CN107519540A - A kind of implantable fibroin/bacteria cellulose/graphene composite conductive film of high tensile flexible printing opacity - Google Patents
A kind of implantable fibroin/bacteria cellulose/graphene composite conductive film of high tensile flexible printing opacity Download PDFInfo
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- CN107519540A CN107519540A CN201710550750.XA CN201710550750A CN107519540A CN 107519540 A CN107519540 A CN 107519540A CN 201710550750 A CN201710550750 A CN 201710550750A CN 107519540 A CN107519540 A CN 107519540A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L31/125—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L31/126—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing carbon fillers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
Abstract
The present invention provides a kind of high tensile flexible printing opacity implantable fibroin/bacteria cellulose/graphene composite conductive film, including micro/nano level coconut palm fruit bacteria cellulose, fibroin, graphene and electrode, specific preparation method are：Coconut palm fruit bacteria cellulose is smashed to form micro/nano level bacterial cellulose solution, is well mixed to form composite solution with the fibroin aqueous solution, then graphene aqueous solution is added dropwise, vacuum filter removes solvent, the composite solution concentrated；Then Ti/Au electrodes, the composite solution of concentration, polycarbonate membrane are placed in PE substrates successively, spontaneously dried using laminating to solidification, PE substrates and polycarbonate membrane are removed, obtains the implantable fibroin/bacteria cellulose/graphene composite conductive film of high tensile flexible printing opacity.Preparation method of the present invention is simple, is well mixed between raw material, and the thin film strength of preparation is high, and flexible, transparency is good, good biocompatibility, also conductive energy, meets the requirement of implantable medical material.
Description
Technical field
The invention belongs to textile material technical field, and in particular to and a kind of implantable fibroin of high tensile flexible printing opacity/
Bacteria cellulose/graphene composite conductive film.
Background technology
Fibroin is a kind of natural polymer fibrin extracted from silk, is made up of 18 kinds of a-amino acids, tool
There are biocompatibility, degradability, nontoxicity, a certain degree of fragility and have oxygen permeability under hygrometric state, fibroin can be with
Staple fibre, film, non-woven fabrics, porous support, hydrogel, micro- is formed separately as raw material or with other raw material combination preparations
The materials such as nano-particle.Bacteria cellulose is that the porous mesh nano level boiomacromolecule synthesized by microbial fermentation polymerize
Thing, by D- glucopyranoses, with β -1-4 glycosidic bonds, linearly link forms, and is compared with plant cellulose, bacterial fibers have superfinishing
Thin nanoscale network structure, high chemical purity, high-crystallinity, high polymerization degree, high-tensile and modulus of elasticity, splendid is anti-
Tearing ability and shape maintain ability, high moisture holding capacity, are widely used in field of food.Containing a large amount of in bacteria cellulose
Hydroxyl, therefore bacteria cellulose can be compounded to form various functions composite with fibroin.
A kind of fibroin/bacteria cellulose composite aquogel and its preparation disclosed in Chinese patent CN 106492286A
Methods and applications, by the bacteria cellulose aquagel being modified through glycidyl trimethylammonium chloride surface and fibroin and bone shape
State occurs albumen -2 and is used as raw material, prepares to form compound hydrogel material through electric gel technique, fibroin is in bacteria cellulose
Network structure is formed in hydrogel, forms dual network hole support, is more beneficial for the apposition growth of bone morphogenesis protein-2.In
Disclosed composites prepared for artificial small-caliber vascular of state patent CN 105031736A and preparation method thereof, by bacterium
Cellulose membrane is placed in fibroin solutions after carboxylated is handled, and crosslinking is compounded to form composite.By above-mentioned prior art
Understand, the research for the composite at present preparing bacteria cellulose as raw material with fibroin is actually rare, because bacterium
Cellulose there is the problem of yield is relatively low and production cost is higher, and bacteria cellulose addition manner it is more with hydrogel or
The form of person's film is combined with fibroin material, increases mixing and the crosslinking difficulty of bacteria cellulose and fibroin,
Influence the overall performance of composite.
Coconut palm fruit is a kind of gelatinous hy-drophilic polysaccharide material, is using coconut milk as primary raw material, through acetobacter culture
Fermentation and a kind of manufactured colloid bacteria cellulose, raw material sources are extensive, cost is cheap, and coconut palm fruit bacteria cellulose has purity
The properties such as height, crystallinity are high, water absorbing force is strong, tensile strength is good, and it is not soluble in water, it is not easy to be polluted by other polysaccharose substances, has
There is very high retention ability, have combination and exchange capacity to cation, have suction-operated to organic matter.The present invention is by micro/nano level coconut palm
With fibroin and graphene, as primary raw material, high tensile flexible is prepared by vacuum filter and laminating in fruit bacterial fibers
The implantable composite conductive film of printing opacity.
The content of the invention
The technical problem to be solved in the present invention is to provide fibroin/bacterial fibers that a kind of high tensile flexible printing opacity is implantable
Element/graphene composite conductive film, using micro/nano level coconut palm fruit bacterial fibers and fibroin and graphene as primary raw material, three
After well mixed, fibroin/bacteria cellulose/graphene composite film, this hair is prepared by vacuum filter and laminating
Bright preparation method is simple, is well mixed between raw material, and the thin film strength of preparation is high, and flexible, optical transparency is good, biocompatibility
It is good, also with certain electric conductivity, meet the requirement of implantable medical material.
In order to solve the above technical problems, the technical scheme is that：
A kind of implantable fibroin/bacteria cellulose/graphene composite conductive film of high tensile flexible printing opacity, the silk
Albumen/bacteria cellulose/graphene composite conductive film includes coconut palm fruit bacteria cellulose, fibroin, graphene and Ti/Au electricity
Pole, the coconut palm fruit bacteria cellulose are micro/nano level coconut palm fruit bacteria cellulose.
As the preferred of above-mentioned technical proposal, the fibroin/bacteria cellulose/graphene composite conductive film is silk
Albumen/bacteria cellulose/graphene composite solution is prepared through polycarbonate filter film vacuum filter and laminating.
As the preferred of above-mentioned technical proposal, preparation method comprises the following steps：
(1) coconut palm fruit bacteria cellulose is added in deionized water, is transferred to juice extractor, smash to form micro/nano level bacterium fibre
Plain solution is tieed up, by silk cocoon through sodium bicarbonate solution degumming, the dissolving of calcium chloride ternary solution, it is water-soluble that fibroin is made in 3 days in dialysis
Liquid, micro/nano level bacterial cellulose solution is well mixed with fibroin solutions to form fibroin/bacteria cellulose compound
Solution；
(2) graphene aqueous solution, side drop are added dropwise in the fibroin/bacteria cellulose composite solution for preparing step (1)
Edged stirs, and fibroin/bacteria cellulose/graphene composite solution is obtained, under vacuum, through makrolon membrane filtration
Remove solvent, the composite solution concentrated；
(3) composite solution, the polycarbonate membrane for the concentration for successively preparing Ti/Au electrodes, step (2) are placed in PE substrates
On, opposite pressure is applied to PE substrates and polycarbonate membrane respectively using laminating, spontaneously dries to solidifying, removes PE substrates
And polycarbonate membrane, obtain the implantable fibroin/bacteria cellulose/graphene composite conductive film of high tensile flexible printing opacity.
As the preferred of above-mentioned technical proposal, in the step (1), bacterial fibers in micro/nano level bacterial cellulose solution
The a diameter of 60-100nm, length 0.8-8um of element.
As the preferred of above-mentioned technical proposal, in the step (1), the quality of fibroin point in the fibroin aqueous solution
Number is 7-10%.
As the preferred of above-mentioned technical proposal, in the step (1), silkworm in fibroin/bacteria cellulose composite solution
The mass ratio of silk-fibroin and bacteria cellulose is 3-5.5:1.
As the preferred of above-mentioned technical proposal, in the step (2), fibroin/bacteria cellulose/graphene is compound molten
The mass fraction of graphene is not higher than 20% in liquid.
As the preferred of above-mentioned technical proposal, in the step (2), the vacuum of vacuum condition is 0.01-0.1MPa.
As the preferred of above-mentioned technical proposal, in the step (2), the solid content in the composite solution of concentration is 50-
70%.
As the preferred of above-mentioned technical proposal, in the step (3), the pressure for applying opposite pressure is 5-7MPa, is applied
The time for adding opposite pressure is 5-15min.
Compared with prior art, the invention has the advantages that：
(1) the implantable fibroin/bacteria cellulose/graphene composite conductive of the high tensile flexible printing opacity for preparing of the present invention
Film includes micro/nano level coconut palm fruit bacteria cellulose, random by 100 angstroms of microfiber bundle in micro/nano level coconut palm fruit bacteria cellulose
Orientation combines, and micro/nano level coconut palm fruit bacteria cellulose forms Weak Gels system with Free water, then coconut palm fruit bacteria cellulose
Natural biology is derived from itself with fibroin, and the compatibility of bacteria cellulose and fibroin is good, and bacterial fibers can be achieved
Element mixes with the uniform of fibroin, realizes homogeneous mixed gel system, and graphene aqueous solution, side are finally slowly added dropwise again
Side stirring is added dropwise, dispersed graphite alkene material, and Bacterial cellulose microfibrils beam has absorption property to greatest extent is adsorbable
There is agglomeration, realize micro/nano level coconut palm fruit bacteria cellulose, fibroin and graphene in fixed graphene, placing graphite alkene
It is evenly distributed in system, improves the problem that is uniformly dispersed between raw material, be advantageously implemented the homogeneous of thin-film material performance
Property.
(2) the implantable fibroin/bacteria cellulose/graphene composite conductive of the high tensile flexible printing opacity for preparing of the present invention
Film includes micro/nano level coconut palm fruit bacteria cellulose, fibroin and graphene, wherein micro/nano level coconut palm fruit bacteria cellulose and
Fibroin is primary raw material, and both form double-layer network pore space structure in the film, makes the thin-film material of preparation with very high
Tensile strength, Young's modulus and elasticity, mechanical performance is excellent, and micro/nano level coconut palm fruit bacteria cellulose and fibroin obtain
Photosensitiveness is good, and the light transmittance for the thin-film material that both are mixed with adds a small amount of grapheme material, kept afterwards up to 90%
In the case that the light transmittance of thin-film material is not less than 85%, thin-film material electric conductivity is assigned.In addition, coconut palm fruit bacteria cellulose and
Fibroin derives from natural biology in itself, and they are stronger with the compatibility of cell, and the life in approximation can be provided for cell
The extracellular matrix support condition of long development, can make the cell aggregation structure of organization of regulation control, good biocompatibility, be into tissue
Implantable medical material provides may.
(3) it is well mixed between fibroin, bacteria cellulose and graphene prepared by the present invention and forms mixed system, then is adopted
Being filtered off with polycarbonate membrane and remove solvent, spontaneously dried to solidification and obtained using laminating, preparation method is simple, and controllability is good,
Fibroin/bacteria cellulose of preparation/graphene composite conductive film strength is high, and flexible, optical transparency is good, bio-compatible
Property is good, also with certain electric conductivity, meets the requirement of implantable medical material.
Brief description of the drawings
Accompanying drawing described herein is used for providing a further understanding of the present invention, forms the part of the application, not
Inappropriate limitation of the present invention is formed, in the accompanying drawings：
Accompanying drawing 1 is coconut palm fruit bacterial cellulose solution figure；
Accompanying drawing 2 is fibroin solutions preparation process schematic diagram；
Accompanying drawing 3 is fibroin/bacteria cellulose composite solution figure；
Accompanying drawing 4 is fibroin/bacteria cellulose/graphene composite solution figure；
Accompanying drawing 5 is that fibroin/bacterial cellulose solution filtering prepares schematic diagram；
Accompanying drawing 6 is that fibroin/bacteria cellulose/graphene solution laminating prepares schematic diagram；
Accompanying drawing 7 is fibroin/bacteria cellulose/graphene composite and flexible conducting film figure；
Accompanying drawing 8 is the transmission electron microscope picture of fibroin/bacteria cellulose/graphene composite and flexible conducting film；
Accompanying drawing 9 is the light transmission figure of thin-film material；
Accompanying drawing 10 is the 3T3 cell culture figures of thin-film material.
Wherein, 1, micro/nano level coconut palm fruit bacteria cellulose 2, fibroin 3, polycarbonate membrane 4, Ti/Au electrodes 5,
PE substrates.
Embodiment
The present invention is described in detail below in conjunction with specific embodiment, herein illustrative examples and explanation of the invention
For explaining the present invention, but it is not as a limitation of the invention.
Embodiment 1：
(1) coconut palm fruit bacteria cellulose is added in deionized water, is transferred to juice extractor, smashes to form a diameter of 60-
100nm, length is 0.8-8um micro/nano level bacterial cellulose solution, by sodium bicarbonate solution degumming of the silk cocoon through 0.5wt%
45min, after washing drying, calcium chloride ternary solution dissolving 2h is placed at 60 DEG C, is dialysed 3 days with deionized water and 7wt% is made
The fibroin aqueous solution, micro/nano level bacterial cellulose solution is well mixed with fibroin solutions to form fibroin/thin
Fungin composite solution.
(2) graphene aqueous solution will be added dropwise in fibroin/bacteria cellulose composite solution, stirs, obtain when being added dropwise
Fibroin/bacteria cellulose/graphene composite solution, in the case where vacuum is 0.01MPa vacuum condition, through polycarbonate membrane
Filter off and remove solvent, obtain the composite solution for the concentration that solid content is 50%.
(3) Ti/Au electrodes, the composite solution of concentration, polycarbonate membrane are placed in PE substrates successively, using laminating point
It is other to apply the opposite pressure 5min that pressure is 5MPa to PE substrates and polycarbonate membrane, spontaneously dry to solidifying, remove PE bases
Bottom and polycarbonate membrane, obtain the implantable fibroin/bacteria cellulose/graphene composite conductive film of high tensile flexible printing opacity.
Embodiment 2：
(1) coconut palm fruit bacteria cellulose is added in deionized water, is transferred to juice extractor, smashes to form a diameter of 60-
100nm, length is 0.8-8um micro/nano level bacterial cellulose solution, by sodium bicarbonate solution degumming of the silk cocoon through 0.5wt%
45min, after washing drying, calcium chloride ternary solution dissolving 3h is placed at 70 DEG C, is dialysed 3 days with deionized water and 10wt% is made
The fibroin aqueous solution, micro/nano level bacterial cellulose solution is well mixed with fibroin solutions to form fibroin/thin
Fungin composite solution.
(2) graphene aqueous solution will be added dropwise in fibroin/bacteria cellulose composite solution, stirs, obtain when being added dropwise
Fibroin/bacteria cellulose/graphene composite solution, in the case where vacuum is 0.1MPa vacuum condition, through polycarbonate membrane
Filter off and remove solvent, obtain the composite solution for the concentration that solid content is 70%.
(3) Ti/Au electrodes, the composite solution of concentration, polycarbonate membrane are placed in PE substrates successively, using laminating point
It is other to apply the opposite pressure 15min that pressure is 7MPa to PE substrates and polycarbonate membrane, spontaneously dry to solidifying, remove PE bases
Bottom and polycarbonate membrane, obtain the implantable fibroin/bacteria cellulose/graphene composite conductive film of high tensile flexible printing opacity.
Embodiment 3：
(1) coconut palm fruit bacteria cellulose is added in deionized water, is transferred to juice extractor, smashes to form a diameter of 60-
100nm, length is 0.8-8um micro/nano level bacterial cellulose solution, by sodium bicarbonate solution degumming of the silk cocoon through 0.5wt%
45min, after washing drying, calcium chloride ternary solution dissolving 2.5h is placed at 65 DEG C, is dialysed 3 days and is made with deionized water
The 8wt% fibroin aqueous solution, micro/nano level bacterial cellulose solution is well mixed to form silk egg with fibroin solutions
In vain/bacteria cellulose composite solution.
(2) graphene aqueous solution will be added dropwise in fibroin/bacteria cellulose composite solution, stirs, obtain when being added dropwise
Fibroin/bacteria cellulose/graphene composite solution, in the case where vacuum is 0.05MPa vacuum condition, through polycarbonate membrane
Filter off and remove solvent, obtain the composite solution for the concentration that solid content is 60%.
(3) Ti/Au electrodes, the composite solution of concentration, polycarbonate membrane are placed in PE substrates successively, using laminating point
It is other to apply the opposite pressure 10min that pressure is 6MPa to PE substrates and polycarbonate membrane, spontaneously dry to solidifying, remove PE bases
Bottom and polycarbonate membrane, obtain the implantable fibroin/bacteria cellulose/graphene composite conductive film of high tensile flexible printing opacity.
Embodiment 4：
(1) coconut palm fruit bacteria cellulose is added in deionized water, is transferred to juice extractor, smashes to form a diameter of 60-
100nm, length is 0.8-8um micro/nano level bacterial cellulose solution, by sodium bicarbonate solution degumming of the silk cocoon through 0.5wt%
45min, after washing drying, calcium chloride ternary solution dissolving 2h is placed at 70 DEG C, is dialysed 3 days with deionized water and 9wt% is made
The fibroin aqueous solution, micro/nano level bacterial cellulose solution is well mixed with fibroin solutions to form fibroin/thin
Fungin composite solution.
(2) graphene aqueous solution will be added dropwise in fibroin/bacteria cellulose composite solution, stirs, obtain when being added dropwise
Fibroin/bacteria cellulose/graphene composite solution, in the case where vacuum is 0.03MPa vacuum condition, through polycarbonate membrane
Filter off and remove solvent, obtain the composite solution for the concentration that solid content is 55%.
(3) Ti/Au electrodes, the composite solution of concentration, polycarbonate membrane are placed in PE substrates successively, using laminating point
It is other to apply the opposite pressure 9min that pressure is 5.5MPa to PE substrates and polycarbonate membrane, spontaneously dry to solidifying, remove PE
Substrate and polycarbonate membrane, obtain the implantable fibroin/bacteria cellulose/graphene composite conductive of high tensile flexible printing opacity
Film.
Embodiment 5：
(1) coconut palm fruit bacteria cellulose is added in deionized water, is transferred to juice extractor, smashes to form a diameter of 60-
100nm, length is 0.8-8um micro/nano level bacterial cellulose solution, by sodium bicarbonate solution degumming of the silk cocoon through 0.5wt%
45min, after washing drying, calcium chloride ternary solution dissolving 3h is placed at 60 DEG C, is dialysed 3 days with deionized water and 8wt% is made
The fibroin aqueous solution, micro/nano level bacterial cellulose solution is well mixed with fibroin solutions to form fibroin/thin
Fungin composite solution.
(2) graphene aqueous solution will be added dropwise in fibroin/bacteria cellulose composite solution, stirs, obtain when being added dropwise
Fibroin/bacteria cellulose/graphene composite solution, in the case where vacuum is 0.1MPa vacuum condition, through polycarbonate membrane
Filter off and remove solvent, obtain the composite solution for the concentration that solid content is 65%.
(3) Ti/Au electrodes, the composite solution of concentration, polycarbonate membrane are placed in PE substrates successively, using laminating point
It is other to apply the opposite pressure 10min that pressure is 7MPa to PE substrates and polycarbonate membrane, spontaneously dry to solidifying, remove PE bases
Bottom and polycarbonate membrane, obtain the implantable fibroin/bacteria cellulose/graphene composite conductive film of high tensile flexible printing opacity.
After testing, the implantable fibroin/bacteria cellulose/graphene of the high tensile flexible printing opacity of embodiment 1-5 preparations
The result of the fibroin/bacteria cellulose film and fibroin film of composite conductive film and prior art is as follows：
As seen from the above table, the implantable fibroin/bacteria cellulose/graphene of the high tensile flexible printing opacity for preparing of the present invention
The mechanical property of composite conductive film is much better than pure regenerated silk fibroin membrane, and in the case where adding a small amount of graphene, mechanical property
It can influence less, electric conductivity significantly improves.
And from accompanying drawing result it was found from, the implantable fibroin/bacteria cellulose/graphene of high tensile flexible printing opacity is multiple
Close each component in conducting film to be well mixed, adding a small amount of graphene influences less optical transmittance property, and graphene content is higher
The transmissivity of optical thin film is smaller.In addition, it is fibroin/bacterium that the left side of accompanying drawing 10, which is bacteria cellulose/graphene film the right,
Cellulose/graphene film is the cytological map of 3T3 cell culture 3 days, illustrates that conducting film prepared by the present invention has good biology
Compatibility.
The above-described embodiments merely illustrate the principles and effects of the present invention, not for the limitation present invention.It is any ripe
Know the personage of this technology all can carry out modifications and changes under the spirit and scope without prejudice to the present invention to above-described embodiment.Cause
This, those of ordinary skill in the art is complete without departing from disclosed spirit and institute under technological thought such as
Into all equivalent modifications or change, should by the present invention claim be covered.
Claims (10)
1. a kind of implantable fibroin/bacteria cellulose/graphene composite conductive film of high tensile flexible printing opacity, its feature exist
In：Fibroin/bacteria cellulose/graphene composite conductive the film includes coconut palm fruit bacteria cellulose, fibroin, graphene
With Ti/Au electrodes, the coconut palm fruit bacteria cellulose is micro/nano level coconut palm fruit bacteria cellulose.
2. a kind of implantable fibroin/bacteria cellulose/graphene of high tensile flexible printing opacity according to claim 1 is multiple
Close conducting film, it is characterised in that：Fibroin/bacteria cellulose/graphene composite conductive the film is that fibroin/bacterium is fine
Dimension element/graphene composite solution is prepared through polycarbonate filter film vacuum filter and laminating.
3. a kind of implantable fibroin/bacteria cellulose/graphene of high tensile flexible printing opacity according to claim 1 is multiple
Close conducting film, it is characterised in that preparation method comprises the following steps：
(1) coconut palm fruit bacteria cellulose is added in deionized water, is transferred to juice extractor, smashes to form micro/nano level bacteria cellulose
Solution, through sodium bicarbonate solution degumming, the dissolving of calcium chloride ternary solution, dialysis the fibroin aqueous solution is made in 3 days in silk cocoon, will
Micro/nano level bacterial cellulose solution is well mixed to form fibroin/bacteria cellulose composite solution with fibroin solutions；
(2) graphene aqueous solution is added dropwise in the fibroin/bacteria cellulose composite solution for preparing step (1), when being added dropwise
Stirring, obtains fibroin/bacteria cellulose/graphene composite solution, under vacuum, filters off and remove through polycarbonate membrane
Solvent, the composite solution concentrated；
(3) composite solution, the polycarbonate membrane for the concentration for successively preparing Ti/Au electrodes, step (2) are placed in PE substrates, are adopted
Apply opposite pressure to PE substrates and polycarbonate membrane respectively with laminating, natural drying removes PE substrates and gathered to solidifying
Carbonic ester film, obtain the implantable fibroin/bacteria cellulose/graphene composite conductive film of high tensile flexible printing opacity.
4. a kind of implantable fibroin/bacteria cellulose/graphene of high tensile flexible printing opacity according to claim 3 is multiple
Close conducting film, it is characterised in that：In the step (1), bacteria cellulose is a diameter of in micro/nano level bacterial cellulose solution
60-100nm, length 0.8-8um.
5. a kind of implantable fibroin/bacteria cellulose/graphene of high tensile flexible printing opacity according to claim 3 is multiple
Close conducting film, it is characterised in that：In the step (1), the mass fraction of fibroin is 7-10% in the fibroin aqueous solution.
6. a kind of implantable fibroin/bacteria cellulose/graphene of high tensile flexible printing opacity according to claim 3 is multiple
Close conducting film, it is characterised in that：In the step (1), fibroin and bacterium in fibroin/bacteria cellulose composite solution
The mass ratio of cellulose is 3-5.5:1.
7. a kind of implantable fibroin/bacteria cellulose/graphene of high tensile flexible printing opacity according to claim 3 is multiple
Close conducting film, it is characterised in that：In the step (2), graphene in fibroin/bacteria cellulose/graphene composite solution
Mass fraction be not higher than 20%.
8. a kind of implantable fibroin/bacteria cellulose/graphene of high tensile flexible printing opacity according to claim 3 is multiple
Close conducting film, it is characterised in that：In the step (2), the vacuum of vacuum condition is 0.01-0.1MPa.
9. a kind of implantable fibroin/bacteria cellulose/graphene of high tensile flexible printing opacity according to claim 3 is multiple
Close conducting film, it is characterised in that：In the step (2), the solid content in the composite solution of concentration is 50-70%.
A kind of 10. implantable fibroin/bacteria cellulose/graphene of high tensile flexible printing opacity according to claim 3
Composite conductive film, it is characterised in that：In the step (3), the pressure for applying opposite pressure is 5-7MPa, applies opposite pressure
The time of power is 5-15min.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108503804A (en) * | 2018-04-27 | 2018-09-07 | 济南圣泉集团股份有限公司 | A kind of method of grapheme material modified poly ester master batch and grapheme material modified poly ester master batch therefrom and application |
| CN109880382A (en) * | 2019-01-31 | 2019-06-14 | 南通纺织丝绸产业技术研究院 | A kind of fibroin/graphene composite conductive film and preparation method thereof |
| CN111893765A (en) * | 2019-05-06 | 2020-11-06 | 上海翔雍新材料科技有限公司 | Cellulose/fibroin composite aerogel long fiber and preparation method thereof |
| CN114864137A (en) * | 2022-05-08 | 2022-08-05 | 西北工业大学 | Super-soft skin-smoothing brain electrode based on bacterial cellulose substrate and preparation method |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102737786A (en) * | 2012-06-28 | 2012-10-17 | 北京理工大学 | Preparation method of cellulose nanofiber-based flexible transparent conductive membrane |
| CN104674362A (en) * | 2015-03-11 | 2015-06-03 | 湖州吉昌丝绸有限公司 | Preparation method of fibroin/graphene conductive fiber |
| CN104927090A (en) * | 2014-11-18 | 2015-09-23 | 青岛科技大学 | Flexible transparent conductive composite membrane made from graphene and cellulose, and preparation method therefor |
-
2017
- 2017-07-07 CN CN201710550750.XA patent/CN107519540B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102737786A (en) * | 2012-06-28 | 2012-10-17 | 北京理工大学 | Preparation method of cellulose nanofiber-based flexible transparent conductive membrane |
| CN104927090A (en) * | 2014-11-18 | 2015-09-23 | 青岛科技大学 | Flexible transparent conductive composite membrane made from graphene and cellulose, and preparation method therefor |
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