CN107375065B - A kind of composition and preparation method with maintenance and recovery skin Tiny ecosystem effect - Google Patents
A kind of composition and preparation method with maintenance and recovery skin Tiny ecosystem effect Download PDFInfo
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- CN107375065B CN107375065B CN201710604164.9A CN201710604164A CN107375065B CN 107375065 B CN107375065 B CN 107375065B CN 201710604164 A CN201710604164 A CN 201710604164A CN 107375065 B CN107375065 B CN 107375065B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The present invention relates to a kind of with the composition and preparation method thereof for safeguarding and restoring the effect of skin Tiny ecosystem, it is characterised in that including following components: mass ratio is trunk natural sap, fresh squeezing fruit syrup, special carbohydrate and the different malt of 10-40:6-30:1-5:3-6；The trunk natural sap is mixed by white birch myron, maple juice 5 ~ 9:1 in mass ratio；The fruit syrup be Fresh Cucumber Juice, guava juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice, Chinese gooseberry fruit juice etc. quality compare mixture；The sugar is that one of gossypose, oligofructose, galactooligosaccharide, inulin or their any quality compare mixture.Composition prepared by the present invention has the effect of generation that is anti-inflammatory, promoting antibacterial peptide, can safeguard and restore the health of skin Tiny ecosystem.
Description
Technical field
It is the present invention relates to cosmetic technical field, in particular to a kind of with the group for safeguarding and restoring the effect of skin Tiny ecosystem
Close object and preparation method thereof.
Background technique
In recent years, the natural origin raw material of food and health products trade is gradually applied to cosmetic field, some direct
The myron obtained from trunk has been used as beverage and health beverages deep by consumer because being rich in minerals and microelement
Like.The fruit juice of fresh squeezing is all liked by consumer all the time rich in ingredients such as vitamins.These myrons and fruit juice
Source is relatively natural, environmental protection, rich in much to the ingredient of skin beneficiating, pursuing safety, natural, health skin care in current social
Under trend, cosmetics can be applied to and had very important significance.
Skin can be resisted a degree of physical, chemically or biological thorn as the outermost protective barrier of body
Swash.The water content of stratum corneum of skin maintains the full and normal physiological activity of health of skin between 10% ~ 30%.In addition,
A large amount of microorganism is also settled down on the surface of skin, forms skin Tiny ecosystem barrier.The flora of skin surface is divided into resident bacteria
With bacterium of staying temporarily, harmless symbiosis is shown as under normal circumstances, but when the relationship of this balance is broken, skin
Function will disorder, cause body disease occur.
Natural myron and fruit juice provides balanced nutrition, has front promotion effect well to the resident microorganism of skin
It answers, helps firm skin Tiny ecosystem barrier, promote skin health.
Summary of the invention
The technical problem to be solved by the present invention is to provide a kind of with the composition for safeguarding and restoring the effect of skin Tiny ecosystem
And preparation method thereof.
In order to solve the above technical problems, the invention adopts the following technical scheme: a kind of have maintenance and restore the micro- life of skin
The composition of state effect, it is characterised in that including following components: mass ratio is the trunk natural juice of 10-40:6-30:1-5:3-6
Liquid, fresh squeezing fruit and vegetable juice, carbohydrate and different malt；The trunk natural sap is mixed by white birch myron, maple juice 5-9:1 in mass ratio
It forms；The fresh squeezing fruit and vegetable juice is Fresh Cucumber Juice, guava juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice, Chinese gooseberry fruit juice
Etc. quality compare mixture；The carbohydrate be one of gossypose, oligofructose, galactooligosaccharide, inulin or they
Any quality compares mixture.
As a preference of the present invention, birch skin brain mass content >=0.14% in the white birch myron, in the maple juice
Maple sugar mass content >=3.5%, content of vitamin E >=0.5mg/100g in the Fresh Cucumber Juice, the polyphenol in the guava juice
Content >=143mg/100g, potassium content >=230mg/100ml in the coconut water, the superoxides discrimination in the Blackthorn pear fruit-juice
Change enzyme >=450u/g, general flavone >=4.1mg/100g in the sea buckthorn juice, the vitamin C in the Chinese gooseberry fruit juice
Content >=300mg/100g.
The trunk natural sap that white birch myron and maple juice of the present invention are composed can help skin to resist
Oxide has anti-inflammatory efficacy, Fresh Cucumber Juice, guava juice, Chinese gooseberry fruit juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice etc.
The fresh fruit and vegetable juice and special carbohydrate of squeezing can promote the synthesis of antibacterial peptide to reach the balance of the micro- raw peptide of skin.
The trunk natural sap is mixed by white birch myron, maple juice 5-9:1 in mass ratio, and white birch myron source is
Wild silver birch in the domestic virgin forest in the big Xiaoxinanlin Mountains in China, it is annual to collect season as annual May, it drills on trunk
It is collected after being drawn afterwards with conduit, freezes stand-by, birch skin brain mass content >=0.14% after collection in 6 hours in -20 DEG C of iceboxs；
Maple juice is Canadian import, is collected after boring conduit extraction on sugar maple tree trunk annual April, after collection in 6 hours-
Stand-by, maple sugar mass content >=3.5% is freezed in 20 DEG C of iceboxs.
The fresh squeezing fruit and vegetable juice is Fresh Cucumber Juice, guava juice, Chinese gooseberry fruit juice, coconut water, Blackthorn pear fruit-juice, fructus hippophae
Juice etc. quality than mixture, wherein Fresh Cucumber Juice (content of vitamin E >=0.5mg/100g), guava juice (polyphenol content >=
143mg/100g), Chinese gooseberry fruit juice (Vitamin C content >=300mg/100g) is direct mechanical expression institute after fresh fruit peeling
, coconut water (potassium content >=230mg/100ml) be broken shell after pour out gained, Blackthorn pear fruit-juice (superoxide dismutase >=450u/
G), sea buckthorn juice (general flavone >=4.1mg/100g) is obtained by direct mechanical expression, the above fruit and vegetable juice squeezed respectively by fresh fruit after 6
It is freezed in -20 DEG C of iceboxs in hour stand-by；Cucumber is produced by Zhejiang, Curcurbitaceae cucumber plants, fruit color in glossy dark green or
Emerald green, there is soft spinule on surface.Pomegranate described herein originates from Mengzi Yunnan；This paper Chinese gooseberry originates from Jiangshan of Zhejiang Province city；
Coconut originates from Thailand；Rosa roxburghii Tratt originates from Guizhou；Sea-buckthorn is from the Inner Mongol Hetao area.Certainly, the above-mentioned fresh of other areas is originated from
Squeezing fruit and vegetable juice is also that can be used.
The carbohydrate is one of gossypose, oligofructose, galactooligosaccharide, inulin or their any mass ratio
Mixture；Wherein gossypose purity is 99%, is purchased from Sinopharm Chemical Reagent Co., Ltd..Oligofructose purity is 99%, purchase
In Hefei Bo Mei biotechnology Co., Ltd.Galactooligosaccharide purity is 98%, is purchased from the Shanghai limited public affairs of leaf biotechnology forever
Department.Inulin purity is 90%, is purchased from Sangon Biotech (Shanghai) Co., Ltd..
A kind of preparation method with the composition safeguarded and restore the effect of skin Tiny ecosystem, it is characterised in that using following
Step:
A, the trunk natural sap of freezing is thawed at normal temperature, and is filtered with 5 microns of stainless steel filters, then press matter
Amount weighs filtered white birch myron, maple juice than 5 ~ 9:1, is uniformly mixed to obtain trunk natural sap；
B, by the Fresh Cucumber Juice of freezing, guava juice, Chinese gooseberry fruit juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice normal
Temperature is lower to thaw, and with 5 microns of stainless steel filters filterings, then 1:1:1:1:1:1 in mass ratio weigh filtered Fresh Cucumber Juice,
Guava juice, Chinese gooseberry fruit juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice are uniformly mixed to obtain fresh squeezing fruit and vegetable juice；
C, 10-40:6-30:1-5:3-6 in mass ratio weighs fresh squeezing vegetable obtained by trunk natural sap, step B obtained by step A
Fruit juice, carbohydrate and different malt, the carbohydrate be one of gossypose, oligofructose, galactooligosaccharide, inulin or they
Any quality is heated to 35-40 DEG C of stirring to being completely dissolved than mixture after mixing；Then it is spray-dried to get having
Maintenance and the composition for restoring the effect of skin Tiny ecosystem.
The process conditions that the present invention is spray-dried are 110 DEG C of inlet air temperature, and compressed air is than 100%, flow velocity 7.5mL
min-1, nebulizer pressure 40 ~ 50mm of pillar height, the spray dryer used is Bu Qi company, Switzerland B-290 type, after spray drying
Composition water content is lower than 10% mass ratio.
The INCI title of the white birch myron are as follows: silver birch juice (BETULA ALBA JUICE)；The INCI of the maple juice
Title are as follows: Acer negundo extract (ACER SACCHARUM (SUGAR MAPLE) EXTRACT)；The INCI title of the Fresh Cucumber Juice
Are as follows: Fresh Cucumber Juice (CUCUMIS SATIVUS (CUCUMBER) JUICE)；The INCI title of the guava juice are as follows: guava juice
(PUNICA GRANATUM FRUIT JUICE)；The INCI title of the coconut water are as follows: coconut water (COCOS NUCIFERA
(COCONUT) WATER)；The INCI title of the Blackthorn pear fruit-juice are as follows: Single Roxburgh Rose Fruit extract (ROSA ROXBURGHII FRUIT
EXTRACT)；The INCI title of the sea buckthorn juice are as follows: sea buckthorn juice (HIPPOPHAE RHAMNOIDES FRUIT JUICE)；
The INCI title of the Chinese gooseberry fruit juice are as follows: Chinese gooseberry fruit juice (ACTINIDIA CHINENSIS (KIWI)
FRUIT JUICE)；The INCI title of the gossypose are as follows: gossypose (RAFFINOSE)；The INCI title of the oligofructose
Are as follows: oligofructose (FRUCTOOLIGOSACCHARIDES)；The INCI title of the galactooligosaccharide are as follows: galactooligosaccharide
(GALACTOOLIGOSACCHARIDES)；The INCI title of the inulin are as follows: inulin (INULIN)；The INCI of the different malt
Title are as follows: different malt (ISOMALT).
Have the composition water dispersible safeguarded and restore skin Tiny ecosystem good with prepared by the method for the present invention, it can be normal
It is added in pure water or ordinary cosmetics formula with mass ratio for 1-5% ratio under temperature, it is easy to use, there is maintenance and restore
The effect of skin Tiny ecosystem.
The solution of usual trunk natural sap and fresh squeezing fruit and vegetable juice, carbohydrate places one in non-be protected from light in glass container of room temperature
Week is easily oxidized in air because containing polyphenol or vitamin c class ingredient, and color becomes dark brown from faint yellow, and grows
Long microorganism, and the solution containing the above equivalent substance places one in non-be protected from light in glass container of room temperature after spray drying
Week, color still keep original faint yellow, because water content is lower than 10%, water activity is low, no microbial reproduction.
Above-mentioned trunk natural sap, fresh squeezing fruit and vegetable juice, carbohydrate isoreactivity composition are coordinated compounding by the present invention, can be repaired
Impaired skin improves skin micro-ecological environment.Dry grain structure can enhance the stability of active material, overcome tree
The shortcomings that dry natural sap, fresh squeezing fruit and vegetable juice, stability is poor in use for carbohydrate, active matter outward appearance change.
In conclusion being improved simultaneously the invention has the following advantages that skin normal flora Tiny ecosystem can be safeguarded and be restored
The stability and ease of use of active matter.The method that the present invention mentions also has preparation process simple, stable product quality, rule
The beneficial effects such as modelling is convenient for production.
Promote the confirmatory experiment of skin production antibacterial peptide
It takes and is tested in logarithmic growth phase keratinocyte, be divided into 9 groups: (1): the training without example IV composition
Nutrient solution；(2): the culture solution of the composition containing example IV；(3): composition containing example IV but the culture solution without Fresh Cucumber Juice；(4): containing
Example IV composition but culture solution without guava juice；(5): composition containing example IV but the training without Chinese gooseberry fruit juice
Nutrient solution；(6): composition containing example IV but the culture solution without coconut water；(7): composition containing example IV but without Blackthorn pear fruit-juice
Culture solution；(8): composition containing example IV but the culture solution without sea buckthorn juice；(9): composition containing example IV but without carbohydrate
Culture solution.Each composition concentration is 20 μ g/mL, and incubation time is for 24 hours.
Cathelicidin LL37 is the most common AMPs of human skin, with Cathelicidin LL37 product IOD value
Indicate the content of Cathelicidin LL-37 mRNA, with the ratio between β-actin IOD value with Cathelicidin LL37 and β-
The ratio between actin gray value indicates Cathelicidin LL37 protein content, to detect keratinocyte Cathelicidin
The expression of LL37 mRNA and albumen.Experiment is repeated 3 times, and reduces error.
The expression of table 1 Cathelicidin LL37 mRNA and albumen
From experimental group, (1) (2) data can be seen that keratinocyte after example IV compositions-treated,
The expression of Cathelicidin LL37 mRNA and albumen is significantly raised；From experimental group (1) (3) (4) (5) (6) (7) (8) (9) data
As can be seen that after lacking the example IV compositions-treated of special carbohydrate or in which a kind of fruit juice, Cathelicidin
Though the expression of LL37 mRNA and albumen increases, effect is not significant；It proves to contain special carbohydrate and six kinds above-mentioned
The example IV composition of fruit juice has the function of that skin is promoted to generate antibacterial peptide.
Confirmatory experiment with antiphlogistic effects
18 ~ 22g of weight healthy mice 50 is taken, half male and half female is randomly divided into 5 groups: (1): containing 10% example IV composition
Face cream；(2): the face cream containing 10% example IV composition but without white birch myron；(3): containing 10% example IV composition but without maple
The face cream of myron；(4): the face cream without example IV composition；(5): applying hydrocortisone.Each group dosage are as follows: 0.1g/ mouse.
It tests the 1st day, applies relative medicine to every mouse right ear exterior feature inner and outer respectively, dried up with hair dryer cold wind.
It was administered with the 1st day within 2nd day, uniformly applies 40 μ L caused by dimethylbenzene xylene inflammation after 30min is administered, in outside in mouse right ear exterior feature within the 3rd day, cause
It is administered again after scorching 30min, after causing inflammation 60min, etherization mouse, with spiral micrometer measurement mouse or so the same position of ear
Thickness, using two ear thickness differences as swelling.It causes cervical dislocation after inflammation 120min to put to death mouse, is taken respectively with 6mm punch
The auricle of lower left and right ear same position, sets on assay balance immediately and weighs, and subtracts left auricle quality as auricle using auris dextra tablet quality
Swelling.It the results are shown in Table 2:
The influence of 2 example IV composition paraxylene of table induction mouse ear swelling degree
As can be seen from Table 2, after smearing example IV composition face cream, the auricle swelling degree of infecting mouse, which has, significantly to be subtracted
Gently, after smearing the example IV composition face cream for lacking white birch myron or maple juice, though play the role of mitigating auricle swelling degree,
But effect is unobvious, illustrates that example IV composition has significant antiphlogistic effects.
Maintenance and the confirmatory experiment for restoring skin Tiny ecosystem
60 face portion acne patients are chosen, wherein male 28, female 32, the age 18-25 years old, the course of disease 1 ~ 2 year, wherein 30
People is used continuously 4 weeks, in addition 30 people are every daily morning and evening after face cleaning using the aqueous solution for preparing composition containing 10% example IV
It is applied after day morning and evening face cleaning and does not use any skin care item, be used continuously 4 weeks, as blank control；30 people of healthy control group separately is set, male
14, female 16.
Using sterile phosphate buffer (i.e. PBS, similarly hereinafter) cotton swab in face cleaning 4h or more acne lesions area (about 4cm ×
It 4cm) slightly firmly smears from inside to outside, cotton swab subheader is cut immediately with sterile after acquisition, is placed in and fills the sterile conveying liquid of 5ml
Test tube in, taken back in laboratory after being tightened with screw lid, the acne patient after treatment, method as above is adopted in skin lesion improvement region
Collection, health adult's sample, method as above hit exactly in facial forehead and acquire.Normal skin total plate count will be exceeded on patients with acne skin
Staphylococcus epidermis and propionibacterium acnes as representing flora, prepare the water-soluble of composition using containing 10% example IV
The statistics of flora and the facial pH value (pH value of normal human skin is 5.0-7.0) of test experiments personnel are carried out after liquid 30 days, it is real
It tests and the results are shown in Table 3:
3 experimenter's face flora count plate result of table and pH value
Note: number is count plate, that is, CFU/cm on skin every square centimeter in table2, indicated with Log10
Table 3 is experimenter's face flora count plate result and pH value, uses contain 10% example IV as shown in Table 3
Behind aqueous solution 30 days for preparing composition, under the flora number of acne human face staphylococcus epidermis and propionibacterium acnes is obvious
Drop be restored to normal level, facial pH value tends to normal level, though and blank control group face flora number and pH value make moderate progress,
But very slowly, illustrate that the product has the function of safeguarding and restoring skin microecological balance.
In white birch myron that the present invention selects, maple juice containing carbohydrate that is needed by human and easily absorbing, amino acid,
Organic acid and plurality of inorganic salt class can be adjusted rich in a variety of sugar and vitamins nutritional ingredients, selected sugar in selected fruit juice
Arthrobacter balance, enhances human immunological competence.The selected myron with different efficacies of the present invention, fruit and vegetable juice and sugar are compounded,
Skin Tiny ecosystem is safeguarded and restored by anti-inflammatory, promotion antibacterial peptide generation.Using spray drying technology by selected myron,
Particle is made in fruit and vegetable juice and sugar composite, and the stability of active constituent can be improved, and so that it is preferably played maintenance and restores skin
The effect of Tiny ecosystem, and it is able to maintain that it is non-discolouring at normal temperature, keep good appearance.
In conclusion composition prepared by the present invention have the effect of it is anti-inflammatory, promote antibacterial peptide generation, can safeguard and
Restore the health of skin Tiny ecosystem.
Specific embodiment
The embodiment enumerated below is the present invention to be described in more detail, but the present invention is not limited only to these realities
Apply example.
Embodiment one:
A kind of preparation method with the composition dry powder safeguarded and restore the effect of skin Tiny ecosystem, using following steps:
A, the trunk natural sap of freezing is thawed at normal temperature, and is filtered with 5 microns of stainless steel filters, weigh filtering
White birch myron 45.0g, maple juice 5.0g afterwards are uniformly mixed to obtain trunk natural sap；
B, by the Fresh Cucumber Juice of freezing, guava juice, Chinese gooseberry fruit juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice normal
Temperature is lower to thaw, and is filtered with 5 microns of stainless steel filters, weighs filtered Fresh Cucumber Juice, guava juice, Chinese gooseberry fruit
Each 5.0g of juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice is uniformly mixed to obtain fresh squeezing fruit and vegetable juice；
C, gossypose 3.0g, inulin 2.0g, different malt 15.0g and step A gained trunk natural sap, step B institute are weighed
Fresh squeezing fruit and vegetable juice is obtained in 35 DEG C of stirrings to after being completely dissolved, carrying out spray drying can be obtained with maintenance and the recovery micro- life of skin
The composition dry powder of state.Spray condition is Switzerland Bu Qi company B-290 spray dryer, spray drying condition: inlet air temperature 110
DEG C, compressed air is than 100%, flow velocity 7.5mLmin-1, 40 ~ 50mm of nebulizer pressure pillar height.
In the composition, trunk natural sap total content is 50.0%, and fresh squeezing fruit and vegetable juice total content is 30.0%, and carbohydrate always contains
Amount is 5.0%, and different malt content is 15.0%.
Embodiment two:
A kind of preparation method with the composition safeguarded and restore the effect of skin Tiny ecosystem, using following steps:
A, the trunk natural sap of freezing is thawed at normal temperature, and is filtered with 5 microns of stainless steel filters, weigh filtering
White birch myron 70.0g, maple juice 10.0g afterwards are uniformly mixed to obtain trunk natural sap；
B, by the Fresh Cucumber Juice of freezing, guava juice, Chinese gooseberry fruit juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice normal
Temperature is lower to thaw, and is filtered with 5 microns of stainless steel filters, weighs filtered Fresh Cucumber Juice, guava juice, Chinese gooseberry fruit
Each 2.0g of juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice is uniformly mixed to obtain fresh squeezing fruit and vegetable juice；
C, oligofructose 2.0g, different malt 6.0g are weighed, with fresh squeezing vegetable obtained by trunk natural sap, step B obtained by step A
In 35 DEG C of stirrings to after being completely dissolved, carry out spray drying can be obtained with the combination for safeguarding and restoring skin Tiny ecosystem fruit juice
Object dry powder.Spray condition is Switzerland Bu Qi company B-290 spray dryer, spray drying condition: 110 DEG C of inlet air temperature, is compressed
Air is than 100%, flow velocity 7.5mLmin-1, 40 ~ 50mm of nebulizer pressure pillar height.
In the composition, trunk natural sap total content is 80.0%, and fresh squeezing fruit and vegetable juice total content is 12.0%, and carbohydrate always contains
Amount is 2.0%, and different malt content is 6.0%.
Embodiment three:
A kind of preparation method with the composition safeguarded and restore the effect of skin Tiny ecosystem, using following steps:
A, the trunk natural sap of freezing is thawed at normal temperature, and is filtered with 5 microns of stainless steel filters, weigh filtering
White birch myron 48.0g, maple juice 8.0g afterwards are uniformly mixed to obtain trunk natural sap；
B, by the Fresh Cucumber Juice of freezing, guava juice, Chinese gooseberry fruit juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice normal
Temperature is lower to thaw, and is filtered with 5 microns of stainless steel filters, weighs filtered Fresh Cucumber Juice, guava juice, Chinese gooseberry fruit
Each 4.0g of juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice is uniformly mixed to obtain fresh squeezing fruit and vegetable juice；
C, gossypose 3.0g, oligofructose 2.0g, galactooligosaccharide 2.0g, inulin 3.0g, different malt 10.0g are weighed, with
Fresh squeezing fruit and vegetable juice obtained by trunk natural sap, step B obtained by step A to after being completely dissolved, is spray-dried in 38 DEG C of stirrings
It can be obtained with the composition dry powder for safeguarding and restoring skin Tiny ecosystem.Spray condition is spraying for Switzerland Bu Qi company B-290
Drying machine, spray drying condition: 110 DEG C of inlet air temperature, compressed air is than 100%, flow velocity 7.5mLmin-1, nebulizer pressure column
High 40 ~ 50mm.
In the composition, trunk natural sap total content is 56.0%, and fresh squeezing fruit and vegetable juice total content is 24.0%, and carbohydrate always contains
Amount is 10.0%, and different malt content is 10.0%.
Example IV:
A kind of preparation method with the composition safeguarded and restore the effect of skin Tiny ecosystem, using following steps:
A, the trunk natural sap of freezing is thawed at normal temperature, and is filtered with 5 microns of stainless steel filters, weigh filtering
White birch myron 25.0g, maple juice 5.0g afterwards are uniformly mixed to obtain trunk natural sap；
B, by the Fresh Cucumber Juice of freezing, guava juice, Chinese gooseberry fruit juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice normal
Temperature is lower to thaw, and is filtered with 5 microns of stainless steel filters, weighs filtered Fresh Cucumber Juice, guava juice, Chinese gooseberry fruit
Each 10.0g of juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice is uniformly mixed to obtain fresh squeezing fruit and vegetable juice；
C, gossypose 2.0g, galactooligosaccharide 2.0g, inulin 2.0g, different malt 4.0g are weighed, with trunk day obtained by step A
In 40 DEG C of stirrings to after being completely dissolved, carry out spray drying can be obtained with maintenance fresh squeezing fruit and vegetable juice obtained by right juice, step B
With the composition dry powder for restoring skin Tiny ecosystem.Spray condition is Switzerland Bu Qi company B-290 spray dryer, is spray-dried item
Part: 110 DEG C of inlet air temperature, compressed air is than 100%, flow velocity 7.5mLmin-1, 40 ~ 50mm of nebulizer pressure pillar height.
In the composition, trunk natural sap total content is 30.0%, and fresh squeezing fruit and vegetable juice total content is 60.0%, and carbohydrate always contains
Amount is 6.0%, and different malt content is 4.0%.
Embodiment five:
A kind of preparation method with the composition safeguarded and restore the effect of skin Tiny ecosystem, using following steps:
A, the trunk natural sap of freezing is thawed at normal temperature, and is filtered with 5 microns of stainless steel filters, weigh filtering
White birch myron 48.0g, maple juice 6.0g afterwards are uniformly mixed to obtain trunk natural sap；
B, by the Fresh Cucumber Juice of freezing, guava juice, Chinese gooseberry fruit juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice normal
Temperature is lower to thaw, and is filtered with 5 microns of stainless steel filters, weighs filtered Fresh Cucumber Juice, guava juice, Chinese gooseberry fruit
Each 4.0g of juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice is uniformly mixed to obtain fresh squeezing fruit and vegetable juice；
C, gossypose 4.0g, oligofructose 2.0g, inulin 4.0g, different malt 12.0g are weighed, with trunk day obtained by step A
In 40 DEG C of stirrings to after being completely dissolved, carry out spray drying can be obtained with maintenance fresh squeezing fruit and vegetable juice obtained by right juice, step B
With the composition dry powder for restoring skin Tiny ecosystem.Spray condition is Switzerland Bu Qi company B-290 spray dryer, is spray-dried item
Part: 110 DEG C of inlet air temperature, compressed air is than 100%, flow velocity 7.5mLmin-1, 40 ~ 50mm of nebulizer pressure pillar height.
In the composition, trunk natural sap total content is 54.0%, and fresh squeezing fruit and vegetable juice total content is 24.0%, and carbohydrate always contains
Amount is 10.0%, and different malt content is 12.0%.
Claims (3)
1. a kind of with the composition for safeguarding and restoring the effect of skin Tiny ecosystem, it is characterised in that including following components: mass ratio
For the trunk natural sap of 10-40:6-30:1-5:3-6, fresh squeezing fruit and vegetable juice, carbohydrate and different malt；The trunk natural sap by
White birch myron, maple juice 5-9:1 in mass ratio are mixed；The fresh squeezing fruit and vegetable juice be Fresh Cucumber Juice, guava juice, coconut water,
Blackthorn pear fruit-juice, sea buckthorn juice, Chinese gooseberry fruit juice etc. quality compare mixture；The carbohydrate is gossypose, oligofructose, low
One of poly- galactolipin, inulin or their any quality compare mixture.
2. a kind of composition with maintenance and recovery skin Tiny ecosystem effect according to claim 1, characteristic are:
Birch skin brain mass content >=0.14% in the white birch myron, maple sugar mass content >=3.5% in the maple juice, the Huang
Content of vitamin E >=0.5mg/100g in melon juice, polyphenol content >=143mg/100g in the guava juice, the coconut
Potassium content >=230mg/100ml in water, superoxide dismutase >=450u/g in the Blackthorn pear fruit-juice, the sea buckthorn juice
In general flavone >=4.1mg/100g, Vitamin C content >=300mg/100g in the Chinese gooseberry fruit juice.
3. a kind of preparation method with the composition safeguarded and restore the effect of skin Tiny ecosystem, it is characterised in that use following step
It is rapid:
A, the trunk natural sap of freezing is thawed at normal temperature, and is filtered with 5 microns of stainless steel filters, then in mass ratio
5 ~ 9:1 weighs filtered white birch myron, maple juice, is uniformly mixed to obtain trunk natural sap；
B, at normal temperature by the Fresh Cucumber Juice of freezing, guava juice, Chinese gooseberry fruit juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice
It thaws, and is filtered with 5 microns of stainless steel filters, then 1:1:1:1:1:1 in mass ratio weighs filtered Fresh Cucumber Juice, pomegranate
Fruit juice, Chinese gooseberry fruit juice, coconut water, Blackthorn pear fruit-juice, sea buckthorn juice are uniformly mixed to obtain fresh squeezing fruit and vegetable juice；
C, 10-40:6-30:1-5:3-6 in mass ratio weighs fresh squeezing vegetables and fruits obtained by trunk natural sap, step B obtained by step A
Juice, carbohydrate and different malt, the carbohydrate are one of gossypose, oligofructose, galactooligosaccharide, inulin or their times
Quality of anticipating is heated to 35-40 DEG C of stirring to being completely dissolved than mixture after mixing；Then it is spray-dried to get having dimension
Shield and the composition for restoring the effect of skin Tiny ecosystem.
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| FR3080285B1 (en) * | 2018-04-20 | 2020-12-04 | Lvmh Rech | COSMETIC COMPOSITION INCLUDING AN AQUEOUS ROSE FRUIT EXTRACT |
| CN109044929B (en) * | 2018-09-14 | 2021-05-25 | 陶萍 | Skin care lotion with moisturizing, anti-aging, whitening and freckle removing functions |
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| CN103622901A (en) * | 2013-11-21 | 2014-03-12 | 广州立白企业集团有限公司 | Skin cleaner composition capable of regulating microecological balance of skin and preparation method thereof |
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| CN105662940A (en) * | 2016-01-05 | 2016-06-15 | 深圳典立生物科技有限公司 | Active composition, and preparation method and application thereof in cosmetics or skin care products |
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| US20170156999A1 (en) * | 2015-12-03 | 2017-06-08 | The Dial Corporation | Personal care composition in a dissolvable container |
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