CN107567340A - Track indexing syringe - Google Patents
Track indexing syringe Download PDFInfo
- Publication number
- CN107567340A CN107567340A CN201680026701.XA CN201680026701A CN107567340A CN 107567340 A CN107567340 A CN 107567340A CN 201680026701 A CN201680026701 A CN 201680026701A CN 107567340 A CN107567340 A CN 107567340A
- Authority
- CN
- China
- Prior art keywords
- engagement member
- syringe
- plunger rod
- cylinder
- main body
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/31573—Accuracy improving means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/31573—Accuracy improving means
- A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
- A61M5/31595—Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
Abstract
The present invention relates to a kind of syringe (100), the syringe includes:Cylinder (1);The plunger (2) being movably arranged in the cylinder (1) and the plunger rod (3) for driving the plunger (2);And engagement member (4), the engagement member, which is arranged at the cylinder (1), to be sentenced and is engaged with the grooved surfaces (5) on the plunger rod (3).When the plunger rod (3) is moved to drive plunger (2) in the cylinder (1) relative to the cylinder (1), the feedback to user will be produced.The cylinder (1) and the engagement member (4) are arranged so that relative to each other, when the plunger rod (3) is mobile relative to the cylinder (1), the engagement member (4) only moves because the grooved surfaces (5) with the plunger rod (3) engage along the direction for the longitudinal direction for being generally orthogonal to the plunger rod (3).
Description
Technical field
The present invention relates to syringe and relate more specifically to provide the note of feedback for user in use
Emitter.
Background technology
When the user of medical syringe gives material, especially in some therapy fields, generally syringe is carried
Cumulative volume be distributed on some region.Some examples of such therapy field be dermatology, plastic operation, cosmetic surgery,
And dentistry.For example, this distribution just side and is roughly parallel under the surface of the skin by the way that the pin of syringe is inserted into
Skin surface and then while pin is extracted give material to complete.Another way is several in finite region
Material is given at individual anatomical location, i.e., a part for cumulative volume is given in each opening position.It is used to be distributed at these and other
In the method for material, if syringe is equipped with for aiding in user to know to give thing in each position or per time unit
Certain how most administration auxiliary of matter cumulative volume, then be favourable.Therefore, syringe cylinder is equipped with magnitude scale, and
User observes the position of plunger along the scale.However, scale is difficult to see that and there may come a time when by paster or similar
Thing is partially or even wholly covered, and syringe is sometimes held with the angle for causing scale to be hidden.On syringe cylinder
Another practical problem of the magnitude scale of offer is, to provide very small amount of material sometimes, and this correspondingly needs plunger
Small movement is carried out in cylinder, and the movement is likely difficult to be readily detectable by a user.In addition, so using the main of magnitude scale
Problem is that user must observe it in injection process, it means that must usually look at magnitude scale as user and
It is not that when being absorbed in the event progress at area for treatment, dispersion attention can be caused.It is used for providing the machine being accurately administered
Tool or electron injector, but they are more more expensive than syringe and heavier, and many users are had a preference for hold conventional note
The mode of emitter holds injection device.Taken out in addition, most of injectors do not allow user to enter the hand-manipulating of needle before medicament is injected
Inhale.The shortcomings that this is serious, because it does not allow user to recognize to have been completed injection in the blood vessel.Also, this is prevented
Before injection using the material for needing to be drawn into from the holder comprising material in syringe cylinder.
The trial that administration auxiliary is provided to syringe is disclosed in WO 2008/057976, wherein in finger grips
On provide engagement member and it is engaged with the structure of plunger rod.
The content of the invention
It is advantageous to provide a kind of syringe with user close friend's device, user close friend's device informs user
Injection rate or charge velocity simultaneously provide the feedback on it and also have simple construction.
At least some in these worries in order to preferably solve, in the first aspect of the present invention, presenting one kind includes
The syringe of cylinder and the plunger being movably arranged in this tin.The syringe further comprises plunger rod, the plunger rod purport
The plunger is driven in the direction along the longitudinal direction parallel to the plunger rod to release or inhaled material.In addition, at the cylinder
Engagement member is scheduled, to be engaged with the grooved surfaces set on the plunger rod so that when the plunger is relative to this
When cylinder movement is to drive the plunger feedback is provided to user.The cylinder and the engagement member be arranged so that relative to each other,
When the plunger rod relative to the cylinder movement to drive the plunger when, the engagement member is due to the table with groove with the plunger rod
Face engages and interacted and only moved along the direction for the longitudinal direction for being generally orthogonal to the plunger rod.This construction will
Improved administration accuracy is provided.On the solution presented in WO-2008/057976, engagement member positioned at finger by grabbing
Flat element composition on grip top, for example, see Fig. 3 in the prior art document and 4.It is intended to give for example in user
In the case of botulin toxin, the major defect that the prior art solution has is had been acknowledged.Typically, clostridium botulinum
Toxin must be drawn into from holder in the cylinder of the syringe of sky before injection.When this passes through in such as WO-2008/057976
When described syringe is to carry out, at the end of operation is sucked, flat engagement member will be there is a high likelihood that will be located at its quilt
Bend slightly upward and be shelved on the position on the ridge of the grooved surfaces of plunger rod.The engagement member of the prior art is therefore
Biased along the direction of mistake.Generally, the one click from the engagement member represent material in cylinder, with plunger rod band groove
Some corresponding dosage of the distance between two adjacent ridges on surface.However, the engagement structure due to WO-2008/057976
The original position of part is in the position that it is bent slightly upward, therefore plunger rod must produce at first point in the engagement member
Hit before sound that advance must be set more much farther away than initial.In this case, the engagement member must be first slightly upward curved from it
Folding is positioned against it as horizontal position movement and hereafter slightly bent downwards towards it before the first click sound is produced
Position movement.Certainly, continue to move to that phase interaction between the engagement member and the grooved surfaces of the plunger rod will be caused
With the click sound for producing repetition with predetermined dose.However, test proves that the first dosage of such prior art configuration can
It can be actual set up to three times, and such excessive dosage is destructive to patient in some cases, such as make
Into unexpected muscular paralysis.It should also be noted that these click sound continued are the engagement structures in prior art solution
Part is located at caused by the case of the position more or less bent downwards all the time.This means in injection process, when this connects
When conjunction component crosses the ridge of the grooved surfaces of the plunger rod moved and hits adjacent ridge and therefore produce click sound,
It is likely that horizontal level is never presented in it.Therefore, may be discharged according to the syringe of the prior art solution excessive
Another situation of dosage is:When for example when click function is switched off during suction or inhaled material, or for some
When reason is switched off over the course for the treatment of.If hereafter recovering click function again, engagement member will be introduced into groove
The neutral position of the longitudinal direction perpendicular to plunger rod is reached in surface and plunger rod therefore will be needed to produce the first click
Advancing before sound must be set more farther than initial.This is equally applicable to use with such as the engagement structure described in the prior art
The situation of the pre-filled syringe of part.In this case, engagement member will be positioned in longitudinal direction perpendicular to plunger rod
Position and will also require the plunger rod before the first click sound is produced and advance must be set more farther than initial.Pass through this
The solution of invention, wherein engagement member are arranged to only along the direction of the longitudinal direction perpendicular to plunger rod advance, and avoid
This shortcoming.Similar to WO-2008/057976, in the present invention, between two ridges of the grooved surfaces of plunger rod
Distance is corresponding with some dosage and is represented in use with one click.With the prior art solution phase
Than by the syringe according to the present invention, the first time after material is had been drawn into, which is clicked on, represents dosage only once.This is
Because according to the engagement member of the present invention never need to it is any it is initial before come in release the biasing along the opposite way round, such as existing skill
As required for art solution.Because the present invention engagement member will never as prior art solution,
Only initially start with the movement of grooved surfaces towards the even generation click sound of the engagement member of the plunger rod
Advance position.But engagement member of the invention moves back and forth between outer end position and inner end positions all the time, and with the plunger
Bar is mobile or previously to have moved the direction of (for example, after inhaled material) unrelated.Therefore, excessive dosage (prior art solution
Certainly scheme has this risk) it is impossible for the present invention.
According to the embodiment of the syringe, the engagement member is arranged in the cylinder.
According to the embodiment of the syringe, the engagement member is arranged at this tin, is parallel to the vertical of the plunger rod
It is immovable on to the direction in direction.By avoiding any clearance between this tin and the engagement member or the like, improve
Administration accuracy.
According to the embodiment of the syringe, the immovable arrangement of the engagement member at this tin is by close
Coordinate and realize.Tight fit between both parts is that they are arranged into immovable a kind of letter relative to each other
Single reliable way again, because not needing single attachment members or device.
According to the embodiment of the syringe, immovable arrangement of the engagement member at this tin is to pass through snap-lock
And realize.Snap lock is another simple and reliable solution of simple assembling that is easily fabricated and providing syringe.
According to the embodiment of the syringe, the immovable arrangement of the engagement member at this tin is by being pacified
Come what the lid at this tin was realized.Single lid can also be provided the engagement member is fixed on the cylinder.
According to the embodiment of the syringe, the engagement member include main body with circular or semicircular in shape and from this
Main body protrusion is to engage the protrusion element of the grooved surfaces of the plunger rod.At least partly about plunger rod and with to
The circular or semicircle engagement member of interior prominent element (being engaged with the grooved surfaces of the plunger rod) is easily arranged at
In the cylinder that section is typically round, and it is also easy to such engagement member along the side of the longitudinal direction perpendicular to plunger rod
The prestressing force suitable to offer so that the protrusion element abuts the grooved surfaces of the plunger rod all the time.
According to the embodiment of the syringe, the engagement member includes the generally main body of tabular and protruded from the main body
To engage the protrusion element of the grooved surfaces of the plunger rod.The plate-like body with protuberance provides very simple thereon
Manufacture and assembling.
According to the embodiment of the syringe, the edge of the protrusion element along the protrusion element is connected in the main body.This
Individual edge is generally parallel to the longitudinal direction extension of the plunger rod.It is this to arrange that the rigidity of height is provided so that can be with complete
Any deflection that is complete or at least largely avoiding direction of the protrusion element along the longitudinal direction parallel to the plunger rod.
According to the embodiment of the syringe, the protrusion element is that the main body along the edge from the engagement member folds.
By the way that the protrusion element is folded from the main body, powerful and reliable construction is obtained.
According to the embodiment of the syringe, the protrusion element is stamped out from the main body of the engagement member.
According to the embodiment of the syringe, the engagement member includes main body and prominent element with semicircular in shape, its
In the protrusion element be arranged to the extension of the main body and there is the crooked process radius more narrower than the main body so that this is prominent
The end for going out element engages the grooved surfaces of the plunger rod.By the way that the protrusion element with sufficiently narrow radius bend, is somebody's turn to do
Protruding member is by the grooved surfaces for pointing to the plunger rod and is combined.
According to the embodiment of the syringe, the engagement member includes the main body with semicircular in shape and for engaging this
The protrusion element of the grooved surfaces of plunger rod, wherein by along the side for the longitudinal direction for being generally parallel to the plunger rod
Edge folds, and the protrusion element is arranged to the extension of the main body.
According to the embodiment of the syringe, the engagement member be arranged at this tin, be generally configured to annulation every
In room, wherein the plunger rod extends through the inner circle of the annulation, and wherein the engagement member can be passed through in the compartment
Opening engages the grooved surfaces of the plunger rod.
According to the embodiment of the syringe, the two edges attachment of the plate-like body of the engagement member along the plate-like body
To the cylinder.By the way that the tabular component is attached along two possible relative edges, the main body can make the protrusion structure
The grooved surfaces of part towards the plunger rod bias.In addition, this allows the plate-like body to serve as strengthening the syringe
The acoustic membrane of click sound.
According to the embodiment of the syringe, the engagement member, the end that is engaged with the grooved surfaces of the plunger rod
Portion has tapered portion so that the moving direction regardless of the plunger rod, all provides feedback to user.This is important side
Face, because it is usually desirable that also there is click sound in the suction process with material is aspirated.Also, this provides a kind of provide all the time
Show the possibility of the syringe of given original position.For example, when material has been inhaled into the cylinder of syringe and is used
When person discharges the grasping to plunger rod, tapered end can be such that the plunger rod slightly moves, until the tapered end reaches the post
The bottom of the grooved surfaces of stopper rod.This is also required to apply enough for example from the main body of engagement member to protruding member naturally
Preload.This action can be by selecting suitable geometry and surfacing to enter the grooved surfaces of plunger rod
One step mitigates.
The aspect of these and other and advantage of the present invention will be made apparent from embodiment from the description below and will
It is illustrated with reference to it.
Brief description of the drawings
The present invention is more fully described referring now to the following drawings, in the accompanying drawings:
Fig. 1 is the perspective view according to the first embodiment of the syringe of the present invention;
Fig. 2 is the perspective view according to the second embodiment of the syringe of the present invention;
Fig. 3 is the perspective view according to the 3rd embodiment of the syringe of the present invention;
Fig. 4 a and 4b are the section views of a part for Fig. 1 syringe;
Fig. 5 is the perspective view according to the embodiment of the syringe of the present invention;
Embodiment
The embodiment (most of in Fig. 1 schematically to show) of syringe 100 includes cylinder 1, plunger 2 and is arranged
The plunger rod 3 of the plunger 2 is driven during into the use in syringe 100, and equipped with the thumb for actuating plunger bar 3
Plate 14.Plunger rod 3 can be attached on plunger 2 by any suitable means that such as technical staff understands.For example, screw thread connects
It is suitable to connect, because it allows plunger 2 to move in the two directions:That is, it is pushed into and pulls out through cylinder 1, this connects at other
It is not always possible in the case of connecing mode.Syringe 100 further comprises pin 16, and cylinder 1 can be equipped with finger grip
Part 17.Equipped with outer surface 5 with groove, the outer surface has to be provided plunger rod 3 along the length of plunger rod 3 in a manner of alternately
Multiple ridges and trench.This can be by providing a large amount of narrow grooves to realize to plunger rod 3, and these narrow grooves are limited by strait flange
Fixed.It is envisioned that the different shapes of these flanges and being selected as requested.For example, they can hang down from plunger rod
Directly protruded in the longitudinal axis of the plunger rod.Another possibility is to provide such flange with wedge-type shape, the wedge-shaped shape
Shape is symmetrical on extending past the outer sophisticated plane of the flange perpendicular to the longitudinal axis of the plunger rod.It is alternatively possible
Property is asymmetric wedge-type shape.Another possible shape is most preferably disclosed out and can be described as pair in figs 4 a and 4b
Should be in the multiple frustums self stacked.Centre distance allusion quotation between the spacing of these flanges, i.e. two adjacent ribs
Type between 0.1 and 3mm.Typically depend on the size of the cylinder 1 of material to be implanted and syringe 100 (i.e., directly
Footpath) select the spacing.Narrow cylinder 1 discharges less amount it is meant that given stroke for plunger 2 from syringe 100, and
And a certain amount of injected material must be correspondingly represented using the flange of larger spacing.Furthermore it is possible to plunger rod 3 is embodied as
Hollow stem.Plunger rod 3 can be manufactured by injection-molded, and if plunger rod 3 is made into solid, then the product is cold
But by it is relatively time consuming with avoid shrink the problem of, between contraction problem and then the tolerance issues that flange can be caused, i.e. flange away from
From changing and the protuberance of flange changes.Such tolerance variation is undesirable naturally and is typically not allow
Perhaps.Therefore, plunger rod 3 can be made hollow, which save material and remedy these coolings and tolerance issues.Injection
Device 100 further comprises the compartment 11 substantially limited by cylindrical external component 18 and cylindrical interior element 12 and is arranged at institute
State the engagement member 4 in compartment 11.It is natural, it is contemplated that the compartment 11 of other shapes, for example (,) it is square, oval etc..Shown in Fig. 1
Embodiment in, engagement member 4 includes semi-circle shaped elements 6, prominent element 7 and adjustment member 15.Engagement member 4 is arranged
In compartment 11, its mode for cause prominent element 7 extend through the opening 13 in cylindrical interior element 12 and with plunger rod 3
Grooved surfaces 5 engage.Typically, engagement member 4 by maintenance in compartment 11 so that it can be along perpendicular to plunger
Move but be prevented from along the direction of the longitudinal direction parallel to plunger rod 3 to a certain extent in the direction of the longitudinal direction of bar 3
Carry out any movement.This maintenance can be provided with various ways.For example, as shown in figure 5, lid 19 can be provided so that
Engagement member 4 moved freely through on the direction vertical with the longitudinal direction of plunger rod 3 in the compartment 11 but be prevented from along with
The direction that the longitudinal direction of plunger rod 3 is parallel carries out any movement.Other suitable means are the lines of rabbet joint, and engagement member 4 can lead to
Cross tight fit or press-fit or engagement member 4 is locked into snap lock mode in place and insert in these lines of rabbet joint.When user just
When giving medical treatment material and therefore plunger rod 3 being pushed further into cylinder 1, due to these flanges through engagement member 4 from
And direction of the engagement member 4 along the longitudinal direction perpendicular to plunger rod 3 is moved, sound is generated, this is in the form of click sound
And feedback can also be provided to user in the form of touch feedback.User easily study will click on sound and medical treatment material to
The amount of giving is associated and also that the sound is associated with some charge velocity, thus allows user exactly for the material
It is administered and it is distributed as needed.The major advantage that the motor pattern of the engagement member 4 of the present invention has exists
In a sound click sound represents the initial set dosage corresponding with one click all the time.In some prior art solutions
In, problems be present in engagement member:Engagement member can be biased, simultaneously in opposite direction during suction or inhaled material
And in injecting the first dose procedure required before producing the first click sound plunger rod advance must than for one click institute at the beginning of
Begin set much farther away.It has been shown that the first dosage of prior art syringe is probably set up to three times in test.This
The excessive dosage of sample is certainly very undesirable and may have devastating impact in some cases.Pass through this patent Shen
Solution of the invention that please be common to all embodiments, no matter plunger rod 3 drives plunger 2 along which direction, engages structure
Part 4 moves back and forth to and fro between two given turning points all the time, and engagement member 4 is in the wrong direction without inclined
Put, but alternatively, when plunger rod 3 moves, the protrusion element 7 of engagement member 4 is all the time in the table with groove of plunger rod 3
Slided on face 5.This may be best shown in figs 4 a and 4b.It is distinct right that this is formed with mentioned prior art solution
Than, wherein, engagement member is only shelved in the grooved surfaces of the plunger rod simultaneously during the Part I of the first dosage
And as it advances, until it eventually arrives at the mobile position started with actual click function of slip of the engagement member.In Fig. 1
In shown embodiment, the protrusion element 7 of engagement member 4 folds from main body 6.Engagement member 4 is typically by with about 0.03-
The metal of 0.5mm thickness is made.The height (that is, along the extension in the direction of the longitudinal direction parallel to plunger rod 3) of prominent element 7
It is selected to be large enough to avoid in use, the direction of longitudinal direction of the prominent element 7 along parallel plunger rod 3 is curved
Folding.Alternatively, the interaction between the movement of plunger rod 3 and grooved surfaces 5 and prominent element 7 will only cause prominent
Go out element 7 and therefore direction of the whole engagement member 4 along the longitudinal direction perpendicular to plunger rod 3 is moved.Typically, prominent member
The height of part 7 is between 1-10mm.Therefore, it is also likely to be suitable to provide reduced portion to end 10.End 10 it is tapered, with it is right
The appropriate preload (prominent element 7 is pressed against in grooved surfaces 5 with serving as spring) of main body 6 is combined also have with
Lower effect:When user discharges the power to the application of plunger rod 3, during such as inhaled material, plunger rod 3 makes presentation
Tapered end 10 is shelved on the position of bottom between two ridges of grooved surfaces 5.Material is being sucked it in cylinder 1 by this
Can be especially advantageous afterwards, because the dosage clicked on for the first time in this case will be set big, also not unlike initial
It is smaller.Under any circumstance, the prestressing force of main body 6 should be large enough to ensure, prominent element 7 rests against with recessed all the time
On the surface 5 of groove, so as to produce click sound all the time when plunger rod moves.In the embodiment shown in fig. 1, can be appointed by edge
One direction presses adjustment member 15 to turn off click function, therefore causes engagement member 4 in the internal rotation of compartment 11.This will have with
Lower effect:Prominent element 7 leaves opening 13 and is therefore no longer in contact with grooved surfaces 5.
In the embodiment shown in Figure 2, there is provided the engagement member 4 of plate-like component form, the tabular component have master
Body 6 and the protrusion element 7 folded from main body 6.On the thickness of engagement member 4 and the height of prominent element 7, with reference to Fig. 1
Described is equally applicable.Certainly, other suitable modes can also realize prominent element 7.For example, by welding or it is gluing come
The prominent element of attachment;Welding spark is provided on the surface of main body 6;It is first-class that sufficiently rigid tenon or pin are attached to main body 6.Fig. 2
Engagement member 4 can be attached at by the multiple lines of rabbet joint (shown in Fig. 2 but do not have reference) being arranged in compartment 11
In compartment 11, it is fitted close or is press-fitted or these lines of rabbet joint are too narrow to be enough to provide with two opposite edges of tabular engagement member 4
Close, otherwise these lines of rabbet joint can be equipped with engagement member 4 to be locked to snap lock in place.Tight fit or press-fit or snap lock
The advantages of being respectively provided with is simple and allows to manufacture cheaply.Naturally it is also contemplated that for example gluing, thermal weld or using single
The means such as attachment arrangement.Focus on, prevent direction of the engagement member 4 along the longitudinal direction parallel to plunger rod 3 from moving.This works as
So it is applied to all embodiments of the present invention.
In the embodiment shown in fig. 3, there is provided the engagement member 4 of the form of semicircular in shape continuous elements.Instead of from master
Body 6 folds, and prominent element 7 is created as the continuation of main body 6 but has narrower crooked process radius in this embodiment,
So that end 10 will abut the grooved surfaces 5 of plunger rod 3.It should be noted that prominent element 7 need not be folded into as far as sensing
The radial direction of plunger rod 3;Point to it is sufficient that direction of the string in the section of plunger rod 3 in the end 10 of prominent element 7.Such as Fig. 2
Shown, the size and material with reference to mentioned by Fig. 1 are equally applicable herein.
Fig. 4 a and 4b disclose the side cross-sectional view of the embodiment from Fig. 1, which show engagement member 4 due to plunger
The movement of bar 3 and what is carried out move back and forth.Such as from these figures it can be readily appreciated that the present invention solution avoid from
In prior art solution known engagement member along the opposite way round bias the shortcomings that.In addition, in figs 4 a and 4b, describe
A kind of shape being contemplated that of these flanges of grooved surfaces 5.However, this is only exemplary, because in appended right
It is also contemplated that many other shapes in the range of it is required that.
Fig. 5 shows the perspective view of syringe according to an embodiment of the invention.Here, engagement is realized by lid 5
The maintenance of the (not shown) of component 4.As described earlier, this maintenance can also be completed with many other modes.
It is such to show and retouch although being shown in detail in accompanying drawing and above description and having described the present invention
State should be interpreted it is illustrative or exemplary and not restrictive;The invention is not restricted to disclosed embodiment.This area
Technical staff can be managed when putting into practice invention claimed by learning accompanying drawing, disclosure content and appended claims
Solve and complete other changes of disclosed embodiment.In the claims, word " comprising " is not excluded for other key elements or step
Suddenly, and indefinite article "one" be not precluded from it is multiple.Quote in mutually different dependent claims some measures this
The fact that simple, is not offered as, it is impossible to advantageously using the combination of these measures.Any reference in the claims is all
It is not necessarily to be construed as limiting the scope of claim.
The injection of botulin toxin is to use field as the possibility of the apparatus according to the invention and refer to.Certainly,
The apparatus according to the invention can be used for other fluid compositions and gel combination (for example, hydrogel).The device
Available for injection crosslinking or noncrosslinking hyaluronic acid derivatives and it is not that the other kinds of of hyaluronic acid is subcutaneously filled
Agent, such as collagen, calcium hydroxy apetite, Poly-L-lactide (PLLA), other polysaccharide and polymethyl methacrylate (PMMA).This
Outside, the device can be used for injection comprising active material and/or bioactivator (for example, local anesthetic, cicarisantia, anti-oxidant
Agent, insulin or growth hormone) fluid composition.A kind of such preferable fluid composition is with hyalomitome
Acid gel carrier and active material and/or bioactivator (such as local anesthetic or cicarisantia, such as dextranomer pearl) it is solidifying
Glue composition.
Claims (15)
1. a kind of syringe (100), the syringe include:Cylinder (1);The plunger (2) that is movably arranged in the cylinder (1) and
For driving the plunger rod (3) of the plunger (2);And engagement member (4), the engagement member are arranged at the cylinder (1) and sentenced
Engaged with the grooved surfaces (5) on the plunger rod (3) so that when the plunger rod (3) is moved to drive relative to the cylinder (1)
When moving plunger (2), feedback is provided to user, wherein the cylinder (1) and the engagement member (4) are pacified relative to each other
Line up so that, when the plunger rod (3) is mobile relative to the cylinder (1), the engagement member (4) is due to the band with the plunger rod (3)
The surface (5) of groove engages and only moved along the direction for the longitudinal direction for being generally orthogonal to the plunger rod (3).
2. syringe (100) according to claim 1, wherein, the engagement member (4) is arranged in the cylinder (1).
3. syringe (100) according to claim 1 or 2, wherein, the engagement member (4) be arranged at cylinder (1) place,
It is immovable on the direction of the longitudinal direction parallel to the plunger rod (3).
4. syringe (100) according to claim 3, wherein, the engagement member (4) can not in the described of cylinder (1) place
Mobile arrangement is realized by the tight fit between the engagement member (4) and the cylinder (1).
5. syringe (100) according to claim 3, wherein, the engagement member (4) can not in the described of cylinder (1) place
Mobile arrangement is realized by snap-lock.
6. syringe (100) according to claim 3, wherein, the engagement member (4) can not in the described of cylinder (1) place
Mobile arrangement is realized by being arranged at the lid (8) at cylinder (1) place.
7. the syringe (100) according to any one of the preceding claims, wherein, the engagement member (4) includes having circle
The main body of shape or semicircular in shape (6) and prominent to engage the grooved surfaces of the plunger rod (3) from the main body (6)
(5) protrusion element (7).
8. syringe (100) according to any one of claim 1 to 6, wherein, the engagement member (4) is included generally
It is the main body (6) of tabular and is protruded from the main body (6) to engage the protrusion of the grooved surfaces (5) of the plunger rod (3)
Element (7).
9. the syringe (100) according to claim 7 or 8, wherein, the prominent element (7) is along the protrusion element (7)
Edge (9) be connected in the main body (6), the edge (9) be generally parallel to the plunger rod (3) longitudinal direction extension.
10. syringe (100) according to claim 9, wherein, the master of the protrusion element (7) from the engagement member (4)
Body (6) folds along the edge (9).
11. the syringe (100) according to any one of claim 7 to 10, wherein, the prominent element (7) is from this
What the main body (6) of engagement member (4) stamped out.
12. syringe (100) according to any one of claim 1 to 6, wherein, the engagement member (4) includes having half
Round-shaped main body (6) and prominent element (7), wherein the protrusion element (7) are arranged to the extension, simultaneously of the main body (6)
And there is the crooked process radius more narrower than the main body (6) so that the end (10) of the protrusion element (7) engages the plunger rod (3)
Grooved surfaces (5).
13. the syringe (100) according to any one of the preceding claims, wherein, the engagement member (4) is arranged at this
Cylinder (1), be generally configured in the compartment of annulation (11), wherein the plunger rod (3) extends through the inner circle of the annulation
(12), and wherein the engagement member (4) can pass through the opening (13) in the compartment (11) engage the plunger rod (3) band it is recessed
The surface (5) of groove.
14. syringe (100) according to claim 8, wherein, the plate-like body (6) of the engagement member (4) is along the plate
Two edges of shape main body (6) are attached on the cylinder (1).
15. the syringe (100) according to any one of the preceding claims, wherein, the engagement member (4), with the post
The end (10) that the grooved surfaces (5) of stopper rod (3) engage has tapered portion so that no matter the movement of the plunger rod (3)
How is direction, all provides feedback to user.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15160799.1A EP3072547B1 (en) | 2015-03-25 | 2015-03-25 | Syringe with track-indexed plunger rod |
EP15160799.1 | 2015-03-25 | ||
PCT/EP2016/056559 WO2016151091A1 (en) | 2015-03-25 | 2016-03-24 | Track-indexed syringe |
Publications (1)
Publication Number | Publication Date |
---|---|
CN107567340A true CN107567340A (en) | 2018-01-09 |
Family
ID=52875465
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201680026701.XA Pending CN107567340A (en) | 2015-03-25 | 2016-03-24 | Track indexing syringe |
Country Status (18)
Country | Link |
---|---|
US (1) | US10835684B2 (en) |
EP (2) | EP3072547B1 (en) |
JP (1) | JP2018509246A (en) |
KR (1) | KR20170139033A (en) |
CN (1) | CN107567340A (en) |
AU (1) | AU2016238801A1 (en) |
BR (1) | BR112017020485A2 (en) |
CA (1) | CA2980645A1 (en) |
DK (1) | DK3072547T3 (en) |
ES (1) | ES2712301T3 (en) |
HR (1) | HRP20190130T1 (en) |
HU (1) | HUE042546T2 (en) |
MX (1) | MX2017012253A (en) |
PL (1) | PL3072547T3 (en) |
PT (1) | PT3072547T (en) |
RU (1) | RU2017136166A (en) |
SI (1) | SI3072547T1 (en) |
WO (1) | WO2016151091A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9504603B2 (en) | 2012-04-02 | 2016-11-29 | Ocuject, Llc | Intraocular delivery devices and methods therefor |
EP2783720A1 (en) * | 2013-03-28 | 2014-10-01 | Q-Med AB | Track-indexed syringe |
WO2018191101A1 (en) * | 2017-04-13 | 2018-10-18 | Becton, Dickinson And Company | Controlled delivery syringe device |
RU2696451C1 (en) * | 2019-03-27 | 2019-08-01 | Общество с ограниченной ответственностью «НЭКСТ БИО» | Injection syringe |
RU2700459C1 (en) * | 2019-04-03 | 2019-09-17 | Общество с ограниченной ответственностью «НЭКСТ БИО» | Device for drug delivery |
RU2729442C1 (en) * | 2019-10-23 | 2020-08-06 | Общество с ограниченной ответственностью "НЭКСТ БИО" | Device for drug delivery |
US20230226280A1 (en) * | 2020-09-25 | 2023-07-20 | Ocuject, Llc | Syringe injector with a feedback mechanism |
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2015
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- 2015-03-25 PL PL15160799T patent/PL3072547T3/en unknown
- 2015-03-25 DK DK15160799.1T patent/DK3072547T3/en active
- 2015-03-25 ES ES15160799T patent/ES2712301T3/en active Active
- 2015-03-25 EP EP15160799.1A patent/EP3072547B1/en active Active
- 2015-03-25 PT PT15160799T patent/PT3072547T/en unknown
- 2015-03-25 HU HUE15160799A patent/HUE042546T2/en unknown
-
2016
- 2016-03-24 KR KR1020177030802A patent/KR20170139033A/en unknown
- 2016-03-24 CN CN201680026701.XA patent/CN107567340A/en active Pending
- 2016-03-24 US US15/560,593 patent/US10835684B2/en active Active
- 2016-03-24 CA CA2980645A patent/CA2980645A1/en not_active Abandoned
- 2016-03-24 BR BR112017020485A patent/BR112017020485A2/en not_active Application Discontinuation
- 2016-03-24 MX MX2017012253A patent/MX2017012253A/en unknown
- 2016-03-24 EP EP16711660.7A patent/EP3274029A1/en active Pending
- 2016-03-24 RU RU2017136166A patent/RU2017136166A/en not_active Application Discontinuation
- 2016-03-24 AU AU2016238801A patent/AU2016238801A1/en not_active Abandoned
- 2016-03-24 WO PCT/EP2016/056559 patent/WO2016151091A1/en active Application Filing
- 2016-03-24 JP JP2017549737A patent/JP2018509246A/en active Pending
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2019
- 2019-01-21 HR HRP20190130TT patent/HRP20190130T1/en unknown
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Also Published As
Publication number | Publication date |
---|---|
HRP20190130T1 (en) | 2019-03-08 |
BR112017020485A2 (en) | 2018-07-03 |
AU2016238801A1 (en) | 2017-10-26 |
KR20170139033A (en) | 2017-12-18 |
EP3072547B1 (en) | 2019-01-02 |
RU2017136166A (en) | 2019-04-25 |
EP3072547A1 (en) | 2016-09-28 |
HUE042546T2 (en) | 2019-07-29 |
US10835684B2 (en) | 2020-11-17 |
SI3072547T1 (en) | 2019-03-29 |
MX2017012253A (en) | 2018-06-06 |
EP3274029A1 (en) | 2018-01-31 |
US20180085529A1 (en) | 2018-03-29 |
PL3072547T3 (en) | 2019-05-31 |
DK3072547T3 (en) | 2019-03-11 |
JP2018509246A (en) | 2018-04-05 |
CA2980645A1 (en) | 2016-09-29 |
WO2016151091A1 (en) | 2016-09-29 |
ES2712301T3 (en) | 2019-05-10 |
RU2017136166A3 (en) | 2019-05-23 |
PT3072547T (en) | 2019-02-26 |
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Application publication date: 20180109 |