CN107737051A - A kind of facial mask for promoting skin metabolism - Google Patents

A kind of facial mask for promoting skin metabolism Download PDF

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Publication number
CN107737051A
CN107737051A CN201711239622.XA CN201711239622A CN107737051A CN 107737051 A CN107737051 A CN 107737051A CN 201711239622 A CN201711239622 A CN 201711239622A CN 107737051 A CN107737051 A CN 107737051A
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China
Prior art keywords
skin
facial mask
salt lake
nicotinic acid
cactus pedicel
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CN201711239622.XA
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Chinese (zh)
Inventor
林俊浩
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Individual
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Individual
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Priority to CN201711239622.XA priority Critical patent/CN107737051A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/965Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of facial mask for promoting skin metabolism, it includes the composition of following mass percent:The smooth stearate 0.2~2% of nicotinic acid 0.4~2.5%, salt lake black mud 1~15%, Cactus Pedicel extract 5~10%, microwax 1~2%, Dormant oils 0.1~0.3%, ethylhexyl palmitate 1~4%, vaseline 5~10%, beeswax 0.5~2.5%, volcanic mud 7~10%, sorb, methyl hydroxybenzoate 0.1~0.2%, Butylated Hydroxytoluene 0.02~0.2%, deionized water surplus.Long-term use of facial mask can reduce the deposition of heavy metal in skin, slow down skin heavy metal poisoning symptom, Skin Cell normal growth, cutaneous respiration and skin metabolism can also be promoted simultaneously, effectively play antioxidation, delaying skin aging, and multiple moisture-keeping efficacy, skin is kept to moisten, reach beauty treatment, repair the purpose of skin.

Description

A kind of facial mask for promoting skin metabolism
Technical field
The present invention relates to cosmetic field, and in particular to a kind of facial mask for promoting skin metabolism.
Background technology
Facial mask is the thin film applied on skin, and it is by skin and extraneous air exclusion that it, which is acted on, makes skin temperature Rise, in allowing the nutriment being attached on facial mask to penetrate to the skin, play a part of promoting skin function.Prior art In, to increase the performances such as gas permeability, adsorptivity and the adjustable wet of facial mask, mainly by adding synthetics, have to skin Certain side effect, it is impossible to long-term use of.Existing facial mask effect is single simultaneously, is mostly moisturizing, white-skinned face function, without pair The repairing effect of skin, it is impossible to meet the needs of people.Therefore, exploitation one kind both has Glycerin, can promote skin again The facial mask of metabolism, anti-aging and other effects more will be liked by people.
The content of the invention
Based on this, it is an object of the invention to provide a kind of facial mask for promoting skin metabolism.
To achieve the above object, specifically adopt the following technical scheme that:
A kind of facial mask for promoting skin metabolism contains three kinds of nicotinic acid, salt lake black mud, Cactus Pedicel extract compositions, and Mass percent is:
Nicotinic acid:0.4~2.5%
Salt lake black mud:1~15%
Cactus Pedicel extract:5~10%.
Preferably, described nicotinic acid, salt lake black mud, the mass percent of Cactus Pedicel extract are as follows:
Nicotinic acid:0.8~1.8%
Salt lake black mud:3~10%
Cactus Pedicel extract:7~8%.
Optimal, described nicotinic acid, salt lake black mud, the mass percent of Cactus Pedicel extract are as follows:
Nicotinic acid:1.3%
Salt lake black mud:7%
Cactus Pedicel extract:7.5%.
Further, the sludge that described salt lake black mud is gathered by Yuncheng Salt Lake.
Further, described Cactus Pedicel extract is prepared as follows:
1) geranium wilfordii is crushed, the alcohol reflux of 7 times of amounts extracts 3 times, merges extract solution and further concentrates, obtains once Extract concentrate;
2) it is dissolved in water after concentrate, reuses organic solvent extraction, then secondary raffinate is concentrated to dryness, obtained Second extraction concentrate;
3) successively with chloroform, chloroform:Methanol=10:1st, chloroform:Methanol=8:1st, chloroform:Methanol=5:1 pair of second extraction Concentrate carries out column chromatography elution separation, then collects chloroform:Methanol=5:1 eluent is simultaneously concentrated to dryness, and obtains cactus Stem extraction.
Further, the facial mask of described promotion skin metabolism also includes the composition of following mass percent:Crystallite Wax 1~2%, Dormant oils 0.1~0.3%, ethylhexyl palmitate 1~4%, vaseline 5~10%, beeswax 0.5~2.5%, volcano The smooth stearate 0.2~2% of mud 7~10%, sorb, methyl hydroxybenzoate 0.1~0.2%, Butylated Hydroxytoluene 0.02~0.2%, go from Sub- water surplus.
Several compositions in the present invention are introduced below:
Salt Lake In Yuncheng Region of Shanxi rich in mineral resources, rich in needed by human body in the black mud of salt lake water particularly lake bed deposits The mineral matter such as potassium, sodium, calcium, magnesium, iron, chlorine, iodine, bromine and sulfate and carbonate and trace element.Salt lake black mud also contains algae The remains of the animals and plants such as class, pasture and water and shell-fish, by depositing for many years, form the protein beneficial to human body skin, amino acid With the organic substance such as polysaccharide.The mineral matter and trace element that salt lake black mud contains are biochemical reaction and physiological function activity in human body Required nutrient, they are multiple functions enzyme system and the main component of protein system, simultaneously participate in nervous activity and The regulation of permeability of cell membrane.On Skin Cell normal growth, cutaneous respiration and skin metabolism is promoted, trace element Play an important role.Trace element zinc, copper, iron and selenium in black mud etc., which can provide, makes skin maintain vigour necessary element, Energy circulation can be promoted.Mineral matter element moisturizing due to its hygroscopic feature, can if Skin Cell absorbs mineral matter To improve the water capacity of cell interior.Salt lake black mud contains 30 several mineral materials, trace element and the activity beneficial to human body skin The organic substances such as fulvic acid, amino acid and vitamin E.It is super in these mineral matters, trace element and organic mass-energy enhancing skin The activity of Superoxide dismutase (SOD), glutathione peroxidase (GSH), both enzymes can be removed effectively on skin Unnecessary free radical, delay skin aging.
Nicotinic acid scientific name is Nicotinicum Acidum, also known as Buddhist nun gram butyric acid (niotiniCaeid, niaeid), niacin or nicotine Acid, abbreviation VB5、VppOr NA, it is stable in the air, it is nonhygroscopic;Toxicity is very micro-, LD50=3,500 one 7000mg/kg (mouse mouths Clothes), it is that structure is most simple, a kind of most stable of vitamin of physicochemical property, is indispensable nutritional ingredient in human body and animal, It participates in the oxidation-reduction process of tissue, with the function of promoting cell metabolism and expansion blood vessel, can promote human body and move Thing grows.Nicotinic acid has promotion cell metabolism, expands blood vessel, including expands myelencephalon blood vessel and promote the nephremia to make With, also have alleviate peripheral vessel spasm effect.
It is the device have the advantages that as follows:Facial mask of the present invention is mainly by nicotinic acid, salt lake black mud, Cactus Pedicel extract Form in specific proportions, toxin expelling is carried out by nicotinic acid, and various heavy can be adsorbed, while salt lake black mud and can enough promotees Enter Skin Cell normal growth, cutaneous respiration and skin metabolism, delaying skin aging, and it has hygroscopicity and sent out again Moisture-keeping function is waved, improves the water capacity of cell interior;The antioxidation of Cactus Pedicel extract can effectively remove freedom simultaneously Base, additionally it is possible to harmful heavy metal ions are reduced, so as to have the function that to promote the skin of skin metabolism.Long-term use of face Film can reduce the deposition of heavy metal in skin, slow down skin heavy metal poisoning symptom, while Skin Cell can also be promoted normal Growth, cutaneous respiration and skin metabolism, effectively play antioxidation, delaying skin aging, and multiple moisture-keeping efficacy, Keep skin to moisten, reach beauty treatment, repair the purpose of skin.
Embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated:
The facial mask embodiment 1~5 of the present invention is formulated, and is shown in Table 1.
Table 1
1st, the sludge that described salt lake black mud of the invention is gathered by Yuncheng Salt Lake.
2nd, the preparation method of Cactus Pedicel extract of the invention is as follows:
1) Cactus Pedicel is crushed, the alcohol reflux of 7 times of amounts extracts 3 times, merges extract solution and further concentrates, obtains one Secondary extraction concentrate;
2) it is dissolved in water after concentrate, reuses organic solvent extraction, then secondary raffinate is concentrated to dryness, obtained Second extraction concentrate;
3) successively with chloroform, chloroform:Methanol=10:1st, chloroform:Methanol=8:1st, chloroform:Methanol=5:1 pair of second extraction Concentrate carries out column chromatography elution separation, then collects chloroform:Methanol=5:1 eluent is simultaneously concentrated to dryness, and obtains cactus Stem extraction.
Comparative example 1:
Difference with embodiment 3 is only to be free of nicotinic acid, and remaining each group material addition, preparation does not change with technique.
Comparative example 2:
Difference with embodiment 3 is only that not salt lake black mud, the addition of remaining each group material, preparation do not change with technique Become.
Comparative example 3:
Difference with embodiment 3 is only to be free of Cactus Pedicel extract, and remaining each group material addition, preparation is not sent out with technique It is raw to change.
Comparative example 4:
Difference with embodiment 3 is only without 3 kinds of nicotinic acid, salt lake black mud and Cactus Pedicel extract compositions, remaining each group Material adds, and preparation does not change with technique.
Efficacy validation
Adsorb heavy metal checking:
The effect of in order to verify facial mask of the present invention, choose embodiment 1~5 and comparative example 1~4 carries out evaluation test on probation.
1st, object is tried out:Trier's health is all right, without lactation or pregnancy period, shows as face after heavy metal poisoning The crowd of portion's allergy, inflammation.
2nd, embodiment is as follows:Every group of 25 people are chosen to be tested.Product 22- every night corresponding to experimenter's use Using corresponding trial target between 24 points, each sampling phase is one month, and at the 30th day, experimenter was to adsorbing heavy metal Effect carries out self-appraisal, and self-appraisal is carried out to the cleaning action of adsorbed film;Contained before on probation with skinanalysis apparatus detection skin heavy metal Content of beary metal is detected when amount was with the 30th day;Whole people complete whole experiment during experiment, and require that everyone is honest Result of the test is reported, other any skin-protection products must not be used in experimentation.
3rd, evaluation criterion:It is effective to refer to that product allergic symptom is cured or cured close to healing state, inflammation;Effectively referred to Quick improvement, inflammation tend to improve;It is invalid to refer to that skin condition improve, or even aggravate.
4th, using the clinical evaluation of skin quality, the result of the test such as table 2 below of heavy metal is adsorbed;Product beta test evaluation test As a result such as table 3 below.
Table 2
As shown in Table 2, after product of the invention is used 30 days, the test of skin detection instrument substantially subtracts to skin heavy metal Few, skin toxins are reduced, and embodiment 1-5 product has the absorption heavy metal characteristic of conspicuousness relative to comparative example 1-4, and with The adsorption effect of embodiment 3 is optimal.
Table 3
As can be seen from Table 3, face's allergy, the skin problem of inflammation that product heavy metal poisoning of the present invention triggers have bright Aobvious improvement result, can effective toxin expelling, promote skin revitalization;In addition, the experimenter for having more than 95% thinks facial mask of the invention With excellent deep layer cleaning skin effect, the health status of skin can be maintained.
Anti-aging is verified:
Tested crowd:The voluntary tester of selection 100 30-40 year is divided into 10 groups, it is desirable to which experimenter is without others Skin disease, without allergic history.
Instrument:German CK companies skin elasticity tester MPA580
Method:Constant negative pressure pattern is selected, everyone tests one group of data, takes 10 to be worth for each person.30min after skin cleaning Tested, subject adheres to using above-mentioned trial target every night, respectively test be not used when be skip test, using 2 weeks, Skin elasticity and moisture-holding capacity after 4 weeks, subject simultaneously carry out self-appraisal to skin condition.Elastic index explanation:R2, R5, R7 are closer 1, R6 closer to 0, and the elasticity of skin is better.Water content test specification:Skin moisture content scope is classified:0-33 to be water deficient, 33-66 is normal, and 66-99 is that moisture is full.
Test result such as table 4 below and table 5:
Table 4
As shown in Table 4:Significantly increased using skin R2, R5, R7 numerical value after embodiment 1-5 facial mask the 2nd week and the 4th week Adding, its index levels off to 1, R6 reductions after the 4th week, and its exponential approach is in 0 after the 4th week, and uses comparative example 1-4 skin R2, R5, R7 ascensional range reduce amplitude with R6 and are significantly less than embodiment 1-5, and its using effect is not so good as embodiment, illustrates the present invention Facial mask can promote the metabolism of skin, make skin more flexible.
Table 5
As shown in Table 5:It is obvious using skin water content after embodiment 1-5 and comparative example 1-3 facial mask the 2nd week and the 4th week Improve, and embodiment is more excellent than comparative example and control group effect, illustrates that the present invention has good replenishing water and preserving moisture effect, makes flesh Skin more water is tender, fine and smooth.
Anti-oxidation efficacy is verified:
Test method:Remove the electronic paramagnetic resonance spectrometer experiment of hydroxyl radical free radical
At room temperature, in 4ml test tubes, phosphate buffer (pH 7.4) 0.5ml is sequentially added, 5 μ L 5,5- dimethyl- 1- pyrrolin-N oxides (DMP0), 250 μ L0.1M H202, face made from 1.5ml 0.1mM embodiments 1-5 and comparative example 1-4 Film, at the same using it is a it is commercially available declare to have good anti-oxidant face mask as control group, 250 μ L3mMFeS04 solution, in 6 minutes left sides ESR detections are carried out in right injection quartz capillary.As a result such as table 6 below.
Table 6
It was found from upper table data, 1-5 of embodiment of the present invention facial mask has very strong anti-oxidant to free radical compositions Activity, free radical can be removed in time, product is shown antioxidant effect.Above example is merely to illustrate the implementation of the present invention Scheme, there is not any formal limitation to the present invention;It is any to be engaged in professional and technical personnel, all have the ability using The technology contents of announcement, some are made to it and changes or modifies, turns into the equivalent embodiment of equivalent variations.According to the technology of the present invention Essence, simple modification, equivalent change and modification is carried out to the present invention, belonged in the range of technical solution of the present invention.

Claims (6)

1. a kind of facial mask for promoting skin metabolism, it is characterised in that contain nicotinic acid, salt lake black mud, Cactus Pedicel extract Three kinds of compositions, and mass percent is:
Nicotinic acid:0.4~2.5%
Salt lake black mud:1~15%
Cactus Pedicel extract:1~4%.
2. a kind of facial mask for promoting skin metabolism according to claim 1, it is characterised in that described nicotinic acid, salt Lake black mud, the mass percent of Cactus Pedicel extract are as follows:
Nicotinic acid:0.8~1.8%
Salt lake black mud:3~10%
Cactus Pedicel extract:2~3%.
3. a kind of facial mask for promoting skin metabolism according to claim 2, it is characterised in that described nicotinic acid, salt Lake black mud, the mass percent of Cactus Pedicel extract are as follows:
Nicotinic acid:1.3%
Salt lake black mud:7%
Cactus Pedicel extract:2.5%.
4. the facial mask of a kind of promotion skin metabolism according to any one of claims 1 to 3, it is characterised in that described The sludge that is gathered by Yuncheng Salt Lake of salt lake black mud.
5. the facial mask of a kind of promotion skin metabolism according to any one of claims 1 to 3, it is characterised in that described Cactus Pedicel extract be prepared as follows:
1) Cactus Pedicel is crushed, the alcohol reflux of 7 times of amounts extracts 3 times, merges extract solution and further concentrates, is once carried Take concentrate;
2) it is dissolved in water after concentrate, reuses organic solvent extraction, then secondary raffinate is concentrated to dryness, obtained secondary Extract concentrate;
3) successively with chloroform, chloroform:Methanol=10:1st, chloroform:Methanol=8:1st, chloroform:Methanol=5:1 pair of second extraction concentration Liquid carries out column chromatography elution separation, then collects chloroform:Methanol=5:1 eluent is simultaneously concentrated to dryness, and is obtained Cactus Pedicel and is carried Take thing.
6. the facial mask of a kind of promotion skin metabolism according to any one of Claims 1 to 5, it is characterised in that described The facial mask of promotion skin metabolism also include the composition of following mass percent:Microwax 1~2%, Dormant oils 0.1~ 0.3%th, ethylhexyl palmitate 1~4%, vaseline 5~10%, beeswax 0.5~2.5%, volcanic mud 7~10%, sorb are smooth hard Resin acid ester 0.2~2%, methyl hydroxybenzoate 0.1~0.2%, Butylated Hydroxytoluene 0.02~0.2%, deionized water surplus.
CN201711239622.XA 2017-11-30 2017-11-30 A kind of facial mask for promoting skin metabolism Pending CN107737051A (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1528264A (en) * 2003-10-16 2004-09-15 邵鲁安 Black mud for producing beauty, thinning and skin-care articles
CN101156832A (en) * 2007-09-25 2008-04-09 南风化工集团股份有限公司 A mineral black mud acne-dispelling face pack and its preparation method
CN101985434A (en) * 2010-11-12 2011-03-16 安徽泰格生物技术股份有限公司 Method for preparing nicotinic acid

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1528264A (en) * 2003-10-16 2004-09-15 邵鲁安 Black mud for producing beauty, thinning and skin-care articles
CN101156832A (en) * 2007-09-25 2008-04-09 南风化工集团股份有限公司 A mineral black mud acne-dispelling face pack and its preparation method
CN101985434A (en) * 2010-11-12 2011-03-16 安徽泰格生物技术股份有限公司 Method for preparing nicotinic acid

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Application publication date: 20180227