CN107440816A

CN107440816A - Flexible support graft

Info

Publication number: CN107440816A
Application number: CN201710361080.7A
Authority: CN
Inventors: 彼得·菲利普斯; 朱利安·埃利斯; 艾伦·麦克劳德; 加伊·比顿; 彼得·布彻
Original assignee: Lombard Medical Ltd
Current assignee: Lombard Medical Ltd
Priority date: 2017-05-19
Filing date: 2017-05-19
Publication date: 2017-12-08

Abstract

A kind of flexible support graft, flexible graft material including form of tubes, it is attached to the thread reinforcing material of the graft material, the pipe is with the longitudinal axis and with first end and the second end, wherein described material forms a series of along the longitudinally spaced annular cranse opened of the pipe, each cranse is combined together by connecting some, wherein described stent graft is included in the end cranse of at least one reinforcing material at the first end of the pipe, and wherein, after the implantation, the end cranse has the form for the closed curve for surrounding the imaginary plane perpendicular to the longitudinal axis, wherein described curve has two peaks in the side of the plane and two minimum points in the opposite side of the plane.

Description

Flexible support-graft

Technical field

The present invention relates to flexible support-graft, the flexible support-graft can be used to treat with technology in transit chamber Such as endaortic aneurysm, the intracavitary technology are minimally invasive and therefore can be used in that many ages are too big or the great void is weak So as to not be amenable on the patient of routine operation.

Background technology

Conventional vascular graft is generally made up of fabric or polymer pipe, and the fabric or polymer pipe are in open big hand It is implanted in art operation in patient.The graft being implanted into transit chamber (i.e. from intravascular) is by the transplanting with holder combination Thing forms.

In addition, one of existing subject matter of blood vessel graft for intracavity operation is, due to actively The bending of the distortion typically encountered between the sustainer and common iliac artery of the patient of arteries and veins knurl, existing gillies' graft are present at least partly The trend collapsed.Because when the pipe because appointing when watching reason bending, the external diameter of bending is and curved necessarily than interior path length Excessive graft material kink on bent internal diameter enters in inner chamber, thus makes inner chamber constriction or even makes its closure completely.This Individual problem is also appeared in for repairing in such as blood vessel graft of rouge artery, and its reason is to be applied to rouge artery during going down on one's knees Extreme bending motion.

In addition, once graft is incorporated into artery by surgeon and is positioned at correct opening position, it is necessary to Ensure that it is securely held on such opening position.

The combination of support of some devices currently in use based on support or with graft, support is relative stiffness Cylindrical structure, it has the imperfect surface that is formed by zigzag silk thread or wire netting.This generates firm implant, A kind of but implant of relative inflexibility.The common complication of arterial disease is the blood vessel that high distortion occurs, very difficult So that substantially rigid stent-grafts pass through the blood vessel of the high distortion.

The sacculus that some stent-grafts need to make them internal, which expands, causes graft expansion to be arranged on blood vessel It is interior, although self expandable design is more common.

During preforming support is attached into graft, existing apparatus is usually directed to around support and is attached To the more independent sutures of graft.These sutures must use hand to be attached with costly and time-consuming process.

Another problem for coming from the current design of most of bracket component be difficult to design can such as sustainer- The bifurcated graft that common iliac artery crotch uses.

The present invention seeks the method for providing graft as improved flexible support-graft and preparation.

The content of the invention

According to the first aspect of the invention, there is provided flexible support-graft, it includes the flexible graft of form of tubes Material, the pipe is around the longitudinal axis and has first end and the second end；It is attached to the thread enhancing of the graft material Material, wherein the material forms and a series of passes through multiple connecting portions along the longitudinally spaced annular cranse opened of the pipe, each cranse Divide and be combined together, wherein the stent-grafts are included at least one strengthening material at the first end of the pipe The end cranse of material, and wherein, the end cranse is once implanted just to have and put down around the imagination perpendicular to the longitudinal axis The form of the closed curve in face, wherein the curve has in two peaks of the side of the plane and in the plane Two minimum points of opposite side.(the applicant is referred to as " halO Stent Technology to the configuration of end cranse^TM") technology Advantage is：Compared with conventional stent designs, it allows stent-grafts to have flexibility, to match the dissection knot in hub angle Structure.In addition, ring body portion and spiral limb structure are designed to maintain the patency in the anatomical structure of distortion, and circular design is realized Impayable flexibility, while maintain its intracavitary size (or even under extreme angle).

The stent-grafts of the present invention still very can be conformal, is designed to be suitable to change over time change dissection knot Structure and adaptation pulsating force.Unique fish mouth design contributes to the preferable sealing when changing neck form.

In preferred embodiments, the stent-grafts include the other 2-4 first ends close to the pipe The cranse having with the end cranse identical configuration in portion.This provides stabilization at the first end of stent-grafts Seal area.

The stent-grafts can have the 1-8 barbs close to the first end of the pipe, but preferably have Four or eight barbs, the barb can position close to the end cranse.In preferred embodiments, the barb is tight The point location between the highs and lows on the adjacent end cranse.In use, this can cause outer Section doctor can be implanted into stent-grafts in abdominal artery, wherein the first end of the stent-grafts moves close to kidney Arteries and veins, and the minimum point that the first end is located so that on the cranse of end is in below the arteria renalis, and barb is implanted in abdomen So that support-implant be secured in position in the wall of portion's artery.

Preferably, stent-grafts include the first end between the pipe in the flexible graft material Hole between the second end, the hole are used for another flexible support-graft for receiving form of tubes.This can be have with Flexible support-graft of identical common version as defined above.So, in use, the first end of stent-grafts Portion is close to being implanted at the arteria renalis, and the second end of stent-grafts is implanted in one of common iliac artery, another branch Frame-graft is implanted in another common iliac artery and the first support-graft is connected at the hole.

Brief description of the drawings

Various embodiments of the present invention are only described below as embodiment referring to the drawings, in the accompanying drawings：

Fig. 1 shows the schematic illustration of flexible support-graft according to teaching herein.

Embodiment

Fig. 1 is gone to, this illustrates the schematic wire frame figure of the support according to the present invention, for the sake of clarity without aobvious Show flexible graft material.

Support 10 is formed by the multiple annular cranses 11 being combined together by multiple coupling parts 12.The big end of support 10 Portion 20 is formed by four annular end cranses, and these annular end cranses are formed with so-called " fish mouth " configuration, relative to The imaginary plane of the longitudinal axis of support has two peaks 22 and two minimum points 21 at big end 20.Four 2 forks fall Hook 23 is attached to end cranse, although only show two of which in Fig. 1.

Support 10 be terminate at small end 30 in the form of silk thread is the pipe of framework, in Fig. 1 with modularization side limb 40 Combination display, the modularization side limb 40 are attached to support 10 at midpoint 45.

In use, support 10 is attached to flexible graft material (not shown) and is compressed in delivery catheter certainly And it is delivered to aneurysmal position (such as in abdominal artery) via the otch in the femoral artery of patient in intracavity operation.Branch Frame-graft delivers in the case of not attachment side limb 40, and first by the way that barb 23 is embedded in big end in arterial wall 20 implantation, then deploy stent-grafts, small end 30 are implanted in common iliac artery.Then side limb 40 is delivered to another Common iliac artery is simultaneously attached to stent-grafts at midpoint 45.

All optional and preferred feature and remodeling of described embodiment and dependent claims can be in this culture and education Used in all aspects for the invention led.In addition, the single feature of dependent claims, and all of the embodiment Choosing can be combined with each other and can be exchanged with each other with preferred feature and remodeling.

Claims

1. a kind of flexible support-graft, including

The flexible graft material of form of tubes, the pipe with the longitudinal axis and with first end and the second end,

Be attached to the thread reinforcing material of the graft material, wherein the material formed it is a series of longitudinally spaced along the pipe The annular cranse opened, each cranse are combined together by multiple coupling parts,

Wherein described stent-grafts are included in the end hoop of at least one reinforcing material at the first end of the pipe Circle, and wherein, in implantation, the end cranse has the closed curve around the imaginary plane perpendicular to the longitudinal axis Form, wherein the curve has two peaks in the side of the plane and two in the opposite side of the plane most Low spot.

2. flexible support-graft as claimed in claim 1, including the individual first ends close to the pipe of other 2-4 There is cranse with the end cranse identical configuration.

3. flexible support-graft as claimed in claim 1 or 2, including the individual first ends close to the pipe of 1-8 Barb.

4. flexible support-graft as claimed in claim 1 or 2, including 4 falling close to the first end of the pipe Hook.

5. flexible support-graft as described in claim 3 or 4, wherein the barb positions close to the end cranse.

6. flexible support-graft as claimed in claim 5, wherein the barb close on the end cranse between Point location between the highs and lows.

7. flexible support-graft as any one of claim 3 to 6, wherein each barb has a pair of skewers.

8. in flexible support-graft as described in foregoing any claim, including the flexible graft material between Hole between the first end and the second end of the pipe, the hole be used to receiving another flexible support of form of tubes- Graft.

9. kit, including flexible support-graft as described in foregoing any claim and another flexible support-shifting Plant, another described flexible support-graft are the form of graft material pipe, have and are attached to the graft material Thread reinforcing material.

10. kit as claimed in claim 9, wherein another described flexible support-graft is described with being attached to The thread reinforcing material of another graft material pipe, the thread reinforcing material are a series of along between another described pipe longitudinal direction The form of the annular cranse separated, each cranse are combined together by multiple coupling parts.