CN107753782B - Traditional Chinese medicine compound tamponade agent for epistaxis and preparation method thereof - Google Patents
Traditional Chinese medicine compound tamponade agent for epistaxis and preparation method thereof Download PDFInfo
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- CN107753782B CN107753782B CN201711068720.1A CN201711068720A CN107753782B CN 107753782 B CN107753782 B CN 107753782B CN 201711068720 A CN201711068720 A CN 201711068720A CN 107753782 B CN107753782 B CN 107753782B
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- 239000003814 drug Substances 0.000 title claims abstract description 36
- 150000001875 compounds Chemical class 0.000 title claims abstract description 24
- 208000001780 epistaxis Diseases 0.000 title claims abstract description 20
- 239000003795 chemical substances by application Substances 0.000 title claims abstract description 19
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 210000003928 nasal cavity Anatomy 0.000 claims abstract description 28
- 229920000742 Cotton Polymers 0.000 claims abstract description 19
- 239000000843 powder Substances 0.000 claims abstract description 15
- 241001598107 Imperata Species 0.000 claims abstract description 14
- 238000000227 grinding Methods 0.000 claims abstract description 14
- 240000000249 Morus alba Species 0.000 claims abstract description 9
- 235000008708 Morus alba Nutrition 0.000 claims abstract description 9
- 229940056582 human hair preparation Drugs 0.000 claims abstract description 8
- 238000011049 filling Methods 0.000 claims abstract description 7
- 238000002156 mixing Methods 0.000 claims abstract description 7
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 244000025254 Cannabis sativa Species 0.000 claims abstract description 5
- 240000004980 Rheum officinale Species 0.000 claims abstract description 4
- 235000008081 Rheum officinale Nutrition 0.000 claims abstract description 4
- 238000002791 soaking Methods 0.000 claims abstract description 4
- 238000007598 dipping method Methods 0.000 claims description 3
- 208000032843 Hemorrhage Diseases 0.000 abstract description 19
- 230000000740 bleeding effect Effects 0.000 abstract description 18
- 230000000694 effects Effects 0.000 abstract description 13
- 238000011160 research Methods 0.000 abstract description 4
- 239000000829 suppository Substances 0.000 abstract description 4
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000023597 hemostasis Effects 0.000 description 10
- 238000000034 method Methods 0.000 description 10
- 241000219061 Rheum Species 0.000 description 8
- 235000009411 Rheum rhabarbarum Nutrition 0.000 description 8
- 239000008280 blood Substances 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 8
- 241000283973 Oryctolagus cuniculus Species 0.000 description 5
- 210000002850 nasal mucosa Anatomy 0.000 description 5
- KWGRBVOPPLSCSI-WPRPVWTQSA-N (-)-ephedrine Chemical compound CN[C@@H](C)[C@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WPRPVWTQSA-N 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 206010061218 Inflammation Diseases 0.000 description 3
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 3
- 239000000945 filler Substances 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 229910052709 silver Inorganic materials 0.000 description 3
- 239000004332 silver Substances 0.000 description 3
- 240000001624 Espostoa lanata Species 0.000 description 2
- 235000009161 Espostoa lanata Nutrition 0.000 description 2
- 206010028748 Nasal obstruction Diseases 0.000 description 2
- 206010039101 Rhinorrhoea Diseases 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 239000003610 charcoal Substances 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000007906 compression Methods 0.000 description 2
- KWGRBVOPPLSCSI-UHFFFAOYSA-N d-ephedrine Natural products CNC(C)C(O)C1=CC=CC=C1 KWGRBVOPPLSCSI-UHFFFAOYSA-N 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 229960002179 ephedrine Drugs 0.000 description 2
- 230000002439 hemostatic effect Effects 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 210000001370 mediastinum Anatomy 0.000 description 2
- 210000004877 mucosa Anatomy 0.000 description 2
- 208000011309 nasal bleeding Diseases 0.000 description 2
- 208000010753 nasal discharge Diseases 0.000 description 2
- GKCBAIGFKIBETG-UHFFFAOYSA-N tetracaine Chemical compound CCCCNC1=CC=C(C(=O)OCCN(C)C)C=C1 GKCBAIGFKIBETG-UHFFFAOYSA-N 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 230000008733 trauma Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241001552669 Adonis annua Species 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 208000032456 Hemorrhagic Shock Diseases 0.000 description 1
- 206010024453 Ligament sprain Diseases 0.000 description 1
- 206010024769 Local reaction Diseases 0.000 description 1
- 206010028740 Nasal dryness Diseases 0.000 description 1
- 208000030880 Nose disease Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010038776 Retching Diseases 0.000 description 1
- 206010039509 Scab Diseases 0.000 description 1
- 206010049771 Shock haemorrhagic Diseases 0.000 description 1
- 208000010040 Sprains and Strains Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 208000034158 bleeding Diseases 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 231100000410 bloody scab Toxicity 0.000 description 1
- 238000007596 consolidation process Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000008029 eradication Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 238000000554 physical therapy Methods 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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- 230000009885 systemic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 229940126673 western medicines Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
Abstract
The invention belongs to the field of natural medicine research, and particularly relates to a traditional Chinese medicine compound tamponade agent for epistaxis and a preparation method thereof. The plugging agent is prepared from the following raw materials in parts by weight: 1-5 parts of cogongrass rhizome, 0.5-2 parts of rheum officinale and 1-3 parts of white mulberry root-bark. The preparation method comprises the following steps: grinding lalang grass rhizome, radix et rhizoma Rhei and cortex Mori into powder, mixing, dissolving the above medicinal powder with small grinding oil, making into oil, and soaking cotton sliver in the oil. When the nasal cavity filling device is used, the cotton sliver soaked with the oil is taken out, and the surface of the cotton sliver is dipped with the crinis carbonisatus and then is filled spirally along the inner side of the nasal cavity wall. The traditional Chinese medicine compound suppository can directly act on an affected part, has the effects of clearing heat and removing toxicity, can quickly stop bleeding and has more comprehensive treatment.
Description
Technical Field
The invention belongs to the field of natural medicine research, and particularly relates to a traditional Chinese medicine compound tamponade agent for epistaxis and a preparation method thereof.
Background
Epistaxis is one of the most common and troublesome diseases of the ear-nose-throat department. It can be caused by nasal diseases or systemic diseases. Epistaxis is mostly unilateral, and bilateral epistaxis can occur in a few cases; the bleeding is not consistent, the mild one is only bloody nasal discharge, the severe one can cause hemorrhagic shock, and the repeated nasal bleeding can cause anemia. At present, although there are many methods for clinical hemostasis treatment, there are many problems in the actual clinical work, which brings great pain to patients.
Currently, for treating long-term epistaxis, there are local hemostasis, cauterization, anterior nasal cavity tamponade, etc. However, the methods bring great pain to patients, and some methods have unobvious effects and poor treatment effects. In particular, in the anterior nasal cavity tamponade method, the blood crust newly formed adheres to the tamponade yarn, and the tamponade yarn is pulled away at the same time when being taken out, so that re-bleeding occurs. In the improved technology, the air bag or water bag compression hemostasis method is that hemostatic air bags with various shapes are made of rubber films and are placed at the bleeding part of the nasal cavity, and the hemostatic air bags are inflated or filled with water to perform compression hemostasis. But the physical hemostasis is adopted, and the material for hemostasis is a rubber material, so that the long-term use is inconvenient, the local tissue can be subjected to extravasated blood and necrosis due to excessive sealing, and the short-term hemostasis can be realized only. When the nasal cavity is filled, medicines such as blood coagulation and antibiosis are usually added, western medicines are usually used, but the side effect is large, and the eradication effect is not good.
The cause of epistaxis is mainly caused by inflammation inside the nasal cavity, trauma and sprain caused by external force, temperature and humidity of the atmosphere and other factors. In principle, traditional Chinese medicine mostly takes traditional decoction as a main part, and can perform treatment according to specific symptoms and symptoms in a dialectical mode, but the treatment period is long and the curative effect is slow; western medicine mostly adopts physical therapy to treat emergency, and has remarkable curative effect, but less medicines for recovery and consolidation after treatment. Therefore, the development of novel Chinese medicinal preparations by using modern pharmaceutical technology has become a modern research hotspot.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine compound tamponade agent for epistaxis and a preparation method thereof, aiming at overcoming the defects of the prior art, so that the pain of patients is reduced.
In order to realize the purpose, the invention adopts the following technical scheme:
a traditional Chinese medicine compound tamponade agent for epistaxis is prepared from the following raw materials in parts by weight: 1-5 parts of cogongrass rhizome, 0.5-2 parts of rheum officinale and 1-3 parts of white mulberry root-bark.
The preparation method of the traditional Chinese medicine compound tamponade agent comprises the following steps: grinding lalang grass rhizome, radix et rhizoma Rhei and cortex Mori into powder, mixing, dissolving the above medicinal powder with small grinding oil, making into oil, and soaking cotton sliver in the oil.
The application method of the prepared traditional Chinese medicine compound tamponade agent comprises taking out the cotton sliver soaked with the oil agent, dipping crinis Carbonisatus on the surface of the cotton sliver, and spirally filling the cotton sliver along the inner side of nasal cavity wall.
The cogongrass rhizome is cold in nature, and the medicine has the efficacy of stopping bleeding and cooling blood, and is recorded in Ben Cao gang mu: "stopping vomiting of female blood, vomiturition, lung heat and dyspnea; in addition, the rhubarb has the effects of relaxing bowels, purging heat and inducing fire to descend, the powder prepared by the rhubarb is dissolved by a proper solvent, and the rhubarb is taken to act together with the lalang grass rhizome according to the drug effect so as to ensure that the drug effect can be better played; on the basis, a proper amount of the white mulberry root-bark is added, the white mulberry root-bark not only can reduce swelling and resist inflammation, but also has an antibacterial effect, can replace chemical medicines to play a role of antibiotics when the anterior nasal cavity is filled, and has low side effect and good effect because the white mulberry root-bark is a natural medicine; when in use, a small amount of crinis Carbonisatus is added on the cotton strip for hemostasis, which is called as follows: the hair is carbonized human blood, so the hair is called as crinis, the carbonized human blood has the functions of hemostasis and antibiosis, has good hemostasis effect and is particularly suitable for patients with large nasal cavity bleeding amount.
Compared with the prior art, the invention has the beneficial effects that: the traditional Chinese medicine compound tamponade agent can directly act on an affected part, clears heat and toxic materials, can quickly stop bleeding, has more comprehensive treatment, has no toxic or side effect because all components of the tamponade agent are natural medicines, has excellent treatment effect on epistaxis, and can not be adhered to newly formed bloody scab again to bleed after a cotton sliver is dipped in the prepared oil solution and put into a nasal cavity. The components of the invention are selected from local common medicinal materials, the price is low, and the economic burden of patients is reduced.
Detailed Description
The present invention is further illustrated by the following specific examples.
Example 1
A Chinese medicinal compound suppository for treating epistaxis is prepared from the following raw materials: 5g of cogongrass rhizome, 2g of rhubarb and 3g of white mulberry root-bark.
The preparation of the traditional Chinese medicine compound filling agent comprises the following steps: grinding rhizoma Imperatae 5g, radix et rhizoma Rhei 2g, and cortex Mori 3g into powder, mixing, dissolving the powder with 5ml small oil, and making into oil, and soaking cotton sliver in the oil.
During the use, will soak the silver of finish and take out, the silver surface dips in and gets the crinis Carbonisatus charcoal, orders the patient seat, rinses the nasal cavity with normal saline earlier, adds several drops of 1% dicaine with 1% ephedrine cotton balls again, conveniently sees the bleeding point clearly, adopts spiral filling method, will dip in the silver that has the crinis Carbonisatus charcoal and fill along patient's nasal cavity wall inboard.
Taking a cotton sliver with enough length to conveniently form a spiral filling mode, grinding 5g of cogongrass rhizome, 2g of rhubarb and 3g of cortex mori into powder, mixing, dissolving the powder with 5ml of small grinding oil to prepare an oil solution, and immersing the cotton sliver in the oil solution. Taking out the cotton sliver soaked with the oil solution, and dipping the surface of the cotton sliver with crinis Carbonisatus. Order the patient to sit, firstly use normal saline to clean the nasal cavity, then add a few drops of 1% dicaine on a 1% ephedrine cotton ball, conveniently see the bleeding point clearly, adopt spiral filling method, fill the cotton sliver dipped with the crinis carbonisatus along the inner side of the nasal cavity wall.
Example 2
A Chinese medicinal compound suppository for treating epistaxis is prepared from the following raw materials: 1g of cogongrass rhizome, 1g of rhubarb and 1g of white mulberry root-bark.
The preparation of the traditional Chinese medicine compound filling agent comprises the following steps: grinding 1g of lalang grass rhizome, 1g of rhubarb and 1g of cortex mori into powder, mixing, dissolving the powder with 2ml of small grinding oil to prepare an oil solution, and immersing the cotton sliver in the oil solution.
The procedure was as in example 1.
Example 3
A Chinese medicinal compound suppository for treating epistaxis is prepared from the following raw materials: 3g of cogongrass rhizome, 0.5g of rhubarb and 2g of white mulberry root-bark.
The preparation of the traditional Chinese medicine compound filling agent comprises the following steps: grinding 3g of cogongrass rhizome, 0.5g of rheum officinale and 2g of cortex mori radicis into powder, mixing, dissolving the powder with 2ml of small grinding oil to prepare an oil solution, and immersing the cotton sliver in the oil solution.
The procedure was as in example 1.
Example 4
The invention relates to a traditional Chinese medicine compound tamponade agent for epistaxis, which is used for the irritation research:
taking 6 rabbits, and uniformly filling the cotton slivers soaked with the small grinding oil in the right nasal cavities of the rabbits to serve as a contrast; the traditional Chinese medicine compound plugging agent is uniformly plugged into the nasal cavity on the left side. Three times daily for seven consecutive days. The rabbits are completely killed 24 hours after the last administration, the two sides of the nostrils are cut, the nasal mucosa parts are turned outwards, the local reaction condition of the mucosa in the nasal cavity is observed and the nasal mucosa is scored, and the nasal mucosa irritation of the traditional Chinese medicine compound tamponade is judged. And compared to a control. The results show that: the mucus on the nasal mucosa of the rabbits treated by the traditional Chinese medicine compound tamponade agent is clear and transparent, has no turbidity, and the blood vessels on the surface of the mucosa have no congestion and edema, so that the traditional Chinese medicine compound tamponade agent has no irritant reaction to the nasal mucosa of the rabbits, and is safe.
Example 5
In a certain grandson, a woman is 67 years old, a nasal cavity mediastinum repair operation is performed before one month due to nasal cavity mediastinum deflection, intermittent nasal bleeding does not occur due to obvious inducement after operation, a first-visit hospital adopts nasal cavity gauze packing, infusion is performed to diminish inflammation, bleeding stops, and the nasal cavity bleeds heavily again after two days. The traditional Chinese medicine compound plugging agent is used once a day for 15 minutes once, and 10 days are a treatment course. After the medicine is used for half a day, bleeding stops, the bleeding frequency and the bleeding amount are obviously reduced after the medicine is used for one day, the bleeding is once or twice a day, a plurality of drops of the medicine are applied every time, the bleeding stops after one treatment course, the medicine is stopped after two treatment courses of insisting on, and the medicine does not relapse after follow-up visit after half a year.
Li in certain age, male, 5 years old, three years old. Three years ago, the single nasal cavity bleeds after trauma, and blood drops down or a large amount of blood is not stopped, so the nasal cavity becomes bright red, and the symptoms of nasal dryness, nasal obstruction, watery nasal discharge and the like are accompanied. The patent of the invention is used for wiping the nasal cavity blood to find bleeding points, the plugging agent of the invention is uniformly plugged into the bleeding nasal cavity once a day, 15 minutes each time, 10 days as a treatment course, after 1 treatment course, the symptoms of nasal obstruction, nasal cavity dryness and the like of a patient are obviously relieved, no bleeding occurs, the medicine is stopped after 1 treatment course is insisted on, and no bleeding occurs again after half a year of follow-up visit.
Claims (2)
1. A traditional Chinese medicine compound tamponade agent for epistaxis is characterized by being prepared from the following raw materials in parts by weight: 1-5 parts of cogongrass rhizome, 0.5-2 parts of rheum officinale and 1-3 parts of white mulberry root-bark;
the preparation method comprises the following steps: grinding lalang grass rhizome, radix et rhizoma Rhei and cortex Mori into powder, mixing, dissolving the above medicinal powder with small grinding oil, making into oil, and soaking cotton sliver in the oil.
2. The compound Chinese medicinal tamponade for epistaxis according to claim 1, wherein the tamponade is prepared by taking out the tampon soaked with the oil, dipping crinis carbonisatus on the surface of the tampon, and spirally filling the tampon along the inner side of nasal cavity wall.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711068720.1A CN107753782B (en) | 2017-11-03 | 2017-11-03 | Traditional Chinese medicine compound tamponade agent for epistaxis and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711068720.1A CN107753782B (en) | 2017-11-03 | 2017-11-03 | Traditional Chinese medicine compound tamponade agent for epistaxis and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107753782A CN107753782A (en) | 2018-03-06 |
| CN107753782B true CN107753782B (en) | 2021-03-19 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711068720.1A Active CN107753782B (en) | 2017-11-03 | 2017-11-03 | Traditional Chinese medicine compound tamponade agent for epistaxis and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107753782B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5546964A (en) * | 1994-02-02 | 1996-08-20 | Stangerup; Sven-Eric | Method for treating a bleeding nose |
| CN103860924A (en) * | 2014-02-16 | 2014-06-18 | 王树军 | Traditional Chinese medicine for treating epistaxis |
-
2017
- 2017-11-03 CN CN201711068720.1A patent/CN107753782B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5546964A (en) * | 1994-02-02 | 1996-08-20 | Stangerup; Sven-Eric | Method for treating a bleeding nose |
| CN103860924A (en) * | 2014-02-16 | 2014-06-18 | 王树军 | Traditional Chinese medicine for treating epistaxis |
Non-Patent Citations (6)
| Title |
|---|
| "桑白皮茅根粥适用于肺热鼻衄以及鼻炎";无;《https://www.pingguolv.com/shipu/10929.html》;20140914;第1页 * |
| 无."桑白皮茅根粥适用于肺热鼻衄以及鼻炎".《https://www.pingguolv.com/shipu/10929.html》.2014,第1页. * |
| 赵媛等.鼻腔填塞在鼻出血治疗中的应用.《中国眼耳鼻喉科杂志》.2016,(第02期), * |
| 陈改娥等.黄芩白茅根汤治疗火热鼻衄200例临床疗效分析.《现代中医药》.2002,(第04期), * |
| 黄芩白茅根汤治疗火热鼻衄200例临床疗效分析;陈改娥等;《现代中医药》;20021231(第04期);第11-12页 * |
| 鼻腔填塞在鼻出血治疗中的应用;赵媛等;《中国眼耳鼻喉科杂志》;20160325(第02期);第138-140页 * |
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| CN107753782A (en) | 2018-03-06 |
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Application publication date: 20180306 Assignee: Dalian Xinzerui Technology Co.,Ltd. Assignor: DALIAN University Contract record no.: X2023210000261 Denomination of invention: A traditional Chinese medicine compound filling agent for nosebleeds and its preparation method Granted publication date: 20210319 License type: Common License Record date: 20231130 |
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| OL01 | Intention to license declared | ||
| OL01 | Intention to license declared |