CN107582440B - A kind of blueing light microemulsion preconcentrate and preparation method thereof - Google Patents
A kind of blueing light microemulsion preconcentrate and preparation method thereof Download PDFInfo
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- CN107582440B CN107582440B CN201711064379.2A CN201711064379A CN107582440B CN 107582440 B CN107582440 B CN 107582440B CN 201711064379 A CN201711064379 A CN 201711064379A CN 107582440 B CN107582440 B CN 107582440B
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Abstract
The invention discloses a kind of blueing light microemulsion preconcentrates, which is characterized in that by weight, including following component: 13-16 parts of nonionic emulsifier；13-18 parts of oil components；5-15 parts of polyalcohol.The present invention is by selecting nonionic emulsifier, oil components and polyalcohol to compound, and select the nonionic emulsifier of particular types and specified weight ratio, and select the oil components of particular types and specified weight ratio, it is prepared more excellent with skin sense, mildness is more preferable, and can obtain the microemulsion preconcentrate that appearance is consistent, partial size is small and stability is good between batch.
Description
Technical field
The present invention relates to cosmetic field, in particular to a kind of blueing light microemulsion preconcentrate and preparation method thereof.
Background technique
So-called microemulsion is usually said by oil components, water composition and surface-active there are point of broad sense and narrow sense
The thermodynamically stable isotropic liquid of agent and auxiliary agent composition belongs to the microemulsion of narrow sense；And the microemulsion of broad sense refer to due to
The small appearance with transparent or semitransparent blueing light of partial size, thermodynamically unstable microemulsion.Signified micro emulsion in the present invention
Liquid refers both to sensu lato microemulsion.
The method for usually preparing microemulsion has high pressure homogenization method, ultrasonic emulsification, D phase emulsion process, PIT emulsion process, coagulates
Poly- method etc..And studies have found that, microemulsion, which is prepared, using ionic surface active agent needs higher surfactant and dispersed
The relative ratios of phase；And some nonionic surfactants prepare microemulsion, need the amount of surfactant just much lower, are not required to
Adding cosurfactant can be made.But from the point of view of the narrow temperature being likely to form from microemulsion, temperature is to system
Appearance and stability suffer from particularly important influence.
Up to the present, microemulsion preconcentrate is prepared by using agglutination, and by using nonionic surfactant
The microemulsion preconcentrate of preparation is because dosage of surfactant is few, and skin sense is more excellent, and mildness is more preferable, and can obtain appearance one between batch
It causes, the microemulsion preconcentrate that partial size is small and stability is good is not shown in relevant report also.
Summary of the invention
The present invention is directed to provide it is a kind of have skin sense more excellent, mildness is more preferable, and can obtain that appearance between batch is consistent, grain
Diameter is small and the good microemulsion preconcentrate of stability.
Blueing light microemulsion preconcentrate of the present invention, by weight, including following component:
13-16 parts of nonionic emulsifier；
13-18 parts of oil components；
5-15 parts of polyalcohol.
Wherein, the nonionic emulsifier includes hydrophilic PEG-60 rilanit special, hydrophilic stereth -20
And lipophilic -2 diisopstearate of polyglycereol, and the weight ratio between three is 8-10:2-3.5:1.5-4.Pass through control
Weight ratio between three processed can get the microemulsion of stable homogeneous, even if storing 4 weeks under the conditions of 50 DEG C and -15 DEG C not
It can be there is a phenomenon where layering or muddy；When the weight ratio between three be below or above the range, stable homogeneous can not be formed
Microemulsion, it may appear that the phenomenon that white opacity and surface oil slick.
Wherein, the oil components include glycerol three (thylhexoic acid) ester, saualane and vitamin E, and between three
Weight percent be 8-10:3.2-4:3.2-4.By the weight ratio between control three, the micro emulsion of stable homogeneous can get
Liquid, even if storage 4w will not be there is a phenomenon where layering or muddy under the conditions of 50 degree and -15 degree；When the weight ratio between three
Lower than the range, if glycerol three (thylhexoic acid) ester dosage can be temporarily forming uniform lotion when low, but particle is not tiny enough, does not have
Blue light occurs, and stability is also poor, may be too low due to their polarity when increasing saualane or vitamin E dosage, leads to nothing
The microemulsion of method formation stable homogeneous, it may appear that the phenomenon that white opacity and surface oil slick；When the weight ratio between three is higher than
The range, if glycerol three (thylhexoic acid) ester dosage is too high, oil mutually can not be emulsified all, it may appear that white opacity and surface
The phenomenon that oil slick, can be temporarily forming white blueing light microemulsion when reducing saualane or when vitamin E dosage, but stability compared with
Difference.
Wherein, the polyalcohol is selected from glycerol, propylene glycol, butanediol, 1,2- pentanediol, 1,2- hexylene glycol, ethyl alcohol, poly- second
One or more of glycol -8, polyethylene glycol -32, diglycerol, Natrulon H-10, glycerin polyether -26.
Above-mentioned blueing light microemulsion preconcentrate can also include by weight 0-1 portions of preservatives and 5-20 parts of water.
The preservative is selected from one or more of Sensiva SC50, decoyl hydroximic acid, glycerol caprylate.
In addition, including the following steps: the invention also discloses the preparation method of above-mentioned blueing light microemulsion preconcentrate
1) oil components and nonionic emulsifier are mixed, is heated to 60-80 DEG C and is completely dissolved, A phase is made；
2) 5-20 parts of water is heated to 80-90 DEG C, B phase is made；
3) quickly A is added in B phase under stirring, is continuously heating to 90 DEG C or more, C phase is made；
4) C phase is poured into the remaining water phase quickly stirred, is cooled down while stirring, sequentially added polyalcohol, preservative, stir
It mixes and uniformly obtains blueing light microemulsion preconcentrate.
Compared with prior art, the invention has the following beneficial effects:
The present invention by selecting nonionic emulsifier, oil components and polyalcohol to compound, and select particular types and
The nonionic emulsifier of specified weight ratio, and the oil components of particular types and specified weight ratio are selected, being prepared has
Skin sense is more excellent, and mildness is more preferable, and can obtain the microemulsion preconcentrate that appearance is consistent, partial size is small and stability is good between batch.
Specific embodiment
Further illustrate that the present invention, following embodiment are the preferable embodiment party of the present invention below by specific embodiment
Formula, but embodiments of the present invention are not limited by following embodiments.
The embodiment of the present invention and comparative example use the following raw material, but are not limited only to these raw materials:
Nonionic emulsifier: PEG-60 rilanit special, it is commercially available；
Stereth -20, it is commercially available；
- 2 diisopstearate of polyglycereol, it is commercially available；
Oil components: glycerol three (thylhexoic acid) ester, it is commercially available；
Saualane, it is commercially available；
Vitamin E, it is commercially available；
Polyalcohol: glycerol, it is commercially available；
1,3-BDO, it is commercially available；
Preservative: Sensiva SC50, it is commercially available；
Decoyl hydroximic acid, it is commercially available；
Glycerol caprylate, it is commercially available.
The test method and evaluation criterion of each performance indicator:
Skin sense and mildness evaluation method: the microemulsion preconcentrate of embodiment and comparative example is made into 10% respectively, 20% concentration
Aqueous solution as smoothing toner, organize 15 people or so volunteer's Evaluation product, respectively for the index as described in Table 1 of product and
General impression makes evaluation, by 1-5 points of evaluations and assembly average.
Skin sense general impression and mildness evaluation method: the microemulsion preconcentrate of embodiment and comparative example is made into 10% concentration
Aqueous solution as smoothing toner, organize 15 people or so volunteer's Evaluation product, done respectively for the index as described in Table 1 of product
It evaluates out, by 1-5 points of evaluations, the skin sense general impression average value=corresponding weight of each index scoring */weight adduction, mildness is pressed
1-5 points of evaluations, assembly average；Evaluation criterion is as shown in table 1, and evaluation result is as shown in table 2.
Table 1
Ocular estimate method: range estimation, the same embodiment and comparative example repeatedly draw a design, and to compare appearance consistent；
Particle size measuring method: it is measured using Malvern laser diffractometry Particle Size Analyzer；
Stability test and evaluation method: by the sample of embodiment and comparative example respectively in 25 DEG C, -15 DEG C, 50 DEG C of storages 4
Week, observation product appearance have it is unchanged, evaluation criterion press A, B, C three grades, A=do not find differences compared with 25 DEG C of samples,
The slight difference of B=have compared with 25 DEG C of samples, C=have compared with 25 DEG C of samples are significantly different.
Embodiment 1-5 and comparative example 1-12: the preparation of blueing light microemulsion preconcentrate
Oil components and nonionic emulsifier are mixed according to the proportion of table 2,60-80 DEG C is heated to and is completely dissolved, A is made
Phase；5-20 parts of water is heated to 80-90 DEG C, B phase is made；A is added in B phase under quick stirring, is continuously heating to
90 DEG C or more, C phase is made；C phase is poured into the remaining water phase quickly stirred, is cooled down while stirring, polyalcohol is sequentially added, prevents
Rotten agent stirs evenly up to blueing light microemulsion preconcentrate.The skin sense of gained blueing light microemulsion preconcentrate and mildness, appearance, grain
The performance indicators such as diameter size and stability are as shown in table 2.
The each group distribution ratio and each testing performance index result of table 2 embodiment 1-5 and comparative example 1-12
Continued 2
。
Claims (4)
1. a kind of blueing light microemulsion preconcentrate, which is characterized in that 100 parts by weight meters, including following component:
13-16 parts of nonionic emulsifier；
13-18 parts of oil components；
5-15 parts of polyalcohol；
The nonionic emulsifier includes hydrophilic PEG-60 rilanit special, hydrophilic stereth -20 and lipophilicity
- 2 diisopstearate of polyglycereol, and the weight ratio between three be 8-10:2-3.5:1.5-4；
The oil components include glycerol three (thylhexoic acid) ester, saualane and vitamin E, and the weight ratio between three is
8-10:3.2-4:3.2-4.
2. blueing light microemulsion preconcentrate according to claim 1, which is characterized in that the polyalcohol is selected from glycerol, the third two
Alcohol, butanediol, 1,2- pentanediol, 1,2- hexylene glycol, polyethylene glycol-8, polyethylene glycol -32, diglycerol, Natrulon H-10, glycerol
One or more of polyethers -26.
3. blueing light microemulsion preconcentrate according to claim 1, which is characterized in that further include 0-1 parts anti-by weight
Rotten agent and excess water.
4. a kind of preparation method of blueing light microemulsion preconcentrate as described in any one of claims 1-3, which is characterized in that including
Following steps:
1) oil components and nonionic emulsifier are mixed, is heated to 60-80 DEG C and is completely dissolved, A phase is made；
2) 5-20 parts of water is heated to 80-90 DEG C, B phase is made；
3) quickly A is added in B phase under stirring, is continuously heating to 90 DEG C or more, C phase is made；
4) C phase is poured into the remaining water phase quickly stirred, is cooled down while stirring, sequentially add polyalcohol, preservative, stirring is equal
It is even to obtain blueing light microemulsion preconcentrate.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101966135A (en) * | 2010-09-30 | 2011-02-09 | 江苏隆力奇生物科技股份有限公司 | Toning lotion and preparation method thereof |
| CN102281858A (en) * | 2009-01-14 | 2011-12-14 | 株式会社资生堂 | Process for producing O/W microemulsion preparation for external application |
| CN104379118A (en) * | 2011-12-23 | 2015-02-25 | 奇华顿股份有限公司 | Composition |
| CN106420372A (en) * | 2016-11-18 | 2017-02-22 | 广东芭薇生物科技股份有限公司 | Semitransparent toning lotion and preparation method thereof |
-
2017
- 2017-11-02 CN CN201711064379.2A patent/CN107582440B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102281858A (en) * | 2009-01-14 | 2011-12-14 | 株式会社资生堂 | Process for producing O/W microemulsion preparation for external application |
| CN101966135A (en) * | 2010-09-30 | 2011-02-09 | 江苏隆力奇生物科技股份有限公司 | Toning lotion and preparation method thereof |
| CN104379118A (en) * | 2011-12-23 | 2015-02-25 | 奇华顿股份有限公司 | Composition |
| CN106420372A (en) * | 2016-11-18 | 2017-02-22 | 广东芭薇生物科技股份有限公司 | Semitransparent toning lotion and preparation method thereof |
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