CN107736946A - A kind of portable digital temperature control scald apparatus - Google Patents
A kind of portable digital temperature control scald apparatus Download PDFInfo
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- CN107736946A CN107736946A CN201710943082.7A CN201710943082A CN107736946A CN 107736946 A CN107736946 A CN 107736946A CN 201710943082 A CN201710943082 A CN 201710943082A CN 107736946 A CN107736946 A CN 107736946A
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- 206010053615 Thermal burn Diseases 0.000 title claims abstract description 116
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- 238000010171 animal model Methods 0.000 claims abstract description 11
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D1/00—Surgical instruments for veterinary use
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Toys (AREA)
Abstract
The present invention relates to a kind of portable digital temperature control scald apparatus, particularly useful for making standardized laboratory animals skin scald model, mainly first-class form is scalded by scald apparatus main body, the microcomputer temperature controller, temperature sensor, electronic digital counter, buzzer and master control electric elements and silicon rubber heater, replaceable Quick Release.Perm temperature and scald time parameter needed for being set using intelligent microcomputer temperature controller and electronic digital timer, permed with the heating of silicon rubber electric heater and by temperature sensor by real time temperature data transfer to the microcomputer temperature controller.When temperature exceedes the design temperature upper limit, stop heating, while start radiator fan, reduce scald head temperature；When temperature is less than design temperature lower limit, start heating.This automation degree of equipment height, temperature-controlled precision height, accurate timing, compact-sized, compact, it is easy to carry, scald is replaceable, suitable for the animal skin scalding model such as mouse, rat, rabbit, miniature pig.
Description
Technical field
The invention belongs to Life Science Experiment Instrument technology field, more particularly to a kind of portable digital temperature control scald
Instrument.
Background technology
At present, prepare animal skin scalding model and lack standardization scald laboratory apparatus or equipment, the scald reported is real
Testing instrument and method has：(1) scald animal model is established by the use of hospital gauze as heat carrier；(2) high steam scald apparatus；
(3) make flatiron by oneself and establish scald animal model as heat carrier；(4) desk-top temperature control scald apparatus etc. is made by oneself, these scald experiment instruments
Device and method exist experimental result standard differs, repeatability is poor, temperature control is inaccurate, equipment volume is big, carry and operation
In place of the deficiencies of inconvenient.
The content of the invention
The shortcomings that in order to overcome above-mentioned prior art, it is an object of the invention to provide a kind of portable digital temperature control to scald
Hinder instrument, particularly useful for making standardized laboratory animals skin scald model, be favorably improved experimental skin scald mechanism and
The research level of prophylactico-therapeutic measures.
To achieve these goals, the technical solution adopted by the present invention is：
A kind of portable digital temperature control scald apparatus, pistol layout architecture is similar to using compact, scald apparatus main body by
Function part and Handheld Division composition, the rear end of function part is connected with Handheld Division.The front end installation Quick Release stainless steel of the function part scalds
Hinder head, NTC thermistor type temperature sensor 5 is installed on the connector of Quick Release stainless steel scald head, it is in close contact scald
Head.The stainless steel heat transfer axle for being wound with silicon rubber electric heater is closely connected in the rear end of connector, in the rear installation of heat transfer axle
Radiator fan.Install instruments cabin at the top of function part, installed in cabin intelligent microcomputer temperature controller, electronic digital timer and
Alarm buzzer.Installation power switch in Handheld Division and function part junction, power line are drawn from the bottom of Handheld Division, connection
220v power outlets.Silicon rubber electric heater, radiator fan, electronic digital timer and alarm buzzer use electric wire and intelligence respectively
Can the microcomputer temperature controller connection.
The device model TR-WK-08 of the intelligent microcomputer temperature controller.
The function part face heat transfer shaft rear end is provided with radiator fan, the silicon rubber electric heater, NTC thermistor
The wiring of type temperature sensor and radiator fan and intelligent microcomputer temperature controller substrate connection.When temperature sensor detects temperature
When degree exceeds preset upper limit value, stop heating and starting radiator fan radiating, set in advance when temperature sensor detection temperature is less than
During limit value, the heating of silicon rubber electric heater is opened.0.1 DEG C of temperature-controlled precision.
The line of the electronic digital timer and buzzer and intelligent microcomputer temperature controller substrate connection, using
The timing mode control scald time, when default scald time zero, silicon rubber electric heater is stopped, while buzzer report
It is alert, that is, terminate scald experiment.Precision 1 second during control.
The replaceable stainless steel scald first 5 is cylinder, height 5mm, and diameter specifications are respectively 6mm, 8mm, 10mm,
20mm, 30mm, 40mm, installed in the front end of heat transfer axle.
The Handheld Division and function part are perpendicular or substantially vertical mode connects, and overall is in handgun shape.
Compared with prior art, the beneficial effects of the invention are as follows：This automation degree of equipment is high, the high (temperature control of temperature-controlled precision
0~150 DEG C of scope, 0.1 DEG C of error), accurate timing (0~9999 second), compact-sized, compact, scald be replaceable, system
Cause it is low, easy to operate, easy to carry, suitable for preparing the kinds of experiments animal skins such as mouse, rat, rabbit, miniature pig
Scalding model.
Brief description of the drawings
Fig. 1 is schematic structural view of the invention.
Fig. 2 is circuit theory diagrams of the present invention.
Fig. 3 is fundamental diagram of the present invention.
Fig. 4 is the structural representation of the replaceable scald head of the present invention.
Fig. 5 is whole structure figure of the present invention.
Fig. 6 is I degree of skin scald histology figure of the present invention (normal control, scalding low power and high power figure).
Fig. 7 is light degree Ⅱ skin scald histology figure of the present invention (normal control, scalding low power and high power figure).
Fig. 8 is deep II degree of skin scald histology figure (normal control, scalding low power and high power figure) of the invention.
Fig. 9 is III degree of skin scald histology figure of the present invention (normal control, scalding low power and high power figure).
Figure 10 is IV degree of skin scald histology figure of the present invention (normal control, scalding low power and high power figure).
Embodiment
Describe embodiments of the present invention in detail with reference to the accompanying drawings and examples.
As shown in figure 1, a kind of portable digital temperature control scald apparatus, using the compact structure similar to pistol pattern,
Scald apparatus main body 1 is made up of Handheld Division and function part, and the tail end of function part is connected with Handheld Division, and Handheld Division and function part are perpendicular
Or substantially vertical mode connects, overall is in handgun shape.
Replaceable Quick Release stainless steel scald first 6 is installed by screw in the front end of function part.Reference picture 2, Fig. 3 and Fig. 4,
Quick Release stainless steel, which is scalded, to be installed NTC thermistor type temperature sensor 5 and scalds first 6 with Quick Release stainless steel on first 6 connector
It is in close contact.The stainless steel heat transfer axle for being wound with silicon rubber electric heater 4 is closely connected in the rear end of connector, after the axle that conducts heat
Side's installation radiator fan 7.Installed instruments cabin at the top of function part, and TR-WK-08 type intelligent microcomputer temperature controls are installed in cabin
Device 2, electronic digital timer 3 and alarm buzzer.Installation power switch 8 in Handheld Division and function part junction, power line
Drawn from the bottom of Handheld Division, via transformer 10, connect 220v power outlets.Silicon rubber electric heater 4, radiator fan 7, electricity
Sub- digital time-counter 3 and alarm buzzer 9 use substrate 11 corresponding binding post of the electric wire to intelligent microcomputer temperature controller 2 respectively
Connection, intelligent microcomputer temperature controller 2 carry temperature display 12.
Electronic digital timer 3 can use the clock chip of DS13 series to build, and can also use the relay form of finished product
Timer, can meet demand with the output of 1 point relay.Silicon rubber electric heater 4 mainly by nichrome heating wire and
Silicon rubber high-temperature insulating layer forms.Silicon rubber high-temperature insulating layer is the flake being combined by silicon rubber and glass fabric
(standard thickness 1.5mm), there is good flexibility.The principle of NTC thermistor type temperature sensor 5 is：Resistance value with
Temperature rises and declined rapidly, and its size is small, using flexible, can type selecting 10K-B3950.
Reference picture 4, replaceable stainless steel Quick Release scald first 6 is cylinder, and height 5mm, diameter specifications are respectively 6mm,
8mm, 10mm, 20mm, 30mm, 40mm.
The overall structure design sketch of final products is as shown in Figure 5.
Its general principle is：
Corresponding stainless steel Quick Release scald first 6 is installed according to the selection of experimental animal size, connects 220v power supplys, foundation is intended scalding
Hinder degree and required scald temperature and scald time parameter are set on intelligent microcomputer thermostat 2 and electronic timer 3, pass through
The heating heat transfer axle of silicon rubber electric heater 4 makes the first 6 temperature rise of scald, and the temperature of scald first 6 will be real-time by temperature sensor 5
Temperature data is transmitted to microcomputer controller 2, after design temperature parameter upper limit is reached, stops heating and starting radiator fan 7
Temperature of perming can be reduced.Begun to warm up when temperature is less than lower limit.When default scald time zero, buzzer warning,
Silica gel heating device 4 is stopped simultaneously, that is, terminates scald experiment.
Specific preparation method：
Scald apparatus outer casing mold is prepared, the heat-resisting engineering plastic structure main body 1 of similar pistol pattern is prepared with injection machine.
Stainless steel instrument room shell is installed in body top, (the temperature-control range of TR-WK-08 type intelligent microcomputers temperature controller 2 is installed in cabin
0~150 DEG C, 0.1 DEG C of error), electronic digital timer 3 (time range 0~9999 second) and alarm buzzer.In main body 1
Portion's middle-end installation stainless steel heat transfer axle is winding silica gel heating device 4 thereon.Lead in body front end on the connector of heat transfer axle front end
Cross screw connection and replaceable Quick Release scald first 6 is installed, the diameter of replaceable Quick Release scald first 6 is depending on selected experimental animal species
(the cylinder scald head of the supporting six kinds of diameters of the instrument：Height 5mm, diameter specifications are respectively 6mm, 8mm, 10mm, 20mm,
30mm, 40mm), Quick Release scald back of head center car has high 10mm, diameter 7mm bolt, is installed tightly to by screw thread stainless
The front end of steel heat transfer axle.Drilling insertion NTC thermistor type temperature sensor 5, makes it be close to replaceable scald on connector
First 6, it is ensured that real-time delivery scalds head temperature data.Minitype radiating fan 7 is installed at the rear that body rear is heat transfer axle.In master
The function part of body 1 and Handheld Division junction installation power switch 8, power line are drawn from the bottom of Handheld Division, connect 220v power supplys
Socket.Silicon rubber electric heater 4, radiator fan 7, electronic timer 3 and alarm buzzer use electric wire and intelligent microcomputer respectively
The corresponding binding post connection of the substrate of temperature controller 2.
Portable digital scald apparatus operating procedure：
1st, experimenter selects the replaceable scald first 6 of suitable diameter (for example, rat skin scalds according to experimental animal species
Wound model, choose diameter 20mm scald head), after head is scalded in installation, attaching plug is accessed into 220V power outlets.
2nd, experimental temperature parameter is set on TR-WK-08 type the microcomputer temperature controllers.
3rd, experimental period parameter is set on electronic digital timer.
4th, experimental animal skin surface hair is purified with hair remover, then, the Quick Release scald first 6 of preheating is adjacent to experiment
Animal unnairing area skin, presses operating switch, and scald experiment is carried out according to design temperature and time.When default scald time zero
When, buzzer warning, while silicon rubber electric heater 4 stops heating, that is, terminates scald experiment, close power supply.
5th, after completing experiment, experimental data is recorded.
In order to verify the validity and practicality of miniature portable digital temperature control scald apparatus, rat skin scald examination is carried out
Test, parameter is scalded according to scald temperature, time and the corresponding scald condition of the injury, the standardization for establishing portable digital scald apparatus.
First, experiment equipment and method：
1st, laboratory apparatus：Make miniature portable digital temperature control scald apparatus by oneself.
2nd, experimental animal：, SD rats (18,250~300g of body weight, male and female half and half), shaver, 75% ethanol, 2.5%
Yellow Jackets, 8% vulcanized sodium, 10% formaldehyde, Hematoxylin-eosin (HE), scalpel, friction clamp, tweezers, sterile gauze,
Syringe, adhesive tape, slide, cover glass, specimens paraffin embedding slices machine.
3rd, experimental method：18 SD rats, which divide cage adaptability to raise 3 days, before experiment (ensures temperature and the humidity control in laboratory
System is in optimum range), test fasted for one day prior.After rat is with 2.5% yellow Jackets (35mg/kg) intraperitoneal injection of anesthesia,
Back shaving (trying one's best, it is short to shave hair, but carefully should not injure skin), then the hair remover (8% configured in advance is dipped with gauze
Vulcanized sodium) soak wiping hair removal section, firmly rub, then with warm water cleaning, dry skin in case experiment.By 18 rats
It is divided into big group of A, B two：Respectively A groups (control group) 3, B groups (experimental group) 15.A groups (control group) rat only anaesthetizes depilation,
Tested without scald, directly cut pathological observation under normal skin tissue's row mirror；15 rat distribution of B groups (experimental group)：
1) the scald time is fixed as 20s and 30s, and scald rifle temperature is set as 70 DEG C, 80 DEG C, 90 DEG C, 100 DEG C, 120 DEG C of five temperature
Point, each time-temperature point scald 3 rats；2) scald temperature is fixed as 100 DEG C, and the scald time is set as 10s, 15s, 25s,
Each time-temperature point scalds 3 rats.The B group rats for being ready for experiment are placed in lateral position, skin of back is completely exposed,
And skin of back expansion is fixed on operation panel, diameter 20mm scald head is chosen, self-control portable digital temperature control is scalded
Hinder instrument and be adjusted to required scald temperature and time, start scald experiment.When carrying out scald experiment, scald head should be kept to be hung down with skin
Directly, it is firmly uniform, and often should stablize 5s after one temperature spot of setting and be tested again, it is ensured that temperature is constant.Rat back after wound
Region exposure is scalded without covering, continues to be put in cage and raises.Rat is anaesthetized into lethal, use with overdose of sodium pentobarbital after 48 hours
Region is scalded at 75% alcohol disinfecting back, cuts skin along the juncture area of scald and normal skin, fusiformis materials, area is about
10mm × 10mcm, cut depth and reach muscle layer.Tissue is placed in 10% formaldehyde and fixed, and is routinely dehydrated through ethanol, transparent, paraffin bag
Cut into slices, then dyed with Hematoxylin-eosin (HE), mounting Hou Hang microscopes undertissue pathological observation after burying.
2nd, experimental result：
1st, gross examination of skeletal muscle：48 hours after scald:70 DEG C of 20s groups surface of a wound are local like erythema and clear with surrounding normal skin boundary
Chu, mild redness, dry tack free；70 DEG C of 30s groups, 80 DEG C of 20s groups, 100 DEG C of 10s groups surface of a wound are around white border line, surface of a wound bottom
Portion's bright red, oedema, slightly above surface wettability, normal skin；80 DEG C of 30s groups and 100 DEG C of 15s group edema wounds are obvious, under epidermis
The thin liquid of product, surface of a wound bottom are red and white；90 DEG C of 20s groups, 90 DEG C of 30s groups, 100 DEG C of pale tarnishes of the 20s group surface of a wound, slightly below week
Enclose normal skin；100 DEG C of 25s groups, 100 DEG C of 30s groups, 120 DEG C of 20s groups, 120 DEG C of 30s group surface of a wound color and lusters are sallow, charing, dry,
The surface of a wound is hardened in leather sample.
2nd, pathological study：48 hours after scald:Visible horny layer of epidermis, hyaline layer, particle under 70 DEG C of 20s group mirrors
Layer and part acantholysis cell degeneration necrosis, histological observation meet I ° of scald；70 DEG C of 30s groups, 80 DEG C of 20s groups, 100 DEG C of 10s groups
Visible epidermis holostrome and some dermis papillaris pars degeneration necrosis, epidermis separate with corium under mirror, hair follicle deformation, fibroblast born of the same parents
Karyolysis, leukocyte infiltration occur for Irregular nucleus, and histological observation meets shallow II ° of scald；Under 80 DEG C of 30s groups and 100 DEG C of 15s group mirrors
It can be seen that epidermis and corium deep layer degeneration necrosis, hair follicle destroys, and collagenous fibres swelling and degeneration is in streak, and histological observation meets depth
II ° of scald；Visible dermis holostrome, subcutaneous layer of fat degeneration necrosis under 90 DEG C of 20s groups, 90 DEG C of 30s groups, 100 DEG C of 20s group mirrors, group
Knit observation and meet III ° of scald；Visible dermis is complete under 100 DEG C of 25s groups, 100 DEG C of 30s groups, 120 DEG C of 20s groups, 120 DEG C of 30s mirrors
The appendages of skin such as layer, subcutaneous layer of fat, muscle layer destroy completely, and histology meets IV ° of scald.
Subordinate list portable digital temperature control scald apparatus scald parameter (temperature, time and the corresponding condition of the injury)
Rat skin scalds pathology picture
Fig. 6 is I degree of skin scald histology figure of the present invention (normal control, scalding low power and high power figure).
Fig. 7 is light degree Ⅱ skin scald histology figure of the present invention (normal control, scalding low power and high power figure).
Fig. 8 is deep II degree of skin scald histology figure (normal control, scalding low power and high power figure) of the invention.
Fig. 9 is III degree of skin scald histology figure of the present invention (normal control, scalding low power and high power figure).
Figure 10 is IV degree of skin scald histology figure of the present invention (normal control, scalding low power and high power figure).
3rd, conclusion
Figure and the conclusion obtained in table are more than：This automation degree of equipment is high, temperature-controlled precision it is high (temperature-control range 0~
150 DEG C, 0.1 DEG C of error), accurate timing (0~9999 second).Scald temperature and time parameter is set according to subordinate list, can be prepared
Go out the rat I of standardization, shallow II, deep II, III, IV degree of skin scald model.Change different sizes scald heads disclosure satisfy that mouse,
The animal skins such as rat, rabbit, miniature pig scald the purpose of scientific research, in a word, the present invention be it is a kind of be applied to prepare mouse,
The portable digital scald apparatus of the Laboratory Animal Standardization skin scald model such as rat, rabbit, miniature pig.
Claims (6)
1. a kind of portable digital temperature control scald apparatus, using handheld structure, including scald apparatus main body (1), main body (1) is by hand
Portion and function part composition are held, the tail end of function part is connected with Handheld Division, it is characterised in that the front end of the function part is provided with soon
Tear stainless steel scald head (6) open, NTC temperature-sensitives electricity in close contact therewith is installed on the connector of Quick Release stainless steel scald head (6)
Resistance type temperature sensor (5), the stainless steel heat transfer axle for being wound with silicon rubber electric heater (4) is closely connected in the rear end of connector,
In the rear installation radiator fan (7) of heat transfer axle；Intelligent microcomputer temperature controller (2) is installed at the top of function part, in intelligence
Electronic digital timer (3) is installed, in Handheld Division and the junction of function part installation power supply in the microcomputer temperature controller (2) cabin
Switch (8), power line is drawn from the bottom of Handheld Division, connects 220v power outlets, silicon rubber electric heater (4), radiator fan
(7), electronic timer (3) and alarm buzzer (9) are connected with electric wire with intelligent microcomputer temperature controller (2) respectively.
2. portable digital temperature control scald apparatus according to claim 1, it is characterised in that the device of the thermostat (2)
Model TR-WK-08.
3. portable digital temperature control scald apparatus according to claim 1, it is characterised in that radiator fan (7) installation
In the position of function part face heat transfer shaft rear end, the silicon rubber electric heater (4), NTC thermistor type temperature sensor (5)
Connected with radiator fan (7) wiring to the corresponding binding post of the substrate (11) of intelligent microcomputer temperature controller (2), when NTC heat
When quick resistor-type temperature sensor (5) detection temperature exceeds preset upper limit value, stop heating and starting radiator fan (7) radiating,
When NTC thermistor type temperature sensor (5) detection temperature is less than preset lower limit value, heating, 0.1 DEG C of temperature-controlled precision are opened.
4. portable digital temperature control scald apparatus according to claim 1, it is characterised in that the electronic digital timer
(3) and the line of buzzer and intelligent microcomputer temperature controller (2) substrate connection, when controlling scald using countdown mode
Between, when default scald time zero, silicon rubber electric heater (4) is stopped, while buzzer warning, that is, it is real to terminate scald
Test, precision 1 second during control.
5. portable digital temperature control scald apparatus according to claim 1, it is characterised in that the replaceable stainless steel scald
Head (6) is cylinder, and height 5mm, diameter specifications are respectively 6mm, 8mm, 10mm, 20mm, 30mm, 40mm, by screw connection,
Installed in the front end of heat transfer axle, according to experimental animal demand, dismounting and change scald head.
6. portable digital temperature control scald apparatus according to claim 1, it is characterised in that the Handheld Division and function part are in
Vertical or substantially vertical mode connects, and overall is in handgun shape.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710943082.7A CN107736946A (en) | 2017-10-11 | 2017-10-11 | A kind of portable digital temperature control scald apparatus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710943082.7A CN107736946A (en) | 2017-10-11 | 2017-10-11 | A kind of portable digital temperature control scald apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107736946A true CN107736946A (en) | 2018-02-27 |
Family
ID=61237367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710943082.7A Pending CN107736946A (en) | 2017-10-11 | 2017-10-11 | A kind of portable digital temperature control scald apparatus |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107736946A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110354405A (en) * | 2019-07-29 | 2019-10-22 | 浙江省人民医院 | A kind of portable radiotherapy positioning thermoplastic film opener and its control method |
| CN111920542A (en) * | 2020-07-23 | 2020-11-13 | 中山大学附属第一医院 | Scald instrument and using method |
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| KR20060021590A (en) * | 2004-09-03 | 2006-03-08 | 대구 손 | Apratus for making standardized model of partial thickness burn |
| CN205234699U (en) * | 2015-12-29 | 2016-05-18 | 江林君 | Pet dog postoperative resumes auxiliary device |
| CN211512157U (en) * | 2017-10-11 | 2020-09-18 | 中国人民解放军第四军医大学 | Portable digital temperature control scald apparatus |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20060021590A (en) * | 2004-09-03 | 2006-03-08 | 대구 손 | Apratus for making standardized model of partial thickness burn |
| CN205234699U (en) * | 2015-12-29 | 2016-05-18 | 江林君 | Pet dog postoperative resumes auxiliary device |
| CN211512157U (en) * | 2017-10-11 | 2020-09-18 | 中国人民解放军第四军医大学 | Portable digital temperature control scald apparatus |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110354405A (en) * | 2019-07-29 | 2019-10-22 | 浙江省人民医院 | A kind of portable radiotherapy positioning thermoplastic film opener and its control method |
| CN111920542A (en) * | 2020-07-23 | 2020-11-13 | 中山大学附属第一医院 | Scald instrument and using method |
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