CN107519294A - A kind of capsule for treating knee osteoarthritis - Google Patents

A kind of capsule for treating knee osteoarthritis Download PDF

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Publication number
CN107519294A
CN107519294A CN201610489215.3A CN201610489215A CN107519294A CN 107519294 A CN107519294 A CN 107519294A CN 201610489215 A CN201610489215 A CN 201610489215A CN 107519294 A CN107519294 A CN 107519294A
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Prior art keywords
parts
capsule
root
knee osteoarthritis
radix
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CN201610489215.3A
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Chinese (zh)
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陈冠卿
王芳
陈洪波
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/27Asclepiadaceae (Milkweed family), e.g. hoya
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716Clematis (leather flower)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

A kind of capsule for treating knee osteoarthritis, belongs to technical field of traditional Chinese medicine preparation.It is mainly made up of 10 kinds of bulk drugs such as bark of ash, prepared rhizome of rehmannia, the root of herbaceous peony, Radix Angelicae Sinensis, the root of Chinese clematis, pawpaw, Radix Astragali, and it is standby that capsule is made.The present invention has Yishen Jianpi, and expelling wind and clearing away cold, promoting blood circulation dehumidifying, the function of removing obstruction in channels to relieve pain, treatment knee osteoarthritis effect is good, convenient to take, safely and effectively.

Description

A kind of capsule for treating knee osteoarthritis
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation.
Background technology
Knee osteoarthritis are a kind of common diseases, and frequently-occurring disease is common in mid-aged population, the trouble of the patient more than 60 years old Sick rate is 50%, and the crowd of more than 75 years old has then reached 80%.Gonalgia and tenderness, swelling, or interior have a large amount of cunnings Liquid;Knee stiffness, moving obstacle can with leg muscle atrophy, when serious, joint may occur in which turns up or Varus deformity.It is existing Special effective treatment method is there is no for treatment of the medical science at present to this disease.
The content of the invention
The purpose of the present invention is overcome the deficiencies in the prior art, there is provided a kind of capsule for treating knee osteoarthritis.It has Yishen Jianpi, expelling wind and clearing away cold, promoting blood circulation dehumidifying, the function of removing obstruction in channels to relieve pain.It is good to treat knee osteoarthritis effect.It can reach and take Facilitate, safely and effectively purpose.
The technical solution adopted for the present invention to solve the technical problems is by bark of ash, prepared rhizome of rehmannia, the root of herbaceous peony, Radix Angelicae Sinensis, Wheeling 10 kinds of celestial being, paniculate swallowwort, radix cyathulae, levisticum, pawpaw, Radix Astragali bulk drugs are formed.
About drug ingedient major function and preparation in invention formulation.
Bark of ash in the present invention, it is bitter in taste, pungent, put down.The first, second of alkaloid containing bark of ash, third, volatile oil etc..Scattered wind is dispelled It is wet, activate blood and relax tendons.Arthralgia pain due to rheumatism is cured mainly, muscles and bones contraction, jaundice, is had blood in stool, osteopyrexia and fever.
Prepared rhizome of rehmannia in the present invention, nature and flavor are sweet, slight bitter, are slightly cold.Containing mannitol, glucose, alkaloid, aliphatic acid, Rehmanin, Catalpol etc..Enriching yin and nourishing kidney, tonifying blood and regulating menstruation.It is few to cure mainly deficiency of Yin blood, essence, which is lost, strains, and the soreness of waist is dizzy, deaf, menstruation It is uncomfortable, uterine bleeding, poliosis.
The root of herbaceous peony in the present invention, nature and flavor acid is bitter, is slightly cold.Containing volatile oil, benzoic acid, tannin, mucilaginous substance, Paeoniflorin Deng.The moon is held back in soft liver analgesic, blood-nourishing.Stomachache rush down dysentery is cured mainly, waist rib stomachache, four limbs contraction is anxious, irregular menstruation, under uterine bleeding band.
Radix Angelicae Sinensis in the present invention, nature and flavor sweet, acrid, warm.Containing volatile oil, palmitic acid, sucrose, nicotinic acid, vitamin E Deng.Replenishing and activating blood, blood stasis dispersing and fresh blood promoting, menstruation regulating are moisturized.Cure mainly deficiency of blood headache, Low Back Pain, all pains of trusted subordinate, dry feces, Impotence numbness, Abdominal mass, ulcer Sore ulcers, Amenorrhea, menalgia, uterine bleeding.
The root of Chinese clematis in the present invention, nature and flavor are pungent, salty, temperature.Alcohol containing the Chinese bulbul, anemonin, sterol, carbohydrate and saponin Deng.Wind-damp dispelling, analgesic, change fish-bone.Arthralgia pain due to rheumatism, waist and knee and limbs pain are cured mainly, a lump in the abdomen causing distension and pain.
Paniculate swallowwort in the present invention, nature and flavor are pungent, temperature.Containing Paeonol etc..Removing toxicity for detumescence, dispelling wind and removing obstruction in the meridians, calm diuresis, only Dysentery, the promoting flow of qi and blood circulation, analgesic.Mainly curing rheumatism, traumatic injury, dysentery, turgor of having a stomachache, toothache, hepatic sclerosis, ascites etc..
Radix cyathulae in the present invention, nature and flavor are sweet, slight bitter, put down.Containing sterols.Expelling wind and removing dampness, restore menstrual flow and invigorate blood circulation.Cure mainly waist Knee pain, Amenorrhea, abdominal mass, blood strangury.
Levisticum in the present invention, nature and flavor are pungent, temperature.Containing volatile oil.Expelling wind and eliminating dampness, eliminating cold to stop pain.Cure mainly arthralgia pain due to rheumatism, Soreness of waist and knee joint, numb limb.
Pawpaw in the present invention, nature and flavor acid, temperature.Containing saponin, glycosides displayed, papain, organic acid etc..Soothing the liver and Stomach, clearing damp relaxing muscles and tendons.Cure mainly choleraic myospasm, warm numbness tinea pedis, oedema, dysentery.
The Radix Astragali in the present invention, nature and flavor are sweet, tepor.Containing choline, glycine betaine, folic acid, amino acid, carbohydrate etc..Tonifying Qi Gu table, promoting pus discharge and tissue regeneration.Exterior deficiency spontaneous perspiration, night sweat are cured mainly, deficiency of vital energy blood is taken off, splenasthenic diarrhea, and ulcer, which is not burst or burst, not to be restrained, and one Cut the disease of insufficiency of primordial QI.
The etiology and pathogenesis of knee osteoarthritis is that kidney spleen is insufficient, qi deficiency to blood stasis, damp evil of catching cold, caused by numbness resistance joint. The present invention has Yishen Jianpi, expelling wind and clearing away cold, promoting blood circulation dehumidifying, the effect removed obstruction in channels to relieve pain.It is good to treat knee osteoarthritis effect. The beneficial effects of the invention are as follows clinic application proves that curative for effect, safe without toxic side effect.
Embodiment
1st, formula and part by weight:15 parts of bark of ash, 20 parts of prepared rhizome of rehmannia, 12 parts of the root of herbaceous peony, 15 parts of Radix Angelicae Sinensis, the root of Chinese clematis 18 Part, 12 parts of paniculate swallowwort, 12 parts of radix cyathulae, 12 parts of levisticum, 18 parts of pawpaw, 20 parts of the Radix Astragali.
2nd, making and application method:Above-mentioned raw materials medicine is weighed in proportion and assorted, it is qualified to be processed with pharmaceutical equipment apparatus, carries It is standby that capsule is made after pure concentration is well mixed.

Claims (1)

  1. A kind of 1. capsule for treating knee osteoarthritis, it is characterized in that formula and part by weight are 15 parts of bark of ash, prepared rhizome of rehmannia 20 Part, 12 parts of the root of herbaceous peony, 15 parts of Radix Angelicae Sinensis, 18 parts of the root of Chinese clematis, 12 parts of paniculate swallowwort, 12 parts of radix cyathulae, 12 parts of levisticum, pawpaw 18 parts, 20 parts of the Radix Astragali;Above-mentioned raw materials medicine is weighed in proportion and assorted, it is qualified to be processed with pharmaceutical equipment apparatus, purification concentration system It is standby into capsule.
CN201610489215.3A 2016-06-20 2016-06-20 A kind of capsule for treating knee osteoarthritis Withdrawn CN107519294A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610489215.3A CN107519294A (en) 2016-06-20 2016-06-20 A kind of capsule for treating knee osteoarthritis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610489215.3A CN107519294A (en) 2016-06-20 2016-06-20 A kind of capsule for treating knee osteoarthritis

Publications (1)

Publication Number Publication Date
CN107519294A true CN107519294A (en) 2017-12-29

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CN201610489215.3A Withdrawn CN107519294A (en) 2016-06-20 2016-06-20 A kind of capsule for treating knee osteoarthritis

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113509519A (en) * 2021-08-13 2021-10-19 湖南省中医药研究院 Traditional Chinese medicine compound for treating knee osteoarthritis and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113509519A (en) * 2021-08-13 2021-10-19 湖南省中医药研究院 Traditional Chinese medicine compound for treating knee osteoarthritis and preparation method thereof
CN113509519B (en) * 2021-08-13 2022-07-26 湖南省中医药研究院 Traditional Chinese medicine compound for treating knee osteoarthritis and preparation method thereof

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Application publication date: 20171229