CN107374587A - A kind of the OCT image conduit and application method of integrated blood flow reserve fraction detection - Google Patents
A kind of the OCT image conduit and application method of integrated blood flow reserve fraction detection Download PDFInfo
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- CN107374587A CN107374587A CN201710581004.7A CN201710581004A CN107374587A CN 107374587 A CN107374587 A CN 107374587A CN 201710581004 A CN201710581004 A CN 201710581004A CN 107374587 A CN107374587 A CN 107374587A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0066—Optical coherence imaging
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
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Abstract
A kind of the OCT image conduit and application method of integrated blood flow reserve fraction detection, it is described to enter to note the injection that section is used for contrast agent；The plug receptacle connects equipment；The intervention section center is optical fiber；The optical fiber front end is prism；The outer fiber coats bourdon tube；Prism pillar is provided with outside the prism；The prism pillar is connected with bourdon tube；It is inner protective tube outside the bourdon tube, inner protective tube front end is provided with thread eye；FFR pressure sensors are arranged on the outside of inner protective tube, FFR pressure sensor Surface coating outer protection tubes, and outer protection tube is provided with detection window at the FFR pressure sensors.The OCT image conduit of the present invention is integrated with the detection of blood flow reserve fraction, the combination of two kinds of technologies not only optimizes PCI Treatment decsions, improve the accuracy of medical diagnosis on disease, and intravasation once completes two kinds of detections, shorten the operating time, alleviate patient suffering, reduce apparatus expense, operation risk is reduced, great convenience is provided for detection.
Description
【Technical field】
The present invention relates to the intervention diagnosis and therapy field of coronary heart disease, more particularly to a kind of OCT image of integrated blood flow reserve fraction detection
Conduit and application method.
【Background technology】
China's incidence of coronary heart disease is still in increase situation year by year, and percutaneous coronary intervention (pci)（PCI）It is treatment coronary heart disease
Major measure.The relation of stenotic lesion and myocardial ischemia is correctly identified, i.e. lesion function assessment is evaluated, and selects preferably treatment plan
Slightly, most important to improving patient's long-term prognosis, the theory of Interventional cardiology changes, i.e., from pursuit anatomy blood
Transport reconstruction changes to the function assessment revascularization for the purpose of improving myocardial ischemia.
Blood flow reserve fraction (Fractional Flow Reserve, abbreviation FFR) be 1993 propose pass through pressure
Power measure calculates the New Set of coronary blood flow, and it is defined as stenosed coronary arteries and dominates regional myocardial maximum blood flow and same branch
Ratio of the coronary artery without stenosis cardiac muscle maximum blood flow.Safety, economy, and energy are proved with the FFR therapeutic strategies instructed
Improve patient's prognosis, be increasingly becoming generally acknowledged invasive lesion function assessment evaluation index.FFR is to judge myocardial ischemia at present, instruct
New " goldstandard " of PCI.FFR measurements are easy to operate, safely, quickly, available for different lesions（Single branch coronary artery
Borderline lesion, multivessel coronary artery disease, bifurcated lesions, series connection or diffusivity lesion, Left main stem disease）Commented with after stenting
Estimate, the selection of guiding clinical treatment strategy and judging prognosis.Guide is suggested both at home and abroad at present, should be conventional for borderline lesion
FFR inspections are carried out, with guiding clinical treatment decision-making.
Optical coherence tomography (Optical Coherence Tomography, abbreviation OCT) applies modern computer
Image procossing, advanced optical technology and hypersensitive detector are integrated, have evolved into a kind of emerging fault imaging and examine
Disconnected technology.OCT is current resolution highest intracavitary Imaging Technology, and axial resolution can reach 10 microns, while be imaged speed
Degree is fast, can detect the microstructure inside biological tissue, be referred to as " optical biopsy ".At the same time, due to itself and pathologic group
Knitting image has good correspondence, can diagnose and evaluate coronary plaque on histological level is similar to, so as to
Allow people to more fully understand the Pathologic Characteristics of coronary artery disease, and controlled for the own characteristic progress individuation of different patients
Treat.Therefore OCT is in the intervention diagnosis of coronary artery pathological changes, guidance of interventional treatment strategy and evaluation interventional therapeutic effect etc. tool
There is more and more important clinical value.
OCT is mainly used in the Senile Mouse of patch in clinic at present, and ignores it and judge coronary artery blood supply situation
Function assessment value, therefore, it is by the aspect resolution ratio highest technology and work(of morphology at this stage that OCT is combined with FFR technologies
The reliability index that can be learned effectively is combined, and accuracy is not only increased to medical diagnosis on disease, and intravasation once completes two kinds of detections, contracting
The short operation time, patient suffering is alleviated, reduce apparatus expense, reduce operation risk, great convenience is provided for detection.
【The content of the invention】
The problem to be solved in the present invention is to provide a kind of the OCT image conduit and application method of integrated blood flow reserve fraction detection,
Optimize PCI Treatment decsions, improve the medical diagnosis on disease degree of accuracy, reduce patient suffering, offered convenience to medical personnel.
A kind of the OCT image conduit and application method of integrated blood flow reserve fraction detection, including plug receptacle, enter and note section, be situated between
Enter section, maincenter pipe, FFR pressure sensors；The conduit is provided with maincenter pipe, and the maincenter pipe with plug receptacle, enters to note section respectively,
Intervention section is connected；It is described to enter to note the injection that section is used for contrast agent；The plug receptacle connects equipment；The intervention section center is light
It is fine；The optical fiber front end is prism；The outer fiber coats bourdon tube；Prism pillar is provided with outside the prism；The rib
Mirror pillar is connected with bourdon tube；It is inner protective tube outside the bourdon tube, inner protective tube front end is provided with thread eye；FFR pressure sensors
It is arranged on the outside of inner protective tube, FFR pressure sensor Surface coating outer protection tubes, outer protection tube is provided with inspection at the FFR pressure sensors
Survey window.
Further, the prism pillar is made up of the good material of translucency.
Further, the outer protection tube is made up of the good material of translucency.
Further, the inner protective tube is made up of the good material of translucency.
Further, step includes：
A. by conduit plug receptacle connect equipment, by seal wire pass through catheter proximal end thread eye, under the guide of seal wire by conduit before
Blood vessel is stretched at end, and prism is scanned, and finds focus narrow positions accurately；
B. after carrying out pressure calibration, Pa and Pd values are surveyed, record FFR values.
C. conduit is withdrawn from from blood vessel, completes operation.
Beneficial effects of the present invention：A kind of the OCT image conduit and application method of integrated blood flow reserve fraction detection, will
OCT technology combines with FFR technologies, not only optimizes PCI Treatment decsions, improves the accuracy of medical diagnosis on disease, Er Qiejin
Enter blood vessel and once complete two kinds of detections, shorten the operating time, alleviate patient suffering, reduce apparatus expense, reduce operation
Risk, great convenience is provided for detection.
【Brief description of the drawings】
The present invention is described in further detail with reference to the accompanying drawings and detailed description.
Fig. 1 is the structural representation of the OCT image conduit of the integrated blood flow reserve fraction detection of the present invention.
Label declaration in figure：1- plug receptacles, 2-, which enters, notes section, 3- maincenter pipes, 4- intervention sections, 5-FFR pressure sensors, 6-
Detect window, 7- outer protection tubes, 8- thread eyes, 9- inner protective tubes, 10- prism pillars, 11- prisms, 12- bourdon tubes.
【Embodiment】
To be easy to understand the technical means, the inventive features, the objects and the advantages of the present invention, with reference to specific
Embodiment, the present invention is expanded on further.
The present invention is described in further detail with reference to the accompanying drawings and detailed description.
As shown in figure 1, a kind of the OCT image conduit and application method of integrated blood flow reserve fraction detection, including plug receptacle
1, enter to note section 2, intervene section 4, maincenter pipe 3, FFR pressure sensors 5；The conduit is provided with maincenter pipe 3, and the maincenter pipe 3 divides
Not with plug receptacle 1, enter to note section 2, intervention section 4 is connected；It is described to enter to note the injection that section 2 is used for contrast agent；The connection of plug receptacle 1 is set
It is standby；Intervention section 4 center is optical fiber；The optical fiber front end is prism 11；The outer fiber coats bourdon tube 12；The rib
The outside of mirror 11 is provided with prism pillar 10；The prism pillar 10 is connected with bourdon tube 12；The outside of bourdon tube 12 is inner protective tube
9, the front end of inner protective tube 9 is provided with thread eye 8；FFR pressure sensors 5 are arranged at the outside of inner protective tube 9, the surface of FFR pressure sensors 5 bag
Outer protection tube 7 is covered, outer protection tube 7 is provided with detection window 6 at the FFR pressure sensors 5.
The use process of the conduit of the present invention is as follows：Carry out OCT detections：Conduit plug receptacle is connected into equipment, seal wire is worn
The thread eye of catheter proximal end is crossed, catheter proximal end is stretched into blood vessel under the guide of seal wire, prism is scanned, and it is narrow to find focus accurately
Position；Carry out FFR detections：After carrying out pressure calibration, Pa and Pd values are surveyed, record FFR values；Conduit is withdrawn from from blood vessel, completes hand
Art.
Wherein, the prism pillar 10 is made up of the good material of translucency.
Wherein, the outer protection tube 7 is made up of the good material of translucency.
Wherein, the inner protective tube 9 is made up of the good material of translucency.
The general principle and principal character and advantages of the present invention of the present invention has been shown and described above.The technology of the industry
Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the simply explanation described in above-described embodiment and specification is originally
The principle of invention, without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, these changes
Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its
Equivalent thereof.
Claims (5)
1. a kind of the OCT image conduit and application method of integrated blood flow reserve fraction detection, including plug receptacle, enter and note section, intervene
Section, maincenter pipe, FFR pressure sensors；It is characterized in that：
The conduit is provided with maincenter pipe, and the maincenter pipe with plug receptacle, enters respectively and notes section, and intervention section is connected；It is described to enter to note section
Injection for contrast agent；The plug receptacle connects equipment；The intervention section center is optical fiber；The optical fiber front end is prism；
The outer fiber coats bourdon tube；Prism pillar is provided with outside the prism；The prism pillar is connected with bourdon tube；It is described
It is inner protective tube outside bourdon tube, inner protective tube front end is provided with thread eye；FFR pressure sensors are arranged on the outside of inner protective tube, FFR pressure
Sensor surface coats outer protection tube, and outer protection tube is provided with detection window at the FFR pressure sensors.
2. the OCT image conduit and application method of a kind of integrated blood flow reserve fraction detection according to claim 1, it is special
Sign is：The prism pillar is made up of the good material of translucency.
3. a kind of the OCT image conduit and application method of integrated blood flow reserve fraction detection according to claim 1, its feature
It is：The outer protection tube is made up of the good material of translucency.
4. the OCT image conduit and application method of a kind of integrated blood flow reserve fraction detection according to claim 1, it is special
Sign is：The inner protective tube is made up of the good material of translucency.
5. the OCT image conduit and application method of a kind of integrated blood flow reserve fraction detection according to claim 1, it is special
Sign is：Step includes：
A. by conduit plug receptacle connect equipment, by seal wire pass through catheter proximal end thread eye, under the guide of seal wire by conduit before
Blood vessel is stretched at end, and prism is scanned, and finds focus narrow positions accurately；
B. after carrying out pressure calibration, Pa and Pd values are surveyed, record FFR values；
C. conduit is withdrawn from from blood vessel, completes operation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710581004.7A CN107374587A (en) | 2017-07-17 | 2017-07-17 | A kind of the OCT image conduit and application method of integrated blood flow reserve fraction detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710581004.7A CN107374587A (en) | 2017-07-17 | 2017-07-17 | A kind of the OCT image conduit and application method of integrated blood flow reserve fraction detection |
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| Publication Number | Publication Date |
|---|---|
| CN107374587A true CN107374587A (en) | 2017-11-24 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710581004.7A Pending CN107374587A (en) | 2017-07-17 | 2017-07-17 | A kind of the OCT image conduit and application method of integrated blood flow reserve fraction detection |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109567776A (en) * | 2018-12-31 | 2019-04-05 | 深圳北芯生命科技有限公司 | For testing the catheter simulation device of FFR host system |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102469943A (en) * | 2009-07-14 | 2012-05-23 | 通用医疗公司 | Apparatus, systems and methods for measuring flow and pressure within a vessel |
| US20140094697A1 (en) * | 2011-05-27 | 2014-04-03 | Lightlab Imaging, Inc. | Optical coherence tomography and pressure based systems and methods |
| CN105054901A (en) * | 2015-08-26 | 2015-11-18 | 张文保 | Single-optical-fiber endoscope system integrated with optical coherence tomography and fractional flow reserve detection |
| CN105228514A (en) * | 2013-03-15 | 2016-01-06 | 阿维格公司 | Optical pressure sensor assembly |
| CN105283119A (en) * | 2013-04-12 | 2016-01-27 | 皇家飞利浦有限公司 | Shape sensed ultrasound probe for fractional flow reserve simulation |
| CN106691405A (en) * | 2016-12-29 | 2017-05-24 | 天津恒宇医疗科技有限公司 | Superfine OCT (optical coherence tomography) imaging catheter |
-
2017
- 2017-07-17 CN CN201710581004.7A patent/CN107374587A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102469943A (en) * | 2009-07-14 | 2012-05-23 | 通用医疗公司 | Apparatus, systems and methods for measuring flow and pressure within a vessel |
| US20140094697A1 (en) * | 2011-05-27 | 2014-04-03 | Lightlab Imaging, Inc. | Optical coherence tomography and pressure based systems and methods |
| CN105228514A (en) * | 2013-03-15 | 2016-01-06 | 阿维格公司 | Optical pressure sensor assembly |
| CN105283119A (en) * | 2013-04-12 | 2016-01-27 | 皇家飞利浦有限公司 | Shape sensed ultrasound probe for fractional flow reserve simulation |
| CN105054901A (en) * | 2015-08-26 | 2015-11-18 | 张文保 | Single-optical-fiber endoscope system integrated with optical coherence tomography and fractional flow reserve detection |
| CN106691405A (en) * | 2016-12-29 | 2017-05-24 | 天津恒宇医疗科技有限公司 | Superfine OCT (optical coherence tomography) imaging catheter |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109567776A (en) * | 2018-12-31 | 2019-04-05 | 深圳北芯生命科技有限公司 | For testing the catheter simulation device of FFR host system |
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Application publication date: 20171124 |