CN107485697A - 治疗膈肌痉挛的中药组合物 - Google Patents

治疗膈肌痉挛的中药组合物 Download PDF

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CN107485697A
CN107485697A CN201710823722.0A CN201710823722A CN107485697A CN 107485697 A CN107485697 A CN 107485697A CN 201710823722 A CN201710823722 A CN 201710823722A CN 107485697 A CN107485697 A CN 107485697A
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张海峰
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Henan university huaihe hospital
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Abstract

本案涉及一种治疗膈肌痉挛的中药组合物，所述中药组合物包括：鸡蛋参15‑25份、柿蒂10‑15份、桂枝7‑12份、辛夷5‑10份、法半夏9‑16份、马钱子8‑15份、醋南五味子6‑10份、浮萍10‑15、山兵豆7‑12份、紫花地丁4‑9份、野荞麦1‑3份、陈皮2‑5份、白茅根3‑6份、夏枯草3‑10份、路路通3‑5份、川楝子2‑6份、香附2‑8份、芙蓉菊根2‑5份、紫苏3‑6份、湿鼠曲草1‑5份、枇杷叶1‑3份、白芷1‑3份、肉苁蓉2‑6份、地盘松球1‑3份。能够脾胃寒湿、散寒止痛，具有疗效显著、见效快、无毒副作用、愈后不易复发的优点，经临床验证，本发明治疗膈肌痉挛有效率97.11％。

Description

治疗膈肌痉挛的中药组合物
技术领域
本发明涉及一种治疗膈肌痉挛的中药组合物，属中药领域。
背景技术
膈肌痉挛在临床表现上为呃逆，俗称打嗝，古称“哕”。其主要变现为喉间呃呃连声，声短而频，声音响亮，令人不能自主。呃逆主要是由膈肌引起的收缩运动，吸气时由于声门突然关闭而发出的一种短促的声音，可发于单侧或双侧的膈肌。吞咽动作过快、突然吞气或腹内压显著增高而引起呃逆，膈肌痉挛较轻者可自行消退。重者呃声频频，连续或间断发作，有的可持续较长时间而成为顽固性呃逆。目前，由于西药治疗膈肌痉挛效果不佳，并容易复发，且有较多副作用，因此，人们对有效治疗膈肌痉挛的中药存在很大的需求。
发明内容
针对现有技术中存在的技术问题，本案提供一种治疗膈肌痉挛的中药组合物，其通过选择合适的药材及其配比，达到安全有效治愈膈肌痉挛的目的。
为实现上述目的，本案通过以下技术方案实现：
一种治疗膈肌痉挛的中药组合物，其中，所述中药组合物包括：鸡蛋参15-25份、柿蒂10-15份、桂枝7-12份、辛夷5-10份、法半夏9-16份、马钱子8-15份、醋南五味子6-10份、浮萍10-15、山兵豆7-12份、紫花地丁4-9份、野荞麦1-3份、陈皮2-5份、白茅根3-6份、夏枯草3-10份、路路通3-5份、川楝子2-6份、香附2-8份、芙蓉菊根2-5份、紫苏3-6份、湿鼠曲草1-5份、枇杷叶1-3份、白芷1-3份。
优选的是，所述的治疗膈肌痉挛的中药组合物，其中，所述中药组合物还包括肉苁蓉2-6份。
优选的是，所述的治疗膈肌痉挛的中药组合物，其中，所述中药组合物还包括地盘松球1-3份。
优选的是，所述的治疗膈肌痉挛的中药组合物，其中，所述中药组合物具体为：
鸡蛋参15份、柿蒂10份、桂枝7份、辛夷5份、法半夏9份、马钱子8份、醋南五味子6份、浮萍10、山兵豆7份、紫花地丁4份、野荞麦1份、陈皮2份、白茅根3份、夏枯草3份、路路通3份、川楝子2份、香附2份、芙蓉菊根2份、紫苏3份、湿鼠曲草1份、枇杷叶1份、白芷1份、肉苁蓉2份、地盘松球1份。
优选的是，所述的治疗膈肌痉挛的中药组合物，其中，所述中药组合物具体为：
鸡蛋参25份、柿蒂15份、桂枝12份、辛夷10份、法半夏16份、马钱子15份、醋南五味子10份、浮萍15、山兵豆12份、紫花地丁9份、野荞麦3份、陈皮5份、白茅根6份、夏枯草10份、路路通5份、川楝子6份、香附8份、芙蓉菊根5份、紫苏6份、湿鼠曲草5份、枇杷叶3份、白芷3份、肉苁蓉6份、地盘松球3份。
优选的是，所述的治疗膈肌痉挛的中药组合物，其中，所述中药组合物具体为：
鸡蛋参20份、柿蒂12份、桂枝10份、辛夷6份、法半夏14份、马钱子12份、醋南五味子8份、浮萍12、山兵豆10份、紫花地丁6份、野荞麦2份、陈皮3份、白茅根5份、夏枯草6份、路路通4份、川楝子5份、香附6份、芙蓉菊根4份、紫苏5份、湿鼠曲草3份、枇杷叶2份、白芷2份、肉苁蓉5份、地盘松球2份。
一种中药组合物在治疗膈肌痉挛中的应用。
本发明的有益效果是：
本发明提供一种治疗膈肌痉挛的中药组合物，能够脾胃寒湿、散寒止痛，具有疗效显著、见效快、无毒副作用、愈后不易复发的优点，经临床验证，本发明治疗膈肌痉挛有效率97.11％。
具体实施方式
下面结合实施例对本发明做进一步的详细说明，以令本领域技术人员参照说明书文字能够据以实施。
实施例1
鸡蛋参15份、柿蒂10份、桂枝7份、辛夷5份、法半夏9份、马钱子8份、醋南五味子6份、浮萍10、山兵豆7份、紫花地丁4份、野荞麦1份、陈皮2份、白茅根3份、夏枯草3份、路路通3份、川楝子2份、香附2份、芙蓉菊根2份、紫苏3份、湿鼠曲草1份、枇杷叶1份、白芷1份、肉苁蓉2份、地盘松球1份。
其制备方法为：
将鸡蛋参、柿蒂、桂枝、辛夷、法半夏、马钱子、醋南五味子、浮萍、山兵豆、紫花地丁、野荞麦、陈皮、白茅根、夏枯草、路路通、川楝子、香附、芙蓉菊根、紫苏、湿鼠曲草、枇杷叶、白芷、肉苁蓉、地盘松球混合，加水煎煮两次，第一次加8倍量水，煎煮2小时，第二次加6倍量水，煎煮1.5小时，合并煎液，过滤，得汤剂。
实施例2
鸡蛋参25份、柿蒂15份、桂枝12份、辛夷10份、法半夏16份、马钱子15份、醋南五味子10份、浮萍15、山兵豆12份、紫花地丁9份、野荞麦3份、陈皮5份、白茅根6份、夏枯草10份、路路通5份、川楝子6份、香附8份、芙蓉菊根5份、紫苏6份、湿鼠曲草5份、枇杷叶3份、白芷3份、肉苁蓉6份、地盘松球3份。
其制备方法为：
将鸡蛋参、柿蒂、桂枝、辛夷、法半夏、马钱子、醋南五味子、浮萍、山兵豆、紫花地丁、野荞麦、陈皮、白茅根、夏枯草、路路通、川楝子、香附、芙蓉菊根、紫苏、湿鼠曲草、枇杷叶、白芷、肉苁蓉、地盘松球混合，加水煎煮两次，第一次加10倍量水，煎煮3小时，第二次加8倍量水，煎煮2小时，合并煎液，过滤，得汤剂。
实施例3
鸡蛋参20份、柿蒂12份、桂枝10份、辛夷6份、法半夏14份、马钱子12份、醋南五味子8份、浮萍12、山兵豆10份、紫花地丁6份、野荞麦2份、陈皮3份、白茅根5份、夏枯草6份、路路通4份、川楝子5份、香附6份、芙蓉菊根4份、紫苏5份、湿鼠曲草3份、枇杷叶2份、白芷2份、肉苁蓉5份、地盘松球2份。
其制备方法为：
将鸡蛋参、柿蒂、桂枝、辛夷、法半夏、马钱子、醋南五味子、浮萍、山兵豆、紫花地丁、野荞麦、陈皮、白茅根、夏枯草、路路通、川楝子、香附、芙蓉菊根、紫苏、湿鼠曲草、枇杷叶、白芷、肉苁蓉、地盘松球混合，加水煎煮两次，第一次加9倍量水，煎煮2.5小时，第二次加6倍量水，煎煮1.5小时，合并煎液，过滤，得汤剂。
实施例4本发明药物的动物毒性试验报告
取大鼠40只，雌雄兼用，体重200-240g，分两组，每组20只，其中一组为超剂量试验组，另一组为正常量试验组。超常量组为30ml/kg，正常量为15ml/kg，给药方式为灌胃法给药，每天3次，连服7天，每天观察给药反应，结果表明二组大鼠活动、饮食正常，药物无不良毒副作用。
实施例5本发明药物的临床观察资料
1、一般资料
收治门诊患者173例，年龄10-65岁。
2、诊断标准
①常有进食过冷、过热、过于辛辣，或情志郁怒等诱因可询。
②以呃逆为主症，呃声频频，呈持续状态不能自制，可伴呕吐，情绪紧张，胸膈脘腹间疼痛，或有嗳气，纳呆，甚则厌食或拒食，不寐等症。
③偶发呃逆，或病危胃气将绝时之呃逆，均属短暂症状，不列为呃逆病。
④X线钡餐及胃镜等检查无器质性病变征象。
3、治疗方法
选用上述药剂，给患者服用，每次服用1剂，每天早、晚各服1次，5天为一个疗程，连续服用3个疗程。
4、疗效评定标准
痊愈：临床症状和体征完全消失或基本消失，观察一年无复发者；
显效：临床症状和体征大部分好转或明显好转；
无效；临床症状和体征均无明显改善，症状如前，效果不明显。
5、治疗结果(见下表)
在上述的治疗中，用本发明药物治疗膈肌痉挛患者173例，结果痊愈158例，痊愈率为91.32％，显效10例，显效率为5.78％，无效5例，总有效率为97.11％。
尽管本发明的实施方案已公开如上，但其并不仅仅限于说明书和实施方式中所列运用，它完全可以被适用于各种适合本发明的领域，对于熟悉本领域的人员而言，可容易地实现另外的修改，因此在不背离权利要求及等同范围所限定的一般概念下，本发明并不限于特定的细节。

Claims (7)

1.一种治疗膈肌痉挛的中药组合物，其特征在于，所述中药组合物包括：鸡蛋参15-25份、柿蒂10-15份、桂枝7-12份、辛夷5-10份、法半夏9-16份、马钱子8-15份、醋南五味子6-10份、浮萍10-15、山兵豆7-12份、紫花地丁4-9份、野荞麦1-3份、陈皮2-5份、白茅根3-6份、夏枯草3-10份、路路通3-5份、川楝子2-6份、香附2-8份、芙蓉菊根2-5份、紫苏3-6份、湿鼠曲草1-5份、枇杷叶1-3份、白芷1-3份。
2.如权利要求1所述的治疗膈肌痉挛的中药组合物，其特征在于，所述中药组合物还包括肉苁蓉2-6份。
3.如权利要求2所述的治疗膈肌痉挛的中药组合物，其特征在于，所述中药组合物还包括地盘松球1-3份。
4.如权利要求3所述的治疗膈肌痉挛的中药组合物，其特征在于，所述中药组合物具体为：
鸡蛋参15份、柿蒂10份、桂枝7份、辛夷5份、法半夏9份、马钱子8份、醋南五味子6份、浮萍10、山兵豆7份、紫花地丁4份、野荞麦1份、陈皮2份、白茅根3份、夏枯草3份、路路通3份、川楝子2份、香附2份、芙蓉菊根2份、紫苏3份、湿鼠曲草1份、枇杷叶1份、白芷1份、肉苁蓉2份、地盘松球1份。
5.如权利要求3所述的治疗膈肌痉挛的中药组合物，其特征在于，所述中药组合物具体为：
鸡蛋参25份、柿蒂15份、桂枝12份、辛夷10份、法半夏16份、马钱子15份、醋南五味子10份、浮萍15、山兵豆12份、紫花地丁9份、野荞麦3份、陈皮5份、白茅根6份、夏枯草10份、路路通5份、川楝子6份、香附8份、芙蓉菊根5份、紫苏6份、湿鼠曲草5份、枇杷叶3份、白芷3份、肉苁蓉6份、地盘松球3份。
6.如权利要求3所述的治疗膈肌痉挛的中药组合物，其特征在于，所述中药组合物具体为：
鸡蛋参20份、柿蒂12份、桂枝10份、辛夷6份、法半夏14份、马钱子12份、醋南五味子8份、浮萍12、山兵豆10份、紫花地丁6份、野荞麦2份、陈皮3份、白茅根5份、夏枯草6份、路路通4份、川楝子5份、香附6份、芙蓉菊根4份、紫苏5份、湿鼠曲草3份、枇杷叶2份、白芷2份、肉苁蓉5份、地盘松球2份。
7.一种如权利要求3-6中任一项所述的中药组合物在治疗膈肌痉挛中的应用。
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