CN107648292A - A kind of concentrate of insect-expelling saligna injection liquid receives cream technique - Google Patents
A kind of concentrate of insect-expelling saligna injection liquid receives cream technique Download PDFInfo
- Publication number
- CN107648292A CN107648292A CN201710767613.1A CN201710767613A CN107648292A CN 107648292 A CN107648292 A CN 107648292A CN 201710767613 A CN201710767613 A CN 201710767613A CN 107648292 A CN107648292 A CN 107648292A
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- CN
- China
- Prior art keywords
- concentrate
- cream
- insect
- placing box
- injection liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Abstract
The present invention provides a kind of concentrate of insect-expelling saligna injection liquid and receives cream technique, air is completely cut off by stirring plus water and refrigerates the processing step received cream and detected, concentrate is carried out to receive cream processing, improve the receipts cream efficiency of concentrate, ensure the effect of the concentrate after receipts cream, and the viscosity of the concentrate after receiving cream is detected by rotary viscosimeter, facilitate the follow-up use of concentrate, it is inefficient and easily react with air and influence concentrate quality to solve the problems, such as to receive cream when insect-expelling saligna injection liquid concentrate receives cream.
Description
Technical field
The present invention relates to the concentrate of traditional Chinese medicine preparation field, more particularly to a kind of insect-expelling saligna injection liquid to receive cream
Technique.
Background technology
At present when preparing insect-expelling saligna injection liquid, due to carrying out extraction preparation to vernonia anthelmintica, concentration has been made
Liquid, but concentrate is using preceding needing concentrate carrying out receipts cream, but current receipts cream is operated in when receiving cream and easily received
Cream is incomplete, causes concentrate receipts cream ineffective, influences subsequently to use, and when receiving cream because concentrate and air occur instead
Should, the easy quality for influenceing concentrate.Therefore, receipts cream is inefficient when solving insect-expelling saligna injection liquid concentrate receipts cream and holds
Easily react with air and be just particularly important the problem of influenceing concentrate quality.
The content of the invention
In view of the above-mentioned problems of the prior art, it is an object of the invention to provide a kind of the dense of insect-expelling saligna injection liquid
Contracting liquid receives cream technique, and the processing step of cream-detection is received by stirring-plus water-isolation air-refrigeration, receipts cream is carried out to concentrate
Processing, the receipts cream efficiency of concentrate is improved, ensure the effect of the concentrate after receipts cream, solve insect-expelling saligna injection liquid concentration
Receive that cream is inefficient and the problem of influenceing concentrate quality of easily reacting with air when liquid receives cream.
The present invention provides a kind of concentrate of insect-expelling saligna injection liquid and receives cream technique, and the receipts cream technique step is as follows：
Step 1：Concentrate is placed in mixer and is stirred, and isothermal holding is carried out while stirring；
Step 2：Concentrate is placed in placing box, and to adding water for injection in placing box, reaches the concentration of concentrate
Predetermined value；
Step 3：To being passed through inert gas in placing box, the pressure in placing box is set to reach more than 50MPa；
Step 4：It is placed in freezer and refrigerates after placing box is sealed；
Step 5：The viscosity of concentrate is detected by rotary viscosimeter is put into the concentrate after cream in placing box, it is complete
Into receipts cream technique.
Further improvement is that：When carrying out isothermal holding to mixer in the step 1, ensure the temperature in mixer
In 20 ~ 30 DEG C.
Further improvement is that：The inert gas being passed through in the step 3 is nitrogen.
Further improvement is that：The temperature of freezer is maintained between 2 ~ 5 DEG C in described four, and cold preservation time is 12 hours.
Further improvement is that：Secondary stir is carried out to it before concentrate is put into rotary viscosimeter in the step 5
Mix.
The beneficial effects of the invention are as follows：The processing step of cream-detection is received by stirring-plus water-isolation air-refrigeration, it is right
Concentrate carries out receiving cream processing, improves the receipts cream efficiency of concentrate, ensures the effect of the concentrate after receipts cream, and passes through rotation
Formula viscosimeter detects to the viscosity of the concentrate after receiving cream, facilitates the follow-up use of concentrate.
Embodiment
In order to deepen the understanding of the present invention, below in conjunction with embodiment, the invention will be further described, the embodiment
It is only used for explaining the present invention, is not intended to limit the scope of the present invention..
Embodiment one
The concentrate for present embodiments providing a kind of insect-expelling saligna injection liquid receives cream technique, and the receipts cream technique step is as follows：
Step 1：Concentrate is placed in mixer and is stirred, and isothermal holding is carried out while stirring；
Step 2：Concentrate is placed in placing box, and to adding water for injection in placing box, reaches the concentration of concentrate
Predetermined value；
Step 3：To being passed through inert gas in placing box, the pressure in placing box is set to reach more than 50MPa；
Step 4：It is placed in freezer and refrigerates after placing box is sealed；
Step 5：The viscosity of concentrate is detected by rotary viscosimeter is put into the concentrate after cream in placing box, it is complete
Into receipts cream technique.
When carrying out isothermal holding to mixer in the step 1, ensure the temperature in mixer in 27 DEG C.The step
The inert gas being passed through in rapid three is nitrogen.The temperature of freezer is maintained between 2.5 DEG C in described four, and cold preservation time is 12 small
When.Secondary agitation is carried out to it before concentrate is put into rotary viscosimeter in the step 5.
Embodiment two
The concentrate for present embodiments providing a kind of insect-expelling saligna injection liquid receives cream technique, and the receipts cream technique step is as follows：
Step 1：Concentrate is placed in mixer and is stirred, and isothermal holding is carried out while stirring；
Step 2：Concentrate is placed in placing box, and to adding water for injection in placing box, reaches the concentration of concentrate
Predetermined value；
Step 3：To being passed through inert gas in placing box, the pressure in placing box is set to reach more than 50MPa；
Step 4：It is placed in freezer and refrigerates after placing box is sealed；
Step 5：The viscosity of concentrate is detected by rotary viscosimeter is put into the concentrate after cream in placing box, it is complete
Into receipts cream technique.
When carrying out isothermal holding to mixer in the step 1, ensure the temperature in mixer in 20 DEG C.The step
The inert gas being passed through in rapid three is nitrogen.The temperature of freezer is maintained between 2 DEG C in described four, and cold preservation time is 12 hours.
Secondary agitation is carried out to it before concentrate is put into rotary viscosimeter in the step 5.
Embodiment three
The concentrate for present embodiments providing a kind of insect-expelling saligna injection liquid receives cream technique, and the receipts cream technique step is as follows：
Step 1：Concentrate is placed in mixer and is stirred, and isothermal holding is carried out while stirring；
Step 2：Concentrate is placed in placing box, and to adding water for injection in placing box, reaches the concentration of concentrate
Predetermined value；
Step 3：To being passed through inert gas in placing box, the pressure in placing box is set to reach more than 50MPa；
Step 4：It is placed in freezer and refrigerates after placing box is sealed；
Step 5：The viscosity of concentrate is detected by rotary viscosimeter is put into the concentrate after cream in placing box, it is complete
Into receipts cream technique.
When carrying out isothermal holding to mixer in the step 1, ensure the temperature in mixer in 30 DEG C.The step
The inert gas being passed through in rapid three is nitrogen.The temperature of freezer is maintained between 5 DEG C in described four, and cold preservation time is 12 hours.
Secondary agitation is carried out to it before concentrate is put into rotary viscosimeter in the step 5.
Claims (5)
1. a kind of concentrate of insect-expelling saligna injection liquid receives cream technique, it is characterised in that：The receipts cream technique step is as follows：
Step 1：Concentrate is placed in mixer and is stirred, and isothermal holding is carried out while stirring；
Step 2：Concentrate is placed in placing box, and to adding water for injection in placing box, reaches the concentration of concentrate
Predetermined value；
Step 3：To being passed through inert gas in placing box, the pressure in placing box is set to reach more than 50MPa；
Step 4：It is placed in freezer and refrigerates after placing box is sealed；
Step 5：The viscosity of concentrate is detected by rotary viscosimeter is put into the concentrate after cream in placing box, it is complete
Into receipts cream technique.
2. a kind of concentrate of insect-expelling saligna injection liquid as claimed in claim 1 receives cream technique, it is characterised in that：The step
When carrying out isothermal holding to mixer in rapid one, ensure the temperature in mixer in 20 ~ 30 DEG C.
3. a kind of concentrate of insect-expelling saligna injection liquid as claimed in claim 1 receives cream technique, it is characterised in that：The step
The inert gas being passed through in rapid three is nitrogen.
4. a kind of concentrate of insect-expelling saligna injection liquid as claimed in claim 1 receives cream technique, it is characterised in that：Described four
The temperature of middle freezer is maintained between 2 ~ 5 DEG C, and cold preservation time is 12 hours.
5. a kind of concentrate of insect-expelling saligna injection liquid as claimed in claim 1 receives cream technique, it is characterised in that：The step
Secondary agitation is carried out to it before concentrate is put into rotary viscosimeter in rapid five.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710767613.1A CN107648292A (en) | 2017-08-31 | 2017-08-31 | A kind of concentrate of insect-expelling saligna injection liquid receives cream technique |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710767613.1A CN107648292A (en) | 2017-08-31 | 2017-08-31 | A kind of concentrate of insect-expelling saligna injection liquid receives cream technique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107648292A true CN107648292A (en) | 2018-02-02 |
Family
ID=61128034
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710767613.1A Pending CN107648292A (en) | 2017-08-31 | 2017-08-31 | A kind of concentrate of insect-expelling saligna injection liquid receives cream technique |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107648292A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1242203A (en) * | 1998-07-21 | 2000-01-26 | 邢炳荣 | Pure traditional Chinese medicine concentrated capsule for treating hepatitis B |
| CN1895317A (en) * | 2006-06-24 | 2007-01-17 | 太原华卫药业有限公司 | Preparation of safflower injection |
| CN103735588A (en) * | 2014-01-26 | 2014-04-23 | 芜湖杨燕制药有限公司 | Vernonia anthelmintica wild injection and preparation method thereof |
| CN104107211A (en) * | 2014-07-29 | 2014-10-22 | 黑龙江珍宝岛药业股份有限公司 | Preparation method of astragalosides extract |
| CN105832659A (en) * | 2016-04-29 | 2016-08-10 | 芜湖杨燕制药有限公司 | Production technology of traditional Chinese medicine injection |
-
2017
- 2017-08-31 CN CN201710767613.1A patent/CN107648292A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1242203A (en) * | 1998-07-21 | 2000-01-26 | 邢炳荣 | Pure traditional Chinese medicine concentrated capsule for treating hepatitis B |
| CN1895317A (en) * | 2006-06-24 | 2007-01-17 | 太原华卫药业有限公司 | Preparation of safflower injection |
| CN103735588A (en) * | 2014-01-26 | 2014-04-23 | 芜湖杨燕制药有限公司 | Vernonia anthelmintica wild injection and preparation method thereof |
| CN104107211A (en) * | 2014-07-29 | 2014-10-22 | 黑龙江珍宝岛药业股份有限公司 | Preparation method of astragalosides extract |
| CN105832659A (en) * | 2016-04-29 | 2016-08-10 | 芜湖杨燕制药有限公司 | Production technology of traditional Chinese medicine injection |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180202 |
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| RJ01 | Rejection of invention patent application after publication |