CN107684774B - Filtering device - Google Patents

Filtering device Download PDF

Info

Publication number
CN107684774B
CN107684774B CN201710910327.6A CN201710910327A CN107684774B CN 107684774 B CN107684774 B CN 107684774B CN 201710910327 A CN201710910327 A CN 201710910327A CN 107684774 B CN107684774 B CN 107684774B
Authority
CN
China
Prior art keywords
liquid
pipe
filter
sealing
liquid storage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201710910327.6A
Other languages
Chinese (zh)
Other versions
CN107684774A (en
Inventor
赵玉慧
杨翔
陈锦河
楼建荣
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leide Biosciences Co ltd
Original Assignee
Leide Biosciences Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leide Biosciences Co ltd filed Critical Leide Biosciences Co ltd
Priority to CN201710910327.6A priority Critical patent/CN107684774B/en
Publication of CN107684774A publication Critical patent/CN107684774A/en
Application granted granted Critical
Publication of CN107684774B publication Critical patent/CN107684774B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D36/00Filter circuits or combinations of filters with other separating devices
    • B01D36/003Filters in combination with devices for the removal of liquids

Abstract

The invention discloses a filtering device, and relates to the technical field of biological medicines. The filtering device comprises a filtering pipe, a sealing plug and a separator, and a sealing groove is arranged in the filtering pipe; the sealing plug is detachably connected to the sealing groove, a filter membrane is arranged at the top of the sealing plug, and a through hole is formed in the sealing plug; the separator is arranged in the filter pipe and is positioned above the sealing groove, the separator is provided with a first liquid storage groove for storing liquid of the target layer, the two sides of the separator are provided with a first liquid pipe and a second liquid pipe, a water stop filter element is arranged in the first liquid pipe, and the second liquid pipe is connected with the first liquid storage groove. According to the filtering device, unnecessary impurities are filtered by the filter membrane, the needed liquid enters the second liquid storage tank through the filter membrane, and the water stopping filter element in the first liquid pipe absorbs water to expand, so that the liquid in the second liquid storage tank is pressed into the second liquid pipe and flows into the first liquid storage tank, and the problem that the existing filtering device cannot directly take out the liquid in the target layer in the test tube is solved.

Description

Filtering device
Technical Field
The invention relates to the technical field of biological medicines, in particular to a filtering device.
Background
The supernatant is transparent liquid for precipitating the upper layer in blood layering test, and the component is plasma. Also known as a supernatant layer, refers to a liquid above a deposited solid.
In general, the supernatant is collected in a laboratory by centrifugation and is then removed by pipetting. However, centrifugation can result in mixing of all liquids, and in some special cases (e.g., excluding uppermost liquid contamination), the experimenter needs to withdraw the liquid from the target layer of the tube without disturbing the layering of the liquid and without centrifugation.
Therefore, there is a need for a filtering device to solve the above problems.
Disclosure of Invention
The invention aims to provide a filtering device to solve the problem that the prior filtering device can not directly take out the liquid in a target layer in a test tube.
To achieve the purpose, the invention adopts the following technical scheme:
a filtration device comprising:
a sealing groove is arranged in the bottom of the filter pipe;
the sealing plug is detachably connected with the sealing groove, a filter membrane is arranged at the top of the sealing plug, and a through hole is formed in the sealing plug;
the separator is arranged in the filter pipe and is positioned above the sealing groove, a first liquid storage groove for storing liquid of the target layer is formed in the separator, a first liquid pipe and a second liquid pipe are arranged on two sides of the separator, a water stop filter element is arranged in the first liquid pipe, and the second liquid pipe is connected with the first liquid storage groove.
Preferably, the sealing groove is screwed to the sealing plug.
Preferably, a step surface is arranged at the top of the sealing groove, and the filter membrane is abutted against the step surface.
Preferably, a bulge is arranged outside the sealing plug, and the outer diameter of the bulge is matched with the inner diameter of the test tube of the liquid to be separated.
Preferably, a second liquid storage groove is arranged in the bottom of the filter pipe, is positioned above the sealing groove and is communicated with the first liquid pipe.
Preferably, the bottom end of the second liquid pipe is positioned at the bottom of the second liquid storage tank, and the top end of the second liquid pipe is positioned at the top of the first liquid storage tank.
Preferably, the separator is plastic.
Preferably, the water stop filter element is water-swelling rubber or polyethylene or resin.
Preferably, the filter tube further comprises a sealing cover, and the sealing cover is arranged at the top of the filter tube.
The invention has the beneficial effects that:
according to the invention, the filter device is provided, unnecessary impurities are filtered by utilizing the filter membrane, the needed liquid enters the second liquid storage tank through the filter membrane, and then the water-stop filter element in the first liquid channel absorbs water to expand, so that the liquid in the second liquid storage tank is pressed into the second liquid channel and flows into the first liquid storage tank, and the problem that the existing filter device cannot directly take out the liquid in the target layer in the test tube is solved; the sealing plug is in threaded connection with the filter pipe, so that the sealing plug and the filter pipe are convenient to assemble and disassemble, and liquid cannot enter the filter pipe through a gap between the sealing plug and the filter pipe, and the influence of impurities is avoided; the outside of the sealing plug is provided with the bulge, so that the filter tube and the sealing plug can enter the test tube of the liquid to be separated after being assembled and molded, and the liquid can only enter the filter tube through the through hole arranged on the sealing plug and the filter membrane arranged at the top of the sealing plug by the bulge arrangement mode; the water-stopping filter element is adopted, the water-stopping filter element can pass through air before the water-stopping filter element is not contacted with liquid, and the water-stopping filter element can absorb water and expand after contacting with the liquid, so that a first liquid path is blocked, and then the liquid in a second liquid storage tank can enter a second liquid path from the bottom of the second liquid storage tank and enter the first liquid storage tank; the bottom of the second liquid path is arranged at the bottom of the second liquid storage tank, and the bottom liquid is more beneficial to better data obtained by technicians in the experimental process relative to the upper liquid.
Drawings
Embodiments of the present invention will now be described, by way of example only, with reference to the accompanying drawings, in which
FIG. 1 is a schematic view of a filtering device according to an embodiment of the present invention;
FIG. 2 is a cross-sectional view of FIG. 1;
fig. 3 is a schematic structural view of a sealing cover according to an embodiment of the present invention.
The figures are labeled as follows:
1. a filter tube; 11. a second reservoir; 12; sealing grooves; 13. a threaded hole; 14. a step surface;
2. a sealing plug; 21. a protrusion; 22. a thread; 23. a through hole;
3. a separator; 31. a first reservoir;
4. a first liquid pipe; 41. a water stop filter element;
5. a second liquid pipe;
6. a filter membrane;
7. sealing cover.
Detailed Description
The technical scheme of the invention is further described below by the specific embodiments with reference to the accompanying drawings.
As shown in fig. 1 to 3, the present embodiment provides a filtering device, which includes a filtering tube 1, a sealing plug 2 and a separator 3, wherein a sealing groove 12 is provided in the bottom of the filtering tube 1, the sealing plug 2 is detachably connected to the sealing groove 12, a filter membrane 6 is provided at the top of the sealing plug 2, and a through hole 23 is provided in the sealing plug 2; the separator 3 is arranged in the filter tube 1 and is positioned above the sealing groove 12, the separator 3 is provided with a first liquid storage groove 31 for storing liquid of a target layer, two sides of the separator 3 are provided with a first liquid pipe 4 and a second liquid pipe 5, a water stop filter element 41 is arranged in the first liquid pipe 4, and the second liquid pipe 5 is connected with the first liquid storage groove 31. The invention provides a filtering device, which utilizes the filter membrane 6 to filter out unwanted impurities, the needed liquid enters the second liquid storage tank 11 through the filter membrane 6, and then the liquid in the second liquid storage tank 11 is pressed into the second liquid pipe 5 and flows into the first liquid storage tank 31 due to the water-stop filter element 41 in the first liquid pipe 4 absorbing water and expanding, so that the problem that the prior filtering device can not directly take out the liquid in the target layer in the test tube is solved.
Specifically, be equipped with screw hole 13 in the seal groove 12, seal plug 2 are equipped with screw thread 22 outward, and seal groove 12 and seal plug 2 threaded connection adopt seal plug 2 and filter tube 1 threaded connection, not only can make two easy dismounting, can also make liquid can not get into filter tube 1 inside through the gap between seal plug 2 and the filter tube 1, have avoided the influence of impurity.
Specifically, the top of seal groove 12 is provided with step face 14, and filter membrane 6 butt in step face 14, divides into two spaces with filter tube 1's inside through filter membrane 6, and the space of filter membrane 6 below passes through liquid earlier, and the impurity that the particle diameter is big is blocked by filter membrane 6 to required supernatant or target layer liquid just can enter into second reservoir 11 through filter membrane 6.
Specifically, the bulge 21 is arranged outside the sealing plug 2, the outer diameter of the bulge 21 is matched with the inner diameter of the test tube of the liquid to be separated, the bulge 21 is arranged outside the sealing plug 2, the filter tube 1 and the sealing plug 2 can enter the test tube of the liquid to be separated after being assembled and formed, and the liquid in the target layer can only enter the filter tube 1 through the through hole 23 penetrating through the sealing plug 2 and the filter membrane 6 arranged at the top of the sealing plug 2 in a setting mode of the bulge 21.
Specifically, a second liquid storage tank 11 is arranged in the filter pipe 1, the second liquid storage tank 11 is located above the sealing groove 12 and is connected with the first liquid pipe 4, the second liquid storage tank 11 firstly stores target layer liquid filtered by the filter membrane 6, as the liquid increases, the liquid level in the second liquid storage tank 11 rises, when the liquid reaches the position of the first liquid pipe 4 where the water filter element 41 is stopped, the liquid contacts with the water stop filter element 41, the water stop filter element 41 expands and forms a strong airtight colloid, the liquid and air are prevented from flowing through, and the liquid is pressed into the second liquid pipe 5 due to the pressure.
Specifically, the bottom end of the second liquid pipe 5 is located at the bottom of the second liquid storage tank 11, the top end is located at the top of the first liquid storage tank 31, and because the liquid at the bottom of the second liquid storage tank 11 is more beneficial to the technical personnel to obtain better data in the experimental process relative to the liquid at the upper layer of the second liquid storage tank, the bottom end of the second liquid pipe 5 is arranged at the bottom of the second liquid storage tank 11, when the liquid enters the second liquid pipe 5 to gradually rise, the liquid reaches the top end of the second liquid pipe 5, smoothly flows into the first liquid storage tank 31, and finally the acquisition of the liquid at the target layer is completed.
Specifically, the separator 3 is preferably plastic as long as the separator 3 satisfies a material that can not react with the target layer liquid, such as rubber, and in this embodiment, the separator 3 serves only to separate the first liquid pipe 4 from the second liquid pipe 5 and to acquire the target layer liquid by using the first liquid storage tank 31 provided therein.
Specifically, the water-stop filter element 41 is water-swelling rubber or polyethylene or resin, belongs to water-swelling polymer materials, and is a novel waterproof material with self-adhesion performance, which is synthesized by polymer, inorganic water-swelling materials, rubber and auxiliary agents. Of these, the polyethylene is preferably Ultra high molecular weight polyethylene (Ultra-high molecular weight polyethylene, UHMW-PE, sometimes abbreviated as PE) which is a polyethylene having a molecular weight of 150 ten thousand or more, and porous sintered plastic is formed after sintering UHMW-PE. Whereas water-swellable rubbers are mainly composed of hydrocarbon chain segments of high degree of polymerization, are inherently hydrophobic. If hydrophilic substances or groups exist in the rubber, the rubber can expand due to water absorption after meeting water. When the water-swelling rubber contacts with water, water molecules enter the rubber through physical actions such as diffusion, capillary action, surface adsorption and the like, and extremely strong affinity is formed with hydrophilic groups in the rubber. The hydrophilic substance continuously absorbs water to cause the water to deform the rubber, and when the deformation resistance and the osmotic pressure difference of the rubber are equal, the measured expansion rate is the maximum expansion rate of still water. In general, water-swellable rubber is used under closed conditions, and the swelling rate after water is not up to the maximum swelling rate of still water. Therefore, the contact pressure between the expansion rubber and the restraint body is generated, and the water-swelling rubber can play the role of sealing and stopping water by virtue of the contact pressure. The water stop filter 41 is also called a self-sealing filter or a spill-proof filter, and is obtained by embedding a polymer elastomer into a porous structure of a PE sintered filter by a special process. In the dry state, the polymeric elastomer does not swell and the airways between the PE networks remain highly breathable. After contacting with water, the polymer elastomer expands rapidly to block the porous structure, the air passage is closed, and the water solution cannot pass through.
Specifically, the filtering device further comprises a sealing cover 7, the sealing cover 7 is covered on the top of the filtering tube 1, after the target layer liquid is obtained, the liquid in the first liquid storage tank 31 can be selected to be removed by a liquid transferring gun, and the top of the filtering tube 1 can be sealed by the sealing cover 7 for preservation; wherein the top of the filter tube 1 is designed to be shaped to fit the sealing cap 7 to ensure a perfect seal.
It is to be understood that the above examples of the present invention are provided for clarity of illustration only and are not limiting of the embodiments of the present invention. Other variations or modifications of the above teachings will be apparent to those of ordinary skill in the art. It is not necessary here nor is it exhaustive of all embodiments. Any modification, equivalent replacement, improvement, etc. which come within the spirit and principles of the invention are desired to be protected by the following claims.

Claims (8)

1. A filter device, comprising:
a sealing groove (12) is arranged in the bottom of the filter pipe (1);
the sealing plug (2) is detachably connected with the sealing groove (12), a filter membrane (6) is arranged at the top of the sealing plug (2), and a through hole (23) is formed in the sealing plug (2);
the separator (3) is arranged in the filter pipe (1) and is positioned above the sealing groove (12), the separator (3) is provided with a first liquid storage groove (31) for storing target layer liquid, two sides of the separator (3) are provided with a first liquid pipe (4) and a second liquid pipe (5), a water stopping filter element (41) is arranged in the first liquid pipe (4), and the second liquid pipe (5) is connected with the first liquid storage groove (31);
a second liquid storage tank (11) is arranged in the bottom of the filter pipe (1), and the second liquid storage tank (11) is positioned above the sealing groove (12) and is communicated with the first liquid pipe (4);
the second liquid pipe (5) is communicated with the first liquid storage groove (31);
the water stop filter element (41) can absorb water and expand so as to block the first liquid path;
the bottom end of the second liquid pipe (5) is positioned at the bottom of the second liquid storage tank (11).
2. A filter device according to claim 1, characterized in that the sealing groove (12) is screwed with the sealing plug (2).
3. The filtering device according to claim 2, characterized in that the top of the sealing groove (12) is provided with a step surface (14), and the filter membrane (6) abuts against the step surface (14).
4. A filter device according to claim 1, characterized in that a protrusion (21) is provided outside the sealing plug (2), the outer diameter of the protrusion (21) being adapted to the inner diameter of the test tube of the liquid to be separated.
5. The filter device according to claim 1, characterized in that the top end of the second liquid pipe (5) is located at the top of the first liquid reservoir (31).
6. The filter device according to claim 1, characterized in that the separator (3) is plastic.
7. The filter device according to claim 6, characterized in that the water stop filter element (41) is of water-swellable rubber or polyethylene or resin.
8. The filtering device according to any one of claims 1 to 7, further comprising a sealing cover (7), wherein the sealing cover (7) is arranged on the top of the filtering tube (1) in a covering manner.
CN201710910327.6A 2017-09-29 2017-09-29 Filtering device Active CN107684774B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710910327.6A CN107684774B (en) 2017-09-29 2017-09-29 Filtering device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710910327.6A CN107684774B (en) 2017-09-29 2017-09-29 Filtering device

Publications (2)

Publication Number Publication Date
CN107684774A CN107684774A (en) 2018-02-13
CN107684774B true CN107684774B (en) 2023-09-22

Family

ID=61153789

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710910327.6A Active CN107684774B (en) 2017-09-29 2017-09-29 Filtering device

Country Status (1)

Country Link
CN (1) CN107684774B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108760455B (en) * 2018-06-12 2021-01-01 广州市雷德生物科技有限公司 Blood filtering device

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1005910A2 (en) * 1998-12-05 2000-06-07 Becton Dickinson and Company Centrifuge tube with cylindrically symmetric separation element, liner and cap
JP2009236513A (en) * 2008-03-26 2009-10-15 Ihi Corp Sampler and sampling method using it
CN102350150A (en) * 2011-06-21 2012-02-15 上海隧道工程股份有限公司 Filter pipe for suction and discharge of biogas-containing stratum gas
CN202146669U (en) * 2011-07-18 2012-02-22 四川逢春制药有限公司 Pipe filter
WO2013059526A1 (en) * 2011-10-18 2013-04-25 The Trustees Of Columbia University In The City Of New York Medical apparatus and method for collecting biological samples
EP2670530A1 (en) * 2011-01-31 2013-12-11 Sartorius Stedim Biotech GmbH Filtration container
CN103721567A (en) * 2013-12-26 2014-04-16 天津博纳艾杰尔科技有限公司 Sample solution purifying device based on hollow fiber nanofiltration membrane material
CN205443288U (en) * 2016-03-24 2016-08-10 深圳逗点生物技术有限公司 Nucleic acid extraction device
JP2017015710A (en) * 2015-07-06 2017-01-19 富士フイルム株式会社 Blood test kit and analysis method using the same
CN207307380U (en) * 2017-09-29 2018-05-04 广州市雷德生物科技有限公司 A kind of filtration apparatus

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1005910A2 (en) * 1998-12-05 2000-06-07 Becton Dickinson and Company Centrifuge tube with cylindrically symmetric separation element, liner and cap
JP2009236513A (en) * 2008-03-26 2009-10-15 Ihi Corp Sampler and sampling method using it
EP2670530A1 (en) * 2011-01-31 2013-12-11 Sartorius Stedim Biotech GmbH Filtration container
CN102350150A (en) * 2011-06-21 2012-02-15 上海隧道工程股份有限公司 Filter pipe for suction and discharge of biogas-containing stratum gas
CN202146669U (en) * 2011-07-18 2012-02-22 四川逢春制药有限公司 Pipe filter
WO2013059526A1 (en) * 2011-10-18 2013-04-25 The Trustees Of Columbia University In The City Of New York Medical apparatus and method for collecting biological samples
CN103721567A (en) * 2013-12-26 2014-04-16 天津博纳艾杰尔科技有限公司 Sample solution purifying device based on hollow fiber nanofiltration membrane material
JP2017015710A (en) * 2015-07-06 2017-01-19 富士フイルム株式会社 Blood test kit and analysis method using the same
CN205443288U (en) * 2016-03-24 2016-08-10 深圳逗点生物技术有限公司 Nucleic acid extraction device
CN207307380U (en) * 2017-09-29 2018-05-04 广州市雷德生物科技有限公司 A kind of filtration apparatus

Also Published As

Publication number Publication date
CN107684774A (en) 2018-02-13

Similar Documents

Publication Publication Date Title
CN105784455B (en) Extract structure and liquid preprocessing device
RU2469696C2 (en) Vented vial adapter provided with aerosol entrapment filter
JP3890066B2 (en) Blood separation instrument and blood separation device
WO2006055993A1 (en) Separating device, in particular for bodily fluids, and receptacle equipped with this separating device
CN105722576A (en) Novel filter medium for obtaining plasma, and associated filtration device and method
KR20070049110A (en) Blood drawing device
US20050051486A1 (en) Biological fluid filtration apparatus
US6368741B1 (en) Stopper plug for storage batteries
CN107684774B (en) Filtering device
ES2842239T3 (en) Capillary pressure restoration mechanism and applications
WO2015045688A1 (en) Blood component separation device
US20080223798A1 (en) Apparatus and System For Displacing Gas in a Biological Fluid Processing System
CN106644886A (en) Method for testing seepage performance of thermoplastic plastic mixed gas and test device thereof
WO2009128892A2 (en) Flexible membrane valve for cell culture vessel
US7806274B2 (en) Vacuum filtration device
KR200481969Y1 (en) Filter with vent structure
KR20170040062A (en) Drain unit of medical injection set
RU2422160C1 (en) Disposable hemosorption column temos-ks
CN106676676B (en) Blood filter based on polyacrylonitrile based activated carbon fiber
US10561767B2 (en) Medical suction device
CN207307380U (en) A kind of filtration apparatus
US5070899A (en) Check valve
CN208274794U (en) A kind of exhaust dropping funnel certainly
JP2007003479A (en) Blood separation device
CN208032331U (en) Use for laboratory blood filter

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant