is provided with chute 13,
Sliding block 11 is located in chute 13, and two baffle plates 14 are symmetrically connected with the inwall of chute 13, and sliding block 11 is located between two baffle plates 14,
Two installation rooms 12 are arranged with chute 13, baffle plate 14 is symmetrically connected with some montants 15 close on the side of installation room 12,
Montant 15 is extended in installation room 12, and connecting plate 16 is fixedly connected with montant 15, and spring is fixedly connected with connecting plate 16
17, the other end of spring 17 is fixedly connected on the installation inwall of room 12, and spring 17 is located on montant 15, and rotating shaft 9 drives when rotated
Sliding block 11 moves in chute 13, in the presence of spring 17 and baffle plate 14, can laterally produce movement, drive auger leaf 5
It is mobile, the speed of the stirring of quickening, and then improve the quality of production.
The one end of rotating shaft 9 extends to the outside of casing 6 and is fixedly connected with motor 2, and motor 2 is fixed by wire and electric supply installation to be connected
Connect, rotating shaft 9 is fixedly connected by sealed bearings 4 with the top of casing 6, and motor 2 is fixedly connected on casing 6, and the top of casing 6 is fixed
Motor room 3 is connected with, the base of motor 2 is fixedly connected in motor room 3, and the other end of rotating shaft 9 is threaded with closure 8, sealing
The diameter of lid 8 is more than the diameter of sleeve pipe 10, and the connection of the top of casing 6 is provided with charging aperture 1, is connected below the side wall of casing 6 and be provided with discharging opening 7,
Erosion shield is equipped with fixed frame 19, screen cloth 18, rotating shaft 9, closure 8 and the inwall of casing 6, is prevented rotten by the raw material of inside
Erosion, extends the service life of device, and dismountable structure has been also convenient for the disassembly and installation to device.
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto,
Any one skilled in the art the invention discloses technical scope in, technique according to the invention scheme and its
Inventive concept is subject to equivalent substitution or change, should all be included within the scope of the present invention.
Claims (5)
1. a kind of tolylsulfonylurea production agitating device, including casing（6）, the casing（6）Inside, which is fixedly connected with, to be turned
Axle（9）, it is characterised in that the rotating shaft（9）It is coaxially connected with sleeve pipe outside（10）, described sleeve pipe（10）It is fixedly connected with outer wall
Auger leaf（5）, the rotating shaft（9）Some sliding blocks are equidistantly connected with outer wall vertically（11）, described sleeve pipe（10）Inwall
Corresponding position is provided with chute（13）, the sliding block（11）Positioned at chute（13）It is interior, the chute（13）Symmetrically connected on inwall
There are two baffle plates（14）, the sliding block（11）Positioned at two baffle plates（14）Between, the chute（13）On be arranged with two peaces
Fill room（12）, the baffle plate（14）Close to installation room（12）Side on be symmetrically connected with some montants（15）, the montant
（15）Extend to installation room（12）It is interior, and the montant（15）On be fixedly connected with connecting plate（16）, the connecting plate（16）On
It is fixedly connected with spring（17）, the spring（17）The other end is fixedly connected on installation room（12）On inwall, the spring（17）
Positioned at montant（15）On, the rotating shaft（9）One end extends to casing（6）Outside and motor（2）It is fixedly connected, the motor（2）
It is fixedly connected on casing（6）On, the rotating shaft（9）The other end is threaded with closure（8）, the closure（8）Diameter is big
In sleeve pipe（10）Diameter, the casing（6）Top connection is provided with charging aperture（1）, the casing（6）Connection is provided with out below side wall
Material mouth（7）.
A kind of 2. tolylsulfonylurea production agitating device according to claim 1, it is characterised in that the casing
（6）Top is fixedly connected with motor room（3）, the motor（2）Base is fixedly connected on motor room（3）It is interior.
3. a kind of tolylsulfonylurea production agitating device according to claim 1, it is characterised in that the spiral stirs
Mix leaf（5）Including fixed frame（19）, the fixed frame（19）It is fixedly connected on sleeve pipe（10）On, the fixed frame（19）Helically
Shape, the fixed frame（19）Inside it is fixedly connected with screen cloth（18）, the fixed frame（19）, screen cloth（18）, rotating shaft（9）, closure
（8）And casing（6）Erosion shield is equipped with inwall.
A kind of 4. tolylsulfonylurea production agitating device according to claim 1, it is characterised in that the rotating shaft
（9）Pass through sealed bearings（4）And casing（6）Top is fixedly connected.
A kind of 5. tolylsulfonylurea production agitating device according to claim 1, it is characterised in that the casing
（6）Bottom four corners are provided with and are equipped with base（20）.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711250461.4A CN107790037A (en) | 2017-12-01 | 2017-12-01 | A kind of tolylsulfonylurea production agitating device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711250461.4A CN107790037A (en) | 2017-12-01 | 2017-12-01 | A kind of tolylsulfonylurea production agitating device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107790037A true CN107790037A (en) | 2018-03-13 |
Family
ID=61536903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711250461.4A Pending CN107790037A (en) | 2017-12-01 | 2017-12-01 | A kind of tolylsulfonylurea production agitating device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107790037A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019185234A1 (en) * | 2018-03-24 | 2019-10-03 | Siempelkamp Maschinen- Und Anlagenbau Gmbh | Mixer system |
| WO2019185236A1 (en) * | 2018-03-24 | 2019-10-03 | Siempelkamp Maschinen- Und Anlagenbau Gmbh | Mixing device for fibres or chips and a binder |
| WO2019185235A1 (en) * | 2018-03-24 | 2019-10-03 | Siempelkamp Maschinen- Und Anlagenbau Gmbh | Mixing device for fibres or chips and a binder |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB184433A (en) * | 1921-03-01 | 1922-08-01 | Charles Edward Gardner | Improvements in and connected with mixing and/or disintegrating machines |
| CN104924456A (en) * | 2015-06-25 | 2015-09-23 | 陆丽曼 | Vertical efficient mixer for ceramic production |
| CN206391959U (en) * | 2017-01-14 | 2017-08-11 | 营山县智达能源生态环保研究所 | A kind of compound material mixer |
| CN206454576U (en) * | 2016-12-20 | 2017-09-01 | 自贡市锋锐新材料有限公司 | A kind of well-mixed carborundum wet-milling mixing device |
| CN207856784U (en) * | 2017-12-01 | 2018-09-14 | 响水台舍化工有限公司 | A kind of tolylsulfonylurea production agitating device |
-
2017
- 2017-12-01 CN CN201711250461.4A patent/CN107790037A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB184433A (en) * | 1921-03-01 | 1922-08-01 | Charles Edward Gardner | Improvements in and connected with mixing and/or disintegrating machines |
| CN104924456A (en) * | 2015-06-25 | 2015-09-23 | 陆丽曼 | Vertical efficient mixer for ceramic production |
| CN206454576U (en) * | 2016-12-20 | 2017-09-01 | 自贡市锋锐新材料有限公司 | A kind of well-mixed carborundum wet-milling mixing device |
| CN206391959U (en) * | 2017-01-14 | 2017-08-11 | 营山县智达能源生态环保研究所 | A kind of compound material mixer |
| CN207856784U (en) * | 2017-12-01 | 2018-09-14 | 响水台舍化工有限公司 | A kind of tolylsulfonylurea production agitating device |
Non-Patent Citations (1)
| Title |
|---|
| 顾芳珍等: "《化工设备设计基础》", 天津大学出版社, pages: 193 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019185234A1 (en) * | 2018-03-24 | 2019-10-03 | Siempelkamp Maschinen- Und Anlagenbau Gmbh | Mixer system |
| WO2019185236A1 (en) * | 2018-03-24 | 2019-10-03 | Siempelkamp Maschinen- Und Anlagenbau Gmbh | Mixing device for fibres or chips and a binder |
| WO2019185235A1 (en) * | 2018-03-24 | 2019-10-03 | Siempelkamp Maschinen- Und Anlagenbau Gmbh | Mixing device for fibres or chips and a binder |
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| PB01 | Publication | ||
| PB01 | Publication | ||
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Application publication date: 20180313 |