CN107774209A - A kind of Ultrasound Instrument and pipeline reactor combined apparatus - Google Patents
A kind of Ultrasound Instrument and pipeline reactor combined apparatus Download PDFInfo
- Publication number
- CN107774209A CN107774209A CN201711263477.9A CN201711263477A CN107774209A CN 107774209 A CN107774209 A CN 107774209A CN 201711263477 A CN201711263477 A CN 201711263477A CN 107774209 A CN107774209 A CN 107774209A
- Authority
- CN
- China
- Prior art keywords
- pipeline
- reactor
- quenched
- material pot
- neutralization reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002604 ultrasonography Methods 0.000 title claims abstract description 17
- 239000000463 material Substances 0.000 claims abstract description 24
- 238000006386 neutralization reaction Methods 0.000 claims abstract description 18
- 238000006243 chemical reaction Methods 0.000 claims abstract description 10
- 241000628997 Flos Species 0.000 claims abstract description 4
- 239000006096 absorbing agent Substances 0.000 claims description 4
- -1 aldehyde compound Chemical class 0.000 abstract description 6
- 230000003321 amplification Effects 0.000 abstract description 6
- 238000003199 nucleic acid amplification method Methods 0.000 abstract description 6
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract description 5
- 235000011114 ammonium hydroxide Nutrition 0.000 abstract description 5
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract description 5
- 229910052740 iodine Inorganic materials 0.000 abstract description 5
- 239000011630 iodine Substances 0.000 abstract description 5
- 230000003647 oxidation Effects 0.000 abstract description 4
- 238000007254 oxidation reaction Methods 0.000 abstract description 4
- 230000008030 elimination Effects 0.000 abstract description 3
- 238000003379 elimination reaction Methods 0.000 abstract description 3
- 230000015572 biosynthetic process Effects 0.000 abstract description 2
- 238000004880 explosion Methods 0.000 abstract description 2
- 150000002825 nitriles Chemical class 0.000 abstract description 2
- 238000003786 synthesis reaction Methods 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 description 5
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- YHGWMROFZIEUCZ-UHFFFAOYSA-N N.I.I.I Chemical compound N.I.I.I YHGWMROFZIEUCZ-UHFFFAOYSA-N 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
- B01J19/10—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing sonic or ultrasonic vibrations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D53/00—Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols
- B01D53/14—Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases, aerosols by absorption
- B01D53/18—Absorbing units; Liquid distributors therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/18—Stationary reactors having moving elements inside
- B01J19/1812—Tubular reactors
- B01J19/1818—Tubular reactors in series
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The present invention relates to Ultrasound Instrument and pipeline reactor combined apparatus, mainly solve aldehyde compound and aoxidize elimination with iodine and ammoniacal liquor to prepare the technical problem easily exploded when the amplifications of nitrile compounds produces, be also applied for other reactions that can not amplify using ultrasound.Technical scheme is：A kind of Ultrasound Instrument and pipeline reactor combined apparatus, including pipeline reactor, material pot a and material pot b output pipes are connected by threeway blender with pipeline reactor, it is characterized in that pipeline reactor connects ultrasonic controller by ultrasonic generator, ultrasonic controller connects alarm, reactor is quenched by pipeline connection in pipeline reactor, reactor is quenched neutralization reaction kettle is connected by pipeline, neutralization reaction kettle connects product collecting tank by floss hole, reactor is quenched by pipeline connection in material pot c, and material pot d connects neutralization reaction kettle by pipeline.It is applied in the reaction of Oxidation of aldehydes synthesis nitrile, eliminates risk of explosion, is produced especially suitable for amplification.
Description
Technical field
The present invention relates to Ultrasound Instrument and pipeline reactor combined apparatus, and it applies the reaction in Oxidation of aldehydes synthesis nitrile
In, risk of explosion is eliminated, is produced especially suitable for amplification.
Background technology
Ultrasound Instrument is widely used in the research and development of laboratory scale at present, obvious with the reactor of factory, enlarge-effect, it is difficult to
Production is amplified in factory.Aldehydes is used as raw material for preparing nitrile compounds, and oxidation elimination is carried out using iodine and ammoniacal liquor
Reaction, reaction yield is higher, and operation is also easy, but because the accessory substance triiodide nitrogen of generation easily explodes, when amplification produces
Potential safety hazard is very big.
The content of the invention
It is an object of the invention to provide a kind of Ultrasound Instrument and pipeline reactor combined apparatus, mainly solves aldehyde compound and uses
Iodine and ammoniacal liquor carry out oxidation elimination and prepare the technical problem easily exploded during the amplification production of nitrile compounds, are also applied for other
The reaction that can not be amplified using ultrasound.
The technical scheme is that：A kind of Ultrasound Instrument and pipeline reactor combined apparatus, including pipeline reactor, material
Tank a and material pot b output pipes are connected by threeway blender with pipeline reactor, it is characterized in that pipeline reactor passes through ultrasound
Generator connects ultrasonic controller, ultrasonic controller connection alarm, and pipeline reactor is quenched reactor by pipeline connection, quenched
The reactor that goes out connects neutralization reaction kettle by pipeline, and neutralization reaction kettle connects product collecting tank by floss hole, and material pot c passes through
Reactor is quenched in pipeline connection, and material pot d connects neutralization reaction kettle by pipeline.
It is quenched after reactor connects pressure gauge by pipeline and is passed through alkaline gas absorber.Reactor and neutralization reaction is quenched
Kettle connecting line is provided with sample tap.
The beneficial effects of the invention are as follows：Once the power of ultrasonic generator deviates the power of setting, it will automatic alarm.Pipe
Road reactor can realize that the product of generation is quenched in time, reduce the generation of accessory substance.Extract the liquid that goes out continuously to be neutralized with acetic acid
Reaction solution is adjusted into neutrality, the stability of product can be improved.Aldehydes can be prepared nitrile compounds using iodine and ammoniacal liquor
Technique amplification production, eliminates security risk, is also suitable reaction using ultrasound with other, strong to process repeatability.The device
Automated condtrol can be realized, reduces personnel cost, improves production security.
Brief description of the drawings
Fig. 1 is present system connection diagram.
In figure：1- ultrasonic controllers, 2- alarms, 3- ultrasonic generators, 4- pipeline reactors, 5- threeway blenders, 6-
Reactor, 8- sample taps, 9- neutralization reaction kettles, 10- product collecting tanks, 11- alkaline gas absorbers, 12- is quenched in pressure gauge, 7-
Material pot a, 13- material pot b, 14- material pot c, 15- material pot d.
Embodiment
Reference picture 1, a kind of Ultrasound Instrument and pipeline reactor combined apparatus, including pipeline reactor 4, material pot a12 and thing
Batch can b13 output pipes are connected by threeway blender 5 with pipeline reactor 4, and pipeline reactor 4 is connected by ultrasonic generator 3
Ultrasonic controller 1 is connect, ultrasonic controller 1 connects alarm 2, and pipeline reactor 4 is quenched reactor 7 by pipeline connection, is quenched
Reactor 7 is passed through alkaline gas absorber 11 after connecting pressure gauge 6 by pipeline.Reactor 7 is quenched neutralization is connected by pipeline
Reactor 9, is quenched reactor 7 and the connecting line of neutralization reaction kettle 9 is provided with sample tap 8.Neutralization reaction kettle 9 is connected by floss hole
Practice midwifery product collecting tank 10, reactor 7 is quenched by pipeline connection in material pot c14, and material pot d15 connects neutralization reaction by pipeline
Kettle 9.During production, the solution of aldehydes and iodine is consecutively transferred to threeway blender 5 by pump P1 with certain flow rate in material pot a12
In, the ammoniacal liquor of mass percentage concentration 25% is consecutively transferred in threeway blender 5 by pump P2 with certain flow rate in material pot b13.
After two strands of materials mix in threeway blender in flow ipe reactor 4, ultrasonic generator 3（Shanghai life analysis ultrasonic instrument has
Limit company, FB-3600）It is placed among pipeline reactor, passes through ultrasonic controller 1（Shanghai Sheng Xi ultrasonic instruments Co., Ltd,
FB-3600）To control the power of ultrasonic generator in real time, if exception occurs in ultrasonic generator, will be feedbacked to alarm 2 and carry out
Alarm, reaction solution is continuously flowed into from pipeline reactor 4 to being quenched in reactor 7, while material pot c14 sulfite sodium solutions
Also it is consecutively transferred to be quenched in reactor 7 by pump P3 and excessive I is quenched in time2With accessory substance NI3, it is anti-after being quenched
Liquid is answered to be consecutively transferred to by pump P4 in neutralization reaction kettle 9, while acetum is also continuously shifted by pump P5 in material pot d15
Neutralized in time into neutralization reaction kettle 9, now product is in stable state, and product solution then is transferred into product collects
In tank.
Claims (3)
1. a kind of Ultrasound Instrument and pipeline reactor combined apparatus, including pipeline reactor, material pot a and material pot b output pipes
It is connected by threeway blender with pipeline reactor, it is characterized in that：Pipeline reactor connects ultrasound control by ultrasonic generator
Device, ultrasonic controller connection alarm, pipeline reactor are quenched reactor by pipeline connection, reactor are quenched and is connected by pipeline
Neutralization reaction kettle is connect, neutralization reaction kettle connects product collecting tank by floss hole, and reaction is quenched by pipeline connection in material pot c
Kettle, material pot d connect neutralization reaction kettle by pipeline.
2. a kind of Ultrasound Instrument according to claim 1 and pipeline reactor combined apparatus, it is characterized in that：Reactor is quenched to lead to
Alkaline gas absorber is passed through after crossing pipeline connection pressure gauge.
3. a kind of Ultrasound Instrument according to claim 1 and pipeline reactor combined apparatus, it is characterized in that：Be quenched reactor and
Neutralization reaction kettle connecting line is provided with sample tap.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711263477.9A CN107774209A (en) | 2017-12-05 | 2017-12-05 | A kind of Ultrasound Instrument and pipeline reactor combined apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711263477.9A CN107774209A (en) | 2017-12-05 | 2017-12-05 | A kind of Ultrasound Instrument and pipeline reactor combined apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107774209A true CN107774209A (en) | 2018-03-09 |
Family
ID=61430243
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711263477.9A Pending CN107774209A (en) | 2017-12-05 | 2017-12-05 | A kind of Ultrasound Instrument and pipeline reactor combined apparatus |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107774209A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111589394A (en) * | 2020-06-30 | 2020-08-28 | 江苏京控装备有限公司 | Ultrasonic homogeneous single-tube reactor |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130078704A1 (en) * | 2010-05-24 | 2013-03-28 | Xyleco, Inc. | Processing Chemicals |
| CN105348045A (en) * | 2015-11-25 | 2016-02-24 | 黑龙江鑫创生物科技开发有限公司 | Method for synthesizing pentafluorophenol by using continuous flow reaction |
| CN206355990U (en) * | 2016-11-11 | 2017-07-28 | 泰兴联创绝缘材料有限公司 | A kind of tubular reactor |
| CN207641450U (en) * | 2017-12-05 | 2018-07-24 | 上海合全药物研发有限公司 | A kind of Ultrasound Instrument and pipeline reactor combined apparatus |
-
2017
- 2017-12-05 CN CN201711263477.9A patent/CN107774209A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130078704A1 (en) * | 2010-05-24 | 2013-03-28 | Xyleco, Inc. | Processing Chemicals |
| CN105348045A (en) * | 2015-11-25 | 2016-02-24 | 黑龙江鑫创生物科技开发有限公司 | Method for synthesizing pentafluorophenol by using continuous flow reaction |
| CN206355990U (en) * | 2016-11-11 | 2017-07-28 | 泰兴联创绝缘材料有限公司 | A kind of tubular reactor |
| CN207641450U (en) * | 2017-12-05 | 2018-07-24 | 上海合全药物研发有限公司 | A kind of Ultrasound Instrument and pipeline reactor combined apparatus |
Non-Patent Citations (2)
| Title |
|---|
| 刘大华 等: "《合成橡胶工业手册》", 31 December 1991, 化学工业出版社 * |
| 赵临襄 等: "《化学制药工艺学》", 31 August 2015, 中国医药科技出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111589394A (en) * | 2020-06-30 | 2020-08-28 | 江苏京控装备有限公司 | Ultrasonic homogeneous single-tube reactor |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103087010B (en) | Synthesizing method of epoxy fatty acid ester | |
| CN207641450U (en) | A kind of Ultrasound Instrument and pipeline reactor combined apparatus | |
| CN206701242U (en) | A kind of pipeline reactor for fine chemistry industry production | |
| CN102773042A (en) | High temperature and high pressure reaction kettle provided with online sampling device | |
| CN107774209A (en) | A kind of Ultrasound Instrument and pipeline reactor combined apparatus | |
| CN203494509U (en) | Ultrasonic microwave production system of high-efficiency water treatment agent | |
| CN204745728U (en) | Vertical circulation leaching device of ultrasonic wave | |
| CN108855055A (en) | A kind of preparation method of the high activity hydroxide palladium carbon based on microreactor | |
| CN209481518U (en) | A kind of efficient etoxazole crude product preparation system | |
| US9115215B2 (en) | Method for completely dissolving and rapidly hydrolyzing cellulose, and uses of said method | |
| CN103497104B (en) | Method for producing citrate by using microchannel reactor | |
| CN102976897A (en) | Method for purifying tetrafluoro propanol | |
| CN102336781B (en) | Method and device for continuously preparing malathion | |
| CN110841585A (en) | Benzyl cyanide production device and use method thereof | |
| CN102764621A (en) | Sequentially working multifrequency contact ultrasound-assisted extraction and ultrasound-assisted reaction equipment | |
| CN211471264U (en) | Benzyl cyanide apparatus for producing | |
| CN113105380A (en) | Novel process for preparing peroxyacetic acid by using acetic acid as raw material through microreactor | |
| CN102838569B (en) | Method for synthesizing peach aldehyde by using microreactor device | |
| CN215312295U (en) | Catalyst on-line evaluation device for directly synthesizing hydrogen peroxide by using hydrogen and oxygen | |
| CN108192059B (en) | Microchannel continuous urea-formaldehyde resin production method and device | |
| CN201195061Y (en) | Low-temperature supersonic catalysis synthesis abstraction instrument | |
| CN112321530A (en) | Preparation method of continuous synthetic rubber vulcanization accelerator CBS | |
| CN220951451U (en) | Tubular quick quenching device for azide wastewater | |
| CN221182727U (en) | Preparation device of bicyclo [3.1.0] -3-hexanone | |
| CN215693953U (en) | Polyglycerol decoloration refining plant |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180309 |