CN107782702A - A kind of haemocyte detector of high reliability - Google Patents
A kind of haemocyte detector of high reliability Download PDFInfo
- Publication number
- CN107782702A CN107782702A CN201610788343.8A CN201610788343A CN107782702A CN 107782702 A CN107782702 A CN 107782702A CN 201610788343 A CN201610788343 A CN 201610788343A CN 107782702 A CN107782702 A CN 107782702A
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- Prior art keywords
- high reliability
- haemocyte
- module
- adjustment
- reception signal
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/59—Transmissivity
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N2021/8405—Application to two-phase or mixed materials, e.g. gas dissolved in liquids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/12—Circuits of general importance; Signal processing
- G01N2201/126—Microprocessor processing
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention discloses a kind of haemocyte detector of high reliability,It is related to medical instruments field,Including hardware components and software section,The hardware components are by microcontroller,Luminous tube drive circuit,Infraluminescence pipe,Infrared receiving tube,Reception signal amplifying circuit,Adjustment of sensitivity device forms,The microprocessor connects and controls adjustment of sensitivity device and luminous tube drive circuit,The luminous tube drive circuit,Infraluminescence pipe,Infrared receiving tube and reception signal amplifying circuit are electrically connected with successively,The reception signal amplifying circuit is connected with microprocessor again,The integrated height of hardware circuit device of the present invention,Good reliability,Anti- bubble interference performance is strong,Small volume,Low cost and other advantages,Simultaneously,With POST function,Luminous intensity automatic calibration function,Adjustment of sensitivity function,Enabled control function,Pipeline installment state arbitration functions and high reliability haemocyte determination methods.
Description
Technical field
The present invention relates to medical instruments field, the haemocyte detector of more particularly to a kind of high reliability.
Background technology
Blood plasma is the important component in blood of human body, and the main purpose for gathering blood plasma is the required biology of preparation medical treatment
Blood used in clinic slurry needed for product and component blood transfusion, and if there is excessive blood cell composition in blood plasma during Plasma Pheresis/Apheresis Plasma,
Follow-up preparation process will be caused to perplex or risk is caused to clinical infusion blood plasma, so, to blood during collection blood plasma
The control of cell is particularly important.When gathering blood plasma process, being mixed into excessive blood cell composition in collection blood plasma to prevent needs
To be detected by haemocyte detector, be for common practice in the control technology industry of haemocyte detector：A. hardware
Aspect：Haemocyte detector is only responsible for output analog voltage signal, and without arbitration functions, arbitration functions are typically integrated in blood
In the master control program of component collection equipment.B. software aspects：On the basis of the parameter of certain point, real-time parameter and benchmark are joined
Number is compared, and when the size or amplitude of calculating difference meet predetermined size or amplitude, is judged as haemocyte.
The problem of presently, there are, hardware circuit is complicated, and reliability is poor, the inadequate section of haemocyte determination methods in software
Learn, haemocyte detection often occur and unsuccessfully cause to be mixed into excessive haemocyte in blood plasma, haemocyte detector mistake also often occur
Bubble in blood plasma is judged as to the situation of haemocyte.
The content of the invention
The technical problems to be solved by the invention are to provide a kind of haemocyte detector of high reliability, to solve existing skill
Caused above-mentioned multinomial defect in art.
To achieve the above object, the present invention provides following technical scheme：A kind of haemocyte detector of high reliability, bag
Include hardware components and software section, the hardware components by microcontroller, luminous tube drive circuit, infraluminescence pipe, infrared connect
Closed tube, reception signal amplifying circuit, adjustment of sensitivity device composition, the microprocessor connect and have controlled sensitivity controller
Part and luminous tube drive circuit, the luminous tube drive circuit are electrically connected with infraluminescence pipe, infrared receiving tube and connect successively
Signal amplification circuit is received, the reception signal amplifying circuit is connected with microprocessor again.
Preferably, the microcontroller is used with AD conversion, DA conversions, internal clocking, internal reset, I/O mouth multimodes
The small size paster of formula output function encapsulates 51 single-chip microcomputers, DSP Processor or arm processor.
Preferably, the adjustment of sensitivity device is using binary-coded decimal switch, potentiometer or toggle switch.
Preferably, the software section is by enabled input module, DA shift control modules, AD conversion control module, energization
Selftest module, sampling parameter processing module and haemocyte judge and signal output module is sequentially connected composition.
Preferably, the AD conversion control module, which is provided with, is sequentially connected the automatic calibration module of luminous intensity and pipeline installation shape
State judges and output module, and pipeline installment state judges and output module is connected with DA shift control modules again.
Beneficial effect using above technical scheme is：The haemocyte detector of structure high reliability of the present invention, hardware electricity
The integrated height of road device, good reliability, anti-bubble interference performance are strong, small volume, low cost and other advantages, meanwhile, have and be powered certainly
Checking functions, luminous intensity automatic calibration function, adjustment of sensitivity function, enabled control function, pipeline installment state arbitration functions and
High reliability haemocyte determination methods.
Brief description of the drawings
Fig. 1 is the structured flowchart of the haemocyte detector hardware components of high reliability of the present invention.
Fig. 2 is the structured flowchart of the haemocyte detector software section of high reliability of the present invention.
Wherein, 1- microcontrollers, 2- light tube drive circuit, 3- infraluminescence pipes, 4- infrared receiving tubes, 5- reception signals
Amplifying circuit, 6- adjustment of sensitivity devices, 7- enable input module, 8-DA shift control modules, 9-AD shift control modules,
10- power-on self-test modules, 11- luminous intensity automatic converting modules, 12- pipelines installment state judges and output module, 13- sampling ginsengs
Number processing module, 14- haemocytes judge and signal output module.
Embodiment
The preferred embodiment of the haemocyte detector for high reliability that the invention will now be described in detail with reference to the accompanying drawings.
Fig. 1 and Fig. 2 shows the embodiment of the haemocyte detector of high reliability of the present invention：A kind of high reliability
Haemocyte detector, including hardware components and software section.The hardware components by microcontroller 1, luminous tube drive circuit 2,
Infraluminescence pipe 3, infrared receiving tube 4, reception signal amplifying circuit 5, adjustment of sensitivity device 6 form.The DA of microcontroller 1 turns
The drive circuit that output pin is changed with infraluminescence pipe circuit 2 is connected, and luminous tube drive circuit 2 is connected with infraluminescence pipe 3, red
Outer luminous tube 3 passes to infrared receiving tube 4, infrared receiving tube 4 and reception signal amplification electricity after detecting the data of plasma tube
Road 5 is connected, and reception signal amplification electricity 5 is connected with the AD conversion input pin of microcontroller 1, adjustment of sensitivity device 6 and micro-control
Device 1I/O pins processed are connected, and microcontroller 1I/O pins are with open collector pattern output haemocyte detection status signal and pipeline
Installment state signal, the enabled control input signal in outside are directly inputted to the external interrupt pin of microcontroller 1.
In the present embodiment, the microcontroller 1 is using with AD conversion, DA conversions, internal clocking, internal reset, I/O
The small size paster of mouth multi-mode output function encapsulates 51 single-chip microcomputers, DSP Processor or arm processor etc..
In the present embodiment, the adjustment of sensitivity device 6 is using binary-coded decimal switch, potentiometer or toggle switch etc..
In the present embodiment, software section is included in microcontroller 1, the software section is turned by enabled input module 7, DA
Control module 8, AD conversion control module 9, power-on self-test module 10, sampling parameter processing module 13 and haemocyte is changed to judge and believe
Number output module 14 is sequentially connected composition.
In the present embodiment, the AD conversion control module 9, which is provided with, is sequentially connected the automatic He of calibration module 11 of luminous intensity
Pipeline installment state judge and output module 12, pipeline installment state judge and output module 12 again with DA shift control modules 8
It is connected.
The processing sequence of software section is followed successively by：DA shift control modules 8, AD conversion control module 9, power-on self-test module
10th, the automatic calibration module 11 of luminous intensity, sampling parameter processing module 13, haemocyte judgement and signal output module 14, pipeline peace
Condition adjudgement and output module 12 are filled, it is highest priority interrupt service routine to enable input module 7.
The operation principle of the haemocyte detector of high reliability of the present invention is as follows：Microcontroller 1 passes through its DA translation function
Output analog voltage signal is connected on infraluminescence pipe 3 through luminous tube drive circuit, and the infrared light that infraluminescence pipe 3 is sent is saturating
Cross detected material (generally PVC conduits and blood plasma or haemocyte) to be radiated on infrared receiving tube 4, infrared receiving tube 4 will receive
To infrared signal be converted to electric signal and be connected to reception signal amplifying circuit 5, the analog voltage signal input after amplification
To the AD conversion functional pin of microcontroller 1, analog voltage signal is converted to numeral by microcontroller 1 by its AD conversion function
Signal, obtained data signal is subjected to logical operation and processing, filters out bubble interference data, obtain the translucency of detected material
Curve, printing opacity linearity curve is judged further according to the setting state of adjustment of sensitivity device 6, when printing opacity linearity curve meet it is sensitive
When spending the curvilinear characteristic set by adjusting means, it is judged as haemocyte, state output signal is overturn, and is otherwise judged as bubble
Or blood plasma, do not process.
Based on above-mentioned, the haemocyte detector of structure high reliability of the present invention, the integrated height of hardware circuit device, reliability
Good, anti-bubble interference performance is strong, small volume, low cost and other advantages, meanwhile, there is POST function, luminous intensity to calibrate automatically
Function, adjustment of sensitivity function, enabled control function, pipeline installment state arbitration functions and high reliability haemocyte judgement side
Method.
Above-described is only the preferred embodiment of the present invention, it is noted that for one of ordinary skill in the art
For, without departing from the concept of the premise of the invention, various modifications and improvements can be made, these belong to the present invention
Protection domain.
Claims (5)
1. a kind of haemocyte detector of high reliability, including hardware components and software section, it is characterised in that：The Hardware Subdivision
Divide by microcontroller, luminous tube drive circuit, infraluminescence pipe, infrared receiving tube, reception signal amplifying circuit, adjustment of sensitivity
Device forms, and the microprocessor connects and controlled adjustment of sensitivity device and luminous tube drive circuit, and the luminous tube drives
Dynamic circuit is electrically connected with infraluminescence pipe, infrared receiving tube and reception signal amplifying circuit, the reception signal amplification successively
Circuit is connected with microprocessor again.
2. the haemocyte detector of a kind of high reliability according to claim 1, it is characterised in that the microcontroller is adopted
It is single with the small size paster encapsulation 51 with AD conversion, DA conversions, internal clocking, internal reset, I/O mouth multi-mode output functions
Piece machine, DSP Processor or arm processor.
A kind of 3. haemocyte detector of high reliability according to claim 1, it is characterised in that the adjustment of sensitivity
Device is using binary-coded decimal switch, potentiometer or toggle switch.
A kind of 4. haemocyte detector of high reliability according to claim 1, it is characterised in that the software section by
Enabled input module, DA shift control modules, AD conversion control module, power-on self-test module, sampling parameter processing module and blood
Cell judges and signal output module is sequentially connected composition.
A kind of 5. haemocyte detector of high reliability according to claim 4, it is characterised in that the AD conversion control
Module, which is provided with, is sequentially connected the automatic calibration module of luminous intensity and the judgement of pipeline installment state and output module, pipeline installment state
Judge and output module is connected with DA shift control modules again.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610788343.8A CN107782702A (en) | 2016-08-31 | 2016-08-31 | A kind of haemocyte detector of high reliability |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610788343.8A CN107782702A (en) | 2016-08-31 | 2016-08-31 | A kind of haemocyte detector of high reliability |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107782702A true CN107782702A (en) | 2018-03-09 |
Family
ID=61451419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610788343.8A Pending CN107782702A (en) | 2016-08-31 | 2016-08-31 | A kind of haemocyte detector of high reliability |
Country Status (1)
| Country | Link |
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| CN (1) | CN107782702A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023019611A1 (en) * | 2021-08-16 | 2023-02-23 | 赛若麦得（上海）生物技术有限公司 | High-reliability cell detector |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130334420A1 (en) * | 2012-06-15 | 2013-12-19 | Fenwal, Inc. | Process for Predicting Hematocrit of Whole Blood Using IR Light |
| CN203365333U (en) * | 2013-07-12 | 2013-12-25 | 杜铁军 | Red blood cell detector |
| CN204086121U (en) * | 2013-12-13 | 2015-01-07 | 周冀馨 | A kind of blood test device |
-
2016
- 2016-08-31 CN CN201610788343.8A patent/CN107782702A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130334420A1 (en) * | 2012-06-15 | 2013-12-19 | Fenwal, Inc. | Process for Predicting Hematocrit of Whole Blood Using IR Light |
| CN203365333U (en) * | 2013-07-12 | 2013-12-25 | 杜铁军 | Red blood cell detector |
| CN204086121U (en) * | 2013-12-13 | 2015-01-07 | 周冀馨 | A kind of blood test device |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023019611A1 (en) * | 2021-08-16 | 2023-02-23 | 赛若麦得（上海）生物技术有限公司 | High-reliability cell detector |
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