CN107753104A - Compatible water-cooled microwave ablation needle of a kind of magnetic and preparation method thereof - Google Patents
Compatible water-cooled microwave ablation needle of a kind of magnetic and preparation method thereof Download PDFInfo
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- CN107753104A CN107753104A CN201711249494.7A CN201711249494A CN107753104A CN 107753104 A CN107753104 A CN 107753104A CN 201711249494 A CN201711249494 A CN 201711249494A CN 107753104 A CN107753104 A CN 107753104A
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- RVTZCBVAJQQJTK-UHFFFAOYSA-N oxygen(2-);zirconium(4+) Chemical compound [O-2].[O-2].[Zr+4] RVTZCBVAJQQJTK-UHFFFAOYSA-N 0.000 claims description 44
- 229910001928 zirconium oxide Inorganic materials 0.000 claims description 44
- 239000004020 conductor Substances 0.000 claims description 41
- 239000000463 material Substances 0.000 claims description 12
- 238000003466 welding Methods 0.000 claims description 11
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- 230000005540 biological transmission Effects 0.000 claims description 3
- 238000004364 calculation method Methods 0.000 claims description 3
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- 238000000576 coating method Methods 0.000 claims description 3
- 206010028980 Neoplasm Diseases 0.000 abstract description 21
- 238000013461 design Methods 0.000 abstract description 4
- 238000002595 magnetic resonance imaging Methods 0.000 abstract description 4
- 239000002918 waste heat Substances 0.000 abstract description 4
- 238000010438 heat treatment Methods 0.000 abstract description 3
- 230000005855 radiation Effects 0.000 abstract description 3
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 20
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- QCWXUUIWCKQGHC-UHFFFAOYSA-N Zirconium Chemical compound [Zr] QCWXUUIWCKQGHC-UHFFFAOYSA-N 0.000 description 2
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- 238000002604 ultrasonography Methods 0.000 description 2
- 229910052726 zirconium Inorganic materials 0.000 description 2
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00059—Material properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00589—Coagulation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00964—Features of probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
- A61B2018/1869—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves with an instrument interstitially inserted into the body, e.g. needles
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Electromagnetism (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Otolaryngology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
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Abstract
The invention provides a kind of microwave melt needle, part used in microwave melt needle provided by the invention selects non-magnetic material, the microwave tumour ablation art that can be used safely under Magnetic resonance imaging guiding, it is to human body without ionising radiation, image resolution ratio is high, arbitrary orientation is imaged, and can effectively improve the success rate of operation.Microwave melt needle uses the design that coaxial cable multi-notch is combined with nonmagnetic becket, eliminates the shank tail waste heat problem in existing microwave melt needle heating process, ablation gained region is approximately one spherical, meets most tumors shape；It is equally possible that according to the shape of different tumours, the interval between notch quantity and the width and notch of notch is adjusted, different ablation shapes is obtained, ablation efficiency can be effectively improved in the case where not damaging normal structure.
Description
Technical field
The invention belongs to technical field of medical instruments, and in particular to a kind of compatible water-cooled microwave ablation needle of magnetic and its preparation
Method.
Background technology
At present, the microwave tumour ablation art of minimally invasive intervention is widely used in clinic.Microwave tumour ablation art is that microwave disappears
Melt pin and be transferred to microwave melt needle front end in image-guided lower insertion tissue focus, the microwave energy as caused by microwave ablation instrument
Lasting transmitting, makes Junctional tissue heat production, and a spherical thermal field is formed in several minutes, and central temperature is higher than 100 DEG C, edge temperature
Degree is more than 60 DEG C so that tissue coagulation, dehydration necrosis.Microwave tumour ablation art efficiency high, wound are small, depth of interaction to tissue
It is controllable with scope.
Most of microwave tumour ablation art be CT or ultrasound guidance by microwave melt needle percutaneous puncture into tumour
Heart district domain, but the image guiding of the minimally invasive intervention as main flow, CT and ultrasound have some limitations.Ultrasonoscopy resolution ratio
Not high, it is in terms of tumor boundaries are judged by a definite limitation；CT radiates big to doctor and patient.Comparatively speaking, nuclear magnetic resonance
Imaging technique does not injure to human body, and it has, and higher accuracy, image resolution ratio are high, soft tissue contrast is high, any more
Orientation imaging, imaging parameters enrich.
However, existing available microwave melt needle can not be made by being limited in terms of material technology under magnetic resonance environment
With limiting the development of microwave tumour ablation art.What is more important, existing available microwave melt needle ablation gained region is all
For a strip spheroid-like, and most of tumours are all close to spheroidal, in order to completely inactivate tumor tissues, it is necessary to add
The scope melted greatly, so inherently damages human normal tissue, and unnecessary injury is caused to human body.
The content of the invention
In view of this, the technical problem to be solved in the present invention be to provide a kind of compatible water-cooled microwave ablation needle of magnetic and its
Preparation method, the compatible water-cooled microwave ablation needle of magnetic provided by the invention can be used safely in the microwave under Magnetic resonance imaging guiding
Tumour ablation art, ablation areas is adjustable, and ablation efficiency can be effectively improved in the case where not damaging normal structure, and needle tubing is integrated
Construction, it is safe.
The invention provides a kind of compatible water-cooled microwave ablation needle of magnetic, including：
Zirconium oxide needle tubing (1), the zirconium oxide needle tubing include needle point and hollow needle body；
Coaxial cable (2), the coaxial cable (2) include inner wire, dielectric and outer conductor, the coaxial cable
(2) inner wire of front end is connected with outer conductor and is arranged on inside the hollow needle body, and the surface of the coaxial cable is certainly
The front end of the coaxial cable along its axis direction offer 8~10 it is being communicated with the dielectric, equidistantly distributed
Annular notches；
It is arranged inside the hollow needle body, and is sheathed on the nonmagnetic metal on the outer conductor surface of coaxial cable (2)
Ring (3), the nonmagnetic becket (3) be disposed furthest from the side of the notch of coaxial cable (2) front end and be close to it is described most
Notch away from coaxial cable (2) front end；In the hollow needle body, the nonmagnetic becket (3) to needle point end
The space at end is confined space；
It is opened in the water inlet and delivery port of hollow needle body end；
The radio frequency (RF) coaxial connector (6) being connected with the tail end of the coaxial cable (2).
Preferably, the width of each notch is identical, and the width of the notch is 0.1~0.5mm, the adjacent notch
At intervals of 0.5~1mm, the depth of the notch is the thickness of the outer conductor.
Preferably, coaxial cable (2) front end and described between the notch of the coaxial cable (2) front end
Interval is more than the distance between adjacent notch.
Preferably, the coaxial cable is magnetic compatibility coaxial cable, and the inner wire and outer conductor of the coaxial cable are nothing
Magnetic metal.
Preferably, the internal diameter of the nonmagnetic becket (3) is more than the coaxial cable (2) external diameter, the nonmagnetic gold
The external diameter for belonging to ring (3) is less than the internal diameter of the hollow needle body, and the width of the nonmagnetic becket (3) is an EWL
± 5mm, the calculation formula of the EWL are as follows：
Wherein, c is the velocity of wave in vacuum, and f is used microwave frequency, ∈rIt is normal for the relative dielectric of ripple transmission medium
Number.
Preferably, the water inlet is connected with water inlet pipe (4), and the delivery port is connected with outlet pipe (5), the water inlet pipe
(4) it is non-magnetic material, the outlet pipe (5) is non-magnetic material, and the radio frequency (RF) coaxial connector (6) is nonmagnetic conduction material
Material.
Preferably, the external diameter of the coaxial cable is 0.8mm-2.2mm, and the length of the coaxial cable is 135mm-
215mm。
Preferably, the needle point and the integrated construction of hollow needle body, the needle point is solid cone, described
The height of cone is 3mm-6mm, and the length of the hollow needle body is 109mm-192mm, and the external diameter of the hollow needle body is
1.6mm-3.0mm, the internal diameter of the hollow needle body is 1.0mm-2.6mm.
Preferably, in addition to it is arranged at the needle handle (7) of the zirconium oxide needle tubing tail end.
Present invention also offers a kind of preparation method of the compatible water-cooled microwave ablation needle of above-mentioned magnetic, comprise the following steps：
A) inner wire of coaxial cable (2) front end is connected with outer conductor welding；
B) on the surface of coaxial cable (2), from the position of the coaxial cable (2) front end along its axis direction cutting 8~
10 annular notches communicated with the dielectric, equidistantly distributed；
C nonmagnetic becket (3)) is inserted in the coaxial cable surface, and it is with adhesive that nonmagnetic becket (3) is solid
Due to the notch farthest away from coaxial cable (2) front end side and be close to the notch farthest away from coaxial cable (2) front end；
D) in nonmagnetic becket (3) the surface coating a layer of adhesive, and by the first half of the coaxial cable (2)
Divide in the hollow needle body of the insertion zirconium oxide needle tubing (1) after being contacted to the front end of the coaxial cable (2) with the end of needle point,
Bonding is dried, it is confined space to make the nonmagnetic becket (3) to the space of the tip end；
E) water inlet pipe (4) water inlet is connected, outlet pipe (5) is connected with delivery port；
F) by the tail end adhesive seal of the zirconium oxide needle tubing (1)；
G) radio frequency (RF) coaxial connector (6) is connected with the tail end welding of the coaxial cable (2), and needle handle (7) is installed
In the zirconium oxide needle tubing tail end.
Compared with prior art, the compatible water-cooled microwave ablation needle of a kind of magnetic, it is characterised in that including：Zirconium oxide needle tubing
(1), the zirconium oxide needle tubing includes needle point and hollow needle body；Coaxial cable (2), the coaxial cable (2) include interior lead
Body, dielectric and outer conductor, the inner wire of the front end of the coaxial cable (2) are connected with outer conductor and are arranged on described hollow
Needle body inside, the surface of the coaxial cable along its axis direction offer 8~10 it is being communicated with the dielectric, etc.
The annular notches of spacing distribution；It is arranged inside the hollow needle body, and be sheathed on the outer conductor surface of coaxial cable (2)
Nonmagnetic becket (3), the nonmagnetic becket (3) are disposed furthest from the side of the notch of coaxial cable (2) front end simultaneously
It is close to the notch farthest away from coaxial cable (2) front end；In the hollow needle body, the nonmagnetic becket (3) is extremely
The space of the tip end is confined space；It is opened in the water inlet and delivery port of hollow needle body end；With the coaxial electrical
The connected radio frequency (RF) coaxial connector (6) of the tail end of cable (2).Part used in microwave melt needle provided by the invention is selected without magnetic material
Material, the microwave tumour ablation art that can be used safely under Magnetic resonance imaging guiding, it is to human body without ionising radiation, image resolution ratio
Height, arbitrary orientation are imaged, and can effectively improve the success rate of operation.Microwave melt needle using coaxial cable multi-notch with it is nonmagnetic
The design that becket is combined, eliminate the shank tail waste heat problem in existing microwave melt needle heating process, ablation gained area
Domain is approximately one spherical, meets most tumors shape；It is equally possible that according to the shape of different tumours, notch number is adjusted
Interval between amount and the width and notch of notch, obtains different ablation shapes, in the case where not damaging normal structure
Ablation efficiency can be effectively improved.In addition, the zirconium oxide needle tubing of microwave melt needle provided by the invention using integration, improve with
Past microwave melt needle need to weld in addition or the phenomenon of bonded needle, avoids syringe needle easy to fall off in surgical procedure, human body is caused
Unnecessary injury；In addition, zirconia material is easy to puncture to human body non-hazardous and firm.
Brief description of the drawings
Fig. 1 is the structural representation of the compatible water-cooled microwave ablation needle of magnetic provided by the invention.
Embodiment
The invention provides a kind of compatible water-cooled microwave ablation needle of magnetic, including：
Zirconium oxide needle tubing (1), the zirconium oxide needle tubing include needle point and hollow needle body；
Coaxial cable (2), the coaxial cable (2) include inner wire, dielectric and outer conductor, the coaxial cable
(2) inner wire of front end is connected with outer conductor and is arranged on inside the hollow needle body, and the surface of the coaxial cable is certainly
The front end of the coaxial cable along its axis direction offer 8~10 it is being communicated with the dielectric, equidistantly distributed
Annular notches；
It is arranged inside the hollow needle body, and is sheathed on the nonmagnetic metal on the outer conductor surface of coaxial cable (2)
Ring (3), the nonmagnetic becket (3) be disposed furthest from the side of the notch of coaxial cable (2) front end and be close to it is described most
Notch away from coaxial cable (2) front end；In the hollow needle body, the nonmagnetic becket (3) to needle point end
The space at end is confined space；
It is opened in the water inlet and delivery port of hollow needle body end；
The radio frequency (RF) coaxial connector (6) being connected with the tail end of the coaxial cable (2).
Referring to Fig. 1, Fig. 1 is the structural representation of the compatible water-cooled microwave ablation needle of magnetic provided by the invention.In Fig. 1,1 is
Zirconium oxide needle tubing, 2 be coaxial cable, and 2-1 is notch, and 3 be nonmagnetic becket, and 4 be water inlet pipe, and 5 be outlet pipe, and 6 be radio frequency
Coaxial connector, 7 be needle handle.
The compatible water-cooled microwave ablation needle of magnetic provided by the invention includes zirconium oxide needle tubing (1), the zirconium oxide needle tubing bag
Include needle point and hollow needle body.
In the present invention, the needle point is the integrated design with hollow needle body, so as to avoid syringe needle in surgical procedure
It is easy to fall off, unnecessary injury is caused to human body.Wherein, needle point is preferably solid cone, is easy to puncture in surgical procedure；Institute
The length for stating hollow needle body is 109mm-192mm, preferably 120~160mm；The external diameter of the hollow needle body is 1.6mm-
3.0mm, preferably 2.0~2.5mm；The internal diameter of the hollow needle body is 1.0mm-2.6mm, preferably 1.5~2.0mm.It is hard
Zirconium oxide needle tubing (1) be easy to puncture in surgical procedure, and hollow needle body can provide passage for water circulation.
The compatible water-cooled microwave ablation needle of magnetic provided by the invention also includes coaxial cable (2), coaxial cable (2) bag
Inner wire, dielectric and outer conductor are included, the inner wire of the front end of the coaxial cable (2) is connected and is arranged on outer conductor
Inside the hollow needle body, the surface of the coaxial cable offers 8 from the front end of the coaxial cable along its axis direction
~10 annular notches communicated with the dielectric, equidistantly distributed；
In the present invention, the coaxial cable is magnetic compatibility, and the inner wire is nonmagnetic metal, preferably silver-plated copper
Line, the outer conductor are nonmagnetic metal, preferably plate the seamless annealing copper tube of ternary alloy three-partalloy.
The first half of the coaxial cable (2) is arranged inside the hollow needle body, after the coaxial cable (2)
Half part is extended to outside needle body.
The external diameter of the coaxial cable is 0.8mm-2.2mm, preferably 1.2~1.8mm；The length of the coaxial cable is
135mm-215mm, preferably 150~180mm.
The inner wire of coaxial cable (2) front end is connected with outer conductor, and is touched with the joining distal ends of the needle point.
The surface of the coaxial cable from the front end of the coaxial cable along its axis direction offer 8~10 with it is described
Annular notches that dielectric communicates, equidistantly distributed.
Coaxial cable (2) front end and the interval between the notch of the coaxial cable (2) front end are big
In the distance between adjacent notch.
In the present invention, the number of the notch is 8~10, and the width of each notch is identical, and the width of the notch is
0.1~0.5mm, the adjacent notch at intervals of 0.5~1mm, the depth of the notch is the thickness of the outer conductor.
Wherein, the control of the width of institute's otch and notch so that microwave energy is maximumlly outwards radiate, in group
Knit middle formation thermal field, ablated tumor；Interval between adjacent notch so that energy maximization concentrates on notch periphery；This hair
The bright control by notch number, width of rebate and adjacent notch interval, ablation areas of different shapes can be obtained.
The compatible water-cooled microwave ablation needle of magnetic provided by the invention also includes being arranged in the hollow needle body and being arranged
Nonmagnetic becket (3) in the outer conductor surface of coaxial cable (2), the nonmagnetic becket (3) are disposed furthest from together
Simultaneously it is close to the notch farthest away from coaxial cable (2) front end in the side of the notch of shaft cable (2) front end.Wherein, it is described farthest
Side from the notch of coaxial cable (2) front end is close to the side of the end of coaxial cable.
The internal diameter of the nonmagnetic becket (3) is more than the coaxial cable (2) external diameter, the nonmagnetic becket (3)
External diameter be less than the hollow needle body internal diameter, the width of the nonmagnetic becket (3) is an EWL ± 5mm,
The calculation formula of the EWL is as follows：
Wherein, λ is EWL, and c is the velocity of wave in vacuum, and f is used microwave frequency, ∈rFor ripple transmission medium
Relative dielectric constant.
In the present invention, the nonmagnetic becket (3) is selected from without magnetic conductance electric metal, preferably copper, silver or aluminium, more preferably
For copper.
Added nonmagnetic becket (3) can eliminate needle tubing tail waste heat problem in ablation procedure so that ablation areas connects
Nearly elliposoidal or spheroidal, meet tumor shape.
The compatible water-cooled microwave ablation needle of magnetic provided by the invention also include being opened in the water inlet of hollow needle body end with
Delivery port.
In certain specific embodiments of the invention, the water inlet is connected with water inlet pipe (4), and the delivery port is with going out
Water pipe (5) is connected, and the water inlet pipe (4) is non-magnetic material, and the outlet pipe (5) is non-magnetic material, the RF coaxial
Connector (6) is nonmagnetic conductive material.
In certain specific embodiments of the invention, the water inlet pipe (4) and outlet pipe (5) intercalation are to described hollow
It is oppositely arranged inside needle body and with the coaxial cable (2) for axle center, the part of the water inlet pipe (4) and outlet pipe (5) is in institute
State in hollow needle body, remainder extends to the external side of the hollow needle.
The water inlet of the water inlet pipe (4) is connected with the first plastic flexible pipe, the convenient pin to the water-cooled microwave ablation needle
Water is passed through in pipe, the delivery port of the outlet pipe (5) is connected with the second plastic flexible pipe, will be delivered to pin for the water for cooling down needle body
In vitro, water circulation effectively reduces the temperature of needle wall in ablation procedure, avoids calcination skin.
The water inlet pipe (4) is non-magnetic material, preferably titanium alloy tube, earthenware or copper pipe；The outlet pipe (5) is
Non-magnetic material, preferably titanium alloy tube, earthenware or copper pipe.
In the hollow needle body, end to the space of the nonmagnetic becket (3) of the hollow needle body is
Confined space.
The compatible water-cooled microwave ablation needle of magnetic provided by the invention also includes what is be connected with the tail end of the coaxial cable (2)
Radio frequency (RF) coaxial connector (6).
The radio frequency (RF) coaxial connector (6) is nonmagnetic conductive material, and the radio frequency (RF) coaxial connector (6) is silver-plated by aluminum
Material manufacture.
The compatible water-cooled microwave ablation needle of magnetic provided by the invention also includes the pin for being arranged at the zirconium oxide needle tubing tail end
Handle (7).
Present invention also offers a kind of preparation method of the compatible water-cooled microwave ablation needle of above-mentioned magnetic, comprise the following steps：
A) inner wire of coaxial cable (2) front end is connected with outer conductor welding；Specifically, by coaxial cable (2) front end
Outer conductor peeled off with intermediate insulating layer, the welding of inner wire and outer conductor is connected.
B) on the surface of coaxial cable (2), from the position of the coaxial cable (2) front end along its axis direction cutting 8~
10 annular notches communicated with the dielectric, equidistantly distributed；
In the present invention, the method for the cutting is preferably line cutting technology.
C nonmagnetic becket (3)) is inserted in the coaxial cable surface, and it is with adhesive that nonmagnetic becket (3) is solid
Due to the notch farthest away from coaxial cable (2) front end side and be close to the notch farthest away from coaxial cable (2) front end.Institute
It is preferably high temperature resistant waterproof silicone adhesive to state binding agent.
D) on nonmagnetic becket (3) surface and lower surface coating a layer of adhesive, and by the coaxial cable (2)
First half insert in the hollow needle body of the zirconium oxide needle tubing (1) to the front end of the coaxial cable (2) and the end of needle point
After end in contact, bonding is dried, it is confined space to make the nonmagnetic becket (3) to the space of the tip end, i.e.,
Inside hollow needle body, the space sealing between the nonmagnetic becket (3) to the needle point, all notches are all in this
In confined space, the latter half of the coaxial cable (2) extends to the external side of the hollow needle；Described adhesive is preferably resistance to
High temperature waterproof silicone adhesive.
E) water inlet pipe (4) water inlet is connected, outlet pipe (5) is connected with delivery port, by water inlet pipe (4) and outlet pipe
(5) water inlet respectively with the hollow needle body end of the zirconium oxide needle tubing (1) is connected with delivery port, and with the coaxial cable
(2) it is oppositely arranged for axle center, the part of the water inlet pipe (4) and outlet pipe (5) is in the hollow needle body, remainder extension
To the external side of the hollow needle；
The water inlet of the water inlet pipe (4) is connected with the first plastic flexible pipe, the convenient pin to the water-cooled microwave ablation needle
Water is passed through in pipe, the delivery port of the outlet pipe (5) is connected with the second plastic flexible pipe, will be delivered to pin for the water for cooling down needle body
In vitro, water circulation effectively reduces the temperature of needle wall in ablation procedure, avoids calcination skin.By the water inlet pipe and outlet pipe with
Plastic flexible pipe is connected, described connected using UV glue bonding.
F) by the tail end adhesive seal of the zirconium oxide needle tubing (1), it is preferred to use UV glue is sealed；
G) radio frequency (RF) coaxial connector (6) is connected with the tail end welding of the coaxial cable (2), and needle handle (7) is installed
In the zirconium oxide needle tubing tail end.
Part used in microwave melt needle provided by the invention selects non-magnetic material, can be used safely in Magnetic resonance imaging and draw
Microwave tumour ablation art under leading, to human body without ionising radiation, image resolution ratio is high, arbitrary orientation imaging, can effectively carry for it
The success rate of height operation.Microwave melt needle uses the design that coaxial cable multi-notch is combined with nonmagnetic becket, eliminates existing
There is the shank tail waste heat problem in microwave melt needle heating process, ablation gained region is approximately one spherical, meets majority
Tumor shape；It is equally possible that according to the shape of different tumours, adjust between notch quantity and the width and notch of notch
Interval, obtain different ablation shapes, ablation efficiency can be effectively improved in the case where not damaging normal structure.In addition, this
Using the zirconium oxide needle tubing of integration, improving conventional microwave melt needle need to weld or glue in addition the microwave melt needle that invention provides
The phenomenon of syringe needle is connect, avoids syringe needle easy to fall off in surgical procedure, unnecessary injury is caused to human body；In addition, zirconium oxide material
Material is easy to puncture to human body non-hazardous and firm.
For a further understanding of the present invention, with reference to the embodiment water cooling microwave ablation compatible to magnetic provided by the invention
Pin and preparation method thereof is illustrated, and protection scope of the present invention is not limited by the following examples.
Embodiment 1
A kind of compatible water-cooled microwave ablation needle of magnetic is present embodiments provided, including：Zirconium oxide needle tubing 1, coaxial cable 2,
Copper ring 3, water inlet pipe 4, outlet pipe 5, radio frequency (RF) coaxial connector 6 and needle handle 7.
Specifically include：
Zirconium oxide needle tubing (1), the zirconium oxide needle tubing include needle point and hollow needle body；
Coaxial cable (2), the coaxial cable (2) include inner wire, dielectric and outer conductor, the coaxial cable
(2) inner wire of front end is connected with outer conductor and is arranged on inside the hollow needle body, and the surface of the coaxial cable is certainly
The front end of the coaxial cable along its axis direction offer 8~10 it is being communicated with the dielectric, equidistantly distributed
Annular notches；
It is arranged inside the hollow needle body, and is sheathed on the nonmagnetic metal on the outer conductor surface of coaxial cable (2)
Ring (3), the nonmagnetic becket (3) be disposed furthest from the side of the notch of coaxial cable (2) front end and be close to it is described most
Notch away from coaxial cable (2) front end；In the hollow needle body, the nonmagnetic becket (3) to needle point end
The space at end is confined space；
It is opened in the water inlet and delivery port of hollow needle body end；
The radio frequency (RF) coaxial connector (6) being connected with the tail end of the coaxial cable (2).
It is arranged at the needle handle (7) of the zirconium oxide needle tubing tail end.
The front end inner wire of the coaxial cable 2 connects with outer conductor welding, and the outer conductor of coaxial cable 2 uses wire cutting skill
Art cuts 10 notch 2-1, and copper ring 3 is inserted in the outside of last notch on the surface of coaxial cable 2 (i.e. close to coaxial cable end
The side at end), the both ends of copper ring 3 are be bonded with coaxial cable 2 using high temperature resistant waterproof silicone adhesive, then resistance in one layer of copper ring surface smear
High temperature waterproof silicone adhesive, then coaxial cable 2 is inserted in zirconium oxide needle tubing 1 to front end and bonding is dried, water inlet pipe 4 is with going out
Water pipe 5 is aoxidizing with being connected respectively with water inlet and delivery port, and at the tail end of copper ring 3 place being inserted into zirconium oxide needle tubing 1
The tail end of zirconium needle tubing 1 smearing UV glue is simultaneously fast by zirconium oxide needle tubing 1 and coaxial cable 2, water inlet pipe 4, outlet pipe 5 with ultra violet lamp
Speed is adhesively fixed and water shutoff, radio frequency (RF) coaxial connector 6 are welded on the tail end of coaxial cable 2.
The external diameter of zirconium oxide needle tubing 1 is 2.2mm, and total length 170mm, front end is solid cone, is highly 4mm,
Rear end is hollow needle tube, and internal diameter is 1.9mm, length 166mm more than the external diameter of copper ring 3.
The coaxial cable 2 is non-magnetic, external diameter 1.19mm, length 196mm, the front end inner wire of coaxial cable 2
Connected with outer conductor welding, cut 10 notches successively since front end, the width of each notch is 0.2mm, notch and notch
The distance between be 1mm, first notch is from being 4.5mm with a distance from the front end of coaxial cable 2.
The external diameter of copper ring 3 is 1.5mm, internal diameter 1.25mm, length 18mm, is inserted in the last of the surface of coaxial cable 2
Behind one notch, and it is adhesively fixed using high temperature resistant waterproof silicone adhesive.
The water inlet pipe 4, outlet pipe 5 are manufactured by titanium alloy material, external diameter 0.5mm, internal diameter 0.3mm, water inlet pipe 4
Length is 150mm, and the length of outlet pipe 5 is 100mm, and water inlet pipe 4, outlet pipe 5 are glued in tail end using UV glue and plastic flexible pipe
Connect, so as to be changed with the water pipe of the outside of needle handle 7.
The radio frequency (RF) coaxial connector 6 is the silver-plated joint of aluminum, the tail end of coaxial cable 2 is welded in, with microwave generator
It is connected.
The needle handle 7 is manufactured by plastic material, water inlet pipe 4, outlet pipe 5, the radio frequency that will extend into outside hollow needle body
Coaxial connector 6 envelopes.
The water-cooled microwave ablation needle can use under magnetic resonance, use finite element analysis software, emulation ablation gained area
Domain is approximately the shape that a radius is 34mm spheroidals.
Embodiment 2
A kind of compatible water-cooled microwave ablation needle of magnetic is present embodiments provided, including：Zirconium oxide needle tubing 1, coaxial cable 2,
Copper ring 3, water inlet pipe 4, outlet pipe 5, radio frequency (RF) coaxial connector 6 and needle handle 7.
Specifically include：
Zirconium oxide needle tubing (1), the zirconium oxide needle tubing include needle point and hollow needle body；
Coaxial cable (2), the coaxial cable (2) include inner wire, dielectric and outer conductor, the coaxial cable
(2) inner wire of front end is connected with outer conductor and is arranged on inside the hollow needle body, and the surface of the coaxial cable is certainly
The front end of the coaxial cable along its axis direction offer 8~10 it is being communicated with the dielectric, equidistantly distributed
Annular notches；
It is arranged inside the hollow needle body, and is sheathed on the nonmagnetic metal on the outer conductor surface of coaxial cable (2)
Ring (3), the nonmagnetic becket (3) be disposed furthest from the side of the notch of coaxial cable (2) front end and be close to it is described most
Notch away from coaxial cable (2) front end；In the hollow needle body, the nonmagnetic becket (3) to needle point end
The space at end is confined space；
It is opened in the water inlet and delivery port of hollow needle body end；
The radio frequency (RF) coaxial connector (6) being connected with the tail end of the coaxial cable (2).
It is arranged at the needle handle (7) of the zirconium oxide needle tubing tail end.
The front end inner wire of the coaxial cable 2 connects with outer conductor welding, and the outer conductor of coaxial cable 2 uses wire cutting skill
Art cuts 10 notch 2-1, and copper ring 3 is inserted in the outside of last notch on the surface of coaxial cable 2 (i.e. close to coaxial cable end
The side at end), the both ends of copper ring 3 are be bonded with coaxial cable 2 using high temperature resistant waterproof silicone adhesive, then resistance in one layer of copper ring surface smear
High temperature waterproof silicone adhesive, then coaxial cable 2 is inserted in zirconium oxide needle tubing 1 to front end and bonding is dried, water inlet pipe 4 is with going out
Water pipe 5 is aoxidizing with being connected respectively with water inlet and delivery port, and at the tail end of copper ring 3 place being inserted into zirconium oxide needle tubing 1
The tail of zirconium needle tubing 1
End smearing UV glue is simultaneously fast by zirconium oxide needle tubing 1 and coaxial cable 2, water inlet pipe 4, outlet pipe 5 with ultra violet lamp
Speed is adhesively fixed and water shutoff, radio frequency (RF) coaxial connector 6 are welded on the tail end of coaxial cable 2.
The external diameter of zirconium oxide needle tubing 1 is 2.2mm, and total length 170mm, front end is filled arrows shape, and length is
4mm, rear end are hollow needle tube, and internal diameter is 1.9mm, length 166mm more than the external diameter of copper ring 3.
The coaxial cable 2 is non-magnetic, a diameter of 1.19mm, length 196mm, the front end inner wire of coaxial cable 2
Connect with outer conductor welding, cuts 8 notches successively since front end, the width of each notch is 0.5mm, notch and notch it
Between distance be 0.5mm, first notch is from being 4.5mm with a distance from the front end of coaxial cable 2.
The external diameter of copper ring 3 is 1.5mm, internal diameter 1.25mm, length 10mm, is inserted in the last of the surface of coaxial cable 2
Behind one notch, and it is adhesively fixed using high temperature resistant waterproof silicone adhesive.
The water inlet pipe 4, outlet pipe 5 are manufactured by titanium alloy material, external diameter 0.5mm, internal diameter 0.3mm, water inlet pipe 4
Length is 148mm, and the length of outlet pipe 5 is 98mm, and water inlet pipe 4, outlet pipe 5 are glued in tail end using UV glue and plastic flexible pipe
Connect, so as to be changed with the water pipe of the outside of needle handle 7.
The radio frequency (RF) coaxial connector 6 is the silver-plated joint of aluminum, the tail end of coaxial cable 2 is welded in, with microwave generator
It is connected.
The needle handle 7 is manufactured by plastic material, and water inlet pipe 4, outlet pipe 5, radio frequency (RF) coaxial connector 6 are enveloped.
The water-cooled microwave ablation needle can use under magnetic resonance, use finite element analysis software, emulation ablation gained area
Domain is approximately a spheroid shape, short axle 34mm, major axis 42mm.
Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (10)
- A kind of 1. compatible water-cooled microwave ablation needle of magnetic, it is characterised in that including：Zirconium oxide needle tubing (1), the zirconium oxide needle tubing include needle point and hollow needle body；Coaxial cable (2), the coaxial cable (2) include inner wire, dielectric and outer conductor, the coaxial cable (2) The inner wire of front end is connected with outer conductor and is arranged on inside the hollow needle body, and the surface of the coaxial cable is from described same The front end of shaft cable offers 8~10 annular grooves communicated with the dielectric, equidistantly distributed along its axis direction Mouthful；It is arranged inside the hollow needle body, and is sheathed on the nonmagnetic becket on the outer conductor surface of coaxial cable (2) (3), the nonmagnetic becket (3) is disposed furthest from the side of the notch of coaxial cable (2) front end and is close to described farthest From the notch of coaxial cable (2) front end；In the hollow needle body, the nonmagnetic becket (3) to the tip end Space be confined space；It is opened in the water inlet and delivery port of hollow needle body end；The radio frequency (RF) coaxial connector (6) being connected with the tail end of the coaxial cable (2).
- 2. water-cooled microwave ablation needle according to claim 1, it is characterised in that the width of each notch is identical, described The width of notch is 0.1~0.5 mm, and the adjacent notch is to be led outside described at intervals of 0.5~1mm, the depth of the notch The thickness of body.
- 3. water-cooled microwave ablation needle according to claim 1, it is characterised in that coaxial cable (2) front end with it is described Interval between the notch of the coaxial cable (2) front end is more than the distance between adjacent notch.
- 4. water-cooled microwave ablation needle according to claim 1, it is characterised in that the coaxial cable is magnetic compatibility coaxial electrical Cable, the inner wire and outer conductor of the coaxial cable are nonmagnetic metal.
- 5. water-cooled microwave ablation needle according to claim 1, it is characterised in that the internal diameter of the nonmagnetic becket (3) More than the coaxial cable (2) external diameter, the external diameter of the nonmagnetic becket (3) is less than the internal diameter of the hollow needle body, institute The width for stating nonmagnetic becket (3) is an EWL ± 5mm, and the calculation formula of the EWL is as follows：<mrow> <mi>&lambda;</mi> <mo>=</mo> <mfrac> <mi>c</mi> <mrow> <mi>f</mi> <msqrt> <msub> <mo>&Element;</mo> <mi>r</mi> </msub> </msqrt> </mrow> </mfrac> </mrow>Wherein, c is the velocity of wave in vacuum, and f is used microwave frequency, ∈rFor the relative dielectric constant of ripple transmission medium.
- 6. water-cooled microwave ablation needle according to claim 1, it is characterised in that the water inlet is connected with water inlet pipe (4), The delivery port is connected with outlet pipe (5), and the water inlet pipe (4) is non-magnetic material, and the outlet pipe (5) is nonmagnetic material Material, the radio frequency (RF) coaxial connector (6) is nonmagnetic conductive material.
- 7. water-cooled microwave ablation needle according to claim 1, it is characterised in that the external diameter of the coaxial cable is 0.8mm- 2.2mm, the length of the coaxial cable is 135mm-215mm.
- 8. water-cooled microwave ablation needle according to claim 1, it is characterised in that the needle point is with the hollow needle body Integrated structure, the needle point are solid cone, and the height of the cone is 3mm-6mm, the length of the hollow needle body Spend for 109mm-192mm, the external diameter of the hollow needle body is 1.6mm-3.0mm, and the internal diameter of the hollow needle body is 1.0mm- 2.6mm。
- 9. water-cooled microwave ablation needle according to claim 1, it is characterised in that also include being arranged at the zirconium oxide needle tubing The needle handle (7) of tail end.
- 10. a kind of preparation method of the compatible water-cooled microwave ablation needle of magnetic as claimed in any one of claims 1 to 9 wherein, it is special Sign is, comprises the following steps：A) inner wire of coaxial cable (2) front end is connected with outer conductor welding；B) on the surface of coaxial cable (2), 8~10 are cut from the position of the coaxial cable (2) front end along its axis direction Annular notches communicated with the dielectric, equidistantly distributed；C nonmagnetic becket (3)) is inserted in the coaxial cable surface, and is fixed on nonmagnetic becket (3) with adhesive Farthest away from the side of the notch of coaxial cable (2) front end and it is close to the notch farthest away from coaxial cable (2) front end；D) in nonmagnetic becket (3) the surface coating a layer of adhesive, and the first half of the coaxial cable (2) is inserted Enter after being contacted in the hollow needle body of the zirconium oxide needle tubing (1) to the front end of the coaxial cable (2) with the end of needle point, carry out Bonding is dried, it is confined space to make the nonmagnetic becket (3) to the space of the tip end；E) water inlet pipe (4) water inlet is connected, outlet pipe (5) is connected with delivery port；F) by the tail end adhesive seal of the zirconium oxide needle tubing (1)；G) radio frequency (RF) coaxial connector (6) is connected with the tail end welding of the coaxial cable (2), and needle handle (7) is installed on institute State zirconium oxide needle tubing tail end.
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| CN201711249494.7A CN107753104A (en) | 2017-12-01 | 2017-12-01 | Compatible water-cooled microwave ablation needle of a kind of magnetic and preparation method thereof |
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| CN109330681A (en) * | 2018-12-06 | 2019-02-15 | 安徽大中润科技有限公司 | Magnetic compatible water-cooling microwave ablation needle and manufacturing method thereof |
| CN109330680A (en) * | 2018-12-04 | 2019-02-15 | 安徽大中润科技有限公司 | Magnetic compatible dipole microwave ablation needle |
| CN113827784A (en) * | 2021-09-27 | 2021-12-24 | 东劢医疗科技(苏州)有限公司 | Medical nano heat-non-conductive composite material and preparation method and application thereof |
| CN114469329A (en) * | 2018-05-25 | 2022-05-13 | 南通融锋医疗科技有限公司 | Microwave ablation antenna for GGO treatment |
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Application publication date: 20180306 |