CN107469226A - Pulmonary surfactant doser - Google Patents

Pulmonary surfactant doser Download PDF

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Publication number
CN107469226A
CN107469226A CN201710827136.3A CN201710827136A CN107469226A CN 107469226 A CN107469226 A CN 107469226A CN 201710827136 A CN201710827136 A CN 201710827136A CN 107469226 A CN107469226 A CN 107469226A
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CN
China
Prior art keywords
delivery conduit
pulmonary surfactant
injection
supporter
medicine liquid
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710827136.3A
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Chinese (zh)
Inventor
陆文超
陈永政
张梅
殷志爽
马芹芹
吕金玲
张冬燕
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China Resources Double Crane Pharmaceutical Co Ltd
Original Assignee
China Resources Double Crane Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by China Resources Double Crane Pharmaceutical Co Ltd filed Critical China Resources Double Crane Pharmaceutical Co Ltd
Priority to CN201710827136.3A priority Critical patent/CN107469226A/en
Publication of CN107469226A publication Critical patent/CN107469226A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/04Liquids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/1025Respiratory system
    • A61M2210/1039Lungs

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The present invention relates to a kind of pulmonary surfactant doser, including:Inject supporter (10) and delivery conduit (20), one end of the delivery conduit (20) is connected with the injection supporter (10) and internal connection, for the decoction for the pulmonary surfactant being injected into the injection supporter (10) to be directed into neonatal dispenser position, the stub area of the delivery conduit (20) is provided with multiple medicine liquid outlets.The present invention is provided with multiple medicine liquid outlets in the stub area of delivery conduit, compared to the form that existing PS delivery catheters use single medicine liquid outlet, other medicine liquid outlets still can smoothly be administered when when part, medicine liquid outlet blocks, and when syringe presses input decoction, decoction from multiple medicine liquid outlets eject when, impulsive force can accordingly mitigate, so as to avoid the possibility for causing injury of lungs or decoction adverse current as far as possible.

Description

Pulmonary surfactant doser
Technical field
The present invention relates to medical instruments field, more particularly to a kind of pulmonary surfactant (Pulmonary Surfactant, abbreviation PS) doser.
Background technology
In the treatment of the relevant disease of premature neonate, such as respiratory distress syndrome of newborn (Newborn Respiratory Distress Syndrome, abbreviation NRDS), ARDS (Acute Respiratory Distress Syndrome, abbreviation ARDS), Neonatal Meconium Aspiration Syndrome (Meconium Aspiration Syndrome, abbreviation MAS), congenital pulmonary hypoplasia, severe pneumonia etc., can be by PS by airway administration to lung, to reduce Pulmonary surface tension, prevent alveolar collapse and pulmonary edema.
Mainly by way of trachea cannula administration, this mode easily causes pulmonary lesion, and deposits for administration at present Not convenient, the administration uncontrollable problem of material is being administered, when being intubated through organ it may also happen that adverse current.In order to The defects of overcoming existing trachea cannula to be administered, the conduit that there has been using reduced size are carried out by the way of pulmonary administration. As shown in figure 1, be the structural representation of existing PS delivery catheters, this conduit is by the supporter a1 and flexible pipe that are connected with each other A2 is formed, and supporter a1 is used to connect the syringe for accommodating PS, and flexible pipe a2 is provided with multiple scale a3, to assist to use Person determines the depth of conduit insertion.It is as follows but this conduit needs to overcome there are still some defects:
1st, because conduit is thinner, the medicine liquid outlet blocking of catheter tip easily occurs when in use and can not smoothly be administered Problem, and syringe press input decoction when, compared with the decoction in slim pipe diameter from medicine liquid outlet eject when pressure may The problem of causing injury of lungs, while decoction adverse current also easily occurs.
2nd, conduit after such insertion, can only rely on the scale of conduit exposed portion and feeling to determine working as conduit for user Preceding insertion position, administering position may be caused to be not suitable for when position judgment inaccuracy or cause injury of lungs.
3rd, supporter is only suitable for the syringe use of specific standard, it is necessary to configure for the syringe of different size The PS delivery catheters of multiple corresponding specifications.
The content of the invention
The purpose of the present invention is to propose to a kind of pulmonary surfactant doser, can smoothly realize pulmonary administration, and Pulmonary lesion is avoided as far as possible.
To achieve the above object, the invention provides a kind of pulmonary surfactant doser, including:Inject supporter And delivery conduit, one end of the delivery conduit is connected with the injection supporter and internal connection, for injecting branch by described The decoction for the pulmonary surfactant being injected into support body is directed to neonatal dispenser position, the end region of the delivery conduit Domain is provided with multiple medicine liquid outlets, the eject position of the decoction for sharing pulmonary surfactant, to mitigate rushing for medical liquid spraying Power is hit, so as to avoid the decoction of injection from causing to damage to neonatal lung.
Further, the multiple medicine liquid outlet includes the first medicine for being arranged on the pipe shaft distal end faces of the delivery conduit Liquid exports and is arranged on the second medicine liquid outlet of the pipe shaft side of the stub area of the delivery conduit.
Further, the quantity of second medicine liquid outlet is one.
Further, second medicine liquid outlet has multiple, and the difference for being distributed in the pipe shaft of the delivery conduit is female On line and different transversal planes.
Further, second medicine liquid outlet is not more than relative to the recessed depth of the delivery conduit outer surface profile The 3/5 of the diameter of the delivery conduit.
Further, second medicine liquid outlet is not more than relative to the recessed depth of the delivery conduit outer surface profile The 1/2 of the diameter of the delivery conduit.
Further, the pipe shaft distal end faces of the delivery conduit are formed as rounding.
Further, the rounding is R3~R5.
Further, the stub area is the region of 0~20mm from the pipe shaft distal end faces of the delivery conduit.
Further, the delivery conduit is provided with multiple scales, and the latter end scale in the multiple scale includes curing Treat the development scale of development.
Further, 5~15mm of pipe shaft distal end faces of delivery conduit described in the development graduation range.
Further, the inner surface profile of the injection supporter includes conical Internal periphery, to be adapted to different size Syringe.
Further, the outer surface profile of the injection supporter includes conical outer profile, and with it is described it is conical in Profile matches, and is provided with that spiral shape is raised or multigroup annular protrusion on the outer surface profile.
Further, the conical Internal periphery of the injection supporter is made up of the conical section of multiple different tapers, is leaned on The taper of the conical section of the nearly delivery conduit side is more than the conical section away from the delivery conduit side.
Further, the lid for covering injection port is additionally provided with the injection supporter, the lid is connected by flexible piece It is connected on the injection supporter, to maintain the germ-free condition of the pulmonary surfactant doser, and can injecting The injection port on the injection supporter is stoppered afterwards, to avoid decoction adverse current.
Further, the injection supporter is connected or is made into integration by bonding mode with the delivery conduit.
Further, the entirety of the injection supporter or local in colour.
Further, length direction of the stub area of the delivery conduit along the delivery conduit be provided with being capable of obvious area Not in the delivery conduit other parts continuous dark signs, length and the neonate's tracheae of the continuous dark signs are grown Degree matches.
Based on above-mentioned technical proposal, the present invention is provided with multiple medicine liquid outlets in the stub area of delivery conduit, compared to Existing PS delivery catheters use the form of single medicine liquid outlet, other medicine liquid outlets when medicine liquid outlet blocks when part Still can smoothly be administered, and syringe press input decoction when, decoction from multiple medicine liquid outlets eject when, pressure meeting It is corresponding to mitigate, so as to avoid the possibility for causing injury of lungs or decoction adverse current as far as possible.
Brief description of the drawings
Accompanying drawing described herein is used for providing a further understanding of the present invention, forms the part of the application, this hair Bright schematic description and description is used to explain the present invention, does not form inappropriate limitation of the present invention.In the accompanying drawings:
Fig. 1 is the structural representation of existing PS delivery catheters.
Fig. 2 is overall structure and the partial enlargement signal of an embodiment of pulmonary surfactant doser of the present invention Figure.
Fig. 3 is overall structure and the partial enlargement signal of another embodiment of pulmonary surfactant doser of the present invention Figure.
Fig. 4 is overall structure and the partial enlargement signal of the another embodiment of pulmonary surfactant doser of the present invention Figure.
Fig. 5 is the schematic diagram in AA sections in Fig. 2.
Embodiment
Below by drawings and examples, technical scheme is described in further detail.
As shown in Fig. 2 the overall structure and part for an embodiment of pulmonary surfactant doser of the present invention are put Big schematic diagram.AA sections with reference to shown in Fig. 4, pulmonary surfactant doser (the rear abbreviation PS administrations dress of the present embodiment Put) include:Inject supporter 10 and delivery conduit 20.Wherein, injection supporter 10 can be formed as one and be easy to hand-held branch Support structure, to facilitate operator to connect the syringe on injection supporter 10, and it can be injected to the inside of injection supporter PS decoctions.One end of delivery conduit 20 be connected with the injection supporter 10 and internal connection, for by the injection supporter The decoction for the pulmonary surfactant being injected into 10 is directed to neonatal dispenser position.
Injection supporter 10 and delivery conduit 20 can use identical material, can also use unlike material, such as PVC, FEP, PP, Silicone, TPU or PFA etc..For example, the hardness of delivery conduit 20 can be 60~90A, and caliber can be 1.5 ~4.0mm, pipe range can be within 250mm.But in various embodiments, the dimension of delivery conduit 20 is not limited to this reality Example.The pipe shaft distal end faces of delivery conduit 20 are preferably formed into rounding (such as R3~R5), to facilitate insertion, while also try one's best Reduce or avoid damage of the delivery conduit 20 to tissue.
It can be seen that, the stub area of delivery conduit 20 is provided with multiple medicine liquid outlets from the amplifier section shown in Fig. 2.It is right For thinner delivery conduit 20, these medicine liquid outlets can share the outgoing position of PS decoctions, be gone out with mitigating single decoction The impulsive force of PS decoctions that mouth is ejected, avoids impulsive force excessive and causes neonatal lung to damage, can also reduce as far as possible or Avoid the generation of decoction adverse current.And when the part medicine liquid outlet in multiple medicine liquid outlets blocks, remaining medicine liquid outlet It can then continue to realize administration, so that it is guaranteed that neonatal lung administration process is smoothed out.
Multiple medicine liquid outlets are distributed in the stub area of delivery conduit 20, that is, refer to the pipe shaft distal end faces from delivery conduit 20 The region of a segment length is played, the segment length is preferably 0~20mm.The selection of this zone length is it is contemplated that the number of medicine liquid outlet The factors such as amount, distributing position, administering position, the quantity and set location of medicine liquid outlet can then be set according to actual administration needs Meter.The arrangement examples of medicine liquid outlet with reference to shown in figure 2, multiple medicine liquid outlets can include the pipe shaft end for being arranged on delivery conduit 20 Second medicine liquid outlet of the pipe shaft side of the first medicine liquid outlet 22a for holding end face and the stub area for being arranged on delivery conduit 20 22b、22c.The structure of single medicine liquid outlet is arranged using pipe shaft distal end faces compared to existing PS conduits, in the present embodiment The second medicine liquid outlet 22b and 22c can be effectively reduced injection pressure of the decoction in pulmonary position, reduce pulmonary lesion, and And it can also realize larger range of pulmonary administration.
Second medicine liquid outlet of the pipe shaft side wall for being arranged on delivery conduit 20 can have multiple, these second decoctions On the different buses and different transversal planes for exporting the pipe shaft that can be distributed in delivery conduit 20, so that it is guaranteed that decoction can more apply The uniform and greater area of administering position of covering.It can be observed from fig. 2 that the second medicine liquid outlet 22b is located at a top side pipe in figure Body side wall is closer to inject the side of supporter 10, and the second medicine liquid outlet 22c is then located in figure side pipe shaft side wall on the lower Further from injection supporter 10 side, when decoction gushes under the pressure effect of syringe to the end of delivery conduit 20 to be come, Then can be simultaneously from the first medicine liquid outlet 22a of distal end faces and the second medicine liquid outlet of upper and lower both sides different length position 22b and 22c are ejected, it is achieved thereby that evenly and larger range of administration.Even if the first medicine liquid outlet 22a or the second medicine Liquid outlet 22b or 22c is blocked, and decoction can also spray from unplugged medicine liquid outlet, so that it is guaranteed that smoothly administration.
In an alternative embodiment as shown in fig. 3, positioned at delivery conduit 20 pipe shaft side wall the second medicine liquid outlet number Measure as one, that is to say, that the delivery conduit 20 of the PS dosers of the embodiment only has the first decoction of pipe shaft distal end faces Export 22a and be arranged on a second medicine liquid outlet 22b of the pipe shaft side of the stub area of the delivery conduit 20.And institute It is with only setting the reason for second medicine liquid outlet, for employing delivery conduit 20 made of softer easily broken material Say, when setting multiple second medicine liquid outlets, if each second medicine liquid outlet is closer to the distance, when in use easily by external force Effect and be broken, cause the unsafe condition in fines left neonate, and if by between each second medicine liquid outlet away from From increasing, be then possible to some second medicine liquid outlets in the outer part again apart from pulmonary administration position farther out, when decoction enter it is defeated After sending conduit, there is part decoction to be discharged from these second medicine liquid outlets, therefore reduce the amount of liquid medicine for reaching pulmonary administration position. And the present embodiment only delivery conduit 20 pipe shaft side wall set second medicine liquid outlet, then eliminate above-mentioned conduit rupture or The problem of person's dosage is reduced.
In above-mentioned PS dosers embodiment, each second medicine liquid outlet is relative to the recessed of delivery conduit outer surface profile Diameter D 3/5 (with reference to the figure 3) of delivery conduit 20 can not be more than by entering depth h, in order to avoid delivery conduit 20 is become easily in decoction Exit fractures, and causes the relic of delivery conduit 20 to be retained in human body, and further preferred second medicine liquid outlet is relative to conveying 1/2 of the recessed depth of catheter outer surface profile no more than the diameter of delivery conduit 20, to reduce using PS administration dresses as far as possible Broken pipe risk occurs when putting.
User in order to facilitate operation PS dosers can easily understand the insertion depth of delivery conduit 20, can be with Multiple scales 21 are set on delivery conduit 20, and scale 21 can be identified according to standard size interval, and identification means can be with Using word, numeral and/or the symbol (such as lines, rectangle, circle etc.) that can substantially recognize.These scales can be distributed in away from In the range of 10~200mm of latter end of delivery conduit 20, so as to user can be finer adjustment delivery conduit insertion Depth.
In these scales 21, preferably including in latter end scale can the medical development scale 21 ' to develop.So in user When with reference to medical developing apparatus insert the operation of the delivery conduit of PS dosers, the mode using medical treatment development is directly perceived The current position in neonate of development scale 21 ' is known on ground, due to the end of the development scale 21 ' and delivery conduit 20 with And the distance of each medicine liquid outlet is previously known, therefore user can easily deduce delivery conduit 20 in neonate Position, in conjunction with neonate inner tissue medical treatment develop, then can realize that position is more accurately administered.
Itself there is certain flexibility in view of delivery conduit 20, and if the scale 21 ' that develops is last apart from delivery conduit 20 Then possible accuracy can be affected too far at end, therefore preferred development scale 21 ' is apart from the pipe shaft distal end faces 5 of delivery conduit 20 ~15mm.This makes it possible to the accuracy for further improving administering position, improves therapeutic effect, and reduces the waste of PS decoctions, Also damage of the delivery conduit 20 to tissue is reduced or avoided as far as possible.
In another embodiment shown in Fig. 4, can delivery conduit 20 stub area along the delivery conduit 20 Length direction the continuous dark signs 25 of the other parts that can be clearly distinguishable from the delivery conduit 20 are set, it is described continuous The length of dark signs 25 matches with neonate's air tubing length.Here continuous dark signs 25 are along delivery conduit 20 The continuous dark signs of length direction, and can be continuously or discontinuously in the circumference of delivery conduit 20.When medical personnel are When neonate is intubated, it can observe whether the continuous dark signs 25 have just been inserted by way of range estimation or laryngoscope observation Enter into neonatal glottis, because the continuous dark signs 25 visually easily distinguish, and its length and neonate's tracheae Length matches, therefore medical personnel operationally can be more convenient and accurate, and the insertion depth realized can have Avoid to effect it is too deep or excessively shallow insertion when the problem of decoction can not being sent to administering position.
Be previously mentioned that injection supporter 10 when in use often by user's hand-held, and need connection filled with The syringe of PS decoctions, therefore in the PS doser embodiments of the present invention, the inner surface wheel preferably in injection supporter 10 Exterior feature includes conical Internal periphery 13 (referring to Fig. 5).The conical Internal periphery 13 connects with injecting the injection port of supporter 10, and The syringe of the different size from injection port insertion can be adapted to.For the syringe of different size, influence is simply noted Emitter is inserted into the depth of the injection port of injection supporter 10, the normal injection without influenceing syringe, so as to reduce or keep away Exempt to release caused by when injecting supporter 10 and syringe and mismatching and liquid medicine spill.
In order to coordinate the force direction of syringe, preferably include in the outer surface profile of injection supporter 10 outside conical Profile 14, and the conical outer profile 14 matches with conical Internal periphery 13.By taking Fig. 5 as an example, conical outer profile 14 can be with Supporting surface is provided for the finger of user.User can use the part of grip finger conical outer profile, finger in injection The right direction horizontal component of the clamping force of conical outer profile 14 can resist right side syringe to the left horizontal direction squeeze Pressure, so as to also improve the efficiency of injecting liquid drug while convenient exert a force.Applied in view of finger on conical outer profile Easily skidded during plus-pressure, therefore the multigroup annular protrusion 11 shown in Fig. 2 is set preferably on outer surface profile, or Spiral shape is raised.These annular protrusions 11 or spiral shape projection can increase contacts surface between finger and injection supporter 10 Resistance, with as far as possible avoid injection when finger skid, and then prevent inject when delivery conduit 20 insertion depth become It is dynamic.Meanwhile this bulge-structure can also facilitate taking-up of the PS dosers out of neonate.
For the conical Internal periphery 13 for injecting supporter 10, it can be by the conical section structure of multiple different tapers Into the taper close to the conical section of the side of delivery conduit 20 is more than the cone away from the side of delivery conduit 20 Section, the injection nozzle and injection supporter 10 that can so make syringe fit more closely against, and can also slow down ejection power Caused pressure.
In fig. 2, the lid 12 that may be provided for covering injection port on supporter 10 is injected, the lid 12 passes through flexible piece 15 are connected on injection supporter 10.The form of lid 12 may be configured as the conical Internal periphery 13 and/or note with injection supporter The cone-shaped plug that the Internal periphery of loophole matches, so as to successfully be inserted in the injection port of injection supporter 10, and stopper Injection port.Before injection, PS dosers of the present invention may be accommodated in aseptic package bag, and PS is administered when an injection is needed Device takes out from aseptic package bag, and lid 12 can maintain the germ-free condition of PS dosers, and after injection by noting Lid 12 is stoppered on loophole, decoction adverse current can be effectively prevented from.In addition, no matter whether lid 12 covers, can effectively increase The transverse width of supporter 10 is injected, therefore the risk that whole PS dosers slip into can be reduced as far as possible.
In the processing of injection supporter 10 and delivery conduit 20, the injection supporter 10 and defeated shown in Fig. 5 can be used The mode for sending conduit 20 to be made into integration, manufacture injection supporter 10 and delivery conduit respectively can also be used in other embodiments 20, and delivery conduit 20 is inserted into inside injection supporter 10, then both are connected by bonding mode and is integral.Injection Locating surface can be then set accordingly inside supporter 10 to realize delivery conduit 20 relative to the fixation of injection supporter 10 and determine Position.
In addition, in order to clearly pick out PS dosers under different light conditions, can be in manufacture injection branch During support body, make the entirety of injection supporter that colour can also be set in the part of injection supporter, such as set color in colour Vitta line etc..
Finally it should be noted that:The above embodiments are merely illustrative of the technical scheme of the present invention and are not intended to be limiting thereof;To the greatest extent The present invention is described in detail with reference to preferred embodiments for pipe, those of ordinary skills in the art should understand that:Still The embodiment of the present invention can be modified or equivalent substitution is carried out to some technical characteristics;Without departing from this hair The spirit of bright technical scheme, it all should cover among the claimed technical scheme scope of the present invention.

Claims (18)

  1. A kind of 1. pulmonary surfactant doser, it is characterised in that including:Inject supporter (10) and delivery conduit (20), one end of the delivery conduit (20) be connected and internal connection with the injection supporter (10), for by the injection The decoction for the pulmonary surfactant being injected into supporter (10) is directed to neonatal dispenser position, the delivery conduit (20) stub area is provided with multiple medicine liquid outlets, the eject position of the decoction for sharing pulmonary surfactant, to mitigate The impulsive force of medical liquid spraying, so as to avoid the decoction of injection from causing to damage to neonatal lung.
  2. 2. pulmonary surfactant doser according to claim 1, it is characterised in that the multiple medicine liquid outlet bag Include the first medicine liquid outlet (22a) for the pipe shaft distal end faces for being arranged on the delivery conduit (20) and be arranged on the delivery conduit (20) the second medicine liquid outlet (22b, 22c) of the pipe shaft side of stub area.
  3. 3. pulmonary surfactant doser according to claim 2, it is characterised in that second medicine liquid outlet The quantity of (22b, 22c) is one.
  4. 4. pulmonary surfactant doser according to claim 2, it is characterised in that second medicine liquid outlet (22b, 22c) has multiple, and is distributed on the different buses and different transversal planes of the pipe shaft of the delivery conduit (20).
  5. 5. the pulmonary surfactant doser according to Claims 2 or 3 or 4, it is characterised in that second decoction Outlet (22b, 22c) is not more than the delivery conduit (20) relative to the recessed depth of the delivery conduit (20) outer surface profile Diameter 3/5.
  6. 6. pulmonary surfactant doser according to claim 5, it is characterised in that second medicine liquid outlet (22b, 22c) is straight no more than the delivery conduit (20) relative to the recessed depth of the delivery conduit (20) outer surface profile The 1/2 of footpath.
  7. 7. pulmonary surfactant doser according to claim 1, it is characterised in that the delivery conduit (20) Pipe shaft distal end faces are formed as rounding.
  8. 8. pulmonary surfactant doser according to claim 7, it is characterised in that the rounding be R3~ R5。
  9. 9. pulmonary surfactant doser according to claim 1, it is characterised in that the stub area is from institute The pipe shaft distal end faces for stating delivery conduit (20) play 0~20mm region.
  10. 10. pulmonary surfactant doser according to claim 1, it is characterised in that the delivery conduit (20) Be provided with multiple scales (21), the latter end scale in the multiple scale (21) include can medical treatment development development scale (21 ').
  11. 11. pulmonary surfactant doser according to claim 10, it is characterised in that the development scale 5~the 15mm of pipe shaft distal end faces of (21 ') apart from the delivery conduit (20).
  12. 12. pulmonary surfactant doser according to claim 1, it is characterised in that the injection supporter (10) inner surface profile includes conical Internal periphery (13), to be adapted to the syringe of different size.
  13. 13. pulmonary surfactant doser according to claim 12, it is characterised in that the injection supporter (10) outer surface profile includes conical outer profile (14), and matches with the conical Internal periphery (13), described outer Surface profile is provided with that spiral shape is raised or multigroup annular protrusion (11).
  14. 14. pulmonary surfactant doser according to claim 12, it is characterised in that the injection supporter (10) conical Internal periphery (13) is made up of the conical section of multiple different tapers, close to the delivery conduit (20) side The taper of conical section is more than the conical section away from the delivery conduit (20) side.
  15. 15. pulmonary surfactant doser according to claim 1, it is characterised in that the injection supporter (10) lid (12) for covering injection port is additionally provided with, the lid (12) is connected to the injection by flexible piece (15) and supported On body (10), to maintain the germ-free condition of the pulmonary surfactant doser, and it can stopper after injection described The injection port on supporter (10) is injected, to avoid decoction adverse current.
  16. 16. pulmonary surfactant doser according to claim 1, it is characterised in that the injection supporter (10) it is connected or is made into integration by bonding mode with the delivery conduit (20).
  17. 17. pulmonary surfactant doser according to claim 1, it is characterised in that the injection supporter It is overall or local in colour.
  18. 18. pulmonary surfactant doser according to claim 1, it is characterised in that the delivery conduit (20) Length direction of the stub area along the delivery conduit (20) be provided with its that can be clearly distinguishable from the delivery conduit (20) The continuous dark signs (25) of his part, the length of the continuous dark signs (25) match with neonate's air tubing length.
CN201710827136.3A 2017-09-14 2017-09-14 Pulmonary surfactant doser Pending CN107469226A (en)

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Application Number Priority Date Filing Date Title
CN201710827136.3A CN107469226A (en) 2017-09-14 2017-09-14 Pulmonary surfactant doser

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Application Number Priority Date Filing Date Title
CN201710827136.3A CN107469226A (en) 2017-09-14 2017-09-14 Pulmonary surfactant doser

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Publication Number Publication Date
CN107469226A true CN107469226A (en) 2017-12-15

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CN201710827136.3A Pending CN107469226A (en) 2017-09-14 2017-09-14 Pulmonary surfactant doser

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006239260A (en) * 2005-03-07 2006-09-14 Hakko Co Ltd Medical solution syringe device
CN1956745A (en) * 2004-04-20 2007-05-02 亚罗擎公司 Aerosol delivery apparatus, method and preparation for pressure-assisted breathing systems
CN201179266Y (en) * 2008-04-07 2009-01-14 陈延平 Hydrojet device for uterine cavity detection
CN203777478U (en) * 2014-03-13 2014-08-20 李明 Medicine spraying device for respiratory medicine
CN205729935U (en) * 2015-02-13 2016-11-30 凯西制药公司 For using the conduit of pulmonary surfactant
CN206275904U (en) * 2016-08-29 2017-06-27 高永利 A kind of anesthetic tube
CN208511694U (en) * 2017-09-14 2019-02-19 华润双鹤药业股份有限公司 Pulmonary surfactant drug delivery device

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1956745A (en) * 2004-04-20 2007-05-02 亚罗擎公司 Aerosol delivery apparatus, method and preparation for pressure-assisted breathing systems
JP2006239260A (en) * 2005-03-07 2006-09-14 Hakko Co Ltd Medical solution syringe device
CN201179266Y (en) * 2008-04-07 2009-01-14 陈延平 Hydrojet device for uterine cavity detection
CN203777478U (en) * 2014-03-13 2014-08-20 李明 Medicine spraying device for respiratory medicine
CN205729935U (en) * 2015-02-13 2016-11-30 凯西制药公司 For using the conduit of pulmonary surfactant
CN206275904U (en) * 2016-08-29 2017-06-27 高永利 A kind of anesthetic tube
CN208511694U (en) * 2017-09-14 2019-02-19 华润双鹤药业股份有限公司 Pulmonary surfactant drug delivery device

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