CN107596173A - A kind of Chinese medicine for treating anal fissure, perianal abscess - Google Patents

A kind of Chinese medicine for treating anal fissure, perianal abscess Download PDF

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CN107596173A
CN107596173A CN201710986933.6A CN201710986933A CN107596173A CN 107596173 A CN107596173 A CN 107596173A CN 201710986933 A CN201710986933 A CN 201710986933A CN 107596173 A CN107596173 A CN 107596173A
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parts
urine
chinese medicine
anal fissure
treatment
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张爱平
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Abstract

The invention belongs to pharmaceutical technology field, and in particular to a kind of Chinese medicine for treating anal fissure, perianal abscess.Using plantain seed, astragalus root, the stem pith of the rice-paper plant, rush, Lygodium japonicum, rhizoma alismatis, Poria cocos, lophatherum gracile, rhizoma atractylodis macrocephalae as raw material.The present invention has therapeutic effect good, the advantages that recurrence.

Description

A kind of Chinese medicine for treating anal fissure, perianal abscess
Technical field
The invention belongs to pharmaceutical technology field, and in particular to a kind of Chinese medicine for treating anal fissure, perianal abscess.
Background technology
Mixed hemorrhoid is most common anus benign disease.Support structure, veniplex and the arteriovenous anastomosis Zhi Fasheng of anus pad It is internal piles that pathology, which is sexually revised or shifted,;The pathological dilatation or thrombosis of dentate line distal side venae subcutaneae clump are external piles;Internal piles Mutually merged as mixed hemorrhoid by the external piles of abundant veniplex ramus anastomoticus and corresponding site.The main clinical manifestation of mixed hemorrhoid To have blood in stool, hemorrhoid abjection, pain and itch, be a common disease, frequently-occurring disease.Operative treatment is the important side of effective treatment mixed hemorrhoid Method, especially when effect of conservative treatment is dissatisfied, hemorrhoid abjection is serious, ligation treatment fails, surgery excision is its best treatment Method.The traditional Chinese medical science is referred to as hemorrhoid, and card type is based on damp and hot lower card.
Anal fissure is the ischemic ulcer formed after the following anal canal skin slabbing of dentate line is hindered, is more common in blue or green, a middle-aged person.Its side To parallel with the anal tube longitudinal axis, 0.5 to 1.0 centimetre is about, in fusiformis or ellipse, often causes crissum severe pain, constipation and bleeding.Hand Art is one of critical treatment method of anal fissure.The traditional Chinese medical science is referred to as anal fissure disease, and card type is common with damp and hot lower card, also visible thermojunction intestines Dry card.
The acute festering type infection that perianal abscess is crissum soft tissue or its peripheral clearance occurs, it is common with male, it is more Send out the person between twenty and fifty in 20 to 40 years old.Onset urgency, sharp ache are characterized in, anal fistula can be formed after abscess ulceration or incision.It is clinical In, once clarifying a diagnosis, then need row perianal abscess onestage radical operation as early as possible.The traditional Chinese medical science is referred to as anus carbuncle, and card type is with damp-heat accumulation Based on.
Anal fistula is anal tube or rectum and the granular pipeline of anal skin identical, there is internal orifice, fistula and collar extension three parts group Into, can be fallen ill in any age, be more common in male adults, its feature for do not recover for a long time or intercurrent relapse make.Anal fistula often with Collar extension flows out a small amount of purulence, courage and uprightness, wants symptom based on mucus sexual secretion, and larger upper fistula mouth can also have excrement and gas row Go out.Due to the stimulation of secretion, anus area is moist, itch, can form eczema sometimes.When collar extension heals, there is abscess in fistula Formed, obvious pain can be felt, while can also be with the general infection symptom such as heating, shiver with cold, weak, now must egilops Or incision and drainage.Anal fistula is often difficult to self-healing, does not treat meeting recurrent exerbation and forms rectum anal tube perianal abscess, therefore most It is both needed to operative treatment.The traditional Chinese medical science is referred to as anus leakage, and card type is based on damp and hot lower card.
In clinic, operation is treatment mixed hemorrhoid, anal fissure, perianal abscess, the maximally effective treatment method of anal fistula.It is however, postoperative Because a variety of causes usually causes urination not smooth or is unable to voluntary micturition, the i.e. retention of urine.It is postoperative common concurrent that it has turned into its Disease[1], the incidence of disease is up to 52%.The retention of urine brings very big pain to these patients, has influence on postoperative rehabilitation, and then have impact on hand Art curative effect.
The category of retention of urine category motherland's medical science " retention of urine ".Interpretation of the cause, onset and process of an illness category water stores bladder, disturbance in qi transformation.In clinical practice, I Sum up mixed hemorrhoid (syndrome of dampness-heat diffusing downward), anal fissure (syndrome of dampness-heat diffusing downward), perianal abscess (syndrome of accumulated dampness-heat), anal fistula (under damp and hot Note card) postoperative urine retention etiology and pathogenesis:Operation wound consumption hinders vigour, and vigour is damaged, in addition damp and hot to be reluctant to leave, it is impossible to dispels it, heat For yang pathogens, gas consumption hinders Tianjin, the deficiency of vital energy then row Tianjin miopragia, wet Jiao that stops, damp being a kind of YIN pathogen, blocks mechanism of qi, causes functioning of bladder not Profit, therefore see the retention of urine.Therefore think that mixed hemorrhoid, anal fissure, perianal abscess, anal fistula postoperative urine retention category vigour more are deficient, and folder is damp and hot.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine for treating anal fissure, perianal abscess, to solve above-mentioned to deposit in the prior art The problem of.
To achieve the above object, the technical solution adopted in the present invention is:
A kind of Chinese medicine for treating anal fissure, perianal abscess, include the component of following parts by weight:
10~40 parts of plantain seed, 10~40 parts of astragalus root, 5~15 parts of the stem pith of the rice-paper plant, 5~20 parts of rush, Lygodium japonicum 5~15 Part, 5~20 parts of rhizoma alismatis, 5~20 parts of Poria cocos, 5~15 parts of lophatherum gracile, 5~20 parts of rhizoma atractylodis macrocephalae.
In the component of medicine of the present invention:Plantain seed nature and flavor are sweet, light, are slightly cold.Return lung, liver, kidney, bladder warp.Reducing fever and causing diuresis;Ooze Wet antidiarrheal.Main difficult urination, oedema turgor;Such as《This is through meeting original》Sayed:" specially ventilation, water-filling road, thin sharp bladder are wet for plantain seed Heat ".Astragalus root:Nature and flavor are sweet, temperature.Return lung, the spleen channel.Invigorating middle warmer and replenishing QI.For treatment deficiency of vital energy weak, anorexia and loose stool.Such as《Pearl sac》Sayed: " the sweet Wen Chunyang of the Radix Astragali, it is with having five:It is insufficient to mend all void, one;Beneficial vigour, two;Strong taste, three;…”.Radix glycyrrhizae:Nature and flavor It is sweet, put down.The thoughts of returning home, lung, spleen, stomach.Invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.The stem pith of the rice-paper plant:Nature and flavor It is sweet, light, it is slightly cold.Attach to the lung and stomach meridians.Reducing fever and causing diuresis, lower breast of ventilating.For damp-warm syndrome urine, the puckery pain of gonorrhoea, oedema oliguria.Rush: Nature and flavor are sweet, light, are slightly cold.The thoughts of returning home, lung, small intestinl channel.Clearing away the heart-fire, diuresis.For vexed insomnia, the puckery pain of oliguria.Lygodium japonicum:Nature and flavor It is sweet, salty, tremble with fear.Return bladder, small intestinl channel.Eliminating dampness and heat, treating stranguria analgesic.It is puckery for heat gonorrhea, sand leaching, urolithiasis, blood strangury, cream leaching, urethra Bitterly.Rhizoma alismatis:Nature and flavor are sweet, tremble with fear.Return kidney, bladder warp.Diuresis, clearing away damp-heat.For difficult urination, oedema turgor, oliguria of having loose bowels.Fu Siberian cocklebur:Nature and flavor are sweet, light, put down.The thoughts of returning home, lung, spleen, kidney channel.Clearing damp and promoting diuresis, invigorating the spleen calming heart.For oedema oliguria, spleen eating less, loose stool Diarrhea.Lophatherum gracile:Nature and flavor are sweet, light, tremble with fear.The thoughts of returning home, stomach, small intestinl channel.Clearing heat and relieving fidgetness, diuresis.For pyreticosis polydipsia, hot urination leaching Bitterly.Rhizoma atractylodis macrocephalae:It is bitter in taste, sweet, temperature.Returns spleen, stomach.Strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect.For spleen eating less, abdominal distention diarrhea, phlegm and retained fluid Feel dizzy and heart palpitations, oedema, spontaneous perspiration, fetal irritability.Rhizoma atractylodis macrocephalae invigorating the spleen, and stomach, it is antiabortive.For spleen eating less, diarrhea loose stool, fetal irritability.
In prescription of the present invention:Plantain seed reducing fever and causing diuresis, astragalus root tonifying Qi diuresis, close and gather the work(of heat-clearing tonifying Qi diuresis, be altogether Monarch drug in a prescription;Lygodium japonicum, rhizoma alismatis, lophatherum gracile, the stem pith of the rice-paper plant, four flavour of a drug are sweet cold, aid in plantain seed reducing fever and causing diuresis.Rhizoma atractylodis macrocephalae, strengthening the spleen and replenishing qi profit Urine, astragalus root temperature compensation vigour being aided in, diuresis, five medicines are minister, and rush, Poria cocos, nature and flavor are sweet, flat, clearing damp and promoting diuresis, invigorating the spleen tonifying Qi, For adjutant.All medicine energy clearing heat and promoting diuresis, tonifying Qi row Tianjin, mechanism of qi is adjusted, makes functioning of bladder functional rehabilitation as usual, so as to reach tonifying Qi profit The effect of urine.
Modern pharmacological research also shows:The Radix Astragali mainly contains glucoside, polysaccharide, amino acid and trace element etc., has enhancing Body immune function, diuresis etc. act on.The how mucous matter of plantain seed, butanedioic acid, Chinese herbaceous peony enol, adenine, choline, plantain seed Alkali, fat oil, vitamin A and B etc., there is notable diuresis.Rhizoma alismatis, the stem pith of the rice-paper plant, rhizoma atractylodis macrocephalae, rush, Poria cocos have diuresis work With.
Chinese medicine of the present invention is cheap and convenient to take, is worth the popularization and application in clinic, has good effect, has no side effect The advantages that.
Further to show the therapeutic effect of medicine of the present invention, it is as follows that the Chinese medicine is used for clinical situation:In January, 2013 To 110, wherein mixed hemorrhoid 26 during in January, 2016, have been treated, anal fissure 28, perianal abscess 30, anal fistula 26, treat Effect satisfaction.
In January, 2014 to during in January, 2016, we use the design method of random controls single blind trial, will meet The subject of standard is with 1:1 ratio is assigned randomly to treatment group's (medicine of the present invention), control group (Longbishu Jiaonang.), often Group case load is 40 (mixed hemorrhoid 10, anal fissure 10, perianal abscess 10, anal fistula 10).Oral institute of the present invention for the treatment of group State drug therapy, the oral Longbishu Jiaonang. treatment of control group, two groups of patient's urine of observation, symptom, sign and residual urine volume Change, statistics improvement rate, cure rate.Zi Liao ﹙ as two groups of Yi are shown in Table 1 ﹚ contrasts, not statistically significant (P>0.05), having can Compare property.
Table 1:Patient data's statistical form
Diagnosis basis:Mixed hemorrhoid diagnoses reference《Hemorrhoid clinical diagnosis and treatment guide (2006 editions)》[3];Anal fissure, perianal abscess, anal fistula With reference to national higher medical institution programming textbook《Proctology of traditional Chinese medicine》(2011 editions)[4]Formulate;The retention of urine is with reference to national traditional Chinese medicine Management board《Chinese medical disease Standardization of diagnosis and curative effect》[5]In " retention of urine " diagnostic criteria formulate.
1. mixed hemorrhoidSyndrome of dampness-heat diffusing downward:A. clinical manifestation:Color of having blood in stool is scarlet, and amount is more.Anus swells beyond the region of objective existence de-, swelling, scorching hot pain Or there is taste water.Just dry or half congealed, scanty drak urine.B. sign:Red tongue body, yellow and greasy fur, slippery and rapid pulse.
2. anal fissureSyndrome of dampness-heat diffusing downward:A. clinical manifestation:Pain when just, defecation is not well, rectal tenesmus, when have mucus blood.B. body Sign:The visible shuttle breach of anal tube.Red tongue body, thick,yellow and greasy fur, slippery and rapid pulse.
3. perianal abscessSyndrome of accumulated dampness-heat:A. clinical manifestation:Crissum swells and ache, and unbearably, with fever with aversion to cold, dry, just does or half congealed, Scanty drak urine.B. sign:Purple grass oil.There is fluctuation by it.Red tongue body, yellow tongue fur, slippery and rapid pulse.
4. anal fistulaSyndrome of dampness-heat diffusing downward:A. clinical manifestation:Crissum swells and ache, and leak down fester, and yellowish-white stiff, defecation is not smooth, scanty drak urine. B. sign:Touch can be laid one's hand on and streak thing leads in anus.Red tongue body, yellow and greasy fur, slippery.
5. the retention of urine:A. clinical manifestation:Difficult urination, drop is not smooth, or urine occlusion is obstructed, and urethra is without puckery pain, underbelly Turgor.B. sign:The obvious voiced sound of bladder area percussion.C. auxiliary examination:B ultrasound prompts residual urine.
Include, Excluded cases standard
Include case standard:1. meeting the diagnostic criteria of the retention of urine and through psychological counseling and physics inducement, nonresponder;2. accord with Close mixed hemorrhoidSyndrome of dampness-heat diffusing downward, anal fissureSyndrome of dampness-heat diffusing downward, perianal abscessSyndrome of accumulated dampness-heat, anal fistulaSyndrome of dampness-heat diffusing downwardDiagnostic criteria;3. the age:18 years old >=and≤65 Year, men and women are unlimited;4. patient signs informed consent form.
Excluded cases standard:
1. the gestational period and women breast-feeding their children;2. allergic constitution person;3. having inflammation in urinary system, tumour, calculus, obstruction person, have Hypertrophy of the prostate person;4. merge intentionally, the cerebrovascular, liver, lung, the severe primary disease patient such as kidney and hemopoietic system;5. liver kidney function Can abnormal person;, need to the person of analgesia 6. postoperative pain is obvious;7. mental patient;
8. this experimenter can not be completed on request.
Efficacy assessment standard:With reference to State Administration of Traditional Chinese Medicine《Chinese medical disease Standardization of diagnosis and curative effect》[5]In " retention of urine " treatment Evaluation criteria is imitated to formulate.
Cure:Urine is unobstructed, and symptom and sign disappear.Bladder color ultrasound is shown:Bladder is without residual urine volume;
Take a turn for the better:Symptom and sign improve.Bladder color ultrasound is shown:Residual urine volume reduces >=1/2;
It is not cured:Symptom is unchanged, as patient tells that small distention and fullness in the abdomen is obvious and the flat navel person in percussion filling of bladder face in treatment phase, depending on Not to be cured, parallel catheterization.
The application method of the present invention:Take plantain seed 20g, astragalus root 20g, stem pith of the rice-paper plant 10g, rush 15g, Lygodium japonicum 15g, pool Rush down 12g, Poria cocos 10g, lophatherum gracile 12g, rhizoma atractylodis macrocephalae 15g.By the decocting of said medicine routine or granule, pill are prepared into, often Day one, morning and evening one after each meal.Control group:Longbishu Jiaonang., one time 3, warm water delivery service (50ml/ times), 2 times a day.3 days For a course for the treatment of, curative effect is observed after a course for the treatment of.
Statistical method:Statistics inputs SPSS13.0 statistical softwares, and wherein enumeration data is examined using x2, metering Data is examined using t.Treatment results are shown in Table 3.
Table 2:Treatment results count
As can be seen from Table 2, control group total effective rate is 67.5%, and treatment group's total effective rate is 85.0%, two groups of cases Statistically significant (the p of total effective rate comparing difference after treatment<0.05), illustrate that treatment group's curative effect is better than control group.
Under be classified as the model case that patient takes medicine of the present invention:
1. Mr. Wang, female, 32 years old, on May 9th, 2014, our hospital's anorectum department was in hospital mixed hemorrhoid (syndrome of dampness-heat diffusing downward) patient, readme Illness:Mixed hemorrhoid dysuria after prostatectomy is suppressed swollen 3 hours with underbelly, is looked into:Bladder voiced sound circle three horizontal finger under navel.Examine for:The traditional Chinese medical science is examined It is disconnected:The postoperative retention of urine of hemorrhoid (vigour is deficient, and folder is damp and hot) doctor trained in Western medicine diagnosis:Mixed hemorrhoid postoperative urine retention.Take medicine 1 of the present invention The state of an illness slows down after the individual course for the treatment of, continues to take 1 course for the treatment of, illness is disappeared, and follow-up is not recurred so far.
2. Zhang, female, 50 years old, on December 1st, 2015, our hospital's anorectum department was in hospital anal fistula (syndrome of dampness-heat diffusing downward) patient, from State illness:Dysuria after prostatectomy is freely suppressed swollen 6 hours with underbelly, is looked into:Bladder voiced sound circle three horizontal finger under navel.Examine for:Tcm diagnosis: Anus leaks the postoperative retention of urine (vigour is deficient, and folder is damp and hot) doctor trained in Western medicine diagnosis:Anal fistula postoperative urine retention.Take medicine 1 of the present invention Illness is disappeared after the course for the treatment of, and follow-up is not recurred so far.
3. Zhang, man, 46 years old, on August 10th, 2015, our hospital's anorectum department was in hospital perianal abscess (syndrome of accumulated dampness-heat) patient, Readme illness:Dysuria after prostatectomy is freely suppressed swollen 5 hours with underbelly, is looked into:Bladder voiced sound circle four horizontal finger under navel.Examine for:The traditional Chinese medical science is examined It is disconnected:The postoperative retention of urine of anus carbuncle (vigour is deficient, and folder is damp and hot) doctor trained in Western medicine diagnosis:Perianal abscess postoperative urine retention.Take of the present invention Illness is disappeared after 1 course for the treatment of of medicine, and follow-up is not recurred so far.
4. Mr. Li, male, 38 years old, on March 15th, 2014, our hospital's anorectum department was in hospital anal fissure (syndrome of dampness-heat diffusing downward) patient, from State illness:The postoperative urination of mixed hemorrhoid hemorrhoid is owed unobstructed and suppressed swollen 6 hours with underbelly, looks into:Bladder voiced sound circle two horizontal finger under navel.Examine for: Tcm diagnosis:The postoperative retention of urine of anal fissure disease (vigour is deficient, and folder is damp and hot) doctor trained in Western medicine diagnosis:Anal fissure postoperative urine retention.Take the present invention Illness is disappeared after described 1 course for the treatment of of medicine, and follow-up is not recurred so far.
Embodiment
Embodiment 1:
Weigh the Chinese medicine of following parts by weight:Plantain seed 10g, astragalus root 10g, stem pith of the rice-paper plant 5g, rush 5g, Lygodium japonicum 5g, Rhizoma alismatis 5g, Poria cocos 5g, lophatherum gracile 5g, rhizoma atractylodis macrocephalae 5g.
The application method of medicine described in the present embodiment:By the decocting of said medicine routine or granule, pill are prepared into, it is excellent It is granule to select formulation, and efficacy evaluation treats 30 patients, and treatment results are healing 18, are taken a turn for the better 6, not more 6, always effectively Rate reaches 80.0%.
Embodiment 2:
Weigh the Chinese medicine of following parts by weight:Plantain seed 20g, astragalus root 20g, stem pith of the rice-paper plant 10g, rush 15g, Lygodium japonicum 12g, rhizoma alismatis 12g, Poria cocos 10g, lophatherum gracile 12g, rhizoma atractylodis macrocephalae 15g.
Medicine described in the present embodiment equally treats 40 patients using above-mentioned treatment method, efficacy evaluation, and treatment results are 30 are cured, is taken a turn for the better 5, not more 5, total effective rate reaches 87.5%.
Embodiment 3:
Weigh the Chinese medicine of following parts by weight:Plantain seed 40g, astragalus root 40g, stem pith of the rice-paper plant 15g, rush 20g, Lygodium japonicum 15g, rhizoma alismatis 20g, Poria cocos 20g, lophatherum gracile 15g, rhizoma atractylodis macrocephalae 20g.
Medicine described in the present embodiment equally treats 35 patients using above-mentioned treatment method, efficacy evaluation, and treatment results are 27 are cured, is taken a turn for the better 3, not more 5, total effective rate reaches 85.7%.
Embodiment 4:
Weigh the Chinese medicine of following parts by weight:Plantain seed 10g, astragalus root 30g, stem pith of the rice-paper plant 12g, rush 10g, Lygodium japonicum 10g, rhizoma alismatis 18g, Poria cocos 20g, lophatherum gracile 10g, rhizoma atractylodis macrocephalae 5g.
Medicine described in the present embodiment equally treats 32 patients using above-mentioned treatment method, efficacy evaluation, and treatment results are 26 are cured, is taken a turn for the better 2, not more 4, total effective rate reaches 87.5%.

Claims (1)

1. a kind of Chinese medicine for treating anal fissure, perianal abscess, it is characterized in that, include the components of following parts by weight:
10~40 parts of plantain seed, 10~40 parts of astragalus root, 5~15 parts of the stem pith of the rice-paper plant, 5~20 parts of rush, 5~15 parts of Lygodium japonicum, pool Rush down 5~20 parts, 5~20 parts of Poria cocos, 5~15 parts of lophatherum gracile, 5~20 parts of rhizoma atractylodis macrocephalae.
CN201710986933.6A 2017-10-20 2017-10-20 A kind of Chinese medicine for treating anal fissure, perianal abscess Withdrawn CN107596173A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1269234A (en) * 1999-04-07 2000-10-11 林嘉峰 Chiense medicine for treating various piles
DE202008005052U1 (en) * 2008-04-09 2008-08-07 Eckardt, Rainer, Dr.med. Care and healing oil for the treatment of dry, miraculously, heavily used and radiation-damaged skin
CN105617123A (en) * 2016-04-08 2016-06-01 李志鹏 Traditional Chinese medicine for treating qi-deficiency and damp-heat type urinary retention after anus operation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1269234A (en) * 1999-04-07 2000-10-11 林嘉峰 Chiense medicine for treating various piles
DE202008005052U1 (en) * 2008-04-09 2008-08-07 Eckardt, Rainer, Dr.med. Care and healing oil for the treatment of dry, miraculously, heavily used and radiation-damaged skin
CN105617123A (en) * 2016-04-08 2016-06-01 李志鹏 Traditional Chinese medicine for treating qi-deficiency and damp-heat type urinary retention after anus operation

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