CN107723368A - One group of gene for being used for clear-cell carcinoma molecule parting and its application - Google Patents

One group of gene for being used for clear-cell carcinoma molecule parting and its application Download PDF

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CN107723368A
CN107723368A CN201711216563.4A CN201711216563A CN107723368A CN 107723368 A CN107723368 A CN 107723368A CN 201711216563 A CN201711216563 A CN 201711216563A CN 107723368 A CN107723368 A CN 107723368A
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CN107723368B (en
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徐清华
陈成书
陈金影
孙益丰
吴益旺
杨扬
蔡虎
钱琛辉
杨明
沈佳
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Hangzhou Able Gene Technology Co Ltd
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Abstract

The invention discloses one group of gene for being used for clear-cell carcinoma molecule parting and application, including following 44 genes：RHCG genes,RNF128 genes,TMEM255A genes,PCP4 genes,DHRS2 genes,CLDN8 genes,AQP6 genes,SLC18A2 genes,KRT7 genes,SERPINA5 genes,SFTPB genes,DEFB1 genes,MAL genes,ANGPTL4 genes,LCN2 genes,PLIN2 genes,ZNF395 genes,TACSTD2 genes,NDUFA4L2 genes,NNMT genes,HILPDA genes,UMOD genes,SLC12A1 genes,CALB1 genes,C7 genes,S100A2 genes,ASS1 genes,MT1G genes,ABCA8 genes,FOSB genes,MAOB genes,STAP1 genes,TFPI2 genes,AKR1C2 genes,IGFBP6 genes,VCAN genes,FLRT3 genes,MMP7 genes,GSTA1 genes,CRYAB genes,PAH genes,IGFBP1 genes,ATP6V0A4 genes,ALDOB genes.Empirical tests, the present invention can accurately distinguish oxyphilic adenoma, clear cell carcinoma, papillary cell carcinoma and chromophobe cell tumor, and its is applied widely, accuracy rate is high, and experimental period is short, and precisely treatment is carried out to patient has important clinical meaning.

Description

One group of gene for being used for clear-cell carcinoma molecule parting and its application
Technical field
The present invention relates to cancer diagnosis and biology field, and the utilization of diagnostic techniques clinically.Specifically, The present invention relates to one group of gene for being used for clear-cell carcinoma molecule parting and its application, by the foundation of clear-cell carcinoma molecule parting and The expression of the specific gene in Renal Cell Carcinoma is detected, differentiates four kinds of main tumor of kidney types, including acidophil 3 kinds of most common hypotypes of adenoma and clear-cell carcinoma：Clear cell carcinoma, papillary cell carcinoma and chromophobe cell tumor.It is in addition, of the invention Further relate to a kind of kit for clear-cell carcinoma molecule parting.
Background technology
Clear-cell carcinoma (RCC) is malignant tumour, also known as Grawitz's tumor as caused by kidney essence uriniferous tubule epithelial systems, accounts for kidney The 80%~90% of malignant tumour, account for more than the 3% of adult malignancies.Between past 20 years, China's kidney incidence of disease is with average Annual 6.5% speed rapid growth.Cancer in China statistics shows (Wanqing Chen et al., 2016), 2015 China's new case's number reaches about 6.68 ten thousand people, and male is 1.83 times of women.Death toll is estimated to exceed 2.3 ten thousand people, the death rate More than 35%, male is 1.85 times of women.
Classified according to World Health Organization in 2016, tumor of kidney shares 11 kinds of clear-cell carcinoma hypotypes, and 4 kinds of benign renals swell Knurl.Most common four type of tumor of kidney is clear cell carcinoma, papillary cell carcinoma, chromophobe cell tumor and acidophil respectively Adenoma, account for the 95% of all tumor of kidney incidences of disease.These histological subtypes are different in terms for the treatment of with prognosis, corresponding Different clinical strategies.With medicament research and development and the fast development of clinical test, future is directed to different clear-cell carcinoma hypotypes, More, more targeted selection, such as tyrosine kinase inhibitor, Sorafenib and Sutent will be had in treatment, MTOR inhibitors, everolimus and CCI-779 etc., clinician and patient is helped to realize and more accurately treat.
The clear-cell carcinoma Main Subtype of table 1 and prognosis
Type Clear cell carcinoma Papillary cell carcinoma Chromophobe cell tumor
Incidence 70% 15%~20% 6%~11%
5 years survival rates 55%~60% 80%~90% 90%
There is larger limitation in tradition, rely primarily on based on the antidiastole between morphologic kidney neoplasms different subtype In the professional standards and experience of pathologist, easily influenceed by different observers, more subjective (the Ficarra et of diagnostic result al.,2006).Even with immunohistochemistry (IHC) method, the ability for distinguishing different subtype is also challenging, spy It is not in uncommon morphology and cell check.Allory etc. describes 12 kinds of antibody intersections of a use, carries out kidney The research of dirty tumour antidiastole.Result of study shows that AMACR, CK7 and CD10 are maximally effective group indication things, but accurately Rate is also only 78-87% (Allory et al., 2008).Therefore, clinically there is an urgent need to more precisely, more considerable is new Type biomarker, discriminating and diagnosis for clear-cell carcinoma hypotype.
Tumour is genome disease.Genome change plays an important role in tumour occurrence and development.1999, the U.S. It is proposed should to be tumour point by comprehensive analysis of molecules technology in the research project recommendation that National Cancer Institute is announced first Class provides more information, so that staging turns to " molecule parting " based on characterization of molecules from traditional morphology. In recent years, as the rapid development of molecular biology and bioinformatics technique, researcher use biochip and high flux Sequencing technologies, the expression of thousands of individual genes in tumor tissues can be detected simultaneously, therefrom find related to tumor type Gene and specific expression pattern.Domestic and international correlative study report, gene expression spectrum analysis from molecular level to illustrating tumour Essence and accurate division tumor type can play important booster action.For example, Varadhachary and Talantov etc. is screened Go out 10 tissue-specific genes, differentiate lung cancer, breast cancer, colon cancer, oophoroma, cancer of pancreas and prostate cancer, this method standard True rate is 78%；Ma etc. then detects the expression of 92 genes in tumor tissues, identifies 32 kinds of tumor types, and this method is accurate Rate is 87%；Rosenfeld etc. then reports 48 microRNAs detection, identifies 22 kinds of tumor types, and accuracy rate is 89%.In China, inventor once disclosed one group of gene for being used for tumor cells parting and its applied (patent first in 2015 Application number：201510550924.3), this group of gene can be used for distinguishing 22 kinds of cancer types, and in China, masculinity and femininity is most normal See in ten big tumours, the classification accuracy of 96 genetic models respectively reaches 95.5% and 93.2%.Although this group of gene is for kidney Cell cancer and the antidiastole of other tumor types have outstanding performance, and sensitivity and specificity are 100%, but can not Distinguish each hypotype of clear-cell carcinoma.The invention provides the gene and detection reagent that one group can be used for clear-cell carcinoma molecule parting Box, to meet the clinically active demand for clear-cell carcinoma hypotype Precise Diagnosis.
The content of the invention
One of the technical problem to be solved in the present invention is to provide one group of gene for being used for clear-cell carcinoma molecule parting, establishes kidney Cell cancer Statistic analysis models, patient is helped to realize individualized treatment.
The second technical problem to be solved by the present invention is to provide the purposes of one group of gene for being used for clear-cell carcinoma molecule parting.
The third technical problem to be solved by the present invention be to provide a kind of kit for clear-cell carcinoma molecule parting and its Purposes.
The four of the technical problem to be solved in the present invention are to provide one group of gene for being used for clear-cell carcinoma molecule parting and prepared The application in genetic chip for judging clear-cell carcinoma hypotype.
In order to solve the above technical problems, the present invention adopts the following technical scheme that：
In one aspect of the invention, there is provided one group of gene for being used for clear-cell carcinoma molecule parting, including following 44 genes： RHCG genes, RNF128 genes, TMEM255A genes, PCP4 genes, DHRS2 genes, CLDN8 genes, AQP6 genes, SLC18A2 genes, KRT7 genes, SERPINA5 genes, SFTPB genes, DEFB1 genes, MAL genes, ANGPTL4 genes, LCN2 genes, PLIN2 genes, ZNF395 genes, TACSTD2 genes, NDUFA4L2 genes, NNMT genes, HILPDA genes, UMOD genes, SLC12A1 genes, CALB1 genes, C7 genes, S100A2 genes, ASS1 genes, MT1G genes, ABCA8 genes, FOSB genes, MAOB genes, STAP1 genes, TFPI2 genes, AKR1C2 genes, IGFBP6 genes, VCAN genes, FLRT3 bases Cause, MMP7 genes, GSTA1 genes, CRYAB genes, PAH genes, IGFBP1 genes, ATP6V0A4 genes, ALDOB genes.
As currently preferred technical scheme, the clear-cell carcinoma molecule parting is oxyphilic adenoma, hyaline cell Cancer, papillary cell carcinoma and chromophobe cell tumor.
As currently preferred technical scheme, the transcript sequence of 44 genes respectively is：SEQ ID NO.133-SEQ ID NO.176。
The present invention establishes gene marker by the use in conjunction of genetic test, mark combination and data mining algorithm Built-up pattern, most common four type of tumor of kidney is distinguished using polygenes forecast model, i.e. clear cell carcinoma is (most common Hypotype), papillary cell carcinoma, chromophobe cell tumor and oxyphilic adenoma.Mainly include the following steps that：
(1) the clinical diagnosis data and gene expression data base of tumor of kidney are collected, structure is comprising 12263 known to the mankind The clear-cell carcinoma gene expression profile data storehouse of gene, 295 samples；
(2) statistical analysis is carried out to gene expression pattern, filters out 44 genes closely related with tumor of kidney hypotype, Respectively RHCG genes, RNF128 genes, TMEM255A genes, PCP4 genes, DHRS2 genes, CLDN8 genes, AQP6 genes, SLC18A2 genes, KRT7 genes, SERPINA5 genes, SFTPB genes, DEFB1 genes, MAL genes, ANGPTL4 genes, LCN2 genes, PLIN2 genes, ZNF395 genes, TACSTD2 genes, NDUFA4L2 genes, NNMT genes, HILPDA genes, UMOD genes, SLC12A1 genes, CALB1 genes, C7 genes, S100A2 genes, ASS1 genes, MT1G genes, ABCA8 genes, FOSB genes, MAOB genes, STAP1 genes, TFPI2 genes, AKR1C2 genes, IGFBP6 genes, VCAN genes, FLRT3 bases Cause, MMP7 genes, GSTA1 genes, CRYAB genes, PAH genes, IGFBP1 genes, ATP6V0A4 genes, ALDOB genes.
(3) above-mentioned 44 gene expression patterns are calculated, clear-cell carcinoma hypotype is evaluated by Statistic analysis models, are counted Calculate biological sample and the similarity score (Similarity Score) of clear-cell carcinoma hypotype.According to similarity score highest Decision rule, type belonging to judgement.
The invention provides a kind of detection method for being used to judge clear-cell carcinoma type, comprise the following steps：
(1) biological sample for being derived from kidney neoplasms patient is contacted with biomarker, the biomarker includes upper State 44 genes；The biological sample is taken from the tumor tissue in vitro of the object, can be fresh sample or good fortune FFPE (FFPE) sample that your Malin fixes.
On this basis, clear-cell carcinoma hypotype judgement is further carried out：
(2) expression pattern and expression of 44 genes in the biological sample, the expression based on 44 genes are detected Level judges the type of the biological sample.Using data analysing method, the biological sample and clear-cell carcinoma hypotype are calculated Similarity score (Similarity Score).According to similarity score highest decision rule, determined type.The detection Including being used for PCR (PCR) from the sample preparation RNA, the RNA, the PCR is reverse transcription PCR (RT- PCR), optional real-time RT-PCR either genetic chip or high throughput sequencing technologies.
In another aspect of this invention, there is provided one group of gene for being used for clear-cell carcinoma molecule parting is used for nephrocyte in preparation Application in the kit of cancer molecule parting.
In another aspect of this invention, there is provided a kind of kit for clear-cell carcinoma molecule parting, the kit include Following biomarker, the biomarker are used for any one in the gene of clear-cell carcinoma molecule parting selected from above-mentioned one group Kind is a variety of.
As currently preferred technical scheme, the biomarker is nucleic acid, oligonucleotide chain or PCR primer group.
As currently preferred technical scheme, the PCR primer group includes：
RHCG genes：Forward primer is as shown in SEQ ID NO.1, and reverse primer is as shown in SEQ ID NO.2；
RNF128 genes：Forward primer is as shown in SEQ ID NO.3, and reverse primer is as shown in SEQ ID NO.4；
TMEM255A genes：Forward primer is as shown in SEQ ID NO.5, and reverse primer is as shown in SEQ ID NO.6；
PCP4 genes：Forward primer is as shown in SEQ ID NO.7, and reverse primer is as shown in SEQ ID NO.8；
DHRS2 genes：Forward primer is as shown in SEQ ID NO.9, and reverse primer is as shown in SEQ ID NO.10；
CLDN8 genes：Forward primer is as shown in SEQ ID NO.11, and reverse primer is as shown in SEQ ID NO.12；
AQP6 genes：Forward primer is as shown in SEQ ID NO.13, and reverse primer is as shown in SEQ ID NO.14；
SLC18A2 genes：Forward primer is as shown in SEQ ID NO.15, and reverse primer is as shown in SEQ ID NO.16；
KRT7 genes：Forward primer is as shown in SEQ ID NO.17, and reverse primer is as shown in SEQ ID NO.18；
SERPINA5 genes：Forward primer is as shown in SEQ ID NO.19, and reverse primer is as shown in SEQ ID NO.20；
SFTPB genes：Forward primer is as shown in SEQ ID NO.21, and reverse primer is as shown in SEQ ID NO.22；
DEFB1 genes：Forward primer is as shown in SEQ ID NO.23, and reverse primer is as shown in SEQ ID NO.24；
MAL genes：Forward primer is as shown in SEQ ID NO.25, and reverse primer is as shown in SEQ ID NO.26；
ANGPTL4 genes：Forward primer is as shown in SEQ ID NO.27, and reverse primer is as shown in SEQ ID NO.28；
LCN2 genes：Forward primer is as shown in SEQ ID NO.29, and reverse primer is as shown in SEQ ID NO.30；
PLIN2 genes：Forward primer is as shown in SEQ ID NO.31, and reverse primer is as shown in SEQ ID NO.32；
ZNF395 genes：Forward primer is as shown in SEQ ID NO.33, and reverse primer is as shown in SEQ ID NO.34；
TACSTD2 genes：Forward primer is as shown in SEQ ID NO.35, and reverse primer is as shown in SEQ ID NO.36；
NDUFA4L2 genes：Forward primer is as shown in SEQ ID NO.37, and reverse primer is as shown in SEQ ID NO.38；
NNMT genes：Forward primer is as shown in SEQ ID NO.39, and reverse primer is as shown in SEQ ID NO.40；
HILPDA genes：Forward primer is as shown in SEQ ID NO.41, and reverse primer is as shown in SEQ ID NO.42；
UMOD genes：Forward primer is as shown in SEQ ID NO.43, and reverse primer is as shown in SEQ ID NO.44；
SLC12A1 genes：Forward primer is as shown in SEQ ID NO.45, and reverse primer is as shown in SEQ ID NO.46；
CALB1 genes：Forward primer is as shown in SEQ ID NO.47, and reverse primer is as shown in SEQ ID NO.48；
C7 genes：Forward primer is as shown in SEQ ID NO.49, and reverse primer is as shown in SEQ ID NO.50；
S100A2 genes：Forward primer is as shown in SEQ ID NO.51, and reverse primer is as shown in SEQ ID NO.52；
ASS1 genes：Forward primer is as shown in SEQ ID NO.53, and reverse primer is as shown in SEQ ID NO.54；
MT1G genes：Forward primer is as shown in SEQ ID NO.55, and reverse primer is as shown in SEQ ID NO.56；
ABCA8 genes：Forward primer is as shown in SEQ ID NO.57, and reverse primer is as shown in SEQ ID NO.58；
FOSB genes：Forward primer is as shown in SEQ ID NO.59, and reverse primer is as shown in SEQ ID NO.60；
MAOB genes：Forward primer is as shown in SEQ ID NO.61, and reverse primer is as shown in SEQ ID NO.62；
STAP1 genes：Forward primer is as shown in SEQ ID NO.63, and reverse primer is as shown in SEQ ID NO.64；
TFPI2 genes：Forward primer is as shown in SEQ ID NO.65, and reverse primer is as shown in SEQ ID NO.66；
AKR1C2 genes：Forward primer is as shown in SEQ ID NO.67, and reverse primer is as shown in SEQ ID NO.68；
IGFBP6 genes：Forward primer is as shown in SEQ ID NO.69, and reverse primer is as shown in SEQ ID NO.70；
VCAN genes：Forward primer is as shown in SEQ ID NO.71, and reverse primer is as shown in SEQ ID NO.72；
FLRT3 genes：Forward primer is as shown in SEQ ID NO.73, and reverse primer is as shown in SEQ ID NO.74；
MMP7 genes：Forward primer is as shown in SEQ ID NO.75, and reverse primer is as shown in SEQ ID NO.76；
GSTA1 genes：Forward primer is as shown in SEQ ID NO.77, and reverse primer is as shown in SEQ ID NO.78；
CRYAB genes：Forward primer is as shown in SEQ ID NO.79, and reverse primer is as shown in SEQ ID NO.80；
PAH genes：Forward primer is as shown in SEQ ID NO.81, and reverse primer is as shown in SEQ ID NO.82；
IGFBP1 genes：Forward primer is as shown in SEQ ID NO.83, and reverse primer is as shown in SEQ ID NO.84；
ATP6V0A4 genes：Forward primer is as shown in SEQ ID NO.85, and reverse primer is as shown in SEQ ID NO.86；
ALDOB genes：Forward primer is as shown in SEQ ID NO.87, and reverse primer is as shown in SEQ ID NO.88.
The application method of mentioned reagent box comprises the following steps：
(1) biological sample comprising tumor tissues is contacted with biomarker；
(2) expression of the mark in the biological sample is determined；
(3) expression pattern of gene in biological sample is detected, and itself and clear-cell carcinoma gene expression profile data storehouse are entered Row compares.
The expression of kit detection can by real-time quantitative reverse transcriptase polymerase chain reaction (RT-PCR), or Genetic chip, or high throughput sequencing technologies.
The expression of described kit detection is mRNA expressions.
Example only as the above-mentioned subsidy of the present invention, for FFPE kidney neoplasms tissue, utilizes real-time quantitative reverse transcription PCR (RT-PCR), the method for distinguishing clear-cell carcinoma hypotype, is comprised the steps of：
(1) paraffin-embedded tissue of kidney neoplasms tissue is obtained；
(2) expression of 44 genes in the sample is detected with real-time quantitative reverse transcriptase polymerase chain reaction；
(3) expression pattern of 44 genes in the sample is detected, and itself and clear-cell carcinoma gene expression profile data are carried out Compare, distinguish clear-cell carcinoma hypotype.
In another aspect of the present invention, there is provided described kit is preparing the use in judging the preparation of clear-cell carcinoma type On the way.
In another aspect of the present invention, there is provided one group of gene for being used for clear-cell carcinoma molecule parting is being prepared for judging that kidney is thin Application in the genetic chip of born of the same parents' cancer type, the genetic chip include solid phase carrier and probe, the probe with 44 to be measured Gene order and/or its complementary series are hybridized, and 44 genes to be measured are：RHCG genes, RNF128 genes, TMEM255A bases Cause, PCP4 genes, DHRS2 genes, CLDN8 genes, AQP6 genes, SLC18A2 genes, KRT7 genes, SERPINA5 genes, SFTPB genes, DEFB1 genes, MAL genes, ANGPTL4 genes, LCN2 genes, PLIN2 genes, ZNF395 genes, TACSTD2 Gene, NDUFA4L2 genes, NNMT genes, HILPDA genes, UMOD genes, SLC12A1 genes, CALB1 genes, C7 genes, S100A2 genes, ASS1 genes, MT1G genes, ABCA8 genes, FOSB genes, MAOB genes, STAP1 genes, TFPI2 genes, AKR1C2 genes, IGFBP6 genes, VCAN genes, FLRT3 genes, MMP7 genes, GSTA1 genes, CRYAB genes, PAH bases Cause, IGFBP1 genes, ATP6V0A4 genes, ALDOB genes.The probe is SEQ ID NO.89~SEQ ID respectively Sequence shown in NO.132.
Present invention structure Statistic analysis models, by detecting 44 genes related to tumor of kidney, distinguish clear-cell carcinoma Hypotype, i.e. oxyphilic adenoma and 3 kinds of most common hypotypes：Clear cell carcinoma, papillary cell carcinoma and chromophobe cell tumor.Help is cured It is raw to carry out medication guide, precisely medical treatment is realized, to improve the survival rate of renal cell carcinoma patients.Empirical tests, kit energy of the present invention Oxyphilic adenoma, clear cell carcinoma, papillary cell carcinoma and chromophobe cell tumor are accurately distinguished, its applied widely, accuracy rate Height, experimental period is short, and precisely treatment is carried out to patient has important clinical meaning.
Brief description of the drawings
Fig. 1 is the differentiation result schematic diagram of 44 gene Diagnosis of Renal Cell Carcinoma in the embodiment of the present invention 3.
Embodiment
Following examples are merely to illustrate book invention, rather than limitation the scope of the present invention.Unreceipted tool in embodiment The experimental method of concrete conditions in the establishment of a specific crime, according to the condition proposed by manufacture kit production company or according to conventional laboratory conditions, such as Sambrook et al., molecular cloning：Laboratory manual (New York:Cold Spring Harbor Laboratory Press, 1989) condition described in.Unless otherwise defined, all specialties used in text are ripe with this area with scientific words It is identical to practice meaning known to personnel.In addition, any method similar or impartial to described content and material all can be applied to In the present invention.Preferable implementation described in text and material only present a demonstration effect.
Embodiment 1.
Training set sample Collecting and dealing；
The present invention analyzes substantial amounts of kidney neoplasms patient clinical data and its biological sample data, including 106 Clear cell carcinoma, 66 papillary cell carcinomas, 42 chromophobe cell tumors, 46 oxyphilic adenomas, 35 nonneoplastic tissues amount to The relevant clinical data and gene expression data of 295 patients, build clear-cell carcinoma gene expression data base.
The screening of 44 specific genes；
According to the measured value of gene expression abundance, inventor is examined using statistical analysis technique T and brushed from 12263 genes Select 44 genes closely related with clear-cell carcinoma parting.These genes having differences property in clear-cell carcinoma hypotype is expressed, With statistical significance, 1 is shown in Table.
Table 2：44 gene sets
Structure of 44 genes based on Statistic analysis models：
Expression pattern based on 44 specific genes in 295 kidney neoplasms samples, inventor use SVMs (Support Vector Machines) algorithm, establish Statistic analysis models and be used to differentiate tumor of kidney type.For each example Sample to be tested, model calculate the sample gene expression pattern and clear cell carcinoma, papillary cell carcinoma, chromophobe in database Cancer and the similarity score of oxyphilic adenoma, and differentiate according to similarity score maximum principle the tumor type of the sample.From Since invention in 1992, algorithm of support vector machine has been widely used in and has solved the problems, such as all kinds of identifications, including finance data point Analysis, speech recognition and biological data analysis.Those skilled in the art can by free analysis software of increasing income, such as：R、 Rapidminer and WEKA uses algorithm of support vector machine.Algorithm of support vector machine is not limited solely to, other data informed Method for digging can all use, such as the closest value (K-nearest of Nearest Neighbor with Weighted Voting (Weighted Voting), K- Neighbors), random forest (Random Forest), relative coefficient (Correlation Coefficients) etc..
Embodiment 2.
Checking collection test：
In the present embodiment, inventor analyzes the high-flux sequence data for including 1020 clear-cell carcinomas, wherein having transparent 534,291 papillary cell carcinomas of cell cancer, 66 chromophobe cell tumors and 129 nonneoplastic tissues.Counted by 44 genes Analysis model to each sample carry out type differentiation, and with Clinicopathologic Diagnosis results contrast, accuracy rate 93.4%,.With Clear cell carcinoma is reference, and the susceptibility of prediction is 94.2%, and specificity is 95.7%, is shown in Table 2.
Table 3：The differentiation result that 44 genetic models are concentrated in 1020 checkings
Embodiment 3.
In the present embodiment, it is real that inventor carries out molecule parting to 121 kidney neoplasms samples and 8 nonneoplastic tissue samples Test, wherein clear cell carcinoma 26, papillary cell carcinoma 28, chromophobe cell tumor 40 and oxyphilic adenoma 27.Experiment Personnel by hand from formalin fix kidney neoplasms enrichment region collected on the tissue block of FFPE by the mode of scraping blade, and extracts total RNA；Handled with DNase to ensure to remove the pollution of genomic DNA completely；CDNA is obtained after reverse transcription, carries out 44 genes Realtime quantitative inspection (real-time quantitative polymerase chain reaction, RTQ- PCR the expression of gene in FFPE tumor tissues) is detected, analysis model calculates the sample and the phase of clear-cell carcinoma hypotype Like degree fraction.
By differentiation of the 44 gene Statistic analysis models to each sample type, and compared with clinical case diagnostic result Compared with accuracy rate 93.0%.Using clear cell carcinoma of kidney as reference, the susceptibility of prediction is 96.2%, specificity 96.1%, is seen Table 3.
Table 4：The differentiation result that 44 genetic models are concentrated in 129 checkings
The PCR primer group difference of 44 genes of design is as follows：
RHCG genes：Forward primer is as shown in SEQ ID NO.1, and reverse primer is as shown in SEQ ID NO.2；
RNF128 genes：Forward primer is as shown in SEQ ID NO.3, and reverse primer is as shown in SEQ ID NO.4；
TMEM255A genes：Forward primer is as shown in SEQ ID NO.5, and reverse primer is as shown in SEQ ID NO.6；
PCP4 genes：Forward primer is as shown in SEQ ID NO.7, and reverse primer is as shown in SEQ ID NO.8；
DHRS2 genes：Forward primer is as shown in SEQ ID NO.9, and reverse primer is as shown in SEQ ID NO.10；
CLDN8 genes：Forward primer is as shown in SEQ ID NO.11, and reverse primer is as shown in SEQ ID NO.12；
AQP6 genes：Forward primer is as shown in SEQ ID NO.13, and reverse primer is as shown in SEQ ID NO.14；
SLC18A2 genes：Forward primer is as shown in SEQ ID NO.15, and reverse primer is as shown in SEQ ID NO.16；
KRT7 genes：Forward primer is as shown in SEQ ID NO.17, and reverse primer is as shown in SEQ ID NO.18；
SERPINA5 genes：Forward primer is as shown in SEQ ID NO.19, and reverse primer is as shown in SEQ ID NO.20；
SFTPB genes：Forward primer is as shown in SEQ ID NO.21, and reverse primer is as shown in SEQ ID NO.22；
DEFB1 genes：Forward primer is as shown in SEQ ID NO.23, and reverse primer is as shown in SEQ ID NO.24；
MAL genes：Forward primer is as shown in SEQ ID NO.25, and reverse primer is as shown in SEQ ID NO.26；
ANGPTL4 genes：Forward primer is as shown in SEQ ID NO.27, and reverse primer is as shown in SEQ ID NO.28；
LCN2 genes：Forward primer is as shown in SEQ ID NO.29, and reverse primer is as shown in SEQ ID NO.30；
PLIN2 genes：Forward primer is as shown in SEQ ID NO.31, and reverse primer is as shown in SEQ ID NO.32；
ZNF395 genes：Forward primer is as shown in SEQ ID NO.33, and reverse primer is as shown in SEQ ID NO.34；
TACSTD2 genes：Forward primer is as shown in SEQ ID NO.35, and reverse primer is as shown in SEQ ID NO.36；
NDUFA4L2 genes：Forward primer is as shown in SEQ ID NO.37, and reverse primer is as shown in SEQ ID NO.38；
NNMT genes：Forward primer is as shown in SEQ ID NO.39, and reverse primer is as shown in SEQ ID NO.40；
HILPDA genes：Forward primer is as shown in SEQ ID NO.41, and reverse primer is as shown in SEQ ID NO.42；
UMOD genes：Forward primer is as shown in SEQ ID NO.43, and reverse primer is as shown in SEQ ID NO.44；
SLC12A1 genes：Forward primer is as shown in SEQ ID NO.45, and reverse primer is as shown in SEQ ID NO.46；
CALB1 genes：Forward primer is as shown in SEQ ID NO.47, and reverse primer is as shown in SEQ ID NO.48；
C7 genes：Forward primer is as shown in SEQ ID NO.49, and reverse primer is as shown in SEQ ID NO.50；
S100A2 genes：Forward primer is as shown in SEQ ID NO.51, and reverse primer is as shown in SEQ ID NO.52；
ASS1 genes：Forward primer is as shown in SEQ ID NO.53, and reverse primer is as shown in SEQ ID NO.54；
MT1G genes：Forward primer is as shown in SEQ ID NO.55, and reverse primer is as shown in SEQ ID NO.56；
ABCA8 genes：Forward primer is as shown in SEQ ID NO.57, and reverse primer is as shown in SEQ ID NO.58；
FOSB genes：Forward primer is as shown in SEQ ID NO.59, and reverse primer is as shown in SEQ ID NO.60；
MAOB genes：Forward primer is as shown in SEQ ID NO.61, and reverse primer is as shown in SEQ ID NO.62；
STAP1 genes：Forward primer is as shown in SEQ ID NO.63, and reverse primer is as shown in SEQ ID NO.64；
TFPI2 genes：Forward primer is as shown in SEQ ID NO.65, and reverse primer is as shown in SEQ ID NO.66；
AKR1C2 genes：Forward primer is as shown in SEQ ID NO.67, and reverse primer is as shown in SEQ ID NO.68；
IGFBP6 genes：Forward primer is as shown in SEQ ID NO.69, and reverse primer is as shown in SEQ ID NO.70；
VCAN genes：Forward primer is as shown in SEQ ID NO.71, and reverse primer is as shown in SEQ ID NO.72；
FLRT3 genes：Forward primer is as shown in SEQ ID NO.73, and reverse primer is as shown in SEQ ID NO.74；
MMP7 genes：Forward primer is as shown in SEQ ID NO.75, and reverse primer is as shown in SEQ ID NO.76；
GSTA1 genes：Forward primer is as shown in SEQ ID NO.77, and reverse primer is as shown in SEQ ID NO.78；
CRYAB genes：Forward primer is as shown in SEQ ID NO.79, and reverse primer is as shown in SEQ ID NO.80；
PAH genes：Forward primer is as shown in SEQ ID NO.81, and reverse primer is as shown in SEQ ID NO.82；
IGFBP1 genes：Forward primer is as shown in SEQ ID NO.83, and reverse primer is as shown in SEQ ID NO.84；
ATP6V0A4 genes：Forward primer is as shown in SEQ ID NO.85, and reverse primer is as shown in SEQ ID NO.86；
ALDOB genes：Forward primer is as shown in SEQ ID NO.87, and reverse primer is as shown in SEQ ID NO.88.
The probe sequence difference of 44 genes is as shown in table 5 below：
Table 5
The transcript sequence difference of 44 genes is as shown in table 6 below：
Table 6
As a result as shown in figure 1, papillary cell carcinoma, clear cell carcinoma, chromophobe cell tumor, oxyphilic adenoma, non-tumour The similarity score of tissue is respectively 94.3,4.5,0.6,0.4,0.3.Due to papillary cell carcinoma highest, therefore the sample quilt It is determined as papillary cell carcinoma, is consistent with Clinicopathologic Diagnosis result.
Embodiment described above only expresses embodiments of the present invention, and its description is more specific and detailed, but can not Therefore it is interpreted as the limitation to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, Without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the protection model of the present invention Enclose.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
Sequence table
<110>Hangzhou can help Gene Tech. Company Limited
<120>One group of gene for being used for clear-cell carcinoma molecule parting and its application
<130> HJ17-14297
<160> 176
<170> PatentIn version 3.5
<210> 1
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 1
cccattcagc tgctcatcat 20
<210> 2
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 2
ctcctgcatc cttcaccttt ag 22
<210> 3
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 3
cctggattgc gctgatagaa 20
<210> 4
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 4
ccagtctctg gagcattgta aa 22
<210> 5
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 5
ctggtggctt ctatcgtgtt ta 22
<210> 6
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 6
ggttagcgta gagtggtttc ag 22
<210> 7
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 7
ggactgagct gttgagttag ag 22
<210> 8
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 8
gtgcatccat gtcaatgtca aa 22
<210> 9
<211> 21
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 9
tcacaagcag gatcagcata g 21
<210> 10
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 10
agacttggct ctgagctttc 20
<210> 11
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 11
gcttccgtga tgtccttctt 20
<210> 12
<211> 21
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 12
gagccttcac cttctcattg t 21
<210> 13
<211> 23
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 13
gcctctccca ataggtcttt att 23
<210> 14
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 14
ttcctctatc ccacctctct ac 22
<210> 15
<211> 21
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 15
actgtcccag tgaagacaaa g 21
<210> 16
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 16
tcctatgaaa gggttggtga tg 22
<210> 17
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 17
accacccaca atcacaagaa 20
<210> 18
<211> 23
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 18
ggctgcttta ttggaagcta ttc 23
<210> 19
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 19
cagctacggg acacatttca 20
<210> 20
<211> 23
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 20
ccagagttag tgtggagcat aag 23
<210> 21
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 21
gcctatccca aacctacaag aa 22
<210> 22
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 22
ccctgtgaag agactaccaa ac 22
<210> 23
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 23
gtggagggca atgtctctat tc 22
<210> 24
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 24
tcacttctgc gtcatttctt ct 22
<210> 25
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 25
cgtgacctga gaaggaaaga aa 22
<210> 26
<211> 21
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 26
gggagagctt gtggacaata c 21
<210> 27
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 27
gaggctggac agtaattcag ag 22
<210> 28
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 28
cgtgatgcta tgcaccttct 20
<210> 29
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 29
ggagctgact tcggaactaa ag 22
<210> 30
<211> 21
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 30
cgtcgataca ctggtcgatt g 21
<210> 31
<211> 23
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 31
gattgaggag agactgccta ttc 23
<210> 32
<211> 21
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 32
cagtagtcgt cacagcatct t 21
<210> 33
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 33
ccagtttgga ccgtgtagat ataa 24
<210> 34
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 34
cacactgctc tctcccttta tt 22
<210> 35
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 35
cagggtctcc tttctttctc ac 22
<210> 36
<211> 21
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 36
ctatgccatc ccttccttca c 21
<210> 37
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 37
ctgctgggac agaaagaaca 20
<210> 38
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 38
cggtccttct tcagcttctt at 22
<210> 39
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 39
acctccaagg acacctatct 20
<210> 40
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 40
cacaccgtct aggcagaata tc 22
<210> 41
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 41
gccttgaaga acctgtctaa ct 22
<210> 42
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 42
cctcccaaag tgctaggatt ac 22
<210> 43
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 43
ctatccaagt ggtggagaat gg 22
<210> 44
<211> 21
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 44
gacttcacag tgcaggtaga c 21
<210> 45
<211> 21
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 45
aagctccctt gacagagatt g 21
<210> 46
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 46
cacctgaaga acctgagaga tg 22
<210> 47
<211> 21
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 47
ctcatcacag cctcacagtt t 21
<210> 48
<211> 21
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 48
actccaatcc agccttcttt c 21
<210> 49
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 49
gggttcttcg tattcaggta gg 22
<210> 50
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 50
cctggctagt tgctaggtaa tc 22
<210> 51
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 51
atgagtggga atggcaagag 20
<210> 52
<211> 23
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 52
ctcccagggt gaggatttat atg 23
<210> 53
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 53
cccgcaaaca agtggaaatc 20
<210> 54
<211> 21
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 54
ccagggagca atgaccttta t 21
<210> 55
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 55
tcgcttggga actctagtct 20
<210> 56
<211> 19
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 56
tcttgcagga ggtgcattt 19
<210> 57
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 57
gaaggccaaa tcactgcaat ac 22
<210> 58
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 58
ggaacagaca acccactaag aa 22
<210> 59
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 59
cctcgctctg tgaactcttt ag 22
<210> 60
<211> 21
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 60
acacacccac tttgtctctt c 21
<210> 61
<211> 21
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 61
gtcaagtgag tgagcggata a 21
<210> 62
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 62
gggtctccac aaggacattt 20
<210> 63
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 63
cggaaagagg caactgagat 20
<210> 64
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 64
ctgccgaata gtgatggagt ag 22
<210> 65
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 65
ctgccaatgt gactcgctat ta 22
<210> 66
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 66
caatcctccc tgctaacaaa gt 22
<210> 67
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 67
tgccagctca ttgctcttat ag 22
<210> 68
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 68
tcagcttcac acactggtat tt 22
<210> 69
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 69
tggagctgtc atcactcaac 20
<210> 70
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 70
gccaacacca acactctttc 20
<210> 71
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 71
ggcacctgtt atcctactga aa 22
<210> 72
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 72
gctccattac gacagggatt ag 22
<210> 73
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 73
cattgccctt cttgctttag tg 22
<210> 74
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 74
atcctttctt ctcctccctt tg 22
<210> 75
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 75
gttaaactcc cgcgtcatag aa 22
<210> 76
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 76
gatcctgtag gtgaccactt tg 22
<210> 77
<211> 23
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 77
taaagagcca tggacaagac tac 23
<210> 78
<211> 21
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 78
agagggaagc tggagataag a 21
<210> 79
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 79
ctacttccct gagtcccttc ta 22
<210> 80
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 80
agagaacctg tccttctcca 20
<210> 81
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 81
ctgctttcct ctcgggattt 20
<210> 82
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 82
ctcatggcag atgtcaggtt 20
<210> 83
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 83
ctctccatgt caccaacatc aa 22
<210> 84
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 84
gtgccttggc taaactctct ac 22
<210> 85
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 85
cagccatacc aggagtgtat tt 22
<210> 86
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 86
aggatcaccg acatcttcat tt 22
<210> 87
<211> 20
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 87
tactgttcct gcagctgttc 20
<210> 88
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<220>
<221> misc_feature
<223>Primer
<400> 88
ggtagagggc aaaggttgat ag 22
<210> 89
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 89
ttccaagtga ccctcttcgc tgtg 24
<210> 90
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 90
caaacagcgg gcagaagaaa tgct 24
<210> 91
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 91
cagctttggt gtgattgcgg cttt 24
<210> 92
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 92
aacatgagtg agcgacaagg tgct 24
<210> 93
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 93
acatctagct cccagcatgg caat 24
<210> 94
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 94
ccatccttgg catgaaatgc acca 24
<210> 95
<211> 25
<212> DNA
<213>Artificial sequence (unknown)
<400> 95
cccacccttg agaagaactg acaca 25
<210> 96
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 96
ctgttgtttg cctcgaaagc cacc 24
<210> 97
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 97
catgcctggt cccaagacag tgag 24
<210> 98
<211> 23
<212> DNA
<213>Artificial sequence (unknown)
<400> 98
atccaaggca gcagaggtga gtg 23
<210> 99
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 99
taatcccacc accctttgct gact 24
<210> 100
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 100
agcacttggc cttccctctg taac 24
<210> 101
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 101
tggagcagct ctcgagaact acct 24
<210> 102
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 102
acgatggctc agtggacttc aacc 24
<210> 103
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 103
atccgcttct ccaaatctct gggc 24
<210> 104
<211> 23
<212> DNA
<213>Artificial sequence (unknown)
<400> 104
caatgccaaa ggcgctgtga ctg 23
<210> 105
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 105
tgcaggcttc ttatgccgtt ggta 24
<210> 106
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 106
tcggtccaac aacaggaaac ctga 24
<210> 107
<211> 27
<212> DNA
<213>Artificial sequence (unknown)
<400> 107
acaagttcct tgcagtttcc actgact 27
<210> 108
<211> 26
<212> DNA
<213>Artificial sequence (unknown)
<400> 108
acaagtttgg ttctaggcac tctgca 26
<210> 109
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<400> 109
caaggcctgt ttaggccggt tg 22
<210> 110
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 110
tccagatgtt ccggtttgct ggaa 24
<210> 111
<211> 26
<212> DNA
<213>Artificial sequence (unknown)
<400> 111
tggctgattc tgactataac cacgcc 26
<210> 112
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 112
tcagcgtcga aatggagcca gatc 24
<210> 113
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 113
tggagtgcca agcaggaaat ctga 24
<210> 114
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 114
aggttgaggc aggtttggtt tcct 24
<210> 115
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 115
agctcaaacc ggacctgatc gttc 24
<210> 116
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 116
cagctcctgc aagtgcaaag agtg 24
<210> 117
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 117
tggagctgga aagtcaacac tgct 24
<210> 118
<211> 25
<212> DNA
<213>Artificial sequence (unknown)
<400> 118
aggaggagga gaaggaggag agaga 25
<210> 119
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 119
ttggagaccg agtgaagctg gaga 24
<210> 120
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 120
tgatcctgag gcctggtagt gaca 24
<210> 121
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 121
actggctgtg gagggaatga caat 24
<210> 122
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 122
aaccaggcca gtgacagaaa tgga 24
<210> 123
<211> 22
<212> DNA
<213>Artificial sequence (unknown)
<400> 123
aggccctcaa tccaccttca gg 22
<210> 124
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 124
acagcggaga ccagtgtgaa cttg 24
<210> 125
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 125
tcgctcttct caaggaactg tgca 24
<210> 126
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 126
aatgcagaag cccagatgtg gagt 24
<210> 127
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 127
cgggctgaca ttcatctggt ggaa 24
<210> 128
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 128
agctggtttg acactggact ctca 24
<210> 129
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 129
ttccgagtct tccactgcac acag 24
<210> 130
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 130
aaatggaagg agccctgccg aata 24
<210> 131
<211> 25
<212> DNA
<213>Artificial sequence (unknown)
<400> 131
ccatacccgt ttgggattga tccga 25
<210> 132
<211> 24
<212> DNA
<213>Artificial sequence (unknown)
<400> 132
tggtggcatg agtgaagagg atgc 24
<210> 133
<211> 1952
<212> DNA
<213>Artificial sequence (unknown)
<400> 133
gaaccgcccg ctgccagccc ggccaggcac ccctgcagca tggcctggaa caccaacctc 60
cgctggcggc tgccgctcac ctgcctgctc ctgcaggtga ttatggtgat tctcttcggg 120
gtgttcgtgc gctacgactt cgaggccgac gcccactggt ggtcagagag gacgcacaag 180
aacttgagcg acatggagaa cgaattctac tatcgctacc caagcttcca ggacgtgcac 240
gtgatggtct tcgtgggctt cggcttcctc atgactttcc tgcagcgcta cggcttcagc 300
gccgtgggct tcaacttcct gttggcagcc ttcggcatcc agtgggcgct gctcatgcag 360
ggctggttcc acttcttaca agaccgctac atcgtcgtgg gcgtggagaa cctcatcaac 420
gctgacttct gcgtggcctc tgtctgcgtg gcctttgggg cagttctggg taaagtcagc 480
cccattcagc tgctcatcat gactttcttc caagtgaccc tcttcgctgt gaatgagttc 540
attctcctta acctgctaaa ggtgaaggat gcaggaggct ccatgaccat ccacacattt 600
ggcgcctact ttgggctcac agtgacccgg atcctctacc gacgcaacct agagcagagc 660
aaggagagac agaattctgt gtaccagtcg gacctctttg ccatgattgg caccctcttc 720
ctgtggatgt actggcccag cttcaactca gccatatcct accatgggga cagccagcac 780
cgagccgcca tcaacaccta ctgctccttg gcagcctgcg tgcttacctc ggtggcaata 840
tccagtgccc tgcacaagaa gggcaagctg gacatggtgc acatccagaa tgccacgctc 900
gcaggagggg tggccgtggg taccgctgct gagatgatgc tcatgcctta cggtgccctc 960
atcatcggct tcgtctgcgg catcatctcc accctgggtt ttgtatacct gaccccattc 1020
ctggagtccc ggctgcacat ccaggacaca tgtggcatta acaatctgca tggcattcct 1080
ggcatcatag gcggcatcgt gggtgctgtg acagcggcct ccgccagcct tgaagtctat 1140
ggaaaagaag ggcttgtcca ttcctttgac tttcaaggtt tcaacgggga ctggaccgca 1200
agaacacagg gaaagttcca gatttatggt ctcttggtga ccctggccat ggccctgatg 1260
ggtggcatca ttgtggggct cattttgaga ttaccattct ggggacaacc ttcagatgag 1320
aactgctttg aggatgcggt ctactgggag atgcctgaag ggaacagcac tgtctacatc 1380
cctgaggacc ccaccttcaa gccctcagga ccctcagtac cctcagtacc catggtgtcc 1440
ccactaccca tggcttcctc ggtacccttg gtaccctagg ctcccagggc aggctccaca 1500
gactgtcctg gggcccagag gagctggtgc tgacctagct agggatgcaa gagtgagcaa 1560
gcagcacccc cacctgctgg cttggcctca aggtgcctcc acccctgccc tccccttcat 1620
cccagggggt ctgactgaga atggagaagg agaagctaca aagtgggcat ccaagccggg 1680
ttctggctgc agaagttctg cctctgcctg gggtcttggc cacattggag aaaaacaggc 1740
tcaaagtggg gctgggacct ggtgggtgaa cctgagctct cccaggagac aacttagctg 1800
ccagtcacca cctatgaggc tcttctaccc cgtgcctgca cctcggccag catctcctat 1860
gctccctggg tcccccagac ctctctgtgt tgtgtgcgtg gcagcctcca ggaataaaca 1920
ttcttgttgt cctttgtaaa aaaaaaaaaa aa 1952
<210> 134
<211> 2688
<212> DNA
<213>Artificial sequence (unknown)
<400> 134
atagagctga tgtatccaga ggttatgttg ctagaggtga gatcagttac ctacgtgcaa 60
ctgaaatttc aaacttctgt tcagcaggga cgtgagtgga caatggtgac tgatagttgg 120
aaatatcagc aaacatctta aattttatac tcaaatgaat gagcaatgaa ccaggagaat 180
aggtccagtt ttttttggct ccttgtaatt tttacctttt tacttaaaat tacagcatct 240
ttttcaatga gtgcctatgt gactgtgact tattacaatg aaaccagcaa ctacactgca 300
atagagacat gtgaatgtgg cgtttatgga ttagcttcac cagtggctaa tgctatggga 360
gtggtaggca tccctaagaa caataactac caagcttgtg accacaacac tgagtttagt 420
aatactaaga agccctggat tgcgctgata gaaagaggta attgtacatt ttcagaaaaa 480
attcaaacag cgggcagaag aaatgctgat gctgttgtga tttacaatgc tccagagact 540
ggcaatcaga cgatacagat ggcaaatttt ggtgcagtag acattgttgc aatcatgatc 600
ggcaatctga aaggcacaaa aattctgcaa tctattcaaa gaggcataca agtgacaatg 660
gtcatagaag tagggaaaaa acatggccct tgggtgaatc actattcaat ttttttcgtt 720
tctgtgtcct tttttattat tacggcggca actgtgggct attttatctt ttattctgct 780
cgaaggctac ggaatgcaag agctcaaagc aggaagcaga ggcaattaaa ggcagatgct 840
aaaaaagcta ttggaaggct tcaactacgc acactgaaac aaggagacaa ggaaattggc 900
cctgatggag atagttgtgc tgtgtgcatt gaattgtata aaccaaatga tttggtacgc 960
atcttaacgt gcaaccatat tttccataag acatgtgttg acccatggct gttagaacac 1020
aggacttgcc ccatgtgcaa atgtgacata ctcaaagctt tgggaattga ggtggatgtt 1080
gaagatggat cagtgtcttt acaagtccct gtatccaatg aaatatctaa tagtgcctcc 1140
tcccatgaag aggataatcg cagcgagacc gcatcatctg gatatgcttc agtacaggga 1200
acagatgaac cgcctctgga ggaacacgtg cagtcaacaa atgaaagtct acagctggta 1260
aaccatgaag caaattctgt ggcagtggat gttattcctc atgttgacaa cccaaccttt 1320
gaagaagacg aaactcctaa tcaagagact gctgttcgag aaattaaatc ttaaaatctg 1380
tgtaaataga aaacttgaac cattagtaat aacagaactg ccaatcaggg cctagtttct 1440
attaataaat tggataaatt taataaaata agagtgatac tgaaagtgct cagatgacta 1500
atattatgct atagttaaat ggcttaaaat atttaacctg ttaacttttt tccacaaact 1560
cattataata tttttcatag gcaagtttcc tctcagtagt gataacaaca tttttagaca 1620
ttcaaaactg tcttcaagaa gtcacgtttt tcatttataa caattttctt ataaaaacat 1680
gttgctttta aaatgtggag tagctgtaat cactttattt tatgatagta tcttaatgaa 1740
aaatactact tctttagctt gggctacatg tgtcagggtt tttctccagg tgcttatatt 1800
gatctggaat tgtaatgtaa aaagcaatgc aaacttaggc gagtacttct tgaaatgtct 1860
atttaagctg ctttaagtta atagaaaaga ttaaagcaaa atattcattt ttactttttc 1920
ttatttttaa aattaggctg aatgtacttc atgtgatttg tcaaccatag tttatcagag 1980
attatggact taattgattg gtatattagt gacatcaact tgacacaaga ttagacaaaa 2040
aattccttac aaaaatactg tgtaactatt tctcaaactt gtgggatttt tcaaaagctc 2100
agtatatgaa tcatcatact gtttgaaatt gctaatgaca gagtaagtaa cactaatatt 2160
ggtcattgat cttcgttcat gaattagtct acagaaaaaa aatgttctgt aaaattagtc 2220
tgttgaaaat gttttccaaa caatgttact ttgaaaattg agtttatgtt tgacctaaat 2280
gggctaaaat tacattagat aaactaaaat tctgtccgtg taactataaa ttttgtgaat 2340
gcattttcct ggtgtttgaa aaagaagggg gggagaattc caggtgcctt aatataaagt 2400
ttgaagcttc atccaccaaa gttaaataga gctatttaaa aatgcacttt atttgtactc 2460
tgtgtggctt ttgttttaga attttgttca aattatagca gaatttaggc aaaaataaaa 2520
cagacatgta tttttgtttg ctgaatggat gaaaccattg cattcttgta cactgatttg 2580
aaatgctgta aatatgtccc aatttgtatt gattctcttt aaatataaaa tgtaaataaa 2640
atattccaat aaaagtttgt gtctggtgtt agtttaaaaa aaaaaaaa 2688
<210> 135
<211> 3440
<212> DNA
<213>Artificial sequence (unknown)
<400> 135
aatgctgctg cctcccagag cagagggagg cagaagagga gggagggaga agagtggaag 60
ggagggggag gcggcacttg ggctgcagct cgcaaccaga ggcagtgtct ctcagctctc 120
ggaaggaccg agagaggcaa ccgcggagta ggatgctctg cggggcgccc agagccgggg 180
gcgcttgaag cagcttcggg gactggggca accgggcagt tttcaccatg catcagtccc 240
tgactcagca gcggtccagc gacatgtccc tgcccgattc catgggagca ttcaatcgga 300
ggaaacgaaa ctccatctat gtcaccgtga ctttgcttat tgtgtccgtg ttaattctca 360
cagtgggcct tgctgcaacc accaggaccc agaatgtgac tgtaggaggt tattaccccg 420
gagttattct cggctttgga tcgttccttg gaatcattgg atcaaacctt attgagaaca 480
aaaggcagat gctggtggct tctatcgtgt ttatcagctt tggtgtgatt gcggcttttt 540
gttgtgccat agttgacggg gtctttgctg ccagacacat tgatctgaaa ccactctacg 600
ctaaccggtg ccattatgtt cccaagacat cacagaagga agctgaggag gttaactgcc 660
ctcacctcag ccgtgaattc tgcacacctc gcatccgggg caacacctgc ttctgctgtg 720
acctctacaa ctgtggcaac cgggtggaga tcactggtgg gtactacgaa tacatcgatg 780
tcagcagttg ccaagatatc atccacctct accacctgct ctggtctgcc accatcctca 840
acattgttgg cctgttcctg ggcatcatca ctgccgctgt ccttggaggc tttaaggaca 900
tgaacccaac tctcccagca ctgaactgtt ctgttgaaaa tacccatcca acagtttctt 960
actatgctca tccccaagtg gcatcctaca atacctacta ccatagccct cctcacctgc 1020
caccatattc tgcttatgac tttcagcatt ccggtgtctt tccatcctcc cctccctctg 1080
gactttctga tgagccccag tctgcctctc cctcacccag ctacatgtgg tcctcaagtg 1140
caccgccccg ttactctcca ccctactatc caccttttga aaagccacca ccttacagtc 1200
cctaaagagg aatgcctgct ggctattgag attattgtgg cttttgtatt tctgcttcag 1260
tggaagtgtg tagggtacaa aatttaaagt gtgactctta tgcataaagt tttacaatgg 1320
cctgccaggc tagggaaaga tagggacgaa gcttattcat tattagtgca gagcaggggt 1380
ggtcaggctg aacgcagcac agaagggcag ctcacattct ctaagcaaga ctggggagcc 1440
agcccagcaa gaagcttgtt tggacttgca ttaccctatg ctccacctct gtattcagca 1500
gaagtgtggt tgccatcttt ttcactttat gtaaaggagt gttgccctcg ggcccttggc 1560
agattgccac cccagcacct aggttgaagc acctggttta taggccctat ctttccctac 1620
ccctaaagtc agtccctaag gacaatttcc cagctgatgg ggctacacag tagttccaat 1680
acagagagtt ctggctaaga ttttgtttgc ttgtgtctgg atgttgaaaa agactgcccg 1740
tatctcttac tccttccttc tctgtgagta ttgtaaaaat ggctgttgtg atcactcagc 1800
tcagcttttg ttattggtac ctcctaaagg gaaaagtgca atattcttgc atcttcagta 1860
gtggggaaca ggatgtattg ttccggaaac actgaaatac acagcaacat gtgagatgtt 1920
ttaagtagat cacttaggag acagtggttc tactacatgt tgcattatta caaaatacat 1980
ttgctacagg agatataaat cttatggttg taattcagag tttaaaaatg ttataaatta 2040
ggttcttggg tcgtgatatg aattgttact aatctttgtg actatttaat cttcaaatat 2100
tgtgcttaac cccagcaatc cgcacgtatc ctgcacccca ccccaaaaga gtcatctgta 2160
ttttaatgcc actggtctta tcggtccttt tgtctgttga gaccagtcat gacagcattc 2220
aagattatga aagtgttaca atgccgcttc aagtctgcaa aacctcaaac gtagccaact 2280
tgacaaatat ttaagtgtta cggcagattt aaaatccatc tggcacaccg tggtaggtat 2340
ttgtacagtt cttttaatta cacatagctt taaaccatca acctgatgag tttaaagctt 2400
ttgcacccat gccttcactt cagaatgaac accttcattg tgatcttatg ttaacctgag 2460
aattgattta aaggaagatt gataatccta tactttataa cgtaaaaata caggggctac 2520
aggagggtac ctaattagac agttctccaa acacagaaca cacactggaa aattttccgg 2580
ccaattttgc tacctcccaa cttgatggat tagaggtagc gcaaatgctg gtgctcccat 2640
ctaccttgta gacacttagc catcaagaat caaggcacaa gaagtgcact ctctcattaa 2700
cagtaaatgt ttgcaagata ttcagtttaa ctttcagcat catgaatgtt cttatccaga 2760
ttttgaatcc gaaaaactat aatcctttta tgttatacaa aattactatg attttttaca 2820
gttctgagca tattaaaatt ctactggatt tcaaaaagag actaataccc aactgactaa 2880
ctaaacaaat atcaacttgt aatactcaat gaattttttt gccatttaca tttgaccgtt 2940
ggctttagtg aatgtccata tttaattttt taaggcacca ttacacagtt tatcctacat 3000
ttatcacatt tcttaaagtg ttaagattct atggctcatt tctatgtatt tttcttactt 3060
tacaaaataa cctgaaacag tatagatttt gtaacactta atttgagcag cttttttatt 3120
acattgaatt atataaagtg catgttacct tagaaaaatt aatatttgct gctttactct 3180
tttgcaaaac atttgctgta atgaatggat ttgtatttcc aatatgtatc ttgactgcat 3240
tttgtaatat ttactgcttt attcctaatt ctgctttaaa gtactgaact gggcatgaaa 3300
cattaaaata ttaatccaga aactgtataa actggatgtt gcttaaaatc tgtatcactg 3360
ccatgttgaa aactcagact gcttttgtga tgtttcaaat gaataaaact atcctcccct 3420
cgttaaaaaa aaaaaaaaaa 3440
<210> 136
<211> 566
<212> DNA
<213>Artificial sequence (unknown)
<400> 136
gccagaaccg gtggagcagc gacccctgag cagtgttctc tgtgctgagc ggcgggactg 60
agctgttgag ttagagccaa catgagtgag cgacaaggtg ctggggcaac caatggaaaa 120
gacaagacat ctggtgaaaa tgatggacag aagaaagttc aagaagaatt tgacattgac 180
atggatgcac cagagacaga acgtgcagcg gtggccattc agtctcagtt cagaaaattc 240
cagaagaaga aggctgggtc tcagtcctag tgggagaacc ccctcctagt ccacctgaaa 300
acaccaaatt caaccatcat ctgtcaagaa attaaaagaa caacacccta gagagaagtc 360
atccacacac aatccacaca cgcatagcaa acctccaatg catgtacaga aacctgtgat 420
atttataccc ttgtaggaag gtatagacaa tggaattgtg agtagcttaa tctctatgtt 480
tctctccatt ttcattcctc ctgcaactat tttccttgat gttgtaataa aatgaagtta 540
cgatgagtga attcaaaaaa aaaaaa 566
<210> 137
<211> 1352
<212> DNA
<213>Artificial sequence (unknown)
<400> 137
agatagaatc tgcagtgcct gaaatccagc ctgctgctta ctcacatcct catactcagc 60
tgcagactgc ctgacagaag ggctgccaaa ctgcactcca gacagacagg tgcacagcca 120
ggcctgattc agcaggaagc atctcagaca ccaaccacta tgctgtcagc agttgcccgg 180
ggctaccagg gctggtttca tccctgtgct aggctttctg tgaggatgag cagcaccggg 240
atagacagga agggcgtcct ggctaaccgg gtagccgtgg tcacggggtc caccagtggg 300
atcggctttg ccatcgcccg acgtctggcc cgggacgggg cccacgtggt catcagcagc 360
cggaagcagc agaacgtgga ccgggccatg gccaagctgc agggggaggg gctgagtgtg 420
gcgggcattg tgtgccacgt ggggaaggct gaggaccggg agcagctggt ggccaaggcc 480
ctggagcact gtgggggcgt cgacttcctg gtgtgcagcg caggggtcaa ccctctggta 540
gggagcactc tggggaccag tgagcagatc tgggacaagg gacctcaggg tggtacccac 600
ttctgacatc tggaccactt cttgcagtca ttgggggtca tcccccacac tggtaacctg 660
tcatcaaatg ggccacagca acattcagct taagtatttc tccttcccac atccaaggga 720
ttgagtggga gtgagattgg ggggtggaaa aaacagtgaa cagtcctggt gagttgcaga 780
tgtggtctca ttccctagag atgcaggatg cagctgacct gaatcaggac agatccctgc 840
aggagggact cctggtgcca tgtcagtccc acctggcact gccctagctc ccaggctccg 900
cctctgcatc tttccttgct acttcctctt tcacttctcc cccgttccca gacccaccag 960
acagagcttc cagagtgtca ggacatgtgt gacttagccc agattcagac tttagtcaca 1020
agcaggatca gcatagacat ctagctccca gcatggcaat tctctgttgt gtctccctgt 1080
ttgtattggc tgcaggaaag ctcagagcca agtctgcgat aagctggtgt gtgtaggccc 1140
ttacagcctg catttttatg accaaataat agaataaatg ctcagtcctt atcacatgct 1200
gtgaactgta ggcaccaacc tcactcttgc tttttcttat ttttctacac tgatttttcc 1260
ttttctccat ttcttcacac atagtaccta tttgatttat tttatgctgt tgcattgtga 1320
gtatgcctta aattctatgg ggacaaggta ag 1352
<210> 138
<211> 2147
<212> DNA
<213>Artificial sequence (unknown)
<400> 138
gatttgtaag tttacctgtt gcagccaata gcagggccat ctcagccagc cagcactgga 60
tactatctgg ccagaagtag caaagcagct cttatttgaa aaaccactgg gttccgagtt 120
cattactaca ggaaaaactg ttctcttctg tggcacagag aaccctgctt caaagcagaa 180
gtagcagttc cggagtccag ctggctaaaa ctcatcccag aggataatgg caacccatgc 240
cttagaaatc gctgggctgt ttcttggtgg tgttggaatg gtgggcacag tggctgtcac 300
tgtcatgcct cagtggagag tgtcggcctt cattgaaaac aacatcgtgg tttttgaaaa 360
cttctgggaa ggactgtgga tgaattgcgt gaggcaggct aacatcagga tgcagtgcaa 420
aatctatgat tccctgctgg ctctttctcc ggacctacag gcagccagag gactgatgtg 480
tgctgcttcc gtgatgtcct tcttggcttt catgatggcc atccttggca tgaaatgcac 540
caggtgcacg ggggacaatg agaaggtgaa ggctcacatt ctgctgacgg ctggaatcat 600
cttcatcatc acgggcatgg tggtgctcat ccctgtgagc tgggttgcca atgccatcat 660
cagagatttc tataactcaa tagtgaatgt tgcccaaaaa cgtgagcttg gagaagctct 720
ctacttagga tggaccacgg cactggtgct gattgttgga ggagctctgt tctgctgcgt 780
tttttgttgc aacgaaaaga gcagtagcta cagatactcg ataccttccc atcgcacaac 840
ccaaaaaagt tatcacaccg gaaagaagtc accgagcgtc tactccagaa gtcagtatgt 900
gtagttgtgt atgttttttt aactttacta taaagccatg caaatgacaa aaatctatat 960
tactttctca aaatggaccc caaagaaact ttgatttact gttcttaact gcctaatctt 1020
aattacagga actgtgcatc agctatttat gattctataa gctatttcag cagaatgaga 1080
tattaaaccc aatgctttga ttgttctaga aagtatagta atttgttttc taaggtggtt 1140
caagcatcta ctctttttat catttacttc aaaatgacat tgctaaagac tgcattattt 1200
tactactgta atttctccac gacatagcat tatgtacata gatgagtgta acatttatat 1260
ctcacataga gacatgctta tatggtttta tttaaaatga aatgccagtc cattacactg 1320
aataaataga actcaactat tgcttttcag ggaaatcatg gatagggttg aagaaggtta 1380
ctattaattg tttaaaaaca gcttagggat taatgtcctc catttataat gaagattaaa 1440
atgaaggctt taatcagcat tgtaaaggaa attgaatggc tttctgatat gctgtttttt 1500
agcctaggag ttagaaatcc taacttcttt atcctcttct cccagaggct ttttttttct 1560
tgtgtattaa attaacattt ttaaaaagca gatattttgt caaggggctt tgcattcaaa 1620
ctgcttttcc agggctatac tcagaagaaa gataaaagtg tgatctaaga aaaagtgatg 1680
gttttaggaa agtgaaaata tttttgtttt tgtatttgaa gaagaatgat gcattttgac 1740
aagaaatcat atatgtatgg atatatttta ataagtattt gagtacagac tttgaggttt 1800
catcaatata aataaaagag cagaaaaata tgtcttggtt ttcatttgct taccaaaaaa 1860
acaacaacaa aaaaagttgt cctttgagaa cttcacctgc tcctatgtgg gtacctgagt 1920
caaaattgtc atttttgttc tgtgaaaaat aaatttcctt cttgtaccat ttctgtttag 1980
ttttactaaa atctgtaaat actgtatttt tctgtttatt ccaaatttga tgaaactgac 2040
aatccaattt gaaagtttgt gtcgacgtct gtctagctta aatgaatgtg ttctatttgc 2100
tttatacatt tatattaata aattgtacat ttttctaatt atttgaa 2147
<210> 139
<211> 2654
<212> DNA
<213>Artificial sequence (unknown)
<400> 139
tcatcgtagg aggttccagc tcagtgccca gagacagccc ccacatccca ccccatcagg 60
tcagctcagg ctggagcagg catatgagca acacccctca ttccaccccc atacacatgc 120
ataagcccat ccgcctgcgc cctgccagtc tgaccagcac agtcctgggg acaggagcgt 180
ggtggaggag ctgcaggtgg gggccagaga agcctccaca gagagcaaaa gccagggtca 240
gccagagaca ggacaccaga agagacagga gatcagagac cagaggaaca gagaagaggc 300
cccagagcaa ggcaaggaac ggccaaggca ccaggacatg gatgcagtgg agccaggggg 360
acgtggctgg gccagcatgt tggcgtgcag gctttggaaa gccatcagca gggcgctgtt 420
tgcagagttc ctggccacgg ggctgtatgt gttctttggc gtgggctcag tcatgcgctg 480
gcccacagca cttccctccg tgctacagat tgccatcacc ttcaacctgg tcaccgccat 540
ggctgtgcag gtcacctgga aggccagcgg ggcccacgcc aaccccgccg tgacgctggc 600
cttcctcgta ggctcccaca tctctctgcc ccgtgctgtg gcctatgtgg ctgcccagct 660
ggtgggggcc acggtggggg ctgctctgct ttatggggtc atgccgggag acatccgaga 720
gacccttggg atcaacgtgg tccggaacag tgtctcaact ggccaggcgg tggcagtgga 780
gctgcttctg accctgcagc tggtgctctg tgtcttcgct tccaccgaca gccgtcagac 840
atcaggctcc ccggccacca tgattgggat ctctgtggca ctgggccacc tcattgggat 900
ccacttcact ggctgctcca tgaatccagc ccgctccttc ggccctgcca tcatcattgg 960
gaagttcaca gtccactggg tcttctgggt ggggcccctg atgggagccc tcctggcctc 1020
actgatctac aacttcgtcc tgttccccga caccaagacc ctggcgcagc ggctggctat 1080
cctcacaggc accgtagagg tggggacagg ggcaggggca ggggcggagc ccctgaagaa 1140
ggaatcccag ccgggttcgg gagccgtgga gatggagagt gtgtgaaaca gcctacgcct 1200
ggccgcgccc ttgggcttcc tgccttgcag gacctgcctg gaggttctcc ctgggggtgg 1260
cgggaggggg aggcttgacc ttttgtcctg accaggtggg ctggagggga caagccctat 1320
ccctggcatt acgtttctag gtagaatctg ggagtgaatt tgtcccattc cctctctgta 1380
gggcttcccc acctctcggt gggacagagc agaggaaggc aggggattta ggatcgccct 1440
cccatcctct cacccactgg accccgtagg agtcctgacc ccagatgccc aagtcttggg 1500
ggagaaagga atgggagccc agacagccac tctgcttaga catgggagct atagggacct 1560
cagggagccc cagcttctta cccacccagg aaacccttgg tccagagagg acaggctttc 1620
tggaggaatc aggccctggg acagcctctg agctcctggg ggtgtttctc tgaccttggg 1680
tgtggttttg ggggctatat ttcctccttc agactggggg cttcctgagg acagagactg 1740
ctctaccaat agatctttgt ttgttttgag acagaatctt gatctgttac ccaggctgga 1800
gtgcagtggc atgatctcgg ctcactgcaa cctctacctc ctgggttcaa gggattctcc 1860
tgcctcagcc tcccaagtag ctgggattac aggcgcctgc caccacgccc agctaatttt 1920
ttgtattttt agtagagatg gggtttcatc atattggtca gggtggtctc aaactcctga 1980
cctgaggcga tctgcccacc tcggcctccc aaagtgctgg gattacaggc gtgagccacc 2040
gtgcccggcc tctcccaata ggtctttatt cctcaatcct ccaaatgctc tggagaggcc 2100
cccacccttg agaagaactg acacagagaa gaacattttc tcaggctcgt agagaggtgg 2160
gatagaggaa gggaggtttg agccagacag gcctttccca gggaagcctc ctcccaggtg 2220
cttgccccag ctcccacccc acagcccact ctcaggcagg aacaatcctc agaggggaag 2280
tgcccatcta gccattgact catgacctgg gtcaaagaag ccgtctccag gctctctgtc 2340
agcattacag gatccccaga aagctgttga ataagcccta agggtggtag gaacccagga 2400
gggacccagg aaactaagat ttgagattca gtgcctctga aagactacca aaatctaagt 2460
tggtttaata gttaaaagct gctgtagatt tattctgccc acaacttggg ggtcctttct 2520
ggatctcggc ttctccagct gtaaaatgga cacacaatcc tcctccaggg actgctgtga 2580
aatcaagaaa tcggaaaata ctttcagaag ttaaaatgct agaaaaacaa ccccaataaa 2640
tgatgattat tgtt 2654
<210> 140
<211> 3885
<212> DNA
<213>Artificial sequence (unknown)
<400> 140
agagccggac ggggtaaact gagcggcggc ggcggggcgc tggggcggag actgcgaccc 60
ggagccgccc ggactgacgg agcccactgc ggtgcgggcg ttggcgcggg cacggaggac 120
ccgggcaggc atcgcaagcg accccgagcg gagccccgga gccatggccc tgagcgagct 180
ggcgctggtc cgctggctgc aggagagccg ccgctcgcgg aagctcatcc tgttcatcgt 240
gttcctggcg ctgctgctgg acaacatgct gctcactgtc gtggtcccca tcatcccaag 300
ttatctgtac agcattaagc atgagaagaa tgctacagaa atccagacgg ccaggccagt 360
gcacactgcc tccatctcag acagcttcca gagcatcttc tcctattatg ataactcgac 420
tatggtcacc gggaatgcta ccagagacct gacacttcat cagaccgcca cacagcacat 480
ggtgaccaac gcgtccgctg ttccttccga ctgtcccagt gaagacaaag acctcctgaa 540
tgaaaacgtg caagttggtc tgttgtttgc ctcgaaagcc accgtccagc tcatcaccaa 600
ccctttcata ggactactga ccaacagaat tggctatcca attcccatat ttgcgggatt 660
ctgcatcatg tttgtctcaa caattatgtt tgccttctcc agcagctatg ccttcctgct 720
gattgccagg tcgctgcagg gcatcggctc gtcctgctcc tctgtggctg ggatgggcat 780
gcttgccagt gtctacacag atgatgaaga gagaggcaac gtcatgggaa tcgccttggg 840
aggcctggcc atgggggtct tagtgggccc ccccttcggg agtgtgctct atgagtttgt 900
ggggaagacg gctccgttcc tggtgctggc cgccctggta ctcttggatg gagctattca 960
gctctttgtg ctccagccgt cccgggtgca gccagagagt cagaagggga cacccctaac 1020
cacgctgctg aaggacccgt acatcctcat tgctgcaggc tccatctgct ttgcaaacat 1080
gggcatcgcc atgctggagc cagccctgcc catctggatg atggagacca tgtgttcccg 1140
aaagtggcag ctgggcgttg ccttcttgcc agctagtatc tcttatctca ttggaaccaa 1200
tatttttggg atacttgcac acaaaatggg gaggtggctt tgtgctcttc tgggaatgat 1260
aattgttgga gtcagcattt tatgtattcc atttgcaaaa aacatttatg gactcatagc 1320
tccgaacttt ggagttggtt ttgcaattgg aatggtggat tcgtcaatga tgcctatcat 1380
gggctacctc gtagacctgc ggcacgtgtc cgtctatggg agtgtgtacg ccattgcgga 1440
tgtggcattt tgtatggggt atgctatagg tccttctgct ggtggtgcta ttgcaaaggc 1500
aattggattt ccatggctca tgacaattat tgggataatt gatattcttt ttgcccctct 1560
ctgctttttt cttcgaagtc cacctgccaa agaagaaaaa atggctattc tcatggatca 1620
caactgccct attaaaacaa aaatgtacac tcagaataat atccagtcat atccgatagg 1680
tgaagatgaa gaatctgaaa gtgactgaga tgagatcctc aaaaatcatc aaagtgttta 1740
attgtataaa acagtgtttc cagtgacaca actcatccag aactgtctta gtcataccat 1800
ccatccctgg tgaaagagta aaaccaaagg ttattatttc ctttccatgg ttatggtcga 1860
ttgccaacag ccttataaag aaaaagaagc ttttctaggg gtttgtataa atagtgttga 1920
aactttattt tatgtattta attttattaa atatcataca atatattttg atgaaatagg 1980
tattgtgtaa atctataaat atttgaatcc aaaccaaata taatttttta acttacatta 2040
acaaacattt gggcaaaaat catattggta atgagtgttt aaaattaaag cacacattat 2100
ctctgagact cttccaacaa agagaaacta gaatgaagtc tgaaaaacag aatcaagtaa 2160
gacagcatgt tatatagtga cactgaatgt tatttaactt gtagttacta tcaatatatt 2220
tatgcgttaa acagctagtt ctctcaagtg tagaggacaa gaacttgtgt cagttatctt 2280
ttgaatccat aaatcttagc tggcattagt tttctatgta atcacctacc tagagagagt 2340
tgtaaattat atgttaacat gttatctggt tggcagcaaa cactaaagcc aataaaggaa 2400
aaacagtaaa tgttccgaaa gcagagaaaa gcaaccaaac atattgttat gaactaaaag 2460
ctttcccttt aagatgcata cttgtcttac tggatgaaga aaattgaggg tacatgtacc 2520
ttatactgtc aaggttgttt aaacatgata aggttaatcg ccatctactt caagttttag 2580
aaaaggaaac aagaagctga aaacagctgc tctgacttta atatctgact atatctttga 2640
tctgtttgca ggtcatccaa gtgttttcta ggaatatatt tattttaggt tgtctgaaac 2700
tactattttt tagactcctg aaagttgttc acatcaatgt gaagacaaat tttaaatgaa 2760
aatgaagaat gaaattatgt cttgaatcat atattaagaa gtaaaaataa tagtgatcag 2820
gcagaaaaga aaaatggaac atctaaaaat gtatgtgcta actatatcat ccagtgtgca 2880
gtgttgtgta tttttctaag catgacaaca ttgatgtgcc ttttcagtgt aacagcaaat 2940
actgttagtg aacattgtca atttatgtca ttttgttaag agatatgact ggagtgtgca 3000
gtgtggaatg tctctaatac tacttgtgaa tcctgcagtt ctataatcat aaacaaaaat 3060
tacttagttt cgttaagcta agattgtgtt tgtgttaact tcgacatcaa ggagcaaaga 3120
actttagaac agactcctca atcttgtgac tttcttattc tctaggaaag taacacttcg 3180
tttcatgaag cttttctgtg gggcttcgat tatttcaagt ctggtttcta agtgcagtgt 3240
gtttgaagca aacgaacttc caactcactt atttggcatt gggcaacttg gccaagtctg 3300
ccactttgga agatggctct ggaggaaact ctcatatggc taaaaaggca ggctagtttc 3360
ttacttctac aggggtagag ccttaaaaaa gaacgtgcta caaattggtt ctctttgagg 3420
gtttctggtt ctccctgccc ccaataccat atactttatt gcaattttat ttttgccttt 3480
acggctctgt gtctttctgc aagaaggcct ggcaaaggta tgcctgctgt tggtccctcg 3540
ggataagata aaatataaat aaaaccttca gaactgtttt ggagcaaaag atagcttgta 3600
cttggggaaa aaaattctaa gttcttttat atgactaata ttcttggtta gcaagactgg 3660
aaagaggtgt ttttttaaaa tgtacatacc agaacaaaga acatacagct ctctgaacat 3720
ttattttttg aacagaggtg gtttttatgt ttggacctgg taatacagat acaaaaactt 3780
taatgaggta gcaatgaata ttcaactgtt tgactgctaa gtgtatctgt ccatatttta 3840
gcaagtttac ttaataaatc ttctgaacca tgaaaaaaaa aaaaa 3885
<210> 141
<211> 1753
<212> DNA
<213>Artificial sequence (unknown)
<400> 141
cagccccgcc cctacctgtg gaagcccagc cgcccgctcc cgcggataaa aggcgcggag 60
tgtccccgag gtcagcgagt gcgcgctcct cctcgcccgc cgctaggtcc atcccggccc 120
agccaccatg tccatccact tcagctcccc ggtattcacc tcgcgctcag ccgccttctc 180
gggccgcggc gcccaggtgc gcctgagctc cgctcgcccc ggcggccttg gcagcagcag 240
cctctacggc ctcggcgcct cacggccgcg cgtggccgtg cgctctgcct atgggggccc 300
ggtgggcgcc ggcatccgcg aggtcaccat taaccagagc ctgctggccc cgctgcggct 360
ggacgccgac ccctccctcc agcgggtgcg ccaggaggag agcgagcaga tcaagaccct 420
caacaacaag tttgcctcct tcatcgacaa ggtgcggttt ctggagcagc agaacaagct 480
gctggagacc aagtggacgc tgctgcagga gcagaagtcg gccaagagca gccgcctccc 540
agacatcttt gaggcccaga ttgctggcct tcggggtcag cttgaggcac tgcaggtgga 600
tgggggccgc ctggaggcgg agctgcggag catgcaggat gtggtggagg acttcaagaa 660
taagtacgaa gatgaaatta accaccgcac agctgctgag aatgagtttg tggtgctgaa 720
gaaggatgtg gatgctgcct acatgagcaa ggtggagctg gaggccaagg tggatgccct 780
gaatgatgag atcaacttcc tcaggaccct caatgagacg gagttgacag agctgcagtc 840
ccagatctcc gacacatctg tggtgctgtc catggacaac agtcgctccc tggacctgga 900
cggcatcatc gctgaggtca aggcgcagta tgaggagatg gccaaatgca gccgggctga 960
ggctgaagcc tggtaccaga ccaagtttga gaccctccag gcccaggctg ggaagcatgg 1020
ggacgacctc cggaataccc ggaatgagat ttcagagatg aaccgggcca tccagaggct 1080
gcaggctgag atcgacaaca tcaagaacca gcgtgccaag ttggaggccg ccattgccga 1140
ggctgaggag cgtggggagc tggcgctcaa ggatgctcgt gccaagcagg aggagctgga 1200
agccgccctg cagcggggca agcaggatat ggcacggcag ctgcgtgagt accaggaact 1260
catgagcgtg aagctggccc tggacatcga gatcgccacc taccgcaagc tgctggaggg 1320
cgaggagagc cggttggctg gagatggagt gggagccgtg aatatctctg tgatgaattc 1380
cactggtggc agtagcagtg gcggtggcat tgggctgacc ctcgggggaa ccatgggcag 1440
caatgccctg agcttctcca gcagtgcggg tcctgggctc ctgaaggctt attccatccg 1500
gaccgcatcc gccagtcgca ggagtgcccg cgactgagcc gcctcccacc actccactcc 1560
tccagccacc acccacaatc acaagaagat tcccacccct gcctcccatg cctggtccca 1620
agacagtgag acagtctgga aagtgatgtc agaatagctt ccaataaagc agcctcattc 1680
tgaggcctga gtgatccacg tgaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1740
aaaaaaaaaa aaa 1753
<210> 142
<211> 2352
<212> DNA
<213>Artificial sequence (unknown)
<400> 142
ggtggagaca gggccggctg tggtcagtga caaatgctgg ctgcaatcca gccagccctc 60
tgccctttct gagcccgagg gactgccacc tccactgtgt gcacactcag ctacgggaca 120
catttcaggt atccaaggca gcagaggtga gtgggtcccc cgagctctgt gaccttatgc 180
tccacactaa ctctggcaga gcctccgttt cctcatagaa caaagaacag ccaccatgca 240
gctcttcctc ctcttgtgcc tggtgcttct cagccctcag ggggcctccc ttcaccgcca 300
ccacccccgg gagatgaaga agagagtcga ggacctccat gtaggtgcca cggtggcccc 360
cagcagcaga agggacttta cctttgacct ctacagggcc ttggcttccg ctgcccccag 420
ccagagcatc ttcttctccc ctgtgagcat ctccatgagc ctggccatgc tctccctggg 480
ggctgggtcc agcacaaaga tgcagatcct ggagggcctg ggcctcaacc tccagaaaag 540
ctcagagaag gagctgcaca gaggctttca gcagctcctt caggaactca accagcccag 600
agatggcttc cagctgagcc tcggcaatgc ccttttcacc gacctggtgg tagacctgca 660
ggacaccttc gtaagtgcca tgaagacgct gtacctggca gacactttcc ctaccaactt 720
tagggactct gcaggggcca tgaagcagat caatgattat gtggcaaagc aaacgaaggg 780
caagattgtg gacttgctta agaacctcga tagcaatgcg gtcgtgatca tggtgaatta 840
catcttcttt aaagctaagt gggagacaag cttcaaccac aaaggcaccc aagagcaaga 900
cttctacgtg acctcggaga ctgtggtgcg ggtacccatg atgagccgcg aggatcagta 960
tcactacctc ctggaccgga acctctcctg cagggtggtg ggggtcccct accaaggcaa 1020
tgccacggct ttgttcattc tccccagtga gggaaagatg cagcaggtgg agaatggact 1080
gagtgagaaa acgctgagga agtggcttaa gatgttcaaa aagaggcagc tcgagcttta 1140
ccttcccaaa ttctccattg agggctccta tcagctggag aaagtcctcc ccagtctggg 1200
gatcagtaac gtcttcacct cccatgctga tctgtccggc atcagcaacc actcaaatat 1260
ccaggtgtct gagatggtgc acaaagctgt ggtggaggtg gacgagtcgg gaaccagagc 1320
agcggcagcc acggggacaa tattcacttt caggtcggcc cgcctgaact ctcagaggct 1380
agtgttcaac aggccctttc tgatgttcat tgtggataac aacatcctct tccttggcaa 1440
agtgaaccgc ccctgaggtg gggcttctcc tgaaatctac aggcctcagg gtgggagatg 1500
aagggggcta agctatggcc catctgtatg ctggtagcta gtgatttaca caggtttagt 1560
tgactaatga ggcattacaa ataatattac tctatgatga ttgcttccac ccacacgact 1620
gcaacataca ggtgccttgg ggaaatgtgg agaacattca atcttgccgt cactattcat 1680
caatgaagat taacactgag atccagagag gctggatgac ttgctcaagt tcaccagcat 1740
ggtagtggca aagagaggtc cagagtcctg gcccttgatg cccagctcag tgccacaaag 1800
ctcaatagga gggatgttcc agtggatgag ggccaccagg aagcacaggt ccaaggctgg 1860
tcccacactt atcagcagca acaactgtca gttcatcctg catgggaaaa atgttggaat 1920
gggagtctga aatggggcta ctgtttcagt cctaatgtgc tgtgtgacat tgggacaaca 1980
ctttccctct ctggacctca gtttccctct gtatacaagg atcagattct tgctgtgacc 2040
caagaactcc tgaaatcata tagaaaggct ggggtgggcc ctgtcattcg tggttgattt 2100
caatacactc aagtgccatt catcctttaa gaaaaacatc tggatatcaa ggtggaaatg 2160
gcccatttaa tgattgatta tatcattttg tggatatagt tataatctga tgggcctggc 2220
tgggagtgga agaagggaag ccttttgcaa atagtagagt atcagttgca ggtgccaatg 2280
actaactttt tgaattctat gttggcatta acaataaagc attttgcaaa cactggtaaa 2340
aaaaaaaaaa aa 2352
<210> 143
<211> 3681
<212> DNA
<213>Artificial sequence (unknown)
<400> 143
tgtaaatgct cttctgacta atgcaaacca tgtgtccata gaaccagaag atttttccag 60
gggaaaagag cccccacgcc ccgcccagct ataaggggcc atgcaccaag cagggtaccc 120
aggctgcaga ggtgccatgg ctgagtcaca cctgctgcag tggctgctgc tgctgctgcc 180
cacgctctgt ggcccaggca ctgctgcctg gaccacctca tccttggcct gtgcccaggg 240
ccctgagttc tggtgccaaa gcctggagca agcattgcag tgcagagccc tagggcattg 300
cctacaggaa gtctggggac atgtgggagc cgatgaccta tgccaagagt gtgaggacat 360
cgtccacatc cttaacaaga tggccaagga ggccattttc caggacacga tgaggaagtt 420
cctggagcag gagtgcaacg tcctcccctt gaagctgctc atgccccagt gcaaccaagt 480
gcttgacgac tacttccccc tggtcatcga ctacttccag aaccagactg actcaaacgg 540
catctgtatg cacctgggcc tgtgcaaatc ccggcagcca gagccagagc aggagccagg 600
gatgtcagac cccctgccca aacctctgcg ggaccctctg ccagaccctc tgctggacaa 660
gctcgtcctc cctgtgctgc ccggggccct ccaggcgagg cctgggcctc acacacagga 720
tctctccgag cagcaattcc ccattcctct cccctattgc tggctctgca gggctctgat 780
caagcggatc caagccatga ttcccaaggg tgcgctagct gtggcagtgg cccaggtgtg 840
ccgcgtggta cctctggtgg cgggcggcat ctgccagtgc ctggctgagc gctactccgt 900
catcctgctc gacacgctgc tgggccgcat gctgccccag ctggtctgcc gcctcgtcct 960
ccggtgctcc atggatgaca gcgctggccc aaggtcgccg acaggagaat ggctgccgcg 1020
agactctgag tgccacctct gcatgtccgt gaccacccag gccgggaaca gcagcgagca 1080
ggccatacca caggcaatgc tccaggcctg tgttggctcc tggctggaca gggaaaagtg 1140
caagcaattt gtggagcagc acacgcccca gctgctgacc ctggtgccca ggggctggga 1200
tgcccacacc acctgccagg ccctcggggt gtgtgggacc atgtccagcc ctctccagtg 1260
tatccacagc cccgaccttt gatgagaact cagctgtcca gctgcaaagg aaaagccaag 1320
tgagacgggc tctgggacca tggtgaccag gctcttcccc tgctccctgg ccctcgccag 1380
ctgccaggct gaaaagaagc ctcagctccc acaccgccct cctcaccgcc cttcctcggc 1440
agtcacttcc actggtggac cacgggcccc cagccctgtg tcggccttgt ctgtctcagc 1500
tcaaccacag tctgacacca gagcccactt ccatcctctc tggtgtgagg cacagcgagg 1560
gcagcatctg gaggagctct gcagcctcca cacctaccac gacctcccag ggctgggctc 1620
aggaaaaacc agccactgct ttacaggaca gggggttgaa gctgagcccc gcctcacacc 1680
cacccccatg cactcaaaga ttggatttta cagctacttg caattcaaaa ttcagaagaa 1740
taaaaaatgg gaacatacag aactctaaaa gatagacatc agaaattgtt aagttaagct 1800
ttttcaaaaa atcagcaatt ccccagcgta gtcaagggtg gacactgcac gctctggcat 1860
gatgggatgg cgaccgggca agctttcttc ctcgagatgc tctgctgctt gagagctatt 1920
gctttgttaa gatataaaaa ggggtttctt tttgtctttc tgtaaggtgg acttccagct 1980
tttgattgaa agtcctaggg tgattctatt tctgctgtga tttatctgct gaaagctcag 2040
ctggggttgt gcaagctagg gacccattcc tgtgtaatac aatgtctgca ccaatgctaa 2100
taaagtccta ttctctttta tgagaaagaa aaagacaccg tcctttaaag tgctgcagta 2160
tggccagacg tggtggctca cacctgcaat cccagcacct taggaggccg aggcaggagg 2220
atccttgagg tcaggagttc gagaccagcc tcgccaacat ggtgaaaccc catttctact 2280
aaaaatacaa aaaattagcc aagtgtggtg gcatatgcct gtaatcccaa ctactcagaa 2340
ggccgaggca ggagaattac ttgaacgcag gagaatcact gcagcccagg aggcagaggt 2400
tgcagtgagc cgagattgca ccactgcact ccagcctggg tgacagagca agactccatc 2460
tcagtaaata aataaataaa taaaaagcgc tgcagtagct gtggcctcac cctgaagtca 2520
gcgggcccag gcctacctca ctctctccct tggcagagaa gcagacgtcc atagctcctc 2580
tccctcacaa gcgctcccag cctgccctcc agctgctgct ctcccctccc agtctctact 2640
cactgggatg aggttaggtc atgaggacac caaaaaccta aaaataaaca aaaagccaaa 2700
caagccttag cttttcttaa agactgaaat gcctggaagt gtccctttat ttataaaata 2760
acttttgtca tatttcttat acatgtttct tgtaagaaat tcagaaacta cagacaaaga 2820
gagtggaaat tacccactgt caggcctctg agcccaagct aagccatcat atcccctgtg 2880
ccctgcacgt atacacccag atggcctgaa gcaactgaag atccacaaaa gaagtgaaaa 2940
tagccagttc ctgccttaac tgatgacatt ccaccattgt gatttgttcc tgccccaccc 3000
taactgatca attgaccttg tgacaataca ccttccccac ccttgagaag gtgctttgta 3060
atattctccc cacccacccc acgcccgcac ccccgcaccc ttaagaaggt attttgtaat 3120
attctctccg ccattgagaa tgtgctttgt aagatccacc ccctgcccac aaaaaattgc 3180
tcctaactcc accgcctatc ccaaacctac aagaactaat gataatccca ccaccctttg 3240
ctgactcttt ttggactcag cccacctgca cccaggtgat taaaaagctt tattgttcac 3300
acaaagcctg tttggtagtc tcttcacagg gaagcatgtg acacccacaa tcccacctag 3360
cccaggagag agctacggca gggtgtgtgt tttgacactg agcttggggc tttttccatc 3420
ttctccccac agcctctggc tccacacctc caccgttcaa gcgccagaaa gagctgtcta 3480
tgcagcctgc tcttgggcct ggggatgaga cacacaattc attggctcct ggattttaag 3540
tagacatttg taaatctata gctaactact gtccttaaag ccattgtttc cattacaaaa 3600
tccaactctc tgagagaaaa gggtgtttta aatttaaaaa aataaaaaca aaaaagtttg 3660
attgagaaaa aaaaaaaaaa a 3681
<210> 144
<211> 484
<212> DNA
<213>Artificial sequence (unknown)
<400> 144
tcccttcagt tccgtcgacg aggttgtgca atccaccagt cttataaata cagtgacgct 60
ccagcctctg gaagcctctg tcagctcagc ctccaaagga gccagcgtct ccccagttcc 120
tgaaatcctg ggtgttgcct gccagtcgcc atgagaactt cctaccttct gctgtttact 180
ctctgcttac ttttgtctga gatggcctca ggtggtaact ttctcacagg ccttggccac 240
agatctgatc attacaattg cgtcagcagt ggagggcaat gtctctattc tgcctgcccg 300
atctttacca aaattcaagg cacctgttac agagggaagg ccaagtgctg caagtgagct 360
gggagtgacc agaagaaatg acgcagaagt gaaatgaact ttttataagc attcttttaa 420
taaaggaaaa ttgcttttga agtatacctc ctttgggcca aaaaaaaaaa aaaaaaaaaa 480
aaaa 484
<210> 145
<211> 1153
<212> DNA
<213>Artificial sequence (unknown)
<400> 145
tcttctgccc cgggctcccc tgctcttaac ccgcgcgcgg gggcgcccag gccactgggc 60
tccgcggagc cagcgagagg tctgcgcgga gtctgagcgg cgctcgtccc gtcccaaggc 120
cgacgccagc acgccgtcat ggcccccgca gcggcgacgg ggggcagcac cctgcccagt 180
ggcttctcgg tcttcaccac cttgcccgac ttgctcttca tctttgagtt tatcttcggg 240
ggcctggtgt ggatcctggt ggcctcctcc ctggtgccct ggcccctggt ccagggctgg 300
gtgatgttcg tgtctgtgtt ctgcttcgtg gccaccacca ccttgatcat cctgtacata 360
attggagccc acggtggaga gacttcctgg gtcaccttgg acgcagccta ccactgcacc 420
gctgccctct tttacctcag cgcctcagtc ctggaggccc tggccaccat cacgatgcaa 480
gacggcttca cctacaggca ctaccatgaa aacattgctg ccgtggtgtt ctcctacata 540
gccactctgc tctacgtggt ccatgcggtg ttctctttaa tcagatggaa gtcttcataa 600
agccgcagta gaacttgagc tgaaaaccca gatggtgtta actggccgcc ccactttccg 660
gcataacttt ttagaaaaca gaaatgccct tgatggtgga aaaaagaaaa caaccacccc 720
cccactgccc aaaaaaaaaa gccctgccct gttgctcgtg ggtgctgtgt ttactctccc 780
gtgtgccttc gcgtccgggt tgggagcttg ctgtgtctaa cctccaactg ctgtgctgtc 840
tgctagggtc acctcctgtt tgtgaaaggg gaccttcttg ttcgggggtg ggaagtggcg 900
accgtgacct gagaaggaaa gaaagatcct ctgctgaccc ctggagcagc tctcgagaac 960
tacctgttgg tattgtccac aagctctccc gagcgcccca tcttgtgcca tgttttaagt 1020
cttcatggat gttctgcatg tcatggggac taaaactcac ccaacagatc tttccagagg 1080
tccatggtgg aagacgataa ccctgtgaaa tactttataa aatgtcttaa tgttcaaaaa 1140
aaaaaaaaaa aaa 1153
<210> 146
<211> 1791
<212> DNA
<213>Artificial sequence (unknown)
<400> 146
ataaaaaccg tcctcgggcg cggcggggag aagccgagct gagcggatcc tcacacgact 60
gtgatccgat tctttccagc ggcttctgca accaagcggg tcttaccccc ggtcctccgc 120
gtctccagtc ctcgcacctg gaaccccaac gtccccgaga gtccccgaat ccccgctccc 180
aggctaccta agaggatgag cggtgctccg acggccgggg cagccctgat gctctgcgcc 240
gccaccgccg tgctactgag cgctcagggc ggacccgtgc agtccaagtc gccgcgcttt 300
gcgtcctggg acgagatgaa tgtcctggcg cacggactcc tgcagctcgg ccaggggctg 360
cgcgaacacg cggagcgcac ccgcagtcag ctgagcgcgc tggagcggcg cctgagcgcg 420
tgcgggtccg cctgtcaggg aaccgagggg tccaccgacc tcccgttagc ccctgagagc 480
cgggtggacc ctgaggtcct tcacagcctg cagacacaac tcaaggctca gaacagcagg 540
atccagcaac tcttccacaa ggtggcccag cagcagcggc acctggagaa gcagcacctg 600
cgaattcagc atctgcaaag ccagtttggc ctcctggacc acaagcacct agaccatgag 660
gtggccaagc ctgcccgaag aaagaggctg cccgagatgg cccagccagt tgacccggct 720
cacaatgtca gccgcctgca ccatggaggc tggacagtaa ttcagaggcg ccacgatggc 780
tcagtggact tcaaccggcc ctgggaagcc tacaaggcgg ggtttgggga tccccacggc 840
gagttctggc tgggtctgga gaaggtgcat agcatcacgg gggaccgcaa cagccgcctg 900
gccgtgcagc tgcgggactg ggatggcaac gccgagttgc tgcagttctc cgtgcacctg 960
ggtggcgagg acacggccta tagcctgcag ctcactgcac ccgtggccgg ccagctgggc 1020
gccaccaccg tcccacccag cggcctctcc gtacccttct ccacttggga ccaggatcac 1080
gacctccgca gggacaagaa ctgcgccaag agcctctctg gaggctggtg gtttggcacc 1140
tgcagccatt ccaacctcaa cggccagtac ttccgctcca tcccacagca gcggcagaag 1200
cttaagaagg gaatcttctg gaagacctgg cggggccgct actacccgct gcaggccacc 1260
accatgttga tccagcccat ggcagcagag gcagcctcct agcgtcctgg ctgggcctgg 1320
tcccaggccc acgaaagacg gtgactcttg gctctgcccg aggatgtggc cgttccctgc 1380
ctgggcaggg gctccaagga ggggccatct ggaaacttgt ggacagagaa gaagaccacg 1440
actggagaag ccccctttct gagtgcaggg gggctgcatg cgttgcctcc tgagatcgag 1500
gctgcaggat atgctcagac tctagaggcg tggaccaagg ggcatggagc ttcactcctt 1560
gctggccagg gagttgggga ctcagaggga ccacttgggg ccagccagac tggcctcaat 1620
ggcggactca gtcacattga ctgacgggga ccagggcttg tgtgggtcga gagcgccctc 1680
atggtgctgg tgctgttgtg tgtaggtccc ctggggacac aagcaggcgc caatggtatc 1740
tgggcggagc tcacagagtt cttggaataa aagcaacctc agaacacttt g 1791
<210> 147
<211> 863
<212> DNA
<213>Artificial sequence (unknown)
<400> 147
agggccaccc aggtgagcct ctcactcgcc acctcctctt ccacccctgc caggcccagc 60
agccaccaca gcgcctgctt cctcggccct gaaatcatgc ccctaggtct cctgtggctg 120
ggcctagccc tgttgggggc tctgcatgcc caggcccagg actccacctc agacctgatc 180
ccagccccac ctctgagcaa ggtccctctg cagcagaact tccaggacaa ccaattccag 240
gggaagtggt atgtggtagg cctggcaggg aatgcaattc tcagagaaga caaagacccg 300
caaaagatgt atgccaccat ctatgagctg aaagaagaca agagctacaa tgtcacctcc 360
gtcctgttta ggaaaaagaa gtgtgactac tggatcagga cttttgttcc aggttgccag 420
cccggcgagt tcacgctggg caacattaag agttaccctg gattaacgag ttacctcgtc 480
cgagtggtga gcaccaacta caaccagcat gctatggtgt tcttcaagaa agtttctcaa 540
aacagggagt acttcaagat caccctctac gggagaacca aggagctgac ttcggaacta 600
aaggagaact tcatccgctt ctccaaatct ctgggcctcc ctgaaaacca catcgtcttc 660
cctgtcccaa tcgaccagtg tatcgacggc tgagtgcaca ggtgccgcca gctgccgcac 720
cagcccgaac accattgagg gagctgggag accctcccca cagtgccacc catgcagctg 780
ctccccaggc caccccgctg atggagcccc accttgtctg ctaaataaac atgtgccctc 840
aggccaaaaa aaaaaaaaaa aaa 863
<210> 148
<211> 2029
<212> DNA
<213>Artificial sequence (unknown)
<400> 148
ccgagggtga cactcgggct tgggacaggg cgtgctgccg cgggtcacgt gctgcggagg 60
cttggggagg ggcggcgagg cggggtttat agcccgggcg cccgcgggcc ccacgctttg 120
accgggtcgt ggcagccgga gtcgtcttcg ggacgcgcct gctcttcgcc tttcgctgca 180
gtccgtcgat ttctttctcc aggaagaaaa atggcatccg ttgcagttga tccacaaccg 240
agtgtggtga ctcgggtggt caacctgccc ttggtgagct ccacgtatga cctcatgtcc 300
tcagcctatc tcagtacaaa ggaccagtat ccctacctga agtctgtgtg tgagatggca 360
gagaacggtg tgaagaccat cacctccgtg gccatgacca gtgctctgcc catcatccag 420
aagctagagc cgcaaattgc agttgccaat acctatgcct gtaaggggct agacaggatt 480
gaggagagac tgcctattct gaatcagcca tcaactcaga ttgttgccaa tgccaaaggc 540
gctgtgactg gggcaaaaga tgctgtgacg actactgtga ctggggccaa ggattctgtg 600
gccagcacga tcacaggggt gatggacaag accaaagggg cagtgactgg cagtgtggag 660
aagaccaagt ctgtggtcag tggcagcatt aacacagtct tggggagtcg gatgatgcag 720
ctcgtgagca gtggcgtaga aaatgcactc accaaatcag agctgttggt agaacagtac 780
ctccctctca ctgaggaaga actagaaaaa gaagcaaaaa aagttgaagg atttgatctg 840
gttcagaagc caagttatta tgttagactg ggatccctgt ctaccaagct tcactcccgt 900
gcctaccagc aggctctcag cagggttaaa gaagctaagc aaaaaagcca acagaccatt 960
tctcagctcc attctactgt tcacctgatt gaatttgcca ggaagaatgt gtatagtgcc 1020
aatcagaaaa ttcaggatgc tcaggataag ctctacctct catgggtaga gtggaaaagg 1080
agcattggat atgatgatac tgatgagtcc cactgtgctg agcacattga gtcacgtact 1140
cttgcaattg cccgcaacct gactcagcag ctccagacca cgtgccacac cctcctgtcc 1200
aacatccaag gtgtaccaca gaacatccaa gatcaagcca agcacatggg ggtgatggca 1260
ggcgacatct actcagtgtt ccgcaatgct gcctccttta aagaagtgtc tgacagcctc 1320
ctcacttcta gcaaggggca gctgcagaaa atgaaggaat ctttagatga cgtgatggat 1380
tatcttgtta acaacacgcc cctcaactgg ctggtaggtc ccttttatcc tcagctgact 1440
gagtctcaga atgctcagga ccaaggtgca gagatggaca agagcagcca ggagacccag 1500
cgatctgagc ataaaactca ttaaacctgc ccctatcact agtgcatgct gtggccagac 1560
agatgacacc ttttgttatg ttgaaattaa cttgctaggc aaccctaaat tgggaagcaa 1620
gtagctagta taaaggccct caattgtagt tgtttccagc tgaattaaga gctttaaagt 1680
ttctggcatt agcagatgat ttctgttcac ctggtaagaa aagaatgata ggcttgtcag 1740
agcctatagc cagaactcag aaaaaattca aatgcactta tgttctcatt ctatggccat 1800
tgtgttgcct ctgttactgt ttgtattgaa taaaaacatc ttcatgtggg ctggggtaga 1860
aactggtgtc tgctctggtg tgatctgaaa aggcgtcttc actgctttat ctcatgatgc 1920
ttgcttgtaa aacttgattt tagtttttca tttctcaaat aggaatacta cctttgaatt 1980
caataaaatt cactgcagga tagaccagtt aaaaaaaaaa aaaaaaaaa 2029
<210> 149
<211> 4807
<212> DNA
<213>Artificial sequence (unknown)
<400> 149
aagtgcgcat gtgcgcgagg agtcgctcgg gcacttattg agcgccgact gtctacgggc 60
ggccgggggt gatgggcaga ggcttcagtg tccccttcgc ctccgcagga gaggagaggc 120
agcagcatgg cgagtgtcct gtcccgacgc cttggaaagc ggtccctcct gggagcccgg 180
gtgttgggac ccagtgcctc ggaggggccc tcggctgccc caccctcgga gccactgcta 240
gaaggggccg ctccccagcc tttcaccacc tctgatgaca ccccctgcca ggagcagccc 300
aaggaagtcc ttaaggctcc cagcacctcg ggccttcagc aggtggcctt tcagcctggg 360
cagaaggttt atgtgtggta cgggggtcaa gagtgcacag gactggtgga gcagcacagc 420
tggatggagg gtcaggtgac cgtctggctg ctggagcaga agctgcaggt ctgctgcagg 480
gtggaggagg tgtggctggc agagctgcag ggcccctgtc cccaggcacc acccctggag 540
cccggagccc aggccctggc ctacaggccc gtctccagga acatcgatgt cccaaagagg 600
aagtcggacg cagtggaaat ggatgagatg atggcggcca tggtgctgac gtccctgtcc 660
tgcagccctg ttgtacagag tcctcccggg accgaggcca acttctctgc ttcccgtgcg 720
gcctgcgacc catggaagga gagtggtgac atctcggaca gcggcagcag cactaccagc 780
ggtcactgga gtgggagcag tggtgtctcc accccctcgc ccccccaccc ccaggccagc 840
cccaagtatt tgggggatgc ttttggttct ccccaaactg atcatggctt tgagaccgat 900
cctgaccctt tcctgctgga cgaaccagct ccacgaaaaa gaaagaactc tgtgaaggtg 960
atgtacaagt gcctgtggcc aaactgtggc aaagttctgc gctccattgt gggcatcaaa 1020
cgacacgtca aagccctcca tctgggggac acagtggact ctgatcagtt caagcgggag 1080
gaggatttct actacacaga ggtgcagctg aaggaggaat ctgctgctgc tgctgctgct 1140
gctgccgcag gcaccccagt ccctgggact cccacctccg agccagctcc cacccccagc 1200
atgactggcc tgcctctgtc tgctcttcca ccacctctgc acaaagccca gtcctccggc 1260
ccagaacatc ctggcccgga gtcctccctg ccctcagggg ctctcagcaa gtcagctcct 1320
gggtccttct ggcacattca ggcagatcat gcataccagg ctctgccatc cttccagatc 1380
ccagtctcac cacacatcta caccagtgtc agctgggctg ctgccccctc cgccgcctgc 1440
tctctctctc cggtccggag ccggtcgcta agcttcagcg agccccagca gccagcacct 1500
gcgatgaaat ctcatctgat cgtcacttct ccaccccggg cccagagtgg tgccaggaaa 1560
gcccgagggg aggctaagaa gtgccgcaag gtgtatggca tcgagcaccg ggaccagtgg 1620
tgcacggcct gccggtggaa gaaggcctgc cagcgctttc tggactgagc tgtgctgcag 1680
gttctactct gttcctggcc ctgccggcag ccactgacaa gaggccagtg tgtcaccagc 1740
cctcagcaga aaccgaaaga gaaagaacgg aaacacggag tttgggctct gttggctaag 1800
gtgtaacact taaagcaatt ttctcccatt gtgcgaacat tttatttttt aaaaaaaaga 1860
aacaaaaata tttttccccc taaaatagga gagagccaaa actgaccaag gctattcagc 1920
agtgaaccag tgaccaaaga attaattacc ctccgtttcc cacatcccca ctctctaggg 1980
gattagcttg tgcgtgtcaa aagaaggaac agctcgttct gcttcctgct gagtcggtga 2040
attctttgct ttctaaactc ttccagaaag gactgtgagc aagatgaatt tacttttctt 2100
aaaaaaaaaa aaaaaaaaaa aaaaaaagag tttctggctg atgggtgact cagagtgcag 2160
gactgcctgg ccgtggggca gaggggtttg cccttctcgg agggtacctc ctgttccctg 2220
tctgagcatc ctgcatggaa gtcaaaggaa atccctttct tggtgacgac ttaaatctgg 2280
gttccctcag acattgggtt gcaccccaac aaatattaaa tggcttcttc ttaaagccca 2340
gagaaagagg ttttttaaaa gactgtcgcc aaatagctga gccaaaaggc tgatcagaat 2400
tcactttttg gaatgtggca gttaaacact accttgatca ttctctcctc tttcctcgag 2460
gaactcctgg agggtttgag cgtctggaaa ctctctgctc tgacccgagg aagcaccctc 2520
ctgacgccgc cttcctccgg ttattgaaag gacgcctcag aaatgctttg ttttctttta 2580
cgatgtattc agaagccttt actgattaaa gttttctttt atttgggtgg ccgggagaga 2640
cccagggagg ttctggaggt tcctttctgt ctcctggccc caccagggat ttccccattt 2700
ctgtttgctg cctgaaagca ggatgaggaa ggccaaggag agtccttgca cccgtgagcg 2760
tcaggatgag gaaatgacag gaggaagacg tgggtttggg ttagtggctg ctggcgtttt 2820
ggcccttggt gtttctggag cctccaggga tctaggggag cctgggctgc gtgcatgtcg 2880
ataagcagag ctgttcttgg ggagaaggag ggaggtctcg ggagtgtagc accatgccaa 2940
ccagccctgc gcgaagacag agtgagccac gcccggatgg cagggcatgt ttctgttttg 3000
gtgtctcact ttcctcccag cgtgacttat ttggggattc ctcagggcct actggaatgt 3060
gactgcccac tgcccagctg cctcgggtac aagtcctggc cctatgtccc agctgtcagg 3120
ggctcaggga atcctaccca gccacctgtc ctgggatgga gtgtcagcat ccaccccttg 3180
gttgtcatcg aggccgccct cccagtcctg ggtgaagata tttgggccac cagggctccc 3240
ttggcccctt cacgtaggaa atagacacgt gctttttaat gcaggacact ttgagtgtta 3300
caaaatctgt agacctggca gtagggtcat gatgttggga agggtgtagt gccctaggtt 3360
ggtgacagaa gggacagaca cttgtgcaca ggtgtctttg gtgatggggt tttttttttt 3420
ataacttagt aaaaaaaaaa aaatgtatgt ggaattctgt ctcttggtaa agctcaaagc 3480
caggctagcc tgaggtggcg cagggctctc cttcctgtcc cttcgatctc cttgagaatt 3540
aagagctggc agctgctgat ggtgtttccc aacccccctc acttcccaag acaaccccca 3600
gcttcaggtc ctcatgggga ggggagggca cgttcttgac acatgggaac ttcgctcagg 3660
agggcctccc cttcccctct ccctcagagt tttcactgcc gtctcgtctt tagaaagctg 3720
tttgaattcc ccccgccccc agtttggacc gtgtagatat aactggatat acggattttt 3780
ctctttgtgc aggcttctta tgccgttggt atacagggca ggaaagagag gaataaaggg 3840
agagagcagt gtggaaacca cggtggtttt gctttgttct tactaggttt tggtgccacc 3900
ttccctgcct gcgcttgtgc cccctctcct ccttggcact ggcggcctcc ttgcctccct 3960
tccacccgtg ctgccatccc gtgcctgtcg tgttggttct tcacacgtgc tctgttctcg 4020
gggttgttcc attcatgcct tcttggaggg tgagggtggc ttgggaaccg acccagtgat 4080
catgcctact ttcttctttg tatctccctc cttcccagcc cacccgggca gcagactctg 4140
atggaaggaa ggtgccgtag gtgggctttt agaaactaac gggactggtt ttcaaagcag 4200
ttatcttggg aaactgttta ttccagcgat gtgacttttt tcagaatatt tcttggaatc 4260
atattcagag tctggggctg tgtgttgagc agccttaagg atgctagaca ctcatttagt 4320
gcccagggag tccagcgaat gacgtctgtg gccaagcgag gtctcaggtg caaagcaaaa 4380
ggaccattta aagtaaaata gcttggattc aatcatgtga cttttaaatt ggctcagaaa 4440
gcaattttgt aatttcagag agtgttttga gccatggcca cgttgtcatt gtgagtctat 4500
agcttgactc cttggagaac aatattcatt tggttgtgga gactgatttg ctgggagaaa 4560
tctgtcctgt tactttctgg tcatcccagg ttctgacttt taccaggggc aaaaaaaaaa 4620
aaagcaagag ggagataaat cccatctgtg agtttgtctt attggcgcct ttttcctcag 4680
ctgtcttcca agtattattt ttactgttaa aaaatttttt aaaaatgtga aatgtaatgt 4740
ttttacagca acaatatgaa atatatttta taaggaataa aatggtacct tgtctgattt 4800
aaaaaaa 4807
<210> 150
<211> 2080
<212> DNA
<213>Artificial sequence (unknown)
<400> 150
gcgggtcccc agaagcctac aggtgagtat cggttctccc cttcccggct ttcggtccgg 60
aggaggcggg agcagcttcc ctgttctgat cctatcgcgg gcggcgcagg gccggcttgg 120
ccttccgtgg gacggggagg ggggcgggat gtgtcaccca aataccagtg gggacggtcg 180
gtggtggaac cagccgggca ggtcgggtag agtataagag ccggagggag cggccgggcg 240
gcagacgcct gcagaccatc ccagacgccg gagcccgagc cccgacgagt ccccgcgcct 300
catccgcccg cgtccggtcc gcgttcctcc gccccaccat ggctcggggc cccggcctcg 360
cgccgccacc gctgcggctg ccgctgctgc tgctggtgct ggcggcggtg accggccaca 420
cggccgcgca ggacaactgc acgtgtccca ccaacaagat gaccgtgtgc agccccgacg 480
gccccggcgg ccgctgccag tgccgcgcgc tgggctcggg catggcggtc gactgctcca 540
cgctgacctc caagtgtctg ctgctcaagg cgcgcatgag cgcccccaag aacgcccgca 600
cgctggtgcg gccgagtgag cacgcgctcg tggacaacga tggcctctac gaccccgact 660
gcgaccccga gggccgcttc aaggcgcgcc agtgcaacca gacgtcggtg tgctggtgcg 720
tgaactcggt gggcgtgcgc cgcacggaca agggcgacct gagcctacgc tgcgatgagc 780
tggtgcgcac ccaccacatc ctcattgacc tgcgccaccg ccccaccgcc ggcgccttca 840
accactcaga cctggacgcc gagctgaggc ggctcttccg cgagcgctat cggctgcacc 900
ccaagttcgt ggcggccgtg cactacgagc agcccaccat ccagatcgag ctgcggcaga 960
acacgtctca gaaggccgcc ggtgacgtgg atatcggcga tgccgcctac tacttcgaga 1020
gggacatcaa gggcgagtct ctattccagg gccgcggcgg cctggacttg cgcgtgcgcg 1080
gagaacccct gcaggtggag cgcacgctca tctattacct ggacgagatt cccccgaagt 1140
tctccatgaa gcgcctcacc gccggcctca tcgccgtcat cgtggtggtc gtggtggccc 1200
tcgtcgccgg catggccgtc ctggtgatca ccaaccggag aaagtcgggg aagtacaaga 1260
aggtggagat caaggaactg ggggagttga gaaaggaacc gagcttgtag gtacccggcg 1320
gggcagggga tggggtgggg taccggattt cggtatcgtc ccagacccaa gtgagtcacg 1380
cttcctgatt cctcggcgca aaggagacgt ttatcctttc aaattcctgc cttccccctc 1440
ccttttgcgc acacaccagg tttaatagat cctggcctca gggtctcctt tctttctcac 1500
ttctgtcttg aaggaagcat ttctaaaatg tatccccttt cggtccaaca acaggaaacc 1560
tgactggggc agtgaaggaa gggatggcat agcgttatgt gtaaaaaaca agtatctgta 1620
tgacaacccg ggatcgtttg caagtaactg aatccattgc gacattgtga aggcttaaat 1680
gagtttagat gggaaatagc gttgttatcg ccttgggttt aaattatttg atgagttcca 1740
cttgtatcat ggcctacccg aggagaagag gagtttgtta actgggccta tgtagtagcc 1800
tcatttacca tcgtttgtat tactgaccac atatgcttgt cactgggaaa gaagcctgtt 1860
tcagctgcct gaacgcagtt tggatgtctt tgaggacaga cattgcccgg aaactcagtc 1920
tatttattct tcagcttgcc cttactgcca ctgatattgg taatgttctt ttttgtaaaa 1980
tgtttgtaca tatgttgtct ttgataatgt tgctgtaatt ttttaaaata aaacacgaat 2040
ttaataaaat atgggaaagg cacaaaccag aaaaaaaaaa 2080
<210> 151
<211> 1275
<212> DNA
<213>Artificial sequence (unknown)
<400> 151
gtctccgcct gcaggtgcag acatctggag gagagagtcg gagagcagaa accacttggc 60
tcccagacaa ttcccctaca ggctttgggc ctggaattga ggagaaagtg agctaagttg 120
gggtggggtg agtccaaaga agcacgggct gggccaagct aagctgctct gggctgggct 180
gatccctccc cactcagggg cgggacccca ggaggaggga gaggacagag ccactgcaga 240
ggaccagact gggaaaacaa cgatatggca ggagccagtc ttggggcccg cttctaccgg 300
cagatcaaaa gacatccggg gatcatcccg atgatcggct taatctgcct gggcatgggc 360
agcgctgcgc tttacttgct gcgactcgcc cttcgcagcc ccgacgtctg ctgggacaga 420
aagaacaacc cggagccctg gaaccgcctg agccccaatg accaatacaa gttccttgca 480
gtttccactg actataagaa gctgaagaag gaccggccag acttctaagc caggctgggc 540
tgccagtgcc atgcaagcca cagccagcca gcccatccac ttcttccact cctccccgca 600
ggccccaagg catcactccg gccaccctgt cccgctactg cttacacagg ccgggttccc 660
acgcagaggg gaggctgctc cacccctact ctcctccctt gctcccagca gcggaagcgc 720
ctctgaccct tggcttgagt cccacgtggg ggaggaggag gcaggcagca ccagcagggg 780
tccaccaaga gcccagacca gcccctctgc cctcctaccc gggcctcgaa gggtgtggca 840
caggctacgt gttgagcgtg gcctacgtga gccaacaaga agcaggggcc tctgagtgcc 900
aagcgacgtg gcgggctcca cgttagccca ggctctgaga gccagcccag gggcggcgct 960
gctcagcttg ggctggtcca gggcctgccc aggctggggc acctttgcct cctgaggcgc 1020
agcgcactcc tcccctgccc aagcctactg cctcccgctg ccgccagtac cccctccagc 1080
cccacacctg ggcctccccc tgccactccc ctcccttgct cccctctgtc cccagggatc 1140
aaacagaagc agccgtgggc aaaatacaat ttcatttaac aaattgaaaa aaaaaaaaaa 1200
aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1260
aaaaaaaaaa aaaaa 1275
<210> 152
<211> 1579
<212> DNA
<213>Artificial sequence (unknown)
<400> 152
gaggaggtgc ttgccagaca ctgggtcatg gcagtggtcg gtgaagctgc agttgcctag 60
ggcagggatg gagagagagt ctgggcatga ggagagggtc tcgggatgtt tggctggact 120
agattttaca gaaagcctta tccaggcttt taaaattact ctttccagac ttcatctgag 180
actccttctt cagccaacat tccttagccc tgaatacatt tcctatcctc atctttccct 240
tctttttttt cctttctttt acatgtttaa atttaaacca ttcttcgtga ccccttttct 300
tgggagattc atggcaagaa cgagaagaat gatggtgctt gttaggggat gtcctgtctc 360
tctgaacttt ggggtcctat gcattaaata attttcctga cgagctcaag tgctccctct 420
ggtctacaat ccctggcggc tggccttcat cccttgggca agcattgcat acagctcatg 480
gccctccctc taccataccc tccacccccg ttcgcctaag ctcccttctc cgggaatttc 540
atcatttcct agaacagcca gaacatttgt ggtctatttc tctgttagtg tttaaccaac 600
catctgttct aaaagaaggg ctgaactgat ggaaggaatg ctgttagcct gagactcagg 660
aagacaactt ctgcagggtc actccctggc ttctggagga aagagaagga gggcagtgct 720
ccagtggtac agaagtgaga cataatggaa tcaggcttca cctccaagga cacctatcta 780
agccatttta accctcggga ttacctagaa aaatattaca agtttggttc taggcactct 840
gcagaaagcc agattcttaa gcaccttctg aaaaatcttt tcaagatatt ctgcctagac 900
ggtgtgaagg gagacctgct gattgacatc ggctctggcc ccactatcta tcagctcctc 960
tctgcttgtg aatcctttaa ggagatcgtc gtcactgact actcagacca gaacctgcag 1020
gagctggaga agtggctgaa gaaagagcca gaggcctttg actggtcccc agtggtgacc 1080
tatgtgtgtg atcttgaagg gaacagagtc aagggtccag agaaggagga gaagttgaga 1140
caggcggtca agcaggtgct gaagtgtgat gtgactcaga gccagccact gggggccgtc 1200
cccttacccc cggctgactg cgtgctcagc acactgtgtc tggatgccgc ctgcccagac 1260
ctccccacct actgcagggc gctcaggaac ctcggcagcc tactgaagcc agggggcttc 1320
ctggtgatca tggatgcgct caagagcagc tactacatga ttggtgagca gaagttctcc 1380
agcctccccc tgggccggga ggcagtagag gctgctgtga aagaggctgg ctacacaatc 1440
gaatggtttg aggtgatctc gcaaagttat tcttccacca tggccaacaa cgaaggactt 1500
ttctccctgg tggcgaggaa gctgagcaga cccctgtgat gcctgtgacc tcaattaaag 1560
caattccttt gacctgtca 1579
<210> 153
<211> 1318
<212> DNA
<213>Artificial sequence (unknown)
<400> 153
ggggcgtgct cgcggctata aggggcggag gctgggcggc gttgctctgc gctctgcggc 60
tgacggcgct tttgtctccg ggtccagagg cctttcagaa ggagaaggca gctctgtttc 120
tctgcagagg agtagggtcc tttcagccat gaagcatgtg ttgaacctct acctgttagg 180
tgtggtactg accctactct ccatcttcgt tagagtgatg gagtccctag agggcttact 240
agagagccca tcgcctggga cctcctggac caccagaagc caactagcca acacagagcc 300
caccaagggc cttccagacc atccatccag aagcatgtga taagacctcc ttccatactg 360
gccatatttt ggaacactga cctagacatg tccagatggg agtcccattc ctagcagaca 420
agctgagcac cgttgtaacc agagaactat tactaggcct tgaagaacct gtctaactgg 480
atgctcattg cctgggcaag gcctgtttag gccggttgcg gtggctcatg cctgtaatcc 540
tagcactttg ggaggctgag gtgggtggat cacctgaggt caggagttcg agaccagcct 600
cgccaacatg gcgaaacccc atctctacta aaaatacaaa agttagctgg gtgtggtggc 660
agaggcctgt aatcccagct ccttgggagg ctgaggcggg agaattgctt gaacccgggg 720
acggaggttg cagtgagccg agatcgcact gctgtaccca gcctgggcca cagtgcaaga 780
ctccatctca aaaaaaaaag aaaagaaaaa gcctgtttaa tgcacaggtg tgagtggatt 840
gcttatggct atgagatagg ttgatctcgc ccttaccccg gggtctggtg tatgctgtgc 900
tttcctcagc agtatggctc tgacatctct tagatgtccc aacttcagct gttgggagat 960
ggtgatattt tcaaccctac ttcctaaaca tctgtctggg gttcctttag tcttgaatgt 1020
cttatgctca attatttggt gttgagcctc tcttccacaa gagctcctcc atgtttggat 1080
agcagttgaa gaggttgtgt gggtgggctg ttgggagtga ggatggagtg ttcagtgccc 1140
atttctcatt ttacatttta aagtcgttcc tccaacatag tgtgtattgg tctgaagggg 1200
gtggtgggat gccaaagcct gctcaagtta tggacattgt ggccaccatg tggcttaaat 1260
gattttttct aactaataaa gtggaatata tatttctaaa aaaaaaaaaa aaaaaaaa 1318
<210> 154
<211> 2427
<212> DNA
<213>Artificial sequence (unknown)
<400> 154
aacaacaacc tcacagcttg gacaaggcaa acattatgcc aggaggaaaa aatattccac 60
ccccaagaaa acaatatcaa aaaacagaac tagagactaa ttggaggaga gattgccagc 120
ctggggcaaa tgtgtatata taagtatgag gcacatcatg accagactaa ctctaccttt 180
ctggcttcag gtgctatcta gacctgaagt agcgggaaga gcagaaagga tggggcagcc 240
atctctgact tggatgctga tggtggtggt ggcctcttgg ttcatcacaa ctgcagccac 300
tgacacctca gaagcaagat ggtgctctga atgtcacagc aatgccacct gcacggagga 360
tgaggccgtt acgacgtgca cctgtcagga gggcttcacc ggcgatggcc tgacctgcgt 420
ggacctggat gagtgcgcca ttcctggagc tcacaactgc tccgccaaca gcagctgcgt 480
aaacacgcca ggctccttct cctgcgtctg ccccgaaggc ttccgcctgt cgcccggtct 540
cggctgcaca gacgtggatg agtgcgctga gcctgggctt agccactgcc acgccctggc 600
cacatgtgtc aatgtggtgg gcagctactt gtgcgtatgc cccgcgggct accgggggga 660
tggatggcac tgtgagtgct ccccgggctc ctgcgggccg gggttggact gcgtgcccga 720
gggcgacgcg ctcgtgtgcg cggatccgtg ccaggcgcac cgcaccctgg acgagtactg 780
gcgcagcacc gagtacgggg agggctacgc ctgcgacacg gacctgcgcg gctggtaccg 840
cttcgtgggc cagggcggtg cgcgcatggc cgagacctgc gtgccagtcc tgcgctgcaa 900
cacggccgcc cccatgtggc tcaatggcac gcatccgtcc agcgacgagg gcatcgtgag 960
ccgcaaggcc tgcgcgcact ggagcggcca ctgctgcctg tgggatgcgt ccgtccaggt 1020
gaaggcctgt gccggcggct actacgtcta caacctgaca gcgccccccg agtgtcacct 1080
ggcgtactgc acagacccca gctccgtgga ggggacgtgt gaggagtgca gtatagacga 1140
ggactgcaaa tcgaataatg gcagatggca ctgccagtgc aaacaggact tcaacatcac 1200
tgatatctcc ctcctggagc acaggctgga atgtggggcc aatgacatga aggtgtcgct 1260
gggcaagtgc cagctgaaga gtctgggctt cgacaaggtc ttcatgtacc tgagtgacag 1320
ccggtgctcg ggcttcaatg acagagacaa ccgggactgg gtgtctgtag tgaccccagc 1380
ccgggatggc ccctgtggga cagtgttgac gaggaatgaa acccatgcca cttacagcaa 1440
caccctctac ctggcagatg agatcatcat ccgtgacctc aacatcaaaa tcaactttgc 1500
atgctcctac cccctggaca tgaaagtcag cctgaagacc gccctacagc caatggtcag 1560
tgctctaaac atcagagtgg gcgggaccgg catgttcacc gtgcggatgg cgctcttcca 1620
gaccccttcc tacacgcagc cctaccaagg ctcctccgtg acactgtcca ctgaggcttt 1680
tctctacgtg ggcaccatgt tggatggggg cgacctgtcc cgatttgcac tgctcatgac 1740
caactgctat gccacaccca gtagcaatgc cacggacccc ctgaagtact tcatcatcca 1800
ggacagatgc ccacacacta gagactcaac tatccaagtg gtggagaatg gggagtcctc 1860
ccagggccga ttttccgtcc agatgttccg gtttgctgga aactatgacc tagtctacct 1920
gcactgtgaa gtctatctct gtgacaccat gaatgaaaag tgcaagccta cctgctctgg 1980
gaccagattc cgaagtggga gtgtcataga tcaatcccgt gtcctgaact tgggtcccat 2040
cacacggaaa ggtgtccagg ccacagtctc aagggctttt agcagcttgg ggctcctgaa 2100
agtctggctg cctctgcttc tctcggccac cttgaccctg acttttcagt gactgacagc 2160
ggaaagccct gtgctccatg gctgccatct cacctcctgc tgggcagggg gcatgatgcg 2220
ggccagtgct ccagccacag aaaagaaagt tcatgctttg ttcagcctgc cttcttttct 2280
cccttttaat cctggctgtc gagaaacagc ctgtgtcttt aaatgctgct ttttctcaaa 2340
atgggacttg tgacggtgta cctgaggccc ccatctcctt aaagagtgtg gcaaaataat 2400
gatttttaaa tctcaaaaaa aaaaaaa 2427
<210> 155
<211> 4717
<212> DNA
<213>Artificial sequence (unknown)
<400> 155
tacatttcct cagaagaagg ctccttggtg ctttgaagaa catcctgaag attatatcgg 60
agacaatata tcaagaatct atttattgaa tcatctagaa caaaagccag gagctcccta 120
atggaagcac attagtgttt attttgatga agaaatatat agatttttta aaacaaccac 180
aaagtagata gctcagtaaa aaatcaattt tggaagatgt cactgaacaa ctcttccaat 240
gtatttctgg attcagtgcc cagtaatacc aatcgctttc aagttagtgt cataaatgag 300
aaccatgaga gcagtgcagc tgcagatgac aatactgacc caccacatta tgaagaaacc 360
tcttttgggg atgaagctca gaaaagactc agaatcagct ttaggcctgg gaatcaggag 420
tgctatgaca atttcctcca aagtggagaa actgctaaaa cagatgccag ttttcacgct 480
tatgattctc acacaaacac atactatcta caaacttttg gccacaacac catggatgcc 540
gttcccaaga tagagtacta tcgtaacacc ggcagcatca gtgggcccaa ggtcaaccga 600
cccagcctgc ttgagattca cgagcaactc gcaaagaatg tggcagtcac cccaagttca 660
gctgacagag ttgctaacgg tgatgggata cctggagatg aacaagctga aaataaggaa 720
gatgatcaag ctggtgttgt gaagtttgga tgggtgaaag gtgtgctggt aagatgcatg 780
ctgaacatct ggggagtcat gctcttcatt cgcctctcct ggattgttgg agaagctgga 840
attggtcttg gagttctcat aattcttctt tccaccatgg taacttctat tactgggttg 900
tcaacttctg cgatagcaac taacgggttt gttcgtggag gtggggccta ctatcttatt 960
tccagaagtt tagggcccga gttcggtggg tcaataggcc tgatctttgc ttttgctaat 1020
gcagtggctg ttgctatgta tgtggtggga tttgctgaga ctgtagtaga tcttcttaag 1080
gagagtgatt cgatgatggt ggatccaacc aatgacatcc ggattatagg ctccatcaca 1140
gtggtgattc ttctaggaat ttcagtagct ggaatggaat gggaggcaaa ggcccaagtc 1200
attcttctgg tcattcttct aattgctatt gcaaacttct tcattggaac tgtcattcca 1260
tccaacaatg agaaaaagtc cagaggtttc tttaattacc aagcatcaat atttgcagaa 1320
aactttgggc cacgcttcac aaagggtgaa ggcttcttct ctgtctttgc catttttttc 1380
ccagcagcta ctgggattct tgctggtgcc aatatctcag gagatttgga ggatccccaa 1440
gatgccatcc ccagaggaac catgctggcc attttcatca ccactgttgc ctacttaggg 1500
gttgcaattt gtgtaggggc ctgtgtggtc cgagatgcca ccgggaacat gaatgacacc 1560
atcatttctg ggatgaactg caatggttca gcagcatgtg ggttgggcta tgacttctca 1620
agatgtcgac atgaaccatg tcagtacggg ctgatgaaca atttccaggt catgagcatg 1680
gtatcagggt tcggccccct catcactgcg ggaatctttt ctgcaacact ctcctccgcc 1740
ctggcctccc ttgtcagcgc acccaaagtg ttccaggctc tgtgcaagga caacatctac 1800
aaagccctgc agttttttgc aaagggatat gggaaaaaca atgaacccct gagaggatat 1860
attctcactt ttcttatagc catggcattt attcttattg cggaactgaa caccattgct 1920
cccatcatct ccaacttttt cctggcctca tatgcactta ttaatttctc ctgcttccat 1980
gcctcttatg ccaaatctcc aggatggaga cctgcgtatg gaatttacaa catgtgggta 2040
tctctttttg gagctgtttt gtgctgtgca gtcatgtttg tcatcaactg gtgggcagct 2100
gtcatcacct atgtcattga attcttcctt tacgtctatg tgacttgtaa gaagccagat 2160
gtgaactggg gctcctccac acaggctctt tcctacgtga gtgctttaga caatgctctg 2220
gaattaacca cagtggaaga ccacgtaaaa aacttcaggc cccagtgcat tgtcttaaca 2280
gggggaccca tgacaagacc tgctctcctg gacataactc acgcctttac caagaacagt 2340
ggcctttgca tctgctgtga agtctttgtg ggaccgcgca aactgtgtgt taaggagatg 2400
aacagtggca tggcgaaaaa acaggcctgg cttataaaga acaaaatcaa ggctttttat 2460
gctgcagtgg cggcagactg tttcagggat ggtgtccgaa gtcttcttca ggcctcaggc 2520
ttaggaagaa tgaaaccaaa cactctggtg attggatata agaaaaactg gaggaaagct 2580
cccttgacag agattgagaa ctacgtggga atcatacatg atgcatttga ttttgagatt 2640
ggcgtggtta tagtcagaat cagccaagga tttgacatct ctcaggttct tcaggtgcaa 2700
gaggaattag agagattaga acaggagaga ctagcattgg aagcgactat caaagataat 2760
gagtgtgaag aggaaagtgg aggcatccga ggcttgttta aaaaagctgg caagttgaac 2820
attactaaga caacgcctaa aaaagatggc agcattaaca caagccagtc gatgcatgtg 2880
ggagagttca accagaaact ggtggaagcc agcactcaat ttaaaaagaa acaagaaaaa 2940
ggcacaattg atgtttggtg gttgtttgat gatggagggt taacacttct tatcccctat 3000
atcttaactc tcagaaaaaa atggaaagac tgtaaattaa gaatctatgt gggagggaag 3060
atcaaccgca ttgaagaaga aaaaattgta atggcttccc ttctgagcaa atttaggata 3120
aaatttgcag acatccatat catcggtgac atcaacatta ggccaaacaa agagagctgg 3180
aaagtctttg aagagatgat tgaaccatat cgtctccatg aaagctgcaa agatttaaca 3240
actgctgaga aattaaaaag agaaactccg tggaaaatta cagatgcaga actggaagca 3300
gtcaaggaaa agagttaccg ccaagttcga ctgaatgaac tcttacagga gcactccaga 3360
gctgctaatc tcattgtcct gagccttccc gtggcaagaa agggatccat atcggatttg 3420
ttgtatatgg cttggttgga aatcctcaca aagaacctcc cacctgtctt actagttaga 3480
ggaaatcaca aaaatgtctt gacattttac tcttaaaaca tgaaagattg gaatacattt 3540
taacttaatg taatgcataa ttaagaaaca tgttccagta ctttatgttg taaatctgat 3600
ctatggatat gcaaacctct ggagaggatc ctaccagatt ctacatacat tgcataattt 3660
ttatcagtta atgcgagctt ttttttctct tctcagctta aggggttgtc aaagccaatg 3720
ttatccctag aaaaacattt ttgtcactgc tgttgataaa caagaaaatc aaggaaactc 3780
atgttggctt atgctcatga aaaccaccaa tgtgattgta aacttctcca gacaaactta 3840
accttttgtt tcttaatttt ttgttttgag tgtttgcttc tcagccctgg tataggtctc 3900
agccccacag caggatctca ataaatgctt attgacaggc tggcatagta accacaggtg 3960
gttatcaaag gaaaagacca ataggctggg gaacataatt atgcttggcc ccctcagagg 4020
cttatacctc caaagcagat ttaaaaatca gtaactcaaa actttaagaa gtagttgagt 4080
ctacaaaata ttcaaagcag ttacctaaat aaggttattt aatgtaacag attatatact 4140
taaagtgatc tgagcaatca ttgataacat atggcttaaa tttgctgctg cctgaaaagt 4200
atattaacta gattagaaga caccatatac tccaataaaa tgaaatatat tctattctca 4260
atatataaac tttaattgta ctccctatca aatattttga aatttccatc acggcattac 4320
tttgcatatt tttttctaat taaatggtta gtacagatga aatctttata gatgactact 4380
tgaaaactaa gtgctacaaa ttttcaaacc attattaaga aatatatcct gaatcatata 4440
tttagttact ttctatagtg attgtatgga tttaaaagaa taattaaaat gtgaagttga 4500
aaaacttgta aaatttggaa tatacagata ctgatttttt tcatttttgt tagtatacct 4560
ataatacata atcacattga caaaccaatg aaaatattga ttttctgatg aatggcttga 4620
tttttctcct tgacatgttt tgactgttca ttctaactga aaacatatat gggaaaatat 4680
gaacctgaaa taaaagcact caaattcaaa aaaaaaa 4717
<210> 156
<211> 2551
<212> DNA
<213>Artificial sequence (unknown)
<400> 156
gtagggagag aactctggag gaacgctgag ctgagcagca ccgaggacag cgcccggcag 60
cgcccgcgcc caggtctccc tccgcagccc tgactcgcgc acacgctgag cttttgctca 120
ctccccctcg cgcggacaca gacacacgca tattcacaca cccagacaca caccccgctg 180
tacaatggca gaatcccacc tgcagtcatc cctcatcaca gcctcacagt ttttcgagat 240
ctggctccat ttcgacgctg acggaagtgg ttacctggaa ggaaaggagc tgcagaactt 300
gatccaggag ctccagcagg cgcgaaagaa ggctggattg gagttatcac ctgaaatgaa 360
aacttttgtg gatcagtatg ggcaaagaga tgatggaaaa ataggaattg tagagttggc 420
tcacgtatta cccacagaag agaatttcct gctgctcttc cgatgccagc agctgaagtc 480
ctgtgaggaa ttcatgaaga catggagaaa atatgatact gaccacagtg gcttcataga 540
aactgaggag cttaagaact ttctaaagga cctgctagaa aaagcaaaca agactgttga 600
tgacacaaaa ttagccgagt atacagacct aatgctgaaa ctatttgatt caaataatga 660
tgggaagctg gaattaactg agatggccag gttactacca gtgcaggaga attttcttct 720
taaattccag ggaatcaaaa tgtgtgggaa agagttcaat aaggcttttg agctgtatga 780
tcaggacggc aatggataca tagatgaaaa tgaactggat gctttactga aggatctgtg 840
cgagaagaat aaacaggatc tggatattaa taatattaca acatacaaga agaacataat 900
ggctttgtcg gatggaggga agctgtaccg aacggatctt gctcttattc tctgtgctgg 960
ggataactag agttggtggc cgcaaccact tgctagtgat acactgtatc taaaaaataa 1020
ctgtgcacta taagggagta ggctgtattt tcttttatat ctgtaaattt aactgcatat 1080
agataattat ccaggatgtg tggctcattc ttttcagctt gtttctatac tgtttgtaat 1140
atacagtttt tgtaaccata tgattgaaaa gaagaaagtc tatgcttagg ccagtcagta 1200
cacccaattt taaaaaataa catattcttg ctttcacaaa tatagttgaa caagatttcc 1260
ctaaaaattc caccaggatt aatctctaaa attctagtct ctgatttgca aatgcacatt 1320
tgtcactgaa taatggaatt atgtataaca agccaaacat tcttatttta gacaaccata 1380
gaactgtccc acaaaatatt tctaagctta tttctaacta ttaggaggaa tgtgcttttc 1440
catctaaaat actcaccaaa atatagttaa ttgtggcttt atgaagttaa cagtctcatt 1500
acagatttag tttaccaatc aacagcatgt ctactgcttg gatccataca aaactatcgg 1560
ttcaagttga tgtgacaagg gaagggagca ccagatgaca cataaatctg tctgattcta 1620
tgcctgtatt tccaacaaac ttactgtcag agaatatgac ctaaatccat tttctaaact 1680
gttttcatgt gttgcaaatt attctagtca actgctgttt tatgtcatac tctgtgtaat 1740
ctctgattaa atttaatata ctgcatatcc tggtgtctag tttgcatact tcctggattt 1800
tctttctatg tagaactgtt catttccacc aagggtatct gctgcctctg aaaatatttt 1860
tttctagcta taacaactct attttttact acataattaa attttaatgt aaaattcata 1920
gcatcctgat tattgaatgt tatatcatca atacttttgt gtattctgtg gattctatat 1980
ttcatattga gatcagcatt caaaatagtt ctatttctat ctgcaaatag tttcaaatga 2040
gtttaaaaaa ataacatctg aaaagaaatg ctaatgtaat catttatctt atctagcaag 2100
aagattctaa aacattcttt aacatacatc taagtcagtt tcacatattt gtagctagaa 2160
tatcctatac tggttatagt tgatatgtaa cagttggtga ttttagattt ctttgattgt 2220
gaaacaggga gctatgagag atgtgtccat gtgaaattta cagttactgc ctaggagtta 2280
atgatcgttc tgggtcagct tgaatgtccc cattctataa attcaacact tattttctga 2340
attcataaaa ataaccaaaa aatgtgagct ataatgtttc cctcaagaac aaacagaaac 2400
gagatttgcc aaaaactaaa attcaacaaa tgatgttgag tgggagattg gctttgcctt 2460
tagcgtgtaa atggaagcac tgccattaga ctgaatttaa ctactaagaa taaataaaga 2520
agaaaataac cttaaaaaaa aaaaaaaaaa a 2551
<210> 157
<211> 5964
<212> DNA
<213>Artificial sequence (unknown)
<400> 157
attgaactga gaacatttgc tgtgtttcct gatttataga tatgtttcta agaaacatat 60
ctataacttc caaacagtcc cagctggctg tagctaaggc tgtgtaattg ataagatgca 120
tctggtttca aggcacagat taagtacaag gtcaggctct tgctgtcgtt ggagaatccg 180
gttggggtag gagctaaatc tcaggaccac ttgctctata tatgagtgcc aagataatct 240
agagcaggga gaggcagaga ggcaggcagc ctgctgggct cttcctgctg ttgaaaactt 300
acccggccct tacagaggaa atcttcctcc tctcttctgc cctgaatgtt ttcccaaaca 360
tgaaggtgat aagcttattc attttggtgg gatttatagg agagttccaa agtttttcaa 420
gtgcctcctc tccagtcaac tgccagtggg acttctatgc cccttggtca gaatgcaatg 480
gctgtaccaa gactcagact cgcaggcggt cagttgctgt gtatgggcag tatggaggcc 540
agccttgtgt tggaaatgct tttgaaacac agtcctgtga acctacaaga ggatgtccaa 600
cagaggaggg atgtggagag cgtttcaggt gcttttcagg tcagtgcatc agcaaatcat 660
tggtttgcaa tggggattct gactgtgatg aagacagtgc tgatgaagac agatgtgagg 720
actcagaaag gagaccttcc tgtgatatcg ataaacctcc tcctaacata gaacttactg 780
gaaatggtta caatgaactc actggccagt ttaggaacag agtcatcaat accaaaagtt 840
ttggtggtca atgtagaaag gtgtttagtg gggatggaaa agatttctac aggctgagtg 900
gaaatgtcct gtcctataca ttccaggtga aaataaataa tgattttaat tatgaatttt 960
acaatagtac ttggtcttat gtaaaacata cgtcgacaga acacacatca tctagtcgga 1020
agcgctcctt ttttagatct tcatcatctt cttcacgcag ttatacttca cataccaatg 1080
aaatccataa aggaaagagt taccaactgc tggttgttga gaacactgtt gaagtggctc 1140
agttcattaa taacaatcca gaatttttac aacttgctga gccattctgg aaggagcttt 1200
cccacctccc ctctctgtat gactacagtg cctaccgaag attaatcgac cagtacggga 1260
cacattatct gcaatctggg tcgttaggag gagaatacag agttctattt tatgtggact 1320
cagaaaaatt aaaacaaaat gattttaatt cagtcgaaga aaagaaatgt aaatcctcag 1380
gttggcattt tgtcgttaaa ttttcaagtc atggatgcaa ggaactggaa aacgctttaa 1440
aagctgcttc aggaacccag aacaatgtat tgcgaggaga accgttcatc agagggggag 1500
gtgcaggctt catatctggc cttagttacc tagagctgga caatcctgct ggaaacaaaa 1560
ggcgatattc tgcctgggca gaatctgtga ctaatcttcc tcaagtcata aaacaaaagc 1620
tgacaccttt atatgagctg gtaaaggaag taccttgtgc ctctgtgaaa aaactatacc 1680
tgaaatgggc tcttgaagag tatctggatg aatttgaccc ctgtcattgc cggccttgtc 1740
aaaatggtgg tttggctact gttgagggga cccattgtct gtgccattgc aaaccgtaca 1800
catttggtgc ggcgtgtgag caaggagtcc tcgtagggaa tcaagcagga ggggttgatg 1860
gaggttggag ttgctggtcc tcttggagcc cctgtgtcca agggaagaaa acaagaagcc 1920
gtgaatgcaa taacccacct cccagtgggg gtgggagatc ctgcgttgga gaaacgacag 1980
aaagcacaca atgcgaagat gaggagctgg agcacttgag gttgcttgaa ccacattgct 2040
ttcctttgtc tttggttcca acagaattct gtccatcacc tcctgccttg aaagatggat 2100
ttgttcaaga tgaaggtaca atgtttcctg tggggaaaaa tgtagtgtac acttgcaatg 2160
aaggatactc tcttattgga aacccagtgg ccagatgtgg agaagattta cggtggcttg 2220
ttggggaaat gcattgtcag aaaattgcct gtgttctacc tgtactgatg gatggcatac 2280
agagtcaccc ccaaaaacct ttctacacag ttggtgagaa ggtgactgtt tcctgttcag 2340
gtggcatgtc cttagaaggt ccttcagcat ttctctgtgg ctccagcctt aagtggagtc 2400
ctgagatgaa gaatgcccgc tgtgtacaaa aagaaaatcc gttaacacag gcagtgccta 2460
aatgtcagcg ctgggagaaa ctgcagaatt caagatgtgt ttgtaaaatg ccctacgaat 2520
gtggaccttc cttggatgta tgtgctcaag atgagagaag caaaaggata ctgcctctga 2580
cagtttgcaa gatgcatgtt ctccactgtc agggtagaaa ttacaccctt actggtaggg 2640
acagctgtac tctgcctgcc tcagctgaga aagcttgtgg tgcctgccca ctgtggggaa 2700
aatgtgatgc tgagagcagc aaatgtgtct gccgagaagc atcggagtgc gaggaagaag 2760
ggtttagcat ttgtgtggaa gtgaacggca aggagcagac gatgtctgag tgtgaggcgg 2820
gcgctctgag atgcagaggg cagagcatct ctgtcaccag cataaggcct tgtgctgcgg 2880
aaacccagta ggctcctgga ggccctggtc agcttgcttg gaatccagca ggcagctggg 2940
gctgagtgaa aacatctgca caactgggca ctggacagct tttccttctt ctccagtgtc 3000
taccttcctc ctcaactccc agccatctgt ataaacacaa tcctttgttc tcccaaatct 3060
gaatcgaatt actcttttgc ctccttttta atgtcagtaa ggatatgagc ctttgcacag 3120
gctggctgcg tgttcttgaa ataggtgtta ccttctctgg gccttggttt tttaaaatct 3180
gtaaaattag aggattgcac tagagaaact tgaatgctcc attcaggcct atcattttat 3240
taagtatgat tgacacagcc catgggccag aacacactct acaaaatgac taggataaca 3300
gaaagaacgt gatctcctga ttagagaggg tggttttcct caatggaacc aaatataaag 3360
aggacttgaa caaaaatgac agatacaaac tatttctatc ctgagtagta atctcacact 3420
tcatcctata gagtcaacca ccacagatag gaattcctta ttcttttttt aattttttta 3480
agacagagtc tcactttgtt gcccaggctg gagcgcagtg gggtgatctc atctccctgc 3540
aacctccgcc tcctgggttc aagcgattct tgtgcctcag cttcccaagc agctgggatt 3600
acaggtgccc gccaccacgc ccagctaatt tttgcatttt tagtagagat ggggtttcac 3660
catgttggcc acgctcgtct ccaactcctg acctcaggta atccgcctgc cttggcctcc 3720
caaagtgctg ggattacaga catgaaccac cacgcctggc tggaatactt actcttgtcg 3780
ggagattgaa ccactaaaat gttagagcag aattcattat gctgtggtca caggggtgtc 3840
ttgtctgaga acaaatacaa ttcagtcttc tctttggggt tttagtatgt gtcaaacata 3900
ggactggaag tttgcccctg ttcttttttc ttttgaaaga acatcagttc atgcctgagg 3960
catgagtgac tgtgcatttg agaatagttt tccctattct gtggatacag tcccagagtt 4020
ttcagggagt acacaggtag attagtttga agcattgacc ttttatttat tccttatttc 4080
tctttcatca aaacaaaaca gcagctgtgg gaggagaaat gagagggctt aaatgaaatt 4140
taaaataagc tatattatac aaatactatc tctgtattgt tctgaccctg gtaaatatat 4200
ttcaaaactt cagatgacaa ggattagaac actcattaaa gatgctattc ttcagaattg 4260
tttcatttgt atgatgtttc attttagaga agattttcat gatgaatggt taatgtgttc 4320
ttgcctgaag ttttatgtct gatccagatc tagctttttg tatcaaagtg tgccctaagg 4380
gaagatgcag atataatatg ttgaagttac aaggaggcag gtttcaattg gttaaaaaca 4440
atgacattca gacattgcaa ctgcatttgt tagcggttat tacagagtta atttctaccc 4500
tggatgggag gacacatttg aacatgctag gcctggatgc agaccctgag acaaaaggtt 4560
gaacaagtaa ttcatttgga aggaaatacc tcagtatcct tccaataatt tctcctctta 4620
gcttaagcta gtatggagtt agattcctac cgcttatgta tcaccatgcc cccttcctaa 4680
ataatacaga ggatatggtc agcattatca catatcatca gagattgagg tttgaaagaa 4740
aggaaatgag tagatgtaac taagaggttt gagaaaggaa tttcagcaga gttattgaag 4800
gagaagtcaa ggagaggaga aggagaggag cagtgaatgt tgtcgtgaag aggtgttgtc 4860
ttgaaatact gtattttttt cctccttttc ttttctgaac attcttgtgc tgacctttcc 4920
tctagtccaa cagaggcatt cacaattgcc tgtggagaat taggattgtc gcagcaggtc 4980
agcaaggaga aagtcatttt taagattaaa tttttaaaaa tgttttgaaa cttccaaaat 5040
aagttcttga acacctatgg agaggctttg aggaaagtta agggaatgat tttataccac 5100
aaaaataaat ggaaaaagaa taaagactgt gagaattcca tcttcctgcc ctttcctgtg 5160
cctcagatca ggtgagggtc atctgggtta gaaggggata gagccttgga ggaggcagag 5220
ggcagaaagc attgctgaga ttagagtcat ttggccctca gaaggaacag acaaagagaa 5280
ggaaattggc tggtgcatta atcatcacta gcttcaggga gctatgtgga ggccaaggca 5340
catcctacag atcatcgctt accactcatg aggacgctac aagttacctg ggcagagaag 5400
gtgcctgaga atatttccta atcgttttga gaagtgcctt cctgtgacat cttatgtatt 5460
tcctaattga tcaaaagtag tgctgcttct ctaagccctg agatttaatg agccccattc 5520
aaactgttat taatgtaacc ttctttccca gtgcaggatg acttgtaatc accttgaaag 5580
agaaggaggg ttcttcgtat tcaggtaggg tatggtaggg atgtggagtg ccaagcagga 5640
aatctgacaa gtgacccccg gaactttgga ttacctagca actagccagg taactggcta 5700
atctgattga gggttgccct ctttgctggg cagatcatgg ctaatctcag cttcacatga 5760
gtcttgtgaa ccatctagtt gttttgtaac tgctaagagc tgcaagtgct gagcagctgg 5820
tttatacagc attccctgaa acagcctagt atgtgtccat ttatgtgccc ggcttattat 5880
gtgtccactt atgtgtccaa ttagtaatca ctttttcttt cggtcaaggt atgtgtatta 5940
atcaatattt tttgaaccaa aaaa 5964
<210> 158
<211> 970
<212> DNA
<213>Artificial sequence (unknown)
<400> 158
ctcccctcac cccggtccag gatgcccagt ccccacgaca cctcccactt cccactgtgg 60
cctgggtggg ctcaggggct gcccttgacc tggcctagag ccctccccca gctggtggtg 120
gagctggcac tctctgggag ggagggggct gggagggaat gagtgggaat ggcaagaggc 180
cagggtttgg tgggatcagg ttgaggcagg tttggtttcc ttaaaatgcc aagttggggg 240
ccagtggggc ccacatataa atcctcaccc tgggagcctg gctgccttgc tctccttcct 300
gggtctgtct ctgccacctg gtctgccaca gatccatgat gtgcagttct ctggagcagg 360
cgctggctgt gctggtcact accttccaca agtactcctg ccaagagggc gacaagttca 420
agctgagtaa gggggaaatg aaggaacttc tgcacaagga gctgcccagc tttgtggggg 480
agaaagtgga tgaggagggg ctgaagaagc tgatgggcag cctggatgag aacagtgacc 540
agcaggtgga cttccaggag tatgctgttt tcctggcact catcactgtc atgtgcaatg 600
acttcttcca gggctgccca gaccgaccct gaagcagaac tcttgacttc ctgccatgga 660
tctcttgggc ccaggactgt tgatgccttt gagttttgta ttcaataaac tttttttgtc 720
tgttgataat attttaattg ctcagtgatg ttccataacc cggctggctc agctggagtg 780
ctgggagatg agggcctcct ggatcctgct cccttctggg ctctgactct cctggaaatc 840
tctccaaggc cagagctatg ctttaggtct caattttgga atttcaaaca ccagcaaaaa 900
attggaaatc gagataggtt gctgactttt attttgtcaa ataaagatat taaaaaaggc 960
aaaaaaaaaa 970
<210> 159
<211> 1863
<212> DNA
<213>Artificial sequence (unknown)
<400> 159
gccggcgcgc ccctgggagg gtgagccggc gccgggccca ggcccggacc tggtgggagg 60
cggggggagg tggggacgag gcctggggag gcgggccccg cccatctgca ggtggctgtg 120
aacgctgagc ggctccaggc gggggccggg cccgggggcg gggtctgtgg cgcgcgtccc 180
cgccacgtgt ccccggtcac cggccctgcc cccgggccct gtgcttataa cctgggatgg 240
gcacccctgc cagtcctgct ctgccgcctg ccaccgctgc ccgagcccga gtggttcact 300
gcactgtgaa aacagattcc agacgccggg aactcacgcc tccaatccca gacgctatgt 360
ccagcaaagg ctccgtggtt ctggcctaca gtggcggcct ggacacctcg tgcatcctcg 420
tgtggctgaa ggaacaaggc tatgacgtca ttgcctatct ggccaacatt ggccagaagg 480
aagacttcga ggaagccagg aagaaggcac tgaagcttgg ggccaaaaag gtgttcattg 540
aggatgtcag cagggagttt gtggaggagt tcatctggcc ggccatccag tccagcgcac 600
tgtatgagga ccgctacctc ctgggcacct ctcttgccag gccctgcatc gcccgcaaac 660
aagtggaaat cgcccagcgg gagggggcca agtatgtgtc ccacggcgcc acaggaaagg 720
ggaacgatca ggtccggttt gagctcagct gctactcact ggccccccag ataaaggtca 780
ttgctccctg gaggatgcct gaattctaca accggttcaa gggccgcaat gacctgatgg 840
agtacgcaaa gcaacacggg attcccatcc cggtcactcc caagaacccg tggagcatgg 900
atgagaacct catgcacatc agctacgagg ctggaatcct ggagaacccc aagaaccaag 960
cgcctccagg tctctacacg aagacccagg acccagccaa agcccccaac acccctgaca 1020
ttctcgagat cgagttcaaa aaaggggtcc ctgtgaaggt gaccaacgtc aaggatggca 1080
ccacccacca gacctccttg gagctcttca tgtacctgaa cgaagtcgcg ggcaagcatg 1140
gcgtgggccg tattgacatc gtggagaacc gcttcattgg aatgaagtcc cgaggtatct 1200
acgagacccc agcaggcacc atcctttacc atgctcattt agacatcgag gccttcacca 1260
tggaccggga agtgcgcaaa atcaaacaag gcctgggctt gaaatttgct gagctggtgt 1320
ataccggttt ctggcacagc cctgagtgtg aatttgtccg ccactgcatc gccaagtccc 1380
aggagcgagt ggaagggaaa gtgcaggtgt ccgtcctcaa gggccaggtg tacatcctcg 1440
gccgggagtc cccactgtct ctctacaatg aggagctggt gagcatgaac gtgcagggtg 1500
attatgagcc aactgatgcc accgggttca tcaacatcaa ttccctcagg ctgaaggaat 1560
atcatcgtct ccagagcaag gtcactgcca aatagacccg tgtacaatga ggagctgggg 1620
cctcctcaat ttgcagatcc cccaagtaca ggcgctaatt gttgtgataa tttgtaattg 1680
tgacttgttc tccccggctg gcagcgtagt ggggctgcca ggccccagct ttgttccctg 1740
gtccccctga agcctgcaaa cgttgtcatc gaagggaagg gtggggggca gctgcggtgg 1800
ggagctataa aaatgacaat taaaagagac actagtcttt tatttctaaa aaaaaaaaaa 1860
aaa 1863
<210> 160
<211> 423
<212> DNA
<213>Artificial sequence (unknown)
<400> 160
actccgcctt ccacgtgcac ccactgcctc ttcccttctc gcttgggaac tctagtctcg 60
cctcgggttg caatggaccc caactgctcc tgtgccgctg caggtgtctc ctgcacctgc 120
gccagctcct gcaagtgcaa agagtgcaaa tgcacctcct gcaagaagag ctgctgctcc 180
tgctgccctg tgggctgtgc caagtgtgcc cagggctgca tctgcaaagg ggcatcggag 240
aagtgcagct gctgcgcctg atgtcgggac agccctgctc ccaagtacaa atagagtgac 300
ccgtaaaatc caggattttt tgttttttgc tacaatcttg acccctttgc tacattcctt 360
tttttctgtg aaatatgtga ataataatta aacacttaga cttgaaaaaa aaaaaaaaaa 420
aaa 423
<210> 161
<211> 6012
<212> DNA
<213>Artificial sequence (unknown)
<400> 161
ataacctcca ctctgaaagc agtcttcaca gaaacttttc acagaagtca aatagttaaa 60
gcaaattcta gatacatggt agagaccagg agaaaatatg aataactttc ttctaaacaa 120
ggagctcagt ggataaacca tacctctaga ttccttgctt ccattttccc agaagttttg 180
gtagcaggat gatgttggcc tcataatgtg agttagagag gagtccctct ttttcgactg 240
tttggaattg tttcagaagg aatgctacca gctcctcttg taccactggt agaattcagc 300
tgtgaatctg tctggtcctg ggcttttttt gattgacaag atgaggaaga gaaagatcag 360
tgtgtgtcaa caaacttggg ccttattatg caagaacttt cttaaaaaat ggagaatgaa 420
aagagagtcc ttaatggaat ggctgaattc attgctccta ctactttgtt tgtatatata 480
tcctcatagt catcaagtaa atgatttttc ttcactgctt accatggacc tgggacgggt 540
agatacattt aatgaatcca gattttctgt tgtatacaca cctgtcacca acacgaccca 600
acagataatg aataaagtag cctctactcc cttcctggca ggtaaagagg tcttgggact 660
gccagatgag gaaagtatta aagaattcac agcaaattat cctgaagaaa tagtaagagt 720
cacctttact aatacatact catatcattt gaagttcttg ctaggacatg gaatgccagc 780
aaagaaggag cacaaggacc atacagctca ttgttatgaa acaaatgaag atgtttactg 840
tgaagtttca gtattttgga aggaaggttt tgtggctctt caagctgcca ttaatgctgc 900
tattatagaa atcacaacaa atcactcagt gatggaggag ctgatgtcag ttactggaaa 960
aaatatgaag atgcattcct tcattggtca atcaggagtt ataactgatt tgtacctttt 1020
ttcctgcatt atttcatttt cctcattcat ttactatgca tctgttaatg tcacaagaga 1080
gaggaaaagg atgaaggcct tgatgacaat gatgggtctt cgggattcag cgttctggct 1140
ctcctggggt ttgctctatg ctggtttcat cttcattatg gcccttttct tggcacttgt 1200
tataagatct acccagttta tcattttgtc tggcttcatg gtagtcttca gcctctttct 1260
cctgtatgga ttatctttgg tagctttggc tttcttaatg agcatcttgg taaagaaatc 1320
tttcctcacc ggcctggtcg tgttcctcct cactgtcttt tgggggtgtc tggggttcac 1380
atcactgtac agacaccttc ctgcatcctt ggagtggatt ttaagcttgc ttagtccctt 1440
tgccttcatg cttggaatgg cccagctttt acacttggac tatgatttga attctaatgc 1500
atttcctcat ccatcggacg gctcaaatct cattgtagca acaaatttca tgttggcatt 1560
tgacacttgc ctctatctgg cattggcgat ttactttgaa aaaattttgc caaatgaata 1620
tggacatcga cgtccacctt tgtttttcct gaagtcctca ttttggtctc aaacacaaaa 1680
gactgatcac gtggcccttg aagatgaaat ggatgccgat ccttcatttc atgactcttt 1740
tgaacaagcg cctccagaat tccaagggaa agaagccatc agaatcagaa atgttacaaa 1800
agaatataaa ggaaagcctg ataaaataga agccttgaaa gatctggtat ttgacattta 1860
cgaaggccaa atcactgcaa tacttggtca cagtggagct ggaaagtcaa cactgctaaa 1920
cattcttagt gggttgtctg ttcccaccaa aggttcagtc accatctata acaataagct 1980
ttcagaaatg gctgacctag aaaatctcag caagctgacc ggagtttgtc cacaatccaa 2040
tgtgcaattt gacttcctca ctgtaagaga aaacctcaga ctctttgcta aaataaaagg 2100
gattctgcca caagaagtgg ataaagagat acaaagggtt ctgctggaat tggaaatgaa 2160
aaatattcag gatgttcttg ctcaaaactt aagtggtgga cagaaaagaa agctaacctt 2220
tgggattgcc attttaggag atcctcagat tttcctgttg gatgaaccaa ctgctggatt 2280
ggatcccttt tcaagacacc aagtatggaa ccttctgaaa gaacgcaaaa cagaccgcgt 2340
gatcctcttc agtacccagt tcatggatga ggccgacatc ctggcggaca ggaaagtatt 2400
tctctcccaa gggaagctaa agtgcgcggg ctcttctttg tttctaaaga agaaatgggg 2460
gattggatat cacttaagct tgcagttaaa tgaaatatgt gttgaggaaa acataacatc 2520
acttgttaaa cagcacatcc ctgatgccaa attatcagcc aaaagcgaag gaaaacttat 2580
ttatacatta cccttagaaa gaacaaataa atttccagaa ctttacaagg atcttgatag 2640
ctatcctgac ctaggaattg agaattatgg tgtttccatg acaactttga atgaagtatt 2700
cctgaagcta gaaggaaaat ctacaattaa tgaatcggac attgctattt tgggagaagt 2760
acaagcggaa aaagctgacg acactgaaag gcttgttgag atggaacaag tcctctcttc 2820
acttaacaag atgagaaaga caataggtgg tgtggctctc tggcgacagc aaatctgcgc 2880
aattgcaagg gttcgcttgt taaagttaaa gcatgaaaga aaagctcttt tagcactgct 2940
attaattcta atggctggat tttgccctct tcttgtggag tataccatgg tgaaaatata 3000
tcaaaacagt tacacctggg aactttctcc tcatttgtat ttccttgctc ctggacaaca 3060
accacatgac cctctcactc aactactgat catcaataaa acaggggcaa gcattgatga 3120
ctttatacag tctgtggagc accagaacat agctttagaa gtggatgcat ttggaactag 3180
aaatggcaca gatgacccat cttataatgg agccatcaca gtgtgttgta atgaaaagaa 3240
ttacagcttt tcgttagcat gcaatgccaa aagattgaat tgcttcccag ttcttatgga 3300
cattgttagt aatgggctac ttggaatggt taaaccatca gtacatatcc gaactgaaag 3360
aagtacattt ttggagaatg gacaggacaa tccaatcgga ttcctggcat atatcatgtt 3420
ctggctggtt ttaacatcga gttgcccacc ttacattgcc atgagcagca tcgatgatta 3480
taagaacaga gctcggtccc agctacggat ttccggactc tccccttctg cttactggtt 3540
tgggcaggcg ctggtggatg tttccctgta cttcttggtc ttcgttttta tatatttaat 3600
gagctacatt tcaaacttcg aagacatgct acttacaata attcatatta ttcaaatccc 3660
atgtgctgtt ggttattcct tttccctcat cttcatgaca tacgtgattt ccttcatctt 3720
tcgcaagggg agaaaaaata gtggcatttg gtcattttgt ttctatgttg tcactgtatt 3780
ctctgtggct ggatttgcgt tcagtatctt cgaaagtgat attccattta tcttcacttt 3840
tttaatacca cctgccacaa tgattggctg tttgttctta tcttctcatc ttctcttttc 3900
ttctctcttt tctgaagaac gaatggatgt acagccattt ctggtattcc taattccttt 3960
ccttcatttt atcatttttc tttttactct tcgatgtctg gaatggaagt ttggaaagaa 4020
atcaatgaga aaggatcctt tctttagaat ttctccaaga agtagtgatg tgtgtcaaaa 4080
tccagaagaa ccagaaggag aggatgaaga tgttcagatg gaaagagtga gaacagcaaa 4140
tgccttgaat tctactaatt ttgatgagaa gccagtcatc attgccagct gtctacgcaa 4200
ggagtatgca gggaagagga aaggctgttt ttccaagagg aagaataaga tagccacgag 4260
aaatgtctcc ttctgtgtta gaaaaggtga agttttagga ttattaggac acaatggagc 4320
tggtaaaagc acatccatta aggtgataac tggagacaca aaaccaactg ctggacaagt 4380
gctactgaaa gggagcggtg gaggggatgc cctggagttc ctggggtact gccctcagga 4440
gaacgcgctg tggcccaacc tgacagtgag gcagcacctg gaggtgtacg ccgccgtgaa 4500
agggctgagg aaaggggatg ctgaggttgc catcacacgg ttagtggatg cgctcaagct 4560
gcaggaccag ctgaagtctc ccgtgaagac cttgtcagag ggaataaaga gaaagctgtg 4620
ctttgtcctg agcatactgg ggaacccgtc agtggtgctt ctggatgagc cgtcgaccgg 4680
gatggacccc gaggggcagc agcaaatgtg gcaggccatc cgggccacct ttagaaacac 4740
ggaaaggggt gccctcctaa ccacccacta catggcagag gctgaggccg tgtgtgaccg 4800
agtggccatc atggtatctg ggaggttgag atgtatcggt tccatccaac acctgaaaag 4860
caaatttggc aaagattacc tgctggagat gaaggtgaag aacctggcac aagtggagcc 4920
cctccatgca gagatcctga ggcttttccc ccaggctgct cggcaggaaa ggtactcctc 4980
tctgatggtt tataagttgc cagtggaaga tgtgcaacct ttagcccaag ctttcttcaa 5040
attagagaag gttaaacaga gctttgacct agaggagtac agcctctcac agtctaccct 5100
ggagcaggtt ttcctggagc tctccaagga gcaggagctg ggtgattttg aggaggattt 5160
tgatccctca gtgaagtgga agctcctccc ccaggaagag ccttaaaacc ccaaattctg 5220
tgttcctgtt taaacccgtg gtttttttta aatacattta tttttatagc agcaatgttc 5280
tatttttaga aactatatta taagtacaga aatggttctc cgtgtggtgg gaggaggagg 5340
ttcgggtgct gggtaagtgc catgtcagtg tggacagagg catttgacta agccaacctc 5400
ctctcacagc ctctgtatct ctgcaggcca tactggttcc attgttctgt ataatactga 5460
ataaataaat ttacttttac atgatcgtat aagtttctag ataagataaa caaattttgt 5520
ttaaattttt ttaataaaaa tcttaaaaca ctttttttct aacctagact gagaaattca 5580
tgtttacttt tctaggtgta tgatactttg taaagttgat actttcctaa gaatttaaca 5640
tgtcatattt ttgaaataga tttaagtgtg cttcttattg ctaaaaatac taaatgtcat 5700
gggtcatagt atctgatatc aatatcgttg ataacatatc cacaggtaac accatgatgt 5760
aggcataaat ggaaaacaaa aaccctacta tttcaaatat attgtacttt tttatttctg 5820
taagccaact gtgtgccatt ttcactggac ttttaaatct agactttagt gatgtctaca 5880
ttgtaaatga tcttttgtgg atatttgtca cttggtttca gaaagttcac aaatgtagca 5940
acagctcaca tgactgagta ggtagaaaat gtgaaataaa tctcatatat atagttttga 6000
aataaaaaaa aa 6012
<210> 162
<211> 3668
<212> DNA
<213>Artificial sequence (unknown)
<400> 162
cattcataag actcagagct acggccacgg cagggacacg cggaaccaag acttggaaac 60
ttgattgttg tggttcttct tgggggttat gaaatttcat taatcttttt ttttccgggg 120
agaaagtttt tggaaagatt cttccagata tttcttcatt ttcttttgga ggaccgactt 180
actttttttg gtcttcttta ttactcccct ccccccgtgg gacccgccgg acgcgtggag 240
gagaccgtag ctgaagctga ttctgtacag cgggacagcg ctttctgccc ctgggggagc 300
aacccctccc tcgcccctgg gtcctacgga gcctgcactt tcaagaggta cagcggcatc 360
ctgtgggggc ctgggcaccg caggaagact gcacagaaac tttgccattg ttggaacggg 420
acgttgctcc ttccccgagc ttccccggac agcgtacttt gaggactcgc tcagctcacc 480
ggggactccc acggctcacc ccggacttgc accttacttc cccaacccgg ccatagcctt 540
ggcttcccgg cgacctcagc gtggtcacag gggcccccct gtgcccaggg aaatgtttca 600
ggctttcccc ggagactacg actccggctc ccggtgcagc tcctcaccct ctgccgagtc 660
tcaatatctg tcttcggtgg actccttcgg cagtccaccc accgccgccg cctcccagga 720
gtgcgccggt ctcggggaaa tgcccggttc cttcgtgccc acggtcaccg cgatcacaac 780
cagccaggac ctccagtggc ttgtgcaacc caccctcatc tcttccatgg cccagtccca 840
ggggcagcca ctggcctccc agcccccggt cgtcgacccc tacgacatgc cgggaaccag 900
ctactccaca ccaggcatga gtggctacag cagtggcgga gcgagtggca gtggtgggcc 960
ttccaccagc ggaactacca gtgggcctgg gcctgcccgc ccagcccgag cccggcctag 1020
gagaccccga gaggagacgg agacagatca gttggaggaa gaaaaagcag agctggagtc 1080
ggagatcgcc gagctccaaa aggagaagga acgtctggag tttgtgctgg tggcccacaa 1140
accgggctgc aagatcccct acgaagaggg gcccgggccg ggcccgctgg cggaggtgag 1200
agatttgccg ggctcagcac cggctaagga agatggcttc agctggctgc tgccgccccc 1260
gccaccaccg cccctgccct tccagaccag ccaagacgca ccccccaacc tgacggcttc 1320
tctctttaca cacagtgaag ttcaagtcct cggcgacccc ttccccgttg ttaacccttc 1380
gtacacttct tcgtttgtcc tcacctgccc ggaggtctcc gcgttcgccg gcgcccaacg 1440
caccagcggc agtgaccagc cttccgatcc cctgaactcg ccctccctcc tcgctctgtg 1500
aactctttag acacacaaaa caaacaaaca catgggggag agagacttgg aagaggagga 1560
ggaggaggag aaggaggaga gagaggggaa gagacaaagt gggtgtgtgg cctccctggc 1620
tcctccgtct gaccctctgc ggccactgcg ccactgccat cggacaggag gattccttgt 1680
gttttgtcct gcctcttgtt tctgtgcccc ggcgaggccg gagagctggt gactttgggg 1740
acagggggtg ggaaggggat ggacaccccc agctgactgt tggctctctg acgtcaaccc 1800
aagctctggg gatgggtggg gaggggggcg ggtgacgccc accttcgggc agtcctgtgt 1860
gaggattaag ggacgggggt gggaggtagg ctgtggggtg ggctggagtc ctctccagag 1920
aggctcaaca aggaaaaatg ccactcccta cccaatgtct cccacaccca cccttttttt 1980
ggggtgccta ggttggtttc ccctgcactc ccgaccttag cttattgatc ccacatttcc 2040
atggtgtgag atcctcttta ctctgggcag aagtgagccc cccccttaaa gggaattcga 2100
tgccccccta gaataatctc atccccccac ccgacttctt ttgaaatgtg aacgtccttc 2160
cttgactgtc tagccactcc ctcccagaaa aactggctct gattggaatt tctggcctcc 2220
taaggctccc caccccgaaa tcagccccca gccttgtttc tgatgacagt gttatcccaa 2280
gaccctgccc cctgccagcc gaccctcctg gccttcctcg ttgggccgct ctgatttcag 2340
gcagcagggg ctgctgtgat gccgtcctgc tggagtgatt tatactgtga aatgagttgg 2400
ccagattgtg gggtgcagct gggtggggca gcacacctct ggggggataa tgtccccact 2460
cccgaaagcc tttcctcggt ctcccttccg tccatccccc ttcttcctcc cctcaacagt 2520
gagttagact caagggggtg acagaaccga gaagggggtg acagtcctcc atccacgtgg 2580
cctctctctc tctcctcagg accctcagcc ctggcctttt tctttaaggt cccccgacca 2640
atccccagcc taggacgcca acttctccca ccccttggcc cctcacatcc tctccaggaa 2700
gggagtgagg ggctgtgaca tttttccgga gaagatttca gagctgaggc tttggtaccc 2760
ccaaaccccc aatatttttg gactggcaga ctcaaggggc tggaatctca tgattccatg 2820
cccgagtccg cccatccctg accatggttt tggctctccc accccgccgt tccctgcgct 2880
tcatctcatg aggatttctt tatgaggcaa atttatattt tttaatatcg gggggtggac 2940
cacgccgccc tccatccgtg ctgcatgaaa aacattccac gtgccccttg tcgcgcgtct 3000
cccatcctga tcccagaccc attccttagc tatttatccc tttcctggtt tccgaaaggc 3060
aattatatct attatgtata agtaaatata ttatatatgg atgtgtgtgt gtgcgtgcgc 3120
gtgagtgtgt gagcgcttct gcagcctcgg cctaggtcac gttggccctc aaagcgagcc 3180
gttgaattgg aaactgcttc tagaaactct ggctcagcct gtctcgggct gacccttttc 3240
tgatcgtctc ggcccctctg attgttcccg atggtctctc tccctctgtc ttttctcctc 3300
cgcctgtgtc catctgaccg ttttcacttg tctcctttct gactgtccct gccaatgctc 3360
cagctgtcgt ctgactctgg gttcgttggg gacatgagat tttatttttt gtgagtgaga 3420
ctgagggatc gtagattttt acaatctgta tctttgacaa ttctgggtgc gagtgtgaga 3480
gtgtgagcag ggcttgctcc tgccaaccac aattcaatga atccccgacc cccctacccc 3540
atgctgtact tgtggttctc tttttgtatt ttgcatctga ccccgggggg ctgggacaga 3600
ttggcaatgg gccgtcccct ctccccttgg ttctgcactg ttgccaataa aaagctctta 3660
aaaacgca 3668
<210> 163
<211> 2611
<212> DNA
<213>Artificial sequence (unknown)
<400> 163
gcgcgtccgg gctcccgggg ctggtaatat agcggctcgc cgaggcgctg gtgcacgggg 60
gcagcgcgca gcaggccggc gggcaggcgg gcgggctggc tggcaggcag gactgggatc 120
gaggcccaga aaacggagca gcgggcacca gggaggcctg gaacggggcg agcgccatga 180
gcaacaaatg cgacgtggtc gtggtggggg gcggcatctc aggtatggca gcagccaaac 240
ttctgcatga ctctggactg aatgtggttg ttctggaagc ccgggaccgt gtgggaggca 300
ggacttacac tcttaggaac caaaaggtta aatatgtgga ccttggagga tcctatgttg 360
gaccaaccca gaatcgtatc ttgagattag ccaaggagct aggattggag acctacaaag 420
tgaatgaggt tgagcgtctg atccaccatg taaagggcaa atcatacccc ttcagggggc 480
cattcccacc tgtatggaat ccaattacct acttagatca taacaacttt tggaggacaa 540
tggatgacat ggggcgagag attccgagtg atgccccatg gaaggctccc cttgcagaag 600
agtgggacaa catgacaatg aaggagctac tggacaagct ctgctggact gaatctgcaa 660
agcagcttgc cactctcttt gtgaacctgt gtgtcactgc agagacccat gaggtctctg 720
ctctctggtt cctgtggtat gtgaagcagt gtggaggcac aacaagaatc atctcgacaa 780
caaatggagg acaggagagg aaatttgtgg gcggatctgg tcaagtgagt gagcggataa 840
tggacctcct tggagaccga gtgaagctgg agaggcctgt gatctacatt gaccagacaa 900
gagaaaatgt ccttgtggag accctaaacc atgagatgta tgaggctaaa tatgtgatta 960
gtgctattcc tcctactctg ggcatgaaga ttcacttcaa tccccctctg ccaatgatga 1020
gaaaccagat gatcactcgt gtgcctttgg gttcagtcat caagtgtata gtttattata 1080
aagagccttt ctggaggaaa aaggattact gtggaaccat gattattgat ggagaagaag 1140
ctccagttgc ctacacgttg gatgatacca aacctgaagg caactatgct gccataatgg 1200
gatttatcct ggcccacaaa gccagaaaac tggcacgtct taccaaagag gaaaggttga 1260
agaaactttg tgaactctat gccaaggttc tgggttccct agaagctctg gagccagtgc 1320
attatgaaga aaagaactgg tgtgaggagc agtactctgg gggctgctac acaacttatt 1380
tcccccctgg gatcctgact caatatggaa gggttctacg ccagccagtg gacaggattt 1440
actttgcagg caccgagact gccacacact ggagcggcta catggagggg gctgtagagg 1500
ccggggagag agcagcccga gagatcctgc atgccatggg gaagattcca gaggatgaaa 1560
tctggcagtc agaaccagag tctgtggatg tccctgcaca gcccatcacc accacctttt 1620
tggagagaca tttgccctcc gtgccaggcc tgctcaggct gattggattg accaccatct 1680
tttcagcaac ggctcttggc ttcctggccc acaaaagggg gctacttgtg agagtctaaa 1740
gagagagggt gtctgtaatc acactctctt cttactgtat ttgggatatg agtttgggga 1800
aagagttgca gtaaagttcc atgaagacaa atagtgtgga gtgaggcggg gagcatgaag 1860
ataaatccaa ctctgactgt aaaatacatg gtatctcttt ctccgttgtg gcccctgctt 1920
agtgtccctt acctggctta gcgttctgtt tcaccagttt ccaagtttat tgccctcaaa 1980
atctttagaa tagttaaatt ggcttgttta aggttcttgc tgccccacaa cacaccttgc 2040
ccatgcacaa ggaatgaatt ttttcctacc attatggctt tgtgcttgtt cttcctctta 2100
cctgtaatag cctcaccttc cctagttctt tgcattcgtc cttagaatac tgtattgtta 2160
cagctgaaag acagtaaaga ccatttagtc ctcaccttct gttttagagt tgagcaaact 2220
gaagcccaca gaggtggaac ttaattacct aagagccaca ataagccact ggtatctggg 2280
ggactagaac acaaatccaa cgcttttccc acctctttgg atgttttccc caattatcct 2340
ccttcactcc ctgtcatagt taccgatggt gtcccgttgt gtgggtttac tctgtgctaa 2400
gttgtcttac acttctcaaa tgctactcag tatatagcct taagtcttac tgttttgtgc 2460
ggtgtgtctc cagctgattt taactttttt gatggtagaa attttatctc ttcttccttt 2520
tgtatcctcc attgtatctt catacaaagg acagtacaca cttgggtaat taaaaataaa 2580
agttgattga ccataaaaaa aaaaaaaaaa a 2611
<210> 164
<211> 1195
<212> DNA
<213>Artificial sequence (unknown)
<400> 164
ggttaaaaag caatttggga cttcctcttt gaacagttgc cttttcctct cacagaagga 60
agatttcatt ttgtttgaga cgagaaacca aaccacacac caaagagagg ggtatgatgg 120
ctaagaagcc cccaaaacca gcccctcgca ggatcttcca ggaaaggtta aagattactg 180
ctctaccttt gtactttgaa ggttttttat taatcaagcg gtcaggatac cgggagtatg 240
agcattactg gacagagttg agaggaacta ctcttttctt ttataccgac aaaaagagta 300
taatatatgt tgacaaatta gacatagtag acctcacatg ccttactgag cagaattcaa 360
ctgaaaagaa ctgtgcgaaa ttcacccttg ttttgccgaa agaggaagta caactgaaga 420
cagagaacac agaaagtggg gaagaatgga gaggcttcat tcttacagta acagagctgt 480
cagttcccca aaacgtgtca ctcctacctg ggcaagtaat taaactgcat gaagtcctag 540
agagagaaaa gaaaaggagg attgagacag agcagagtac gtccgtggaa aaagagaagg 600
aaccaactga agattatgtg gatgtactga accctatgcc agcatgtttt tatacagtgt 660
cccggaaaga ggcaactgag atgctccaga agaacccttc tttgggaaat atgatcctga 720
ggcctggtag tgacagtaga aactactcca tcactattcg gcaggagata gacattccaa 780
gaatcaagca ctacaaagtg atgagcgtag gacaaaacta cactattgaa ctggaaaaac 840
ctgtaacact cccaaacctt ttcagtgtca ttgattattt tgtgaaggag actcgaggaa 900
atttaagacc atttatatgt tcaactgatg aaaacactgg tcaagaaccc agtatggaag 960
ggagaagtga aaagttgaag aaaaatccac acattgcatg aaatacaatg tgaaagctcc 1020
tttgtatatc ttggggaaag actatgtgag acagagggag aaaacagcca ttgacaactc 1080
aaggagagag gcctcggggg gaaaaaaaga tcaacctggc caaaaccttg aaaatccggc 1140
ttcttgactt gtgagaaaat aaatttgtgt tccttaaaaa aaaaaaaaaa aaaaa 1195
<210> 165
<211> 2411
<212> DNA
<213>Artificial sequence (unknown)
<400> 165
attactgaca caaacgctcc ctcagggcgt ccccgtctgg actacaggag aaagtttggg 60
aggcaggttc aacttttcaa cttggcgggg aattcctctc cctcttacac agtttgcagc 120
gcgggggcgg cggggtgaca gtccccgtgc atgaatcagc cacccctcag gctccgcccc 180
ggcgggggtc ggccggacgc tcgccccgca taaagcgggc acccgggccg cctggagcag 240
aaagccgcgc acctcctccc gccaggcgct ttctcggacg ccttgcccag cgggccgccc 300
gaccccctgc accatggacc ccgctcgccc cctggggctg tcgattctgc tgcttttcct 360
gacggaggct gcactgggcg atgctgctca ggagccaaca gactacggac cctgccgggc 420
cctacttctc cgttactact acgacaggta cacgcagagc tgccgccagt tcctgtacgg 480
gggctgcgag ggcaacgcca acaatttcta cacctgggag gcttgcgacg atgcttgctg 540
gaggatagaa aaagttccca aagtttgccg gctgcaagtg agtgtggacg accagtgtga 600
ggggtccaca gaaaagtatt tctttaatct aagttccatg acatgtgaaa aattcttttc 660
cggtgggtgt caccggaacc ggattgagaa caggtttcca gatgaagcta cttgtatggg 720
cttctgcgca ccaaagaaaa ttccatcatt ttgctacagt ccaaaagatg agggactgtg 780
ctctgccaat gtgactcgct attattttaa tccaagatac agaacctgtg atgctttcac 840
ctatactggc tgtggaggga atgacaataa ctttgttagc agggaggatt gcaaacgtgc 900
atgtgcaaaa gctttgaaaa agaaaaagaa gatgccaaag cttcgctttg ccagtagaat 960
ccggaaaatt cggaagaagc aattttaaac attcttaata tgtcatcttg tttgtcttta 1020
tggcttattt gcctttatgg ttgtatctga agaataatat gacagcatga ggaaacaaat 1080
cattggtgat ttattcacca gtttttatta atacaagtca ctttttaaaa aatttggatt 1140
tttttatata taactagctg ctattcaaat gtgagtctac catttttaat ttatggttca 1200
actgtttgtg agactgaatt cttgcaatgc ataagatata aaagcaaata tgactcactc 1260
atttcttggg gtcgtattcc tgatttcaga agaggatcat aactgaaaca acataagaca 1320
atataatcat gtgcttttaa catatttgag aataaaaagg actagcaaat aaaactcatt 1380
ttgcatttaa aagttggatt atattttagt cccaagaaga caaagtcgca gattaacaac 1440
actttaaaaa tattactccc attttattgt gttagattgc agtacaatga atgaataagg 1500
ggatttattt aaaagatctt aactttcttg actgatttaa aaagctaatc aatttattaa 1560
agccagaaat gttctcctct gggaaagcaa tttctatcta tttatctacc aatccccact 1620
cacatgtata tgtttgtgtt tacatagaga tagatggttt taagggtttt cctattgtta 1680
aattatttcc taagacattg tgggttggag accactaaac ttataaaaaa ccaaggaaag 1740
taaagttttt caaatgttta tactgtttaa ggtgtttatt tatataaacc atgcatgaga 1800
aaccatgcat aaatttaata atttaaattt caccagtaaa ttatcattga ttaaatatgg 1860
tcataccaat gaaataggtt ttttctttct ctgtaataaa acaatttttc taaattctta 1920
tgttttcata gcaagattaa catatttaat tacaaattaa atatgcaaaa tgacaaatgc 1980
gtttaccttt tgcttgaaca atctttcatt taaaaattta tcccagttat tttgacaaat 2040
aggtatatgc ctgagaactt tgaatgatgc tgaaagctag aagcaaacca ggtactcttc 2100
agtcagggac tggttgaaga ttttatggat gaggagttag caaaatatct atatatgcat 2160
atcttctgac tcccaggata cataagaaac acagggccta gaacagtatg aataaacaca 2220
catatacaca aacatcacag aagatactaa agatattaaa aatgtttacc tatagaggtt 2280
tggagagaac agaggggtgg acagttgtgg agataatatt tgtgtaaata taactgtgat 2340
atagttttta tcttggacca tgtaaatatt tgacataatt aataatcaaa attaaataaa 2400
aaagaaaaag c 2411
<210> 166
<211> 1098
<212> DNA
<213>Artificial sequence (unknown)
<400> 166
gtaagaaacg gttgaactgg atgcaatttt tatcacagct tgtgtaagac tgcctctgtc 60
cctcctctca catgccattg gttaaccagc agacagtgtg ctcaggggcg ttgccagctc 120
attgctctta tagcctgtga gggaggaaga aacatttgct aaccaggcca gtgacagaaa 180
tggattcgaa ataccagtgt gtgaagctga atgatggtca cttcatgcct gtcctgggat 240
ttggcaccta tgcgcctgca gaggttccta aaagtaaagc tctagaggcc gtcaaattgg 300
caatagaagc cgggttccac catattgatt ctgcacatgt ttacaataat gaggagcagg 360
ttggactggc catccgaagc aagattgcag atggcagtgt gaagagagaa gacatattct 420
acacttcaaa gctttggagc aattcccatc gaccagagtt ggtccgacca gccttggaaa 480
ggtcactgaa aaatcttcaa ttggactatg ttgacctcta tcttattcat tttccagtgt 540
ctgtaaagga ggacataggg attttaacat ggaagaagag ccctaaacat aactcctaat 600
tcctttctat ggaacagaaa gcaattttga atccatactt ccgtgattgc atgtctacaa 660
gaaaagagag tgcagaatcc tcaaagcctc tgcctcaaaa acttgaggaa atgacaatca 720
tctccttgaa ggcacaaggt cttatttatg attcctgatt tcacctcttg ggatgttcac 780
agacacagag tttcatgaag ctgtggtgtc cagaaaacct gctgcacata gggtgcacaa 840
tgagtttcca tcttcttgcc tcttttcaag gggcaagaac tcagtccggg aatgtcttaa 900
actacaaacc ttcatgggaa accttgttgc ttctgcttcc tctcttttca cactggaggt 960
tttatttttg cttagccatg aattcttgtg tcattcataa cttttgtctt aaggtactga 1020
aaactagtca ggctagttaa tgcaaaaggg tatattagat atgataatgg gaaatcaaag 1080
ccagggctac attaagaa 1098
<210> 167
<211> 980
<212> DNA
<213>Artificial sequence (unknown)
<400> 167
gcggcggcgg gcagcagctg cgctgcgact gctctggaag gagaggacgg ggcacaaacc 60
ctgaccatga ccccccacag gctgctgcca ccgctgctgc tgctgctagc tctgctgctc 120
gctgccagcc caggaggcgc cttggcgcgg tgcccaggct gcgggcaagg ggtgcaggcg 180
ggttgtccag ggggctgcgt ggaggaggag gatggggggt cgccagccga gggctgcgcg 240
gaagctgagg gctgtctcag gagggagggg caggagtgcg gggtctacac ccctaactgc 300
gccccaggac tgcagtgcca tccgcccaag gacgacgagg cgcctttgcg ggcgctgctg 360
ctcggccgag gccgctgcct tccggcccgc gcgcctgctg ttgcagagga gaatcctaag 420
gagagtaaac cccaagcagg cactgcccgc ccacaggatg tgaaccgcag agaccaacag 480
aggaatccag gcacctctac cacgccctcc cagcccaatt ctgcgggtgt ccaagacact 540
gagatgggcc catgccgtag acatctggac tcagtgctgc agcaactcca gactgaggtc 600
taccgagggg ctcaaacact ctacgtgccc aattgtgacc atcgaggctt ctaccggaag 660
cggcagtgcc gctcctccca ggggcagcgc cgaggtccct gctggtgtgt ggatcggatg 720
ggcaagtccc tgccagggtc tccagatggc aatggaagct cctcctgccc cactgggagt 780
agcggctaaa gctgggggat agaggggctg cagggccact ggaaggaaca tggagctgtc 840
atcactcaac aaaaaaccga ggccctcaat ccaccttcag gccccgcccc atgggcccct 900
caccgctggt tggaaagagt gttggtgttg gctggggtgt caataaagct gtgcttgggg 960
tcgctgaaaa aaaaaaaaaa 980
<210> 168
<211> 4193
<212> DNA
<213>Artificial sequence (unknown)
<400> 168
cttcttctcg ctgagtctcc tcctcggctc tgacggtaca gtgatataat gatgatgggt 60
gtcacaaccc gcatttgaac ttgcaggcga gctgccccga gcctttctgg ggaagaactc 120
caggcgtgcg gacgcaacag ccgagaacat taggtgttgt ggacaggagc tgggaccaag 180
atcttcggcc agccccgcat cctcccgcat cttccagcac cgtcccgcac cctccgcatc 240
cttccccggg ccaccacgct tcctatgtga cccgcctggg caacgccgaa cccagtcgcg 300
cagcgctgca gtgaattttc cccccaaact gcaataagcc gccttccaag gccaagatgt 360
tcataaatat aaagagcatc ttatggatgt gttcaacctt aatagtaacc catgcgctac 420
ataaagtcaa agtgggaaaa agcccaccgg tgaggggctc cctctctgga aaagtcagcc 480
taccttgtca tttttcaacg atgcctactt tgccacccag ttacaacacc agtgaatttc 540
tccgcatcaa atggtctaag attgaagtgg acaaaaatgg aaaagatttg aaagagacta 600
ctgtccttgt ggcccaaaat ggaaatatca agattggtca ggactacaaa gggagagtgt 660
ctgtgcccac acatcccgag gctgtgggcg atgcctccct cactgtggtc aagctgctgg 720
caagtgatgc gggtctttac cgctgtgacg tcatgtacgg gattgaagac acacaagaca 780
cggtgtcact gactgtggat ggggttgtgt ttcactacag ggcggcaacc agcaggtaca 840
cactgaattt tgaggctgct cagaaggctt gtttggacgt tggggcagtc atagcaactc 900
cagagcagct ctttgctgcc tatgaagatg gatttgagca gtgtgacgca ggctggctgg 960
ctgatcagac tgtcagatat cccatccggg ctcccagagt aggctgttat ggagataaga 1020
tgggaaaggc aggagtcagg acttatggat tccgttctcc ccaggaaact tacgatgtgt 1080
attgttatgt ggatcatctg gatggtgatg tgttccacct cactgtcccc agtaaattca 1140
ccttcgagga ggctgcaaaa gagtgtgaaa accaggatgc caggctggca acagtggggg 1200
aactccaggc ggcatggagg aacggctttg accagtgcga ttacgggtgg ctgtcggatg 1260
ccagcgtgcg ccaccctgtg actgtggcca gggcccagtg tggaggtggt ctacttgggg 1320
tgagaaccct gtatcgtttt gagaaccaga caggcttccc tccccctgat agcagatttg 1380
atgcctactg ctttaaacga cctgatcgct gcaaaatgaa cccgtgcctt aacggaggca 1440
cctgttatcc tactgaaact tcctacgtat gcacctgtgt gccaggatac agcggagacc 1500
agtgtgaact tgattttgat gaatgtcact ctaatccctg tcgtaatgga gccacttgtg 1560
ttgatggttt taacacattc aggtgcctct gccttccaag ttatgttggt gcactttgtg 1620
agcaagatac cgagacatgt gactatggct ggcacaaatt ccaagggcag tgctacaaat 1680
actttgccca tcgacgcaca tgggatgcag ctgaacggga atgccgtctg cagggtgccc 1740
atctcacaag catcctgtct cacgaagaac aaatgtttgt taatcgtgtg ggccatgatt 1800
atcagtggat aggcctcaat gacaagatgt ttgagcatga cttccgttgg actgatggca 1860
gcacactgca atacgagaat tggagaccca accagccaga cagcttcttt tctgctggag 1920
aagactgtgt tgtaatcatt tggcatgaga atggccagtg gaatgatgtt ccctgcaatt 1980
accatctcac ctatacgtgc aagaaaggaa cagtcgcttg cggccagccc cctgttgtag 2040
aaaatgccaa gacctttgga aagatgaaac ctcgttatga aatcaactcc ctgattagat 2100
accactgcaa agatggtttc attcaacgtc accttccaac tatccggtgc ttaggaaatg 2160
gaagatgggc tatacctaaa attacctgca tgaacccatc tgcataccaa aggacttatt 2220
ctatgaaata ctttaaaaat tcctcatcag caaaggacaa ttcaataaat acatccaaac 2280
atgatcatcg ttggagccgg aggtggcagg agtcgaggcg ctgatcccta aaatggcgaa 2340
catgtgtttt catcatttca gccaaagtcc taacttcctg tgcctttcct atcacctcga 2400
gaagtaatta tcagttggtt tggatttttg gaccaccgtt cagtcatttt gggttgccgt 2460
gctcccaaaa cattttaaat gaaagtattg gcattcaaaa agacagcaga caaaatgaaa 2520
gaaaatgaga gcagaaagta agcatttcca gcctatctaa tttctttagt tttctatttg 2580
cctccagtgc agtccatttc ctaatgtata ccagcctact gtactattta aaatgctcaa 2640
tttcagcacc gatggccatg taaataagat gatttaatgt tgattttaat cctgtatata 2700
aaataaaaag tcacaatgag tttgggcata tttaatgatg attatggagc cttagaggtc 2760
tttaatcatt ggttcggctg cttttatgta gtttaggctg gaaatggttt cacttgctct 2820
ttgactgtca gcaagactga agatggcttt tcctggacag ctagaaaaca caaaatcttg 2880
taggtcattg cacctatctc agccataggt gcagtttgct tctacatgat gctaaaggct 2940
gcgaatggga tcctgatgga actaaggact ccaatgtcga actcttcttt gctgcattcc 3000
tttttcttca cttacaagaa aggcctgaat ggaggacttt tctgtaacca ggaacatttt 3060
ttaggggtca aagtgctaat aattaactca accaggtcta ctttttaatg gctttcataa 3120
cactaactca taaggttacc gatcaatgca tttcatacgg atatagacct agggctctgg 3180
agggtggggg attgttaaaa cacatgcaaa aaaaaaaaaa aaaaaaaaaa aagaaatttt 3240
gtatatataa ccattttaat cttttataaa gttttgaatg ttcatgtatg aatgctgcag 3300
ctgtgaagca tacataaata aatgaagtaa gccatactga tttaatttat tggatgttat 3360
tttccctaag acctgaaaat gaacatagta tgctagttat ttttcagtgt tagcctttta 3420
ctttcctcac acaatttgga atcatataat ataggtactt tgtccctgat taaataatgt 3480
gacggataga atgcatcaag tgtttattat gaaaagagtg gaaaagtata tagcttttag 3540
caaaaggtgt ttgcccattc taagaaatga gcgaatatat agaaatagtg tgggcatttc 3600
ttcctgttag gtggagtgta tgtgttgaca tttctcccca tctcttccca ctctgttttc 3660
tccccattat ttgaataaag tgactgctga agatgacttt gaatccttat ccacttaatt 3720
taatgtttaa agaaaaacct gtaatggaaa gtaagactcc ttccctaatt tcagtttaga 3780
gcaacttgaa gaagagtaga caaaaaataa aatgcacata gaaaaagaga aaaagggcac 3840
aaagggattg gcccaatatt gattcttttt ttataaaacc tcctttggct tagaaggaat 3900
gactctagct acaataatac acagtatgtt taagcaggtt cccttggttg ttgcattaaa 3960
tgtaatccac ctttaggtat tttagagcac agaacaacac tgtgttgatc tagtaggttt 4020
ctatttttcc tttctcttta caatgcacat aatactttcc tgtatttata tcataacgtg 4080
tatagtgtaa aatgtgaatg actttttttg tgaatgaaaa tctaaaatct ttgtaacttt 4140
ttatatctgc ttttgtttca ccaaagaaac ctaaaatcct tcttttacta cac 4193
<210> 169
<211> 3830
<212> DNA
<213>Artificial sequence (unknown)
<400> 169
cttcttcagc cactgcgagg tgaagcttta aacttcagac ttggaggtgg gctgtgtgca 60
gtaaactgga atgctctccc tcgctcactc ctcagtgtag gagtgatctg aagcaggaca 120
agctcagcct gcagctgccg tgggctttgt gtggactgga cgcagagctt gggagacggg 180
ggagggctat tactccaatt cactgtcaat ggaattacag ctatagcggc agtgtatata 240
ggattgcttt ttctcgtctt cctgggttct gaagtaacgg aagctacctt gtataaagac 300
ctcaacactg ctgaccatga tcagcgcagc ctggagcatc ttcctcatcg ggactaaaat 360
tgggctgttc cttcaagtag cacctctatc agttatggct aaatcctgtc catctgtgtg 420
tcgctgcgat gcgggtttca tttactgtaa tgatcgcttt ctgacatcca ttccaacagg 480
aataccagag gatgctacaa ctctctacct tcagaacaac caaataaata atgctgggat 540
tccttcagat ttgaaaaact tgctgaaagt agaaagaata tacctatacc acaacagttt 600
agatgaattt cctaccaacc tcccaaagta tgtaaaagag ttacatttgc aagaaaataa 660
cataaggact atcacttatg attcactttc aaaaattccc tatctggaag aattacattt 720
agatgacaac tctgtctctg cagttagcat agaagaggga gcattccgag acagcaacta 780
tctccgactg cttttcctgt cccgtaatca ccttagcaca attccctggg gtttgcccag 840
gactatagaa gaactacgct tggatgataa tcgcatatcc actatttcat caccatctct 900
tcaaggtctc actagtctaa aacgcctggt tctagatgga aacctgttga acaatcatgg 960
tttaggtgac aaagttttct tcaacctagt taatttgaca gagctgtccc tggtgcggaa 1020
ttccctgact gctgcaccag taaaccttcc aggcacaaac ctgaggaagc tttatcttca 1080
agataaccac atcaatcggg tgcccccaaa tgctttttct tatctaaggc agctctatcg 1140
actggatatg tccaataata acctaagtaa tttacctcag ggtatctttg atgatttgga 1200
caatataaca caactgattc ttcgcaacaa tccctggtat tgcgggtgca agatgaaatg 1260
ggtacgtgac tggttacaat cactacctgt gaaggtcaac gtgcgtgggc tcatgtgcca 1320
agccccagaa aaggttcgtg ggatggctat taaggatctc aatgcagaac tgtttgattg 1380
taaggacagt gggattgtaa gcaccattca gataaccact gcaataccca acacagtgta 1440
tcctgcccaa ggacagtggc cagctccagt gaccaaacag ccagatatta agaaccccaa 1500
gctcactaag gatcaccaaa ccacagggag tccctcaaga aaaacaatta caattactgt 1560
gaagtctgtc acctctgata ccattcatat ctcttggaaa cttgctctac ctatgactgc 1620
tttgagactc agctggctta aactgggcca tagcccggca tttggatcta taacagaaac 1680
aattgtaaca ggggaacgca gtgagtactt ggtcacagcc ctggagcctg attcacccta 1740
taaagtatgc atggttccca tggaaaccag caacctctac ctatttgatg aaactcctgt 1800
ttgtattgag actgaaactg caccccttcg aatgtacaac cctacaacca ccctcaatcg 1860
agagcaagag aaagaacctt acaaaaaccc caatttacct ttggctgcca tcattggtgg 1920
ggctgtggcc ctggttacca ttgcccttct tgctttagtg tgttggtatg ttcataggaa 1980
tggatcgctc ttctcaagga actgtgcata tagcaaaggg aggagaagaa aggatgacta 2040
tgcagaagct ggcactaaga aggacaactc tatcctggaa atcagggaaa cttcttttca 2100
gatgttacca ataagcaatg aacccatctc gaaggaggag tttgtaatac acaccatatt 2160
tcctcctaat ggaatgaatc tgtacaaaaa caatcacagt gaaagcagta gtaaccgaag 2220
ctacagagac agtggtattc cagactcaga tcactcacac tcatgatgct gaaggactca 2280
cagcagactt gtgttttggg ttttttaaac ctaagggagg tgatggtagg aaccctgttc 2340
tactgcaaaa cactggaaaa agagactgaa aaaaagcaat gtactgtaca tttgccatat 2400
aatttatatt taagaacttt ttattaaaag tttcaaattt caggttactg ctgcgattga 2460
tgtagtggag atgcctgaac acaattctat attttagtat tttttagtaa tttgtactgt 2520
attttccttg caaatattgg agttataaac catttacttt gtgttctact gagtaagatg 2580
acttgttgac tgtgaaagtg aattttcttg ctgtgtcgaa caatcaggac tgcattcata 2640
tgagatcctt gtagtataag cacaggccat ttttcacttt ggtattaata aaatgtaaaa 2700
aaaaaaaact ggctgaatgg ctgaatgaga taaaatttaa ttttaaaaaa tggttatgaa 2760
ataatgttcc aattattaaa tttgtattat cccagtggta ttcaataaat caaaatgtgt 2820
gaagtaatgg gcaatatcaa acttcctgca tatctccatt tttgctctag gcaaattaat 2880
tatccttaaa aaagttaagc atatcttctg aactgaatac atcagctggc ataaaaggag 2940
catgaagtct gttaaagcca ttgtcagcaa agctttgaaa ataaaggact tcacaaaaac 3000
ggtaatgtaa atgtgcttcc aagttggggg gaaaatgtgt acttaggaaa acatggaaac 3060
ttagacttgt atagtgtaat gaacacaaat accaaaactg cattttggtt ttgcctatac 3120
catcctgatt tttgaaaagt gaattataaa cacaaaattg ttagtgttta tgatgttttt 3180
atcataaagg atgtcagaga aactttatgc atattaaaaa tgtaatgtaa ttataagcga 3240
ttcccctcaa caatccagag aaagtagttc tttaaataag agataattta aagaaaaata 3300
aatactagac atcaaattta gatctggttt atgtcaaagg ttttaacact gtacataaat 3360
gttcaattta cttttacaaa gatcaagaat actgcccatt actgtcacaa ttttccagat 3420
attatataat gaactcgtaa tgtaacattt ccttctagct tcctactgaa ttgtgagctg 3480
ttacttgttg aaaaaccata tcacttttct gttgccatga tttttttttt ttcaacaaaa 3540
aaccaaagtg cattgtacgc cctttggcca gtcttgtatg tgccttgatc caacgctaca 3600
tgtattcagc ttttaaaact ccacaaattt ttcatactcc ttaaatatga aaaattatgg 3660
tcttattgct gaataaaact tttaaaaagt acagaataat tgtgcttgct ttttcaggat 3720
tgtgttacta tcactaagta gcaaattgcc cagcacatta gtcctaaacg tcccatgtat 3780
ttttctaggc ataaaaataa aagttggcta aaaattttaa aaaatcaaca 3830
<210> 170
<211> 1153
<212> DNA
<213>Artificial sequence (unknown)
<400> 170
gaaaacacca aatcaaccat aggtccaaga acaattgtct ctggacggca gctatgcgac 60
tcaccgtgct gtgtgctgtg tgcctgctgc ctggcagcct ggccctgccg ctgcctcagg 120
aggcgggagg catgagtgag ctacagtggg aacaggctca ggactatctc aagagatttt 180
atctctatga ctcagaaaca aaaaatgcca acagtttaga agccaaactc aaggagatgc 240
aaaaattctt tggcctacct ataactggaa tgttaaactc ccgcgtcata gaaataatgc 300
agaagcccag atgtggagtg ccagatgttg cagaatactc actatttcca aatagcccaa 360
aatggacttc caaagtggtc acctacagga tcgtatcata tactcgagac ttaccgcata 420
ttacagtgga tcgattagtg tcaaaggctt taaacatgtg gggcaaagag atccccctgc 480
atttcaggaa agttgtatgg ggaactgctg acatcatgat tggctttgcg cgaggagctc 540
atggggactc ctacccattt gatgggccag gaaacacgct ggctcatgcc tttgcgcctg 600
ggacaggtct cggaggagat gctcacttcg atgaggatga acgctggacg gatggtagca 660
gtctagggat taacttcctg tatgctgcaa ctcatgaact tggccattct ttgggtatgg 720
gacattcctc tgatcctaat gcagtgatgt atccaaccta tggaaatgga gatccccaaa 780
attttaaact ttcccaggat gatattaaag gcattcagaa actatatgga aagagaagta 840
attcaagaaa gaaatagaaa cttcaggcag aacatccatt cattcattca ttggattgta 900
tatcattgtt gcacaatcag aattgataag cactgttcct ccactccatt tagcaattat 960
gtcacccttt tttattgcag ttggtttttg aatgtctttc actcctttta aggataaact 1020
cctttatggt gtgactgtgt cttattcatc tatacttgca gtgggtagat gtcaataaat 1080
gttacataca caaataaata aaatgtttat tccatggtaa atttaaaaaa aaaaaaaaaa 1140
aaaaaaaaaa aaa 1153
<210> 171
<211> 1227
<212> DNA
<213>Artificial sequence (unknown)
<400> 171
acttgcctca tgtcttagaa tccagtaggt ggccccttgg ccatgaaatg tgtgggagtg 60
gcttttccct aacttgactc ttctttcagt gggagagaac tattgagagg aacaaagagc 120
ttataaatac attaggacct ggaattcagt tgtcgagcca ggacggtgac agcgtttaac 180
aaagcttaga gaaacctcca ggagactgct atcatggcag agaagcccaa gctccactac 240
ttcaatgcac ggggcagaat ggagtccacc cggtggctcc tggctgcagc tggagtagag 300
tttgaagaga aatttataaa atctgcagaa gatttggaca agttaagaaa tggattgata 360
tgtatataga aggtatagca gatttgggtg aaatgatcct ccttctgccc gtatgtccac 420
ctgaggaaaa agatgccaag cttgccttga tcaaagagaa aataaaaaat cgctacttcc 480
ctgcctttga aaaagtctta aagagccatg gacaagacta ccttgttggc aacaagctga 540
gccgggctga cattcatctg gtggaacttc tctactacgt cgaggagctt gactccagtc 600
ttatctccag cttccctctg ctgaaggccc tgaaaaccag aatcagcaac ctgcccacag 660
tgaagaagtt tctacagcct ggcagcccaa ggaagcctcc catggatgag aaatctttag 720
aagaagcaag gaagattttc aggttttaat aacgcagtca tggaggccaa gaacttgcaa 780
taccaatgtt ctaaagtttt gcaacaataa agtactttac ctaagtgttg attgtgcctg 840
ttgtgaagct aatgaactct ttcaaattat atgctaatta aataatacaa ctcctattcg 900
ctgacttagt taaaattgat ttgttttcat taggatctga tgtgaattca gatttccaat 960
cttctcctag ccaaccattt tcctggaatt aaaaattcag taaaaaagga aactatagat 1020
tatgtggttt gtttgacttt tccaagaatt gtcccgtaac atacaatttg tcatacaatc 1080
tattaaaatg tcaatgtaga aatgcacttc tgacattttc aggtatgcac aggagaagag 1140
ttaccatcct ggataatggc ataaagacat tttcttcttt tcctggacag tcattttatt 1200
tctgataaaa gcgttctttc ttatgca 1227
<210> 172
<211> 964
<212> DNA
<213>Artificial sequence (unknown)
<400> 172
aggaggagga ggcaccaaac ggcctgggtg gatagaaggg ggacaaggag gcacacccag 60
gccggcaaag agcagctcag tgagtactgg gtatgtgtca cattgccaaa tcccggatca 120
caagtctcca tgaactgctg gtgagctagg ataataaaac ccctgacatc accattccag 180
aagcttcaca agactgcata tataaggggc tggctgtagc tgcagctgaa ggagctgacc 240
agccagctga cccctcacac tcacctagcc accatggaca tcgccatcca ccacccctgg 300
atccgccgcc ccttctttcc tttccactcc cccagccgcc tctttgacca gttcttcgga 360
gagcacctgt tggagtctga tcttttcccg acgtctactt ccctgagtcc cttctacctt 420
cggccaccct ccttcctgcg ggcacccagc tggtttgaca ctggactctc agagatgcgc 480
ctggagaagg acaggttctc tgtcaacctg gatgtgaagc acttctcccc agaggaactc 540
aaagttaagg tgttgggaga tgtgattgag gtgcatggaa aacatgaaga gcgccaggat 600
gaacatggtt tcatctccag ggagttccac aggaaatacc ggatcccagc tgatgtagac 660
cctctcacca ttacttcatc cctgtcatct gatggggtcc tcactgtgaa tggaccaagg 720
aaacaggtct ctggccctga gcgcaccatt cccatcaccc gtgaagagaa gcctgctgtc 780
accgcagccc ccaagaaata gatgcccttt cttgaattgc attttttaaa acaagaaagt 840
ttccccacca gtgaatgaaa gtcttgtgac tagtgctgaa gcttattaat gctaagggca 900
ggcccaaatt atcaagctaa taaaatatca ttcagcaaca gataaaaaaa aaaaaaaaaa 960
aaaa 964
<210> 173
<211> 4134
<212> DNA
<213>Artificial sequence (unknown)
<400> 173
cagctggggg taaggggggc ggattattca tataattgtt ataccagacg gtcgcaggct 60
tagtccaatt gcagagaact cgcttcccag gcttctgaga gtcccggaag tgcctaaacc 120
tgtctaatcg acggggcttg ggtggcccgt cgctccctgg cttcttccct ttacccaggg 180
cgggcagcga agtggtgcct cctgcgtccc ccacaccctc cctcagcccc tcccctccgg 240
cccgtcctgg gcaggtgacc tggagcatcc ggcaggctgc cctggcctcc tgcgtcagga 300
caacgcccac gaggggcgtt actgtgcgga gatgcaccac gcaagagaca ccctttgtaa 360
ctctcttctc ctccctagtg cgaggttaaa accttcagcc ccacgtgctg tttgcaaacc 420
tgcctgtacc tgaggcccta aaaagccaga gacctcactc ccggggagcc agcatgtcca 480
ctgcggtcct ggaaaaccca ggcttgggca ggaaactctc tgactttgga caggaaacaa 540
gctatattga agacaactgc aatcaaaatg gtgccatatc actgatcttc tcactcaaag 600
aagaagttgg tgcattggcc aaagtattgc gcttatttga ggagaatgat gtaaacctga 660
cccacattga atctagacct tctcgtttaa agaaagatga gtatgaattt ttcacccatt 720
tggataaacg tagcctgcct gctctgacaa acatcatcaa gatcttgagg catgacattg 780
gtgccactgt ccatgagctt tcacgagata agaagaaaga cacagtgccc tggttcccaa 840
gaaccattca agagctggac agatttgcca atcagattct cagctatgga gcggaactgg 900
atgctgacca ccctggtttt aaagatcctg tgtaccgtgc aagacggaag cagtttgctg 960
acattgccta caactaccgc catgggcagc ccatccctcg agtggaatac atggaggaag 1020
aaaagaaaac atggggcaca gtgttcaaga ctctgaagtc cttgtataaa acccatgctt 1080
gctatgagta caatcacatt tttccacttc ttgaaaagta ctgtggcttc catgaagata 1140
acattcccca gctggaagac gtttctcagt tcctgcagac ttgcactggt ttccgcctcc 1200
gacctgtggc tggcctgctt tcctctcggg atttcttggg tggcctggcc ttccgagtct 1260
tccactgcac acagtacatc agacatggat ccaagcccat gtataccccc gaacctgaca 1320
tctgccatga gctgttggga catgtgccct tgttttcaga tcgcagcttt gcccagtttt 1380
cccaggaaat tggccttgcc tctctgggtg cacctgatga atacattgaa aagctcgcca 1440
caatttactg gtttactgtg gagtttgggc tctgcaaaca aggagactcc ataaaggcat 1500
atggtgctgg gctcctgtca tcctttggtg aattacagta ctgcttatca gagaagccaa 1560
agcttctccc cctggagctg gagaagacag ccatccaaaa ttacactgtc acggagttcc 1620
agcccctcta ttacgtggca gagagtttta atgatgccaa ggagaaagta aggaactttg 1680
ctgccacaat acctcggccc ttctcagttc gctacgaccc atacacccaa aggattgagg 1740
tcttggacaa tacccagcag cttaagattt tggctgattc cattaacagt gaaattggaa 1800
tcctttgcag tgccctccag aaaataaagt aaagccatgg acagaatgtg gtctgtcagc 1860
tgtgaatctg ttgatggaga tccaactatt tctttcatca gaaaaagtcc gaaaagcaaa 1920
ccttaatttg aaataacagc cttaaatcct ttacaagatg gagaaacaac aaataagtca 1980
aaataatctg aaatgacagg atatgagtac atactcaaga gcataatggt aaatcttttg 2040
gggtcatctt tgatttagag atgataatcc catactctca attgagttaa atcagtaatc 2100
tgtcgcattt catcaagatt aattaaaatt tgggacctgc ttcattcaag cttcatatat 2160
gctttgcaga gaactcataa aggagcatat aaggctaaat gtaaaacaca agactgtcat 2220
tagaattgaa ttattgggct taatataaat cgtaacctat gaagtttatt ttctatttta 2280
gttaactatg attccaatta ctactttgtt attgtaccta agtaaatttt ctttaagtca 2340
gaagcccatt aaaatagtta caagcattga acttctttag tattatatta atataaaaac 2400
atttttgtat gttttattgt aatcataaat actgctgtat aaggtaataa aactctgcac 2460
ctaatcccca taacttccag tatcattttc caattaatta tcaagtctgt tttgggaaac 2520
actttgagga catttatgat gcagcagatg ttgactaaag gcttggttgg tagatattca 2580
ggaaatgttc actgaataaa taagtaaata cattattgaa aagcaaatct gtataaatgt 2640
gaaattttta tttgtattag taataaaaca ttagtagttt aaacaatttc actgtttcag 2700
ttatttcctg gaatgaaata ttcctctcac tgccttagaa atacattagc tagatagttt 2760
tgtaacatga gaaaatggcc agaggctcat atctccaacc ctttgcaggg gctccttgtg 2820
acactcaaag tcatgcctgg acagtcaacg gactttgact tttgttgatt gtgtgtttgc 2880
catgaaaaca tgaatatctg agaagcagtg gggagaaaaa aaacaatatc tttgtagcta 2940
tgatttgaaa ttctcatact actttacatt ttattttgga aatagttaag tcttaaagaa 3000
tttgcatagt gtttctttga gtttagttct cagaacagct gtagtatcat caacagcaaa 3060
ttctgggtac cttcccagct ccacccaatt tgaatctctg aagataaggc ccagagacct 3120
gtatttttaa gtaccccatt tttttaatta ttcatagcca aattctatca ggtacattca 3180
gtttgagaaa acctgatttg tggtggtcag tctgccactg ccaatgatgt caatgtggat 3240
aagctgtttc ccttctttag acctcagtgt cactctaaca atgagggagt taaactttat 3300
aaaccaaggt ccattgcagc cttgaaatat gattcaagtg ttcatatgtg tctttatata 3360
gctatgcctg atccactgat ggggtgttac aatacctgct tatatatgcc agctgggagg 3420
aaagaggaat ttactgaatg tgtctgaagt ttcattgttt tgaagttgga attttatgcc 3480
tgtatctatg tttatgcctt tgtaaaaccc actgatttta aaagtgaaaa aggacttttt 3540
tctctgcttt tactctaaac accaaacaat ccctgcaaag ggattattct gatgtttctt 3600
catttcacat gaaaagttaa ttattgactc tggaacttaa atattagata atatttttga 3660
caatattgaa gagtgagttt tagtccagta aagatgtttt aatgagcttg aaggtaaagt 3720
ttcggttaag ttatgatttt cacaggaagt tacatactga atgaaagata atatttgtat 3780
ttttggtaat gtgctactca gttcttagct cttttttatc cagatataaa agcccagtct 3840
atagctatgg gatttaataa atttccaata tgtaagtgtt tttatttgtt taatttctag 3900
taaatgagca atattttaga aacagtatca gtctttactg acagatgatc ttgctgagta 3960
caatcaaaat aaatacataa aaaattctaa gcatgtggca ttgatgttta ataagtttct 4020
gaaagtagga atctgaattt taactgtagg tttctaagtt atataattta gttgtgtttc 4080
aaaaaatcca ccaataaaat gtcagcttta taaaaacaga aaaaaaaaaa aaaa 4134
<210> 174
<211> 1608
<212> DNA
<213>Artificial sequence (unknown)
<400> 174
atcattaacc tcctggtgca agtggcgcgg cctgtgccct ttataaggtg cgcgctgtgt 60
ccagcgagca tcggccaccg ccatcccatc cagcgagcat ctgccgccgc gccgccgcca 120
ccctcccaga gagcactggc caccgctcca ccatcacttg cccagagttt gggccaccgc 180
ccgccgccac cagcccagag agcatcggcc cctgtctgct gctcgcgcct ggagatgtca 240
gaggtccccg ttgctcgcgt ctggctggta ctgctcctgc tgactgtcca ggtcggcgtg 300
acagccggcg ctccgtggca gtgcgcgccc tgctccgccg agaagctcgc gctctgcccg 360
ccggtgtccg cctcgtgctc ggaggtcacc cggtccgccg gctgcggctg ttgcccgatg 420
tgcgccctgc ctctgggcgc cgcgtgcggc gtggcgactg cacgctgcgc ccggggactc 480
agttgccgcg cgctgccggg ggagcagcaa cctctgcacg ccctcacccg cggccaaggc 540
gcctgcgtgc aggagtctga cgcctccgct ccccatgctg cagaggcagg gagccctgaa 600
agcccagaga gcacggagat aactgaggag gagctcctgg ataatttcca tctgatggcc 660
ccttctgaag aggatcattc catcctttgg gacgccatca gtacctatga tggctcgaag 720
gctctccatg tcaccaacat caaaaaatgg aaggagccct gccgaataga actctacaga 780
gtcgtagaga gtttagccaa ggcacaggag acatcaggag aagaaatttc caaattttac 840
ctgccaaact gcaacaagaa tggattttat cacagcagac agtgtgagac atccatggat 900
ggagaggcgg gactctgctg gtgcgtctac ccttggaatg ggaagaggat ccctgggtct 960
ccagagatca ggggagaccc caactgccag atatatttta atgtacaaaa ctgaaaccag 1020
atgaaataat gttctgtcac gtgaaatatt taagtatata gtatatttat actctagaac 1080
atgcacattt atatatatat gtatatgtat atatatatag taactacttt ttatactcca 1140
tacataactt gatatagaaa gctgtttatt tattcactgt aagtttattt tttctacaca 1200
gtaaaaactt gtactatgtt aataacttgt cctatgtcaa tttgtatatc atgaaacact 1260
tctcatcata ttgtatgtaa gtaattgcat ttctgctctt ccaaagctcc tgcgtctgtt 1320
tttaaagagc atggaaaaat actgcctaga aaatgcaaaa tgaaataaga gagagtagtt 1380
tttcagctag tttgaaggag gacggttaac ttgtatattc caccattcac atttgatgta 1440
catgtgtagg gaaagttaaa agtgttgatt acataatcaa agctacctgt ggtgatgttg 1500
ccacctgtta aaatgtacac tggatatgtt gttaaacacg tgtctataat ggaaacattt 1560
acaataaata ttctgcatgg aaatactgtt aaaaaaaaaa aaaaaaaa 1608
<210> 175
<211> 3152
<212> DNA
<213>Artificial sequence (unknown)
<400> 175
ataacgctac ctgccgagca agccgagtgg agggaggcaa aggccaggct gaggatcagg 60
gtggcccggg tggcagcggg gaggcgctgc atgctggagg ctgtgctgag tgcccggtgc 120
aggtgagccg gtcctgcgga gttgtgccga gtgcctgctg cagtctcatt tccagttcct 180
ccatgacgtg gcaagtgaag acaggaatga aaggaatgta aagcagcttt tctctgaaga 240
gaagaagaga gagagacaca gccaagaccg aggctgggcc aagatggtgt ctgtgtttcg 300
aagcgaggag atgtgtttgt cacaactgtt tctccaggtg gaagctgcat attgctgtgt 360
ggctgagctc ggagagctcg gattggttca gttcaaagat ttaaatatga atgtgaacag 420
ctttcaaagg aaatttgtga atgaagtcag aaggtgtgaa tcactggaga gaatcctccg 480
ttttctggaa gacgagatgc aaaatgagat tgtagttcag ttgctcgaga aaagcccact 540
gaccccgctc ccacgggaaa tgattaccct ggagactgtt ctagaaaaac tggaaggaga 600
gttacaggaa gccaaccaga accagcaggc cttgaaacaa agcttcctag aactgacaga 660
actgaaatac ctcctgaaga aaacccaaga cttctttgag acggaaacca atttagctga 720
tgatttcttt actgaggaca cttctggcct cctggagttg aaagcagtgc ctgcatatat 780
gaccggaaag ttggggttca tagccggtgt gatcaacagg gagaggatgg cttcctttga 840
gcggttactg tggcgaatct gccgaggaaa cgtgtacttg aagttcagtg agatggacgc 900
ccctctggag gatcctgtga cgaaagaaga aattcagaag aacatattca tcatatttta 960
ccaaggagag cagctcaggc agaaaatcaa gaagatctgt gatgggtttc gagccactgt 1020
ctacccttgc ccagagcctg cggtggagcg cagagagatg ttggagagcg tcaatgtgag 1080
gctggaagat ttaatcaccg tcataacaca aacagagtct caccgccagc gcctgctgca 1140
ggaagccgct gccaactggc actcctggct catcaaggtg cagaagatga aagctgtcta 1200
ccacatcctg aacatgtgca acatcgacgt cacccagcag tgtgtcatcg ccgagatctg 1260
gttcccggtg gcagatgcca cacgtatcaa gagggcactg gagcaaggca tggaactaag 1320
tggctcctcc atggccccca tcatgaccac agtgcaatct aaaacagccc ctcccacatt 1380
taacaggacc aataaattca cagctggctt ccagaatatt gttgatgcct atggtgtcgg 1440
cagctaccgg gagataaacc cagcccccta caccatcatc actttcccct tcctgttcgc 1500
tgtgatgttt ggagactgtg gtcatggaac cgtgatgctc ctggctgcac tttggatgat 1560
tctgaatgag agacgcttgc tctcccagaa gacagacaat gagatttgga acaccttctt 1620
ccacgggcgc tatctgatcc tacttatggg catcttctcc atctacacgg gtttgatcta 1680
caatgactgc ttctccaagt ccttgaacat ctttggctct tcttggagtg tccaacccat 1740
gttcagaaac ggcacatgga atactcatgt aatggaggaa agtctatatc tgcagctgga 1800
cccagccata ccaggagtgt attttggaaa tccatacccg tttgggattg atccgatttg 1860
gaacttggct tcaaacaaac tcacatttct gaactcgtat aaaatgaaga tgtcggtgat 1920
cctgggaatt gtccagatgg ttttcggtgt catcctcagc cttttcaatc acatatactt 1980
cagaagaact ctcaacatca ttctgcaatt tatccctgag atgattttta tcctgtgtct 2040
gtttggatac ctggttttca tgatcatttt caaatggtgc tgctttgacg tccatgtatc 2100
tcagcacgcc cccagcatcc tcatccactt catcaacatg tttctgttta actacagtga 2160
ctcttccaac gcacccctct acaaacatca gcaagaagtc caaagtttct ttgtggttat 2220
ggctttgatt tctgtgccgt ggatgcttct gattaagccg tttattctta gagccagtca 2280
tcggaaatcc cagctgcagg catccaggat ccaagaagat gccactgaga acattgaagg 2340
tgatagctcc agcccttcta gccgttctgg ccagaggact tctgcagata cccacggggc 2400
tctggacgac catggagaag agttcaactt tggagacgtc tttgtccacc aagccatcca 2460
caccatcgag tactgcctgg gctgcatttc aaacacagcc tcctacctgc ggctctgggc 2520
cctcagcctg gctcatgcac aactgtctga agtgctctgg actatggtga tgaacagcgg 2580
ccttcagacg cgaggctggg gaggaatcgt cggggttttt attatttttg ccgtatttgc 2640
tgtcctgaca gtagccatcc ttctgatcat ggagggcctc tctgctttcc tgcacgccct 2700
gcgactgcac tgggttgagt tccagaacaa gttctatgtc ggggatggtt acaagttttc 2760
tccattctcc tttaaacaca tcctggatgg cacagccgag gagtaggctg agggctgcac 2820
ctcccacggt ggtcaccatg ccaatgaagg aagttcagtc ttgtctttga tatcagcccc 2880
tgcaaggcgc tcaatgggaa ggttgttctt ggctcacctg aagcatgaaa ctgtgtatta 2940
tttggacgtc agcctgtgga tttgatacga cttaaccacg tcagaggaag gactttggca 3000
agtgatattg tcttcatgtg gggtattaat tctcaaataa taaagtaatt gacaaatgag 3060
gggagaatgc taaacagatg tcttcttgca atattttaaa tattgtattt gagaaaataa 3120
acatctgagt cattcaaaaa aaaaaaaaaa aa 3152
<210> 176
<211> 2426
<212> DNA
<213>Artificial sequence (unknown)
<400> 176
atctgtctta tttggcagct gctgcctcac ccacagcttt tgatatctag gaggactctt 60
ctctcccaaa ctacctgtca ccatggccca ccgatttcca gccctcaccc aggagcagaa 120
gaaggagctc tcagaaattg cccagagcat tgttgccaat ggaaagggga tcctggctgc 180
agatgaatct gtaggtacca tggggaaccg cctgcagagg atcaaggtgg aaaacactga 240
agagaaccgc cggcagttcc gagaaatcct cttctctgtg gacagttcca tcaaccagag 300
catcgggggt gtgatccttt tccacgagac cctctaccag aaggacagcc agggaaagct 360
gttcagaaac atcctcaagg aaaaggggat cgtggtggga atcaagttag accaaggagg 420
tgctcctctt gcaggaacaa acaaagaaac caccattcaa gggcttgatg gcctctcaga 480
gcgctgtgct cagtacaaga aagatggtgt tgactttggg aagtggcgtg ctgtgctgag 540
gattgccgac cagtgtccat ccagcctcgc tatccaggaa aacgccaacg ccctggctcg 600
ctacgccagc atctgtcagc agaatggact ggtacctatt gttgaaccag aggtaattcc 660
tgatggagac catgacctgg aacactgcca gtatgttact gagaaggtcc tggctgctgt 720
ctacaaggcc ctgaatgacc atcatgttta cctggagggc accctgctaa agcccaacat 780
ggtgactgct ggacatgcct gcaccaagaa gtatactcca gaacaagtag ctatggccac 840
cgtaacagct ctccaccgta ctgttcctgc agctgttcct ggcatctgct ttttgtctgg 900
tggcatgagt gaagaggatg ccactctcaa cctcaatgct atcaaccttt gccctctacc 960
aaagccctgg aaactaagtt tctcttatgg acgggccctg caggccagtg cactggctgc 1020
ctggggtggc aaggctgcaa acaaggaggc aacccaggag gcttttatga agcgggccat 1080
ggctaactgc caggcggcca aaggacagta tgttcacacg ggttcttctg gggctgcttc 1140
cacccagtcg ctcttcacag cctgctatac ctactagggt ccaatgcccg ccagcctagc 1200
tccagtgctt ctagtaggag ggctgaaagg gagcaacttt tcctccaatc ctggaaattc 1260
gacacaatta gatttgaact gctggaaata caacacatgt taaatcttaa gtacaagggg 1320
gaaaaaataa atcagttatt gaaacataaa aatgaatacc aaggacctga tcaaatttca 1380
cacagcagtt tccttgcaac actttcagct ccccatgctc cagaataccc acccaagaaa 1440
ataataggct ttaaaacaat atcggctcct catccaaaga acaactgctg attgaaacac 1500
ctcattagct gagtgtagag aagtgcatct tatgaaacag tcttagcagt ggtaggttgg 1560
gaaggagata gctgcaacca aaaaagaaat aaatattcta taaaccttca gctgctatcg 1620
ggtttcactt ttctgctctt gctgtccaaa gactcagtgt atttcattac ttttgactct 1680
actagacatg actgggtttc aacagtaaag gtcttcaact cttgctagtc attggaatca 1740
agccgcaaaa ttttaaaaac tgagatgctc aggccacacc ccagctcaat taaatcagaa 1800
accctagact tgggatcctc taactattag atttcttaaa gctccctcag taattccaat 1860
gtacagtcaa gtttgagaac taccaatcta aatttcaagt ttgagggtat ttgaaaatta 1920
aagccattca caatacgaag ccagctaaaa atgtagaatg attttgagca acttgtggag 1980
tataataaga gaattaatgt gacttcaatg cttggagcat tcttgttcaa gtggcccagg 2040
tttggtgaaa caggactacc ttgtcatctg cacgtccagg catatttcgt agttttgcag 2100
taaataatat tcacataatg atactgtatt gactttcaat tttcagaatt aacctatagt 2160
tacagcactt aagacaacca gagttataaa agagaattta aatattataa ctttggacaa 2220
tataaaagtg atgatttaac tgacagaagc taggaaatat aagggggagg agaagtggaa 2280
gaaagcaaag agagtcagga atactactta aaactgatgg gttaagaaat agtgctttaa 2340
ttctatttaa gtaataaaag aaatggatgt aaatcataaa aatatatatc taaaattaaa 2400
atattgatgg tagtatgcta aatttc 2426

Claims (9)

1. one group of gene for being used for clear-cell carcinoma molecule parting, it is characterised in that including following 44 genes：RHCG genes, RNF128 genes, TMEM255A genes, PCP4 genes, DHRS2 genes, CLDN8 genes, AQP6 genes, SLC18A2 genes, KRT7 genes, SERPINA5 genes, SFTPB genes, DEFB1 genes, MAL genes, ANGPTL4 genes, LCN2 genes, PLIN2 Gene, ZNF395 genes, TACSTD2 genes, NDUFA4L2 genes, NNMT genes, HILPDA genes, UMOD genes, SLC12A1 Gene, CALB1 genes, C7 genes, S100A2 genes, ASS1 genes, MT1G genes, ABCA8 genes, FOSB genes, MAOB bases Cause, STAP1 genes, TFPI2 genes, AKR1C2 genes, IGFBP6 genes, VCAN genes, FLRT3 genes, MMP7 genes, GSTA1 genes, CRYAB genes, PAH genes, IGFBP1 genes, ATP6V0A4 genes, ALDOB genes.
2. gene as claimed in claim 1, it is characterised in that the clear-cell carcinoma molecule parting is oxyphilic adenoma, thoroughly Clear cell carcinoma, papillary cell carcinoma and chromophobe cell tumor.
3. gene as claimed in claim 1, it is characterised in that the transcript sequence of 44 genes respectively is：SEQ ID NO.133-SEQ ID NO.176。
4. one group of gene for being used for clear-cell carcinoma molecule parting as described in claim any one of 1-3 is used for nephrocyte in preparation Application in the kit of cancer molecule parting.
A kind of 5. kit for clear-cell carcinoma molecule parting, it is characterised in that the kit includes following biomarker, The biomarker is used for appointing in the gene of clear-cell carcinoma molecule parting selected from one group described in claim any one of 1-3 Meaning is one or more.
6. kit as claimed in claim 5, it is characterised in that the biomarker is that nucleic acid, oligonucleotide chain or PCR draw Thing group.
7. kit as claimed in claim 6, it is characterised in that the PCR primer group includes：
RHCG genes：Forward primer is as shown in SEQ ID NO.1, and reverse primer is as shown in SEQ ID NO.2；
RNF128 genes：Forward primer is as shown in SEQ ID NO.3, and reverse primer is as shown in SEQ ID NO.4；
TMEM255A genes：Forward primer is as shown in SEQ ID NO.5, and reverse primer is as shown in SEQ ID NO.6；
PCP4 genes：Forward primer is as shown in SEQ ID NO.7, and reverse primer is as shown in SEQ ID NO.8；
DHRS2 genes：Forward primer is as shown in SEQ ID NO.9, and reverse primer is as shown in SEQ ID NO.10；
CLDN8 genes：Forward primer is as shown in SEQ ID NO.11, and reverse primer is as shown in SEQ ID NO.12；
AQP6 genes：Forward primer is as shown in SEQ ID NO.13, and reverse primer is as shown in SEQ ID NO.14；
SLC18A2 genes：Forward primer is as shown in SEQ ID NO.15, and reverse primer is as shown in SEQ ID NO.16；
KRT7 genes：Forward primer is as shown in SEQ ID NO.17, and reverse primer is as shown in SEQ ID NO.18；
SERPINA5 genes：Forward primer is as shown in SEQ ID NO.19, and reverse primer is as shown in SEQ ID NO.20；
SFTPB genes：Forward primer is as shown in SEQ ID NO.21, and reverse primer is as shown in SEQ ID NO.22；
DEFB1 genes：Forward primer is as shown in SEQ ID NO.23, and reverse primer is as shown in SEQ ID NO.24；
MAL genes：Forward primer is as shown in SEQ ID NO.25, and reverse primer is as shown in SEQ ID NO.26；
ANGPTL4 genes：Forward primer is as shown in SEQ ID NO.27, and reverse primer is as shown in SEQ ID NO.28；
LCN2 genes：Forward primer is as shown in SEQ ID NO.29, and reverse primer is as shown in SEQ ID NO.30；
PLIN2 genes：Forward primer is as shown in SEQ ID NO.31, and reverse primer is as shown in SEQ ID NO.32；
ZNF395 genes：Forward primer is as shown in SEQ ID NO.33, and reverse primer is as shown in SEQ ID NO.34；
TACSTD2 genes：Forward primer is as shown in SEQ ID NO.35, and reverse primer is as shown in SEQ ID NO.36；
NDUFA4L2 genes：Forward primer is as shown in SEQ ID NO.37, and reverse primer is as shown in SEQ ID NO.38；
NNMT genes：Forward primer is as shown in SEQ ID NO.39, and reverse primer is as shown in SEQ ID NO.40；
HILPDA genes：Forward primer is as shown in SEQ ID NO.41, and reverse primer is as shown in SEQ ID NO.42；
UMOD genes：Forward primer is as shown in SEQ ID NO.43, and reverse primer is as shown in SEQ ID NO.44；
SLC12A1 genes：Forward primer is as shown in SEQ ID NO.45, and reverse primer is as shown in SEQ ID NO.46；
CALB1 genes：Forward primer is as shown in SEQ ID NO.47, and reverse primer is as shown in SEQ ID NO.48；
C7 genes：Forward primer is as shown in SEQ ID NO.49, and reverse primer is as shown in SEQ ID NO.50；
S100A2 genes：Forward primer is as shown in SEQ ID NO.51, and reverse primer is as shown in SEQ ID NO.52；
ASS1 genes：Forward primer is as shown in SEQ ID NO.53, and reverse primer is as shown in SEQ ID NO.54；
MT1G genes：Forward primer is as shown in SEQ ID NO.55, and reverse primer is as shown in SEQ ID NO.56；
ABCA8 genes：Forward primer is as shown in SEQ ID NO.57, and reverse primer is as shown in SEQ ID NO.58；
FOSB genes：Forward primer is as shown in SEQ ID NO.59, and reverse primer is as shown in SEQ ID NO.60；
MAOB genes：Forward primer is as shown in SEQ ID NO.61, and reverse primer is as shown in SEQ ID NO.62；
STAP1 genes：Forward primer is as shown in SEQ ID NO.63, and reverse primer is as shown in SEQ ID NO.64；
TFPI2 genes：Forward primer is as shown in SEQ ID NO.65, and reverse primer is as shown in SEQ ID NO.66；
AKR1C2 genes：Forward primer is as shown in SEQ ID NO.67, and reverse primer is as shown in SEQ ID NO.68；
IGFBP6 genes：Forward primer is as shown in SEQ ID NO.69, and reverse primer is as shown in SEQ ID NO.70；
VCAN genes：Forward primer is as shown in SEQ ID NO.71, and reverse primer is as shown in SEQ ID NO.72；
FLRT3 genes：Forward primer is as shown in SEQ ID NO.73, and reverse primer is as shown in SEQ ID NO.74；
MMP7 genes：Forward primer is as shown in SEQ ID NO.75, and reverse primer is as shown in SEQ ID NO.76；
GSTA1 genes：Forward primer is as shown in SEQ ID NO.77, and reverse primer is as shown in SEQ ID NO.78；
CRYAB genes：Forward primer is as shown in SEQ ID NO.79, and reverse primer is as shown in SEQ ID NO.80；
PAH genes：Forward primer is as shown in SEQ ID NO.81, and reverse primer is as shown in SEQ ID NO.82；
IGFBP1 genes：Forward primer is as shown in SEQ ID NO.83, and reverse primer is as shown in SEQ ID NO.84；
ATP6V0A4 genes：Forward primer is as shown in SEQ ID NO.85, and reverse primer is as shown in SEQ ID NO.86；
ALDOB genes：Forward primer is as shown in SEQ ID NO.87, and reverse primer is as shown in SEQ ID NO.88.
8. the kit as described in claim any one of 5-7 is preparing the purposes in judging the preparation of clear-cell carcinoma type.
9. the one group as claimed in claim 1 gene for being used for clear-cell carcinoma molecule parting is being prepared for judging clear-cell carcinoma class Application in the genetic chip of type, the genetic chip include solid phase carrier and probe, it is characterised in that the probe with it is to be measured 44 gene orders and/or its complementary series are hybridized, and the probe is SEQ ID NO.89~SEQ ID NO.132 respectively Shown sequence.
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CN109554471A (en) * 2018-11-29 2019-04-02 华中科技大学同济医学院附属同济医院 Application of DHRS2 gene and reagent for detecting DHRS2 gene expression
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WO2019142636A1 (en) * 2018-01-16 2019-07-25 公立大学法人横浜市立大学 Renal cancer detection method and test drug
CN108203734A (en) * 2018-03-12 2018-06-26 南通大学附属医院 Application of the RHCG genes in treating cancer drug and diagnostic kit is prepared
WO2019174110A1 (en) * 2018-03-12 2019-09-19 南通大学附属医院 Application of rhcg gene in preparation of drug for treating cancer and diagnostic kit
CN108866194A (en) * 2018-08-16 2018-11-23 杭州可帮基因科技有限公司 One group of gene and its application for bladder cancer detection
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CN109554471A (en) * 2018-11-29 2019-04-02 华中科技大学同济医学院附属同济医院 Application of DHRS2 gene and reagent for detecting DHRS2 gene expression
WO2021018116A1 (en) * 2019-07-30 2021-02-04 立森印迹诊断技术有限公司 Tumour marker and use thereof
CN114032252A (en) * 2021-11-01 2022-02-11 武汉爱博泰克生物科技有限公司 Expression method and application of recombinant human MMP-7 protein
CN115851909A (en) * 2022-11-21 2023-03-28 郑州大学第一附属医院 Application of reagent for detecting and/or regulating FOSB gene in preparation of product for predicting and/or treating abdominal aortic aneurysm
CN115851909B (en) * 2022-11-21 2023-09-08 郑州大学第一附属医院 Application of reagent for detecting FOSB gene in preparation of product for diagnosing abdominal aortic aneurysm

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