CN107753012B - Magnetocardiogram signal quality evaluation method, system and server - Google Patents
Magnetocardiogram signal quality evaluation method, system and server Download PDFInfo
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Abstract
The invention provides a method, a system and a server for evaluating quality of magnetocardiogram signals, wherein the method for evaluating the quality of the magnetocardiogram signals comprises the following steps: preprocessing the collected MCG data for recording magnetocardiogram signals generated by the heart electrical activity; identifying the R peak of a QRS wave in the preprocessed MCG data, and carrying out period segmentation on the preprocessed MCG data; calculating a plurality of quality evaluation parameters associated with the MCG data to evaluate the quality of the magnetocardiogram signal based on the MCG data after the period division; judging the grades of the quality evaluation parameters according to a plurality of evaluation threshold values corresponding to the quality evaluation parameters; and evaluating the quality of the magnetocardiogram signal according to the grades of the plurality of quality evaluation parameters. The method overcomes the defect of low evaluation reliability of the existing signal quality evaluation method, improves the reliability of the quality evaluation of the magnetocardiogram signal, has high operation speed, and can be applied to the real-time analysis of the signal quality during MCG on-line acquisition.
Description
Technical Field
The invention belongs to the field of biomedical signal analysis, relates to an evaluation method and an evaluation system, and particularly relates to a quality evaluation method, a quality evaluation system and a quality evaluation server for magnetocardiogram signals.
Background
The Magnetocardiograph (MCG) can record the evolution process of the magnetic field generated by the electrical activity of the heart over time, contains important information for evaluating the heart function, and can be used for diagnosing heart diseases such as coronary heart disease, myocardial infarction, arrhythmia and the like. However, the magnetocardiogram signal is very weak and is easily interfered by the external environment, and the quality of the magnetocardiogram signal can be weakened by the opened subway, the elevator moving up and down, and the like.
The quality of the magnetocardiogram signals is directly related to the reliability of the late-stage heart disease diagnosis, so that the quality of the magnetocardiogram signals needs to be evaluated, and if the evaluation result of the magnetocardiogram data acquired at this time is poor, an operator of the magnetocardiogram system is recommended to acquire the magnetocardiogram data again.
In the prior art, the signal quality evaluation method only divides the heart sound signals into five grades by one parameter (quality factor), and the classification reliability is not high due to insufficient classification basis;
or the prior art also includes a method for evaluating signal quality by qualitatively analyzing each of a plurality of noise sources in a physiological signal to obtain a corresponding plurality of qualitative ratings, however, the frequency range of magnetocardiogram signals is 0-100Hz, and the frequency range of some low-frequency noise sources, such as muscle noise sources (from unintentional muscle contraction of a patient due to anxiety), motion artifact noise sources (from patient movement), etc., is also within 0-100Hz, so that it is difficult to effectively extract these noises from magnetocardiogram data, and the reliability of the signal quality evaluation result is lowered, and thus, the method is not suitable for evaluating magnetocardiogram signal quality.
Therefore, it is an urgent technical problem to be solved by the practitioners in the art to provide a method, a system, and a server for evaluating quality of magnetocardiogram signals, so as to solve the defect in the prior art that quality of magnetocardiogram signals cannot be accurately evaluated according to characteristics of magnetocardiogram signals, and reliability of quality judgment results of magnetocardiogram signals is low.
Disclosure of Invention
In view of the above drawbacks of the prior art, an object of the present invention is to provide a method, a system, and a server for evaluating quality of magnetocardiogram signals, which are used to solve the problem that the reliability of quality judgment result of magnetocardiogram signals is not high due to the fact that quality of magnetocardiogram signals cannot be accurately evaluated according to characteristics of magnetocardiogram signals in the prior art.
To achieve the above and other related objects, an aspect of the present invention provides a quality evaluation method for magnetocardiogram signals, including the steps of: preprocessing the collected MCG data for recording magnetocardiogram signals generated by the heart electrical activity; identifying the R peak of a QRS wave in the preprocessed MCG data, and carrying out period segmentation on the preprocessed MCG data; calculating a plurality of quality evaluation parameters associated with the MCG data to evaluate the quality of the magnetocardiogram signal based on the MCG data after the period division; judging the grades of the quality evaluation parameters according to a plurality of evaluation threshold values corresponding to the quality evaluation parameters; and evaluating the quality of the magnetocardiogram signal according to the grades of the plurality of quality evaluation parameters.
In an embodiment of the present invention, the method for evaluating quality of magnetocardiogram signals further includes: preprocessing acquired ECG data used to record electrical signals generated by electrical activity of the heart; identifying the R peak of a QRS wave in the preprocessed ECG data, and carrying out cycle segmentation on the preprocessed ECG data; based on the cycle segmented ECG data, a quality assessment parameter is calculated comprising a plurality of quality assessment parameters associated with the MCG data and the ECG data for assessing the quality of the magnetocardiogram signal.
In an embodiment of the present invention, the step of performing cycle segmentation on the preprocessed MCG data and ECG data includes: calculating an average period of the preprocessed MCG data and ECG data; wherein the identified average period of the pre-processed MCG data and ECG dataRtiIs the time corresponding to the ith R peak in the preprocessed MCG data/ECG data, Rti+1The time corresponding to the i +1 th R peak in the preprocessed MCG data/ECG data; n is a radical of1The number of the identified R waves in the preprocessed MCG data/ECG data; taking the time corresponding to the R peak in the identified preprocessed MCG data and ECG data as a reference point, taking 0.4 average cycles before the reference point, and taking 0.6 average cycles after the reference point, so as to respectively perform cycle segmentation on the preprocessed MCG data and the ECG data to form a computing cycle, and segmenting the preprocessed MCG data and the ECG data according to the computing cycle.
In an embodiment of the invention, the quality assessment parameter associated with the MCG data and the ECG data includes an average correlation coefficient of the preprocessed MCG data and the ECG data; calculating average correlation coefficient of the preprocessed MCG data and ECG dataComprises the following steps: calculating absolute correlation coefficient | r of preprocessed MCG data and ECG data in each calculation period i1,2,3 … N, i is the data of MCGCalculating the serial number of the periods;
xj,j=1,2,3,...,M,xjthe data of the MCG in one calculation period is obtained, j is the serial number of the MCG data, and M is the total number of the MCG data in one calculation period;for MCG data x in one calculation periodjAverage value of (d); y isj,j=1,2,3,...,M,yjIs ECG data in a calculation period, and j is an ECG data serial number;is y in one cyclejAverage value of (d); calculating the average correlation coefficient of the preprocessed MCG data and ECG data in all calculation periodsAnd N is the number of calculation cycles in the MCG data.
In an embodiment of the present invention, the quality assessment parameters associated with the MCG data and the ECG data further include a Ratio; the step of calculating the available proportion Ratio includes: judging the absolute correlation coefficient | r of the preprocessed MCG data and the ECG data in each calculation period according to a judgment criterioniIf is good or bad, the judgment criterion isWherein, sigma is a threshold value for judging the good and bad correlation coefficient, and ziIs the result of the discrimination; counting the number G of good absolute correlation coefficients of the preprocessed MCG data and the preprocessed ECG data in all calculation periods, and calculating the available proportionAnd N is the number of calculation cycles in the MCG data.
In an embodiment of the present inventionWherein the quality assessment parameters associated with the MCG data further comprise an R variance of the pre-processed MCG data; the step of calculating the R variance of the preprocessed MCG data comprises: counting the variance R of R peaks of N calculation periods in the preprocessed MCG datavar,RiFor the ith R peak in the pre-processed MCG data,is the average of all R peaks.
In an embodiment of the present invention, the quality evaluation parameters associated with the MCG data further include a mean variance and a maximum variance of the preprocessed MCG data; the step of calculating the mean and maximum variance of the preprocessed MCG data comprises: calculating the variance of QRS wave base values in a calculation period of the preprocessed MCG datai is 1,2,3 … N, which is the serial number of the calculated cycles in the MCG data; QRS wave base value B of preprocessed MCG data in one calculation periodjIs MCG data value within a preset base value time range, wherein the preset base value time range is T2-TMoment of start of cycle0.33T; wherein the content of the first and second substances,k is a base value BjThe number of the (c) is,is a base value BjAverage value of (d); variance of QRS wave base value in a calculation period according to preprocessed MCG dataCalculating the average base value variance of the preprocessed MCG data in all calculation periodsAnd maximum variance of the contributions: wherein the mean variance of the contributionsN is the number of calculation periods in MCG data; the maximum base value variance of the preprocessed MCG data is the QRS base value variance in all calculation periodsIs measured.
In an embodiment of the invention, the quality evaluation parameter associated with the MCG data further includes an average signal-to-noise ratio of the preprocessed MCG dataAnd SNRmin(ii) a Calculating average signal-to-noise ratio of preprocessed MCG dataAnd SNRminComprises the following steps: calculating the SNR of the preprocessed MCG data in each calculation periodiI is 1,2,3 … N, which is the serial number of the calculated cycles in the MCG data;Rifor the R peak value of the ith calculation cycle of the preprocessed MCG data,calculating the variance of the base value of the ith calculation period of the preprocessed MCG data; according to SNR of the preprocessed MCG data in each calculation periodiCalculating the average signal-to-noise ratio of the preprocessed MCG dataSNR of preprocessed MCG dataminFor all SNR calculation periodsiIs measured.
In an embodiment of the present invention, the grades of the quality evaluation parameters include a first grade, a second grade, and a third grade; the levels of magnetocardiogram signal quality include a first level, a second level, and a third level; the step of evaluating the quality of the magnetocardiogram signal according to the grade of the plurality of quality evaluation parameters comprises the following steps: judging whether the number of the quality evaluation parameters belonging to the first level is larger than a number threshold value of the level for representing the quality of the magnetocardiogram signal as the first level; if so, indicating that the quality grade of the magnetocardiogram signal is a first grade, and if not, continuously judging whether the number of the quality evaluation parameters belonging to a third grade is larger than a threshold value of the number for indicating that the grade of the quality of the magnetocardiogram signal is the third grade; if yes, the quality grade of the magnetocardiogram signal is represented as a third grade, and if not, the quality grade of the magnetocardiogram signal is represented as a second grade.
Another aspect of the present invention provides a quality evaluation system for magnetocardiogram signals, including: the preprocessing module is used for preprocessing the acquired MCG data used for recording the magnetocardiogram signals generated by the cardiac electrical activity; the segmentation module is used for identifying the R peak of the QRS wave in the preprocessed MCG data and periodically segmenting the preprocessed MCG data; the calculation module is used for calculating a plurality of quality evaluation parameters which are related to the MCG data and used for evaluating the quality of the magnetocardiogram signals based on the MCG data after the period division; the evaluation module is used for judging the grades of the quality evaluation parameters according to the evaluation threshold values of the quality evaluation parameters; and evaluating the quality of the magnetocardiogram signal according to the grades of the plurality of quality evaluation parameters.
The invention further provides a server which comprises the magnetocardiogram signal quality evaluation system.
As described above, the magnetocardiogram signal quality evaluation method, system and server of the present invention have the following advantages:
the quality evaluation method, the system and the server of the magnetocardiogram signal overcome the defect of low reliability of the quality evaluation of the magnetocardiogram signal by the existing signal quality evaluation method, and provide a reliable system and a method which are suitable for the quality evaluation of the magnetocardiogram signal. The invention comprehensively considers the magnetocardiogram signal characteristics, and proposes seven parameters from MCG and ECG data: the method has the advantages that the method comprises the steps of average correlation coefficient, the available proportion of MCG and ECG, R variance, average base value variance, maximum base value variance, average SNR, minimum SNR and the like of MCG, and utilizes a voting mode to give qualitative rating to the signal quality of MCG, so that the reliability of magnetocardiogram signal quality evaluation is improved, the operation speed is high, and the method can be applied to real-time analysis of the signal quality during MCG online acquisition.
Drawings
Fig. 1 is a flow chart illustrating a magnetocardiogram signal quality evaluation method according to an embodiment of the present invention.
Fig. 2 is a schematic flow chart of step S3 in the method for evaluating quality of magnetocardiogram signals according to the present invention.
Fig. 3 is a schematic flow chart of step S6 in the method for evaluating quality of magnetocardiogram signals according to the present invention.
FIG. 4 is a diagram showing the magnetocardiogram signals with different noise contents and the quality evaluation results according to the present invention.
Fig. 5 is a schematic structural diagram of a magnetocardiogram signal quality evaluation system according to an embodiment of the present invention.
Fig. 6 is a schematic structural diagram of a server according to an embodiment of the present invention.
Description of the element reference numerals
1 magnetocardiogram signal quality evaluation system
11 preprocessing module
12 identification module
13 division module
14 calculation module
15 evaluation module
131 first dividing unit
132 second dividing unit
141 first calculation unit
142 second computing unit
143 third calculation unit
144 fourth calculation unit
145 fifth calculation unit
146 sixth calculation unit
147 seventh calculation Unit
S1-S6
S31-S33
Detailed Description
The embodiments of the present invention are described below with reference to specific embodiments, and other advantages and effects of the present invention will be easily understood by those skilled in the art from the disclosure of the present specification. The invention is capable of other and different embodiments and of being practiced or of being carried out in various ways, and its several details are capable of modification in various respects, all without departing from the spirit and scope of the present invention. It is to be noted that the features in the following embodiments and examples may be combined with each other without conflict.
It should be noted that the drawings provided in the following embodiments are only for illustrating the basic idea of the present invention, and the components related to the present invention are only shown in the drawings rather than drawn according to the number, shape and size of the components in actual implementation, and the type, quantity and proportion of the components in actual implementation may be changed freely, and the layout of the components may be more complicated.
Example one
The embodiment provides a quality evaluation method of magnetocardiogram signals, which comprises the following steps:
preprocessing the collected MCG data for recording magnetocardiogram signals generated by the heart electrical activity;
identifying the R peak of a QRS wave in the preprocessed MCG data, and carrying out period segmentation on the preprocessed MCG data;
calculating a plurality of quality evaluation parameters associated with the MCG data to evaluate the quality of the magnetocardiogram signal based on the MCG data after the period division;
judging the grades of the quality evaluation parameters according to the evaluation threshold values of the quality evaluation parameters;
and evaluating the quality of the magnetocardiogram signal according to the grades of the plurality of quality evaluation parameters.
The magnetocardiogram signal quality evaluation method according to the present embodiment will be described in detail with reference to the drawings. Before the quality evaluation method of the magnetocardiogram signals according to the present embodiment is performed, it is necessary to acquire the magnetocardiogram signals for recording the electrical activity of the heart and the ECG data for recording the electrical signals generated by the electrical activity of the heart by the magnetocardiogram apparatus and the electrocardiograph apparatus, respectively. Fig. 1 is a schematic flow chart of a magnetocardiogram signal quality evaluation method according to an embodiment. As shown in fig. 1, the quality evaluation method of magnetocardiogram signals specifically includes the following steps:
s1, pre-processing the acquired MCG data for recording magnetocardiogram signals generated by the cardiac electrical activity and the ECG data for recording electrical signals generated by the cardiac electrical activity. Specifically, the MCG data acquired for recording the magnetocardiogram signals generated by the electrical activity of the heart and the ECG data acquired for recording the electrical signals generated by the electrical activity of the heart are subjected to 100Hz low pass filtering and 50Hz notching.
S2, identifying the R peak of the QRS wave in the preprocessed MCG data and ECG data. In this embodiment, the first differentiation, the nonlinear transformation, and the second differentiation are performed on the MCG data and the ECG data after the preprocessing, and a point other than 0 is selected from the second differentiation data result g' (n) and is represented as the R peak of the QRS wave. In this embodiment, identifying the R peak of the QRS wave is a calculation of cycle segmentation and quality assessment parameters for subsequent MCG data and ECG data.
And S3, carrying out cycle segmentation on the preprocessed MCG data. Please refer to fig. 2, which is a flowchart illustrating the step S3. As shown in fig. 2, the step S3 specifically includes the following steps:
s31, calculating average period of the preprocessed MCG data and ECG data(since one ECG data will correspond to one MCG data, the ECG data and MCG data averaging period are the same).
In this embodiment, the identified pre-processed MCG data andaverage period of ECG dataRtiIs the time corresponding to the ith R peak in the preprocessed MCG data/ECG data, Rti+1The time corresponding to the i +1 th R peak in the preprocessed MCG data/ECG data; n is a radical of1The number of R-waves in the identified pre-processed MCG data/ECG data. In this embodiment, the number of R-waves in the preprocessed MCG data is equal to the number of R-waves in the preprocessed ECG data.
And S32, taking the time corresponding to the R peak in the preprocessed MCG data and the ECG data as a reference point, taking 0.4 average cycles before the reference point and taking 0.6 average cycles after the reference point to respectively perform cycle segmentation on the preprocessed MCG data and the ECG data, recombining into a calculation cycle, and segmenting the preprocessed MCG data and the ECG data according to the calculation cycle.
S4, calculating a plurality of quality assessment parameters associated with the MCG data for assessing the quality of the magnetocardiogram signal based on the MCG data and the ECG data after the period division. In this embodiment, the quality assessment parameters further include quality assessment parameters associated with the MCG data and ECG data to assess quality of magnetocardiogram signals. Specifically, the quality evaluation parameters associated with the MCG data and the ECG data to evaluate quality of magnetocardiogram signals include an average correlation coefficient and an available Ratio of the MCG data and the ECG data preprocessed in each calculation cycle.
In the present embodiment, the average correlation coefficient of the preprocessed MCG data and ECG data is calculated for each calculation cycleComprises the following steps:
calculating absolute correlation coefficient | r of preprocessed MCG data and ECG data in each calculation periodiI is 1,2,3 … N, i is the serial number of the number of calculation cycles in the MCG data;
xj,j=1,2,3,...,M,xjthe method comprises the steps that MCG data in a calculation period are obtained, j is the serial number of the MCG data, and M is the total number of the MCG data in the calculation period;for MCG data x in one calculation periodjAverage value of (d); y isj,j=1,2,3,...,M,yjIs ECG data in a calculation period, and j is an ECG data serial number;is y in one cyclejAverage value of (d);
calculating the average correlation coefficient of the preprocessed MCG data and ECG data in all calculation periodsAnd N is the number of calculation cycles in the MCG data.
In this embodiment, the step of calculating the available proportion Ratio includes:
judging the absolute correlation coefficient | r of the preprocessed MCG data and the ECG data in each calculation period according to a judgment criterioniIf is good or bad, the judgment criterion isWherein, sigma is a threshold value for judging the good and bad correlation coefficient, and ziIs the result of the discrimination;
counting the number G of good absolute correlation coefficients of the preprocessed MCG data and the preprocessed ECG data in all calculation periods, and calculating the available proportionAnd N is the number of calculation cycles in the MCG data.
In this embodiment, the quality assessment parameters associated with the MCG data to assess quality of magnetocardiogram signals include pre-processingR variance of the MCG data, mean variance of the pre-processed MCG data, maximum variance of the pre-processed MCG data, mean signal-to-noise ratio of the pre-processed MCG dataAnd/or SNR of the preprocessed MCG datamin。
Specifically, the step of calculating the R variance of the preprocessed MCG data includes:
counting the variance R of R peaks of N calculation periods in the preprocessed MCG datavar,RiFor the ith R peak in the pre-processed MCG data,is the average of all R peaks.
The step of calculating the mean and maximum variance of the preprocessed MCG data comprises:
calculating the variance of QRS wave base values in a calculation period of the preprocessed MCG datai is 1,2,3 … N, which is the serial number of the calculated cycles in the MCG data; QRS wave base value B of preprocessed MCG data in one calculation periodjIs MCG data value within a preset base value time range, wherein the preset base value time range is T2-TMoment of start of cycle0.33T; wherein the content of the first and second substances,k is a base value BjThe number of the (c) is,is a base value BjAverage value of (a).
Variance of QRS wave base value in each calculation period according to preprocessed MCG dataCalculating the average base value variance of the preprocessed MCG data in all calculation periodsAnd the step of maximum variance of the basis values comprises:
calculating the average base value variance of the preprocessed MCG data in each calculation periodN is the number of calculation periods in MCG data;
the maximum base value variance of the preprocessed MCG data is the QRS base value variance in all calculation periodsIs measured.
Calculating average signal-to-noise ratio of preprocessed MCG dataAnd SNRminComprises the following steps:
calculating SNR of the preprocessed MCG data in each calculation periodiI is 1,2,3 … N, which is the serial number of the calculated cycles in the MCG data;Rifor the R peak value of the ith calculation cycle of the preprocessed MCG data,calculating the variance of the base value of the ith calculation period of the preprocessed MCG data;
according to SNR of the preprocessed MCG data in each calculation periodiCalculating the average signal-to-noise ratio of the preprocessed MCG data
After pretreatmentSNR of MCG dataminFor all SNR calculation periodsiIs measured.
And S5, judging the grades of the quality evaluation parameters according to the evaluation threshold values corresponding to the quality evaluation parameters. In this embodiment, the grades of the quality evaluation parameters include a first grade, a second grade, and a third grade, i.e., good, normal, and bad. Referring to table 1, a plurality of rating thresholds corresponding to the quality assessment parameters and an associated rating comparison table.
Table 1: a plurality of rating thresholds corresponding to the quality evaluation parameters and the corresponding grade comparison table
In this embodiment, the evaluation threshold values in table 1 are specifically shown in table 2.
Table 2: specific value of evaluation threshold
And S6, evaluating the quality of the magnetocardiogram signal according to the grades of the quality evaluation parameters. In this embodiment, the quality levels of the magnetocardiogram signals include a first level, a second level, and a third level, i.e., good quality level, normal quality level, and bad quality level. In the present embodiment, step S6 determines the level of magnetocardiogram signal quality by voting. Please refer to fig. 3, which is a flowchart illustrating the step S6. As shown in fig. 3, the step S6 includes:
s61, determining whether the number of quality evaluation parameters belonging to the first level is greater than the number threshold for indicating that the level of magnetocardiogram signal quality is the first level (in this embodiment, the number threshold indicating that the level of magnetocardiogram signal quality is superior is 4, or half of the total number of quality evaluation parameters); if so, it indicates that the quality level of the magnetocardiogram signal is the first level, otherwise, step S62 is executed to continuously determine whether the number of quality evaluation parameters belonging to the third level is greater than the number threshold for indicating that the level of the magnetocardiogram signal quality is the third level (in this embodiment, the number threshold for indicating that the level of the magnetocardiogram signal quality is poor is 4, or half of the total number of the quality evaluation parameters); if yes, the quality grade of the magnetocardiogram signal is represented as a third grade, and if no, the quality grade of the magnetocardiogram signal is represented as a second grade (the grade representing the quality of the magnetocardiogram signal is general). Please refer to fig. 4, which is a diagram illustrating the magnetocardiogram signals with different noise contents and the quality evaluation result. As shown in fig. 4, after the above evaluation, the quality level of the first magnetocardiogram signal is good, the level of the second magnetocardiogram signal is normal, and the level of the third magnetocardiogram signal is poor.
The quality evaluation method for the magnetocardiogram signals overcomes the defect that the existing signal quality evaluation method is not high in reliability in quality evaluation of the magnetocardiogram signals, and provides a reliable system and method suitable for quality evaluation of the magnetocardiogram signals. The invention comprehensively considers the magnetocardiogram signal characteristics, and proposes seven parameters from MCG and ECG data: the method has the advantages that the method comprises the steps of average correlation coefficient, the available proportion of MCG and ECG, R variance, average base value variance, maximum base value variance, average SNR, minimum SNR and the like of MCG, and utilizes a voting mode to give qualitative rating to the signal quality of MCG, so that the reliability of magnetocardiogram signal quality evaluation is improved, the operation speed is high, and the method can be applied to real-time analysis of the signal quality during MCG online acquisition.
Example two
Fig. 5 shows a schematic structural diagram of a quality evaluation system for magnetocardiogram signals in an embodiment. As shown in fig. 5, the magnetocardiogram signal quality evaluation system 1 includes: a preprocessing module 11, a recognition module 12, a segmentation module 13, a calculation module 14, and an evaluation module 15.
The preprocessing module 11 is used for preprocessing the acquired MCG data for recording magnetocardiogram signals generated by the cardiac electrical activity and the ECG data for recording electrical signals generated by the cardiac electrical activity. Specifically, the preprocessing module 11 performs 100Hz low-pass filtering and 50Hz notching on the collected MCG data for recording the magnetocardiogram signals generated by the cardiac electrical activity and the ECG data for recording the electrical signals generated by the cardiac electrical activity.
The identification module 12 connected to the preprocessing module 11 is used for identifying the R peak of the QRS wave in the preprocessed MCG data and ECG data. In this embodiment, the first differentiation, the nonlinear transformation, and the second differentiation are performed on the MCG data and the ECG data after the preprocessing, and a point other than 0 is selected from the second differentiation data result g' (n) and is represented as the R peak of the QRS wave. In this embodiment, identifying the R peak of the QRS wave is a calculation of cycle segmentation and quality assessment parameters for subsequent MCG data and ECG data.
And the segmentation module 13 connected with the identification module 12 is used for periodically segmenting the preprocessed MCG data. The splitting module 13 includes a first splitting unit 131 and a second splitting unit 132.
The first dividing unit 131 is specifically configured to:
calculating the average period of the preprocessed MCG data(since one ECG data will correspond to one MCG data, the ECG data and MCG data averaging period are the same).
Taking the time corresponding to the R peak in the pre-processed MCG data as a reference point, taking 0.4 period before the reference point and taking 0.6 period after the reference point, carrying out period division on the pre-processed MCG data, recombining into a calculation period, and dividing the pre-processed MCG data according to the calculation period.
The second dividing unit 132 is specifically configured to:
calculating an average period of the pre-processed ECG data(since one ECG data corresponds to one MCG data, the ECG data and the MCG dataThe data averaging period is the same).
In this embodiment, the identified average period of the pre-processed MCG data and ECG dataRtiIs the time corresponding to the ith R peak in the preprocessed MCG data/ECG data, Rti+1The time corresponding to the i +1 th R peak in the preprocessed MCG data/ECG data; n is a radical of1The number of R-waves in the identified pre-processed MCG data/ECG data. In this embodiment, the number of R-waves in the preprocessed MCG data is equal to the number of R-waves in the preprocessed ECG data.
Taking the time corresponding to the R peak in the identified preprocessed MCG data as a reference point, taking 0.4 average cycles before the reference point, and taking 0.6 average cycles after the reference point, so as to perform cycle segmentation on the preprocessed and ECG data, and recombining into a calculation cycle, and segmenting the preprocessed ECG data according to the calculation cycle.
The computation module 14 connected to the segmentation module 13 is configured to compute a plurality of quality assessment parameters associated with the MCG data to assess quality of magnetocardiogram signals based on the MCG data after the period segmentation. In this embodiment, the quality assessment parameters further include quality assessment parameters associated with the MCG data and ECG data to assess quality of magnetocardiogram signals. Specifically, the quality evaluation parameters associated with the MCG data and the ECG data to evaluate quality of magnetocardiogram signals include an average correlation coefficient and an available Ratio of the MCG data and the ECG data preprocessed in each calculation cycle. In the present embodiment, the calculating module 14 includes a first calculating unit 141, a second calculating unit 142, a third calculating unit 143, a fourth calculating unit 144, a fifth calculating unit 145, a sixth calculating unit 146, and a seventh calculating unit 147.
In this embodiment, the first calculating unit 141 connected to the second dividing unit 132 is used for calculating the average correlation coefficient of the preprocessed MCG data and ECG data in each calculating periodThe specific calculation process is as follows:
calculating absolute correlation coefficient | r of preprocessed MCG data and ECG data in each calculation periodiI is 1,2,3 … N, i is the serial number of the number of calculation cycles in the MCG data;
xjj is 1,2, 3., M is the serial number of the MCG data in one calculation period, and M is the total number of the MCG data in one calculation period;for MCG data x in one calculation periodjAverage value of (d); y isjJ is 1,2, 3.. M is the serial number of the ECG data in one calculation cycle;is y in one cyclejAverage value of (d);
calculating the average correlation coefficient of the preprocessed MCG data and the ECG data in each calculation periodAnd N is the number of calculation cycles in the MCG data.
In this embodiment, the second calculating unit 142 is configured to calculate the available Ratio, and the specific calculation process is as follows:
judging the absolute correlation coefficient | r of the preprocessed MCG data and the ECG data in each calculation period according to a judgment criterioniIf is good or bad, the judgment criterion isWherein, sigma is a threshold value for judging the good and bad correlation coefficient, and ziIs the result of the discrimination;
counting the preprocessed M in all computing periodsThe number G of good absolute correlation coefficients between CG data and ECG data, and the available ratio is calculatedAnd N is the number of calculation cycles in the MCG data.
In the embodiment, the quality evaluation parameters associated with the MCG data for evaluating the quality of magnetocardiogram signals include R variance of the preprocessed MCG data, mean variance of the basis values of the preprocessed MCG data, maximum variance of the basis values of the preprocessed MCG data, and mean signal-to-noise ratio of the preprocessed MCG dataAnd/or SNR of the preprocessed MCG datamin。
Specifically, the third calculating unit 143 is configured to calculate an R variance of the preprocessed MCG data. The specific calculation process comprises the following steps:
counting the variance R of R peaks of N calculation periods in the preprocessed MCG datavar,RiFor the ith R peak in the pre-processed MCG data,is the average of all R peaks.
The step of calculating the mean and maximum variance of the preprocessed MCG data comprises:
calculating the variance of QRS wave base values in a calculation period of the preprocessed MCG datai is 1,2,3 … N, which is the serial number of the calculated cycles in the MCG data; QRS wave base value B of preprocessed MCG data in one calculation periodjIs MCG data value within a preset base value time range, wherein the preset base value time range is T2-TMoment of start of cycle0.33T; wherein the content of the first and second substances,k is a base value BjThe number of the (c) is,is a base value BjAverage value of (a).
The fourth calculating unit 144 and the fifth calculating unit 145 are used for calculating the variance of the QRS base value in one calculating period according to the preprocessed MCG dataCalculating the average base value variance of the preprocessed MCG data in each calculation periodAnd a maximum variance of the contributions.
The specific calculation process of the fourth calculation unit 144 includes:
calculating the average base value variance of the preprocessed MCG data in each calculation periodN is the number of calculation periods in MCG data;
the fifth calculating unit 145 is configured to select the maximum variance of the base values of the preprocessed MCG data as the variance of the QRS base values in all calculating periodsIs measured.
The sixth calculating unit 146 and the seventh calculating unit 147 are used for calculating the average signal-to-noise ratio of the preprocessed MCG dataAnd SNRmin. The specific calculation process of the sixth calculation unit 146 includes:
calculating SNR of the preprocessed MCG data in each calculation periodiI is 1,2,3 … N, which is the serial number of the calculated cycles in the MCG data;Rifor the R peak value of the ith calculation cycle of the preprocessed MCG data,calculating the variance of the base value of the ith calculation period of the preprocessed MCG data;
according to SNR of the preprocessed MCG data in each calculation periodiCalculating the average signal-to-noise ratio of the preprocessed MCG data
The seventh calculating unit 147 is used for selecting SNR of the preprocessed MCG dataminFor all SNR calculation periodsiIs measured.
The evaluation module 15 connected to the calculation module 14 is configured to determine the grades of the quality evaluation parameters according to a plurality of rating threshold values corresponding to the quality evaluation parameters. In this embodiment, the grades of the quality evaluation parameters include a first grade, a second grade, and a third grade, i.e., good, normal, and bad. The evaluation module 15 is further configured to evaluate quality of the magnetocardiogram signal according to the grade of the plurality of quality evaluation parameters. In this embodiment, the quality levels of the magnetocardiogram signals include a first level, a second level, and a third level, i.e., good quality level, normal quality level, and bad quality level.
The embodiment further provides a server 2, the server 2 is connected to the electrocardiograph and the magnetocardiogram apparatus, please refer to fig. 6, which is a schematic diagram of a schematic structure of the server in an embodiment. As shown in fig. 6, the server 2 includes the magnetocardiogram signal quality evaluation system 1.
In summary, the magnetocardiogram signal quality evaluation method, system and server provided by the invention overcome the defect of low reliability of the existing signal quality evaluation method for evaluating magnetocardiogram signal quality, and provide a reliable system and method suitable for magnetocardiogram signal quality evaluation. The invention comprehensively considers the magnetocardiogram signal characteristics, and proposes seven parameters from MCG and ECG data: the method has the advantages that the method comprises the steps of average correlation coefficient, the available proportion of MCG and ECG, R variance, average base value variance, maximum base value variance, average SNR, minimum SNR and the like of MCG, and utilizes a voting mode to give qualitative rating to the signal quality of MCG, so that the reliability of magnetocardiogram signal quality evaluation is improved, the operation speed is high, and the method can be applied to real-time analysis of the signal quality during MCG online acquisition. Therefore, the invention effectively overcomes various defects in the prior art and has high industrial utilization value.
The foregoing embodiments are merely illustrative of the principles and utilities of the present invention and are not intended to limit the invention. Any person skilled in the art can modify or change the above-mentioned embodiments without departing from the spirit and scope of the present invention. Accordingly, it is intended that all equivalent modifications or changes which can be made by those skilled in the art without departing from the spirit and technical spirit of the present invention be covered by the claims of the present invention.
Claims (9)
1. A quality evaluation method for magnetocardiogram signals is characterized by comprising the following steps:
preprocessing the collected MCG data and ECG data for recording the magnetocardiogram signals generated by the heart electrical activity;
identifying R peaks of QRS waves in the preprocessed MCG data and the ECG data, and carrying out period segmentation on the preprocessed MCG data;
calculating a plurality of quality evaluation parameters associated with the MCG data and the ECG data for evaluating quality of magnetocardiogram signals based on the MCG data and the ECG data after cycle segmentation; the quality assessment parameters associated with the MCG data and ECG data comprise average correlation coefficients of the pre-processed MCG data and ECG data; wherein the average correlation coefficient of the preprocessed MCG data and ECG data is calculatedComprises the following steps:
calculating absolute correlation coefficient | r of preprocessed MCG data and ECG data in each calculation periodiI is 1,2,3 … N, i is the serial number of the number of calculation cycles in the MCG data;
wherein x isj,j=1,2,3,...,M,xjThe method comprises the steps that MCG data in a calculation period are obtained, j is the serial number of the MCG data, and M is the total number of the MCG data in the calculation period;for MCG data x in one calculation periodjAverage value of (d); y isj,j=1,2,3,...,M,yjIs ECG data in a calculation cycle, j is the serial number of the ECG data;is y in one cyclejAverage value of (d);
calculating the average correlation coefficient of MCG data and ECG data of all calculation periods after preprocessingN is the total number of calculation periods in MCG data;
judging the grades of the quality evaluation parameters according to a plurality of evaluation threshold values corresponding to the quality evaluation parameters;
and evaluating the quality of the magnetocardiogram signal according to the grades of the plurality of quality evaluation parameters.
2. The magnetocardiogram signal quality evaluation method according to claim 1, wherein: the step of performing a periodic segmentation of the preprocessed MCG data and ECG data comprises:
calculating an average period of the preprocessed MCG data and ECG data; the identified average period of the pre-processed MCG data and ECG dataRtiIs the time corresponding to the ith R peak in the preprocessed MCG data/ECG data, Rti+1The time corresponding to the i +1 th R peak in the preprocessed MCG data/ECG data; n is a radical of1The number of the identified R waves in the preprocessed MCG data/ECG data;
taking the time corresponding to the R peak in the identified preprocessed MCG and ECG data as a reference point, taking 0.4 average cycles before the reference point, and taking 0.6 average cycles after the reference point, so as to respectively perform cycle segmentation on the preprocessed MCG data and the ECG data to form a computing cycle, and segmenting the preprocessed MCG data and the ECG data according to the computing cycle.
3. The magnetocardiogram signal quality evaluation method according to claim 1, wherein: the quality assessment parameters associated with the MCG data and ECG data further comprise an available Ratio; the step of calculating the available proportion Ratio includes:
judging the absolute correlation coefficient | r of the preprocessed MCG data and the ECG data in each calculation period according to a judgment criterioniIf is good or bad, the judgment criterion isWherein, sigma is a threshold value for judging the good and bad correlation coefficient, and ziIs the result of the discrimination;
4. The magnetocardiogram signal quality evaluation method according to claim 1, wherein: the quality assessment parameters associated with the MCG data further include an R variance of the pre-processed MCG data;
the step of calculating the R variance of the preprocessed MCG data comprises:
5. The magnetocardiogram signal quality evaluation method according to claim 1, wherein: the quality assessment parameters associated with the MCG data further comprise a mean variance and a maximum variance of the preprocessed MCG data;
the step of calculating the mean and maximum variance of the preprocessed MCG data comprises:
calculating the variance of QRS wave base values in a calculation period of the preprocessed MCG dataCalculating the serial number of the periods in the MCG data; QRS wave base value B of preprocessed MCG data in one calculation periodjIs MCG data value in a preset base value time range, wherein the preset base value time range is from one period starting time to 0.33T, and T is a calculation period; wherein the content of the first and second substances,k is a base value BjThe number of the (c) is,is a base value BjAverage value of (d);
according to the variance of the QRS wave base value in a calculation period of the preprocessed MCG dataCalculating the average base value variance of the preprocessed MCG data in all calculation periodsAnd a maximum variance of the contributions; wherein the mean variance of the contributionsN is the number of calculation periods in MCG data;
6. The magnetocardiogram signal quality evaluation method according to claim 1, wherein: the quality assessment parameters associated with the MCG data further include an average signal-to-noise ratio of the pre-processed MCG dataAnd SNRmin;
Calculating average signal-to-noise ratio of preprocessed MCG dataAnd SNRminComprises the following steps:
calculating the SNR of the preprocessed MCG data in each calculation periodiI is 1,2,3 … N, which is the serial number of the calculated cycles in the MCG data;Rifor the R peak value of the ith calculation cycle of the preprocessed MCG data,calculating the variance of the base value of the ith calculation period of the preprocessed MCG data;
according to SNR of the preprocessed MCG data in each calculation periodiCalculating the average signal-to-noise ratio of the preprocessed MCG data
SNR of preprocessed MCG dataminFor all SNR calculation periodsiIs measured.
7. The magnetocardiogram signal quality evaluation method according to claim 1, wherein: the grades of the quality evaluation parameters comprise a first grade, a second grade and a third grade; the levels of magnetocardiogram signal quality include a first level, a second level, and a third level; the step of evaluating the quality of the magnetocardiogram signal according to the grade of the plurality of quality evaluation parameters comprises the following steps:
judging whether the number of the quality evaluation parameters belonging to the first level is larger than a number threshold value of the level for representing the quality of the magnetocardiogram signal as the first level; if so, indicating that the quality grade of the magnetocardiogram signal is a first grade, and if not, continuously judging whether the number of the quality evaluation parameters belonging to a third grade is larger than a threshold value of the number for indicating that the grade of the quality of the magnetocardiogram signal is the third grade; if yes, the quality grade of the magnetocardiogram signal is represented as a third grade, and if not, the quality grade of the magnetocardiogram signal is represented as a second grade.
8. A magnetocardiogram signal quality evaluation system, comprising:
the preprocessing module is used for preprocessing the acquired MCG data and ECG data for recording the magnetocardiogram signals generated by the cardiac electrical activity;
the segmentation module is used for identifying the R peak of the QRS wave in the preprocessed MCG data and the ECG data and carrying out periodic segmentation on the preprocessed MCG data;
computing module for basisCalculating a plurality of quality evaluation parameters which are related to the MCG data and used for evaluating the quality of the magnetocardiogram signals in the MCG data and the ECG data after the period division; the quality assessment parameters associated with the MCG data and ECG data comprise average correlation coefficients of the pre-processed MCG data and ECG data; wherein the calculation module calculates an absolute correlation coefficient | r of the preprocessed MCG data and the ECG data in each calculation cycleiI is 1,2,3 … N, i is the serial number of the number of calculation cycles in the MCG data;
wherein x isj,j=1,2,3,...,M,xjThe method comprises the steps that MCG data in a calculation period are obtained, j is the serial number of the MCG data, and M is the total number of the MCG data in the calculation period;for MCG data x in one calculation periodjAverage value of (d); y isj,j=1,2,3,...,M,yjIs ECG data in a calculation cycle, j is the serial number of the ECG data;is y in one cyclejAverage value of (d);
calculating the average correlation coefficient of MCG data and ECG data of all calculation periods after preprocessingN is the total number of calculation periods in MCG data;
the evaluation module is used for judging the grades of the quality evaluation parameters according to the evaluation threshold values of the quality evaluation parameters; and evaluating the quality of the magnetocardiogram signal according to the grades of the plurality of quality evaluation parameters.
9. A server, characterized by comprising a magnetocardiogram signal quality evaluation system as claimed in claim 8.
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