CN107405314A

CN107405314A - Cannboid comprising purifying and the composition of the combination of at least one flavonoids, terpene or mineral matter

Info

Publication number: CN107405314A
Application number: CN201680015774.9A
Authority: CN
Inventors: J·M·酷派尔; K·A·莱维
Original assignee: Emmanuel Co
Current assignee: Kenobi Growth Company
Priority date: 2015-02-27
Filing date: 2016-02-26
Publication date: 2017-11-28
Also published as: EP3261629A4; EP3261629A1

Abstract

The new compositions of the combination of the cannboid with purifying are disclosed herein.One embodiment of the disclosure provides the composition that the cannboid with one or more purifying combines with the terpene purified.One embodiment of the disclosure provides the composition that the cannboid with one or more purifying combines with the flavonoids purified.One embodiment of the disclosure provides the composition of cannboid and the mineral combinations of purifying with one or more purifying.

Description

Cannboid comprising purifying and the combination of at least one flavonoids, terpene or mineral matter Composition

Technical field

This disclosure relates to hemp industry.Specifically, this disclosure relates to cannboid, flavonoids and/or terpene comprising purifying Composition and preparation.

Background

Hemp is flowering plant category, and it has three different kinds：Ordinary hemp (Cannabis sativa), India are big Numb (Cannabis indica) and green bristlegrass grass hemp (Cannabis ruderalis).Hemp has been used to hemp fibre for a long time Dimension, medicine of being diverted oneself for seed and seed oil, for goals of medicine and conduct.

Hemp is made up of at least 483 kinds of known compounds, and the compound includes cannboid, terpenoid, flavonoids, nitrogen Compound, amino acid, protein, glycoprotein, enzyme, sugar and related compound, hydrocarbon, simple alcohols, aldehyde, ketone, simple acid, aliphatic acid, letter Monoesters, lactone, steroids, terpene, non-cannboid phenol, vitamin, pigment and element.These compounds are secreted on glandular hairs.Hemp Element is specific to cannabis plants and has had 100 kinds of cannboids to be separated into purifying (single) molecule.

Most of extraction processes are intended to extract cannboid, particularly THC (tetrahydrocannabinol) (THC).THC has many effects, including relieve pain, treat glaucoma, alleviate treatment of cancer during nausea and vomiting.The latter makees Sold for medicine Dronabinol (dronabinol).Trade (brand) name in the U.S. is Marinol.It is THC artificial pure isomer (-)-trans-Δ⁹- THC.

It is for providing sufficiently pure THC, cannabidiol (Cannabidiol) to have confirmed preparative gas chromatography (CBD) and cannabinol (Cannabinol) (CBN) sample appropriate method.In terms of the pure cannboid for being used for being studied is separated Existing difficulty.Cannboid can have collaboration or antagonism each other.Other extracting methods include butane Hash oil (butane Hash oil) (BHO) and supercritical carbon dioxide extraction.Extracted by solvent (such as butane or carbon dioxide) from plant extract Cannboid, this produces the composition of purifying.

The resin gland of more commonly referred to as base husband (kief) contains the cannboid and terpene of high concentration.The extraction process of base husband is related to Whole plant is inserted in fine screen shifter and gently vibrated so that base husband falls from plant through mesh screen.Sometimes base husband quilt It is compressed into the referred to as roundel of Hash (hash) or hashiss (hashish).

Although making progress in terms of single molecule is separated, not yet carry out preparing the specific group with purifying compound The work of the composition of conjunction.It there is no the work developed to the compound of the purifying molecule with repeatable, reliable ratio.Tool For body, progress is there is no in terms of by the cannboid of purifying and the terpene (terrene) of purifying, flavonoids and/or mineral combinations.

Needs be present to the composition of the novel compositions of the cannboid comprising purifying.Also to providing one or more purifying Special needs be present in the composition that cannboid combines with the terpene purified.In addition, to provide the cannboids of one or more purifying with Needs be present in the composition of the flavonoids combination of purifying.In addition, cannboid and the ore deposit of purifying to providing one or more purifying Needs be present in the composition of combinations of substances.

It is described in detail

The new compositions of the combination of the cannboid with purifying are disclosed herein.One embodiment of the disclosure provides tool There is the composition that one or more cannboids purified combine with the terpene purified.One embodiment of the disclosure, which provides, has one The composition that kind or the cannboid of a variety of purifying combine with the flavonoids purified.One embodiment of the disclosure, which provides, has one The composition of kind or the cannboid of a variety of purifying and the mineral combinations of purifying.

Composition is disclosed herein, it is included：

The cannboid of first purifying；With

The compound of the mineral matter of the terpene of cannboid, purifying, the flavonoids of purifying and purifying selected from the second purifying,

Wherein described composition generally not containing cellulose.

As used herein, term " purifying " means to separate from plant using chromatogram, distillation, extraction or similar technology And produce the purity more than 60%.In some embodiments, " purifying " composition disclosed herein has more than 70% Purity.In some embodiments, " purifying " composition disclosed herein has the purity more than 80%.In some embodiment party In case, " purifying " composition disclosed herein has the purity more than 90%.

Under the background of the disclosure, when compound includes Stereocenter, term " purifying " includes enantiomer-pure group Compound and the mixture for also including enantiomter or isomers.

Various solvents and technology can be used, including but not limited to ethanol, butane, methane, carbon dioxide, ice, water, steam comes Extract cannboid and other plant moleculars.Cannboid and other plant moleculars can from cultivate express desired cannboid and/or The plant extract of terpene and/or flavonoids purity overview.It can be used supercritical fluid (" SFC ") extraction and the purifying of similar technology big The plain and other molecule of fiber crops.In an example, the technique of crystallization, which is related to, inserts target compound in liquid and then cools down, or will Participate in thing to be added in solution, this declines the solubility for making target compound so that it forms crystal.In this example, connect And crystal is separated from liquid by filtering or centrifuging.

As used herein, term " cannboid " means to act on any material of Cannabined receptor.Such as term hemp Element includes cannabinoid ligand such as activator, partial agonist, inverse agonist or antagonist, such as passes through binding and function Property measure proved.In many instances, cannboid is can recognize that, " * will be big because its chemical name will include text string in title Fiber crops (cannabi) * ".Within the context of the present application, when referring to specific cannboid, each acid and/or decarboxylation form are all as single Both molecule and mixture are included.

Under the background of the disclosure, the example of cannboid includes belonging to the compound of any following molecule types, its derivative Thing, salt or the like：THC (THC), THCV (Tetrahydrocannabivarin) (THCV), hemp Chromene (Cannabichromene) (CBC), hemp chromanone (Cannabichromanon) (CBCN), cannabidiol (CBD), Hemp Ai Ersong (Cannabielsoin) (CBE), cannabidivarin (Cannabidivarin) (CBDV), hemp furans (Cannbifuran) (CBF), cannabigerol (Cannabigerol) (CBG), cannabicyclol (Cannabicyclol) (CBL), It is cannabinol (CBN), cannabidiol (Cannabinodiol) (CBND), dihydroxy cannabinol (Cannabitriol) (CBT), secondary Cannabinol (Cannabivarin) (CBV) and different cannboid.

As used herein, term " terpene " means to build or by combining isoprene on isoprenoid structural framework Organic compound caused by unit.Generally, the terpene molecule seen in plant can produce smell.

The structure of terpene is built using the isoprene as 5 carbon structures.Flavonoids is generally considered to be with two phenyl ring and miscellaneous 15 carbon structures of ring.Therefore, wherein flavonoids may be present and be considered as the overlapping of terpene.However, and not all terpene all can be considered It is flavonoids.

Under the background of the disclosure, term terpene includes hemiterpene, monoterpene alcohol, terpene ester, diterpene, monoterpene, polyterpene, tetraterpene, terpenoid Oxide, sesterterpene, sequiterpene, drop isoprene (Norisoprenoid) or derivatives thereof.

The derivative of terpene includes terpenoid, and it is in class hemiterpene, monoterpenoid, type sesquiterpene, class sesterterpene, the sequiterpene of class three (sesquarterpenoid), the form of class tetraterpene, class triterpene, class tetraterpene, class polyterpene, isoprenoid and steroids.They It can be following form：α-, β-, γ-, oxo-, its isomers or combination.

Under the background of the disclosure, the example of terpene includes：7,8- dihydroionones, navatone, acetic acid, acetyl Cedrene, anethole, anisole, benzaldehyde, bergaptene (Bergamotene) (α-cis-bergaptene) (α-trans-perfume Limonene), bisabol (β-bisabol), borneol, borneolacetate, butyric acid (Butanoic/Butyric Acid), cadinene (α-cadinene) (γ-cadinene), caffeol, caffeic acid, camphor terpene, camphor, capsaicine, carene (Δ -3- carenes), carrot Element, carvacrol, carvol, D-CARVONE, L-CARVONE, carypohyllene (β-carypohyllene), caryophyllene oxide, castor essence Oil, cedrene (eneα-cedar) (β-cedrene), cedrene epoxides (eneα-cedar epoxides), cedrol, cembrene, Chlorogenic acid, cinnamic acid (α-amyl group-cinnamic acid) (α-hexyl-cinnamic acid), cinnamic acid, cinnamyl alcohol, citronellal, citronellol, cryptone, Curcumene (α-curcumene) (γ-curcumene), capraldehyde, dehydrogenation vomiofliol, diallyl disulphide, in dihydro-actinidia Ester, dimethyl disulfide, eicosane (eicosane/icosane), elemene (beta-elemene), estragole, ethyl acetate, Chinese cassia tree Acetoacetic ester, ethylmaltol, cineole/1,8- cineoles, eudesmol (α-eudesmol) (β-eudesmol) (γ-eucalyptus Leaf oil alcohol), it is eugenol, Euphol, farnesene, farnesol, fenchol (β-fenchol), fenchone, geraniol, geranyl acetate, big Root myrcene (Germacrenes), germacrene B, guaiaci lignum -1 (10), 11- diene, guaiacol, guaiene (α-be cured Create wooden alkene), gurjunene (α-gurjunene), ayapanin, hexanal (Hexanaldehyde), caproic acid, Humuleno (α-humulus Oxalene) (β-Humuleno), ionol (3- oxygen-α-ionol) (β-ionol), irisone (α-ionone) (β- Irisone), ipsdienol, isoamyl acetate, isoamyl alcohol, isoamyl formate, isoborneol, different myrcenol, different Hu it is thin Lotus alcohol, isovaleric acid, isoprene, kahweol, lavender alcohol, limonene, gamma-Linolenic acid, linalool, longifolene, α-come into leaves Firpene, lycopene, menthol, methyl butyrate, 3- sulfydryls -2 methyl pentanal, mercaptan (Mercaptan/Thiol), β-sulfydryl Ethanol, TGA, allyl sulfhydrate, benzyl mercaptan, butanethiol, ethanethio, methyl mercaptan, furfuryl mercaptan, ethylene dithiol Alcohol, propyl group mercaptan, thenyl mercaptan, gaultherolin, methyl butenol, 2 methyl valeric acid methyl esters, methyl thiobutyrate, the moon Osmanthus alkene (beta-myrcene), γ-muurolene, nepetalactone, nerol, nerolidol, neryl acetate, aldehyde C-9, n-nonanoic acid, sweet basil Alkene, octanal, octanoic acid, p-cymene, amyl butyrate, phellandrene, phenylacetaldehyde, benzene ethyl mercaptan, phenylacetic acid, phytol, firpene, β-pinane Alkene, propanethiol, flat modeling rattan element, pulegone, Quercetin, retinol, rutin, sabinene, sabinene hydrate, cis-sabinene Hydrate, trans-sabinene hydrate, safranal, α-selinene, α-sinensal, β-sinensal, cupreol, MF59, Japanese yew two In alkene, dipentene glycol, terpineol, terpinen-4-ols, α-terpinenes, γ-terpinenes, terpinolene, benzenethiol, absinthol, hundred Phenol, alpha-tocopherol, Tonka hendecanone, the hendecanal, valeral (Valeraldehyde/Pentanal), acetic acid o-tert-butyl ring Own ester (Verdoxan), ylangene, umbelliferone or vanillic aldehyde.

As used herein, term navatone refers to the compound with anisole, and wherein aceticoceptor is in methoxy The contraposition of base, there is following structural formula：

Usual navatone is characterized by moderate strength sugariness, anise fragrance, vanilla sample fragrance, with fat Mealiness, face cream and benzaldehyde aromatic.As flavouring, it is had described as with sweet taste, anise fragrance, fruity and cherry Taste, with cosmetics vanilla aromatic.

As used herein, term acetic acid refers to the carboxylic acid with methyl.Usual acetic acid is characterized by moderate strength Sugariness, anise fragrance, vanilla sample fragrance, with cosmetics, face cream and benzaldehyde aromatic.In flavouring, it is retouched State as with sweet taste, anise fragrance, fruity and cherry-flavored, with cosmetics vanilla aromatic.

As used herein, term acetyl cedrene, which refers to, has the cedrene containing acetyl group, and has following structures The compound of formula：

Acetyl cedrene is generally characterised in that with moderate strength warm nature, wooden, amber Moschus fragrance.It can be accounted for Up to the 20% of flavor concentrate.

As used herein, term anethole refers to the aromatic compounds with following structural formula：

Anethole is generally characterised in that with extremely strong strong sugariness, anise, radix glycyrrhizae fragrance.It is used for extensive a variety of spices In flavor enhancement.It has sugariness, anise and pungent liquorice flavor, with lasting sugariness pleasant impression.Anethole also has shown that Some anti-oxidant and antimicrobial acivities.

As used herein, term anisole, which refers to, has the phenyl ring containing methoxyl group, and the change with following structural formula Compound：

Being generally characterised in that for anisole smells like anise seed.

As used herein, term benzaldehyde refers to the compound with the phenyl ring being connected with aldehyde, and it has following structural formula：

Benzaldehyde is generally characterised in that with almond benevolence sample smell.

As used herein, term bergaptene refers to including the α-suitable in purifying and/or the form of mixtures of any ratio The compound of one or both of formula-bergaptene and/or α-trans-bergaptene.α-cis-bergaptene refers to following knots Structure formula：

α-cis-bergaptene is generally characterised in that the smell with strong black pepper.It is many kinds of orchid family Aroma constituent.It also has shown that some antioxidation activities.α-trans-bergaptene refers to following structural formula：

α-trans-bergaptene is generally characterised in that with moderate strength warm nature, tealeaves sample smell.It is used for some aphids In the chemical communication system of worm kind.

As used herein, bisabol refers to the β of form of mixtures and/or the list of alpha form in purifying and/or any ratio One or both of ring sesquiterpenoid.Position based on tertiary alcohol group, beta form are different from alpha form.Alpha form refers to following structures Formula：

Beta form refers to following structural formula：

It is generally characterised in that with moderate strength citrus, flower, assail the nostrils, lemon, fresh, sugariness, draft fragrance.It is used for In the chemical communication system of anthonomus grandis (Cotton boll weevil).It has shown that anti-inflammatory, it is antimicrobial, antimycotic and Antimutagenic activity.

As used herein, term borneol refers to the compound with following structural formula：

It is generally characterised in that with the very smell of the camphoraceous menthol flavor of class and easily changes into menthol. In Chinese medicine, the herbal medicine containing borneol is recommended for tired and overstretched.In Chinese medicine, borneol is considered as " sedative ". It recovers for fatigue from disease and pressure.It to see in many essential oil on a small quantity.Commercially, it plants from absinth Thing, such as Wormwood and some Chinese cassia tree kinds.

As used herein, term borneolacetate refers to borneol group, has the acetic acid esters of following structural formula：

It is generally characterised in that with pine tree, camphor, herbal medicine and balsamic odour.

As used herein, butyric acid refers to the carboxylic acid with following structural formula：CH₃CH₂CH₂COOH.It is generally characterised in that tool Have and be commonly found in unacceptable sharp aroma in the case of perspiration, flatulence and corrupt butter.Because it is much hydrochloric acid in gastric juice In contribute to decompose food to obtain one kind of energy, so it is the main original of the rancid smell related to people's vomitus Cause, and it is common additive in stinkbomb for this reason.

As used herein, term cadinene refers to α-cadinene in the form of mixtures of purified form or any ratio And/or one or both of γ-cadinene.α-cadinene refers to the isomerization hydrocarbon sesquiterpene with following structural formula：

α-cadinene be generally characterised in that with excitant, the people that chokes, wooden, guaiaci lignum sample smell.It is classified as by FDA Allow to be added directly to the food additives in the food of human consumption.It has shown that some antimicrobial, anticancers, anti-inflammatory, Anti-oxidant and anti-malarial activity.γ-cadinene refers to the compound with following structural formula：

γ-cadinene is generally characterised in that with draft, herbal medicine, wooden fragrance.It has shown that some are antimicrobial And antibacterial characteristic.Many kinds of termite and a small number of beetles utilize γ-cadinene in their chemical communication system.

As used herein, term caffeol refers to the diterpene molecule with following structural formula：

It, which is generally characterised in that, is largely present in unfiltered coffee.Also have shown that it has anticancer special in rats Property.

As used herein, term caffeic acid refers to both phenol functional group and acrylic-functional, has following structures The compound of formula：

As used herein, term camphor terpene refers to the bicyclic diterpene with following structural formula：

Camphor terpene is generally characterised in that with excitant, herbal medicine, fir-needle smell.Its smell is described generally as camphor tree It is brain taste, nice and cool, pine and wooden, with terpyridyl aromatic (terpy nuance).It has citrus and jerky Mint flavored and jerky acrid odors.Camphor terpene is used in spices and food additives.It is much essential oil, such as rosin, Cypress essential oil, camphorated oil, citronella oil, neroli oil, ginger oil and the submember of valerian.

As used herein, it is similar with camphor terpene but instead have the terpenoid of ketone rather than double bond to refer to structure for term camphor, With following structural formula：

Camphor has the smell of great characteristic, thus tree is named.Most of containing Camphora extract can approve product It is drug containing chest wiping agent, it has identical distinctive odor.This is strong penetration, long-lasting odor.It is as chewing gum and firmly Flavor enhancement and aromatic in sugar.The therapeutic characteristic of camphorated oil is analgesia, antidepression, anti-inflammatory, antibacterial, cardiac stimulant, wind dispelling, profit Urinate, bring down a fever, hypotensive, kill insect, defaecation, send out red, stimulation, sweating, expelling parasite and treat wound.

As used herein, term capsaicine refers to the compound with following structural formula：

In the case of its pure form, capsaicine be typically do not have it is odorous.It is generally characterized as the thorn of mammal Swash thing, it is well-known because of the sensation that it is evoked when being inhaled into, eating or be applied to skin.In this sense, itself and peppermint Alcohol is similar (menthol stimulates the receptor of body without causing actual temperature change).Capsaicine generally in local ointment and It is used as in skin paste to lenitive antalgesic and as antiphlogistic.

As used herein, term carene (Δ -3- carenes) refers to the bicyclic diterpene with following structural formula：

It has double bond from camphor and the different of camphor terpene in ring structure.Δ -3- carenes are generally characterised in that tool There are moderate strength sugariness, excitant citrus smell.It is the composition of pine tree and cedar resin but sees many other plants, is wrapped Include in rosemary.In champignon therapy, the cupressin rich in Δ -3- carenes is used for dried more body fluid, tears, nasal mucus, mistake More menstruations and sweat.Think that its at least part causes dry and eye to do problem, described problem is some hemp users experience Common adverse effect.

As used herein, term carrotene refers to formula C₄₀H_xA series of related unsaturated hydrocarbons materials in any Person.- carrotene has following structural formula：

Under the background of the disclosure, term carrotene refers in any different of the form of mixtures of purifying and/or any ratio The carrotene of structure form.Carrotene is generally characterised in that human eye appears to be colour.

As used herein, term carvacrol refers to the monoterpenoid phenol with following structural formula：

Carvacrol is generally characterised in that the excitant with wild marjoram (oregano), warm nature smell.It is used as flavor enhancement and Aromatic and its flavor have described as acidity, herbal, phenol, the property of medicine and woody cotton.Carvacrol typically results in The bioactivity of wild marjoram.Carvacrol shows many different activities, such as：Antimicrobial, antitumor, anti-mutagenesis, anti-genetoxic, Analgesia, anti-spasm, anti-inflammatory, angiogenic, anti parasitic, antiplatelet, AChe suppression, elastase inhibitor, kill insect, anti-liver poison Property and liver-protecting activity.

As used herein, term carvol refers to the structure still class list with carbonyl rather than alcohol radical similar with carvacrol Terpene.For the situation of the disclosure, term " carvol " includes the enantiomerism of the form of mixtures in purifying and/or any ratio Body form S- (+) and R- (-).

As used herein, term D-CARVONE refers to S- (+) enantiomter with following structural formula of carvol：

D-CARVONE is generally characterised in that with pungent, toast bread, caraway fragrance.It sees orange peel oil and gingergrass oil In.It is the oily main component (60-70%) from Semen Coriandri.

As used herein, term L-CARVONE refers to R- (-) enantiomter of carvol, and it has following structures Formula：

L-CARVONE is generally characterised in that with sugariness, peppermint, draft, spearmint smell.Its see spearmint and In kuromoji oil.It is widely used in chewing gum and flavored oils such as spearmint, but be also used for air freshener, perfume, Shampoo, deodorant, shower cream, laundry detergent, cosmetics and toothpaste spices and fragrance of a flower spices in.

As used herein, term carypohyllene (β-carypohyllene) refers to the bicyclic sequiterpene with following structural formula：

β-carypohyllene is generally characterised in that with sugariness, wooden and dryness cloves smell and has pepper, pungent gas Taste, with camphor and astringent taste citrus background smell.It is the main terpene seen in black pepper, cloves and cotton.Its generally with compared with Small percentage is seen in many other leafy green vegetables, herbal medicine and spices.Carypohyllene contributes to the acidity of black pepper.Carypohyllene oil Also industrially it is used to strengthen tobacco flavor.

As used herein, term caryophyllene oxide refers to the compound with following structural formula：

Caryophyllene oxide is generally characterised in that with lemon Balm smell.It has shown that as insecticide/ Certain effect of antifeedant and broad-spectrum antifungals as plant defense.The characteristic of caryophyllene oxide, which is that, to be caused by seizing Malicious dog carries out the key component of hemp discriminating.

As used herein, term cedrene refers to the eneα-cedar of the form of mixtures in purified form or any ratio And/or one or both of β-cedrene.The difference of (-) α and (+) beta form is the position of double bond.Eneα-cedar, which refers to, to be had The compound of following structural formula：

Alpha form is generally characterised in that with moderate strength is wooden, sugariness, fresh deodar fragrance.It is used for baked items, Sherbet and sherbet.It is the main component of cedar essence oil.

Beta form refers to the compound with following structural formula：

Beta form is generally characterised in that with moderate strength is wooden, fresh deodar fragrance.It is the main of cedar essence oil Composition.

As used herein, term cedrene epoxides (eneα-cedar epoxides) refers to epoxide group and had There is the cedrene of following structural formula：

Eneα-cedar epoxides be generally characterised in that with moderate strength is wooden, amber, tobacco, santal and fresh day Zhu is mint flavored.It is typically used as the aromatic of cosmetics and hair pastil.

As used herein, term cedrol refers to the sesquiterpenoid with following structural formula：

Being generally characterised in that for cedrol has extremely faint sugariness, soft, dryness and the wooden fragrance of deodar.Research is Show cedrol display depth sedation when being inhaled into.Cedrol is the key component of cedarwood oil.It sees pine and cypress In essential oil, especially in cypress and needle juniper.It is also in the green plant marjoram (Origanum related to wild marjoram Onites identified in).

As used herein, term cembrene A refers to the monocyclic diterpene with following structural formula：

It is generally characterised in that with faint waxy smell.

As used herein, term chlorogenic acid refers to the ester with following structural formula of caffeic acid and a (-)-chinic acid：

It can be commonly found in peach, prune and jerky coffee bean extract.

As used herein, term cinnamic acid refers to the phenyl being connected with unsaturated aldehyde, has following structural formula：

Cinnamic acid is generally characterised in that with extremely strong pungent, sugariness cinnamic odor, and assigns Chinese cassia tree its flavor. It is naturally occurring in other kinds of bark of xylocinnamomum and camphor tree category.Cinnamic acid accounts for the 90% of Chinese cassia tree essential oil.

As used herein, term α-hexyl-cinnamic acid refers to the compound with following structural formula：

α-hexyl-cinnamic acid is generally characterised in that with moderate strength sugariness, the fragrance of a flower, jerky, jasmine, citrus and fruity Fragrance, with cosmetics, ardent or acrid odors.As flavouring, it is sugariness, wax, the fragrance of a flower and jerky, with citrus With fruity aromatic.

As used herein, term α-amyl group-cinnamic acid refers to the compound with following structural formula：

α-amyl group-cinnamic acid is generally characterised in that with the medium sugariness fragrance of a flower, oiliness, fruity, herbal medicine, jasmine and ardent Fragrance.Used in flavouring, it is ardent, wax, the fragrance of a flower, rose taste and honey sample, with fruity aromatic and main body.

As used herein, term cinnamic acid refers to propionic acid with doubly linked phenyl, has following structural formula：

Cinnamic acid is generally characterised in that with faint face cream, sugariness, styrax, honey sample smell.It can be from Chinese cassia tree Oil, or obtained from face cream such as styrax.

As used herein, term cinnamyl alcohol refers to propyl alcohol base with doubly linked phenyl, has following structural formula：

Being generally characterised in that with moderate strength cinnamon flavor of cinnamyl alcohol, the fragrance of a flower is jerky and fermentative smell, with cosmetics Property face cream aromatic.As flavoring ingredient, it has the jerky, fragrance of a flower, pungent and honey flavor, with fermented yeast aromatic.

As used herein, term citronellal refers to the monoterpenoid with following structural formula：

Being generally characterised in that of citronellal accounts for the leaf oil from kaffir lime leaf up to 80% and is to cause its special Levy the compound of fragrance.Citronellal has the high repellent validity of resistance mosquito and other insects.Also it is strong to have shown that it has Big antimycotic property.Citronellal is to confer to the key component of its unique lemon-lime smell of citronella oil.

As used herein, term citronellol refer to including (+) in purified form or the form of mixtures of any ratio and The acyclic monoterpenoid of one or both of (-) enantiomter.(+) enantiomter has following structural formula：

(-) form has following structural formula：

Citronellol is generally characterised in that with the fragrance of a flower, rose taste, sugariness, citrus taste, fragrant with jerky, fatty, terpene Regulating the qi flowing in the channels taste.Used in flavouring, it has the fragrance of a flower, rose taste, sugariness, jerky taste, with fruity citrus aromatic flavor.Grinding In studying carefully, show that it has deep sedation effect after being inhaled into.

As used herein, term cryptone refers to 4- isopropyl -2- cyclohexene -1- ketone and has following structural formula：

It is generally characterised in that with wooden peppermint draft smell.

As used herein, term curcumene refers to C₁₅H₂₂, including in purified form or the mixture shape of any ratio α-curcumene of formula and/or the compound of one or both of γ-curcumene.α-curcumene has following structural formula：

α-curcumene is generally characterised in that the smell with turmeric.It is mainly seen in the zingiber of ginger.It is turmeric with A kind of main active of both ginger oils.γ-curcumene has following structural formula：

γ-curcumene is generally characterised in that with soil fragrance.It is mainly seen in Zelanian Bidwell Xiao Nan In (Libocedrus bidwillii) tree.It is a kind of main active of both turmeric and ginger oil.

As used herein, term capraldehyde refers to the ten carbon aldehyde with following structural formula：

Capraldehyde is generally characterised in that with extremely strength wax, orange peel, citrus sample, sugariness, aldehyde smell.It is used for perfume (or spice) In material and flavouring.Its flavor is wax, fatty, citrus and orange peel taste, with slightly jerky muskmelon aromatic.Capraldehyde is present It is the important component in citrus in nature and together with octanal, citral and sinensal.

As used herein, term dehydrogenation vomiofliol refers to the ring terpenoid oxide with following structural formula：

Dehydrogenation vomiofliol is generally characterised in that with fruity and floral odor.It has shown that certain cell suppression System and antiviral activity.

As used herein, term diallyl disulphide refers on each sulfide with pi-allyl and with following The disulphide of structural formula：

Diallyl disulphide is generally characterised in that with strong green onion, onion and garlic sample smell, with metal aromatic. When high dilution, it is used as the flavouring in food.It has jerky onion and garlic sample flavor, with abundant aromatic.Its It is derived from the organic sulfur (organic compound containing sulphur) of garlic.It is also a kind of key component of the distilled oil of garlic.Diene Dipropyl disulfide has many health benefits of garlic, but it is also the anaphylactogen for causing garlic allergy.

As used herein, term dihydroactinidiolide refers to the terpenoid oxide with following structural formula：

Dihydroactinidiolide is generally characterised in that with fruity, Moschus, cumarin tea sample, peach fragrance.It is to use In food and the flavor enhancement of tobacco and for tea flavouring, berry, other flavoring agent of fruit, brown flavoursome agent, sea In grass, tomato and beer.It has shown that anti-proliferative effect.

As used herein, term dimethyl disulfide refers to the disulphide that each sulfide is connected with methyl, has Following structural formula：

Dimethyl disulfide is generally characterised in that with high intensity sulphur, rot garlic, cabbage or onion type Fragrance.Dimethyl disulfide is together with the chemical combination that diformazan substratess and dimethyltrisulfide are by being referred to as the plant discharge of dead horse Alocasia ordora Thing.The smell of fly stench meat caused by the combination of three attracts, and they help to pollinate for this plant.

As used herein, term eicosane refers to formula C₂₀H₄₂, there are 366,619 constitutional isomers, have following The alkane of skeleton structure：

Eicosane is generally characterised in that with wax smell.It is used in flavor concentrate.It is to be used to form candle Paraffin seen in most short compound.It is also used in pest repellant.

As used herein, term elemene (beta-elemene) refers to the ring-type sequiterpene with following structural formula：

Beta-elemene is generally characterised in that with moderate strength sugariness fragrance.The beta-elemene of parenteral form is isolated from Curcuma zedoary (Rhizoma zedoariae), i.e., a kind of ginger, but it is in plant product (botanical) such as celery, peppermint Seen volatility terpene, and it is universal in various medicinal plants.Its for broad-spectrum tumor have powerful anti-proliferate and Antitumaous effect.

As used herein, term estragole refers to the propenyl benzene with following structural formula：

It is the isomers of anethole, is a difference in that the position of double bond.It is generally characterised in that with anise seed Smell is simultaneously present in tarragon oil, rosin and other essential oil, and in perfume and flavoring.

As used herein, term ethyl acetate refers to the ester of ethanol and acetic acid.Being generally characterised in that for ethyl acetate has Moderate strength acidity fruity, dirt, cheese, fermentative smell, with Luo Kefu cheese (Roquefort cheese) strong perfume (or spice) Adjust.It is used as with fruity, dirt, the flavouring of acid flavor, with dairy products, butter and cheese aromatic.

As used herein, term ethyl cinnamate refers to the ester of cinnamic acid and ethanol, and it has following structural formula：

Ethyl cinnamate be generally characterised in that with moderate strength sugariness, face cream, pungent, cosmetics, fruity, berry and Plum smell.It is used as flavor enhancement, wherein its have face cream, cosmetics, fruity, berry, punch (punch), spices, sugariness and Jerky flavor, with amber odor.

As used herein, term ethylmaltol refers to formula C₆H₆O₃Cyclic organic compounds, it has following knots Structure formula：

It, which is generally characterised in that, has and sweet taste as caramel and boiling fruits.

As used herein, term cineole/1,8- cineole refers to cyclic ether and monoterpenoid, and it has following structures Formula：

The camphor mint flavored being generally characterised in that with eucalyptus of cineole/1,8- cineoles.In fact, it is eucalyptus Main component in oil.It is also seen in other fragrant plants.When locally applying, it is used to increase circulation and mitigates pain And swelling.Cineole readily penetrates through blood/brain barrier, may also contribute to other cannboids and be easier to pass through.The suction of cineole Generally increase brain blood flow and strengthen cortical activity.When being combined with hemp that is oral or sucking, the effect of cineole is reported To be extremely exciting, hence it is evident that increase mind ＆ body energy.This terpene can cause with similar big with other terpenes such as it Report difference between the effects between the cunjah of the plain overview of fiber crops and ordinary hemp strain.

As used herein, term eudesmol refers to α-eucalyptus oil in the form of mixtures of purified form or any ratio Alcohol, β-eudesmol or γ-eudesmol.α-eudesmol has following structural formula：

α-eudesmol is generally characterised in that with sugariness, woody odor.Have shown that it is protected in rats To exempt from the brain damage after focal ischemia.α-eudesmol is applicable to treat migraines.β-eudesmol refers to following structures Formula：

β-eudesmol is generally characterised in that with sugariness, jerky, wooden, shaddock sample fragrance.It has shown that necessarily Anti-oxidant, antimicrobial and anti-wood-rotting fungi activity.γ-eudesmol refers to following structural formula：

γ-eudesmol is generally characterised in that with wax, sugariness, wooden, floral odor.γ-eudesmol is to cancer Cytotoxic effect is presented in cell.All eudesmol isomers all show cytotoxicity to different tumor cell lines.

As used herein, term eugenol refers to the propenyl benzene with following structural formula：

Being generally characterised in that for eugenol produces the typical aromatic odor of cloves.It is sometimes referred to as caryophyllus oil, because It is the active component in cloves.Eugenol is seen in insect attractant and UV absorbents.It is antioxidant, and is worked as When being mixed with zinc oxide, eugenol is the Typical matrices for filling temporarily.This is the reason for dental clinic's smell is identical.

As used herein, term Euphol refers to the tetracyclic triterpene with following structural formula：

As used herein, term farnesene refers to six kinds of closely related compounds as sequiterpene.(E, E)-α-method Alkene is one kind in this six kinds of molecules and has following structural formula：

Under the background of the disclosure, term " farnesene " refer to independent in six kinds of closely related compounds or with that six kinds it is close Any other compound in cut related compounds combines any.One aphid kind discharges farnesene as defense mechanism. It is generally characterised in that the fragrance with Magnoliaceae flowers and with citrus smell, with jerky, wooden, plant scent and Micro mela.

As used herein, term farnesol refers to the ring-type sesquiterpenoid with following structural formula：

Farnesol is generally characterised in that with faint, gentle, fresh, sugariness, the fragrance of a flower, lime tree smell.It is used as making up Reagent in product, flavor enhancement and spices.It is with anti-inflammatory, anti-oxidant and anti-proliferative effect and has shown that it is served as with certain The chemoproection for potentiality of easing pain and antitumor agent.Farnesol is present in many essential oil, such as lemongrass, neroli oil, cyclamen, lemon In lemon lemongrass, tuberose, rose, Moschus, face cream and balsam of tolu.It is used in perfume, to protrude the gas of sugariness fragrance of a flower perfume Taste.It is also the natural insecticide of acarid and is the pheromones of several other insects.

As used herein, term fenchol (β-fenchol) refers to the isomers of borneol, and it has following structural formula：

β-fenchol is generally characterised in that with camphor, borneol, pine, wooden, dryness, sugariness, lemon smell.It is used as Flavor enhancement and aromatic.It is the antioxidant and antimicrobial with limited antifungal property.

As used herein, term fenchone refers to monoterpene and ketone with following structural formula：

Fenchone is generally characterised in that with camphor, arbor-vitae, cedar leaf, herbal medicine, soil, wooden fragrance.As addition Agent, its flavor has described as nice and cool, camphor taste, sugariness and mint flavored, with old soil aromatic.

As used herein, term geraniol refers to the monoterpenoid with following structural formula：

Geraniol is generally characterised in that with the moderate strength fragrance of a flower, sugariness, rose taste, fruity smell, with citrus extremely Lemongrass sample smell aromatic.Its flavor is the fragrance of a flower, rose taste, wax and perfume sample, with fruity peach sample aromatic.It is used as seasoning Agent and aromatic.It is used for flavor enhancement such as peach, raspberry, grape fruit, red apple, plum, bitter orange, orange, lemon, watermelon, spinach In trailing plants and blueberry.It also serves as aromatic and is used for cosmetics.Geraniol is natural.It suppresses DNA synthesis.At one In research, display geraniol suppresses pancreatic tumor growth.

As used herein, term geranyl acetate refers to the monoterpene with carboxylic acid, has following structural formula：

Being generally characterised in that with extremely intense floral odor taste for geranyl acetate, winds with fruity.It is seen from plant In the thing such as various natural oils of lemongrass, lemon grass, yellow camphor tree, rose and many other plants.Its displaying is powerful antimicrobial Characteristic.

As used herein, term geranyl farnesol refers to the acyclic 25- carbons isoprene with following structural formula：

As used herein, term germacrene indicates a kind of volatile organic hydrocarbon of really sequiterpene.For this public affairs The purpose opened, term " germacrene " refer to five kinds of isomers in any combinations form of purified form or five kinds of isomers Any isomers.Germacrene A refers to following structural formula：

Germacrene B refers to following structural formula：

Germacrene C refers to following structural formula：

Germacrene D refers to following structural formula：

Germacrene E refers to following structural formula：

They are produced generally in many plant species to play their antimicrobial and insecticidal properties, but they It may also function as the effect of insect pheromone.The spy of the essential oil of red wild nettle (white dead nettle (Lamium purpureum)) Sign is that it has the germacrene of high content.Germacrene B be generally characterised in that with scope from pungent, warm nature and Earthy Taste extremely squeezes the tangy of the sugariness fragrance of lime oil.It is not used in food or spices.

As used herein, term guaiaci lignum -1 (10), 11- diene refer to the bicyclic sequiterpene with following structural formula：

Guaiaci lignum -1 (10), 11- diene are generally characterised in that with the pleasant and wooden fragrance of sugariness.It is used as spices In from food additives, for enhancing flavor broad range product of regulator for smoking flavor of tobacco and general cosmetics most room.

As used herein, term guaiacol refers to the organic compound with the phenylol for containing methoxyl group at ortho position, With following structural formula：

Guaiacol is generally characterised in that with strength cigarette sample, phenol, pungent, wooden, a little drug smell.It has Sugariness, cosmetics, old, vanilla, the fragrance of a flower, almond benevolence flavor.It is mainly used as expectorant, but also serve as local anesthetic, Antiseptic and enteron aisle disinfectant.Guaiacol is various flavorants, such as the precursor of eugenol and vanillic aldehyde.

As used herein, term guaiene (α-guaiene) refers to the bicyclic sequiterpene with following structural formula：

α-guaiene is generally characterised in that with moderate strength sugariness, soil, wooden, face cream, pepper fragrance.It is used Make baked items, cereal and bread basket, including flour and starch from root and stem tuber, beans and legume, and food With the flavor enhancement and aromatic in ice, including sherbet and sherbet.α-guaiene assign soil, pungent fragrance and Taste.α-guaiene displays that inflammatory properties.

As used herein, term gurjunene (α-gurjunene) refers to the tricyclic sesquiterpene with following structural formula：

α-gurjunene be generally characterised in that with slightly, wooden, balsamic odour.It can be used in cosmetics and spices.. It is antimicrobial and antibacterial agent to have shown that it.

As used herein, term ayapanin refers to the derivative of the methoxyl group with following structural formula of cumarin Thing：

Ayapanin is commonly found in herniary (Herniaria glabra), three arteries and veins eupatorium (Ayanpana Triplinervis in), and kind (mahaleb cherry (P.mahaleb), Binzhou cherry of Lee (Prunus) category (P.pensylvanica) and geneva poplar (P.maximowiczil)) in.

As used herein, term hexanal refers to the aldehyde with following structural formula：

Hexanal is generally characterised in that with extremely strength, permeability, jerky, the fresh cutting grass smell of fat.Its For in flavor enhancement industry, to produce jerky wooden, plant, apple, green grass, citrus and orange taste, with fresh persistently pleasant impression Fruity flavor.

As used herein, term caproic acid refers to the carboxylic acid derivates of hexane, and it has following structural formula：

Caproic acid is generally characterised in that with excitant, oiliness, pungent, acid, fatty, stink with perspiration, rancid cheese smell. It is used as flavor enhancement and in cosmetics.It is naturally to see the aliphatic acid in various animal tallows and oil.It is to confer to A kind of chemical substance of its peculiar undesirable smell of the rotten sarcotesta of ginkgo.

As used herein, term Humuleno refers to α-Humuleno in purified form or any type of form of mixtures And/or one or both of β-humulus grass alkene isomer.They are the monocyclic sesquiterpenes with 11 yuan of rings.α-Humuleno refers to following Structural formula：

α-Humuleno (old names：α-carypohyllene) be generally characterised in that with have described as it is bitter, medium wooden and The fragrance of hop aroma.α-Humuleno has shown that inflammatory properties.Humuleno is in hop plant hop (Humulus Lupulus caused a kind of essential oil in flower cone).The concentration of Humuleno is different in different plant varieties, but can be more Up to the 40% of the essential oil of noble hops (noble hops).

As used herein, term ionol refers to the antioxidant in one group of strain space sterically hindered phenol, and it has following Structural formula：

It is also referred to as Yoshinox BHT (BHT).For the purpose of this disclosure, " ionol " also refer in purifying and/ Or the 3- oxos-α-ionol and/or β-ionol of the form of mixtures of any ratio.The feature of β-ionol is usual It is with sugariness, wooden, herbal medicine, fruity, the fragrance of a flower, violet, ardent and berry fragrance.As flavouring, it is the fragrance of a flower, purple Rowland sample, fruity, wooden, berry flavors, with cosmetics aromatic.

As used herein, term irisone refers to one group of compound referred to as rose ketone, in purified form or appoints One or both of α-ionone and/or alpha, beta-lonone of the form of mixtures of what ratio.α-ionone refers to following Structural formula：

Alpha, beta-lonone refers to following structural formula：

Alpha, beta-lonone is generally characterised in that with the fragrance of a flower, violet, raspberry smell.It is the important tribute of rose scent Thing is offered, although its concentration is relatively low, and is the important aroma chemicals used in perfume.From grape carotenoid Alpha, beta-lonone played an important role in terms of the flavor of some red wine.The flavor that alpha, beta-lonone assigns grape wine is ripple Fruity/floral character floral the component of some most popular red wine of the more, Burgundy of that and Rhone paddy.Alpha, beta-lonone shows Show powerful anticancer activity and antifungal property.

As used herein, term 7,8- dihydros-α-ionone refer to following structural formula：

As used herein, term ipsdienol refers to the terpene alcohol with following structural formula：

It is generally characterised in that with face cream, pine scent.It is the main component of the fragrance of a flower spices of several orchid kinds.Tooth Bark beetle dienol is also a kind of main aggregation pheromone of bark beetle, and wherein it is believed to be mating attractant.

As used herein, term isoamyl acetate refers to the ester formed by isoamyl alcohol and acetic acid, and it has following structural formula：

It, which is generally characterised in that, has the overpowering odor similar with banana and pears.

As used herein, term isoamyl alcohol refers to the 3- methyl-1-butanols with following structural formula：

It is generally characterised in that with excitant, fermented type, fusel oil, alcohol sample, ethereal cognac (cognac) fragrance, companion There are fruity, banana and molasses smell.It is used as flavor enhancement and aromatic.Its flavor and fusel oil, fermented flavour, fruity, banana, ether Taste is similar with cognac.

As used herein, term isoamyl formate refers to the formic acid 3- methylbutyl butenoates with following structural formula：

It is generally characterised in that with moderate strength ethereal, grape wine, dryness, soil, fruity, jerky, plum, blackcurrant Fragrance.As flavouring, it has strong, jerky, apple and fruity flavor, with wine, fat note.

As used herein, term isoborneol refers to the isomers in diverse location with alcohol radical of borneol, has following knots Structure formula：

Isoborneol is generally characterised in that with camphor, sugariness and old, India's ink sample fragrance.It has shown that antioxygen Change, anti-inflammatory and some limited antimicrobial properties.It is used as the flavor enhancement of drink, ice cream, candy, bakery and chewing gum And aromatic.

As used herein, the different myrcenol of term refers to the monoterpenoid with following structural formula：

It is generally characterised in that with the fresh, fragrance of a flower, bitter orange sample smell.Different myrcenol be used for spruce bark beetle, In the chemical communication system of slash pine beetle and double backbone bark beetles.

As used herein, term isopulegol refers to the C with following structural formula₁₀H₁₈0：

It is generally characterised in that with band sweet gas taste in moderate strength peppermint, nice and cool and hardship.It is in candy and chewing gum As flavor enhancement and aromatic.It is seen in hesperozygis rhododon shrubs, and in eucalyptus citriodora.It is also commonly used for In cosmetics.

As used herein, term isovaleric acid refers to the 3 Methylbutanoic acid with following structural formula：

It is generally characterised in that with intense irritation, acidity, smelly pin and stink with perspiration cheese taste.It is to cause undesirable foot odour Main component.However, its volatility ester has pleasant smell and is widely used in perfume.As flavouring, it is Cheese, dairy products, sweet cream butter, fermentation, wax and berry taste.It is had shown that as the effective of anticonvulsant and antidepressant Property.

As used herein, term isoprene refers to 2- methyl isophthalic acids, 3- butadiene.Isoprene, which is considered to be, is connected to one Rise to provide the monomer of structural framework for most of terpenes.

As used herein, term kahweol refers to related to caffeol in structure, has the diterpene of following structural formula：

As used herein, term lavender alcohol refers to the form of mixtures in purified form or any ratio, in its R and S The monoterpene alcohol of enantiomter, there is following structural formula：

(R) enantiomter is generally characterised in that with the faint fragrance of a flower, herbal odor, with slightly lemon sample, citrus Fruity aromatic.(S) enantiomter is generally characterised in that with faint odor.

As used herein, term limonene refers to the liquid hydrocarbon as cyclic monoterpenes, has following structural formula：

Limonene is generally largely seen in cannabis resin and tropical fruit (tree) skin and many other fruit and flowers.Definite gas Taste by terpene structures shape.Plant drives away predator using limonene.Such as fly has one group functionally with ours The similar receptor of taste bud on tongue.Harmful chemical is detected in one of they, and limonene is made a response, such as It is poisonous with it.This is hardwired in the brain of fly.Limonene is strength antibacterium, antimycotic and anticancer.Limonene It has been used clinically for dissolving gall stone, improve mood and alleviating heartburn and gastrointestinal reflux.Have shown that limonene is being tested Breast cancer cell is destroyed in the experiment of room, and its strength anti-microbial effect can kill pathogenic bacteria.Limonene spraying is also used for controlling Treat depression.Limonene be second, third in nearly all cannabis resin or the 4th most common terpene and its be synthesis it is other The precursor of cannboid.Limonene is highly absorbed in the target analyte and is quickly present in blood flow by suction.Since it is known limonene can shadow Membrane passage is rung, so it allows more THC to reach brain cell and increases the absorption of other terpenes.The design of limonene Contribute to by rapid osmotic blood-brain barrier and direct response.Result is systolic pressure increase.Subjective alertness is reported in one test And uneasiness.

As used herein, term gamma-Linolenic acid refers to the aliphatic acid with following structural formula：

It is generally characterised in that with vegetable oil fragrance slightly, light.Because it is mainly seen in vegetable oil Unrighted acid.It sells as meals and healthy replenishers, but the evidence of any validity is all very limited, and As just slightly anti-inflammatory and blood thinners.

As used herein, term linalool refers to the terpene alcohol with following structural formula：

Linalool is now tested for treating the cancer of a few types.It is also several calm essential oil (including lavender Oil) component, it is it is believed that have antianxiety and calm characteristic.In the test of the people to sucking it, it causes severe is calm to make With.In the test to laboratory rat, it makes their activity reduce almost 75%.Except being pressed as antianxiety and regulation Outside the compound of power, linalool is also strong anticonvulsant, and it also makes thrombocytin-acceptor transmission amplification, anti-so as to assign Depression effect.During local application, linalool can cure acne and skin burn without scar.Due to their sedation, Strain rich in linalool may be particularly advantageous for the patient that is had a sleepless night.

As used herein, term bergamio refers to the acetic acid esters of linalool, and it has following structural formula：

Linalool is generally characterised in that with the liliaceous fragrance of a flower aftertaste in spring flowers such as mountain valley, but is had pungent Overtone.It is terpenoid main in lavender.It is refined from lavender, neroli oil and other essential oil.People perceive its The as little as smell of hundred a ten thousandth ratios in air.

As used herein, term longifolene, which refers to, has (+) and (-) enantiomter, the liquid as tricyclic sesquiterpene Hydrocarbon.(+) enantiomter refers to following structural formula：

For the purpose of this disclosure, term " linalool " refers to it in the form of mixtures of purified form or any ratio Any one of (+) and/or (-) enantiomter.It is generally characterised in that with moderate strength sugariness, wooden, rose taste, medicine Thing, fir-needle smell.Longifolene is also one of two kinds of most abundant flavor components of Lapsang souchong black tea, because the tea is in pine The upper sootiness of tree fire.Norway spruce produces longifolene as its primary product.

As used herein, term α-longipinene refers to the bicyclic sequiterpene with following structural formula：

It is generally characterised in that with pine aroma smell.Norway spruce produces the high-caliber α-come into leaves inferior to longifolene Firpene is as its primary product.

As used herein, term lycopene refers to the symmetrical tetraterpene formed by 8 isoprene units, has following Structural formula：

It is also regarded as carrotene.It is to produce red pigment.

As used herein, term cyanidenon refers to the flavonoids with following structural formula：

It is commonly found in leaf, shell, bark, honeysuckle and ragweed pollen.

As used herein, term menthol refers to the hexamethylene with following structural formula：

Menthol is generally characterised in that with extremely strong nice and cool, menthol, peppermint, peppermint fragrance and flavor. It is obtained from peppermint oil, peppermint or other peppermint oils.Menthol has local anaesthesia and anti-irritant property, and its is extensive Slightly had sore throat for alleviating.Menthol also functions as faint κ opioid receptors activator.Menthol be inhaled into, eat or Cause the known nice and cool sensation that it is evoked when applying to skin.In this sense, it is similar with capsaicine, the capsaicine It is the pungent chemical substance for causing pimiento (it stimulates thermo receptor, does not also cause actual temperature change).

As used herein, term methyl butyrate refers to the methyl ester of the butyric acid with following structural formula：

It is generally characterised in that with sulfur-containing aroma, with being adjusted before egg and cheese smell, and tomato, tropical fruit (tree). During in flavor enhancement, its taste is adjusted before old, sulphur, Limburg type (Limburger-type) cheese, with metal cheese Main body.Smell is described as sulphur, cheese sample, rotten, cabbage or garlic flavour.

As used herein, term 3- sulfydryls -2 methyl pentanal refers to the aldehyde with mercaptan and methyl, has following structures Formula：

It is generally characterised in that with extremely thick and heavy sulphur, savoury, green onion, garlic smell, with tropical fruit (tree) and fermentation Dairy products aromatic.As flavouring, it has sulphur, green onion, savoury flavor, with boiling onion and fries garlic smell and mango With the tropical fruit (tree) aromatic of passion fruit.

As used herein, term 3- sulfydryls -2- methyl anyl alcohols refer to the amylalcohol with mercaptan and methyl, have following structures Formula：

It is generally characterised in that with extremely strong sulphur, onion type fragrance.It is used for flavouring as food additives In, but it is not used as spices.Due to its intensity, it is recommended to be smelt in the case of 0.10% or lower concentration solution by news.

As used herein, term mercaptan refers to the organosulfur compound of the sulfydryl containing bond with carbon.It is typically characterized To be added to contribute to detect the key odor composition of natural gas (its purified form be do not have odorous), and " natural gas Smell " be due to the mercaptan as odorant smell.

As used herein, term beta -mercaptoethanol refers to the ethanol with mercaptan (thiol/mercaptan) group, has Following structural formula：

It, which is generally characterised in that, with extremely strong and permanent fragrant, the fragrance there are all basic addled egg sulphur to smell as of rotten fish Smell.This is the smell extremely similar to enteron aisle and skunk.

As used herein, term TGA refers to the carboxylic acid with thiol group, has following structural formula：

It is generally characterised in that with undesirable, strong, pungent, skunk smell, with enough persistence.

As used herein, term allyl sulfhydrate refers to pi-allyl and mercaptan compound with following structural formula：

It is generally characterised in that with high intensity sulphur and green onion, sauteeing onions and garlic perfume, with toasting, scorch and burn Abundant aromatic.It is used as flavor additives useful and is described as green onion taste onion, garlic and leek taste, with abundant meat soup savoury Aromatic.

As used herein, term benzyl mercaptan refers to benzene and mercaptan compound with following structural formula：

It is generally characterised in that with high intensity, strong green onion, sulphur, onion, garlic and horseradish fragrance, with peppermint and coffee Coffee smell.It is flavouring and is described as jerky, leek, horseradish, cabbage, tomato and coffee flavor.

As used herein, term butanethiol refers to butyl and mercaptan compound with following structural formula：

It is generally characterised in that with extremely fetor, smells extremely rancid smell, is commonly described as " skunk " gas Taste.Several key components of defence spraying in its structure with skunk are similar, but are not present in spraying in itself.Butanethiol Smell it is so strong so that in atmosphere under as little as 1/100000000th concentration, people's nose can be readily appreciated that it.Use the style Taste additive, it has abundant sulphur, plant, savoury, garlic and onion taste.

As used herein, term ethanethio refers to mercaptan and ethyl compound with following structural formula：

It is generally characterised in that with high intensity sulphur, skunk smell, with slightly fruity smell.

As used herein, term methyl mercaptan refers to the mercaptan with methyl with following structural formula：

It is generally characterised in that with extremely strong sulphur, rot cabbage, skunk fragrance.It is used in flavor enhancement and It is described as sulfur smoke, green onion taste and creamy taste, with reconciling the abundant depth of pure and fresh savoury before the cheese of surface-ripe.

As used herein, term furfuryl mercaptan refers to the C with following structural formula₅H₆OS：

It is generally characterised in that with extremely strong oiliness, fatty, baking coffee, sulphur skunk smell, with calcination Match smell.For in flavor enhancement, its be described as sulphur, baking coffee, calcination match sample, like rubber and slightly nut wind Taste, with egg and the abundant aromatic of savoury.

As used herein, term dithioglycol refers to the C with following structural formula₂H₆S₂：

It is generally characterised in that with very high strength sulphur, skunk smell, with slightly abundant smell.It is so strong, Recommend to hear in the case of 0.01% or lower concentration solution and smell it.

As used herein, term propyl group mercaptan refers to the mercaptan with propyl group with following structural formula：

It is generally characterised in that with high intensity green onion, natural gas, sugariness onion, cabbage smell.

As used herein, term thenyl mercaptan refers to the ring-type mercaptan with following structural formula：

It is generally characterised in that with high intensity baking coffee, taste with sweet and sour flavor.It is used as flavor enhancement, and wherein it has coffee Flavor.

As used herein, term gaultherolin refers to the organic ester with following structural formula：

It is generally characterised in that with strong unique Chinese ilex fragrance.Its flavor is sweet tea, salicylic acid and root beer sample, with Fragrance and face cream aromatic.It is used as the spices in food and drink, and in liniment, wherein it to be typically used as being directed to flesh The topical pharmaceutical products of meat, joint or soft tissue pain and inflammation.

As used herein, term methyl butenol refers to the class hemiterpene compound with following structural formula：

It is generally characterised in that with extremely strong, asphyxiating, malt draft fragrance.It is with high concentration from pinus contorta tree Release.

As used herein, term -2 methyl valeric acid methyl esters refers to the carboxylic acid with following structural formula：

It is generally characterised in that with moderate strength fruity, sugariness, berry, pineapple, apple, banana, jerky muskmelon and heat Strong fragrance.As the flavor additives useful in food, its taste is described as fruity, jerky apple, grape, bubble gum and pineapple sample 's.

As used herein, term methyl thiobutyrate refers to the methyl butyrate with sulphur atom rather than oxygen atom, under having State structural formula：

As used herein, term laurene (beta-myrcene) refers to the monoterpene with following structural formula：

Beta-myrcene is generally characterised in that with being described as hops, cloves sample, soil, jerky plant in a variety of ways Thing, citrus, fruity fragrance, with ardent, mango and the smell of peppermint aromatic.Various smells are slight differences in terms of main assembly Result.These flavors and smell are generally used for describing hemp.

As used herein, term γ-muurolene refers to the sequiterpene with following structural formula：

It is generally characterised in that with moderate strength oiliness, woody type and herb flavours fragrance.It is used for alfalfa kind Sub- wasp (Lucerne seed wasp) and the chemical communication system of the climing moth of European grape (European grapevine moth) In system.

As used herein, term nepetalactone refers to the bicyclic monoterpenoid with following structural formula：

It is generally characterised in that to have typically is considered as unacceptable valerian smell by people.It, which has, is similar to queen cat urine aodorization The compound of the component for being considered as simulation communication information element of agent.It is a kind of main attractant and stimulation in Catnip Agent, upon inhalation, it sees clearly the wild game behavior of many cats (that is, making their ' wandering ').Also its conduct is had shown that The active repellant of cockroach, and the test for yellow fever mosquito recently shows that it is than most popular synthesis pest repellant DEET The repellant that more effective 10 times of (N, N diethyl meta toluamide).

As used herein, term nerol refers to the monoterpene with following structural formula：

Nerol is generally characterised in that with strong fresh, moist seashore to sugariness rose scent.It is attar of rose, orange The composition of caul-fat and lavender oil.It is as the spices in cosmetics and as flavor enhancement.Its flavor have described as lemon, Bitter, jerky and fruity, with terpyridyl aromatic.

As used herein, term nerolidol refers to cis and trans isomers, has C₁₅H₂₆O sequiterpene.Instead Formula isomers has following structural formula：

Cis-isomer has following structural formula：

Nerolidol is generally characterised in that with gentle, the soft fragrance of a flower, apple, rose, jerky and citrus sample smell, companion There is wooden, wax aromatic.It is found in ginger, niaouli and lemongrass.In orange and other orange peels, it is as low-level Component is present.It is used as flavor enhancement and aromatic.Its flavor has described as the jerky, fragrance of a flower and wooden, with fruity mandarin orange Tangerine and muskmelon aromatic.It has antimycotic, anti-kala-azar and anti-malarial characteristic.It is also known that it can produce sedation.

As used herein, term neryl acetate refers to the acetic acid esters of nerol, has following structural formula：

It is generally characterised in that with the fragrance of a flower and fruity fragrance.

As used herein, term aldehyde C-9 refers to the aldehyde with following structural formula：

It is generally characterised in that with high intensity soap, wax, aldehyde, citrus smell, with fresh, slightly jerky, lemon Lemon skin sample aromatic and cucumber phat fat.It is the component of perfume, but it is existed in several natural oils.For flavor enhancement In, its taste is effervescency, aldehyde, citrus, cucumber and muskmelon pericarp, with thick potato and oiliness nut and coconut sample perfume Adjust.It has been identified as the compound for attracting mosquito.

As used herein, term n-nonanoic acid refers to the carboxylic acid with following structural formula：

It is generally characterised in that with high intensity is undesirable, corrupt, wax, dirt and cheese fragrance, with fermented milk products Aromatic.As cosmetics, spices and flavor enhancement, its flavor is fatty, wax and cheese, with gentle, sweet cream butter Background smell.

As used herein, term ocimenum refers to one group of isomerization hydrocarbon as monoterpene.α-ocimenum has following structures Formula：

For the disclosure, ocimenum can refer to any isomers in single purified form and/or combining form.α-sweet basil Alkene is generally characterised in that with moderate strength fruity, fragrance of a flower fragrance, with wet cloth smell.It is prematurity mango and mango ginger The contribution matter of the jerky smell of (Curcuma amada).It is used in the pickles of east.Being generally characterised in that for β-ocimenum has Moderate strength is ardent, jerky, terpene and woody odor, with plant aromatic.It is used as flavor enhancement, wherein its have it is jerky, ardent, Wooden flavor, with the fragrance of a flower and plant aromatic.It is the usual ingredients in flavor enhancement and perfume additive and much essential oil. β-cis-Ocimene is generally characterised in that with moderate strength warm nature, the fragrance of a flower, herbal medicine, sugariness, citrus sample fragrance.It is tea The component of the chemical communication system of weevil and bollworm.It has shown that some anti-oxidation characteristics.The spy of β-trans-ocimenum Sign is generally placed upon with gentle, draft, the sweet property of citrus, orange to citrus scented.Its Yong Yu Ash leaf maples stinkbug, a small number of beetles and intelligence In the chemical communication system of the small phytoseiid mite Predatory Mites of profit.

As used herein, term octanal refers to the aldehyde with following structural formula：

It, which is generally characterised in that, has the extremely strong jerky orange peel aromatic of aldehyde wax citrus.As flavouring, it is aldehyde Property and it is jerky, with skin taste, citrus, orange perfume adjust.

As used herein, term octanoic acid refers to the saturated fatty acid with following structural formula：

It is generally characterised in that with for most people repel extremely strongly old, corrupt, permeability, fatty, Wax, oiliness, cheese, sweat sample smell.It is used as the flavor enhancement of cosmetic surfactants and processed cheese.

As used herein, term p-cymene refers to the aromatic compounds related to monoterpene, has following structural formula：

P-cymene is generally characterised in that with the old breath of terpene, with orange to carrot smell, but synthesizes and umbrella is spent Hydrocarbon can have rosin sample smell.It has shown that antibiosis, anti-candida and AChE rejection characteristics.P-cymene is much essence The composition of oil, most commonly fennel seeds and thyme linaloe oil.

As used herein, term amyl butyrate refers to the ester of amylalcohol and butyric acid with following structural formula：

It is generally characterised in that the aftertaste smell with pears or apricot.

As used herein, term phellandrene refers to the cyclic monoterpenes with two kinds of isomers.α-phellandrene has in ring Two double bonds, there is following structural formula：

It is generally characterised in that with moderate strength terpene, citrus, herbal medicine, slightly jerky, black pepper sample smell.It is that flavor adds Add agent, wherein it is described as terpene, citrus lime flavored, with fresh jerky smell.β-phellandrene has one pair in ring Key, there is following structural formula：

It is generally characterised in that with moderate strength peppermint and slightly citrus taste smell, with slightly peppermint-rosin Smell.

As used herein, term phenylacetaldehyde refers to the aldehyde with phenyl, has following structural formula：

It is generally characterised in that extremely strength and infiltration excitant honey sample sugariness and jerky fragrance of a flower gas with passion fruit Taste.It is seen in buckwheat, chocolate and many other food and flowers.As additive, its flavor be honey, sugariness, the fragrance of a flower, Chocolate and cocoa flavored, with pungent aromatic.It has shown that certain antibiosis and antiasthmatic activity.

As used herein, term benzene ethyl mercaptan refers to the C with a variety of isomers₈H₁₀S.2- benzene ethyl mercaptans have following knots Structure formula：

Under the background of the disclosure, benzene ethyl mercaptan refers to any isomery in purifying compound and/or any form of mixtures Body.It is generally characterised in that with high-strength rubber smell.

As used herein, term phenylacetic acid refers to phenyl and carboxylic acid compound with following structural formula：

It is generally characterised in that with acid and sugariness, wax, civet, honey, rose, floral odor, with honeysuckle It is similar, with chocolate and the smell of tobacco.It is also used for sending out in sweetening treatment cosmetic.As flavouring, it has described as sweet tea Property, the fragrance of a flower, chocolate and honey flavour, with tobacco flavor.

As used herein, term phytol refers to the diterpene alcohol with following structural formula：

Phytol is generally characterised in that with gentle, the soft fragrance of a flower, face cream, jerky jasmine, raw tea type fragrance.Have shown that It prevents vitamin A teratogenesis.

As used herein, term australene refers to the bicyclic diterpene with following structural formula：

Australene it is generally relevant with to pine tree and their resin to be familiar with smell related.It is the main component of rosin simultaneously And many other essence oil from plant are largely seen, including in rosemary, Salvia japonica, eucalyptus and many essence oil from plant.Firpene can Medically it is used as expectorant and local antimicrobials.It easily propagates through blood-brain barrier, and wherein it serves as acetylcholine ester enzyme level Agent；That is, its activity for suppressing to destroy the chemical substance of information transmission molecule.This causes preferably to remember.Firpene also promotes vigilance Property and memory keep.Mainly due to the presence of firpene, so rosemary and Salvia japonica are regarded as " memory plant ".By they Concoction made from leaf has used thousands of years in traditional medicine, with holding and refresh memory.It is also that bronchus expands Open agent.60% intake, and relative bronchiectatic activity are shown to the pharmacokinetic study of the australene of suction in people. Smog seems the expansion in your lung and extremely quickly produces pleasant sensation, because the material of high percentage will enter blood flow and brain In.It also increases concentration degree, self-indulged and energy, and this is typically offseted with the presence of terpineol.Australene inhibited second Acetylcholinesterase, so as to show that there is effectiveness in terms of clinical treatment Alzheimer's (Alzheimer ' s disease).

As used herein, term nopinene refers to the monoterpene with following structural formula：

It is generally characterised in that with wooden-jerky pine tree sample smell.Nopinene be by forest-tree release it is a kind of most Abundant compound.It is one of two kinds of isomers of firpene (another kind is australene) and its shared similar characteristics.

As used herein, term propanethiol refers to the mercaptan with propyl, has following structural formula：

It is generally characterised in that the high intensity green onion smell with cabbage, sugariness onion and natural gas.It belongs to mercaptan Group.It is colourless, has strong aggressive smell.

As used herein, the flat modeling rattan element of term refers to the pentacyclic triterpene with following structural formula：

As used herein, term pulegone refers to the cyclic monoterpenes with following structural formula：

Pulegone is generally characterised in that with the peppermint-camphor smell and flavor being used in confectionery industry.Its Involve in the case of high dosage in hepatic injury.Pulegone is acetylcholinesteraseinhibitors inhibitors.Therefore, it makes destruction second The effect of the protein of phatidylcholine stops, and the acetylcholine is used for storing memory by brain.It can offset THC activity, described Activity causes relatively low levels of acetylcholine.Result be compared in THC with pulegone in the case of in you will forget Hold, in the case of independent THC, you will forget more contents.

As used herein, term Quercetin refers to the flavonoids with following structural formula：

It is generally characterized as polar growth element transport inhibitors.

As used herein, term retinol refers to the ring-type class diterpene alcohol with following structural formula：

It is a type of vitamin A, can change into other types of vitamin A.

As used herein, term rutin refers to the glucosides with following structural formula：

It is generally characterized as seeing the citrus flavonoid in many plants.

As used herein, term sabinene refers to the bicyclic diterpene with following structural formula enantiomter：

Sabinene is generally characterised in that with moderate strength warm nature, oiliness pepper, wooden, draft and pungent pine tree smell, With citrus smell.As flavouring, it is oiliness, citrus and tropical fruit (tree) taste.It sees Oak Tree, tea oil, black Hu In green pepper and it is the main component of carrot seed seed oil.

As used herein, term sabinene hydrate refers to the cyclic monoterpenes alcohol with following structural formula：

It is generally characterised in that with moderate strength, herbal medicine, nice and cool, peppermint, cineole, jerky and terpene smell, with Pungent aromatic.It is used as flavor additives useful and with nice and cool, peppermint, camphor, wooden jerky and oiliness flavor.It is also used for perfume (or spice) In material and cosmetics.

As used herein, term it is cis-sabinene hydrate refer to wherein alcohol groups be oriented in methyl rear sabinene hydration Thing structure.

It is generally characterised in that with moderate strength balsamic odour.

As used herein, term it is trans-sabinene hydrate refers to the sabinene hydration that wherein alcohol groups are oriented in front of methyl Thing structure.

It is generally characterised in that with moderate strength, more wooden, balsamic odour.

As used herein, term safranal refers to the monoterpene with aldehyde, and it has following structural formula：

It is generally characterized as be the fragrance for mainly resulting in safron component.Its flavor is wooden, medicine, phenol, pungent It is peppery and camphor, with fruity herbal medicine aromatic.Safranal be effective anticonvulsant, activator and its show compared with high anti-oxidation Cytotoxicity with free radical scavenging activity and for cancer cell.Also have shown that it has antidepression characteristic.

As used herein, term α-selinene refers to the bicyclic sequiterpene with following structural formula：

It is generally characterised in that the distinctive odor with amber.It is a kind of key component of celery oil.It has shown Show analgesia, anti-oxidant and antifungal activity, with antimicrobial potentiality.

As used herein, term α-sinensal refers to the type sesquiterpene with following structural formula：

It is generally characterised in that with moderate strength citrus orange, citrus aromes.Its flavor is orange, wax and succulence citrus Taste, with bitter skin aromatic.

As used herein, term β-sinensal refers to the type sesquiterpene with following structural formula：

It is generally characterised in that with moderate strength sugariness, fresh, wax, citrus, orange succulence smell.It is mainly used in perfume (or spice) In material.

As used herein, term cupreol refers to structure and phytosterol as cholesterol, and it has following structures Formula：

It is generally characterised in that with characteristic wax fragrance.It sees hickory nut, butter fruit, Pumpkin Seed, cashew nut, jade In rice bran oil and soybean.It has shown that inflammatory properties.

As used herein, term MF59 refers to the hydrocarbon triterpene with following structural formula：

It plays an important role in plant and animal sterol is synthesized.

As used herein, term Japanese yew diene refers to the tricyclic diterpene with following structural formula：

It is the intermediate of taxol biosynthesis.

As used herein, term dipentene glycol refers to the medicine that the mucus for being generally used for making the patient with breathing problem loosens Thing.It has following structural formula：

As used herein, term terpineol refers to the cyclic monoterpenes alcohol with following structural formula：

αisomer has isopropyl alcohol radical.α-terpineol is generally characterised in that with lilac, citrus or apple flower to acid Orange smell.It is widely used in perfumery.However, terpineol is generally seen in hemp with high firpene level.Therefore, the thorn of firpene Swash property fragrance and generally cover its smell.It is the submember of many essence oil from plant.It is also used to obtain fragrance in soap. In laboratory rat test, it makes locomitivity decline 45%.Display that it reaches deep sedation after inhalation.This can part Sofa locking (couch lock) effect of some hemps is explained, but it is generally not accompanied by body pleasant sensation.

As used herein, term terpinen-4-ols refer to the isomers with following structural formula of terpineol：

Terpinen-4-ols are generally characterised in that with desirable draft, pepper, woody odor and are used for business spices In.Terpinen-4-ols are used to obtain various Type of aroma in spices.It is considered to be the main active of tea oil.Its It is the compound of maximum concentration in myristic essential oil.Its exist in cypress, needle juniper berry, Ceylon's cardamom, marjoram, In thyme and the oil of a small number of other plants.Have shown that it serves as AChE inhibitor and antibiotic.

As used herein, term α-terpinenes refer to the cyclic monoterpenes with following structural formula：

It is generally characterised in that with refresh oneself, lemon-citrus scent.It is separated from cardamom and marjoram oil.

As used herein, term γ-terpinenes refer to the cyclic monoterpenes with following structural formula：

It is generally characterised in that with draft, citrus sugariness fragrance.It is commercially from tea tree oil extract.γ-terpinenes Antimicrobial property of the display for various human pathogens.Also its anti-oxidant, anti-inflammatory and anti-proliferate activity have been studied.

As used herein, term terpinolene/δ-terpinenes refer to the cyclic monoterpenes with prenyl, under it has State structural formula：

Terpinolene is generally characterised in that, with moderate strength herbal medicine fragrance, it has described as fresh, wooden, sweet tea Property and pine taste, with micro citrus taste.Its flavor is sugariness, wooden, terpene, lemon and bitter orange sample, with slightly herbal medicine and Fragrance of a flower aromatic.It is used as flavor enhancement and aromatic.It only uses more than 50,000 lbs per years in the U.S. in spices.Terpinol Alkene is used in soap, detergent, cream, lotion and perfume.

As used herein, term benzenethiol refers to the phenyl ring with sulphur atom, and it has following structural formula：

It is generally characterised in that with calcination rubber extremely strength, extremely persistently, smell rancid, pure fragrance.Its With high intensity, abundant, offensive, permeability, garlic, sulfur-containing aroma, with like rubber, undesirable rear taste.In flavouring Middle use, it is described as abundant, phenol nature and flavor road, with calcination rubber sulphury note.

As used herein, term absinthol refers to the bicyclic diterpene with ketone, and it has two kinds of diastereoisomeric forms, respectively From with two kinds of possible enantiomters.(-)-α-absinthol has following structural formula：

For the purpose of this disclosure, " absinthol " refers to any isomery in the form of mixtures of purified form or any ratio Change form.It is generally characterised in that with menthol sample smell.

As used herein, term thymol refers to the monoterpene phenol with following structural formula：

Thymol is generally characterised in that with unique, strong thyme flavor.It is commonly found in thyme linaloe oil, and In the form of the white crystalline material with desirable, aromatic odor and powerful antibacterial characteristics from silver-colored spot thyme (often claiming thyme) and The plant extract of various other species.Thymol is the Monoterpene amphyl of cymene.

As used herein, term alpha-tocopherol refers to the vitamin E form with following structural formula：

It is generally characterised in that with extremely gentle, slightly plant oil sample smell.Alpha-tocopherol is vitamin E compound A kind of most active component, and this organic substance be human body lipid phase in most powerful antioxidants.Alpha-tocopherol can have Effect ground make free radical deactivate and they can it is out of control before terminate chain reaction.

As used herein, term Tonka hendecanone refers to the twin nuclei with carbonyl and ester, and it has following knots Structure formula：

It is generally characterised in that with moderate strength, sugariness, pungent, face cream, the jerky fragrance of the wooden tobacco of Tonka.

As used herein, the term hendecanal refers to the aldehyde with following structural formula：

It is generally characterised in that with strong soap, aldehyde, wax and slightly effervesce orange citrus sample smell, with watermelon, Pineapple and caraway background smell.As additive, its flavor is wax, aldehyde and soapy flavor, with citrus smell and slightly Laundry detergent aromatic.The hendecanal is the usual ingredients of perfume.

As used herein, term valeral refers to the alkyl aldehydes with following structural formula：

It is generally characterised in that with fermented type, diffused, toast bread, fruity smell, with berry aromatic.As seasoning Agent, it has grape wine sample, fermentation, toast bread, cocoa flavor, with chocolate odors.

As used herein, term verdox refers to the cyclic ether with following structural formula：

It is generally characterised in that with moderate strength soil, fruity, jerky, herbal medicine, the old Odor of Wood cut.It is used for In spices and cosmetics.

As used herein, term ylangene refers to the ring-type sequiterpene with following structural formula：

It is generally characterised in that with pungent, fruity fragrance.It is the natural materials that are commonly found in grape wine and by Some plants are discharged.It has shown that both antibacterial characteristic and anti-oxidation characteristics.

As used herein, term umbelliferone refers to the class phenyl-propane with following structural formula：

It has been reported that it has anti-oxidation characteristics, and the ultraviolet light of several wavelength can be absorbed strongly.

As used herein, term vanillic aldehyde refers to the phenolic aldehyde with following structural formula：

It is generally characterised in that with desirable, sugariness fragrance and characteristic vanilla sample flavor.

As used herein, term " flavonoids " means a kind of secondary plant metabolin, and it has by two phenyl ring and miscellaneous Ring group into general 15 carbon backbone structure.Under the background of the disclosure, the example of flavonoids includes phenolic acid, class stilbene, dihydro extensively Flavonols, anthocyanin, anthocyanidin, polyphenol, tannic acid, flavones, flavan-3-alcohol, flavane -4- alcohol, flavane -3,4- glycol flavones Alcohol, phytochemicals, antioxidant, high isoflavonoid and contain any ketone including following compound：Flavonoids or life Species flavones, isoflavonoid, neoflavonoid or their derivative.

As used herein, term " cellulose " means with formula (C₆H₁₀O₅)_nOrganic compound.In the back of the body of the disclosure Under scape, phrase " generally not containing cellulose " be intend to distinguish between the purified components of naturally occurring plant (such as cannabis plants) with not Containing vegetable material (such as cellulose) through separating compound.

As used herein, term " mineral matter " means naturally occurring solid, inorganic, and has orderly atomic structure Material.Under the background of the disclosure, the example of mineral matter includes lithium.

The composition of the cannboid comprising purifying and the mineral matter of purifying is disclosed herein.In one embodiment, purify Mineral matter be lithium.In one embodiment, composition is substantially by the cannboid of the first purifying and the mineral matter group of purifying Into.

The composition of the cannboid comprising purifying and the terpene of purifying is disclosed herein.

In one embodiment, compositions disclosed herein includes and is selected from following terpene：7,8- dihydroionones, second Acyl group anisole, acetic acid, acetyl cedrene, anethole, anisole, benzaldehyde, bergaptene (α-cis-bergaptene) (α- Trans-bergaptene), bisabol (β-bisabol), borneol, butyric acid, cadinene (α-cadinene) (γ-cadinene), caffeol, Caffeic acid, camphor terpene, camphor, capsaicine, carene (Δ -3- carenes), carrotene, carvacrol, carvol, D-CARVONE, a left side Revolve carvol, carypohyllene (β-carypohyllene), caryophyllene oxide, castor essential oil, cedrene (eneα-cedar) (β-cedrene), Cedrene epoxides (eneα-cedar epoxides), cedrol, cembrene, chlorogenic acid, cinnamic acid (α-amyl group-cinnamic acid) (α-hexyl-cinnamic acid), cinnamic acid, cinnamyl alcohol, citronellal, citronellol, cryptone, curcumene (α-curcumene) (γ-curcumene), Capraldehyde, dehydrogenation vomiofliol, diallyl disulphide, dihydroactinidiolide, dimethyl disulfide, eicosane, elemi Alkene (beta-elemene), estragole, ethyl acetate, ethyl cinnamate, ethylmaltol, cineole/1,8- cineoles, eudesmol (α-eudesmol) (β-eudesmol) (γ-eudesmol), eugenol, Euphol, farnesene, farnesol, fenchol (β-turnip Alcohol), fenchone, geraniol, geranyl acetate, germacrene, germacrene B, guaiaci lignum -1 (10), 11- diene, guaiaci lignum Phenol, guaiene (α-guaiene), gurjunene (α-gurjunene), ayapanin, hexanal, caproic acid, Humuleno (α-humulus Oxalene) (β-Humuleno), ionol (3- oxygen-α-ionol) (β-ionol), irisone (α-ionone) (β- Irisone), ipsdienol, isoamyl acetate, isoamyl alcohol, isoamyl formate, isoborneol, different myrcenol, different Hu it is thin Lotus alcohol, isovaleric acid, isoprene, kahweol, lavender alcohol, limonene, gamma-Linolenic acid, linalool, longifolene, α-come into leaves Firpene, lycopene, menthol, methyl butyrate, 3- sulfydryls -2 methyl pentanal, mercaptan, beta -mercaptoethanol, TGA, allyl Base mercaptan, benzyl mercaptan, butanethiol, ethanethio, methyl mercaptan, furfuryl mercaptan, dithioglycol, propyl group mercaptan, thiophene first Base mercaptan, gaultherolin, methyl butenol, 2 methyl valeric acid methyl esters, methyl thiobutyrate, laurene (beta-myrcene), γ- Muurolene, nepetalactone, nerol, nerolidol, neryl acetate, aldehyde C-9, n-nonanoic acid, ocimenum, octanal, octanoic acid, to umbrella Flower hydrocarbon, amyl butyrate, phellandrene, phenylacetaldehyde, benzene ethyl mercaptan, phenylacetic acid, phytol, firpene, nopinene, propanethiol, it is flat modeling rattan element, Pulegone, retinol, sabinene, sabinene hydrate, cis-sabinene hydrate, trans-sabinene hydrate, safranal, α-snake Bed alkene, α-sinensal, β-sinensal, cupreol, MF59, Japanese yew diene, dipentene glycol, terpineol, terpinen-4-ols, α- Terpinenes, γ-terpinenes, terpinolene, benzenethiol, absinthol, thymol, alpha-tocopherol, Tonka hendecanone, 11 Aldehyde, valeral, verdox, ylangene, umbelliferone or vanillic aldehyde.

In one embodiment, compositions disclosed herein includes and is selected from following terpene：α-terpineol, bergaptene (α-cis-bergaptene) (α-trans-bergaptene), bisabol (β-bisabol), borneol, camphor, capsaicine, carvacrol, Carypohyllene (β-carypohyllene), caryophyllene oxide, cineole, cinnamic acid (α-amyl group-cinnamic acid) (α-hexyl-cinnamic acid), meat Cinnamic alcohol, citronellal, citronellol, ethyl cinnamate, cineole/1,8- cineoles, farnesol, fenchol (β-fenchol), acetic acid are fragrant Leaf ester, germacrene B, guaiene (α-guaiene), Humuleno (α-Humuleno) (β-Humuleno), ionol (3- Oxygen-α-ionol) (β-ionol), irisone (α-ionone) (alpha, beta-lonone), isoamyl acetate, isoamyl two It is alkene, kahweol, L-CARVONE, lavender alcohol, limonene, linalool, bergamio, cyanidenon, lycopene, thin Lotus alcohol, laurene (beta-myrcene), nerol, nerolidol, neryl acetate, p-cymene, phytol, firpene, it is flat modeling rattan element, Pulegone carrotene, retinol, dipentene glycol, terpineol, terpinol -4- alcohol, terpinolene, absinthol, thymol or Vanillic aldehyde.

In one embodiment, compositions disclosed herein includes cannabigerolic acid (CBGA), cannabigerolic acid list first Base ether (CBGAM), cannabigerol (CBG), cannabigerol monomethyl ether (CBGM), secondary cannabigerolic acid (Cannabigerovarinic Acid) (CBGVA), secondary cannabigerol (Cannabigerovarin) (CBGV), hemp chromene Sour (Cannabichromenic Acid) (CBCA), hemp chromene (CBC), secondary hemp chromene acid (Cannabichromevarinic Acid) (CBCVA), secondary hemp chromene (Cannabichromevarin) (CBCV), hemp Diphenoliac acid (Cannabidiolic Acid) (CBDA), cannabidiol (CBD), cannabidiol monomethyl ether (CBDM), hemp two Phenol-C₄(CBD-C₄), cannabidivarin sour (Cannabidivarinic Acid) (CBDVA), cannabidivarin (CBDV), Cannabidiorcol(CBD-C₁), tetrahydro-cannabinolic acid (Tetrahydrocannabinolic acid) A (THCA-A), four Hydrogen cannabinol B (THCA-B), THC (Tetrahydrocannabinol) (THC), tetrahydro-cannabinolic acid C₄ (THCA-C₄), THC C₄(THC-C₄), THCV it is sour (Tetrahydrocannabivarinic acid) (THCVA), THCV (Tetrahydrocannabivarin) (THCV), Tetrahydrocannabiorcolic acid(THCA-C₁)、Tetrahydrocannabiorcol(THC-C₁)、Δ⁷- cis-different THCV, Δ⁸- tetrahydrochysene Cannabinol (Δ 8-THCA), Δ⁸- THC (Δ⁸- THC), cannabicyclol it is sour (Cannabicyclolic acid) (CBLA), cannabicyclol (CBL), secondary cannabicyclol (Cannabicyclovarin) (CBLV), hemp Ai Ersong acid (Cannabielsoic acid) A (CBEA-A), hemp Ai Ersong acid B (CBEA-B), hemp Ai Ersong (CBE), cannabinol (Cannabinolic acid) (CBNA), cannabinol (CBN), cannabinol methyl ether (CBNM), cannabinol-C₄(CBN-C₄), it is secondary Cannabinol (CBV), Cannabino-C2 (CBN-C₂)、Cannabiorcol(CBN-C₁), cannabidiol (CBND), secondary hemp two Phenol (CBDV), dihydroxy cannabinol (CBT), 10- ethyoxyls -9- hydroxyls-Δ^6a- THC, 8,9- dihydroxy- Δ^6a(10a)- THC (8,9-Di-OH-CBT-C₅), dihydroxy time cannabinol (Cannabitriolvarin) (CBTV), Ethyoxyl-dihydroxy time cannabinol (CBTVE), dihydro hemp furans (DCBF), hemp furans (CBF), hemp benzo dihydro pyrrole Mutter ketone (Cannabichromanon) (CBCN), the pyrans cycloalkanes (Cannabicitran) (CBT) of hemp two, 10- oxygen- Δ^6a(10a)- THC (OTHC), Δ⁹- cis-THC (cis-THC), Cannabiripsol (CBR), 3,4, (OH- is different for 5,6- tetrahydrochysene -7- hydroxyl-alpha-α -2- trimethyl -9- n-propyl -2,6- methanol -2H-1- benzothiazole octyl- 5- methanol HHCV), trihydroxy-delta-9-Tetrahydrocannabinol (three OH-THC), kawain (Yangonin), EGCG Ester, dodecane -2E, 4E, 8Z, 10Z- tetraenoic acid isobutylamides or dodecane -2E, 4E- dienoic acid isobutylamides.

In one embodiment, compositions disclosed herein includes the cannboid of the first purifying, and it is selected from tetrahydrochysene hemp Phenol (THC), THCV (THCV), hemp chromene (CBC), hemp benzodihydropyrone (CBCN), cannabidiol (CBD), hemp Ai Ersong (CBE), cannabidivarin (CBDV), hemp furans (CBF), cannabicyclol (CBL), cannabinol (CBN), cannabidiol (CBND), dihydroxy cannabinol (CBT), secondary cannabinol (CBV) and different cannboid.

In one embodiment, the cannboid of the first purifying is selected from cannabigerolic acid (CBGA), cannabigerolic acid list first Base ether (CBGAM), cannabigerol (CBG), cannabigerol monomethyl ether (CBGM), secondary cannabigerolic acid (CBGVA), secondary hemp terpene Phenol (CBGV), hemp chromene sour (CBCA), hemp chromene (CBC), secondary hemp chromene sour (CBCVA), secondary hemp chromene (CBCV), Cannabidiolic acid (CBDA), cannabidiol (CBD), cannabidiol monomethyl ether (CBDM), cannabidiol-C₄(CBD-C₄), it is secondary big Numb diphenoliac acid (CBDVA), cannabidivarin (CBDV), Cannabidiorcol (CBD-C₁), tetrahydro-cannabinolic acid A (THCA- A), tetrahydro-cannabinolic acid B (THCA-B), THC (THC), tetrahydro-cannabinolic acid C₄(THCA-C₄), THC C₄ (THC-C₄), THCV sour (THCVA), THCV (THCV), Tetrahydrocannabiorcolic acid(THCA-C₁)、Tetrahydrocannabiorcol(THC-C₁)、Δ⁷- cis-different THCV, Δ⁸- tetrahydrochysene Cannabinol (Δ 8-THCA), Δ⁸- THC (Δ⁸- THC), it is cannabicyclol sour (CBLA), cannabicyclol (CBL), secondary big Numb ring phenol (CBLV), hemp Ai Ersong acid A (CBEA-A), hemp Ai Ersong acid B (CBEA-B), hemp Ai Ersong (CBE), hemp Phenolic acid (CBNA), cannabinol (CBN), cannabinol methyl ether (CBNM), cannabinol-C₄(CBN-C₄), secondary cannabinol (CBV), Cannabino-C₂(CBN-C₂)、Cannabiorcol(CBN-C₁), cannabidiol (CBND), cannabidivarin (CBDV), dihydroxy Base cannabinol (CBT), 10- ethyoxyls -9- hydroxyls-Δ^6a- THC, 8,9- dihydroxy-Δ^6a(10a)- THC (8,9-Di-OH-CBT-C₅), dihydroxy time cannabinol (CBTV), ethyoxyl-dihydroxy time cannabinol (CBTVE), dihydro hemp Furans (DCBF), hemp furans (CBF), hemp benzodihydropyrone (CBCN), the pyrans cycloalkanes (CBT) of hemp two, 10- oxygen- Δ^6a(10a)- THC (OTHC), Δ⁹- cis-THC (cis-THC), Cannabiripsol (CBR), 3,4, (OH- is different for 5,6- tetrahydrochysene -7- hydroxyl-alpha-α -2- trimethyl -9- n-propyl -2,6- methanol -2H-1- benzothiazole octyl- 5- methanol HHCV), trihydroxy-delta-9-Tetrahydrocannabinol (three OH-THC), kawain, Epigallo-catechin gallate (EGCG), dodecane- 2E, 4E, 8Z, 10Z- tetraenoic acid isobutylamides or dodecane -2E, 4E- dienoic acid isobutylamides

And the cannboid of the second purifying is selected from cannabigerolic acid (CBGA), cannabigerolic acid monomethyl ether (CBGAM), big Numb terpene phenol (CBG), cannabigerol monomethyl ether (CBGM), secondary cannabigerolic acid (CBGVA), secondary cannabigerol (CBGV), hemp Chromene acid (CBCA), hemp chromene (CBC), secondary hemp chromene sour (CBCVA), secondary hemp chromene (CBCV), cannabidiolic acid (CBDA), cannabidiol (CBD), cannabidiol monomethyl ether (CBDM), cannabidiol-C₄(CBD-C₄), cannabidivarin acid (CBDVA), cannabidivarin (CBDV), Cannabidiorcol (CBD-C₁), tetrahydro-cannabinolic acid A (THCA-A), tetrahydrochysene it is big Numb phenolic acid B (THCA-B), THC (THC), tetrahydro-cannabinolic acid C₄(THCA-C₄), THC C₄(THC-C₄)、 THCV acid (THCVA), THCV (THCV), Tetrahydrocannabiorcolic acid (THCA- C₁)、Tetrahydrocannabiorcol(THC-C₁)、Δ⁷- cis-different THCV, Δ⁸- tetrahydro-cannabinolic acid (Δ 8-THCA)、Δ⁸- THC (Δ⁸- THC), cannabicyclol sour (CBLA), cannabicyclol (CBL), secondary cannabicyclol (CBLV), hemp Ai Ersong acid A (CBEA-A), hemp Ai Ersong acid B (CBEA-B), hemp Ai Ersong (CBE), cannabinol (CBNA), cannabinol (CBN), cannabinol methyl ether (CBNM), cannabinol-C₄(CBN-C₄), secondary cannabinol (CBV), Cannabino-C₂(CBN-C₂)、Cannabiorcol(CBN-C₁), cannabidiol (CBND), cannabidivarin (CBDV), dihydroxy Base cannabinol (CBT), 10- ethyoxyls -9- hydroxyls-Δ^6a- THC, 8,9- dihydroxy-Δ^6a(10a)- THC (8,9-Di-OH-CBT-C₅), dihydroxy time cannabinol (CBTV), ethyoxyl-dihydroxy time cannabinol (CBTVE), dihydro hemp Furans (DCBF), hemp furans (CBF), hemp benzodihydropyrone (CBCN), the pyrans cycloalkanes (CBT) of hemp two, 10- oxygen- Δ^6a(10a)- THC (OTHC), Δ⁹- cis-THC (cis-THC), Cannabiripsol (CBR), 3,4, (OH- is iso- for 5,6- tetrahydrochysene -7- hydroxyl-alpha-α -2- trimethyl -9- n-propyl -2,6- methanol -2H-1- benzothiazole octyl- 5- methanol HHCV), trihydroxy-delta-9-Tetrahydrocannabinol (three OH-THC), kawain, Epigallo-catechin gallate (EGCG), dodecane- 2E, 4E, 8Z, 10Z- tetraenoic acid isobutylamides or dodecane -2E, 4E- dienoic acid isobutylamides.

The composition of the cannboid comprising purifying and the flavonoids of purifying is disclosed herein.

In one embodiment, compositions disclosed herein includes and is selected from following flavonoids：Phenolic acid, class stilbene, dihydro Flavonols, anthocyanin, anthocyanidin, polyphenol, tannic acid, flavones, flavan-3-alcohol, flavane -4- alcohol, flavane -3,4- glycol flavones Alcohol, phytochemicals, antioxidant, high isoflavonoid, phenylpropyl alcohol alkanes, phloroglucin cumarin, benzo dianthrone, steroids Glucosides, bioflavonoid, isoflavonoid and neoflavonoid.In one embodiment, compositions disclosed herein is included and is selected from Following flavonoids：Adenosine, adhyperforin, amentoflavone, anandamide, apiolin, horsetail Plain B, catechin (C), catechin 3- gallates (Cg), chlorogenic acid, Cichoric acid, caffeic acid, Daidezin, delphinidin, thorn Acankoreoside A, epicatechin 3- gallates (ECg), epicatechin, epicatechin, epigallocatechin, myricetin, grass Acid, pelargonidin, tannic acid, TF-3-G, theanine, theobromine, theophylline, tryptophan, tyrasamine, xanthine, coffee Coffee because, hemp flavine A, hemp flavine B, catechin (C), catechin 3- gallates (Cg), epicatechin 3- gallic acids Ester (ECg), epicatechin (epicatechin (EC)), epigallocatechin, epigallocatechin (EGC), epigallocatechin gallate Theine 3- gallates (EGCg), nutgall catechin (GC), nutgall catechin 3- gallates (GCg)), γ amino Butyric acid, genistein, ginkgo, ginsenoside, Quercetin, quercimentin or rutin.In one embodiment, it is disclosed herein Composition includes and is selected from following flavonoids：Caffeine, hemp flavine A, hemp flavine B, catechin (C), catechin 3- are not eaten Sub- acid esters (Cg), epicatechin 3- gallates (ECg), epicatechin (epicatechin (EC)), epigallocatechin, table Nutgall catechin (EGC), epigallocatechin 3- gallates (EGCg), nutgall catechin (GC), nutgall Theine 3- gallates (GCg)), gamma aminobutyric acid, genistein, ginkgo, ginsenoside, Quercetin, quercimentin or rue Glucoside.

The composition of the cannboid comprising purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include hemp chromene and the terpene selected from following at least one purifying：Linalool, borneol, elemene, laurene, nerolidol, plant Alcohol, terpinenes, borneolacetate or terpineol.

The composition of the cannboid comprising purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include cannabigerol and the terpene selected from following at least one purifying：Linalool, borneol, elemene, laurene, nerolidol, plant Alcohol, terpinenes, borneolacetate or terpineol.

The composition of the cannboid comprising purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include cannabinol and the terpene selected from following at least one purifying：Linalool, borneol, elemene, laurene, nerolidol, phytol, Terpinenes, borneolacetate or terpineol.

The composition of the cannboid comprising purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include THCV and selected from following at least one compound：Firpene, borneolacetate, limonene, carypohyllene and fragrant Chinese juniper Alkene.

The composition of the cannboid comprising purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include cannboid selected from THC and hemp chromene and selected from following at least one compound：Carypohyllene, firpene, acetic acid Norbornene ester, cineole and limonene.

The composition of the cannboid comprising purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include the cannboid selected from THC or THCV and at least one compound selected from limonene and carypohyllene.

The composition of the cannboid comprising purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include cannboid selected from THC or THCV and selected from limonene, terpinolene and pulegone at least A kind of compound.

The composition of the cannboid comprising purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include hemp chromene and at least one compound selected from linalool, laurene and terpineol.

The compound of the cannboid for including purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include cannabigerol and laurene.

The compound of the cannboid for including purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include cannabidiol and laurene.

The compound of the cannboid for including purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include cannabinol and at least one compound selected from linalool and terpineol.

The compound of the cannboid for including purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include THCV and at least one chemical combination selected from cineole, firpene, borneolacetate, limonene, carypohyllene and sabinene Thing.

The compound of the cannboid for including purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include selected from least one of THC and cannabidiol cannboid and selected from following at least one terpene：Carypohyllene, pinane Alkene, borneolacetate, cineole, limonene, pulegone, linalool, hypericin, pseudohypericin, Herba Hyperici Monogyni Element or anethole.

As used herein, term hypericin refers to the red anthraquinone derivative with following structural formula：

As used herein, term pseudohypericin refers to the hypericin with one or more alcohol radicals, has following knots Structure formula：

As used herein, term hyperforine refers to the isoprenylation phloroglucin with following structural formula and derived Thing：

The compound of the cannboid for including purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include THC or THCV and at least one compound selected from pulegone, cineole and anethole.

The compound of the cannboid for including purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include THC and laurene.

The compound of the cannboid for including purifying and the terpene of purifying is disclosed herein.In one embodiment, compound bag Include THCV and laurene.

Although the disclosure is described by reference to various exemplaries herein, it is to be appreciated that these realities Apply principle and application that scheme only illustrates the disclosure.It would be recognized by those skilled in the art that can be without departing from the scope of the invention Various modifications are carried out to exemplary.

Also, it should be appreciated that the various characteristics and/or feature of this paper different embodiments can be combined with each other.It is therefore to be understood that Without departing from the scope of the invention, numerous modifications can be carried out to illustrative embodiment and other arrangements can be designed.

It will be appreciated that regardless of whether statement, has implicit " about " before herein cited all numerical value.It will also be appreciated that The exact numerical used in description and claims forms other embodiment.Make efforts to ensure numerical value disclosed herein Accuracy.However, any measured value all can inherently containing see in its Correlative measurement method caused by standard deviation Some errors.

In addition, other embodiments of the disclosure are by the saying by consideration present invention disclosed herein for those skilled in the art Bright book shows and is apparent from putting into practice.Intent manual and embodiment are considered only as having exemplary, and wherein scope and spirit are by weighing Profit requires instruction.

In addition, in entire chapter the application, in the presence of specific molecular can be in the form of a variety of isomeries (such as stereoisomer), It should be appreciated that the disclosure covers each individual isomeric and any combination of mixture comprising those isomers.

Finally, it should be noted that as used in the specification and the appended claims, singulative " one (a/an) " and " (the) " refers to thing including a plurality of, unless clearly and being for certain limited to one refers to thing, and vice versa.Such as It is used herein, term " including (com prise/comprises/comprising) ", " contain (contain/contains/ Containing) ", " have (have/having) " and " including (include/includes/including) " is intended to right and wrong It is restricted, thus the narration to one or more projects be not excluded for it is replaceable or added to the one or more projects described Other similar items.

Embodiment

Following embodiments illustrate some aspects of foregoing invention.They are not construed as the gamut of the limitation present invention.

Embodiment 1

By the way that cannabis plant material is inserted in freezer unit, cannabis plant material is cooled to -20C, continue 24 hours.So , will be cold with cold ethanol (every gram of cannabis plant material 2mL-20C ethanol) afterwards by stirring mixture vegetable material and ethanol 3 minutes But twice, liquid then is decanted from mixture in vegetable material wet-milling.The each several part of the ethanol containing decantation is merged, and in -20C Lower cooling 24 hours.Removed and precipitated by gravity filtration.Ethanol is removed from filtrate by evaporation, so as to leave amber oil.

Oil is dissolved in ethanol (10-100mg/mL).This solution is injected equipped with the overcritical of ethylpyridine post In fluid chromatograph.Collect pure fraction and by LC-MS, multiple-reaction monitoring transition, full scan detection, photodiode array Detect with Evaporative light scattering detector to analyze to assess purity.

Embodiment 2

By the way that cannabis plant material is inserted in freezer unit, cannabis plant material is cooled to -20C, continue 24 hours.Will The vegetable material of cooling is ground into diameter about 2mm particle.Particle is transferred in cylinder and is connected to supercritical fluid and is carried Device is taken to extract cannboid and flavonoids.Collect the extraction material in amber oil form.Oil is dissolved in ethanol (10- In 100mg/mL).This solution is injected equipped with the supercritical fluid chromatograph of ethylpyridine post.Collect pure fraction and Analyzed by LC-MS, multiple-reaction monitoring transition, full scan detection, photodiode array detection and Evaporative light scattering detector To assess purity.

Embodiment 3

By combining following components come compositions formulated：THCV(1g)；CBG(1g)；CBC(1g)；THC(2g)；And CBD (4g)；B- carypohyllenes (0.2)；Linalool (0.005g)；Limonene (0.001g)；Pulegone (Pilegone) (0.005g)； With Humuleno (0.005g).

Embodiment 4

By combining following components come compositions formulated：THCV(1g)；CBG(1g)；CBC(2g)；THC(1g)；And CBD (2g)；1,8- cineoles (0.005g)；A- firpenes (0.005g)；With limonene (0.001g).

Embodiment 5

By combining following components come compositions formulated：CBG(1g)；CBC(2g)；THC(4g)；With CBD (1g)；1,8- eucalyptus Set brain (0.0025g)；A- firpenes (0.0025g)；B- laurenes (0.001g)；With limonene (0.001g).

Embodiment 6

By combining following components come compositions formulated：THCV(2g)；CBG(1g)；CBC(1g)；THC 3g)；And CBD (1g)；B- carypohyllenes (0.0025g)；Linalool (0.001g)；1,8- cineoles (0.0025g)；B- laurenes (0.0025g)； Limonene (0.001g)；With pulegone (0.001g).

Embodiment 7

By combining following components come compositions formulated：CBG(1g)；THC(5g)；With CBD (1g)；B- carypohyllenes (0.05g)；Linalool (0.01g)；B- laurenes (0.001g)；Limonene (0.001g)；Pulegone (0.01g)；And humulus grass Alkene (0.01g).

Claims

1. a kind of composition, it is included：

The cannboid of first purifying；With

Wherein described composition generally not containing cellulose.

2. composition as claimed in claim 1, it includes the mineral matter of purifying.

3. composition as claimed in claim 2, wherein the mineral matter of the purifying is lithium.

4. composition as claimed in claim 2, it is substantially made up of the cannboid of the first purifying and the mineral matter of purifying.

5. composition as claimed in claim 1, it includes the terpene of purifying.

6. composition as claimed in claim 5, wherein the terpene is selected from 7,8- dihydroionones, navatone, second Acid, acetyl cedrene, anethole, anisole, benzaldehyde, bergaptene (α-cis-bergaptene) (α-trans-bergamot Alkene), bisabol (β-bisabol), borneol, butyric acid, cadinene (α-cadinene) (γ-cadinene), caffeol, caffeic acid, camphor Terpene, camphor, capsaicine, carene (Δ -3- carenes), carrotene, carvacrol, carvol, D-CARVONE, L-CARVONE, stone Bamboo alkene (β-carypohyllene), caryophyllene oxide, castor essential oil, cedrene (eneα-cedar) (β-cedrene), cedrene epoxy Compound (eneα-cedar epoxides), cedrol, cembrene, chlorogenic acid, cinnamic acid (α-amyl group-cinnamic acid) (α-hexyl-Chinese cassia tree Aldehyde), cinnamic acid, cinnamyl alcohol, citronellal, citronellol, cryptone, curcumene (α-curcumene) (γ-curcumene), capraldehyde, dehydrogenation urge Mitoridine wood alcohol, diallyl disulphide, dihydroactinidiolide, dimethyl disulfide, eicosane, elemene (β-elemi Alkene), estragole, ethyl acetate, ethyl cinnamate, ethylmaltol, cineole/1,8- cineoles, eudesmol (α-eucalyptus oil Alcohol) (β-eudesmol) (γ-eudesmol), eugenol, Euphol, farnesene, farnesol, fenchol (β-fenchol), fenchone, Geraniol, geranyl acetate, germacrene, germacrene B, guaiaci lignum -1 (10), 11- diene, guaiacol, guaiaci lignum Alkene (α-guaiene), gurjunene (α-gurjunene), ayapanin, hexanal, caproic acid, Humuleno (α-Humuleno) (β- Humuleno), ionol (3- oxygen-α-ionol) (β-ionol), irisone (α-ionone) (β-violet Ketone), it is ipsdienol, isoamyl acetate, isoamyl alcohol, isoamyl formate, isoborneol, different myrcenol, isopulegol, different Valeric acid, isoprene, kahweol, lavender alcohol, limonene, gamma-Linolenic acid, linalool, longifolene, α-longipinene, kind Lycopene, menthol, methyl butyrate, 3- sulfydryls -2 methyl pentanal, mercaptan, beta -mercaptoethanol, TGA, allyl sulfhydrate, Benzyl mercaptan, butanethiol, ethanethio, methyl mercaptan, furfuryl mercaptan, dithioglycol, propyl group mercaptan, thenyl mercaptan, Gaultherolin, methyl butenol, 2 methyl valeric acid methyl esters, methyl thiobutyrate, laurene (beta-myrcene), γ-cananga oil Alkene, nepetalactone, nerol, nerolidol, neryl acetate, aldehyde C-9, n-nonanoic acid, ocimenum, octanal, octanoic acid, p-cymene, fourth Sour pentyl ester, phellandrene, phenylacetaldehyde, benzene ethyl mercaptan, phenylacetic acid, phytol, firpene, nopinene, propanethiol, it is flat modeling rattan element, come into leaves it is thin Lotus ketone, retinol, rutin, sabinene, sabinene hydrate, cis-sabinene hydrate, trans-sabinene hydrate, safranal, α- Selinene, α-sinensal, β-sinensal, cupreol, MF59, Japanese yew diene, dipentene glycol, terpineol, terpinen-4-ols, α-terpinenes, γ-terpinenes, terpinolene, benzenethiol, absinthol, thymol, alpha-tocopherol, Tonka hendecanone, 11 Aldehyde, valeral, verdox, ylangene, umbelliferone or vanillic aldehyde.

7. composition as claimed in claim 5, wherein the terpene is selected from α-terpineol, bergaptene (α-cis-bergamot Alkene) (α-trans-bergaptene), bisabol (β-bisabol), borneol, camphor, capsaicine, carvacrol, carypohyllene (β-China pink Alkene), caryophyllene oxide, cineole, cinnamic acid (α-amyl group-cinnamic acid) (α-hexyl-cinnamic acid), cinnamyl alcohol, citronellal, perfume (or spice) Thatch alcohol, ethyl cinnamate, cineole/1,8- cineoles, farnesol, fenchol (β-fenchol), geranyl acetate, germacrene B, guaiene (α-guaiene), Humuleno (α-Humuleno) (β-Humuleno), ionol (3- oxygen-α-ionol) (β-ionol), irisone (α-ionone) (alpha, beta-lonone), isoamyl acetate, isoprene, kahweol, a left side Revolve carvol, lavender alcohol, limonene, linalool, bergamio, cyanidenon, lycopene, menthol, laurene (β- Laurene), nerol, nerolidol, neryl acetate, p-cymene, phytol, firpene, flat modeling rattan element, retinol, be hydrated terpene Product, terpineol, terpinol -4- alcohol, terpinolene, absinthol, thymol or vanillic aldehyde.

8. composition as claimed in claim 5, it includes cannabigerolic acid (CBGA), cannabigerolic acid monomethyl ether (CBGAM), cannabigerol (CBG), cannabigerol monomethyl ether (CBGM), secondary cannabigerolic acid (CBGVA), secondary cannabigerol (CBGV), hemp chromene sour (CBCA), hemp chromene (CBC), secondary hemp chromene sour (CBCVA), secondary hemp chromene (CBCV), big Numb diphenoliac acid (CBDA), cannabidiol (CBD), cannabidiol monomethyl ether (CBDM), cannabidiol-C₄(CBD-C₄), secondary hemp Diphenoliac acid (CBDVA), cannabidivarin (CBDV), Cannabidiorcol (CBD-C₁), tetrahydro-cannabinolic acid A (THCA-A), Tetrahydro-cannabinolic acid B (THCA-B), THC (THC), tetrahydro-cannabinolic acid C₄(THCA-C₄), THC C₄ (THC-C₄), THCV sour (THCVA), THCV (THCV), Tetrahydrocannabiorcolic acid(THCA-C₁)、Tetrahydrocannabiorcol(THC-C₁), cis-different THCVs of δ -7-, Δ⁸- tetrahydrochysene Cannabinol (Δ 8-THCA), Δ⁸- THC (Δ⁸- THC), it is cannabicyclol sour (CBLA), cannabicyclol (CBL), secondary big Numb ring phenol (CBLV), hemp Ai Ersong acid A (CBEA-A), hemp Ai Ersong acid B (CBEA-B), hemp Ai Ersong (CBE), hemp Phenolic acid (CBNA), cannabinol (CBN), cannabinol methyl ether (CBNM), cannabinol-C₄(CBN-C₄), secondary cannabinol (CBV), Cannabino-C₂(CBN-C₂)、Cannabiorcol(CBN-C₁), cannabidiol (CBND), cannabidivarin (CBDV), dihydroxy Base cannabinol (CBT), 10- ethyoxyls -9- hydroxyls-Δ^6a- THC, 8,9- dihydroxy-Δ^6a(10a)- THC (- the OH-CBT-C of 8,9- bis-₅), dihydroxy time cannabinol (CBTV), ethyoxyl-dihydroxy time cannabinol (CBTVE), dihydro hemp Furans (DCBF), hemp furans (CBF), hemp benzodihydropyrone (CBCN), the pyrans cycloalkanes (CBT) of hemp two, 10- oxygen- Δ^6a(10a)- THC (OTHC), Δ⁹- cis-THC (cis-THC), Cannabiripsol (CBR), 3,4, (OH- is different for 5,6- tetrahydrochysene -7- hydroxyl-alpha-α -2- trimethyl -9- n-propyl -2,6- methanol -2H-1- benzothiazole octyl- 5- methanol HHCV), trihydroxy-delta-9-Tetrahydrocannabinol (three OH-THC), different cannboid and Epigallo-catechin gallate (EGCG).

9. composition as claimed in claim 8, wherein the cannboid of first purifying is selected from THC (THC), four Hydrogen time cannabinol (THCV), hemp chromene (CBC), hemp benzodihydropyrone (CBCN), cannabidiol (CBD), hemp Chinese mugwort That loose (CBE), cannabidivarin (CBDV), hemp furans (CBF), cannabicyclol (CBL), cannabinol (CBN), cannabidiol (CBND), dihydroxy cannabinol (CBT), secondary cannabinol (CBV) and different cannboid.

10. composition as claimed in claim 9, it includes the cannboid selected from the first following purifying：Cannabigerolic acid (CBGA), cannabigerolic acid monomethyl ether (CBGAM), cannabigerol (CBG), cannabigerol monomethyl ether (CBGM), secondary hemp Terpene phenol acid (CBGVA), secondary cannabigerol (CBGV), hemp chromene sour (CBCA), hemp chromene (CBC), secondary hemp chromene acid (CBCVA), secondary hemp chromene (CBCV), cannabidiolic acid (CBDA), cannabidiol (CBD), cannabidiol monomethyl ether (CBDM), cannabidiol-C₄(CBD-C₄), cannabidivarin sour (CBDVA), cannabidivarin (CBDV), Cannabidiorcol (CBD-C₁), tetrahydro-cannabinolic acid A (THCA-A), tetrahydro-cannabinolic acid B (THCA-B), THC (THC), tetrahydrochysene hemp Phenolic acid C₄(THCA-C₄), THC C₄(THC-C₄), THCV sour (THCVA), THCV (THCV), Tetrahydrocannabiorcolic acid(THCA-C₁)、Tetrahydrocannabiorcol(THC-C₁), δ -7- it is suitable Formula-different THCV, Δ⁸- tetrahydro-cannabinolic acid (Δ 8-THCA), Δ⁸- THC (Δ⁸- THC), cannabicyclol Sour (CBLA), cannabicyclol (CBL), secondary cannabicyclol (CBLV), hemp Ai Ersong acid A (CBEA-A), hemp Ai Ersong acid B (CBEA-B), hemp Ai Ersong (CBE), cannabinol (CBNA), cannabinol (CBN), cannabinol methyl ether (CBNM), hemp Phenol-C₄(CBN-C₄), secondary cannabinol (CBV), Cannabino-C₂(CBN-C₂)、Cannabiorcol(CBN-C₁), cannabidiol (CBND), cannabidivarin (CBDV), dihydroxy cannabinol (CBT), 10- ethyoxyls -9- hydroxyls-Δ^6a- THC, 8, 9- dihydroxy-Δ^6a(10a)- the THC (- OH-CBT-C of 8,9- bis-₅), dihydroxy time cannabinol (CBTV), ethyoxyl-dihydroxy Base time cannabinol (CBTVE), dihydro hemp furans (DCBF), hemp furans (CBF), hemp benzodihydropyrone (CBCN), The pyrans cycloalkanes (CBT) of hemp two, 10- oxygen-Δ^6a(10a)- THC (OTHC), Δ⁹- cis-THC (cis- THC), Cannabiripsol (CBR), 3,4,5,6- tetrahydrochysene -7- hydroxyl-alpha-α -2- trimethyl -9- n-propyl -2,6- methanol - 2H-1- benzothiazole octyl- 5- methanol (the different HHCV of OH-), trihydroxy-delta-9-Tetrahydrocannabinol (three OH-THC), kawain, different hemp Element, Epigallo-catechin gallate (EGCG), dodecane -2E, 4E, 8Z, 10Z- tetraenoic acid isobutylamides or dodecane -2E, 4E- dienoic acid isobutylamides；And

Cannboid selected from the second following purifying：It is cannabigerolic acid (CBGA), cannabigerolic acid monomethyl ether (CBGAM), big Numb terpene phenol (CBG), cannabigerol monomethyl ether (CBGM), secondary cannabigerolic acid (CBGVA), secondary cannabigerol (CBGV), hemp Chromene acid (CBCA), hemp chromene (CBC), secondary hemp chromene sour (CBCVA), secondary hemp chromene (CBCV), cannabidiolic acid (CBDA), cannabidiol (CBD), cannabidiol monomethyl ether (CBDM), cannabidiol-C₄(CBD-C₄), cannabidivarin acid (CBDVA), cannabidivarin (CBDV), Cannabidiorcol CBD-C₁), tetrahydro-cannabinolic acid A (THCA-A), tetrahydrochysene it is big Numb phenolic acid B (THCA-B), THC (THC), tetrahydro-cannabinolic acid C₄(THCA-C₄), THC C₄(THC-C₄)、 THCV acid (THCVA), THCV (THCV), Tetrahydrocannabiorcolic acid (THCA- C₁)、Tetrahydrocannabiorcol(THC-C₁), cis-different THCVs of δ -7-, Δ⁸- tetrahydro-cannabinolic acid (Δ 8-THCA)、Δ⁸- THC (Δ⁸- THC), cannabicyclol sour (CBLA), cannabicyclol (CBL), secondary cannabicyclol (CBLV), hemp Ai Ersong acid A (CBEA-A), hemp Ai Ersong acid B (CBEA-B), hemp Ai Ersong (CBE), cannabinol (CBNA), cannabinol (CBN), cannabinol methyl ether (CBNM), cannabinol-C₄(CBN-C₄), secondary cannabinol (CBV), Cannabino-C₂(CBN-C₂)、Cannabiorcol(CBN-C₁), cannabidiol (CBND), cannabidivarin (CBDV), dihydroxy Base cannabinol (CBT), 10- ethyoxyls -9- hydroxyls-Δ^6a- THC, 8,9- dihydroxy-Δ^6a(10a)- THC (- the OH-CBT-C of 8,9- bis-₅), dihydroxy time cannabinol (CBTV), ethyoxyl-dihydroxy time cannabinol (CBTVE), dihydro hemp Furans (DCBF), hemp furans (CBF), hemp benzodihydropyrone (CBCN), the pyrans cycloalkanes (CBT) of hemp two, 10- oxygen- Δ^6a(10a)- THC (OTHC), Δ⁹- cis-THC (cis-THC), Cannabiripsol (CBR), 3,4, (OH- is different for 5,6- tetrahydrochysene -7- hydroxyl-alpha-α -2- trimethyl -9- n-propyl -2,6- methanol -2H-1- benzothiazole octyl- 5- methanol HHCV), trihydroxy-delta-9-Tetrahydrocannabinol (three OH-THC), kawain, different cannboid, EGCG Ester, dodecane -2E, 4E, 8Z, 10Z- tetraenoic acid isobutylamides or dodecane -2E, 4E- dienoic acid isobutylamides.

11. composition as claimed in claim 1, it includes the flavonoids of purifying.

12. composition as claimed in claim 11, wherein the flavonoids is selected from phenolic acid, class stilbene, flavanonol, anthocyanin Element, anthocyanidin, polyphenol, tannic acid, flavones, flavan-3-alcohol, flavane -4- alcohol, flavane -3,4- glycol flavonols, class stilbene, plant Chemical substance, antioxidant, high isoflavonoid, phenylpropyl alcohol alkanes, phloroglucin cumarin, phenolic acid, benzo dianthrone, steroids sugar Glycosides, bioflavonoid, isoflavonoid and neoflavonoid.

13. composition as claimed in claim 11, wherein the flavonoids is selected from adenosine, adhyperforin, amentotaxus It is biflavone, anandamide, apiolin, hemp flavine B, catechin (C), catechin 3- gallates (Cg), green Ortho acid, Cichoric acid, caffeic acid, Daidezin, delphinidin, eleutheroside, epicatechin 3- gallates (ECg), table catechu Element, epicatechin, epigallocatechin, myricetin, oxalic acid, pelargonidin, tannic acid, TF-3-G, tea Propylhomoserin, theobromine, theophylline, tryptophan, tyrasamine, xanthine, caffeine, hemp flavine A, hemp flavine B, catechin (C), catechu Plain 3- gallates (Cg), epicatechin 3- gallates (ECg), epicatechin (epicatechin (EC)), epi-nutgall Catechin, epigallocatechin (EGC), epigallocatechin 3- gallates (EGCg), nutgall catechin (GC), Nutgall catechin 3- gallates (GCg)), gamma aminobutyric acid, genistein, ginkgo, ginsenoside, Quercetin, oak Element or rutin.

14. composition as claimed in claim 11, wherein the flavonoids of the purifying is selected from caffeine, hemp flavine A, hemp Flavine B, catechin (C), catechin 3- gallates (Cg), epicatechin 3- gallates (ECg), epicatechin (table Catechin (EC)), epigallocatechin, epigallocatechin (EGC), epigallocatechin 3- gallates (EGCg), nutgall catechin (GC), nutgall catechin 3- gallates (GCg)), gamma aminobutyric acid, genistein, Ginkgo, ginsenoside, Quercetin, quercimentin or rutin.

15. composition as claimed in claim 1, its include hemp chromene and selected from linalool, borneol, elemene, laurene, Nerolidol, phytol, terpinolene, borneolacetate, terpineol at least one purifying terpene.

16. composition as claimed in claim 1, its include cannabigerol and selected from linalool, borneol, elemene, laurene, Nerolidol, phytol, terpinolene, borneolacetate, terpineol at least one purifying terpene.

17. composition as claimed in claim 1, it includes cannabinol and selected from linalool, borneol, elemene, laurene, orange The flower tertiary alcohol, phytol, terpinolene, borneolacetate, at least one compound of terpineol.

18. composition as claimed in claim 1, it includes THCV and selected from firpene, borneolacetate, lemon At least one compound of alkene, carypohyllene and sabinene.

19. composition as claimed in claim 1, it is comprising the cannboid selected from THC and hemp chromene and selected from stone Bamboo alkene, firpene, borneolacetate, cineole, limonene, carypohyllene, firpene, at least one compound of borneolacetate.

20. composition as claimed in claim 1, it includes cannboid and choosing selected from THC or THCV From at least one compound of limonene and carypohyllene.

21. composition as claimed in claim 1, it includes cannboid and choosing selected from THC or THCV From limonene, terpinolene, pulegone at least one compound.

22. compound as claimed in claim 1, it include hemp chromene and selected from linalool, laurene, terpineol at least A kind of compound.

23. compound as claimed in claim 1, it includes cannabigerol and laurene.

24. compound as claimed in claim 1, it includes cannabidiol and laurene.

25. compound as claimed in claim 1, it includes cannabinol and at least one chemical combination selected from linalool, terpineol Thing.

26. compound as claimed in claim 1, it includes THCV and selected from cineole, firpene, acetic acid borneol Ester, limonene, at least one compound of carypohyllene and sabinene.

27. compound as claimed in claim 1, it includes at least one cannboid selected from THC or cannabidiol With selected from carypohyllene, firpene, borneolacetate, cineole, limonene, pulegone, linalool, hypericin, false spun gold Peach element, hyperforine, at least one terpene of anethole.

28. compound as claimed in claim 1, it includes THC or THCV and selected from pulegium Ketone, cineole, at least one compound of anethole.

29. compound as claimed in claim 1, it includes THC and laurene.

30. compound as claimed in claim 1, it includes THCV and laurene.