CN107551403B - Magnetic stimulation blood pressure reduction equipment through carotid sinus - Google Patents
Magnetic stimulation blood pressure reduction equipment through carotid sinus Download PDFInfo
- Publication number
- CN107551403B CN107551403B CN201710928911.4A CN201710928911A CN107551403B CN 107551403 B CN107551403 B CN 107551403B CN 201710928911 A CN201710928911 A CN 201710928911A CN 107551403 B CN107551403 B CN 107551403B
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- China
- Prior art keywords
- magnetic stimulation
- blood pressure
- pulse generator
- sinus
- water cooling
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- 230000000638 stimulation Effects 0.000 title claims abstract description 85
- 210000001326 carotid sinus Anatomy 0.000 title claims abstract description 30
- 230000036772 blood pressure Effects 0.000 title claims abstract description 29
- 230000009467 reduction Effects 0.000 title claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 37
- 238000001816 cooling Methods 0.000 claims abstract description 32
- 238000002955 isolation Methods 0.000 claims abstract description 16
- 239000003990 capacitor Substances 0.000 claims description 10
- 238000007599 discharging Methods 0.000 claims description 10
- 239000004973 liquid crystal related substance Substances 0.000 claims description 10
- 239000013013 elastic material Substances 0.000 claims description 5
- 239000004698 Polyethylene Substances 0.000 claims description 3
- 229920000915 polyvinyl chloride Polymers 0.000 claims description 3
- 239000004800 polyvinyl chloride Substances 0.000 claims description 3
- 229920001169 thermoplastic Polymers 0.000 claims description 3
- 239000004416 thermosoftening plastic Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 2
- -1 polyethylene Polymers 0.000 claims description 2
- 229920000573 polyethylene Polymers 0.000 claims description 2
- 229920001296 polysiloxane Polymers 0.000 claims 2
- 206010020772 Hypertension Diseases 0.000 abstract description 6
- 238000005516 engineering process Methods 0.000 abstract description 5
- 238000001356 surgical procedure Methods 0.000 abstract description 4
- 238000010586 diagram Methods 0.000 description 7
- 238000000034 method Methods 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 108091008698 baroreceptors Proteins 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000005674 electromagnetic induction Effects 0.000 description 2
- 210000001774 pressoreceptor Anatomy 0.000 description 2
- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 239000002220 antihypertensive agent Substances 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 210000000748 cardiovascular system Anatomy 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 208000031225 myocardial ischemia Diseases 0.000 description 1
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- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
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- Magnetic Treatment Devices (AREA)
Abstract
The invention provides a magnetic stimulation blood pressure lowering device through carotid sinus, comprising: the pulse generator, the circulating water cooling case, the handle, the magnetic stimulation coil, the isolation pad, the cable, U type clamp and water-cooled tube. The magnetic stimulation blood pressure lowering device through the carotid sinus can treat hypertension by utilizing the principle that the carotid sinus is sensitive to physical stimulation. The magnetic stimulation coil is not directly contacted with tissues, so that potential safety hazards caused by similar electrical stimulation technologies can be avoided, and invasive surgery is not needed.
Description
Technical Field
The invention relates to the technical field of medical instruments for treating hypertension, in particular to a magnetic stimulation blood pressure lowering device through carotid sinus.
Background
Hypertension is a common cardiovascular disease, and 54% of strokes and 47% of ischemic heart diseases are caused by elevated blood pressure. However, existing hypotensive agents have no significant effect on patients with hypertension exceeding 1/3, and therefore, the development of novel therapeutic techniques is of great clinical significance. There are sensory nerve endings, called baroreceptors, that are sensitive to mechanical stretch stimuli under the intima of the carotid sinus vessel wall. The internal pressure of the carotid sinus can be changed by physically stimulating the baroreceptors, thereby playing a role in regulating the cardiovascular system. The electrical stimulation of the carotid sinus is an effective means for treating refractory hypertension and has great application potential in clinic. However, this technique requires the electrodes to be implanted in the neck and attached to the wall of the vessel of the unilateral or bilateral carotid sinus, while the electrical pulse generator and connecting leads also need to be implanted subcutaneously. Although electrical stimulation of the carotid sinus can significantly reduce blood pressure, clinical application of this technique requires invasive surgery and multiple safety considerations, with high surgical difficulty, high cost and significant patient pain.
Disclosure of Invention
Therefore, the invention provides a magnetic stimulation blood pressure lowering device through the carotid sinus, which can treat hypertension by using a method of electrically stimulating the carotid sinus without operation.
The invention provides a magnetic stimulation blood pressure lowering device through carotid sinus, comprising: the device comprises a pulse generator, a circulating water cooling box, a handle, a magnetic stimulation coil, an isolation pad, a cable, a U-shaped clamp and a water cooling pipe; the cable connected to the pulse generator penetrates through the inner cavities of the handle and the U-shaped clamp to be connected with the magnetic stimulation coil, the water cooling pipe connected to the circulating water cooling box penetrates through the inner cavities of the handle and the U-shaped clamp to be connected with the magnetic stimulation coil, the handle is connected with the magnetic stimulation coil through the U-shaped clamp, the handle is connected to the middle of the U-shaped clamp, the magnetic stimulation coil is connected to the two ends of the U-shaped clamp, the isolation pad is connected to the head of the magnetic stimulation coil, and the U-shaped clamp is made of elastic materials.
Furthermore, the pulse generator comprises a charging circuit, a discharging loop and a central control circuit, and the central control circuit is in control connection with the charging circuit and the discharging loop; the charging circuit is connected with a transformer, a rectifier bridge, a charging switch and a current-limiting resistor; the discharging loop is connected with a storage capacitor bank and a discharging switch, and the discharging loop is also connected with the magnetic stimulation coil.
Further, the input alternating voltage of the transformer is 220V, the output alternating voltage is 2000V, and the rated power is lower than 300 VA.
Further, the storage capacitor bank is composed of one or more capacitors, the internal wiring inductance is less than 5 muH, and the total capacitance is in the range of 200 to 500 muF.
Further, the magnetic stimulation coil is cylindrical, and the diameter of the bottom surface of the magnetic stimulation coil is 3cm-7 cm.
Further, the peak magnetic field of the time-varying magnetic field generated by the pulse generator is in the range of 1T to 3T, the gradient of the time-varying magnetic field is less than 50Gs/cm, and the magnetic stimulation frequency range of the pulse generator is between 0.5HZ and 100 HZ.
Furthermore, a liquid crystal display screen is arranged on the front side of the pulse generator, an up-down selection button is arranged on the right side of the liquid crystal display screen, 3-5 shortcut selection keys are arranged on the lower side of the liquid crystal display screen, and a cable BNC interface is arranged on the left lower side of the front side of the pulse generator; the back of the pulse generator is provided with a first power interface and a first power switch.
Furthermore, a water inlet and a water outlet are formed in the front face of the circulating water cooling box, and a fan, a second power supply interface and a second power supply switch are arranged on the back face of the circulating water cooling box.
Further, the outside of handle is provided with intensity adjustment knob, shift knob and pilot lamp.
Furthermore, the isolation pad is made of thermoplastic vulcanized silica gel, and the water cooling pipe is made of polyvinyl chloride, polyethylene or silicone resin.
Compared with the traditional carotid sinus electrical stimulation technology, the magnetic stimulation blood pressure lowering device through the carotid sinus can generate high, medium and low frequency magnetic fields through time-varying current, penetrate tissues and focus to the carotid sinus, and generate treatment eddy current due to electromagnetic induction. The magnetic stimulation coil is not directly contacted with tissues, so that potential safety hazards caused by similar electrical stimulation technologies can be avoided, and invasive surgery is not needed.
Additional aspects and advantages of the invention will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the invention.
Drawings
FIG. 1 is a schematic structural diagram of a magnetic stimulation blood pressure lowering device through carotid sinus according to an embodiment of the present invention;
FIG. 2 is a schematic front view of a pulse generator of a magnetic stimulation blood pressure lowering device via carotid sinus according to an embodiment of the present invention;
FIG. 3 is a schematic diagram of a back structure of a pulse generator of a magnetic stimulation blood pressure lowering device via carotid sinus according to an embodiment of the present invention;
FIG. 4 is a schematic circuit diagram of a pulse generator of a transcervical sinus magnetic stimulation blood pressure lowering device according to an embodiment of the present invention;
FIG. 5 is a schematic front view of a circulating water cooling tank of a magnetic stimulation blood pressure lowering device via carotid sinus according to an embodiment of the present invention;
FIG. 6 is a schematic diagram of the back structure of a circulating water cooling tank of a magnetic stimulation blood pressure lowering device via carotid sinus according to an embodiment of the present invention;
FIG. 7 is a schematic structural diagram of a handle of a transcervical sinus magnetic stimulation blood pressure lowering device according to an embodiment of the present invention;
FIG. 8 is a schematic diagram of a side connection structure of a magnetic stimulation coil and an isolation pad of a magnetic stimulation blood pressure lowering device through a carotid sinus according to an embodiment of the invention;
fig. 9 is a schematic diagram of a front connection structure of the magnetic stimulation coil and the isolation pad of the magnetic stimulation blood pressure lowering device through the carotid sinus according to the embodiment of the invention.
In the drawings are labeled:
1 pulse generator
2 circulating water cooling tank
3 handle
4 magnetic stimulation coil
5 isolating pad
6 water-cooling tube
7 Cable
8 cable BNC interface
9 liquid crystal display screen
10 Up-down selection button
11 shortcut selection key
12 first power switch
13 first power interface
14 transformer
15 charging circuit
16 storage capacitor bank
17 discharge circuit
18 central control circuit
19 water inlet
20 water outlet
21 second power interface
22 second power switch
23 Fan
24 switch button
25 indicating lamp
26 intensity adjusting knob
27U-shaped clamp
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the drawings are illustrative and intended to be illustrative of the invention and are not to be construed as limiting the invention.
An embodiment of the present invention provides a magnetic stimulation blood pressure lowering device through carotid sinus, as shown in fig. 1, including: the device comprises a pulse generator 1, a circulating water cooling tank 2, a handle 3, a magnetic stimulation coil 4, an isolation pad 5, a cable 7, a U-shaped clamp 27 and a water cooling pipe 6; the cable 7 connected to the pulse generator 1 passes through the inner cavities of the handle 3 and the U-shaped clamp 27 to be connected with the magnetic stimulation coil 4, the water cooling pipe 6 connected to the circulating water cooling box 2 passes through the inner cavities of the handle 3 and the U-shaped clamp 27 to be connected with the magnetic stimulation coil 4, the handle 3 is connected with the magnetic stimulation coil 4 through the U-shaped clamp 27, the handle 3 is connected to the middle part of the U-shaped clamp 27, the magnetic stimulation coil 4 is connected to two ends of the U-shaped clamp 27, the isolation pad 5 is connected to the head part of the magnetic stimulation coil 4, and the U-shaped clamp 27 is made of elastic materials.
As shown in fig. 4, the pulse generator 1 includes a charging circuit 15, a discharging circuit 17, and a central control circuit 18, where the central control circuit 18 is in control connection with the charging circuit 15 and the discharging circuit 17, and optionally, may further include a display circuit for ensuring that the display screen 9 performs display; the charging circuit 15 is connected with a transformer 14, and is also connected with a rectifier bridge, a charging switch and a current-limiting resistor in a matching way; the discharge circuit 17 is connected with a storage capacitor bank 16 and the magnetic stimulation coil 4, and is also connected with a discharge switch in a matching manner, in one embodiment of the present invention, the discharge switch is disposed on the handle 3, for example, as shown in fig. 7, a switch button 24 on the handle is used for switching on and off the discharge circuit, and an intensity adjusting knob 26 is used for adjusting the magnitude of the discharge electric quantity; meanwhile, an indicator light 25 is arranged beside the switch button 24, and the indicator light 25 is green when in normal operation and is in an off state or red when in fault.
Preferably, the input alternating voltage of the transformer 14 is 220V, the output alternating voltage is 2000V, and the rated power is lower than 300 VA. The storage capacitor bank 16 is comprised of one or more capacitors having an internal wiring inductance of less than 5 muh and a total capacitance in the range of 200 to 500 muf. The magnetic stimulation coil 4 is cylindrical, and the diameter of the bottom surface of the magnetic stimulation coil is 3cm-7 cm. The peak magnetic field of the time-varying magnetic field generated by the pulse generator 1 is in the range of 1T to 3T, the gradient of the time-varying magnetic field is less than 50Gs/cm, and the magnetic stimulation frequency range of the pulse generator is between 0.5HZ and 100 HZ. The carotid sinus is small in size and close to the body surface, a time-varying magnetic field does not need to penetrate through excessively complex tissues, and in order to ensure that a magnetic stimulation coil has effective focusing power and stimulation depth, the number of the coil turns is set to be 5-10 turns, and the diameter is 3cm-7 cm. During specific work, the pulse generator 1 is connected to the magnetic stimulation coil 4 through the cable 7, the circulating water cooling box 2 is connected with the water cooling pipe 6 to continuously suck and discharge water flow so as to reduce the heat of the magnetic stimulation coil 4, the handle 3 is connected to the tail of the magnetic stimulation coil 4, the isolation pad 5 is installed at the head of the magnetic stimulation coil 4 to avoid the direct contact of the surface of the magnetic stimulation coil 4 and the skin, as shown in fig. 8 and 9, the isolation pad 5 is horn-shaped, and a concave part matched with the shape of the neck is formed in the position contacted with the human body, so that the neck skin of the human body can be closely combined. The isolation pad 5 can be mechanically taken out for disinfection and cleaning, and is made of thermoplastic vulcanized silica gel material. The water-cooling tube 6 is made of polyvinyl chloride, polyethylene or silicon resin so as to ensure that the water-cooling tube 6 has good heat conductivity.
In one aspect of the embodiment of the present invention, as shown in fig. 2 and 3, the front of the pulse generator 1 has a liquid crystal display screen 9, the right side of the liquid crystal display screen 9 has an up-down selection button 10, the lower side of the liquid crystal display screen 9 is provided with 3 to 5 shortcut selection keys 11, and the left lower side of the front of the pulse generator 1 is provided with a cable BNC interface 8; the back of the pulse generator 1 is provided with a first power interface 13 and a first power switch 12. As shown in fig. 5 and 6, the front surface of the circulating water cooling tank 2 is provided with a water inlet 19 and a water outlet 20 for sucking and discharging water in the tank body; a fan 23 is arranged on the back of the circulating water cooling tank 2 and used for dissipating heat; a second power interface 21 and a second power switch 22.
Compared with the traditional carotid sinus electrical stimulation technology, the magnetic stimulation blood pressure lowering device through the carotid sinus can generate high, medium and low frequency magnetic fields through time-varying current, penetrate tissues and focus to the carotid sinus, and generate treatment eddy current due to electromagnetic induction. The magnetic stimulation coil is not directly contacted with tissues, so that potential safety hazards caused by similar electrical stimulation technologies can be avoided, and invasive surgery is not needed.
Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention, and that variations, modifications, substitutions and alterations can be made to the above embodiments by those of ordinary skill in the art within the scope of the present invention.
Claims (8)
1. A transcervical sinus magnetic stimulation blood pressure lowering device, comprising:
the device comprises a pulse generator, a circulating water cooling box, a handle, a magnetic stimulation coil, an isolation pad, a cable, a U-shaped clamp and a water cooling pipe;
the cable connected to the pulse generator penetrates through the handle and the inner cavity of the U-shaped clamp to be connected with the magnetic stimulation coil, the water cooling pipe connected to the circulating water cooling box penetrates through the handle and the inner cavity of the U-shaped clamp to be connected with the magnetic stimulation coil, the handle is connected with the magnetic stimulation coil through the U-shaped clamp, the handle is connected to the middle of the U-shaped clamp, the magnetic stimulation coil is connected to two ends of the U-shaped clamp, the isolation pad is connected to the head of the magnetic stimulation coil, and the U-shaped clamp is made of elastic materials; the isolation pad is in a horn shape, and a concave part matched with the shape of the neck is arranged at the position where the isolation pad is contacted with a human body;
the pulse generator comprises a charging circuit, a discharging loop and a central control circuit, and the central control circuit is in control connection with the charging circuit and the discharging loop;
the charging circuit is connected with a transformer, a rectifier bridge, a charging switch and a current-limiting resistor;
the discharge loop is connected with a storage capacitor bank and a discharge switch, and is also connected with the magnetic stimulation coil;
the peak magnetic field of the time-varying magnetic field generated by the pulse generator is in the range of 1T to 3T, the gradient of the time-varying magnetic field is less than 50Gs/cm, and the magnetic stimulation frequency range of the pulse generator is between 0.5HZ and 100 HZ.
2. The transcervical sinus magnetic stimulation blood pressure reduction device according to claim 1, wherein the transformer has an input ac voltage of 220V and an output ac voltage of 2000V, and has a rated power of less than 300 VA.
3. The transcervical sinus magnetic stimulation blood pressure lowering device according to claim 1, wherein the storage capacitor bank is comprised of one or more capacitors, an internal wiring inductance is less than 5 μ H, and a total capacitance is in a range of 200 to 500 μ F.
4. The transcervical sinus magnetic stimulation blood pressure reduction device according to claim 1, wherein the magnetic stimulation coil is cylindrical and has a bottom surface with a diameter of 3cm to 7 cm.
5. The transcervical sinus magnetic stimulation blood pressure reduction device according to claim 1, wherein the front of the pulse generator is provided with a liquid crystal display screen, the right side of the liquid crystal display screen is provided with an up-down selection button, the lower side of the liquid crystal display screen is provided with 3 to 5 shortcut selection buttons, and the left lower side of the front of the pulse generator is provided with a cable BNC interface; the back of the pulse generator is provided with a first power interface and a first power switch.
6. The transcervical carotid sinus magnetic stimulation blood pressure reduction device according to claim 1, wherein the front surface of the circulating water cooling tank is provided with a water inlet and a water outlet, and the back surface of the circulating water cooling tank is provided with a fan, a second power interface and a second power switch.
7. The transcervical sinus magnetic stimulation blood pressure reduction device according to claim 1, wherein the handle is provided at an outer side thereof with an intensity adjustment knob, a switch button and an indicator light.
8. The transcervical sinus magnetic stimulation blood pressure reduction device according to claim 1, wherein the isolation pad is made of thermoplastic vulcanized silicone material, and the water cooling tube is made of polyvinyl chloride, polyethylene or silicone.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710928911.4A CN107551403B (en) | 2017-10-09 | 2017-10-09 | Magnetic stimulation blood pressure reduction equipment through carotid sinus |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710928911.4A CN107551403B (en) | 2017-10-09 | 2017-10-09 | Magnetic stimulation blood pressure reduction equipment through carotid sinus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107551403A CN107551403A (en) | 2018-01-09 |
| CN107551403B true CN107551403B (en) | 2021-06-29 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710928911.4A Expired - Fee Related CN107551403B (en) | 2017-10-09 | 2017-10-09 | Magnetic stimulation blood pressure reduction equipment through carotid sinus |
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| Country | Link |
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| CN (1) | CN107551403B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110354393A (en) | 2018-03-26 | 2019-10-22 | 郑云峰 | Nervous centralis magnetic stimulating device |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2257727Y (en) * | 1996-09-04 | 1997-07-16 | 祝强 | Hypertension instrument |
| CN203253060U (en) * | 2013-03-04 | 2013-10-30 | 深圳英智科技有限公司 | Water-circulation cooling apparatus outside magnetic stimulation coil |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009018394A1 (en) * | 2007-07-31 | 2009-02-05 | Schneider M Bret | Device and method for hypertension treatment by non-invasive stimulation to vascular baroreceptors |
| CN102145203B (en) * | 2010-02-10 | 2015-01-14 | 赵维平 | Hand-held palm electrical pulse therapeutic equipment for treating symptoms of hypertension, hyperglycemia and hyperlipemia |
-
2017
- 2017-10-09 CN CN201710928911.4A patent/CN107551403B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2257727Y (en) * | 1996-09-04 | 1997-07-16 | 祝强 | Hypertension instrument |
| CN203253060U (en) * | 2013-03-04 | 2013-10-30 | 深圳英智科技有限公司 | Water-circulation cooling apparatus outside magnetic stimulation coil |
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| Publication number | Publication date |
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| CN107551403A (en) | 2018-01-09 |
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Granted publication date: 20210629 |