CN107449558B - Infusion bottle sealing leakage detection device and leakage detection method thereof - Google Patents

Infusion bottle sealing leakage detection device and leakage detection method thereof Download PDF

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Publication number
CN107449558B
CN107449558B CN201710501875.3A CN201710501875A CN107449558B CN 107449558 B CN107449558 B CN 107449558B CN 201710501875 A CN201710501875 A CN 201710501875A CN 107449558 B CN107449558 B CN 107449558B
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China
Prior art keywords
infusion bottle
bottleneck
vacuum
clamp arm
vacuum tank
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CN201710501875.3A
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Chinese (zh)
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CN107449558A (en
Inventor
柏仁国
刘文军
罗成鑫
刘思川
谭鸿波
葛均友
谢彬
须明君
舒荣华
王昌斌
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Sichuan Kelun Pharmaceutical Co Ltd
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Sichuan Kelun Pharmaceutical Co Ltd
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Priority to CN201710501875.3A priority Critical patent/CN107449558B/en
Publication of CN107449558A publication Critical patent/CN107449558A/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01MTESTING STATIC OR DYNAMIC BALANCE OF MACHINES OR STRUCTURES; TESTING OF STRUCTURES OR APPARATUS, NOT OTHERWISE PROVIDED FOR
    • G01M3/00Investigating fluid-tightness of structures
    • G01M3/02Investigating fluid-tightness of structures by using fluid or vacuum
    • G01M3/04Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point
    • G01M3/06Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point by observing bubbles in a liquid pool
    • G01M3/10Investigating fluid-tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point by observing bubbles in a liquid pool for containers, e.g. radiators

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  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Examining Or Testing Airtightness (AREA)

Abstract

The invention discloses a leakage detecting device for the sealing performance of an infusion bottle and a leakage detecting method thereof, and the leakage detecting device comprises a vacuum tank, an infusion bottle fixing frame, a vacuumizing device and a control system, wherein the vacuum tank is provided with a vacuum chamber with an upward opening, purified water is contained in the vacuum chamber of the vacuum tank, the infusion bottle fixing frame placed in the purified water is placed in the vacuum chamber of the vacuum tank, the vacuumizing device is communicated with the top of the vacuum chamber of the vacuum tank, the vacuumizing device is in electric communication connection with the control system, and the upper opening of the vacuum chamber of the vacuum tank is sealed by a sealing top plate; the infusion bottle mount includes supporting disk, infusion bottle bottleneck anchor clamps and bracing piece, is equipped with a plurality of infusion bottle bottleneck anchor clamps on the supporting disk. The infusion bottle fixing frame holding the infusion bottle is placed in the vacuum tank storing purified water, and the purpose of quick leak detection can be realized by observing whether bubbles are emitted at the bottle mouth of each infusion bottle.

Description

Infusion bottle sealability leakage detection apparatus and its leak hunting method
Technical field
The present invention relates to infusion bottle leak detection technical field more particularly to a kind of infusion bottle sealability leakage detection apparatus and its leak detections Method.
Background technique
Infusion bottle is the container of liquid drug, and after the liquid drug into infusion bottle, certain infusion bottles can have leakproofness Insufficient problem, this just needs to hunt leak to being sealed property of infusion bottle.Currently, to the mode that infusion bottle is hunted leak, often all It is then to see whether there is medical fluid exudation at infusion bottle bottleneck or bottle cap by manual compression infusion bottle, leak detection operation is not only time-consuming Arduously, and precision of detecting leak gas is not also high.If infusion bottle leakproofness is bad, it is easy for occurring the medical fluid in infusion bottle by the external world The phenomenon that air pollution.
Summary of the invention
Place in view of the shortcomings of the prior art, the purpose of the present invention is to provide at a kind of swift to operate, mass The infusion bottle sealability leakage detection apparatus of reason can be adapted for the leak detection operation of various infusion bottle air-tightness requirements.
The purpose of the invention is achieved by the following technical solution:
A kind of infusion bottle sealability leakage detection apparatus, including vacuum tank, infusion bottle fixed frame, vaccum-pumping equipment and control system System, the vacuum tank are provided with opening up vacuum chamber, and purified water is loaded in the vacuum chamber of the vacuum tank, described true The infusion bottle fixed frame being placed in purified water, the vacuum of the vaccum-pumping equipment and vacuum tank are placed in the vacuum chamber of slack tank Chamber roof is connected, and the vaccum-pumping equipment is connect with control system telecommunication, and the control system is vacuumized for controlling Equipment is to the vacuum chamber vacuum pumping of vacuum tank and the setting of suction, the top of the vacuum chamber of the vacuum tank Opening passes through sealing top plate closing;The infusion bottle fixed frame includes support plate, infusion bottle bottleneck fixture and support rod, the branch Support plate be equipped with several infusion bottle bottleneck fixtures, the infusion bottle bottleneck fixture include bottleneck clamp arm A and with A pairs of bottleneck clamp arm Be provided with several arc clamp ports A on bottleneck the clamp arm B, the bottleneck clamp arm A that should be arranged, be provided on the bottleneck clamp arm B with Arc clamp port A quantity, the corresponding arc clamp port B in position, the arc clamp port A and corresponding arc clamp port B Collectively form bottleneck clamp port;Described one end bottleneck clamp arm A respectively corresponds with the one end bottleneck clamp arm B and is connected to by bolted splice In support plate, it is equipped between the bottleneck clamp arm A other end and the bottleneck clamp arm B other end and opens end portion connection block, the unlatching End portion connection block passes through that bolt and the bottleneck clamp arm A other end, the bottleneck clamp arm B other end is detachable is fixedly connected respectively;It is described Each bottleneck clamp port that infusion bottle bottleneck fixture is corresponded in support plate is provided with bottleneck through-hole, is connected at least in the support plate Three support rods.
In order to the present invention is better achieved, several threaded holes are provided on the bottleneck clamp arm A, bottleneck clamp arm B, it is described Bolt is fitted in the threaded hole of bottleneck clamp arm A, the bolt that bottleneck clamp arm A is corresponded in the support plate, which is equipped with, to be threadedly coupled Hole;It is fitted with bolt in the threaded hole of the bottleneck clamp arm B, the bolt that bottleneck clamp arm B is corresponded in the support plate is equipped with Threaded connection hole.
Further preferred technical solution is: there are four support rod, the support rod includes branch for connection in the support plate Pedestal, vertical bar and fixture nut are supportted, the vertical bar is fixedly connected at the top of support base, and the vertical bar passes through fixture nut and branch Support plate is connected and fixed.
Preferably, the support plate is manufactured by transparent glass or transparent plastic.
A kind of infusion bottle sealability leak hunting method, method are as follows:
A, each infusion bottle is clamped in each bottleneck clamp port on the infusion bottle bottleneck fixture of infusion bottle fixed frame, So that the infusion bottle bottleneck of infusion bottle is placed in bottleneck clamp port, then by opening end portion connection block, bolt for each infusion The infusion bottle bottleneck of bottle is securely held in corresponding bottleneck clamp port;
B, infusion bottle fixed frame and infusion bottle are placed in the vacuum chamber of vacuum tank, the purified water of vacuum chamber is complete Infusion bottle fixed frame and infusion bottle are flooded in all standing;
C, sealing top plate closing cap is opened by control system and is taken out together on the upper opening of the vacuum chamber of vacuum tank Simultaneously suction is arranged in vacuum equipment, and vaccum-pumping equipment starts and the vacuum chamber of vacuum tank is pumped into the vacuum of corresponding vacuum degree Environment;
D, observe whether the infusion bottle bottleneck of each infusion bottle or the purified water at bottle cap have continuous air bubbles generation, if there is Continuous air bubbles generate, then judging the infusion bottle, there are leakage defects;If generated without continuous air bubbles, the infusion bottle is judged not There are leakage defects.
Preferably, the water surface elevation of purified water is than infusion bottle fixed frame, infusion bottle in vacuum chamber in the step B At least high 25mm of whole height;In the step A, clamping the infusion bottle quantity being placed in infusion bottle fixed frame every time is not surpass Cross 10.
Preferably, suction set by vaccum-pumping equipment is -50KPa, the vacuum chamber of vacuum tank in the step C Room can be maintained at -30KPa~-50KPa at least two minutes after sealing top plate closing.
The present invention compared with the prior art, have the following advantages that and the utility model has the advantages that
The present invention provides a kind of leakage detection apparatus swift to operate, mass processing for the leak detection of infusion bottle air-tightness, can be with Leak detection suitable for various infusion bottle air-tightness requirements operates;Concrete principle is: the infusion bottle that clamping is equipped with infusion bottle is consolidated Surely it is placed in the vacuum tank for storing purified water, whether observe bubbling at each infusion bottle mouth can realize quick inspection The purpose of leakage.
Detailed description of the invention
Fig. 1 is the structural schematic diagram that the present invention uses the first infusion bottle fixed frame;
Fig. 2 is the structural schematic diagram that the present invention uses second of infusion bottle fixed frame;
Fig. 3 is the structural schematic diagram of the first infusion bottle fixed frame in Fig. 1.
Wherein, title corresponding to the appended drawing reference in attached drawing are as follows:
1- vacuum tank, 11- vacuum chamber, 12- seal top plate, 13- purified water, 2- infusion bottle, 21- infusion bottle bottle Neck, 3- infusion bottle fixed frame, 4- support plate, 10- bottleneck clamp port, 5- bottleneck clamp arm A, 51- arc clamp port A, 6- Bottleneck clamp arm B, 61- arc clamp port B, 7- unlatching end portion connection block, 8- threaded hole, 9- support rod, 91- support base, 92- vertical bar, 93- fixture nut.
Specific embodiment
The present invention is described in further detail below with reference to embodiment:
Embodiment
As shown in FIG. 1 to 3, a kind of infusion bottle sealability leakage detection apparatus, including vacuum tank 1, infusion bottle fixed frame 3, pumping Vacuum equipment and control system, vacuum tank 1 are provided with opening up vacuum chamber 11, contain in the vacuum chamber 11 of vacuum tank 1 There is purified water 13, the infusion bottle fixed frame 3 being placed in purified water 13 is placed in the vacuum chamber 11 of vacuum tank 1, vacuumizes and sets It is connected at the top of the standby vacuum chamber 11 with vacuum tank 1, vaccum-pumping equipment is connect with control system telecommunication, and control system is used for Control vacuum chamber 11 vacuum pumping and the setting of suction of the vaccum-pumping equipment to vacuum tank 1, the vacuum of vacuum tank 1 The upper opening of chamber 11 is closed by sealing top plate 12.
As shown in figure 3, infusion bottle fixed frame 3 includes support plate 4, infusion bottle bottleneck fixture and support rod 9, the present embodiment is excellent The support plate 4 of choosing is manufactured by transparent glass or transparent plastic.Support plate 4 is equipped with several infusion bottle bottleneck fixtures, infusion bottle Bottleneck fixture includes the bottleneck clamp arm A5 and bottleneck clamp arm B6 being correspondingly arranged with bottleneck clamp arm A5, is provided on bottleneck clamp arm A5 several Arc clamp port corresponding with arc clamp port A51 quantity, position is provided on a arc clamp port A51, bottleneck clamp arm B6 B61, arc clamp port A51 and corresponding arc clamp port B61 collectively form bottleneck clamp port 10.Bottleneck one end clamp arm A5 with The one end bottleneck clamp arm B6 is respectively corresponded to be connected in support plate 4 by bolted splice, the bottleneck clamp arm A5 other end and bottleneck clamp arm It is equipped between the B6 other end and opens end portion connection block 7, it is another by bolt and bottleneck clamp arm A5 respectively to open end portion connection block 7 End, the bottleneck clamp arm B6 other end is detachable is fixedly connected.Each bottleneck clamping of infusion bottle bottleneck fixture is corresponded in support plate 4 Mouth 10 is provided with bottleneck through-hole, and at least three support rods 9 are connected in support plate 1.
As shown in figure 3, being provided with several threaded holes 8, the screw thread of bottleneck clamp arm A5 on bottleneck clamp arm A5, bottleneck clamp arm B6 Bolt is fitted in hole 8, the bolt that bottleneck clamp arm A5 is corresponded in support plate 4 is equipped with threaded connection hole;Bottleneck clamp arm B6's Bolt is fitted in threaded hole 8, the bolt that bottleneck clamp arm B6 is corresponded in support plate 4 is equipped with threaded connection hole.
As shown in figure 3, there are four support rod 9, support rod 9 includes support base 91, vertical bar 92 and consolidates for connection in support plate 4 Determine nut 93, vertical bar 92 is fixedly connected on 91 top of support base, and vertical bar 92 connect by fixture nut 93 with support plate 4 solid It is fixed.
A kind of infusion bottle sealability leak hunting method, method are as follows:
A, each infusion is clamped in each bottleneck clamp port 10 on the infusion bottle bottleneck fixture of infusion bottle fixed frame 3 Bottle 2, so that the infusion bottle bottleneck 21 of infusion bottle 2 is placed in bottleneck clamp port 10, then by opening end portion connection block 7, bolt The infusion bottle bottleneck 21 of each infusion bottle 2 is securely held in corresponding bottleneck clamp port 10;
B, infusion bottle fixed frame 3 and infusion bottle 2 are placed in the vacuum chamber 11 of vacuum tank 1, vacuum chamber 11 Purified water 13, which is completely covered, floods infusion bottle fixed frame 3 and infusion bottle 2;As shown in Figure 1 and Figure 2, purified water in vacuum chamber 11 13 water surface elevation is 25mm at least higher than infusion bottle fixed frame 3,2 whole height of infusion bottle;It is solid to be placed in infusion bottle for clamping every time Determining 2 quantity of infusion bottle in frame 3 is no more than 10.
C, sealing 12 closing cap of top plate is passed through into control system together on the upper opening of the vacuum chamber 11 of vacuum tank 1 It opens vaccum-pumping equipment and suction is set, the vacuum chamber of vacuum tank 1 11 is simultaneously pumped into corresponding true by vaccum-pumping equipment starting The vacuum environment of reciprocal of duty cycle;Suction set by vaccum-pumping equipment is -50KPa, the vacuum chamber 11 of vacuum tank 1 in step C - 30KPa~-50KPa can be maintained at least two minutes after sealing top plate 12 is closed.
D, observe whether the infusion bottle bottleneck 21 of each infusion bottle 2 or the purified water 13 at bottle cap have continuous air bubbles generation, If there is continuous air bubbles generate, then judge that there are leakage defects for the infusion bottle 2;If generated without continuous air bubbles, judgement should Leakage defect is not present in infusion bottle 2.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within mind and principle.

Claims (7)

1. a kind of infusion bottle sealability leakage detection apparatus, it is characterised in that: including vacuum tank (1), infusion bottle fixed frame (3), take out very Null device and control system, the vacuum tank (1) are provided with opening up vacuum chamber (11), the vacuum of the vacuum tank (1) It is loaded in chamber (11) purified water (13), is placed in the vacuum chamber (11) of the vacuum tank (1) and is placed in purified water (13) In infusion bottle fixed frame (3), be connected at the top of the vacuum chamber (11) of the vaccum-pumping equipment and vacuum tank (1), the pumping Vacuum equipment is connect with control system telecommunication, and the control system is for controlling vaccum-pumping equipment to the vacuum of vacuum tank (1) The upper opening of chamber (11) vacuum pumping and the setting of suction, the vacuum chamber (11) of the vacuum tank (1) is logical The overstocked plate that binds (12) closing;The infusion bottle fixed frame (3) includes support plate (4), infusion bottle bottleneck fixture and support rod (9), the support plate (4) is equipped with several infusion bottle bottleneck fixtures, and the infusion bottle bottleneck fixture includes bottleneck clamp arm A (5) and with bottleneck clamp arm A (5) the bottleneck clamp arm B (6) being correspondingly arranged is provided with several arcs folder on the bottleneck clamp arm A (5) It holds a mouthful A (51), arc clamp port B corresponding with arc clamp port A (51) quantity, position is provided on the bottleneck clamp arm B (6) (61), the arc clamp port A (51) and corresponding arc clamp port B (61) collectively form bottleneck clamp port (10);It is described (5) one end bottleneck clamp arm A and bottleneck clamp arm B (6) one end are respectively corresponded to be connected on support plate (4) by bolted splice, described It is equipped between bottleneck clamp arm A (5) other end and bottleneck clamp arm B (6) other end and opens end portion connection block (7), the unlatching end Link block (7) respectively by bolt and bottleneck clamp arm A (5) other end, bottleneck clamp arm B (6) other end is detachable is fixedly connected; Each bottleneck clamp port (10) that infusion bottle bottleneck fixture is corresponded on the support plate (4) is provided with bottleneck through-hole, the support plate (4) at least three support rods (9) are connected on.
2. infusion bottle sealability leakage detection apparatus described in accordance with the claim 1, it is characterised in that: the bottleneck clamp arm A (5), bottle It is provided with several threaded holes (8) on neck clip arm B (6), is fitted with spiral shell in the threaded hole (8) of the bottleneck clamp arm A (5) Bolt, the bolt that bottleneck clamp arm A (5) is corresponded on the support plate (4) are equipped with threaded connection hole;The screw thread of the bottleneck clamp arm B (6) Bolt is fitted in hole (8), the bolt that bottleneck clamp arm B (6) is corresponded on the support plate (4) is equipped with threaded connection hole.
3. infusion bottle sealability leakage detection apparatus according to claim 1 or 2, it is characterised in that: connect on the support plate (4) It connects there are four support rod (9), the support rod (9) includes support base (91), vertical bar (92) and fixture nut (93), described to erect Bar (92) is fixedly connected at the top of support base (91), and the vertical bar (92) is connect by fixture nut (93) with support plate (4) It is fixed.
4. infusion bottle sealability leakage detection apparatus described in accordance with the claim 1, it is characterised in that: the support plate (4) is by transparent Glass or transparent plastic manufacture.
5. according to the leak hunting method of the described in any item infusion bottle sealability leakage detection apparatus of claim 1-4, it is characterised in that: its Method is as follows:
A, each infusion is clamped in each bottleneck clamp port (10) on the infusion bottle bottleneck fixture of infusion bottle fixed frame (3) Bottle (2), so that the infusion bottle bottleneck (21) of infusion bottle (2) is placed in bottleneck clamp port (10), then by opening end connection The infusion bottle bottleneck (21) of each infusion bottle (2) is securely held in corresponding bottleneck clamp port (10) by block (7), bolt;
B, infusion bottle fixed frame (3) and infusion bottle (2) are placed in the vacuum chamber (11) of vacuum tank (1), vacuum chamber (11) purified water (13), which is completely covered, floods infusion bottle fixed frame (3) and infusion bottle (2);
C, top plate (12) closing cap will be sealed together on the upper opening of the vacuum chamber (11) of vacuum tank (1), pass through and control system System opens vaccum-pumping equipment and suction is arranged, and vaccum-pumping equipment starts and is pumped into the vacuum chamber of vacuum tank (1) (11) The vacuum environment of corresponding vacuum degree;
D, observe whether the infusion bottle bottleneck (21) of each infusion bottle (2) or the purified water (13) at bottle cap have continuous air bubbles production It is raw, if there is continuous air bubbles generate, then judge that there are leakage defects for the infusion bottle (2);If generated without continuous air bubbles, sentence Breaking, there is no leakage defects for the infusion bottle (2).
6. the leak hunting method for bottle sealability leakage detection apparatus of being infused according to claim 5, it is characterised in that: the step B In, the water surface elevation of purified water (13) is at least than infusion bottle fixed frame (3), infusion bottle (2) whole height in vacuum chamber (11) High 25mm;In the step A, clamping infusion bottle (2) quantity being placed in infusion bottle fixed frame (3) every time is no more than 10 It is a.
7. the leak hunting method for bottle sealability leakage detection apparatus of being infused according to claim 5, it is characterised in that: the step C Suction set by middle vaccum-pumping equipment is -50KPa, and the vacuum chamber (11) of vacuum tank (1) is sealed in sealing top plate (12) - 30KPa~-50KPa can be maintained at least two minutes after closing.
CN201710501875.3A 2017-06-27 2017-06-27 Infusion bottle sealing leakage detection device and leakage detection method thereof Active CN107449558B (en)

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CN201710501875.3A CN107449558B (en) 2017-06-27 2017-06-27 Infusion bottle sealing leakage detection device and leakage detection method thereof

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Application Number Priority Date Filing Date Title
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CN107449558B true CN107449558B (en) 2019-04-23

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109186874A (en) * 2018-08-16 2019-01-11 湖南立方新能源科技有限责任公司 Quick-speed leak detection method
CN115352028B (en) * 2022-08-18 2024-03-26 山东宝乐多生物科技有限公司 Large infusion plastic bottle blow molding post-treatment device

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Publication number Priority date Publication date Assignee Title
CN101430297A (en) * 2008-12-18 2009-05-13 中国大冢制药有限公司 Electrical conductance type plastic infusion bottle leak detection machine
CN102243131A (en) * 2010-06-09 2011-11-16 刘水 High-voltage discharge leak detector with infusion bottle in inverted vertical mode
CN203203756U (en) * 2013-04-16 2013-09-18 湖南正中制药机械有限公司 Turnover bottle rotating mechanism of large-volume-parenteral (LVP) transfusion leakage detection equipment
CN204188357U (en) * 2014-11-27 2015-03-04 四川科伦药业股份有限公司 Novel horizontal PP infusion bottle leak hunting device
CN204188344U (en) * 2014-11-27 2015-03-04 四川科伦药业股份有限公司 Device for detecting air tightness of PP (polypropylene) infusion bottle
CN204228366U (en) * 2014-11-27 2015-03-25 四川科伦药业股份有限公司 PP infusion bottle leak hunting device
CN104865014A (en) * 2015-05-11 2015-08-26 北京石油化工学院 Medical plastic infusion bottle batch leak-detection device
CN205642751U (en) * 2016-05-26 2016-10-12 白玲玲 PP infusion bottle gas tightness detection device

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101430297A (en) * 2008-12-18 2009-05-13 中国大冢制药有限公司 Electrical conductance type plastic infusion bottle leak detection machine
CN102243131A (en) * 2010-06-09 2011-11-16 刘水 High-voltage discharge leak detector with infusion bottle in inverted vertical mode
CN203203756U (en) * 2013-04-16 2013-09-18 湖南正中制药机械有限公司 Turnover bottle rotating mechanism of large-volume-parenteral (LVP) transfusion leakage detection equipment
CN204188357U (en) * 2014-11-27 2015-03-04 四川科伦药业股份有限公司 Novel horizontal PP infusion bottle leak hunting device
CN204188344U (en) * 2014-11-27 2015-03-04 四川科伦药业股份有限公司 Device for detecting air tightness of PP (polypropylene) infusion bottle
CN204228366U (en) * 2014-11-27 2015-03-25 四川科伦药业股份有限公司 PP infusion bottle leak hunting device
CN104865014A (en) * 2015-05-11 2015-08-26 北京石油化工学院 Medical plastic infusion bottle batch leak-detection device
CN205642751U (en) * 2016-05-26 2016-10-12 白玲玲 PP infusion bottle gas tightness detection device

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