CN107696368B - Forming die for coating of suction-type powder medicament - Google Patents
Forming die for coating of suction-type powder medicament Download PDFInfo
- Publication number
- CN107696368B CN107696368B CN201710930152.5A CN201710930152A CN107696368B CN 107696368 B CN107696368 B CN 107696368B CN 201710930152 A CN201710930152 A CN 201710930152A CN 107696368 B CN107696368 B CN 107696368B
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- coating
- mold
- die
- die shell
- shell
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C41/00—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
- B29C41/34—Component parts, details or accessories; Auxiliary operations
- B29C41/38—Moulds, cores or other substrates
- B29C41/40—Cores
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C41/00—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
- B29C41/34—Component parts, details or accessories; Auxiliary operations
- B29C41/42—Removing articles from moulds, cores or other substrates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C41/00—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
- B29C41/34—Component parts, details or accessories; Auxiliary operations
- B29C41/46—Heating or cooling
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Moulds For Moulding Plastics Or The Like (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Abstract
The invention discloses a forming die for a coating of a suction-type powder medicament, which comprises a die shell, wherein a heating system and a refrigerating system are arranged in the die shell, the die shell is provided with a plurality of ventilation channels which are sunken towards the interior of the die shell, the joint of the ventilation channels and the surface of the die shell is provided with a ventilation hole, and a plugging strip which can be drawn out and inserted is arranged in the ventilation channels. According to the invention, the vent holes can be completely closed when the coating is prepared, and opened when the coating is peeled off, so that the preparation and peeling of the coating are not influenced, the design is ingenious, the preparation efficiency of the coating is greatly improved, the breakage rate of the coating is greatly reduced, and the production efficiency and the product percent of pass are improved.
Description
Technical Field
The invention relates to a forming die for a coating of a suction-type powder medicament, belonging to the technical field of pharmaceutical coating.
Background
The powder medicament is easy to absorb moisture in the air to change moisture and deteriorate and is easy to spill in the transportation and use processes, so in order to improve the use safety of the powder medicament and guarantee the product quality, generally, the powder medicament needs to be coated before leaving a factory, and the powder medicament is injected into the coating, so that the coating can prevent the powder medicament from contacting with the atmosphere, keep dry, avoid oxidation and moisture absorption and deterioration, and also can quantify the medicament according to the coating.
Currently, the coating technology for commercially available solid dosage forms is liquid coating technology. Typically, a mixture of the polymeric material, pigment and excipients is dissolved in a suitable organic solvent (for water-insoluble polymeric materials) or water (for water-soluble polymeric materials) to form a solution, or dispersed in water to form a dispersion, which is then sprayed onto the formulation and dried by continued heating (typically using hot air) until a dry coating film is formed.
However, the inherent disadvantages of using organic solvents or water are becoming more and more significant and are becoming unacceptable to the pharmaceutical industry. These disadvantages include evaporation of the organic solvent or water, which is very energy intensive. This causes a considerable increase in the cost of coating and inevitably lengthens the operation time.
Disclosure of Invention
In order to solve the existing problems, the invention discloses a forming die for coating of a suction-type powder medicament, which has the following specific technical scheme:
forming die of capsule of suction type powder medicament, including the mould casing, the inside of mould casing is provided with heating system and refrigerating system, the mould casing is provided with a plurality of ventilation channels of its inside sunken of orientation, the surface junction of ventilation channel and mould casing is provided with the air vent, be provided with in the ventilation channel and take out and the inserted stifled strip.
Both ends of the vent channel extend to the edge of the mold shell, and the blocking strip is inserted into the vent channel to block all vent holes.
One end of the die shell is hemispherical, the periphery of the hemisphere extends to be in a cylinder shape, and a ring-shaped blocking piece surrounding the cylinder is arranged at the end part of the cylinder shape.
The blocking strip penetrates through the corresponding position of the blocking piece.
The surface of mould casing is provided with temperature-sensing ware, temperature-sensing ware can be wireless transmits the mould casing surface temperature that it sensed for temperature monitor, temperature monitor sets up outside the mould casing, and with mould casing contactless.
Several of the ventilation channels are parallel to each other and all extend from the edge of the cylindrical shape to the end of the hemisphere to the opposite edge of the cylinder.
The heating system comprises electric heating wires close to the mould shell, the electric heating wires are distributed in the mould shell in a meshed and interweaving mode, and the tail ends of power wires of the electric heating wires are connected with a power plug.
The refrigerating system comprises a refrigerating sheet located between the electric heating wire and the mold shell, and the tail end of a power line of the refrigerating sheet is connected with a power plug.
The working principle of the invention is as follows:
the prepared coating is taken down from the mold shell in a vacuum adsorption mode, and when the coating is adsorbed from the outside of the coating, the surface of the coating, which is in contact with the mold shell, allows air to enter a gap between the coating and the mold shell, so that the coating is adsorbed, separated from the mold shell, taken down safely and cannot be damaged by adsorption.
The invention has the beneficial effects that:
according to the invention, the vent holes can be completely closed when the coating is prepared, and opened when the coating is peeled off, so that the preparation and peeling of the coating are not influenced, the design is ingenious, the preparation efficiency of the coating is greatly improved, the breakage rate of the coating is greatly reduced, and the production efficiency and the product percent of pass are improved.
Drawings
Figure 1 is a schematic view of the structure of the present invention,
figure 2 is a cross-sectional view taken along line a-a of figure 1,
list of reference numerals: 1-mould shell, 2-plugging strip, 3-ventilation channel and 4-baffle.
Detailed Description
The invention is further elucidated with reference to the drawings and the detailed description. It should be understood that the following detailed description is illustrative of the invention only and is not intended to limit the scope of the invention.
Fig. 1 is a schematic structural diagram of the present invention, fig. 2 is a sectional view taken along line a-a of fig. 1, and the structural names marked correspondingly in the diagram are: the mold comprises a mold shell 1, a blocking strip 2, a vent channel 3 and a blocking sheet 4.
It can be seen from the attached drawing that the forming die for the coating of the suction-release type powder medicament comprises a die shell, wherein a heating system and a refrigerating system are arranged inside the die shell, the die shell is provided with a plurality of ventilation channels sunken towards the inside of the die shell, the surface connection parts of the ventilation channels and the die shell are provided with air holes, and the ventilation channels are internally provided with blocking strips which can be drawn out and inserted. The mould shell is used for coating material spraying and then forming, the heating system is used for heating the mould shell to a preset temperature before coating material spraying, and the refrigerating system is used for cooling the mould shell after coating material spraying is finished, so that the coating is cooled and formed. When heating the mould shell and spraying the coating material, the vent hole is blocked, when peeling off the coating, the vent hole is opened, so that the vacuum adsorption coating is facilitated, and when the lower surface of the coating is communicated with the atmosphere, the formation of vacuum is avoided, and the coating is sucked to be broken. The air vent is ingeniously opened and closed through the blocking strips, the control is convenient, and the manufacturing is simple.
Both ends of the vent channel extend to the edge of the mold shell, and the blocking strip is inserted into the vent channel to block all vent holes. The vent passage is communicated with the external atmosphere, and when the coating is stripped, the inner surface of the coating is consistent with the external atmosphere pressure.
One end of the die shell is hemispherical, the periphery of the hemisphere extends to be in a cylinder shape, and a ring-shaped blocking piece surrounding the cylinder is arranged at the end part of the cylinder shape. The baffle is the edge of the coating.
The blocking strip penetrates through the corresponding position of the blocking piece. The pulling and moving position of the blocking strip is convenient.
The surface of mould casing is provided with temperature-sensing ware, temperature-sensing ware can be wireless transmits the mould casing surface temperature that it sensed for temperature monitor, temperature monitor sets up outside the mould casing, and with mould casing contactless. The surface temperature of the die shell can be known in real time through the temperature sensor and the temperature controller, and the temperature can be controlled accurately.
Several of the ventilation channels are parallel to each other and all extend from the edge of the cylindrical shape to the end of the hemisphere to the opposite edge of the cylinder. Every channel of ventilating all forms a complete route, and both ends all link up with the external world, and do not interweave, prevent that stifled strip pull from receiving the influence of other stifled strips.
The heating system comprises electric heating wires close to the mould shell, the electric heating wires are distributed in the mould shell in a meshed and interweaving mode, and the tail ends of power wires of the electric heating wires are connected with a power plug. The power supply is plugged in through the power supply plug, and the electric heating wire heats the mold shell.
The refrigerating system comprises a refrigerating sheet located between the electric heating wire and the mold shell, and the tail end of a power line of the refrigerating sheet is connected with a power plug. The refrigeration piece is used for cooling the temperature base in the mold shell, and finally the mold shell is cooled.
The technical means disclosed by the scheme of the invention are not limited to the technical means disclosed by the technical means, and the technical scheme also comprises the technical scheme formed by any combination of the technical characteristics.
In light of the foregoing description of the preferred embodiment of the present invention, many modifications and variations will be apparent to those skilled in the art without departing from the spirit and scope of the invention. The technical scope of the present invention is not limited to the content of the specification, and must be determined according to the scope of the claims.
Claims (5)
1. The forming die for the coating of the suction-release type powder medicament is characterized by comprising a die shell, wherein a heating system and a refrigerating system are arranged inside the die shell, the die shell is provided with a plurality of ventilation channels which are sunken towards the interior of the die shell, the joint of the ventilation channels and the surface of the die shell is provided with a ventilation hole, and a plugging strip which can be drawn out and inserted is arranged in the ventilation channels;
both ends of the vent channel extend to the edge of the mold shell, and the blocking strip is inserted into the vent channel to block all vent holes;
one end of the die shell is hemispherical, the periphery of the hemispherical shape extends to form a cylindrical shape, and a circle of annular blocking sheet surrounding the cylindrical shape is arranged at the end part of the cylindrical shape;
the blocking strip penetrates through the corresponding position of the blocking piece;
the absorption and desorption mode adopts vacuum absorption.
2. The mold for molding a coating of a suction type powdered medicament as claimed in claim 1, wherein the surface of the mold housing is provided with a temperature sensor capable of wirelessly transmitting the temperature sensed by the temperature sensor to a temperature indicator, the temperature indicator being disposed outside the mold housing without contacting the mold housing.
3. The mold for forming a coating of a suck-off powder pharmaceutical agent according to claim 1, wherein said plurality of vent channels are parallel to each other and each extend from an edge of the cylindrical shape to an end of the hemispherical shape and then to an opposite edge of the cylindrical shape.
4. The mold for molding a coating of a suction-type powdered medicament as claimed in claim 1, wherein the heating system comprises electric heating wires close to the mold housing, the electric heating wires are interlaced and distributed in the mold housing in a net shape, and a power plug is connected to the end of a power cord of the electric heating wires.
5. The forming die for coating of suction-type powder medicament as claimed in claim 4, wherein the refrigerating system comprises a refrigerating sheet located between the electric heating wire and the die housing, and a power plug is connected to the end of the power cord of the refrigerating sheet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710930152.5A CN107696368B (en) | 2017-10-09 | 2017-10-09 | Forming die for coating of suction-type powder medicament |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710930152.5A CN107696368B (en) | 2017-10-09 | 2017-10-09 | Forming die for coating of suction-type powder medicament |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107696368A CN107696368A (en) | 2018-02-16 |
| CN107696368B true CN107696368B (en) | 2020-07-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710930152.5A Active CN107696368B (en) | 2017-10-09 | 2017-10-09 | Forming die for coating of suction-type powder medicament |
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| Country | Link |
|---|---|
| CN (1) | CN107696368B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101766537A (en) * | 2010-02-26 | 2010-07-07 | 罗彦凤 | Dry-method coating machine |
| CN107049786A (en) * | 2017-06-13 | 2017-08-18 | 裴天锋 | A kind of granulated drug Intelligent Package device |
-
2017
- 2017-10-09 CN CN201710930152.5A patent/CN107696368B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101766537A (en) * | 2010-02-26 | 2010-07-07 | 罗彦凤 | Dry-method coating machine |
| CN107049786A (en) * | 2017-06-13 | 2017-08-18 | 裴天锋 | A kind of granulated drug Intelligent Package device |
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| Publication number | Publication date |
|---|---|
| CN107696368A (en) | 2018-02-16 |
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