CN107661358A - The freeze drying process of leech - Google Patents
The freeze drying process of leech Download PDFInfo
- Publication number
- CN107661358A CN107661358A CN201711147622.7A CN201711147622A CN107661358A CN 107661358 A CN107661358 A CN 107661358A CN 201711147622 A CN201711147622 A CN 201711147622A CN 107661358 A CN107661358 A CN 107661358A
- Authority
- CN
- China
- Prior art keywords
- leech
- freeze
- drying process
- incubated
- freeze drying
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Mechanical Engineering (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Storage Of Fruits Or Vegetables (AREA)
Abstract
The invention discloses a kind of freeze drying process of leech, it is related to leech processing technique field, this method comprises the following steps：After leech is cleaned up, it is put into screw fast refreezer and carries out pre-freeze, pre-freezing temperature is 18~13 DEG C, and the time is 30~45min；The good leech sabot of pre-freeze is put into vacuum freeze drier and freezed, the central temperature of leech is reduced to 28~32 DEG C, freezes the moisture in leech；Below 20Pa is evacuated to, 20 DEG C are then to slowly warm up in 2h, is incubated 0.5~1h, then 5 DEG C are risen in 1h；30 DEG C are at the uniform velocity warming up in 2h, is incubated 0.5~1h, until leech water content drops to less than 3%.The present invention solves the problems, such as that existing freeze-drying leech has long processing time.
Description
Technical field
The present invention relates to leech processing technique field, especially a kind of freeze drying process of leech.
Background technology
Leech, leech is commonly called as, is the general name of Hirudinea animal, it is mainly containing protein, fat, carbohydrate, heparin
(heparin), antithrombase, also containing macroelement needed by human（Sodium, potassium, calcium, magnesium etc.）And trace element（Iron, manganese, zinc,
Silicon, aluminium etc.）, the salty bitterness of taste puts down, have blood-breaking, by the stasis of blood, stimulate the menstrual flow with dissipating bind and other effects, its pharmacological action affirmative, and without obvious poison
Side effect, it is widely used in tcm clinical practice, curative for effect in a variety of diseases because caused by hemostasis are treated, indication is related to heart and brain
Blood vessel, liver kidney and dysemia, trauma pain and breathing, nervous system and cancer etc..After leech is generally processed into dried product, then
Processing is used as medicine, and the processing of existing leech use Vacuum Freezing ＆ Drying Technology, relative to traditional sun-dried method, having one's hair waved method, alkali burning method,
Ash buries method, cigarette buries method, the vexed method of wine, salt preparation method, airing method and oven drying method, and this technology can discharge 97% or so moisture, because being
The heat-sensitive substance such as more than 17h, protein, cell is freeze-dried in a low temperature of -70~-45 DEG C to be unlikely to deteriorate or damage, and is tied
Structure is stable, and loss of effective components is few, and drug effect is high, but the temperature of this method is low, long processing time, high energy consumption.
The content of the invention
It is an object of the invention to provide a kind of freeze drying process of leech, this method can solve existing freeze-drying leech
The problem of long processing time be present.
In order to solve the above problems, the technical solution adopted by the present invention is：The freeze drying process of this leech includes following step
Suddenly：
1）After leech is cleaned up, it is put into screw fast refreezer and carries out pre-freeze, pre-freezing temperature is -18~-13 DEG C, the time 30
~45min；
2）The good leech sabot of pre-freeze is put into vacuum freeze drier and freezed, the central temperature of leech is reduced to -28~-
32 DEG C, freeze the moisture in leech；
3）Below 20Pa is evacuated to, -20 DEG C are then to slowly warm up in 2h, is incubated 0.5~1h, then risen in 1h
5℃；
4）30 DEG C are at the uniform velocity warming up in 2h, is incubated 0.5~1h, until leech water content drops to less than 3%.
In the technical scheme of the freeze drying process of above-mentioned leech, more specifically technical scheme can also be：Step 2）Middle elder generation-
15 DEG C and -25 DEG C maintain 30min respectively, and the central temperature of leech then is reduced into -30 DEG C again.
Further, step 3）Middle leech water content drops to less than 8%.
Further, step 2）Leech be emitted in individual layer in disk.
By adopting the above-described technical solution, the present invention has the advantages that compared with prior art：Use spiral
Instant freezer pre-freeze, follow-up freeze-drying time can be shortened, cooling stage by stage and the at the uniform velocity temperature setting in heating and each stage, energy
Freeze-drying time is reduced, and dry word frequency does not ftracture, be non-discolouring, nutrient loss is few, rehydration is good after drying.
Embodiment
With reference to embodiment, the invention will be further described：
Embodiment 1
The freeze drying process of the leech of the present embodiment comprises the following steps：
1）After leech is cleaned up, it is put into screw fast refreezer and carries out pre-freeze, pre-freezing temperature is -13 DEG C, time 45min；
2）The good leech of pre-freeze is emitted in disk in individual layer, is put into vacuum freeze drier and freezes, first at -15 DEG C and -25
DEG C 30min is maintained respectively, then the central temperature of leech is reduced to -28 DEG C, freeze the moisture in leech；
3）Below 20Pa is evacuated to, -20 DEG C are then to slowly warm up in 2h, is incubated 0.5h, then 5 are risen in 1h
DEG C, leech water content is dropped to 8%；
4）30 DEG C are at the uniform velocity warming up in 2h, is incubated 0.5h, until leech water content drops to 3%.
Embodiment 2
The freeze drying process of the leech of the present embodiment comprises the following steps：
1）After leech is cleaned up, it is put into screw fast refreezer and carries out pre-freeze, pre-freezing temperature is -15 DEG C, time 40min；
2）The good leech of pre-freeze is emitted in disk in individual layer, is put into vacuum freeze drier and freezes, first at -15 DEG C and -25
DEG C 30min is maintained respectively, then the central temperature of leech is reduced to -30 DEG C, freeze the moisture in leech；
3）Below 20Pa is evacuated to, -20 DEG C are then to slowly warm up in 2h, is incubated 1h, then 5 DEG C are risen in 1h,
Leech water content is set to drop to 6.5%；
4）30 DEG C are at the uniform velocity warming up in 2h, is incubated 1h, until leech water content drops to 1.68%.
Embodiment 3
The freeze drying process of the leech of the present embodiment comprises the following steps：
1）After leech is cleaned up, it is put into screw fast refreezer and carries out pre-freeze, pre-freezing temperature is -18 DEG C, time 30min；
2）The good leech of pre-freeze is emitted in disk in individual layer, is put into vacuum freeze drier and freezes, first at -15 DEG C and -25
DEG C 30min is maintained respectively, then the central temperature of leech is reduced to -32 DEG C, freeze the moisture in leech；
3）Below 20Pa is evacuated to, -20 DEG C are then to slowly warm up in 2h, is incubated 1h, then 5 DEG C are risen in 1h,
Leech water content is set to drop to 7%；
4）30 DEG C are at the uniform velocity warming up in 2h, is incubated 1h, until leech water content drops to 2.3%.
Claims (4)
1. a kind of freeze drying process of leech, it is characterised in that comprise the following steps：
1）After leech is cleaned up, it is put into screw fast refreezer and carries out pre-freeze, pre-freezing temperature is -18~-13 DEG C, the time 30
~45min；
2）The good leech sabot of pre-freeze is put into vacuum freeze drier and freezed, the central temperature of leech is reduced to -28~-
32 DEG C, freeze the moisture in leech；
3）Below 20Pa is evacuated to, -20 DEG C are then to slowly warm up in 2h, is incubated 0.5~1h, then risen in 1h
5℃；
4）30 DEG C are at the uniform velocity warming up in 2h, is incubated 0.5~1h, until leech water content drops to less than 3%.
2. the freeze drying process of leech according to claim 1, it is characterised in that：Step 2）Middle elder generation is in -15 DEG C and -25 DEG C points
30min is not maintained, and the central temperature of leech is then reduced to -30 DEG C again.
3. the freeze drying process of leech according to claim 1, it is characterised in that：Step 3）Middle leech water content drop to 8% with
Under.
4. the freeze drying process of leech according to claim 3, it is characterised in that：Step 2）Leech be emitted on disk in individual layer
In.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711147622.7A CN107661358A (en) | 2017-11-17 | 2017-11-17 | The freeze drying process of leech |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711147622.7A CN107661358A (en) | 2017-11-17 | 2017-11-17 | The freeze drying process of leech |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107661358A true CN107661358A (en) | 2018-02-06 |
Family
ID=61144589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711147622.7A Withdrawn CN107661358A (en) | 2017-11-17 | 2017-11-17 | The freeze drying process of leech |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107661358A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101008550A (en) * | 2007-01-10 | 2007-08-01 | 苏式兵 | Vacuum freeze-drying method for hirudo |
| CN101125126A (en) * | 2006-08-16 | 2008-02-20 | 丛繁滋 | Method for preparing medical freeze-dried powder (injection) preparation |
| CN101204402A (en) * | 2006-12-19 | 2008-06-25 | 上海水产大学 | Vacuum freezing and drying technology for leech |
| CN104256029A (en) * | 2014-09-03 | 2015-01-07 | 安徽恋尚你食品有限公司 | Leech and forsythia suspensa freeze-dried preserved raspberries and preparation method thereof |
-
2017
- 2017-11-17 CN CN201711147622.7A patent/CN107661358A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101125126A (en) * | 2006-08-16 | 2008-02-20 | 丛繁滋 | Method for preparing medical freeze-dried powder (injection) preparation |
| CN101204402A (en) * | 2006-12-19 | 2008-06-25 | 上海水产大学 | Vacuum freezing and drying technology for leech |
| CN101008550A (en) * | 2007-01-10 | 2007-08-01 | 苏式兵 | Vacuum freeze-drying method for hirudo |
| CN104256029A (en) * | 2014-09-03 | 2015-01-07 | 安徽恋尚你食品有限公司 | Leech and forsythia suspensa freeze-dried preserved raspberries and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104187871B (en) | Vacuum freeze drying processing method of shrimp meat | |
| CN1554292A (en) | Method for processing leisure seasoning dewatered fruit and vegetable | |
| CN103445227A (en) | Processing method of sliced freeze-dried abalone | |
| CN108157947A (en) | One kind is exempted to stew instant cubilose and preparation method thereof | |
| CN106070592A (en) | A kind of instant lyophilizing lotus seed production method | |
| CN101204402B (en) | Vacuum freezing and drying technology for leech | |
| CN102217695A (en) | Method for processing lonicera japonica tea by reducing loss of chlorogenic acid | |
| CN107050054B (en) | Processing technology of pilose antler | |
| CN107661358A (en) | The freeze drying process of leech | |
| CN100444753C (en) | Method of producing freeze dried abalone using fresh abalone | |
| CN105767138B (en) | Drying means rich in starch fruit and vegetable tablet | |
| CN106616576A (en) | Preparation method of dried pitaya fruits | |
| CN104824724B (en) | A kind of vacuum freeze-drying processing method of squid foot | |
| CN107997049A (en) | The preparation process of matrimony vine all-fruit powder | |
| CN107519206A (en) | A kind of Human plactnta freeze-dried powder preparation and preparation method thereof | |
| CN108300751A (en) | A kind of method of peanut meal extraction Peanut Polypeptide | |
| CN106174189A (en) | The preparation method of dried fruit | |
| CN103652898A (en) | Solid composition containing holothurian and chlorella pyrenoidosa and preparation method thereof | |
| CN107796183A (en) | Leech drying means | |
| CN106616575A (en) | Preparation method of dried jujube fruits | |
| US3419402A (en) | Process of preparing a freeze-dried gelled product | |
| JP3653354B2 (en) | How to dry food | |
| CN108576791B (en) | Preparation method of dried tremella product | |
| CN112617144A (en) | Processing technology of fruit and vegetable powder rich in cellulose | |
| CN108497390A (en) | A kind of matrimony vine milling method solving polysaccharides adhesiveness |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20180206 |