CN107589160A - A kind of preparation method and application of the ternary nano composite material based on MOF - Google Patents
A kind of preparation method and application of the ternary nano composite material based on MOF Download PDFInfo
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Abstract
It is used for the application for detecting enantiomers of chiral drugs the invention discloses a kind of preparation method of ternary nano composite material based on MOF and based on the composite, belongs to nano material, Metal-organic frame, analytical chemistry and chiral sensing detection technical field.It, which has main steps that, first prepares graphite-phase C3N4Carried metal organic framework [(AgL) ClO4] n nanocrystals, continuously add KBr in-situ reducing and the ternary nano composite material g C based on MOF are made3N4@ MOF@ Ag.The sensor built using the composite, Sensitive Detection enantiomers of chiral drugs.
Description
Technical field
The present invention relates to a kind of preparation method of ternary nano composite material based on MOF and based on composite electricity
Chemical sensitisation detects the application of penicillamine enantiomer, belongs to nano material, catalysis technique, Metal-organic frame material technology neck
Domain.
Background technology
Metal-organic framework thing (MOFs) is by metal ion or metal ion cluster and multiple tooth organic ligand small molecule, is led to
Cross the crystalline substance with regular duct and aperture, rule space topology and periodic network structure that coordinate bond driving force is self-assembly of
Body material.Compared with other conventional porous materials, not only the specific surface area ratio with superelevation and porosity, heat are steady for MOFs materials
The features such as qualitative good, and with pore passage structure is homogeneous, duct includes open and periodicity unsatuated metal site, endoporus and table
Face can function sex modification, crystalline size and geometry can design regulation and control etc. the incomparable new features of other traditional materials.Mesh
Before, the exploitation of the material just with inorganic chemistry, Coordinative Chemistry, organic chemistry, physical chemistry, supramolecular chemistry, materials chemistry, life
The ambit such as thing chemistry and crystal engineering intersects.So far, MOFs correlations exploitation is incremented by again with index every year,
Design synthesis, structure and performance study achievement rapidly increase, and the material is in chemical industry and other technical fields, for example, being catalyzed, dividing
From, magnetic, photoelectricity, gas storage and sensing etc., show wide application prospect.
Nano material is at least one-dimensional for 1-100nm or the material that is assembled into by its elementary cell in three dimensions.Cause
The dimension of its nanometer of category, nano material show the characteristic that macroscopic material can not compare.Application potential huge MOFs
The process of nanosizing preparation is urged it into, so as to greatly improve the specific surface area of the material, increase its textural porosity, is disappeared
Remove and reduce the limitation in mass transport process, so as to increase its catalytic activity and reduce its response in sensor application program
Time, by it feature be combined with high sensitivity.By MOFs crystalline nanometrics and compound with other functional materials
Through a focus developing way as current MOFs chemistry.
In general, it is control and regulation chemical reaction that nanometer MOFs, which synthesizes most easy method, that is, passes through control
Physical parameter regulates and controls its growth, including addition modifying agent and surfactant, controls ratio and the reaction time of reactant
And temperature.Also occur many new methods recently, for example, heating of ultrasonic wave or microwave (MW) auxiliary etc..
Class graphite phase carbon nitride g-C3N4, be with C, N it is spaced, take sp2 hydridization formed σ key connections form
Hexagon covalent compound, each C and N atoms in structure are mutually bonded with single electron p tracks, form big pi bond；g-
C3N4Chemical stability and heat endurance are high, raw material is cheap and easy to get, preparation technology is simple, photodissociation organic pollution, photocatalytic water system
The technical fields such as hydrogen, fuel cell, catalyst carrier have shown excellent performance.
Noble metal nanometer material enjoys the favor of researchers with the property of its superior light, electricity, magnetic etc..At present
Conventional metal nano material includes gold, silver, copper, platinum etc., is widely used in the structure of electrochemical sensor.Wherein silver is received
Rice material possess cheap price, stronger adsorption capacity, good biocompatibility, efficient electro catalytic activity and quickly
The incomparable special nature of other nano materials such as electron transfer rate, pays close attention to more and more widely so as to receive.
There is significance difference for pharmacological activity, distribution, metabolic process and the toxicity of enantiomers of chiral drugs in human body etc.
Different, its significant difference behavior is mainly manifested in：1. a kind of enantiomer in two enantiomers has a pharmacological activity, and another pharmacology
Activity is not notable.For example, the antiinflammatory action and analgesic activity of S- ketorolac medicines are 60 times 230 times of R- ketorolacs respectively；S-
The antiinflammatory action of naproxen is 35 times of R-NAP.2. the pharmacological action of two kinds of structure phases of chiral drug is completely different.Example
Such as, R- tetramisoles are antidepressants, and S- is that tetramisole is dehelminthization medicine, and dextropropoxyphene is a kind of analgestic, and left-handed
Dextropropoxyphene is a kind of antitussive.3. a kind of structure of enantiomer mutually has pharmacological activity, and another kind produces serious side effect.Example
Such as, the ketamine as non-barbiturates central depressant, its S- configuration has anesthesia and analgesic activity, and R- configurations have excitement
Maincenter causes mental symptom；Although two enantiomers of Thalidomide have identical sedation, but S- structures are met causes abnormal resistance
Effect.In recent years, in order to solve some problems caused by racemic modification medicine, many developed countries constantly promulgate relevant hand
The guidance quality guide or policy of property drug development.In the U.S., food and the Drug Administration (FICA) of chiral drug require to apply
The chiral component and respective pharmacological action of enantiomer that contains in person's mandatory declaration novel drugs, clinical effectiveness and toxicity, and taste
Examination separates stereoisomer therein.Canada, European Community etc. have also formulated the policy of correlation.
Develop g-C3N4, metal-organic framework thing nano material and load the expensive particle trielement composite material of nanometer preparation
Method, and have great importance for detecting identification chiral drug.
The content of the invention
One of technical assignment of the present invention is to make up the deficiencies in the prior art, there is provided a kind of ternary based on MOF is received
The preparation method of nano composite material, preparation technology used in this method is simple, and energy consumption of reaction is low, has prospects for commercial application.
The two of the technical assignment of the present invention are to provide the purposes of the ternary nano composite material based on MOF, will be based on
MOF ternary nano composite material is used for the content of efficient detection chiral drug penicillamine enantiomer, the detecting instrument cost is low,
Analysis efficiency is high, easy to operate, and operating technology requires low.
Technical scheme is as follows：
1. a kind of preparation method of the ternary nano composite material based on MOF, step are as follows：
（1）Prepare g-C3N4@MOF nanocrystals
By 0.34-0.45 g AgClO4With 0.068-0.090 g graphite phase carbon nitrides g-C3N41-1.5 mL water is dissolved in, obtains g-
C3N4@Ag (I) aqueous solution；0.45 g ligand Ls are dissolved in 1-2 mL methanol, obtain the methanol solution of ligand L；By g-C3N4@Ag
(I) aqueous solution and the shaking of the methanol solution of ligand L are blended, and stand 2-3 h, centrifuge and washed 3 times with methanol, g- is made
C3N4@MOF nanocrystals；
（2）Prepare g-C3N4@MOF@Ag nano composite materials
By obtained g-C3N4@MOF nanocrystals, add 4-6 mL, the KBr ethanol solutions that mass fraction is 5 %, mix,
24 h are stored at room temperature, centrifuges and is washed 3 times with ethanol, 70 DEG C of dryings, g-C is made3N4@MOF@Ag nano composite materials,
That is the ternary nano composite material based on MOF.
Step（1）Described in graphite phase carbon nitride g-C3N4, preparation method is as follows：
3g dicyandiamides are put into crucible, are compacted, air atmosphere in tube furnace is placed in and calcines, heating rate is 2.3 DEG C/min, is risen to
500 DEG C, insulation 4h, natural cooling, are made graphite phase carbon nitride g-C3N4。
Step（1）Described in ligand L, structural formula is as follows：
The preparation process of ligand L is as follows：
Under stirring condition, 0.10 mol 1,2- ethylenediamines are mixed with 0.20 mol acidum nicotinicum, heating fractionation, dimension
103-105 DEG C of the temperature of fractionation capital is held, is dropped at a temperature of capital is fractionated, shows that reaction has been completed, mixed liquor is cooled to
10-20 DEG C, filter, and washed three times with ethanol, with ethyl alcohol recrystallization, obtain ligand L, the % of yield 65.
Step（1）Described in g-C3N4@MOF nanocrystals, it is the graphite phase carbon nitride load MOF that 2D folds are layering
The binary composite that nanocrystal is formed；The chemical formula of MOF nanocrystals is [(AgL) ClO4] n, a construction unit is by 1
Individual Ag (I) cationic species, 1 ligand L, 1 ClO4(I) anion forms；MOF nanocrystals, particle diameter 70-90
nm。
Step（2）Described in g-C3N4@MOF@Ag nano composite materials, are g-C3N4@MOF nanocrystal loaded Ags are received
The trielement composite material that rice corpuscles is formed；The average grain diameter of Ag nano-particles is 4 nm.
2. preparation method as described above prepare based on MOF ternary nano composite material as electrochemical sensing detection
The application of penicillamine enantiomer, step are as follows：
（1）Prepare g-C3N4@MOF@Ag nano composite material working sensor electrodes
Polish in alumina powder, the basal electrode glassy carbon electrode surface of water and ethanol cleaning, the uL g- of drop coating 6
C3N4@MOF@Ag Nanocomposite solutions, room temperature are dried, that is, g-C has been made3N4@MOF@Ag nano composite materials are built
Working sensor electrode；
The g-C3N4@MOF@Ag Nanocomposite solutions, are by 3 mg g-C3N4@MOF@Ag nano composite materials
Ultrasonic 10-15min is blended and is made with 250 uL isopropanols, 720 uL water, 30 uL Nafion；
（2）Prepare g-C3N4@MOF@Ag nano composite material electrochemical sensors
By step（1）Obtained working electrode, reference electrode and electrode is connected on electrochemical workstation, g- has been made
C3N4@MOF@Ag nano composite material electrochemical sensors；
The reference electrode is saturated calomel electrode, is platinum electrode to electrode；
（3）Detect D- (-)-penicillamine and L- (+)-penicillamine enantiomer
With pH 7,0.1 mol L-1Phosphate buffer solution PBS, using step（2）Obtained g-C3N4@ MOF@
Ag nano composite material electrochemistry chiral sensors, using D- (-)-green grass or young crops of differential pulse voltammetry, respectively measure various concentrations
The current value of mould amine and L- (+)-penicillamine standard liquid, draw g-C3N4The D- of@MOF@Ag nano composite material sensors
(-)-penicillamine and L- (+)-penicillamine enantiomer working curve；Testing sample D- (-)-penicillamine and L- (+)-penicillamine is molten
Liquid replaces D- (-)-penicillamine or L- (+)-penicillamine standard liquid respectively, carries out D- (-)-penicillamine and L- (+)-green grass or young crops in sample
The detection of mould amine content.
The chiral sensor is 0.01- to the detection range of D- (-)-penicillamine and L- (+)-penicillamine mapping liquid solution
1.0×10-11 g/mL。
The beneficial technique effect of the present invention is as follows：
（1）Method is easy
G-C of the present invention3N4The preparation method of@MOF nanocrystals, it is that one-step method is blended by raw material to be made, g-C3N4@MOF receive
Meter Jing Ti generation is to be based on the g-C caused by material concentration height in solvent for use3N4@MOF nanocrystals solubility reduces
It is caused；g-C3N4The preparation of@MOF nanocrystals, process is simple, easily operated, cost is low, less energy consumption, is easy to industrialize；And
Prepared by MOF preparation generally use solvent-thermal method heating, the even 150 DEG C of heating of some MOF crystal are made for 3 days, manufacturing cycle
It is long, high energy consumption, and usually cannot get nanocrystal.The preparation method solvent load of the present invention significantly reduces, and not only reduces into
This, has been significantly reduced caused by spent solvent and has polluted, added economic and social benefit.
G-C of the present invention3N4The introducing of Ag nano-particles, is by adding appropriate Br in@MOF@Ag nano composite materials
(I) anion captures [(AgL) ClO4] n planes of crystal Ag (I) cation, be formed in situ AgBr, it is in situ that AgBr is shown in that light decomposes
Ag nano-particles are generated, because the confinement of MOF crystal acts on so that Ag nano-particle average grain diameters are only 4 nm.
（2）There is Sensitive Detection D- (-)-penicillamine and L- (+)-penicillamine enantiomer
G-C provided by the invention3N4@MOF@Ag nano composite material electrochemistry chiral sensors, are by g-C3N4@ MOF@
The simply modification of Ag nano composite materials is made in glassy carbon electrode surface, and preparation method is simple, easy to operate.Due to g-C3N4@ MOF@
Ag nano composite materials are by g-C3N4, MOF nanocrystals and nanometer Ag composition, expose more and different avtive spots, play
Synergy so that the chiral sensor prepared based on the composite, detection D- (-)-penicillamine and L- (+)-penicillamine
The content of chiral enantiomer, there is wide quick response, detection range, high sensitivity, simple to operate.
Embodiment
With reference to embodiment, the invention will be further described, but protection scope of the present invention is not only limited to implement
Example, the change that professionals in the field is made to technical solution of the present invention, all should belong in protection scope of the present invention.
A kind of preparation method of the ternary nano composite material based on MOF of embodiment 1.
（1）Prepare g-C3N4@MOF nanocrystals
By 0.34 g AgClO4With 0.068 g graphite phase carbon nitrides g-C3N41 mL water is dissolved in, obtains g-C3N4@Ag (I) are water-soluble
Liquid；0.45 g ligand Ls are dissolved in 1 mL methanol, obtain the methanol solution of ligand L；By g-C3N4@Ag (I) aqueous solution and ligand L
Methanol solution shaking blending, stand 2 h, centrifuge and simultaneously wash 3 times with methanol, obtained g-C3N4@MOF nanocrystals；
（2）Prepare g-C3N4@MOF@Ag nano composite materials
By obtained g-C3N4@MOF nanocrystals, add 4 mL, the KBr ethanol solutions that mass fraction is 5 %, mix, room
Temperature stands 24 h, centrifuges and is washed 3 times with ethanol, 70 DEG C of dryings, and g-C is made3N4@MOF@Ag nano composite materials, i.e.,
Ternary nano composite material based on MOF.
A kind of preparation method of the ternary nano composite material based on MOF of embodiment 2
（1）Prepare g-C3N4@MOF nanocrystals
By 0.45 g AgClO4With 0.090 g graphite phase carbon nitrides g-C3N41.5 mL water are dissolved in, obtain g-C3N4@Ag (I) water
Solution；0.45 g ligand Ls are dissolved in 2 mL methanol, obtain the methanol solution of ligand L；By g-C3N4@Ag (I) aqueous solution is with matching somebody with somebody
Body L methanol solution shaking blending, stands 3 h, centrifuges and washed 3 times with methanol, g-C is made3N4@MOF nanocrystals；
（2）Prepare g-C3N4@MOF@Ag nano composite materials
By obtained g-C3N4@MOF nanocrystals, add 6 mL, the KBr ethanol solutions that mass fraction is 5 %, mix, room
Temperature stands 24 h, centrifuges and is washed 3 times with ethanol, 70 DEG C of dryings, and g-C is made3N4@MOF@Ag nano composite materials, i.e.,
Ternary nano composite material based on MOF.
Embodiment 3
1. a kind of preparation method of the ternary nano composite material based on MOF, step are as follows：
（1）Prepare g-C3N4@MOF nanocrystals
By 0.40 g AgClO4With 0.075 g graphite phase carbon nitrides g-C3N41.2 mL water are dissolved in, obtain g-C3N4@Ag (I) water
Solution；0.45 g ligand Ls are dissolved in 1.5 mL methanol, obtain the methanol solution of ligand L；By g-C3N4@Ag (I) aqueous solution with
The methanol solution shaking blending of ligand L, stands 2.5 h, centrifuges and washed 3 times with methanol, g-C is made3N4@MOF nanometers
Crystal；
（2）Prepare g-C3N4@MOF@Ag nano composite materials
By obtained g-C3N4@MOF nanocrystals, add 5 mL, the KBr ethanol solutions that mass fraction is 5 %, mix, room
Temperature stands 24 h, centrifuges and is washed 3 times with ethanol, 70 DEG C of dryings, and g-C is made3N4@MOF@Ag nano composite materials, i.e.,
Ternary nano composite material based on MOF.
Graphite phase carbon nitride g-C described in the embodiment 1-3 of embodiment 43N4Preparation method
3g dicyandiamides are put into crucible, are compacted, air atmosphere in tube furnace is placed in and calcines, heating rate is 2.3 DEG C/min, is risen to
500 DEG C, insulation 4h, natural cooling, are made graphite phase carbon nitride g-C3N4。
The preparation method of ligand L described in the embodiment 1-3 of embodiment 5
Under stirring condition, 0.10 mol 1,2- ethylenediamines are mixed with 0.20 mol acidum nicotinicum, heating fractionation, dimension
103-105 DEG C of the temperature of fractionation capital is held, is dropped at a temperature of capital is fractionated, shows that reaction has been completed, mixed liquor is cooled to 10
DEG C, filter, and washed three times with ethanol, obtain ligand L, yield 65% with ethyl alcohol recrystallization；Ligand L, structural formula are as follows：
Embodiment 6
G-C described in embodiment 1-33N4@MOF nanocrystals, it is that the graphite phase carbon nitride load MOF that 2D folds are layering receives
The binary composite that meter Jing Ti is formed；The chemical formula of MOF nanocrystals is [(AgL) ClO4] n, a construction unit is by 1
Ag (I) cationic species, 1 ligand L, 1 ClO4(I) anion forms；MOF nanocrystals, particle diameter are 70-90 nm.
G-C described in embodiment 1-33N4@MOF@Ag nano composite materials, are g-C3N4@MOF nanocrystal loaded Ags are received
The trielement composite material that rice corpuscles is formed；The average grain diameter of Ag nano-particles is 4 nm.
The answering as electrochemical sensing detection penicillamine enantiomer based on MOF ternary nano composite material of embodiment 7
With
（1）Prepare g-C3N4@MOF@Ag nano composite material working sensor electrodes
Polish in alumina powder, the basal electrode glassy carbon electrode surface of water and ethanol cleaning, the uL embodiments of drop coating 6
1 g-C prepared3N4@MOF@Ag Nanocomposite solutions, room temperature are dried, that is, g-C has been made3N4@MOF@Ag nanometers are answered
The working sensor electrode of condensation material structure；
The g-C3N4@MOF@Ag Nanocomposite solutions, are by 3 mg g-C3N4@MOF@Ag nano composite materials
Ultrasonic 10-15min is blended and is made with 250 uL isopropanols, 720 uL water, 30 uL Nafion；
（2）Prepare g-C3N4@MOF@Ag nano composite material electrochemical sensors
By step（1）Obtained working electrode, reference electrode and electrode is connected on electrochemical workstation, g- has been made
C3N4@MOF@Ag nano composite material electrochemical sensors；
The reference electrode is saturated calomel electrode, is platinum electrode to electrode；
（3）Detect D- (-)-penicillamine and L- (+)-penicillamine enantiomer
With pH 7,0.1 mol L-1Phosphate buffer solution PBS, using step（2）Obtained g-C3N4@ MOF@
Ag nano composite material electrochemistry chiral sensors, using D- (-)-green grass or young crops of differential pulse voltammetry, respectively measure various concentrations
The current value of mould amine and L- (+)-penicillamine standard liquid, draw g-C3N4The D- of@MOF@Ag nano composite material sensors
(-)-penicillamine and L- (+)-penicillamine enantiomer working curve；Testing sample D- (-)-penicillamine and L- (+)-penicillamine is molten
Liquid replaces D- (-)-penicillamine or L- (+)-penicillamine standard liquid respectively, carries out D- (-)-penicillamine and L- (+)-green grass or young crops in sample
The detection of mould amine content.
Embodiment 8
Method embodiment 7, only will more g-C wherein made from embodiment 13N4@MOF@Ag nano composite materials replace with reality
Apply g-C made from example 23N4@MOF@Ag nano composite materials.
Embodiment 9
Method embodiment 7, only will g-C wherein made from embodiment 13N4@MOF@Ag nano composite materials replace with implementation
G-C made from example 33N4@MOF@Ag nano composite materials.
Embodiment 10
Detection range of the chiral sensor made from embodiment 7-9 to D- (-)-penicillamine and L- (+)-penicillamine mapping liquid solution
For 0.01-1.0 × 10-11 g/mL。
Claims (7)
1. a kind of preparation method of the ternary nano composite material based on MOF, it is characterised in that step is as follows：
（1）Prepare g-C3N4@MOF nanocrystals
By 0.34-0.45 g AgClO4With 0.068-0.090 g graphite phase carbon nitrides g-C3N41-1.5 mL water is dissolved in, obtains g-
C3N4@Ag (I) aqueous solution；0.45 g ligand Ls are dissolved in 1-2 mL methanol, obtain the methanol solution of ligand L；By g-C3N4@Ag
(I) aqueous solution and the shaking of the methanol solution of ligand L are blended, and stand 2-3 h, centrifuge and washed 3 times with methanol, g- is made
C3N4@MOF nanocrystals；
（2）Prepare g-C3N4@MOF@Ag nano composite materials
By obtained g-C3N4@MOF nanocrystals, add 4-6 mL, the KBr ethanol solutions that mass fraction is 5 %, mix, room
Temperature stands 24 h, centrifuges and is washed 3 times with ethanol, 70 DEG C of dryings, and g-C is made3N4@MOF@Ag nano composite materials, i.e.,
Ternary nano composite material based on MOF.
2. the preparation method of the ternary nano composite material based on MOF as claimed in claim 1, it is characterised in that the stone
Black phase carbon nitride g-C3N4, preparation method is as follows：
3g dicyandiamides are put into crucible, are compacted, air atmosphere in tube furnace is placed in and calcines, heating rate is 2.3 DEG C/min, is risen to
500 DEG C, insulation 4h, natural cooling, are made graphite phase carbon nitride g-C3N4。
3. the preparation method of the ternary nano composite material based on MOF as claimed in claim 1, it is characterised in that described to match somebody with somebody
Body L, structural formula are as follows：
The preparation process of ligand L is as follows：
Under stirring condition, 0.10 mol 1,2- ethylenediamines are mixed with 0.20 mol acidum nicotinicum, heating fractionation, dimension
103-105 DEG C of the temperature of fractionation capital is held, is dropped at a temperature of capital is fractionated, shows that reaction has been completed, mixed liquor is cooled to
10-20 DEG C, filter, and washed three times with ethanol, with ethyl alcohol recrystallization, obtain ligand L, the % of yield 65.
4. the preparation method of the ternary nano composite material based on MOF as claimed in claim 1, it is characterised in that the g-
C3N4@MOF nanocrystals, it is that the binary for the graphite phase carbon nitride load MOF nanocrystal compositions that 2D folds are layering is compound
Material；The chemical formula of MOF nanocrystals is [(AgL) ClO4] n, a construction unit by 1 Ag (I) cationic species, 1
Ligand L, 1 ClO4(I) anion forms；MOF nanocrystals, particle diameter are 70-90 nm.
5. the preparation method of the ternary nano composite material based on MOF as claimed in claim 1, it is characterised in that the g-
C3N4@MOF@Ag nano composite materials, are g-C3N4The tri compound material that@MOF nanocrystal loaded Ags nano-particle is formed
Material；The average grain diameter of Ag nano-particles is 4 nm.
6. preparation method as claimed in claim 1 prepare based on MOF ternary nano composite material as electrochemical sensing inspection
Survey the application of penicillamine enantiomer.
7. the application of electrochemical sensing detection penicillamine enantiomer as claimed in claim 5, it is characterised in that step is as follows：
（1）Prepare g-C3N4@MOF@Ag nano composite material working sensor electrodes
Polish in alumina powder, the basal electrode glassy carbon electrode surface of water and ethanol cleaning, the uL g-C of drop coating 63N4@
MOF@Ag Nanocomposite solutions, room temperature are dried, that is, g-C has been made3N4The sensing of@MOF@Ag nano composite materials structure
Device working electrode；
The g-C3N4@MOF@Ag Nanocomposite solutions, are by 3 mg g-C3N4@MOF@Ag nano composite materials
Ultrasonic 10-15min is blended and is made with 250 uL isopropanols, 720 uL water, 30 uL Nafion；
（2）Prepare g-C3N4@MOF@Ag nano composite material electrochemical sensors
By step（1）Obtained working electrode, reference electrode and electrode is connected on electrochemical workstation, g-C has been made3N4@
MOF@Ag nano composite material electrochemical sensors；
The reference electrode is saturated calomel electrode, is platinum electrode to electrode；
（3）Detect D- (-)-penicillamine and L- (+)-penicillamine enantiomer
With pH 7,0.1 mol L-1Phosphate buffer solution PBS, using step（2）Obtained g-C3N4@ MOF@ Ag
Nano composite material electrochemistry chiral sensor, using D- (-)-mould of differential pulse voltammetry, respectively measure various concentrations
The current value of amine and L- (+)-penicillamine standard liquid, draw g-C3N4The D- (-) of@MOF@Ag nano composite material sensors-
Penicillamine and L- (+)-penicillamine enantiomer working curve；By testing sample D- (-)-penicillamine and L- (+)-mould amine aqueous solution point
Not instead of D- (-)-penicillamine or L- (+)-penicillamine standard liquid, D- (-)-penicillamine and L- (+)-penicillamine in sample are carried out
The detection of content.
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| CN108435253A (en) * | 2018-01-29 | 2018-08-24 | 江苏大学 | A kind of C3N4Carry difunctional MOFs based composite catalysts of soda acid and its preparation method and application |
| CN108745404A (en) * | 2018-06-14 | 2018-11-06 | 苏州大学 | Carbon nitride films composite material and preparation method and the application in exhaust-gas treatment based on black phosphorus/metal organic frame modification |
| CN109261134A (en) * | 2018-11-21 | 2019-01-25 | 哈尔滨工程大学 | Physics and chemical cooperated fouling resistance type extraction of uranium from seawater adsorbent and preparation method thereof |
| CN109261134B (en) * | 2018-11-21 | 2021-05-28 | 哈尔滨工程大学 | Physical and chemical synergistic anti-pollution type uranium extraction from seawater adsorbent and preparation method thereof |
| CN112570027A (en) * | 2019-09-30 | 2021-03-30 | 吉林师范大学 | Preparation method, material structure and application of silver/metal organic framework/carbon nitride-based composite photocatalyst |
| CN110702840A (en) * | 2019-10-14 | 2020-01-17 | 刘芳 | Analysis device based on energy utilization rate of carbonized urban domestic sewage biomass |
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| CN111551596A (en) * | 2020-05-20 | 2020-08-18 | 晋中学院 | Preparation method of photoelectric chemical sensor for efficiently and sensitively detecting kanamycin |
| CN111551596B (en) * | 2020-05-20 | 2022-06-03 | 晋中学院 | Preparation method of photoelectric chemical sensor for efficiently and sensitively detecting kanamycin |
| CN112834478A (en) * | 2020-12-16 | 2021-05-25 | 江苏师范大学 | Based on AgNPs/MOFs/g-C3N4Composite film and preparation method and application thereof |
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