CN107449721B - Isolation pool for sheath flow rear pool cleaning device - Google Patents
Isolation pool for sheath flow rear pool cleaning device Download PDFInfo
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- CN107449721B CN107449721B CN201710738917.5A CN201710738917A CN107449721B CN 107449721 B CN107449721 B CN 107449721B CN 201710738917 A CN201710738917 A CN 201710738917A CN 107449721 B CN107449721 B CN 107449721B
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- 238000002955 isolation Methods 0.000 title claims abstract description 186
- 238000004140 cleaning Methods 0.000 title claims abstract description 16
- 239000007788 liquid Substances 0.000 claims abstract description 283
- 230000009919 sequestration Effects 0.000 claims description 15
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- 238000001514 detection method Methods 0.000 abstract description 2
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B9/00—Cleaning hollow articles by methods or apparatus specially adapted thereto
- B08B9/08—Cleaning containers, e.g. tanks
- B08B9/093—Cleaning containers, e.g. tanks by the force of jets or sprays
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
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- Physical Or Chemical Processes And Apparatus (AREA)
- Cleaning By Liquid Or Steam (AREA)
Abstract
The invention relates to an isolation pool for a sheath flow post-pool cleaning device, which comprises a container body, an inner cavity, a liquid inlet and a liquid outlet, wherein a device for controlling the flow rate of liquid is arranged at a position close to the liquid inlet of the isolation pool, the device for controlling the flow rate of liquid protrudes out of the inner wall of the container body or is installed on the inner wall of the container body, and at least one part of the device for controlling the flow rate of liquid is opposite to the liquid inlet of the isolation pool. Be equipped with the device of control liquid velocity of flow in inlet position department or being close to inlet position department, the liquid that flows from the inlet has carried out the deceleration to strikeing before keeping apart the liquid level in pond inner wall or keeping apart the pond effectively, the velocity of flow when making the liquid that adds touch and keep apart pond inner wall or keep apart bottom of the pool liquid surface is less than the velocity of flow when liquid just flows out the inlet, the impact of liquid to keeping apart pond inner wall or keeping apart bottom of the pool liquid surface of adding has been reduced, the probability of gassing has been reduced, the interference of bubble to the counter has been reduced, the accuracy of instrument detection has been improved.
Description
Technical Field
The invention relates to a sheath flow rear pool cleaning device applied to a flow cytometry, in particular to an isolation pool structure for the sheath flow rear pool cleaning device.
Technical Field
Sheath flow post-pool cleaning devices are a commonly used technique in flow hematology analyzers. The sheath flow back pool cleaning device is generally composed of a front pool, a back pool and a counting hole between the front pool and the back pool. Wherein an electrical signal is present between the solutions in the front and rear wells. The particles in the solution pass through the counting holes between the front and rear wells to cause a change in the electrical signal, so that the front and rear wells need to be isolated, usually the rear well.
The mode of air isolation is basically adopted in present technique, namely a back pool isolation pool exists between back pool feed liquor and liquid storage pool, and liquid firstly drips into back pool isolation pool to cause pressure difference, then liquid enters into back pool, flows out to waste liquid isolation pool from the liquid outlet of back pool, and then enters into waste liquid pool. The waste liquid isolation pool is also isolated by air. The rear pool isolation pool is easy to be involved in air to generate bubbles due to high flow velocity during liquid adding, and the bubbles are mixed into the rear pool to interfere the counting value. When liquid enters the waste liquid isolation tank from the liquid storage tank, the liquid level in the waste liquid isolation tank is directly impacted due to the large liquid flow velocity, and the directly impacted liquid is contacted with the bottom liquid to easily generate bubbles.
The current technology basically adopts an air isolation mode. Please refer to chinese patent application publication No. CN102533536a (application No. 201010609840. X). This patent application discloses a counter subassembly, including counter, waste liquid isolation chamber, back sheath isolation chamber and pressure balance pipeline. The counter is provided with a front pool, a rear sheath inlet and a waste liquid outlet, the front pool and the rear pool are communicated through a counting hole, the rear sheath inlet and the waste liquid outlet are communicated with the rear pool, a rear sheath isolation chamber is connected with the rear sheath inlet, a waste liquid isolation chamber is connected with the waste liquid outlet, and the rear sheath isolation chamber is connected with the ambient atmosphere through a gas pipeline. The pressure balance pipeline is connected with the rear sheath isolation chamber and the waste liquid isolation chamber, and a pressure balance controller for controlling the on-off of the pressure balance pipeline is arranged on the pressure balance pipeline. Liquid is dripped into the waste liquid isolation chamber earlier and is aroused pressure differential, then liquid enters into the back pond through back sheath entry, flows out to the waste liquid isolation pond from the waste liquid outlet of back pond again, then gets into the waste liquid pond again. The waste liquid isolation pool is also isolated by air. When liquid is added into the rear pool, air is easily involved into the rear pool due to the large flow velocity of the liquid to generate bubbles, and the bubbles are mixed into the rear pool to interfere the counting value of the counter. In addition, in the above process, due to the large flow rate of the liquid, especially when the added liquid directly impacts the liquid surface in the waste liquid isolation tank, the added liquid directly impacts the liquid at the bottom of the waste liquid isolation tank, and bubbles are very easily generated. In order to solve the technical problem, the chinese patent application publication No. CN102533536a discloses a technical solution: the first liquid adding port is obliquely arranged, so that the liquid is enabled to impact the first side wall of the first tank body at a certain angle in the adding process and then flows into the first tank body along the first side wall, and the possibility that air is involved into the liquid in the liquid adding process is reduced as much as possible.
Another liquid discharge conduit arrangement is disclosed in US5,085,833. In order to avoid the generation of bubbles in the container when liquid is added, the liquid inlet pipe of the pipeline device is partially bent into a U shape in the cavity of the container, and the tail end of the liquid inlet pipe is close to and opposite to the inner wall of the container. When liquid is added, the liquid firstly impacts the inner wall of the container and then flows downwards along the inner wall of the container, so that the added liquid is prevented from directly impacting the liquid level at the bottom of the container, and the generation probability of bubbles is reduced.
Although the above two patent publications avoid the added liquid from directly impacting the liquid level at the bottom of the container, and to some extent, reduce the probability of air bubbles, the limitations are also obvious. For example, the flow rate of the liquid as it impinges on the inner wall of the vessel is substantially the same as the flow rate of the liquid as it leaves the inlet without substantial deceleration. Therefore, the impact force of the introduced liquid against the inner wall of the container is large (the faster the flow rate of the introduced liquid, the larger the impact force). After the added liquid impacts the inner wall of the container, only a few liquids flow downwards along the inner wall of the container as expected by the designer, and most liquids bounce back after contacting the inner wall of the container to form splashes in the container. When the splashed liquid falls into the bottom of the container, the splashed liquid impacts the liquid surface at the bottom of the container, and bubbles affecting the accuracy of counting are easily generated.
In order to overcome the defects of the prior art, the invention provides a brand new technical scheme, and the liquid is subjected to speed reduction treatment after leaving the liquid inlet and before touching the inner wall of the container or the liquid level of the liquid at the bottom of the container, so that the impact force of the added liquid on the inner wall of the container or the liquid level of the liquid at the bottom of the container is reduced, the probability of generating bubbles is greatly reduced, the interference of the bubbles on the counting of the counter is reduced, the counting accuracy of the counter is greatly improved, and the detection accuracy of a biochemical analyzer is greatly improved finally.
Disclosure of Invention
The technical scheme of the invention is as follows: the utility model provides an isolation pool that is used for behind sheath flow pond belt cleaning device, includes the container body, interior cavity, inlet and liquid outlet, its characterized in that: the device for controlling the flow rate of the liquid is arranged at a position near the liquid inlet of the isolation pool, protrudes from the inner wall of the container body or is arranged on the inner wall of the container body, and at least one part of the device for controlling the flow rate of the liquid is opposite to the liquid inlet of the isolation pool.
In the present invention, the phrase "means for controlling the flow rate of the liquid is provided at a position near the liquid inlet of the isolation tank" means that: the linear distance between the liquid inlet and the device for controlling the flow rate of the liquid is smaller than the linear distance between the liquid inlet and the inner wall of the isolation pool which is faced by the liquid inlet.
As a further improvement of the invention, the device for controlling the flow rate of the liquid comprises a stopper which extends from the inner wall of the isolation tank to the inner cavity of the isolation tank and the tail end of the stopper extends to exceed the axis or the central line of the liquid inlet by at least 5mm.
As a further improvement of the invention, the liquid inlet is positioned on the side wall of the isolation pool, and the baffle block comprises an elongated cylindrical structure extending from the top wall of the isolation pool to the inner cavity of the isolation pool.
As a further improvement of the invention, the liquid inlet is positioned on the side wall of the isolation pool, and the baffle block comprises a flat plate structure extending from the top wall of the isolation pool to the inner cavity of the isolation pool.
As a further development of the invention, the stop is perpendicular or inclined with respect to the top wall of the separation tank.
As a further improvement of the invention, the angle between the baffle block and the top wall of the isolation pool is 45 degrees.
As a further improvement of the invention, the liquid inlet is positioned on the top wall of the isolation pool, and the baffle block comprises a structure which extends from the side wall of the isolation pool to the inner cavity of the isolation pool.
As a further improvement of the invention, the liquid inlet is positioned on the top wall of the isolation tank, the device for controlling the flow rate of the liquid comprises a disc-shaped or cone-shaped structure fixed on the inner wall of the isolation tank, and a gap is designed between the inner wall of the isolation tank and the edge of the disc-shaped or cone-shaped structure.
As a further improvement of the invention, the outer circular edge of the disc-shaped or cone-shaped structure is designed with a plurality of notches.
As a further improvement of the invention, the outer circular edge of the disc-shaped or cone-shaped structure is designed with a porous structure or a porous material which allows liquid to pass through.
The other technical scheme of the invention is as follows: provided is a post sheath flow bath cleaning device, comprising: a liquid storage tank, an isolation tank and a counting tank which are connected by pipelines; the counting pool comprises a rear pool, a front pool and a counting hole between the rear pool and the front pool; the isolation pool comprises a liquid inlet connected to the liquid storage pool and a liquid outlet connected to the rear pool; and any of the above-described sequestration tanks and improvements thereto.
The invention also adopts a technical scheme that: provided is a blood cell analyzer, characterized in that: comprises the sheath flow rear pool cleaning device.
Advantageous effects
By the inlet position department at isolation pond or be equipped with the device of control liquid velocity of flow near the inlet position department of isolation pond, liquid to flowing from the inlet has carried out the deceleration to strikeing isolation pond inner wall or keeping apart the liquid level in the pond before effectively, the velocity of flow when making the liquid of adding touch isolation pond inner wall or keeping apart bottom of the pool liquid level is less than the velocity of flow when liquid just flowed the inlet greatly, greatly reduced the impact of liquid of adding to isolation pond inner wall or keeping apart bottom of the pool liquid level, thereby greatly reduced the probability of producing the bubble, the bubble has been reduced to the interference of counter, the accuracy that the instrument detected has been improved greatly.
When the device for controlling the flow rate of the liquid comprises a gradually expanding pipe structure arranged at the liquid inlet, the hole diameter of the gradually expanding pipe structure is gradually increased from one end, connected with the liquid inlet pipeline, of the gradually expanding pipe structure to the end, close to the wall of the isolation tank, of the gradually expanding pipe structure, the flow rate of the added liquid is gradually reduced, and therefore the impact force of the added liquid on the inner wall of the isolation tank or the liquid level at the bottom of the isolation tank is effectively reduced.
When the device of control liquid velocity of flow includes the dog, this dog is extended and at least part with the inlet is relative by the inner wall of isolation pond to isolation pond inner chamber, and the liquid of adding strikes the dog earlier after the outlet, after the buffering of dog, the velocity of flow of liquid obviously reduces, and liquid perhaps touches the inner wall of isolation pond with lower velocity of flow, then smoothly down flows along the inner wall of isolation pond, or is broken up, falls in the liquid of isolation bottom of the pool portion with lower velocity of flow to the impact force of the liquid of adding to isolation pond inner wall or isolation bottom of the pool liquid level has been reduced effectively.
When the liquid inlet is positioned on the side wall of the isolation pool, the added liquid can not directly impact the liquid level at the bottom of the isolation pool after flowing out from the liquid inlet, thereby reducing the probability of generating bubbles.
When the included angle between the side wall where the liquid inlet is located and the horizontal plane is more than or equal to 30 degrees and less than 45 degrees, and more than or equal to 45 degrees and less than or equal to 60 degrees, the added liquid is ejected upwards in an inclined way by an arc line similar to a parabola after flowing out from the liquid inlet, the self-gravity acting force of the liquid can reduce the flow speed of the liquid, and then the liquid smoothly falls on the inner wall where the liquid inlet is located. When the contained angle of that lateral wall and the horizontal plane at inlet place was greater than 60 degrees angles and is less than 90 degrees angles, liquid upwards spout to setting up on the dog of keeping apart the pond inner wall to one side, after the buffering of dog with break up, then slowly the back-shooting at the inner wall at inlet place, the liquid velocity of flow has reduced. When the contained angle of that lateral wall and the horizontal plane at inlet place equals 90 degrees angles, liquid follow the inlet and spout the back along the horizontal direction to the pitch arc of approximate parabola is inclined downwards to the setting on the dog of keeping apart the pond inner wall, through the buffering of dog with break up after, then slowly the back shoot at the inner wall at inlet place, the liquid velocity of flow has reduced. When the contained angle of that lateral wall and the horizontal plane at inlet place was greater than 90 degrees angles and is less than or equal to 120 degrees angles, liquid slant spout downwards to set up on the dog of keeping apart the pond inner wall, after the buffering of dog with break up, then gently the back shoot at the inner wall at inlet place, the liquid velocity of flow has reduced. When the contained angle of that lateral wall and the horizontal plane of inlet place is greater than 120 degrees angle less than or equal to 135 degrees and is greater than 135 degrees angle less than or equal to 150 degrees angles, liquid slant spout downwards to set up on the dog of keeping apart the pond inner wall, through the buffering of dog with break up after, then gently reverse shoot at the inner wall at inlet place, the liquid velocity of flow has reduced.
When the included angle between the plane where the stopper is located and the axis of the liquid inlet is selected from: similar technical effects to those described above can also be obtained when the angle is greater than or equal to 30 degrees and less than 45 degrees, greater than or equal to 45 degrees and less than or equal to 60 degrees, greater than 60 degrees and less than or equal to 90 degrees, greater than 90 degrees and less than or equal to 120 degrees, greater than 120 degrees and less than or equal to 135 degrees, and greater than 135 degrees and less than or equal to 150 degrees. The applicant is not repeated.
When the isolation pool is vertically arranged, the liquid inlet is positioned on the top wall of the isolation pool, the liquid flow velocity control device is connected with the liquid inlet, at least part of liquid flowing out of the liquid inlet flows to the liquid flow velocity control device firstly, and then flows into the cavity of the isolation pool after being diffused by the liquid flow velocity control device, so that the flow velocity of the liquid is also reduced.
In addition, all set up the lateral part at the isolation pond with inlet and liquid outlet, be favorable to reducing the installation space of back pond isolation pond in vertical direction. The pond body slope with isolation pool is settled, is favorable to making liquid assemble in the one corner, even keep good liquid seal under the condition that the isolation bottom has less volumetric solution only, simultaneously, the pond inner wall of slope has better drainage effect to liquid.
Lateral part feed liquor, inlet and liquid outlet all set up the lateral part at the cell body, are favorable to reducing the installation space of back pond isolation pond in vertical direction.
Keep apart the pond slope, make the liquid in the isolation pond assemble the one corner, even when only having less liquid in the isolation pond, also can keep good liquid seal to the liquid outlet, simultaneously, the pool wall of slope has better liquid drainage effect to the probability of gassing has been reduced.
Drawings
FIG. 1 is a schematic diagram of a first embodiment of the present invention.
FIGS. 1A-1C show a first embodiment of the isolation cell of FIG. 1, and FIGS. 1D-1F show a second embodiment of the isolation cell of FIG. 1.
FIG. 2 is a schematic diagram of a second embodiment of the present invention.
FIGS. 2A-2C show a first embodiment of the sequestration tank in FIG. 2, and FIGS. 2D-2F show a second embodiment of the sequestration tank in FIG. 2.
FIG. 3 is a schematic diagram of a third embodiment of the present invention.
FIG. 3A is an enlarged schematic view of the isolation cell of FIG. 3, and FIGS. 3B and 3C are first and second designs of the apparatus of FIG. 3A; fig. 3D-3F show a third and a fourth embodiment of the device according to fig. 3.
FIG. 4 is a schematic diagram of a fourth embodiment of the present invention.
FIGS. 4A-4C are a first design of the isolation cell of FIG. 4, FIGS. 4D-4F are a second design of the isolation cell of FIG. 4, and FIG. 4G is a third design of the isolation cell of FIG. 4.
FIG. 5 is a schematic view of a fifth embodiment of the present invention.
FIGS. 5A-5C show a first embodiment of the isolation tank of FIG. 5, and FIG. 5D shows a second embodiment of the isolation tank of FIG. 5.
Fig. 6A and 6B are schematic diagrams of the first and second designs of the sixth embodiment of the present invention.
Fig. 6C is a partially enlarged schematic view of fig. 6A.
FIGS. 7A and 7B are schematic illustrations of first and second designs of a seventh embodiment of the invention, and FIG. 7C is a partial bottom view of FIG. 7A.
FIGS. 8A to 8G are schematic views showing seven placement positions of the separation cells in the first embodiment of the present invention.
DETAILED DESCRIPTION OF EMBODIMENT (S) OF INVENTION
Example 1
Referring to fig. 1, the sheath flow back pool cleaning apparatus of the present invention comprises: a liquid storage tank 100, an isolation tank 200 and a counting tank 300. Wherein, the counting cell 300 comprises a rear cell 400, a front cell 500 and a counting hole 600 between the rear cell 400 and the front cell 500. The isolation tank 200 comprises a container body 201, a liquid inlet 202 and a liquid outlet 204, wherein the container body 201 comprises a top wall 203, a bottom wall 205 and a side wall 207. The top, bottom and side walls enclose an inner cavity 209 that isolates the tank. The container body 201 may be a cylinder, a cube, a sphere, an ellipsoid, or a combination of a cylinder and a hemisphere or a cone. The inlet 202 of the buffer tank is connected to the liquid reservoir 100 via a pipe 700 (all pipes are collectively referred to as "the same" throughout the text), and the outlet 204 of the buffer tank is connected to the rear tank 400 via a pipe 700. The innovation of the present invention mainly comprises: a) A device 206 for controlling the flow rate of the liquid is connected to the position of the liquid inlet 202 of the isolation pool 200, or a device 206 for controlling the flow rate of the liquid is arranged at a position close to the position of the liquid inlet 202 of the isolation pool 200 (at the moment, at least one part of the device 206 for controlling the flow rate of the liquid is opposite to the liquid inlet 202 of the isolation pool 200); b) The novel structure of the means for controlling the flow rate of liquid 206; c) A novel and novel arrangement of the isolation pool 200; and D) novel placement of the inlet 202 and outlet 204 of the isolation tank 200.
In a first variant of example 1, the separation cell 200 is designed to be placed obliquely, i.e. the axis or centerline of the separation cell 200 is at an angle other than 90 degrees to the horizontal. In a second variant of example 1, the isolation cell 200 is designed to be placed vertically, i.e. the axis or centre line of the isolation cell 200 is at an angle equal to 90 degrees to the horizontal.
Referring to FIGS. 1A-1F, FIG. 1A is a first schematic diagram of an isolation tank 200 of the present invention in a vertical position, and FIGS. 1B and 1C are a right side view and a bottom view of FIG. 1A, respectively; FIG. 1D is a schematic diagram of a second configuration of the isolation tank 200 of the present invention when it is vertically positioned, and FIGS. 1E and 1F are right and bottom views of FIG. 1D, respectively. In a first embodiment, the means 206 for controlling the flow rate of the liquid comprises a stopper extending from an inner wall of the separation chamber towards the inner cavity 209 of the separation chamber (i.e. protruding from the inner wall of the separation chamber) and at least partly opposite the inlet port 202. The invention that the device for controlling the flow rate of the liquid is at least partially opposite to the liquid inlet refers to that: at least a part of the means for controlling the flow rate of the liquid is located close to the inlet 202, so that the orthographic projection of the outer contour of the inlet is wholly or partially located on the means for controlling the flow rate of the liquid, and at least a part of the liquid flowing out of the inlet can impact or flow onto the stopper. In another embodiment, the stopper 206 extends from the interior wall 207 of the sequestration tank to the interior cavity 209 of the sequestration tank such that the end of the stopper 206 is at least 5mm (millimeters, if any) beyond the axis or centerline of the loading port 202. The liquid inlet 202 is located on the side wall 207 of the isolation pool 200. The block 206 comprises an elongated cylindrical structure (as shown in figures 1A-1C and 2D-2F) or an elongated flat plate structure (as shown in figures 1D-1F and 2A-2C) extending from the top wall 203 of the cell 200 to the cavity 209 within the cell.
In example 1, the isolation tank 200 is fed laterally, i.e., the inlet port 202 and the outlet port 204 are both located on the sidewall 207 of the isolation tank 200. The block 206 extends from the top wall 203 of the isolation tank to the inner cavity 209 of the isolation tank and is perpendicular to the top wall 203 of the isolation tank, and at least partially opposite to the liquid inlet of the isolation tank 200. Meanwhile, the isolation tank 200 is vertically or obliquely arranged, so that the liquid in the inner cavity 209 is converged at the bottom of the isolation tank 200 (the liquid inlet 202 is positioned at a higher position than the liquid outlet 204).
Furthermore, in an alternative embodiment, the inlet port 202 is located in the top wall 203 of the isolation chamber, and the stopper 206 is located in the side wall 207 of the isolation chamber, i.e., the stopper 206 comprises a structure extending from the side wall 207 of the isolation chamber to the cavity 209 in the isolation chamber, and at least a portion of the stopper 206 is opposite to the inlet port 202.
The liquid inlet 202 is arranged on the side wall of the isolation pool container body, and can be used for feeding liquid perpendicular to the side wall or obliquely. The liquid outlet 204 may be disposed at the lower portion of the sidewall of the isolation tank container body of the tank body, or at the bottom wall of the isolation tank container body.
The stopper 206 may be integrally formed with the separation tank container body, or may be separately manufactured and then detachably mounted in the separation tank 200.
The vertical length of the stop 206 is less than one half of the height of the separation tank container body, preferably in the range of one fifth to one third. The shortest distance of the stop 206 is such that it blocks the incoming liquid (i.e., the liquid entering the liquid can impact the stop 206). The stopper 206 may be cylindrical or flat. The minimum width of the block 206 is larger than the inner diameter of the liquid inlet, and the maximum width of the block 206 is subject to the condition that no liquid suspension is formed between the block 206 and the side wall of the isolation pool. The hanging liquid refers to liquid drops attached between the stop block and the side wall. Typically the hanging fluid has a diameter of 2mm to 5mm and therefore the minimum clearance between the stop 206 and the side wall of the separation cell is greater than 5mm.
The buffer of the stopper 206 for the rapidly flowing liquid is specifically as follows: after liquid enters from the liquid inlet 202 of the side wall 207 of the isolation tank, firstly, a part of liquid directly impacts the stop block 206, the stop block 206 breaks up the part of liquid, and the broken-up liquid is drained from the tank wall of the isolation tank at a low speed and then falls to the tank bottom of the isolation tank or the liquid level in the isolation tank, or directly falls to the tank bottom of the isolation tank or the liquid level in the isolation tank; secondly, another part of the liquid, under the block of the block 206, slides out from the two sides of the block 206 and directly impacts on the side wall 207 of the isolation tank, and the part of the liquid flows into the bottom of the isolation tank or the liquid level in the isolation tank along the side wall 207 or directly drops to the bottom of the isolation tank or the liquid level in the isolation tank.
After the liquid enters the inner cavity 209 of the isolation tank, the liquid level in the isolation tank rises to generate pressure difference, so that the liquid in the tank flows into the rear tank 400 of the counting tank and then flows into a waste liquid isolation tank (not shown) from a liquid outlet at the upper part of the counting tank 300. When the air pressure in the isolation tank 200 is recovered, the liquid stops flowing, and the air pressure in the isolation tank reaches an equilibrium state. Because the isolation tank is obliquely arranged, the liquid outlet 204 at the lower part of the isolation tank is always below the liquid level, and air cannot enter a pipeline connected with the rear tank 400.
Because the stopper 206 has played the effect of buffering to liquid, reduced the velocity of flow of liquid, consequently, when liquid falls into the bottom of the pool of isolation pond or when keeping apart the liquid level in the pond, reduced the liquid greatly to the bottom of the pool of isolation pond or the impact dynamics of the liquid level in the isolation pond to greatly reduced the probability of being drawn into air and producing the bubble in the isolation pond.
Example 2
Fig. 2 and 2A-2F show a second embodiment of the present invention. The main differences between the second embodiment and the first embodiment are: the angle between the stopper 206 and the top wall 203 of the isolation pool is 45 degrees, that is, the stopper 206 extends from the top wall 203 of the isolation pool to the inner cavity 209 of the isolation pool, and the angle between the stopper 206 and the plane where the top wall 203 of the isolation pool is located is 45 degrees or 135 degrees. The inventor has shown through experiments that the angle between the stopper 206 and the plane of the top wall 203 of the separation tank can also be selected from: the angle is greater than or equal to 30 degrees and less than or equal to 60 degrees, greater than 60 degrees and less than or equal to 90 degrees, equal to 900 degrees, greater than 90 degrees and less than or equal to 120 degrees, and greater than 120 degrees and less than or equal to 150 degrees. Due to the design of the stopper, the included angle between the plane where the stopper is located and the axis of the liquid inlet can also be 45-degree angle or 135-degree angle, or is selected from the following angles: the angle is greater than or equal to 30 degrees and less than or equal to 60 degrees, greater than 60 degrees and less than or equal to 90 degrees, equal to 900 degrees, greater than 90 degrees and less than or equal to 120 degrees, and greater than 120 degrees and less than or equal to 150 degrees.
In embodiment 2, the stopper 206 may have a flat plate-like structure as shown in fig. 2A to 2C. The flat structure enables the block to have a larger area, and has better buffering and drainage effects on liquid impacting on the block.
Example 3
Fig. 3 and 3A-3F illustrate a third embodiment of the present invention. The main differences between the third embodiment and the first embodiment are: a) The isolation pond 200 is vertically arranged (although the isolation pond can be obliquely arranged, the isolation pond is better in effect when the isolation pond is vertically arranged); b) The liquid inlet 202 of the isolation tank is positioned on the top wall 203 of the isolation tank, and the liquid outlet 204 of the isolation tank is positioned on the lower part or the bottom wall 205 of the side wall 207 of the isolation tank; c) The means for controlling the flow rate of the liquid 206 is a disk-like (as shown in fig. 3D) or cone-like structure (as shown in fig. 3A). At this time, the disk-shaped or cone-shaped structure is fixed on the inner wall of the separation tank, and a gap allowing liquid to pass is designed between the edge of the disk-shaped or cone-shaped structure and the inner wall 207 of the separation tank. As shown in FIG. 3B, the edge of the disc or cone structure is designed with a plurality of notches or grooves 208 allowing liquid to pass through. As shown in FIG. 3C, a porous structure allowing liquid to pass through or a circular ring 210 made of porous material (such as sponge ring, rubber ring with holes, ring twisted by porous material such as cloth, etc.) is installed on the outer edge of the disk-shaped or cone-shaped structure. In addition to the notches or grooves 208 in the outer edge region of the disc-like or cone-like structure, a plurality of small holes 213 (as shown in fig. 3E and 3F) may be formed in other regions. It is also possible that there are no notches or grooves in the outer edge area of the disc-like or cone-like structure, while only in other areas there are designed a number of small holes 213 (not shown).
Example 4
Fig. 4 and 4A-4G illustrate a fourth embodiment of the present invention. The main differences between the fourth embodiment and the first embodiment are: a) The isolation pond 200 is vertically arranged (although the isolation pond can be obliquely arranged, the isolation pond is better in effect when the isolation pond is vertically arranged); b) The liquid inlet 202 of the isolation tank is positioned on the top wall 203 of the isolation tank, and the liquid outlet 204 of the isolation tank is positioned on the lower part or the bottom wall 205 of the side wall 207 of the isolation tank; c) The device for controlling the flow rate of the liquid comprises a stop block 206 arranged at the liquid inlet 202, the liquid inlet 202 is connected with the stop block 206, a channel 212 is arranged between the liquid inlet 202 and the stop block 206, the liquid flowing out of the liquid inlet 202 is diffused to the upper surface of the stop block 206 after passing through the channel 212, and falls into the isolation pool after being drained through the upper surface of the stop block 206, so that the flow rate of the liquid is reduced.
As shown in fig. 4A-4C, the stopper 206 is an elongated cylindrical structure disposed substantially parallel to the isolation Chi Debi, and the pipe where the stopper 206 and the liquid inlet 202 are located forms a T-shaped structure. Alternatively, the stop 206 may be a disk-like structure (as shown in FIGS. 4D-4F) or a cone-like structure (as shown in FIG. 4G) placed substantially parallel to the barrier Chi Debi 205. At this time, a disk-like or cone-like structure is fixed to the inner wall 207 of the separation cell, with the center of the cylinder or cone facing the liquid inlet 202. A gap is designed between the edge of the disc-shaped or cone-shaped structure and the inner wall 207 of the isolation pool to allow liquid to pass through (see embodiment 3 of the invention for specific structure).
Example 5
Fig. 5 and 5A-5D show a fifth embodiment of the present invention. The main differences between the fifth embodiment and the first embodiment are: the means for controlling the flow rate of liquid comprises a divergent tube structure 206 arranged at the liquid inlet 202. The diverging tube structure 206 comprises a cavity 215 communicating with the inlet port 202, the inner wall of the cavity 215 having a bore diameter that increases from the end thereof connected to the inlet port 202 to the end thereof remote from the inlet port 202. The diverging tube structure 206 may be conical or trumpet shaped. The pipes of the divergent pipe structure 206 and the liquid inlet 202 are not coaxially installed, that is, the axis or the center line of the divergent pipe structure is neither overlapped nor parallel to the axis or the center line of the channel where the liquid inlet is located, and preferably, the axes or the center lines are mutually crossed or form an acute angle, so that the liquid entering from the liquid inlet pipe 202 can be blocked by the wall surface of the divergent pipe 206 and is in a water storage state, the liquid in the liquid inlet pipe is prevented from directly impacting the liquid level in the isolation tank through the divergent pipe, and the generation probability of bubbles is reduced. The effect of the diverging tube will be better when the axis or centerline of the diverging tube structure 206 is tilted up relative to the horizontal.
The diverging tube structure 206 acts to slow the flow of the liquid, so that the flow of the liquid can be reduced without providing an additional blocking device.
The specific process of the liquid flow rate being reduced by the divergent structure 206 is as follows: liquid entering from the inlet port 202 first impacts the inner wall of the diverging tube structure 206 and then accumulates in the region of greater volume, slowing the flow rate of the liquid during accumulation. When the liquid in the divergent structure 206 is filled and overflows, the overflowing liquid flows into the inner cavity 209 of the separation tank along the inner side wall of the separation tank 200.
Example 6
Fig. 6A-6C illustrate a sixth embodiment of the present invention. The main differences between the sixth embodiment and the first embodiment are: the means for controlling the flow rate of the liquid includes a shower means 206 connected to the inlet port 202. The shower head device 206 is connected to the conduit of the liquid inlet 202 through its opening 220. The showerhead arrangement 206 includes a cavity 218 in communication with the inlet port 202 and at least two showerhead holes 222 communicating the cavity 218 with the isolated well bore 209. The showerhead assembly 206 includes a cylindrical structure having showerhead holes 222 (shown in FIG. 6C) in both the bottom and side walls. In this embodiment, the isolation pond 200 may be placed either vertically (fig. 6A) or obliquely (fig. 6B).
Example 7
Fig. 7A-7C illustrate a seventh embodiment of the present invention. The main differences between the seventh embodiment and the sixth embodiment are: the shower device 206 changes the cylindrical structure into the conical structure, and is provided with the shower holes 224 only on the bottom wall, and the other structures are the same.
In a further improved design, the cavity of the device for controlling the flow rate of the liquid can contain sponge, cotton, filter paper, activated carbon, porous ceramic, silk screen, glass fiber, fabric and other filling materials with porosity allowing liquid permeation.
The arrangement of the isolation ponds included in the present invention is shown in FIGS. 8A-8G. Taking the first embodiment as an example (and the other embodiments can be analogized), the central line 228 of the separation tank or the side wall 207 of the liquid inlet 202 forms an angle equal to about 45 degrees or 135 degrees with the horizontal plane in the three o' clock direction 226, or is selected from: the angle is greater than or equal to 30 degrees and less than or equal to 60 degrees, greater than 60 degrees and less than or equal to 90 degrees, greater than 90 degrees and less than or equal to 120 degrees, and greater than 120 degrees and less than or equal to 150 degrees. When the isolation pool is obliquely placed, liquid slides into the inner cavity of the isolation pool along the inner wall of the isolation pool after being buffered or scattered by the device for controlling the flow rate of the liquid, so that the drainage effect is better, and the probability of generating bubbles is reduced.
For the sake of clarity of the present patent application, the applicant discloses only the differences from the first embodiment in other embodiments, and the descriptions of the differences are not repeated.
In all embodiments of the present invention, the stopper 206 may be made of hard materials such as hard plastic, wood block, bamboo sheet, metal, etc., or soft materials such as rubber, soft plastic, waterproof paper, fiber, etc. When made of soft material, the stopper 206 is preferably longer to provide better liquid buffering effect.
The invention discloses an isolation pool for the sheath flow rear pool cleaning device, a sheath flow rear pool cleaning device comprising the isolation pool, and a blood cell analyzer comprising the sheath flow rear pool cleaning device. Since the main improvement of the blood cell analyzer of the present invention is the isolation chamber for the post sheath flow chamber cleaning device as disclosed in detail above, the other structures are substantially the same as those of the prior art, and thus, the applicant does not need to describe any further.
Although the present patent application discloses the essence of the present invention sufficiently, the inventor cannot describe the content of the present invention in its entirety without details. Any matter that can be made or derived from the disclosure of this patent application without creative effort shall be included in the disclosure of this patent application and shall fall within the scope of protection claimed by this patent application.
Claims (11)
1. The utility model provides an isolation pool for pond belt cleaning device behind sheath flow, includes the container body, interior cavity, inlet and liquid outlet, its characterized in that: the isolation pool is in a flat bottom shape and is obliquely arranged; a device for controlling the flow rate of the liquid is arranged at a position close to the liquid inlet of the isolation pool, protrudes from the inner wall of the container body or is arranged on the inner wall of the container body, and at least one part of the device is opposite to the liquid inlet of the isolation pool; the device for controlling the flow rate of the liquid comprises a stop block or an gradually-expanding pipe structure arranged at the liquid inlet, the gradually-expanding pipe structure comprises a cavity communicated with the liquid inlet, and the aperture of the inner wall of the cavity is gradually increased from one end of the inner wall connected with the liquid inlet to the end of the inner wall far away from the liquid inlet.
2. The sequestration tank of claim 1, wherein: the baffle block extends from the inner wall of the isolation pool to the inner cavity of the isolation pool, and the tail end of the baffle block extends at least 5mm beyond the axis or the central line of the liquid inlet.
3. The sequestration tank of claim 2, wherein: the liquid inlet is positioned on the side wall of the isolation pool, and the baffle block comprises a strip-shaped cylinder structure extending from the top wall of the isolation pool to the inner cavity of the isolation pool.
4. The sequestration tank of claim 2, wherein: the liquid inlet is positioned on the side wall of the isolation pool, and the baffle block comprises a flat plate structure extending from the top wall of the isolation pool to the inner cavity of the isolation pool.
5. The sequestration tank in accordance with claim 3 or 4, characterized in that: the stop block is vertical or inclined relative to the top wall of the isolation pool.
6. The sequestration tank of claim 5, wherein: the included angle of the stop block relative to the top wall of the isolation pool is 45 degrees.
7. The sequestration tank of claim 2, wherein: the liquid inlet is positioned on the top wall of the isolation pool, and the baffle block comprises a structure which extends from the side wall of the isolation pool to the inner cavity of the isolation pool.
8. The sequestration tank of claim 1, wherein: the liquid inlet is positioned on the top wall of the isolation pool, the device for controlling the liquid flow rate comprises a disc-shaped or cone-shaped structure fixed on the inner wall of the isolation pool, and a gap is designed between the inner wall of the isolation pool and the edge of the disc-shaped or cone-shaped structure.
9. The sequestration tank of claim 8, wherein: the outer circular edge of the disc-shaped or cone-shaped structure is provided with a plurality of notches.
10. The sequestration tank of claim 8, wherein: the outer circular edge of the disc-shaped or cone-shaped structure is designed with a porous structure or a porous material which allows liquid to pass through.
11. The sequestration tank according to one of claims 8-10, characterized in that: and a plurality of small holes are designed in other areas except the outer edge area of the disc-shaped or cone-shaped structure.
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CN202310063706.1A CN117531796A (en) | 2017-08-09 | 2017-08-25 | Isolation tank for sheath flow post-tank cleaning device, sheath flow post-tank cleaning device and blood cell analyzer |
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CN201710677601X | 2017-08-09 |
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CN202310063706.1A Division CN117531796A (en) | 2017-08-09 | 2017-08-25 | Isolation tank for sheath flow post-tank cleaning device, sheath flow post-tank cleaning device and blood cell analyzer |
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CN202310063706.1A Pending CN117531796A (en) | 2017-08-09 | 2017-08-25 | Isolation tank for sheath flow post-tank cleaning device, sheath flow post-tank cleaning device and blood cell analyzer |
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WO2019028940A1 (en) * | 2017-08-09 | 2019-02-14 | 利多(香港)有限公司 | Sheath flow impedance counting device and flow cytometry analyzer comprising device |
CN108941076B (en) * | 2018-06-29 | 2020-11-03 | 迈克医疗电子有限公司 | Apparatus and method for cleaning a biological particle counting device |
JP7267088B2 (en) * | 2019-05-10 | 2023-05-01 | 東京エレクトロン株式会社 | Tanks, substrate processing equipment, and methods of using tanks |
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CN117531796A (en) | 2024-02-09 |
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