CN107519265A - One kind flu patch and preparation method thereof - Google Patents

One kind flu patch and preparation method thereof Download PDF

Info

Publication number
CN107519265A
CN107519265A CN201610954797.8A CN201610954797A CN107519265A CN 107519265 A CN107519265 A CN 107519265A CN 201610954797 A CN201610954797 A CN 201610954797A CN 107519265 A CN107519265 A CN 107519265A
Authority
CN
China
Prior art keywords
parts
patch
decoction
filtrate
dregs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610954797.8A
Other languages
Chinese (zh)
Inventor
王作飞
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GUIZHOU MIAOTONG BIOMEDICAL DEVELOPMENT CO LTD
Original Assignee
GUIZHOU MIAOTONG BIOMEDICAL DEVELOPMENT CO LTD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GUIZHOU MIAOTONG BIOMEDICAL DEVELOPMENT CO LTD filed Critical GUIZHOU MIAOTONG BIOMEDICAL DEVELOPMENT CO LTD
Priority to CN201610954797.8A priority Critical patent/CN107519265A/en
Publication of CN107519265A publication Critical patent/CN107519265A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses one kind flu patch, it is made up of the traditional Chinese medicinal material raw materials of following parts by weight:18 ~ 25 parts of honeysuckle, 18 ~ 25 parts of the capsule of weeping forsythia, 18 ~ 25 parts of balloonflower root, 18 ~ 25 parts of schizonepeta, 18 ~ 25 parts of radix bupleuri, 8 ~ 12 parts of semen armeniacae amarae, 8 ~ 12 parts of peppermint.Preparation method includes(1)Stock;(2)First time decoction is carried out, is filtrated to get first-time filtrate and a dregs of a decoction;(3)Carry out second to decoct, be filtrated to get secondary filtrate and the secondary dregs of a decoction;(4)Allocate, prepare patch:First-time filtrate and secondary filtrate are weighed, mixed preparing is carried out and obtains decoction and patch is made;(5)Manufactured patch is packed, you can.The present invention ensure that the effective component of crude drug using the method extraction decoction of decocting and concentrating;Prepare to patch use in and control outside, effectively prevent medicinal material and pass through side effect caused by intestines and stomach, blood absorption medicine;The present invention is easy to use, is attached on navel, simple to operate, easy to carry.

Description

One kind flu patch and preparation method thereof
Technical field
The present invention relates to one kind to treat cold medicine and preparation method thereof, and in particular to one kind flu patch and its preparation side Method, belong to technical field of Chinese medicine.
Background technology
Flu is the common disease in daily life, and the pharmaceutical preparation species that in the market is used to treat flu is various, but greatly Oral class or intramuscular injection, intravenous drip class medicine mostly, when taking oral class medicine thing, usually because medicine it is bitter, puckery etc. Smell, user is allowed to be difficult to swallow.And the side effect of oral class medicine thing is big, adverse reaction can be produced after taking, for muscle Injection, intravenous drip class medicine are, it is necessary to which medical professional is injected, drop operates, and can also have some side effects.
Therefore, a kind of patch for being used to treat flu is developed, good effect, avoids side effect, it is easy to use, safe and reliable Cold-treating preparation is highly desirable.
The content of the invention
The technical problem to be solved in the present invention is:A kind of flu patch and preparation method thereof is provided, the flu patch being prepared It is not only evident in efficacy, safe and reliable using the principle of inner disease outer treat, and use and carry, be easy to use, and flu patch system Preparation Method is simple.
The purpose of the present invention is achieved through the following technical solutions:
One kind flu patch, is made up of the traditional Chinese medicinal material raw materials of following parts by weight:18 ~ 25 parts of honeysuckle, 18 ~ 25 parts of the capsule of weeping forsythia, balloonflower root 18 ~ 25 parts, 18 ~ 25 parts of schizonepeta, 18 ~ 25 parts of radix bupleuri, 8 ~ 12 parts of semen armeniacae amarae, 8 ~ 12 parts of peppermint.
As preferable scheme, the parts by weight of each raw material are specially:20 parts of honeysuckle, 20 parts of the capsule of weeping forsythia, 20 parts of balloonflower root, schizonepeta 20 parts, 20 parts of radix bupleuri, 10 parts of semen armeniacae amarae, 10 parts of peppermint.
The preparation method of above-mentioned flu patch, comprises the following steps:
(1)Stock:Honeysuckle, the capsule of weeping forsythia, balloonflower root, schizonepeta, radix bupleuri, semen armeniacae amarae and peppermint are weighed up by proportioning, after cleaning respectively Drain;
(2)Carry out first time decoction:By step(1)Each raw material after draining is mixed, and is placed in decocting container, and it is medicine to add water Material is totally submerged, and is carried out decoction 1.5 ~ 2.0 hours, is filtered afterwards, obtains first-time filtrate and a dregs of a decoction;
(3)Second is carried out to decoct:To step(2)An obtained dregs of a decoction add water to medicinal material and are totally submerged, and are decocted again 1.0 ~ 1.5 hours, filtered afterwards, obtain secondary filtrate and the secondary dregs of a decoction;
(4)Allocate, prepare patch:Weigh first-time filtrate and secondary filtrate, carry out mixed preparing and obtain decoction, with can medically connect Patch is made in the decoction that the material absorption mixed preparing received obtains;
(5)Packaging:Manufactured patch is packed, you can.
Preferably, step(2)With(3)In, filtering uses the filter cloth of 140 mesh.
By honeysuckle, the capsule of weeping forsythia, balloonflower root, schizonepeta, radix bupleuri, semen armeniacae amarae and peppermint prepared by these Chinese medicine extract solutions by the present invention Form, there is clearing heat and detoxicating function, suitable for cold symptoms such as treatment nasal obstruction, runny nose, pharyngalgia, coughs.The present invention is prepared into The flu patch arrived, belongs to externally applied drug, is attached on navel during use.
Compared with prior art, beneficial effects of the present invention are as follows:The present invention extracts gold and silver using the method for decocting and concentrating Flower, the capsule of weeping forsythia, balloonflower root, schizonepeta, radix bupleuri, semen armeniacae amarae and the decoction of peppermint, ensure that the effective component of crude drug;What is prepared arrives Control in patch uses and outside, effectively prevent medicinal material and pass through side effect caused by intestines and stomach, blood absorption medicine;The present invention makes With conveniently, it is attached on navel, it is simple to operate, it is easy to carry.
Embodiment
Invention is described further with reference to specific embodiment:
Embodiment 1:
One kind flu patch, is made up of the traditional Chinese medicinal material raw materials of following parts by weight:18 parts of honeysuckle, 18 parts of the capsule of weeping forsythia, 18 parts of balloonflower root, schizonepeta 18 parts, 18 parts of radix bupleuri, 8 parts of semen armeniacae amarae, 8 parts of peppermint.
The preparation method of above-mentioned flu patch, comprises the following steps:
(1)Stock:Honeysuckle, the capsule of weeping forsythia, balloonflower root, schizonepeta, radix bupleuri, semen armeniacae amarae and peppermint are weighed up by proportioning, after cleaning respectively Drain;
(2)Carry out first time decoction:By step(1)Each raw material after draining is mixed, and is placed in decocting container, and it is medicine to add water Material is totally submerged, and decoct 1.5 hours, is filtered afterwards using the filter cloth of 140 mesh, obtain first-time filtrate and a medicine Slag;
(3)Second is carried out to decoct:To step(2)An obtained dregs of a decoction add water to medicinal material and are totally submerged, and are decocted again 1.0 hours, filtered afterwards using the filter cloth of 140 mesh, obtain secondary filtrate and the secondary dregs of a decoction;
(4)Allocate, prepare patch:Weigh first-time filtrate and secondary filtrate, carry out mixed preparing and obtain decoction, with can medically connect Patch is made in the decoction that the material absorption mixed preparing received obtains;
(5)Packaging:Manufactured patch is packed, you can.
Embodiment 2:
One kind flu patch, is made up of the traditional Chinese medicinal material raw materials of following parts by weight:20 parts of honeysuckle, 20 parts of the capsule of weeping forsythia, 20 parts of balloonflower root, schizonepeta 20 parts, 20 parts of radix bupleuri, 10 parts of semen armeniacae amarae, 10 parts of peppermint.
The preparation method of above-mentioned flu patch, comprises the following steps:
(1)Stock:Honeysuckle, the capsule of weeping forsythia, balloonflower root, schizonepeta, radix bupleuri, semen armeniacae amarae and peppermint are weighed up by proportioning, after cleaning respectively Drain;
(2)Carry out first time decoction:By step(1)Each raw material after draining is mixed, and is placed in decocting container, and it is medicine to add water Material is totally submerged, and decoct 1.8 hours, is filtered afterwards using the filter cloth of 140 mesh, obtain first-time filtrate and a medicine Slag;
(3)Second is carried out to decoct:To step(2)An obtained dregs of a decoction add water to medicinal material and are totally submerged, and are decocted again 1.3 hours, filtered afterwards using the filter cloth of 140 mesh, obtain secondary filtrate and the secondary dregs of a decoction;
(4)Allocate, prepare patch:Weigh first-time filtrate and secondary filtrate, carry out mixed preparing and obtain decoction, with can medically connect Patch is made in the decoction that the material absorption mixed preparing received obtains;
(5)Packaging:Manufactured patch is packed, you can.
Embodiment 3:
One kind flu patch, is made up of the traditional Chinese medicinal material raw materials of following parts by weight:25 parts of honeysuckle, 25 parts of the capsule of weeping forsythia, 25 parts of balloonflower root, schizonepeta 25 parts, 25 parts of radix bupleuri, 12 parts of semen armeniacae amarae, 12 parts of peppermint.
The preparation method of above-mentioned flu patch, comprises the following steps:
(1)Stock:Honeysuckle, the capsule of weeping forsythia, balloonflower root, schizonepeta, radix bupleuri, semen armeniacae amarae and peppermint are weighed up by proportioning, after cleaning respectively Drain;
(2)Carry out first time decoction:By step(1)Each raw material after draining is mixed, and is placed in decocting container, and it is medicine to add water Material is totally submerged, and decoct 2.0 hours, is filtered afterwards using the filter cloth of 140 mesh, obtain first-time filtrate and a medicine Slag;
(3)Second is carried out to decoct:To step(2)An obtained dregs of a decoction add water to medicinal material and are totally submerged, and are decocted again 1.5 hours, filtered afterwards using the filter cloth of 140 mesh, obtain secondary filtrate and the secondary dregs of a decoction;
(4)Allocate, prepare patch:Weigh first-time filtrate and secondary filtrate, carry out mixed preparing and obtain decoction, with can medically connect Patch is made in the decoction that the material absorption mixed preparing received obtains;
(5)Packaging:Manufactured patch is packed, you can.
Above content is to combine specific preferred embodiment further description made for the present invention, it is impossible to is assert The specific implementation of the present invention is confined to these explanations.For general technical staff of the technical field of the invention, On the premise of not departing from present inventive concept, some simple deduction or replace can also be made, should all be considered as belonging to the present invention's Protection domain.

Claims (4)

1. one kind flu patch, it is characterised in that be made up of the traditional Chinese medicinal material raw materials of following parts by weight:18 ~ 25 parts of honeysuckle, the capsule of weeping forsythia 18 ~ 25 parts, 18 ~ 25 parts of balloonflower root, 18 ~ 25 parts of schizonepeta, 18 ~ 25 parts of radix bupleuri, 8 ~ 12 parts of semen armeniacae amarae, 8 ~ 12 parts of peppermint.
A kind of 2. flu patch according to claim 1, it is characterised in that:The parts by weight of each raw material are specially:Honeysuckle 20 Part, 20 parts of the capsule of weeping forsythia, 20 parts of balloonflower root, 20 parts of schizonepeta, 20 parts of radix bupleuri, 10 parts of semen armeniacae amarae, 10 parts of peppermint.
3. the preparation method of a kind of patch of catching a cold according to claim 1 or 2, it is characterised in that comprise the following steps:
(1)Stock:Honeysuckle, the capsule of weeping forsythia, balloonflower root, schizonepeta, radix bupleuri, semen armeniacae amarae and peppermint are weighed up by proportioning, after cleaning respectively Drain;
(2)Carry out first time decoction:By step(1)Each raw material after draining is mixed, and is placed in decocting container, and it is medicine to add water Material is totally submerged, and is carried out decoction 1.5 ~ 2.0 hours, is filtered afterwards, obtains first-time filtrate and a dregs of a decoction;
(3)Second is carried out to decoct:To step(2)An obtained dregs of a decoction add water to medicinal material and are totally submerged, and are decocted again 1.0 ~ 1.5 hours, filtered afterwards, obtain secondary filtrate and the secondary dregs of a decoction;
(4)Allocate, prepare patch:Weigh first-time filtrate and secondary filtrate, carry out mixed preparing and obtain decoction, with can medically connect Patch is made in the decoction that the material absorption mixed preparing received obtains;
(5)Packaging:Manufactured patch is packed, you can.
A kind of 4. preparation method of patch of catching a cold according to claim 3, it is characterised in that:Step(2)With(3)In, filtering Using the filter cloth of 140 mesh.
CN201610954797.8A 2016-10-27 2016-10-27 One kind flu patch and preparation method thereof Pending CN107519265A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610954797.8A CN107519265A (en) 2016-10-27 2016-10-27 One kind flu patch and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610954797.8A CN107519265A (en) 2016-10-27 2016-10-27 One kind flu patch and preparation method thereof

Publications (1)

Publication Number Publication Date
CN107519265A true CN107519265A (en) 2017-12-29

Family

ID=60748557

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610954797.8A Pending CN107519265A (en) 2016-10-27 2016-10-27 One kind flu patch and preparation method thereof

Country Status (1)

Country Link
CN (1) CN107519265A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111067937A (en) * 2018-10-22 2020-04-28 广西小咕噜生物科技有限公司 Preparation method of plaster for treating children wind-heat type common cold

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1899422A (en) * 2006-07-12 2007-01-24 贵州山君生物工程有限公司 Process of rpreparing plaster for treating children cold

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1899422A (en) * 2006-07-12 2007-01-24 贵州山君生物工程有限公司 Process of rpreparing plaster for treating children cold

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111067937A (en) * 2018-10-22 2020-04-28 广西小咕噜生物科技有限公司 Preparation method of plaster for treating children wind-heat type common cold

Similar Documents

Publication Publication Date Title
CN104013910A (en) Traditional Chinese medicine composition for treating hypertension
CN103211962B (en) Chinese medicinal composition for treating anhypnia
CN104367632A (en) Small prescription for treating cold
CN103142982A (en) Medicine for treating acute upper respiratory infection
CN107519265A (en) One kind flu patch and preparation method thereof
CN103142987B (en) Medicament for treating mumps
CN103142959A (en) Medicament for treating urticaria
CN103041133A (en) Formula of traditional Chinese medicine for treating hysteria
CN103405504A (en) Traditional Chinese medicine granules for treating respiratory bovine infectious rhinotracheitis and preparation method thereof
CN102716419B (en) Compound oral liquid for developing intelligence and tonifying kidneys
CN103341044B (en) Itching-relieving compound preparation and preparation method thereof
CN101991776A (en) Chinese traditional medicine preparation for treating viral influenza
CN104547196A (en) Medicine for treating bone injury and bone fracture
CN104606650A (en) Traditional Chinese medicine composition treating insomnia
CN103157091A (en) Drug for treating empyrosis
CN103157090A (en) Medicament for treating diarrhea
CN103751621B (en) A kind of pharmaceutical preparation treating uterine bleeding
CN101336954A (en) Medicine composition for treating cold and preparation method thereof
CN101049346A (en) Medication for treating rhinitis and tympanitis, and preparation method
CN100998770A (en) Hypertensor plaster with tranquilizing function
CN106265985A (en) A kind of formula with Scolopendra as medicine and manufacture method
CN104825809A (en) Medicament for treating peripheral facial paralysis
CN103142984B (en) Medicine for treating rheumatism
CN108339020A (en) A kind of preparation method of three forks hardship injection
CN103142955A (en) Medicine for treating cold

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20171229