CN107536950A - A kind of pharmaceutical composition for treating numbness disease, skin disease and gynaecological disease and its production and use - Google Patents

A kind of pharmaceutical composition for treating numbness disease, skin disease and gynaecological disease and its production and use Download PDF

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Publication number
CN107536950A
CN107536950A CN201610515026.9A CN201610515026A CN107536950A CN 107536950 A CN107536950 A CN 107536950A CN 201610515026 A CN201610515026 A CN 201610515026A CN 107536950 A CN107536950 A CN 107536950A
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China
Prior art keywords
parts
disease
pharmaceutical composition
bulk drug
treatment
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CN201610515026.9A
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Chinese (zh)
Inventor
白玛卓嘎
江吉村
强文社
江华
扎西彭措
党知才仁
白玛郎甲
其麦英珠
王盟
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Ganzi State Snail Tibetan Medicine Research And Development Center
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Ganzi State Snail Tibetan Medicine Research And Development Center
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Abstract

The invention provides a kind of pharmaceutical composition for treating numbness disease, skin disease and gynaecological disease, it is the preparation being prepared by the bulk drug of following weight proportion:130 parts of Chinese juniper 60 part, 130 parts of rhododendron anthopogonoide 60 part, 130 parts of Sievers wormwood 60 part, 130 parts of Chinese ephedra 60 part, 130 parts of German tamarisk 60 part, 40 parts of sealwort 20 part, 40 parts of lucid asparagus 20 part, 40 parts of Radix Angelicae Sinensis 20 part, 50 parts of himalayan four-o'clock root 20 part, 50 parts of puncture vine 20 part, 70 parts of amber 30 part, 70 parts of cassia seed 30 part, 70 parts of Semen seu folium abelmoschi moschati 30 part, 50 parts of safflower 20 part, 70 parts of palas word 30 part.Pharmaceutical composition of the present invention, precise and appropriate, sweating is formulated, anti-inflammatory relieves pain, and flat yellow water is promoting blood circulation and removing obstruction in channels.It is rheumatic arthritis, rheumatoid arthritis, gout, hemiplegia, skin disease, women's postpartum disease etc. for numbness disease, potential applicability in clinical practice is good.

Description

A kind of pharmaceutical composition for treating numbness disease, skin disease and gynaecological disease and preparation method thereof And purposes
Technical field
The present invention relates to a kind of pharmaceutical composition for treating numbness disease, skin disease and gynaecological disease and its production and use.
Background technology
Numbness disease refers to the perverse trends such as the positive unsaturated vapor of body, weakened defensive QI, wind, cold, wet, heat and taken advantage of a weak point, and causes qi and blood stagnation, Obstruction of meridians and collaterals, cause the general name of related system disease.《Interior warp》Sayed obstructed visceral pain, six internal organs numbness, extraordinary Fu-organ numbness, five body constituents podomere Numbness, reflect the substance of numbness disease, it is seen that numbness disease has the difference of broad sense and narrow sense, and exceptionally numbness and interior numbness.Numbness person closes.Extensively The numbness disease of justice, refers to the positive unsaturated vapor of body, weakened defensive QI, and perverse trend is taken advantage of a weak point, and zang-fu differentiation qi and blood is for it caused by numbness resistance Disease, including《Interior warp》The network numbness such as the internal organs such as contained lung-energy stagnation syndrome, obstruction of the heart qi numbness and syndrome manifested as myalgia,numbness and flaccidity, muscular rheumatism.The numbness disease of narrow sense, that is, refer to limb therein Body channels and collaterals numbness, pain, numbness are occurred with muscle, muscles and bones, joint, weighed, joint stuffiness, or even it is mainly to face that arthrocele is scorching hot The disease of bed performance.
Skin disease is occurred in skin and the general name of skin accessory organ's disease.Skin is the maximum organ of human body, skin The species of disease is not only various, and the disease that a variety of internal organ occur can also have performance on skin.Cause dermopathic reason a lot, For example skin disease caused by infective agent, such as leprosy, scabies, nosomycosis, bacterial skin infections usually have certain infectiousness, Health is not only influenceed, and is raised fear and social discrimination, but with the improvement of people ' s living standards and science and technology Progressive, the infectious disease such as leprosy has been obviously controlled in the whole world.Other cause dermopathic interior external factor, such as machinery Property, it is physical, chemically, biological, incretion, immunity etc., be increasingly valued by people at present.
The disease of female reproductive system is gynecological disease, including vulva disease, vaginal disease, uterine disease, fallopian tubal Disease, disease of ovary etc..Gynecological disease is women common disease, frequently-occurring disease.But because many people are due to gynecological disease shortage Understanding, lacks the health care to body, various bad life habits etc., make physiological health go from bad to worse in addition, cause some women It is eaten up with illness, and obstinate, bring great inconvenience to normal life, work.
Tibetan medicine is to absorb extensively, merging traditional Chinese medicine and pharmacy, on the basis of Indian Medicinal and big dietitian's pharmacy scheduling theory, The unique medicine systems formed by long-term practice, there is unique curative effect in the treatment of disadvantage, skin disease and gynaecological disease.
The content of the invention
Object of the present invention is to provide the pharmaceutical composition of a kind of new treatment numbness disease, skin disease and gynaecological disease.
A kind of pharmaceutical composition for treating numbness disease, skin disease and gynaecological disease of the present invention, it is by the original of following weight proportion The preparation that material medicine is prepared:60 parts of Chinese juniper, 60 parts of -130 parts of rhododendron anthopogonoides, 60 parts -130 parts of -130 parts of Sievers wormwoods
Preferably, it is the preparation being prepared by the bulk drug of following weight proportion:
Wherein, it by the medicinal powder of bulk drug, the water of bulk drug or extractive with organic solvent is active component that the composition, which is, The preparation being prepared plus pharmaceutically conventional auxiliary material or complementary composition.
Wherein, the preparation is granule, capsule, powder, pill, tablet or vina.
Wherein, the composition is prepared as follows:
(1) bulk drug is taken according to the proportioning of claim 1 or 2, crushes, mix, obtain raw material medicinal powder;
(2) highland barley of the weight of bulk drug 1/3 (w/w) is taken, adds boiling ripe, adds the distiller's yeast of 0.02 times of (w/w) weight of highland barley, Raw material medicinal powder is added, is mixed, sealing, ferments 5 days, produces at 30-50 DEG C.
Present invention also offers the preparation method of foregoing pharmaceutical composition, it is characterised in that:
(1) bulk drug is taken according to foregoing proportioning, crushed, mixed, obtain raw material medicinal powder;
(2) highland barley of the weight of bulk drug 1/3 (w/w) is taken, adds boiling ripe, adds the distiller's yeast of 0.02 times of (w/w) weight of highland barley, Raw material medicinal powder is added, is mixed, sealing, ferments 5 days, produces at 30-50 DEG C.
Present invention also offers foregoing pharmaceutical composition to prepare the drug regimen for the treatment of numbness disease, skin disease or gynaecological disease Purposes in thing.
Wherein, it is described treatment numbness disease pharmaceutical composition be treatment rheumatic arthritis, rheumatoid arthritis, gout or The pharmaceutical composition of person's hemiplegia.
Wherein, the dermopathic medicine for the treatment of is the medicine of dietotherapy psoriasis, dermatitis, eczema or leucoderma.
Wherein, the medicine of the treatment gynaecological disease is treatment gynaecology irregular menstruation, belly distending pain, gynaecology's benign cyst, more The medicine of term.
The monarch compatibility relationship of pharmaceutical composition of the present invention:
1st, monarch drug in a prescription is:60 parts of Chinese juniper, 60 parts of -130 parts of rhododendron anthopogonoides, 60 parts of -130 parts of Sievers wormwoods, 60 part -130 of -130 parts of Chinese ephedras 60 parts -130 parts of German tamarisk of part
2nd, adjutant is:20 parts of sealwort, 20 parts of -40 parts of lucid asparagus, 20 parts of -40 parts of Radix Angelicae Sinensis, 20 parts of -40 parts of himalayan four-o'clock roots - 40 portions of 20 parts -40 parts of puncture vines
3rd, medicine is made:30 parts of amber, 30 parts of -70 parts of cassia seeds, 30 parts of -70 parts of Semen seu folium abelmoschi moschatis -50 parts of palas words of 20 parts of -70 parts of safflowers 30 parts -70 parts.
Pharmaceutical composition of the present invention, precise and appropriate, sweating is formulated, anti-inflammatory relieves pain, and flat yellow water is promoting blood circulation and removing obstruction in channels.It is wind for numbness disease Wet arthritis, rheumatoid arthritis, gout, hemiplegia, skin disease, women's postpartum disease etc., potential applicability in clinical practice is good.
The present invention is described in further details below by embodiment, but is not the limit to the present invention System, according to the above of the present invention, according to the ordinary technical knowledge and customary means of this area, not departing from, the present invention is above-mentioned Under the premise of basic fundamental thought, the modification, replacement or change of other diversified forms can also be made.
Embodiment
Distiller's yeast:Purchased from Angel Yeast Co., Ltd, product standard number:Q/YB2022S, production licence numbering: 420528010005, commodity bar code:6917790980235.
Distiller's yeast is powdery, by distiller's yeast production, company provides.
The preparation of 1 pharmaceutical compositions pharmaceutical compositions of the present invention of embodiment
1st, preparation method
Raw material medicine composition:
In terms of Chinese juniper 60g, the dosage of remaining bulk drug is:Rhododendron anthopogonoide 130g Sievers wormwoods 60g
Preparation technology:
(1) totally 3 kilograms of bulk drug is weighed according to raw material medicine composition, crushed, mixed, obtain raw material medicinal powder;
(2) 1 kilogram of highland barley is taken, adds 5 kg of water, is cooked, adds 20 grams of distiller's yeasts, then adds raw material medicinal powder, is mixed, it is close Envelope, ferment 5 days, produce at 30-50 DEG C.
The preparation of 2 pharmaceutical compositions pharmaceutical compositions of the present invention of embodiment
Raw material medicine composition:
In terms of Chinese juniper 130g, the dosage of remaining bulk drug is:Rhododendron anthopogonoide 60g Sievers wormwoods 130g
Preparation technology:
(1) totally 3 kilograms of bulk drug is weighed according to raw material medicine composition, crushed, mixed, obtain raw material medicinal powder;
(2) 1 kilogram of highland barley is taken, adds 5 kg of water, is cooked, adds 20 grams of distiller's yeasts, then adds raw material medicinal powder, is mixed, it is close Envelope, ferment 5 days, produce at 30-50 DEG C.
The preparation of 3 pharmaceutical compositions pharmaceutical compositions of the present invention of embodiment
Raw material medicine composition:
In terms of Chinese juniper 100g, the dosage of remaining bulk drug is:Rhododendron anthopogonoide 90g Sievers wormwoods 100g
Preparation technology:
(1) totally 3 kilograms of bulk drug is weighed according to raw material medicine composition, crushed, mixed, obtain raw material medicinal powder;
(2) 1 kilogram of highland barley is taken, adds 5 kg of water, is cooked, adds 20 grams of distiller's yeasts, then adds raw material medicinal powder, is mixed, it is close Envelope, ferment 5 days, produce at 30-50 DEG C.
Beneficial effects of the present invention are illustrated below by way of test example.
The effect for the treatment of numbness disease of the present composition of test example 1
1st, experiment material
Present composition group:(present composition prepared by embodiment 3, is please especially examined present composition powder It is whether accurate);
2nd, experimental method
Select arthralgia, that song is stretched is unfavorable, cold causes the people of rheumatoid arthritis patients 100 of pain, is entered using powder Row dipping is treated, and dipping treatment is every time 60 minutes with 80L water, 50 grams of g present composition powders, daily dipping time, is faced Bed 2 time-of-weeks for the treatment of.
Symptom mitigation is determined as effectively.
3rd, experimental result
After carrying out dipping treatment using present composition powder, the illness of 83 patients significantly reduces in 100 patients, Effective percentage is 83%.
Experimental result illustrates that the present composition has the effect for the treatment of rheumatic arthritis.
The present composition of test example 2 treats dermopathic effect
1st, experiment material
With experimental example 1.
Psoriasis, dermatitis, eczema, the people of patients with dermatogic diseases 100 of leucoderma are selected, dipping treatment, medicine are carried out using powder Bath treatment is every time 60 minutes with 80L water, 50g present composition powders, daily dipping time, the time-of-week of clinical treatment 2.
Symptom mitigation is determined as effectively.
3rd, experimental result
After carrying out dipping treatment using present composition powder, the illness of 91 patients significantly reduces in 100 patients, Effective percentage is 91%.
Experimental result illustrates that the present composition, which has, treats dermopathic effect.
The present composition of test example 3 treats the effect of gynaecological disease
1st, experiment material
With experimental example 1.
Gynaecology's irregular menstruation, belly distending pain, gynaecology's benign cyst, the involutional people of gynaecological disease patient 100 are selected, using scattered Agent carries out dipping treatment, and dipping treatment is every time 60 minutes with 80L water, 50g present composition powders, daily dipping time, The time-of-week of clinical treatment 2.
Symptom mitigation is determined as effectively.
3rd, experimental result
After carrying out dipping treatment using present composition powder, the illness of 86 patients significantly reduces in 100 patients, Effective percentage is 86%.
Experimental result illustrates that the present composition has the effect for the treatment of gynaecological disease.
To sum up, the formula of pharmaceutical composition of the present invention is precise and appropriate, has the numbness such as treatment rheumatic arthritis disease, skin disease and woman The effect of section's disease, potential applicability in clinical practice is good.

Claims (10)

  1. A kind of 1. pharmaceutical composition for treating numbness disease, skin disease and gynaecological disease, it is characterised in that:It is by following weight proportion The preparation that bulk drug is prepared:
  2. 2. pharmaceutical composition according to claim 1, it is characterised in that:It is the bulk drug preparation by following weight proportion The preparation formed:
  3. 3. pharmaceutical composition according to claim 1 or 2, it is characterised in that:It is medicinal powder, the bulk drug by bulk drug Water or extractive with organic solvent are active component, the preparation being prepared plus pharmaceutically conventional auxiliary material or complementary composition.
  4. 4. pharmaceutical composition according to claim 3, it is characterised in that:The preparation be granule, capsule, powder, Pill, tablet or vina.
  5. 5. according to the pharmaceutical composition described in Claims 1 to 4 any one, it is characterised in that:It is prepared as follows:
    (1) bulk drug is taken according to the proportioning of claim 1 or 2, crushes, mix, obtain raw material medicinal powder;
    (2) highland barley of the weight of bulk drug 1/3 (w/w) is taken, adds boiling ripe, adds the distiller's yeast of 0.02 times of (w/w) weight of highland barley, is added Raw material medicinal powder, mix, sealing, ferment 5 days, produce at 30-50 DEG C.
  6. 6. the preparation method of claim 1-5 any one described pharmaceutical compositions, it is characterised in that:
    (1) bulk drug is taken according to the proportioning of claim 1 or 2, crushes, mix, obtain raw material medicinal powder;
    (2) highland barley of the weight of bulk drug 1/3 (w/w) is taken, adds boiling ripe, adds the distiller's yeast of 0.02 times of (w/w) weight of highland barley, is added Raw material medicinal powder, mix, sealing, ferment 5 days, produce at 30-50 DEG C.
  7. 7. claim 1-5 any one described pharmaceutical composition is preparing the medicine for the treatment of numbness disease, skin disease or gynaecological disease Purposes in composition.
  8. 8. purposes according to claim 7, it is characterised in that:The pharmaceutical composition of the treatment numbness disease is treatment rheumatic Arthritis, rheumatoid arthritis, the pharmaceutical composition of gout or hemiplegia.
  9. 9. purposes according to claim 7, it is characterised in that:The dermopathic medicine for the treatment of is dietotherapy psoriasis, skin The medicine of scorching, eczema or leucoderma.
  10. 10. purposes according to claim 7, it is characterised in that:The medicine of the treatment gynaecological disease is the menstruation for the treatment of gynaecology Uncomfortable, belly distending pain, gynaecology's benign cyst, involutional medicine.
CN201610515026.9A 2016-06-29 2016-06-29 A kind of pharmaceutical composition for treating numbness disease, skin disease and gynaecological disease and its production and use Pending CN107536950A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108926691A (en) * 2018-09-03 2018-12-04 达瓦 Liquid medicine and the preparation method and application thereof
CN109432298A (en) * 2018-12-26 2019-03-08 阜新蒙古族自治县蒙医医院 A kind of anaesthetic for the treatment of of arthritis and preparation method thereof
CN110302311A (en) * 2019-08-21 2019-10-08 西藏宇拓健康品有限公司 A kind of Tibetan medicine's dipping and its preparation process and application
CN110934995A (en) * 2019-12-17 2020-03-31 普化才让 Chinese herbal medicine foot bath powder
CN114366799A (en) * 2022-01-19 2022-04-19 青海卫生职业技术学院 Plateau manna medicated bath preparation and preparation process thereof

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CN1660051A (en) * 2005-01-21 2005-08-31 西藏宇妥藏药研究有限公司 Method for preparing bath powder of Tibet medicine and its quality control method
CN1813861A (en) * 2005-11-29 2006-08-09 久美彭措 Five-ingredient medicinal-bathing particle
JP5527951B2 (en) * 2007-12-17 2014-06-25 花王株式会社 External preparation, hair restorer, NFAT signal inhibitor and calcineurin inhibitor
CN104547988A (en) * 2014-12-10 2015-04-29 天祝藏族自治县藏医院 Tibetan medicine medicated bath for treating psoriasis and use method thereof

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108926691A (en) * 2018-09-03 2018-12-04 达瓦 Liquid medicine and the preparation method and application thereof
CN109432298A (en) * 2018-12-26 2019-03-08 阜新蒙古族自治县蒙医医院 A kind of anaesthetic for the treatment of of arthritis and preparation method thereof
CN110302311A (en) * 2019-08-21 2019-10-08 西藏宇拓健康品有限公司 A kind of Tibetan medicine's dipping and its preparation process and application
CN110934995A (en) * 2019-12-17 2020-03-31 普化才让 Chinese herbal medicine foot bath powder
CN114366799A (en) * 2022-01-19 2022-04-19 青海卫生职业技术学院 Plateau manna medicated bath preparation and preparation process thereof

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