CN107778272B - A kind of method and apparatus producing hemiacetal using alcohol dehydrogenase - Google Patents

A kind of method and apparatus producing hemiacetal using alcohol dehydrogenase Download PDF

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CN107778272B
CN107778272B CN201711066105.7A CN201711066105A CN107778272B CN 107778272 B CN107778272 B CN 107778272B CN 201711066105 A CN201711066105 A CN 201711066105A CN 107778272 B CN107778272 B CN 107778272B
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gas
absorption tower
guide tube
water tank
pipe
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CN107778272A (en
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王建玲
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Jiangxi far State Pharmaceutical Co., Ltd.
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Jiangxi Far State Pharmaceutical Co Ltd
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/28Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/32Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with molecular oxygen
    • C07C45/37Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with molecular oxygen of >C—O—functional groups to >C=O groups
    • C07C45/38Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with molecular oxygen of >C—O—functional groups to >C=O groups being a primary hydroxyl group

Abstract

The invention discloses a kind of method and devices producing hemiacetal using alcohol dehydrogenase, by using rational production stage and process units, raw polyol, steam and air are formed into mixed gas, it is evaporated and is sent into oxidation reactor using evaporator and be oxidized to gaseous aldehyde by the catalytic action of catalyst, by cooling and absorption, to obtain hemiacetal.In hemiacetal produces preparation process, production efficiency obtains larger raising, and heat is adequately recycled, at the same the gases such as hydrogen generated it is burned after discharge, reduce the pollution to environment, be suitble to be widely popularized, be conducive to the sustainable development of economic society.

Description

A kind of method and apparatus producing hemiacetal using alcohol dehydrogenase
Technical field
The present invention relates to hemiacetal production technical fields, and more specifically more particularly to a kind of utilization alcohol dehydrogenase produces half The method and apparatus of acetal.
Background technology
Hemiacetal(hemiacetal), the hydrate RCH of aldehyde(OH)The RCH that the alcohol R ' OH of 2 and 2 molecules are combined with ehter bond (OR′)2 are known as acetal(acetal), the RCH that is combined with a molecule alcohol(OH)OR ' is known as hemiacetal(Hemia-cetal or hemiacetal).Aldehyde is the compound for being connected with aldehyde radical by alkyl and being constituted, and is abbreviated as RCHO.Aldehyde(English:aldehyde)Belong to It is aldehyde radical (- CHO) and alkyl in organic compound(Or hydrogen atom)The compound being formed by connecting.Aldehyde radical is by carbon atom, one A hydrogen atom and a double bond oxygen atom composition.Aldehyde radical is also referred to as formoxyl.Aldehyde(Qu á n, aldehyde):Organic compound One kind is aldehyde radical (- CHO) and alkyl(Or hydrogen atom)The compound being formed by connecting.Aldehyde radical is by a carbon atom, a hydrogen original Son and a double bond oxygen atom composition.Aldehyde radical is also referred to as formoxyl, and aldehyde has very high reactivity, takes part in numerous reactions. From the point of view of industrial point of view, most of important reaction is condensation reaction, such as:Prepare plasticizer and polyol, reduction instead Alcohol should be prepared(Especially carbonyl alcohols).From biological angle, important reaction includes mainly:Prepare the reaction of imines, i.e. formoxyl Nucleophilic addition, such as:Amine reaction, hemiacetal structure are gone in oxidation(Aldose).
Hemiacetal is a kind of important raw material of industry.The method low production efficiency of traditional production hemiacetal, energy consumption is high, contaminates Dirty environment is unfavorable for the sustainable development of society.
Invention content
The purpose of the present invention is to provide a kind of method and apparatus producing hemiacetal using alcohol dehydrogenase, to solve the above-mentioned back of the body The problem of being proposed in scape technology improves the efficiency of production hemiacetal, reduces the energy consumption in production process, reduces the dirt to environment Dye, to push sustainable development.
To achieve the above object, the present invention provides the following technical solutions:A method of hemiacetal being produced using alcohol dehydrogenase, It is as follows:
S1:By raw polyol by being sent to mixing chamber after the first material pump and first filter filtering totally;
S2:Water filling in water tank, is heated by heater, and the steam of generation enters mixing by second pipe Room;
S3:Pressure fan starts, and air is sent into mixing chamber by blast pipe after the filtering of the second filter is clean;
S4:The material that S1, S2 and S3 are sent into flashes to mixed gas by mixing indoor evaporator, and mixed gas enters First gas-guide tube is passed through by being entered in oxidation reactor after spark arrester and the filtering of third filter in oxidation reactor The catalytic action of catalyst is oxidized to gaseous aldehyde;
S5:Gaseous aldehyde is entered by the second gas-guide tube in cooling water tank, and the second gas-guide tube in cooling water tank is S-type, It can fully improve the time of contact of water in the second gas-guide tube and cooling water tank, ensure heat recovery effect;
S6:Gas after cooling enters in cooler bin in S5, and cooling soft water is added in cooler bin in advance, carries out cold again But;
S7:Mixed gas after cooling is entered by third gas-guide tube in the first absorption tower, by aldehyde in the first absorption tower Class gas absorbs, and unabsorbed gases, which enters back into second absorption tower, to be continued to be absorbed;
S8:The tail gas come out by second absorption tower is entered in burning boiler by pipeline by exhaust combustion, in boiler The vapor that room generates that is filled with water, which is entered by return duct in second pipe, to be continued with, other gases pass through exhaust in the combustion chamber Pipe and the discharge of the 4th filter;
S9:Absorbing liquid in second absorption tower is pumped by the second material, liquid is sent into the first absorption tower, collected first and inhale The liquid in tower is received, aldehydes or hemiacetal liquid are obtained;
S10:By the liquid meter obtained in S9 and packs and store.
Preferably, it is described it is a kind of using alcohol dehydrogenase produce hemiacetal method use device include material box, water tank and Mixing chamber, the material box are communicated in mixing chamber by first pipe, and the first pipe is equipped with the first material pump and the first mistake Filter, installs having heaters in the water tank, and the water tank is communicated in mixing chamber by second pipe, side on the mixing chamber It is also communicated with blast pipe, pressure fan and the second filter are installed on the blast pipe, evaporator is installed in the mixing chamber, The mixing chamber side is connected with the first gas-guide tube, and first gas-guide tube side is communicated with oxidation reactor, and described first leads Spark arrester and third filter are installed, the oxidation reactor side is connected with the second gas-guide tube, and described second leads on tracheae Through having cooling water tank, the cooling water tank side to be equipped with cooler bin, second gas-guide tube is communicated in cooler bin for tracheae side, The cooler bin side is communicated with the first absorption tower by third gas-guide tube, and first absorption tower is connected to by the 4th gas-guide tube There is second absorption tower, the second absorption tower bottom is communicated in the first absorption tower by pipeline, and the second material is equipped on pipeline Pump, the second absorption tower side is communicated with burning boiler by pipeline, return duct is connected at the top of the burning boiler, described Return duct is communicated in second pipe.
Preferably, the second gas-guide tube arrangement mode in the cooling water tank is S-type.
Preferably, the alcohol is dihydric alcohol.
Preferably, the alcohol is butanediol or hexylene glycol.
Preferably, second gas-guide tube and cooling water tank are equipped with sealing ring through position.
Preferably, the material box, water tank, cooling water tank and cooler bin upper top offer import, and are set in import There is sealing cover.
Preferably, the burning boiler includes combustion chamber and the room that is filled with water, and combustor side is connected with exhaust pipe, the row Tracheae is equipped with the 4th filter.
Preferably, the return duct is connected to second pipe by three-way connection.
Preferably, in order to improve the production efficiency of hemiacetal, in step s 2, the heating temperature of the heater is T(It is single Position is degree Celsius), the steam of generation is P in the pressure of mixing chamber(Unit is megapascal), the heating temperature T and steam are mixing The pressure of room is that P meets following relationship:
P=αT;
Wherein α is product coefficient, when the product of production is aldehyde, α 2.3-4.2;When the product of production is hemiacetal, α is 1.5-2.5.
Compared with prior art, the beneficial effects of the invention are as follows:
(1)A kind of method producing hemiacetal using alcohol dehydrogenase of the present invention, improves the efficiency of production hemiacetal, reduction pair The pollution of environment.
(2)A kind of method producing hemiacetal using alcohol dehydrogenase of the present invention, it is mixed by forming raw polyol, steam and air Close gas, evaporate using evaporator and be sent into oxidation reactor pass through catalyst catalytic action be oxidized to gaseous aldehyde, aldehyde Class gas is entered by the second gas-guide tube in cooling water tank, and the second gas-guide tube in cooling water tank is S-type, can fully improve The time of contact of water in two gas-guide tubes and cooling water tank ensures that heat recovery effect, gas after cooling enter in cooler bin, in advance Cooling soft water is first added in cooler bin, is cooled down again, mixed gas after cooling enters first by third gas-guide tube In absorption tower, gaseous aldehyde is absorbed in the first absorption tower, unabsorbed gases, which enters back into, continues quilt in second absorption tower It absorbs, the tail gas come out by second absorption tower is entered in burning boiler by pipeline by exhaust combustion, the room that is filled with water in boiler The vapor of generation, which is entered by return duct in second pipe, to be continued with, other gases pass through exhaust pipe and in the combustion chamber Four filters are discharged, and the absorbing liquid in second absorption tower are pumped by the second material, liquid is sent into the first absorption tower, collect first Liquid in absorption tower obtains and contains hemiacetal liquid, and in producing preparation process, heat is adequately recycled, simultaneously It is discharged after the gases such as the hydrogen of generation are burned, is conducive to environment, while the aldehyde material that two absorption towers absorb production is set, Absorption efficiency and assimilation effect are improved, is suitble to be widely popularized.
Description of the drawings
Fig. 1 is schematic structural view of the invention;
Fig. 2 is enlarged structure schematic diagram at A of the present invention.
In figure:1 material box, 2 water tanks, 3 mixing chambers, 4 heaters, 5 first pipes, 6 second pipes, 7 first filters, 8 First material pump, 9 blast pipes, 10 pressure fan, 11 second filters, 12 evaporators, 13 spark arresters, 14 third filters, 15 first Gas-guide tube, 16 oxidation reactors, 17 second gas-guide tubes, 18 cooling water tanks, 19 cooler bins, 20 third gas-guide tubes, 21 first absorb Tower, 22 the 4th gas-guide tubes, 23 second absorption towers, 24 second material pump, 25 burning boilers, 26 return ducts, 27 three-way connections, 28 exhausts Pipe, 29 the 4th filters.
Specific implementation mode
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation describes, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
Embodiment 1:
- 2 are please referred to Fig.1, a method of hemiacetal being produced using alcohol dehydrogenase, is as follows:
S1:By raw polyol by being sent to mixing chamber after the first material pump and first filter filtering totally;
S2:Water filling in water tank is heated by heater 4, and the steam of generation enters mixing by second pipe Room;
S3:Pressure fan starts, and air is sent into mixing chamber by blast pipe after the filtering of the second filter is clean;
S4:The material that S1, S2 and S3 are sent into flashes to mixed gas by mixing indoor evaporator, and mixed gas enters First gas-guide tube is passed through by being entered in oxidation reactor after spark arrester and the filtering of third filter in oxidation reactor The catalytic action of catalyst is oxidized to gaseous aldehyde;
S5:Gaseous aldehyde is entered by the second gas-guide tube in cooling water tank, and the second gas-guide tube in cooling water tank is S-type, It can fully improve the time of contact of water in the second gas-guide tube and cooling water tank, ensure heat recovery effect;
S6:Gas after cooling enters in cooler bin in S5, and cooling soft water is added in cooler bin in advance, carries out cold again But;
S7:Mixed gas after cooling is entered by third gas-guide tube in the first absorption tower, by aldehyde in the first absorption tower Class gas absorbs, and unabsorbed gases, which enters back into second absorption tower, to be continued to be absorbed;
S8:The tail gas come out by second absorption tower is entered in burning boiler by pipeline by exhaust combustion, in boiler The vapor that room generates that is filled with water, which is entered by return duct in second pipe, to be continued with, other gases pass through exhaust in the combustion chamber Pipe and the discharge of the 4th filter;
S9:Absorbing liquid in second absorption tower is pumped by the second material, liquid is sent into the first absorption tower, collected first and inhale The liquid in tower is received, the liquid containing hemiacetal is obtained;
S10:By the liquid meter obtained in S9 and packs and store.
The device that a kind of method producing hemiacetal using alcohol dehydrogenase uses includes material box 1, water tank 2 and mixes Room 3 is closed, the material box 1 is communicated in mixing chamber 3 by first pipe 5, and the first pipe 5 is equipped with the first material pump 28 and the One filter 7, the water tank 2 is interior to install having heaters 4, and the water tank 2 is communicated in mixing chamber 3 by second pipe 6, described mixed It closes side on room 3 and is also communicated with blast pipe 9, pressure fan 10 and the second filter 11, the mixing are installed on the blast pipe 9 Evaporator 12 is installed, 3 side of the mixing chamber is connected with the first gas-guide tube 15, and 15 side of the first gas-guide tube connects in room 3 It is connected with oxidation reactor 16, spark arrester 13 and third filter 14, the oxidation reaction are installed on first gas-guide tube 15 16 side of device is connected with the second gas-guide tube 17, and 17 side of the second gas-guide tube, which is run through, cooling water tank 18, the cooling water tank 18 sides are equipped with cooler bin 19, and second gas-guide tube 17 is communicated in cooler bin 19, and 19 side of the cooler bin is led by third Tracheae 20 is communicated with the first absorption tower 21, and first absorption tower 21 is communicated with second absorption tower 23 by the 4th gas-guide tube 22, 23 bottom of the second absorption tower is communicated in the first absorption tower 21 by pipeline, and the second material pump 24 is equipped on pipeline, described 23 side of second absorption tower is communicated with burning boiler 25 by pipeline, and 25 top of the burning boiler is connected with return duct 26, institute It states return duct 26 and is communicated in second pipe 6,17 arrangement mode of the second gas-guide tube in the cooling water tank 18 is S-type, and described Two gas-guide tubes 17 and cooling water tank 18 are equipped with sealing ring, the material box 1, water tank 2, cooling water tank 18 and cooler bin through position 19 upper tops offer import, and import is equipped with sealing cover, and the burning boiler 25 includes combustion chamber and the room that is filled with water, and is fired It burns room side and is connected with exhaust pipe 29, the exhaust pipe 29 is equipped with the 4th filter 30, the return duct 26 and second pipe 6 It is connected to by three-way connection 27.
Embodiment 2:
- 2 are please referred to Fig.1, a method of hemiacetal being produced using alcohol dehydrogenase, is as follows:
S1:By butanediol raw polyol by being sent to mixing chamber after the first material pump and first filter filtering totally;
S2:Water filling in water tank is heated by heater 4, and the steam of generation enters mixing by second pipe Room;
S3:Pressure fan starts, and air is sent into mixing chamber by blast pipe after the filtering of the second filter is clean;
S4:The material that S1, S2 and S3 are sent into flashes to mixed gas by mixing indoor evaporator, and mixed gas enters First gas-guide tube is passed through by being entered in oxidation reactor after spark arrester and the filtering of third filter in oxidation reactor The catalytic action of catalyst is oxidized to gaseous aldehyde;
S5:Gaseous aldehyde is entered by the second gas-guide tube in cooling water tank, and the second gas-guide tube in cooling water tank is S-type, It can fully improve the time of contact of water in the second gas-guide tube and cooling water tank, ensure heat recovery effect;
S6:Gas after cooling enters in cooler bin in S5, and cooling soft water is added in cooler bin in advance, carries out cold again But;
S7:Mixed gas after cooling is entered by third gas-guide tube in the first absorption tower, by aldehyde in the first absorption tower Class gas absorbs, and unabsorbed gases, which enters back into second absorption tower, to be continued to be absorbed;
S8:The tail gas come out by second absorption tower is entered in burning boiler by pipeline by exhaust combustion, in boiler The vapor that room generates that is filled with water, which is entered by return duct in second pipe, to be continued with, other gases pass through exhaust in the combustion chamber Pipe and the discharge of the 4th filter;
S9:Absorbing liquid in second absorption tower is pumped by the second material, liquid is sent into the first absorption tower, collected first and inhale The liquid in tower is received, hemiacetal class I liquid I is obtained;
S10:By the liquid meter obtained in S9 and packs and store.
The device that a kind of method producing hemiacetal using alcohol dehydrogenase uses includes material box 1, water tank 2 and mixes Room 3 is closed, the material box 1 is communicated in mixing chamber 3 by first pipe 5, and the first pipe 5 is equipped with the first material pump 28 and the One filter 7, the water tank 2 is interior to install having heaters 4, and the water tank 2 is communicated in mixing chamber 3 by second pipe 6, described mixed It closes side on room 3 and is also communicated with blast pipe 9, pressure fan 10 and the second filter 11, the mixing are installed on the blast pipe 9 Evaporator 12 is installed, 3 side of the mixing chamber is connected with the first gas-guide tube 15, and 15 side of the first gas-guide tube connects in room 3 It is connected with oxidation reactor 16, spark arrester 13 and third filter 14, the oxidation reaction are installed on first gas-guide tube 15 16 side of device is connected with the second gas-guide tube 17, and 17 side of the second gas-guide tube, which is run through, cooling water tank 18, the cooling water tank 18 sides are equipped with cooler bin 19, and second gas-guide tube 17 is communicated in cooler bin 19, and 19 side of the cooler bin is led by third Tracheae 20 is communicated with the first absorption tower 21, and first absorption tower 21 is communicated with second absorption tower 23 by the 4th gas-guide tube 22, 23 bottom of the second absorption tower is communicated in the first absorption tower 21 by pipeline, and the second material pump 24 is equipped on pipeline, described 23 side of second absorption tower is communicated with burning boiler 25 by pipeline, and 25 top of the burning boiler is connected with return duct 26, institute It states return duct 26 and is communicated in second pipe 6,17 arrangement mode of the second gas-guide tube in the cooling water tank 18 is S-type, and described Two gas-guide tubes 17 and cooling water tank 18 are equipped with sealing ring, the material box 1, water tank 2, cooling water tank 18 and cooler bin through position 19 upper tops offer import, and import is equipped with sealing cover, and the burning boiler 25 includes combustion chamber and the room that is filled with water, and is fired It burns room side and is connected with exhaust pipe 29, the exhaust pipe 29 is equipped with the 4th filter 30, the return duct 26 and second pipe 6 It is connected to by three-way connection 27.
Wherein butanediol passes through two absorption towers under the multifunction catalyst catalysed oxidn of Cu-Zn-Zr-Al-O Absorption obtain and generate hemiacetal, butanediol residual 12%, aldehyde 9%, hemiacetal in end reaction liquid(Dihydroxy furans)79%.
Embodiment 3:
- 2 are please referred to Fig.1, a method of hemiacetal being produced using alcohol dehydrogenase, is as follows:
S1:By butanediol raw material by being sent to mixing chamber after the first material pump and first filter filtering totally;
S2:Water filling in water tank is heated by heater 4, and the steam of generation enters mixing by second pipe Room;The heating temperature of the heater is T(Unit is degree Celsius), the steam of generation is P in the pressure of mixing chamber(Unit is million Pa), the heating temperature T and steam meet following relationship in the pressure of mixing chamber for P:
P=αT;
Wherein α is product coefficient, when the product of production is hemiacetal, α 1.5-2.5.
S3:Pressure fan starts, and air is sent into mixing chamber by blast pipe after the filtering of the second filter is clean;
S4:The material that S1, S2 and S3 are sent into flashes to mixed gas by mixing indoor evaporator, and mixed gas enters First gas-guide tube is passed through by being entered in oxidation reactor after spark arrester and the filtering of third filter in oxidation reactor The catalytic action of catalyst is oxidized to gaseous aldehyde;
S5:Gaseous aldehyde is entered by the second gas-guide tube in cooling water tank, and the second gas-guide tube in cooling water tank is S-type, It can fully improve the time of contact of water in the second gas-guide tube and cooling water tank, ensure heat recovery effect;
S6:Gas after cooling enters in cooler bin in S5, and cooling soft water is added in cooler bin in advance, carries out cold again But;
S7:Mixed gas after cooling is entered by third gas-guide tube in the first absorption tower, by aldehyde in the first absorption tower Class gas absorbs, and unabsorbed gases, which enters back into second absorption tower, to be continued to be absorbed;
S8:The tail gas come out by second absorption tower is entered in burning boiler by pipeline by exhaust combustion, in boiler The vapor that room generates that is filled with water, which is entered by return duct in second pipe, to be continued with, other gases pass through exhaust in the combustion chamber Pipe and the discharge of the 4th filter;
S9:Absorbing liquid in second absorption tower is pumped by the second material, liquid is sent into the first absorption tower, collected first and inhale The liquid in tower is received, obtains and contains hemiacetal class I liquid I;
S10:By the liquid meter obtained in S9 and packs and store.
The device that a kind of method producing hemiacetal using alcohol dehydrogenase uses, including including material box 1,2 and of water tank Mixing chamber 3, the material box 1 are communicated in mixing chamber 3 by first pipe 5, and the first pipe 5 is equipped with the first material and pumps 28 Hes First filter 7, the water tank 2 is interior to install having heaters 4, and the water tank 2 is communicated in mixing chamber 3 by second pipe 6, described Side is also communicated with blast pipe 9 on mixing chamber 3, and pressure fan 10 and the second filter 11 are equipped on the blast pipe 9, described mixed It closes in room 3 and evaporator 12 is installed, 3 side of the mixing chamber is connected with the first gas-guide tube 15,15 side of the first gas-guide tube It is communicated with oxidation reactor 16, spark arrester 13 and third filter 14 are installed on first gas-guide tube 15, the oxidation is anti- 16 side of device is answered to be connected with the second gas-guide tube 17,17 side of the second gas-guide tube, which is run through, cooling water tank 18, the cooling water 18 side of case is equipped with cooler bin 19, and second gas-guide tube 17 is communicated in cooler bin 19, and 19 side of the cooler bin passes through third Gas-guide tube 20 is communicated with the first absorption tower 21, and first absorption tower 21 is communicated with second absorption tower by the 4th gas-guide tube 22 23,23 bottom of the second absorption tower is communicated in the first absorption tower 21 by pipeline, and the second material pump 24, institute are equipped on pipeline It states 23 side of second absorption tower and burning boiler 25 is communicated with by pipeline, 25 top of the burning boiler is connected with return duct 26, The return duct 26 is communicated in second pipe 6, and 17 arrangement mode of the second gas-guide tube in the cooling water tank 18 is S-type, described Second gas-guide tube 17 and cooling water tank 18 are equipped with sealing ring, the material box 1, water tank 2, cooling water tank 18 and cooling through position 19 upper top of case offers import, and import is equipped with sealing cover, and the burning boiler 25 includes combustion chamber and the room that is filled with water, and Combustor side is connected with exhaust pipe 29, and the exhaust pipe 29 is equipped with the 4th filter 30, and the return duct 26 and second is managed Road 6 is connected to by three-way connection 27.
Wherein butanediol passes through two absorption towers under the multifunction catalyst catalysed oxidn of Cu-Zn-Zr-Al-O Absorption obtain and generate hemiacetal, butanediol residual 10%, aldehyde 7%, hemiacetal in end reaction liquid(Dihydroxy furans)83%.
In conclusion a kind of method and apparatus producing hemiacetal using alcohol dehydrogenase of the present invention, by by using reasonable Production stage and process units, by raw polyol, steam and air form mixed gas, evaporated using evaporator and be sent into oxygen Change in reactor and be oxidized to gaseous aldehyde by the catalytic action of catalyst, gaseous aldehyde enters cooling water by the second gas-guide tube In case, the second gas-guide tube in cooling water tank is S-type, can fully improve the second gas-guide tube in cooling water tank when the contact of water Between, ensure that heat recovery effect, gas after cooling enter in cooler bin, cooling soft water is added in cooler bin in advance, carries out It cools down again, mixed gas after cooling is entered by third gas-guide tube in the first absorption tower, by aldehydes in the first absorption tower Gas absorbs, and unabsorbed gases, which enters back into second absorption tower, to be continued to be absorbed, the tail gas come out by second absorption tower Entered exhaust combustion in burning boiler by pipeline, the vapor that the room of being filled with water in boiler generates enters second by return duct It is continued in pipeline, other gases are discharged by exhaust pipe and the 4th filter in the combustion chamber, will be in second absorption tower Absorbing liquid is pumped by the second material liquid being sent into the first absorption tower, and the liquid in the first absorption tower is collected, and acquisition contains hemiacetal Liquid, in producing preparation process, heat is adequately recycled, while the gases such as hydrogen generated are burned heel row It puts, is conducive to environment, while the aldehyde material that two absorption towers absorb production is set, improve absorption efficiency and assimilation effect, It is suitble to be widely popularized.
In the present invention unless specifically defined or limited otherwise, term " installation ", " connected ", " connection ", " fixation " etc. Term shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected;It can be machine Tool connects, and can also be electrical connection;It can be directly connected, can also can be indirectly connected through an intermediary two members Connection inside part.For the ordinary skill in the art, above-mentioned term can be understood in this hair as the case may be Concrete meaning in bright.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with Understanding without departing from the principles and spirit of the present invention can carry out these embodiments a variety of variations, modification, replace And modification, the scope of the present invention is defined by the appended.

Claims (5)

1. a kind of method producing hemiacetal using alcohol dehydrogenase, which is characterized in that be as follows:
S1:Raw polyol is pumped by the first material(8)And first filter(7)It is sent to mixing chamber after filtering is clean(3);
S2:Water tank(2)Interior water filling, passes through heater(4)Heated, the steam of generation passes through second pipe(6)Into Mixing chamber(3);
S3:Pressure fan(10)Start, air is passed through into blast pipe(9)By the second filter(11)It is sent into mixing after filtering is clean Room(3);
S4:The material that S1, S2 and S3 are sent into is by mixing indoor evaporator(12)Mixed gas is flashed to, mixed gas enters First gas-guide tube(15), pass through spark arrester(13)With third filter(14)Oxidation reactor is entered after filtering(16)It is interior, Oxidation reactor(16)It is interior to be oxidized to gaseous aldehyde by the catalytic action of catalyst;
S5:Gaseous aldehyde passes through the second gas-guide tube(17)Into cooling water tank(18)It is interior;
S6:Gas after cooling enters in cooler bin in S5, and cooling soft water is added in cooler bin in advance, is cooled down again;
S7:Mixed gas after cooling passes through third gas-guide tube(20)Into the first absorption tower(21)It is interior, on the first absorption tower (21)Interior to absorb gaseous aldehyde, unabsorbed gases enters back into second absorption tower(23)Interior continuation is absorbed;
S8:Pass through second absorption tower(23)Tail gas out enters burning boiler by pipeline(25)It is interior by exhaust combustion, boiler The vapor that the interior room of being filled with water generates enters second pipe by return duct(6)It inside continues with, other gases are in the combustion chamber Pass through exhaust pipe(28)With the 4th filter(29)Discharge;
S9:By second absorption tower(23)Interior absorbing liquid is pumped by the second material(24)Liquid is sent into the first absorption tower(21), receive Collect the first absorption tower(21)Interior liquid obtains the liquid containing hemiacetal;
S10:By the liquid meter obtained in S9 and packs and store;
The cooling water tank(18)The second interior gas-guide tube(17)It is S-type;The alcohol is dihydric alcohol;In step s 2, described to add The heating temperature of hot device is T, and unit is degree Celsius;The steam of generation is P in the pressure of mixing chamber, and unit is megapascal;It is described to add Hot temperature T and steam meet following relationship in the pressure of mixing chamber for P:P=αT;Wherein α is product coefficient, α 1.5-2.5.
2. device used by a kind of method according to claim 1 using alcohol dehydrogenase production hemiacetal, the device packet Include material box(1), water tank(2)And mixing chamber(3), the material box(1)Pass through first pipe(5)It is communicated in mixing chamber(3), institute State first pipe(5)The first material is equipped with to pump(8)And first filter(7), the water tank(2)Interior installation having heaters(4), institute State water tank(2)Pass through second pipe(6)It is communicated in mixing chamber(3), the mixing chamber(3)Upper side is also communicated with blast pipe(9), The blast pipe(9)On pressure fan is installed(10)With the second filter(11), the mixing chamber(3)Evaporator is inside installed (12), the mixing chamber(3)Side is connected with the first gas-guide tube(15), first gas-guide tube(15)It is anti-that side is communicated with oxidation Answer device(16), first gas-guide tube(15)On spark arrester is installed(13)With third filter(14), the oxidation reactor (16)Side is connected with the second gas-guide tube(17), second gas-guide tube(17)Side, which is run through, cooling water tank(18), described cold But water tank(18)Side is equipped with cooler bin(19), second gas-guide tube(17)It is communicated in cooler bin(19), the cooler bin (19)Side passes through third gas-guide tube(20)It is communicated with the first absorption tower(21), first absorption tower(21)Pass through the 4th air guide Pipe(22)It is communicated with second absorption tower(23), the second absorption tower(23)Bottom is communicated in the first absorption tower by pipeline (21), and the second material pump is installed on pipeline(24), the second absorption tower(23)Side is communicated with burning boiler by pipeline (25), the burning boiler(25)Top is connected with return duct(26), the return duct(26)It is communicated in second pipe(6);Institute State the second gas-guide tube(17)And cooling water tank(18)It is equipped with sealing ring through position;The material box(1), water tank(2), cooling water Case(18)And cooler bin(19)Top offer import, and import is equipped with sealing cover.
3. a kind of device producing hemiacetal using alcohol dehydrogenase according to claim 2, it is characterised in that:The burning pot Stove(25)Including combustion chamber and the room that is filled with water.
4. a kind of device producing hemiacetal using alcohol dehydrogenase according to claim 3, it is characterised in that:The combustion chamber Side is connected with exhaust pipe(28), the exhaust pipe(28)It is equipped with the 4th filter(29).
5. a kind of device producing hemiacetal using alcohol dehydrogenase according to claim 4, it is characterised in that:The return duct (26)And second pipe(6)Pass through three-way connection(27)Connection.
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DE2159975A1 (en) * 1971-12-03 1973-06-07 Veba Chemie Ag GLYOXAL SEMI-BACETALS, THE PROCESS FOR THEIR MANUFACTURING AND THEIR USE
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